M Raafat El-Maghrabi
Affiliations: | Stony Brook University, Stony Brook, NY, United States |
Area:
General Biophysics, Biochemistry, Molecular BiologyGoogle:
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Publications
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| Kim SG, Cavalier M, El-Maghrabi MR, et al. (2007) A direct substrate-substrate interaction found in the kinase domain of the bifunctional enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Journal of Molecular Biology. 370: 14-26 |
| Kim SG, Manes NP, El-Maghrabi MR, et al. (2006) Crystal structure of the hypoxia-inducible form of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3): a possible new target for cancer therapy. The Journal of Biological Chemistry. 281: 2939-44 |
| Manes NP, El-Maghrabi MR. (2005) The kinase activity of human brain 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase is regulated via inhibition by phosphoenolpyruvate. Archives of Biochemistry and Biophysics. 438: 125-36 |
| El-Maghrabi M, Noto F, Wu N, et al. (2001) 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: suiting structure to need, in a family of tissue-specific enzymes. Current Opinion in Clinical Nutrition and Metabolic Care. 4: 411-418 |
| Kurland IJ, Chapman B, El-Maghrabi MR. (2000) N- and C-termini modulate the effects of pH and phosphorylation on hepatic 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Biochemical Journal. 347: 459-467 |
| Potapova IA, El-Maghrabi MR, Doronin SV, et al. (2000) Phosphorylation of recombinant human ATP:citrate lyase by cAMP-dependent protein kinase abolishes homotropic allosteric regulation of the enzyme by citrate and increases the enzyme activity. Allosteric activation of ATP:citrate lyase by phosphorylated sugars. Biochemistry. 39: 1169-79 |
| Argaud D, Lange AJ, Becker TC, et al. (1995) Adenovirus-mediated overexpression of liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in gluconeogenic rat hepatoma cells: Paradoxical effect on Fru-2,6-P2 levels Journal of Biological Chemistry. 270: 24229-24236 |
| Gidh-Jain M, Zhang Y, Poelje PDv, et al. (1995) The allosteric site of human liver fructose-1,6-bisphosphatase. Analysis of six AMP site mutants based on the crystal structure. Journal of Biological Chemistry. 269: 27732-27738 |
| Espinet C, Vargas AM, el-Maghrabi MR, et al. (1993) Expression of the liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase mRNA in FAO-1 cells. The Biochemical Journal. 293: 173-9 |
| Kurland IJ, Li L, Lange AJ, et al. (1993) Regulation of rat 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Role of the NH2-terminal region. The Journal of Biological Chemistry. 268: 14056-64 |