Zhizhan Gu, M.D., Ph.D.

2007 Brown University, Providence, RI 
Pharmacology, Physiology, Biotechnology
"Zhizhan Gu"
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Law RA, Kiepas A, Desta HE, et al. (2023) Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement. Science Advances. 9: eabq6480
Hui TH, Cho WC, Fong HW, et al. (2019) An electro-osmotic microfluidic system to characterize cancer cell migration under confinement. Journal of the Royal Society, Interface. 16: 20190062
Hung WC, Yang JR, Yankaskas CL, et al. (2016) Confinement-Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways. Cell Reports
Gu Z. (2014) 0.1 kilopascal difference for mechanophenotyping: soft matrix precisely regulates cellular architecture for invasion. Bioarchitecture. 4: 116-8
Stroka KM, Gu Z, Sun SX, et al. (2014) Bioengineering paradigms for cell migration in confined microenvironments. Current Opinion in Cell Biology. 30: 41-50
Gu Z, Liu F, Tonkova EA, et al. (2014) Soft matrix is a natural stimulator for cellular invasiveness. Molecular Biology of the Cell. 25: 457-69
Gu Z, Fonseca V, Hai CM. (2013) Nicotinic acetylcholine receptor mediates nicotine-induced actin cytoskeletal remodeling and extracellular matrix degradation by vascular smooth muscle cells. Vascular Pharmacology. 58: 87-97
Chen Y, Rice W, Gu Z, et al. (2012) Aquaporin 2 promotes cell migration and epithelial morphogenesis. Journal of the American Society of Nephrology : Jasn. 23: 1506-17
Chang SK, Noss EH, Chen M, et al. (2011) Cadherin-11 regulates fibroblast inflammation. Proceedings of the National Academy of Sciences of the United States of America. 108: 8402-7
Gu Z, Noss EH, Hsu VW, et al. (2011) Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration. The Journal of Cell Biology. 193: 61-70
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