Kausiki Datta, Ph.D.

2004 Louisiana State University, Baton Rouge, LA, United States 
General Biophysics
"Kausiki Datta"
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Vince J. LiCata grad student 2004 Louisiana State
 (Thermodynamic characterization of DNA binding by type I DNA polymerases from Thermus aquaticus and Escherichia coli.)
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deLorimier E, Hinman MN, Copperman J, et al. (2017) Pseudouridine modification inhibits muscleblind-like 1 (MBNL1) binding to CCUG repeats and minimally structured RNA through reduced RNA flexibility. The Journal of Biological Chemistry
Roch FF, Hinterkörner G, Menke J, et al. (2015) An RNA Hybridization Assay for Screening Influenza A Virus Polymerase Inhibitors Using the Entire Ribonucleoprotein Complex. Assay and Drug Development Technologies. 13: 488-506
Datta K, Wolkerstorfer A, Szolar OH, et al. (2013) Characterization of PA-N terminal domain of Influenza A polymerase reveals sequence specific RNA cleavage. Nucleic Acids Research. 41: 8289-99
Datta K, Johnson NP, Villani G, et al. (2012) Characterization of the 6-methyl isoxanthopterin (6-MI) base analog dimer, a spectroscopic probe for monitoring guanine base conformations at specific sites in nucleic acids. Nucleic Acids Research. 40: 1191-202
Datta K, Johnson NP, von Hippel PH. (2010) DNA conformational changes at the primer-template junction regulate the fidelity of replication by DNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 107: 17980-5
Deredge DJ, Baker JT, Datta K, et al. (2010) The glutamate effect on DNA binding by pol I DNA polymerases: osmotic stress and the effective reversal of salt linkage. Journal of Molecular Biology. 401: 223-38
Wowor AJ, Datta K, Brown HS, et al. (2010) Thermodynamics of the DNA structural selectivity of the Pol I DNA polymerases from Escherichia coli and Thermus aquaticus. Biophysical Journal. 98: 3015-24
Datta K, Johnson NP, LiCata VJ, et al. (2009) Local conformations and competitive binding affinities of single- and double-stranded primer-template DNA at the polymerization and editing active sites of DNA polymerases. The Journal of Biological Chemistry. 284: 17180-93
Jose D, Datta K, Johnson NP, et al. (2009) Spectroscopic studies of position-specific DNA "breathing" fluctuations at replication forks and primer-template junctions. Proceedings of the National Academy of Sciences of the United States of America. 106: 4231-6
Deredge DJ, Thompson GS, Jiang K, et al. (2009) Klenow and Klentaq-DNA Binding: the ‘Glutamate Effect’ is Primarily an Osmotic Effect Biophysical Journal. 96: 418a-419a
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