Andrea Frankel, Ph.D.

Affiliations: 
2002 University of Toronto, Toronto, ON, Canada 
Area:
Cell Biology, Oncology
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"Andrea Frankel"
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Robert S. Kerbel grad student 2002 University of Toronto
 (Targeting multicellular drug resistance mechanisms in ovarian cancer.)
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Publications

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Khoury O, Ghazale N, Stone E, et al. (2015) Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells. Journal of Neuro-Oncology. 122: 75-85
Angelot-Delettre F, Roggy A, Frankel AE, et al. (2015) In vivo and in vitro sensitivity of blastic plasmacytoid dendritic cell neoplasm to SL-401, an interleukin-3 receptor targeted biologic agent. Haematologica. 100: 223-30
Tanios R, Bekdash A, Kassab E, et al. (2013) Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells. Leukemia Research. 37: 1565-71
Agrawal V, Woo JH, Mauldin JP, et al. (2012) Cytotoxicity of human recombinant arginase I (Co)-PEG5000 in the presence of supplemental L-citrulline is dependent on decreased argininosuccinate synthetase expression in human cells. Anti-Cancer Drugs. 23: 51-64
Frankel A, Rosen K, Filmus J, et al. (2001) Induction of anoikis and suppression of human ovarian tumor growth in vivo by down-regulation of Bcl-X(L). Cancer Research. 61: 4837-41
Frankel A, Man S, Elliott P, et al. (2000) Lack of multicellular drug resistance observed in human ovarian and prostate carcinoma treated with the proteasome inhibitor PS-341. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 6: 3719-28
Green SK, Frankel A, Kerbel RS. (1999) Adhesion-dependent multicellular drug resistance. Anti-Cancer Drug Design. 14: 153-68
Frankel A, Buckman R, Kerbel RS. (1997) Abrogation of taxol-induced G2-M arrest and apoptosis in human ovarian cancer cells grown as multicellular tumor spheroids. Cancer Research. 57: 2388-93
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