Jaeyeon Kim, Ph.D.

Affiliations: 
2008 Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
Biomedical Engineering
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Gerald M. Saidel grad student 2008 Case Western
 (Model analysis of adipose tissue and whole body metabolism in vivo.)
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Publications

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Clarke JL, Molinaro AM, Cabrera JR, et al. (2017) A phase 1 trial of intravenous liposomal irinotecan in patients with recurrent high-grade glioma. Cancer Chemotherapy and Pharmacology
Koshkaryev A, Fitzgerald J, Kim J, et al. (2016) Abstract 2075: Differential tissue clearance results in improved therapeutic index for irinotecan liposome injection (ONIVYDE) when combined with the PARP inhibitor veliparib in preclinical cervical tumors Cancer Research. 76: 2075-2075
Kalra AV, Kim J, Klinz SG, et al. (2014) Preclinical activity of nanoliposomal irinotecan is governed by tumor deposition and intratumor prodrug conversion. Cancer Research. 74: 7003-13
Kalra AV, Spernyak J, Kim J, et al. (2014) Abstract 2065: Magnetic resonance imaging with an iron oxide nanoparticle demonstrates the preclinical feasibility of predicting intratumoral uptake and activity of MM-398, a nanoliposomal irinotecan (nal-IRI) Cancer Research. 74: 2065-2065
Kalra A, Kim J, Klinz S, et al. (2013) Abstract 5622: The tumor microenvironment modulates the delivery and activation of liposomal encapsulated irinotecan, MM-398. Cancer Research. 73: 5622-5622
Klinz SG, Zheng J, Souza RD, et al. (2013) Abstract C293: Irinotecan sucrosofate liposome injection, MM-398, demonstrates superior activity and control of hypoxia as measured through longitudinal imaging using [18F]FAZA PET compared to free irinotecan in a colon adenocarcinoma xenograft model. Molecular Cancer Therapeutics. 12
Paz N, Laivins P, Niyikiza C, et al. (2012) Abstract A63: MM-398/PEP02, a novel liposomal formulation of irinotecan, demonstrates stromal-modifying anticancer properties. Cancer Research. 72
Kim J, Bayever E, Laivins P, et al. (2012) Abstract A6: Sustained intratumoral activation of MM-398 results in superior activity over irinotecan demonstrated by using a systems pharmacology approach Cancer Research. 72
Kalra A, Klinz S, Paz N, et al. (2012) Abstract 5696: Evaluating determinants for enhanced activity of MM-398/PEP02; a novel nanotherapeutic encapsulation of irinotecan (CPT-11) Cancer Research. 72: 5696-5696
Kim J, Saidel GM, Kalhan SC. (2011) Regulation of Adipose Tissue Metabolism in Humans: Analysis of Responses to the Hyperinsulinemic-Euglycemic Clamp Experiment. Cellular and Molecular Bioengineering. 4: 281-301
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