Hassane S. Mchaourab

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
General Biophysics
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"Hassane Mchaourab"
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Children

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Jinhui Dong grad student 2005 Vanderbilt
Robel B. Yirdaw grad student 2012 Vanderbilt
P. Ryan Steed post-doc 2011-2014 Vanderbilt (Chemistry Tree)
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Publications

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Tang Q, Sinclair M, Hasdemir HS, et al. (2023) Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter. Nature Communications. 14: 7184
Tang Q, Sinclair M, Hasdemir H, et al. (2023) Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter. Biorxiv : the Preprint Server For Biology
Del Alamo D, DeSousa L, Nair RM, et al. (2022) Integrated AlphaFold2 and DEER investigation of the conformational dynamics of a pH-dependent APC antiporter. Proceedings of the National Academy of Sciences of the United States of America. 119: e2206129119
Del Alamo D, Meiler J, Mchaourab HS. (2022) Principles of Alternating Access in LeuT-fold Transporters: Commonalities and Divergences. Journal of Molecular Biology. 434: 167746
Del Alamo D, Sala D, Mchaourab HS, et al. (2022) Sampling alternative conformational states of transporters and receptors with AlphaFold2. Elife. 11
Thaker TM, Mishra S, Zhou W, et al. (2021) Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter. Nature Chemical Biology
Hustedt EJ, Stein RA, Mchaourab HS. (2021) Protein functional dynamics from the rigorous global analysis of DEER data: Conditions, components, and conformations. The Journal of General Physiology. 153
Del Alamo D, Jagessar KL, Meiler J, et al. (2021) Methodology for rigorous modeling of protein conformational changes by Rosetta using DEER distance restraints. Plos Computational Biology. 17: e1009107
Del Alamo D, Govaerts C, Mchaourab HS. (2021) AlphaFold2 predicts the inward-facing conformation of the multidrug transporter LmrP. Proteins
Castellano S, Claxton DP, Ficici E, et al. (2021) Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na in ion-coupled drug efflux. The Journal of Biological Chemistry. 296: 100262
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