Anant Chopra, Ph.D.

Affiliations: 
2009-2012 Drexel University, Philadelphia, PA, United States 
 2013-2018 Biomedical Engineering Boston University & Harvard Medical School 
 2019- Bayer, Plano, TX, United States 
Area:
Biomedical Engineering
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"Anant Chopra"
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Parents

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J Yasha Kresh grad student 2012 Drexel
 (Intercellular and extracellular adhesion signals control cardiac myocyte structural and functional remodeling: mechanosensing mediated by cadherin and hyaluronan receptors.)
Paul A. Janmey grad student 2009-2012 (Chemistry Tree)
Christopher S. Chen post-doc (BME Tree)
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Publications

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Toepfer CN, Garfinkel AC, Venturini G, et al. (2020) Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy. Circulation
Chopra A, Kutys ML, Zhang K, et al. (2018) Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions. Developmental Cell. 44: 87-96.e5
Hinson JT, Chopra A, Lowe A, et al. (2017) Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. Cell Reports. 19: 2410
Hinson JT, Chopra A, Lowe A, et al. (2016) Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. Cell Reports. 17: 3292-3304
Keung W, Ren L, Sen Li, et al. (2016) Non-cell autonomous cues for enhanced functionality of human embryonic stem cell-derived cardiomyocytes via maturation of sarcolemmal and mitochondrial KATP channels. Scientific Reports. 6: 34154
Hinson JT, Chopra A, Nafissi N, et al. (2015) HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy. Science (New York, N.Y.). 349: 982-6
Poon E, Keung W, Liang Y, et al. (2015) Proteomic Analysis of Human Pluripotent Stem Cell-Derived, Fetal, and Adult Ventricular Cardiomyocytes Reveals Pathways Crucial for Cardiac Metabolism and Maturation. Circulation. Cardiovascular Genetics. 8: 427-36
Chen G, Li S, Karakikes I, et al. (2015) Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs. Circulation. Arrhythmia and Electrophysiology. 8: 193-202
Stapleton SC, Chopra A, Chen CS. (2014) Force measurement tools to explore cadherin mechanotransduction. Cell Communication & Adhesion. 21: 193-205
Chopra A, Murray ME, Byfield FJ, et al. (2014) Augmentation of integrin-mediated mechanotransduction by hyaluronic acid. Biomaterials. 35: 71-82
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