Frank V. Murphy, Ph.D.
Affiliations: | 2000 | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
Area:
Biochemistry, General Biophysics, Molecular BiologyGoogle:
"Frank Murphy"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Mair E. A. Churchill | grad student | 2000 | UIUC | |
| (Structural studies of HMG-D-DNA interactions.) | ||||
| Venkatraman Ramakrishnan | post-doc | MRC-LMB (Chemistry Tree) | ||
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Publications
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| Vangaveti S, Cantara WA, Spears JL, et al. (2020) A structural basis for restricted codon recognition mediated by 2-thiocytidine in tRNA containing a wobble position inosine. Journal of Molecular Biology |
| Demirci H, Murphy FV, Murphy EL, et al. (2014) Structural analysis of base substitutions in Thermus thermophilus 16S rRNA conferring streptomycin resistance. Antimicrobial Agents and Chemotherapy. 58: 4308-17 |
| Demirci H, Wang L, Murphy FV, et al. (2013) The central role of protein S12 in organizing the structure of the decoding site of the ribosome. Rna (New York, N.Y.). 19: 1791-801 |
| Demirci H, Murphy F, Murphy E, et al. (2013) A structural basis for streptomycin-induced misreading of the genetic code. Nature Communications. 4: 1355 |
| Vendeix FA, Murphy FV, Cantara WA, et al. (2012) Human tRNA(Lys3)(UUU) is pre-structured by natural modifications for cognate and wobble codon binding through keto-enol tautomerism. Journal of Molecular Biology. 416: 467-85 |
| Demirci H, Murphy F, Belardinelli R, et al. (2010) Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function. Rna (New York, N.Y.). 16: 2319-24 |
| Schmeing TM, Voorhees RM, Kelley AC, et al. (2009) The crystal structure of the ribosome bound to EF-Tu and aminoacyl-tRNA. Science (New York, N.Y.). 326: 688-94 |
| Schuette JC, Murphy FV, Kelley AC, et al. (2009) GTPase activation of elongation factor EF-Tu by the ribosome during decoding. The Embo Journal. 28: 755-65 |
| Weixlbaumer A, Murphy FV, Dziergowska A, et al. (2007) Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines. Nature Structural & Molecular Biology. 14: 498-502 |
| Selmer M, Dunham CM, Murphy FV, et al. (2006) Structure of the 70S ribosome complexed with mRNA and tRNA. Science (New York, N.Y.). 313: 1935-42 |