David W. Bolen

Affiliations: 
University of Texas Medical Branch, Galveston, TX 
Area:
General Biophysics
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"David Bolen"
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Publications

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Auton M, Rösgen J, Sinev M, et al. (2011) Osmolyte effects on protein stability and solubility: a balancing act between backbone and side-chains. Biophysical Chemistry. 159: 90-9
Hu CY, Kokubo H, Lynch GC, et al. (2010) Backbone additivity in the transfer model of protein solvation. Protein Science : a Publication of the Protein Society. 19: 1011-22
Holthauzen LM, Rösgen J, Bolen DW. (2010) Hydrogen bonding progressively strengthens upon transfer of the protein urea-denatured state to water and protecting osmolytes. Biochemistry. 49: 1310-8
Street TO, Krukenberg KA, Rosgen J, et al. (2010) Osmolyte-induced conformational changes in the Hsp90 molecular chaperone. Protein Science : a Publication of the Protein Society. 19: 57-65
Schrank TP, Bolen DW, Hilser VJ. (2009) Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins. Proceedings of the National Academy of Sciences of the United States of America. 106: 16984-9
Bolen DW, Rose GD. (2008) Structure and energetics of the hydrogen-bonded backbone in protein folding. Annual Review of Biochemistry. 77: 339-62
Auton M, Bolen DW, Rösgen J. (2008) Structural thermodynamics of protein preferential solvation: osmolyte solvation of proteins, aminoacids, and peptides. Proteins. 73: 802-13
Auton M, Holthauzen LM, Bolen DW. (2007) Anatomy of energetic changes accompanying urea-induced protein denaturation. Proceedings of the National Academy of Sciences of the United States of America. 104: 15317-22
Auton M, Bolen DW. (2007) Application of the transfer model to understand how naturally occurring osmolytes affect protein stability. Methods in Enzymology. 428: 397-418
Gulotta M, Qiu L, Desamero R, et al. (2007) Effects of cell volume regulating osmolytes on glycerol 3-phosphate binding to triosephosphate isomerase. Biochemistry. 46: 10055-62
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