Jonathan Wanagat, Ph.D.

Affiliations: 
2000 University of Wisconsin, Madison, Madison, WI 
Area:
Cell Biology, Molecular Biology, Pathology
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"Jonathan Wanagat"
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Judd M. Aiken grad student 2000 UW Madison
 (The role of mitochondrial DNA deletion mutations in the pathogenesis of aging: Studies in rodent heart and skeletal muscle.)
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Publications

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Vandiver AR, Hoang AN, Herbst A, et al. (2023) Nanopore sequencing identifies a higher frequency and expanded spectrum of mitochondrial DNA deletion mutations in human aging. Aging Cell. e13842
Herbst A, Choi S, Hoang AN, et al. (2022) Remdesivir does not affect mitochondrial DNA copy number or deletion mutation frequency in aged male rats: A short report. Plos One. 17: e0271850
Herbst A, Aiken JM, Kim C, et al. (2022) Age- and time-dependent mitochondrial genotoxic and myopathic effects of beta-guanidinopropionic acid, a creatine analog, on rodent skeletal muscles. Geroscience
Vandiver AR, Pielstick B, Gilpatrick T, et al. (2022) Long read mitochondrial genome sequencing using Cas9-guided adaptor ligation. Mitochondrion. 65: 176-183
Herbst A, Hoang A, Kim C, et al. (2021) Metformin treatment in old rats and effects on mitochondrial integrity. Rejuvenation Research
Herbst A, Prior SJ, Lee CC, et al. (2021) Skeletal muscle mitochondrial DNA copy number and mitochondrial DNA deletion mutation frequency as predictors of physical performance in older men and women. Geroscience
Moore TM, Zhou Z, Strumwasser AR, et al. (2020) Age-induced mitochondrial DNA point mutations are inadequate to alter metabolic homeostasis in response to nutrient challenge. Aging Cell. e13166
Herbst A, Lee CC, Vandiver AR, et al. (2020) Mitochondrial DNA deletion mutations increase exponentially with age in human skeletal muscle. Aging Clinical and Experimental Research
Barthelemy F, Woods JD, Nieves-Rodriguez S, et al. (2020) A well tolerated core needle muscle biopsy process suitable for children and adults. Muscle & Nerve
Zhou Z, Moore TM, Drew BG, et al. (2020) Estrogen receptor α controls metabolism in white and brown adipocytes by regulating and mitochondrial remodeling. Science Translational Medicine. 12
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