Sylvia S. Ng, Ph.D.

Affiliations: 
2002 University of Toronto, Toronto, ON, Canada 
Area:
Pharmacology, Oncology
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David Hedley grad student 2002 University of Toronto
 (Preclinical evaluation of inhibitors of the phosphatidylinositide 3-kinase/protein kinase B cell survival pathway in the treatment of pancreatic cancer.)
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Publications

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Yapp DT, Wong MQ, Kyle AH, et al. (2016) The differential effects of metronomic gemcitabine and antiangiogenic treatment in patient-derived xenografts of pancreatic cancer: treatment effects on metabolism, vascular function, cell proliferation, and tumor growth. Angiogenesis
Donohue E, Thomas A, Maurer N, et al. (2013) The autophagy inhibitor verteporfin moderately enhances the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model. Journal of Cancer. 4: 585-96
Ng SS, Figg WD. (2004) Upregulation of endogenous angiogenesis inhibitors: a mechanism of action of metronomic chemotherapy. Cancer Biology & Therapy. 3: 1212-3
Ng SS, Tsao MS, Nicklee T, et al. (2002) Effects of the epidermal growth factor receptor inhibitor OSI-774, Tarceva, on downstream signaling pathways and apoptosis in human pancreatic adenocarcinoma. Molecular Cancer Therapeutics. 1: 777-83
Ng SS, Tsao MS, Nicklee T, et al. (2001) Wortmannin inhibits pkb/akt phosphorylation and promotes gemcitabine antitumor activity in orthotopic human pancreatic cancer xenografts in immunodeficient mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 3269-75
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