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Kathrin Kirsch

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Molecular Biology, General Biophysics
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"Kathrin Kirsch"
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Gabriel Gaidos grad student 2007 Boston University
Shefali Soni grad student 2008 Boston University

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Publications

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Kumbrink J, de la Cueva A, Soni S, et al. (2016) A truncated phosphorylated p130Cas substrate domain is sufficient to drive breast cancer growth and metastasis formation in vivo. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine
Kumbrink J, de la Cueva A, Soni S, et al. (2016) A truncated phosphorylated p130Cas substrate domain is sufficient to drive breast cancer growth and metastasis formation in vivo Tumor Biology. 1-9
Rouka E, Simister PC, Janning M, et al. (2015) Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3). The Journal of Biological Chemistry. 290: 25275-92
Kumbrink J, Soni S, Laumbacher B, et al. (2015) Identification of Novel Crk-associated Substrate (p130Cas) Variants with Functionally Distinct Focal Adhesion Kinase Binding Activities. The Journal of Biological Chemistry. 290: 12247-55
Sato S, Zhao Y, Imai M, et al. (2013) Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide. Plos One. 8: e77288
Zhao Y, Kumbrink J, Lin BT, et al. (2013) Expression of a phosphorylated substrate domain of p130Cas promotes PyMT-induced c-Src-dependent murine breast cancer progression. Carcinogenesis. 34: 2880-90
Kumbrink J, Kirsch KH. (2012) Regulation of p130(Cas)/BCAR1 expression in tamoxifen-sensitive and tamoxifen-resistant breast cancer cells by EGR1 and NAB2. Neoplasia (New York, N.Y.). 14: 108-20
Sato S, Trackman PC, Mäki JM, et al. (2011) The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells. Molecular and Cellular Biology. 31: 2683-95
Min C, Zhao Y, Romagnoli M, et al. (2010) Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis. Journal of Cellular Biochemistry. 111: 1160-8
Min C, Yu Z, Kirsch KH, et al. (2009) A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer. Cancer Research. 69: 6685-93
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