Sylvia S. Ng, Ph.D.

Affiliations: 
2002 University of Toronto, Toronto, ON, Canada 
Area:
Pharmacology, Oncology
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David Hedley grad student 2002 University of Toronto
 (Preclinical evaluation of inhibitors of the phosphatidylinositide 3-kinase/protein kinase B cell survival pathway in the treatment of pancreatic cancer.)
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Publications

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Ng SS, Tsao MS, Nicklee T, et al. (2002) Effects of the epidermal growth factor receptor inhibitor OSI-774, Tarceva, on downstream signaling pathways and apoptosis in human pancreatic adenocarcinoma. Molecular Cancer Therapeutics. 1: 777-83
Ng SS, Tsao MS, Nicklee T, et al. (2001) Wortmannin inhibits pkb/akt phosphorylation and promotes gemcitabine antitumor activity in orthotopic human pancreatic cancer xenografts in immunodeficient mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 3269-75
Ng SSW, Tsao MS, Chow S, et al. (2000) Inhibition of phosphatidylinositide 3-kinase enhances gemcitabine-induced apoptosis in human pancreatic cancer cells. Cancer Research. 60: 5451-5
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