Jonathan Wanagat, Ph.D.

2000 University of Wisconsin, Madison, Madison, WI 
Cell Biology, Molecular Biology, Pathology
"Jonathan Wanagat"
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Judd M. Aiken grad student 2000 UW Madison
 (The role of mitochondrial DNA deletion mutations in the pathogenesis of aging: Studies in rodent heart and skeletal muscle.)
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Bielas J, Herbst A, Widjaja K, et al. (2018) Long term rapamycin treatment improves mitochondrial DNA quality in aging mice. Experimental Gerontology
Herbst A, Widjaja K, Nguy B, et al. (2017) Digital PCR Quantitation of Muscle Mitochondrial DNA: Age, Fiber Type, and Mutation-Induced Changes. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences
Herbst A, Wanagat J, Cheema N, et al. (2016) Latent mitochondrial DNA deletion mutations drive muscle fiber loss at old age. Aging Cell
Wanagat J, Hevener AL. (2016) Mitochondrial quality control in insulin resistance and diabetes. Current Opinion in Genetics & Development. 38: 118-126
Ribas V, Drew BG, Zhou Z, et al. (2016) Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Science Translational Medicine. 8: 334ra54
Wanagat J, Ahmadieh N, Bielas JH, et al. (2015) Skeletal muscle mitochondrial DNA deletions are not increased in CuZn-superoxide dismutase deficient mice. Experimental Gerontology. 61: 15-9
Drew BG, Ribas V, Le JA, et al. (2014) HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle. Diabetes. 63: 1488-505
Ahuja P, Wanagat J, Wang Z, et al. (2013) Divergent mitochondrial biogenesis responses in human cardiomyopathy. Circulation. 127: 1957-67
Wanagat J, Dai DF, Rabinovitch P. (2010) Mitochondrial oxidative stress and mammalian healthspan. Mechanisms of Ageing and Development. 131: 527-35
Kulawiec M, Salk JJ, Ericson NG, et al. (2010) Generation, function, and prognostic utility of somatic mitochondrial DNA mutations in cancer. Environmental and Molecular Mutagenesis. 51: 427-39
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