Lawreen H. Connors

Affiliations: 
Boston University, Boston, MA, United States 
Area:
General Biophysics
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"Lawreen Connors"
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Publications

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Klimtchuk ES, Peterle D, Bullitt EA, et al. (2023) Role of Complementarity-Determining Regions 1 and 3 in Pathologic Amyloid Formation by Human Immunoglobulin κ1 Light Chains. Biorxiv : the Preprint Server For Biology
Mendelson L, Sanchorawala V, Connors L, et al. (2022) Correlation Between 24-Hour Urine Protein and Random Urine Protein-Creatinine Ratio in Amyloid Light-Chain Amyloidosis. Kidney Medicine. 4: 100427
Peterle D, Klimtchuk ES, Wales TE, et al. (2021) A conservative point mutation in a dynamic antigen-binding loop of human immunoglobulin λ6 light chain promotes pathologic amyloid formation. Journal of Molecular Biology. 167310
Torres-Arancivia CM, Chang D, Hackett WE, et al. (2020) Glycosylation of Serum Clusterin in Wild-Type Transthyretin-Associated (ATTRwt) Amyloidosis: A Study of Disease-Associated Compositional Features Using Mass Spectrometry Analyses. Biochemistry
Giadone RM, Liberti DC, Matte TM, et al. (2020) Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease. Stem Cell Reports
Schulman A, Connors LH, Weinberg J, et al. (2020) Patient Outcomes in Light Chain (AL) amyloidosis: the Clock is Ticking from Symptoms to Diagnosis. European Journal of Haematology
Dasari AKR, Hung I, Michael B, et al. (2020) Structural Characterization of Cardiac ex vivo Transthyretin Amyloid: Insight into Transthyretin Misfolding Pathway in vivo. Biochemistry
Fu J, Bhatt N, Kim J, et al. (2019) Real-Time PET Imaging with Amyloid Fibril-Reactive Antibody CAEL-101 for Personalized AL Amyloidosis Immunotherapy Clinical Lymphoma Myeloma and Leukemia. 19: e314
Klimtchuk ES, Prokaeva T, Frame NM, et al. (2018) Unusual duplication mutation in a surface loop of human transthyretin leads to an aggressive drug-resistant amyloid disease. Proceedings of the National Academy of Sciences of the United States of America
Mints YY, Doros G, Berk JL, et al. (2018) Features of atrial fibrillation in wild-type transthyretin cardiac amyloidosis: a systematic review and clinical experience. Esc Heart Failure
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