Shannon E. Telesco, Ph.D.
Affiliations: | 2011 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Biomedical Engineering, Oncology, Molecular BiologyGoogle:
"Shannon Telesco"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Ravi Radhakrishnan | grad student | 2011 | Penn | |
| (Multiscale modeling of the ErbB receptor tyrosine kinase signaling network through theory and experiment.) | ||||
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Publications
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| Telesco SE, Vadigepalli R, Radhakrishnan R. (2013) Molecular modeling of ErbB4/HER4 kinase in the context of the HER4 signaling network helps rationalize the effects of clinically identified HER4 somatic mutations on the cell phenotype. Biotechnology Journal. 8: 1452-64 |
| Telesco SE, Radhakrishnan R. (2012) Structural systems biology and multiscale signaling models. Annals of Biomedical Engineering. 40: 2295-306 |
| Telesco SE, Shih A, Liu Y, et al. (2011) Investigating Molecular Mechanisms of Activation and Mutation of the HER2 Receptor Tyrosine Kinase through Computational Modeling and Simulation. Cancer Research Journal. 4: 1-35 |
| Shih AJ, Telesco SE, Radhakrishnan R. (2011) Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases. Cancers. 3: 1195-231 |
| Telesco SE, Shih AJ, Jia F, et al. (2011) A multiscale modeling approach to investigate molecular mechanisms of pseudokinase activation and drug resistance in the HER3/ErbB3 receptor tyrosine kinase signaling network. Molecular Biosystems. 7: 2066-80 |
| Shih AJ, Telesco SE, Choi SH, et al. (2011) Molecular dynamics analysis of conserved hydrophobic and hydrophilic bond-interaction networks in ErbB family kinases. The Biochemical Journal. 436: 241-51 |
| Shi F, Telesco SE, Liu Y, et al. (2010) ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 107: 7692-7 |
| Shih AJ, Telesco SE, Choi SH, et al. (2010) Conserved Hydrophobic and Hydrophilic Bond Interaction Networks in ErbB Family Kinases Biophysical Journal. 98: 445a |
| Telesco SE, Radhakrishnan R. (2009) Atomistic insights into regulatory mechanisms of the HER2 tyrosine kinase domain: a molecular dynamics study. Biophysical Journal. 96: 2321-34 |