Courtney M. Lappas, Ph.D.

Affiliations: 
2006 University of Virginia, Charlottesville, VA 
Area:
Pharmacology, Immunology
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Joel Linden grad student 2006 UVA
 (The modulation of CD4+ T lymphocyte activity by adenosine A(2A) receptor activation.)
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Publications

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Lappas CM. (2015) The plant hormone zeatin riboside inhibits T lymphocyte activity via adenosine A2A receptor activation. Cellular & Molecular Immunology. 12: 107-12
Chehata VJ, Domeier PP, Weilnau JN, et al. (2011) Adenosine A(2A) receptor activation limits chronic granulomatous disease-induced hyperinflammation. Cellular Immunology. 267: 39-49
Lappas CM, Liu PC, Linden J, et al. (2010) Adenosine A2A receptor activation limits graft-versus-host disease after allogenic hematopoietic stem cell transplantation. Journal of Leukocyte Biology. 87: 345-54
Srinivasan S, Bolick DT, Lukashev D, et al. (2008) Sphingosine-1-phosphate reduces CD4+ T-cell activation in type 1 diabetes through regulation of hypoxia-inducible factor short isoform I.1 and CD69. Diabetes. 57: 484-93
Lappas CM, Day YJ, Marshall MA, et al. (2006) Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation. The Journal of Experimental Medicine. 203: 2639-48
Naganuma M, Wiznerowicz EB, Lappas CM, et al. (2006) Cutting edge: Critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis. Journal of Immunology (Baltimore, Md. : 1950). 177: 2765-9
Lappas CM, Sullivan GW, Linden J. (2005) Adenosine A2A agonists in development for the treatment of inflammation. Expert Opinion On Investigational Drugs. 14: 797-806
Lappas CM, Rieger JM, Linden J. (2005) A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 1073-80
Sullivan GW, Lee DD, Ross WG, et al. (2004) Activation of A2A adenosine receptors inhibits expression of alpha 4/beta 1 integrin (very late antigen-4) on stimulated human neutrophils. Journal of Leukocyte Biology. 75: 127-34
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