Penxiang Huang, Ph.D.

Affiliations: 
2009 University of Virginia, Charlottesville, VA 
Area:
General Biophysics, Biochemistry, Cell Biology
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"Penxiang Huang"
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Parents

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Fraydon Rastinejad grad student 2009 UVA
 (Structure-Function Studies of Nuclear Receptors.)
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Publications

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Santori FR, Huang P, van de Pavert SA, et al. (2015) Identification of natural RORγ ligands that regulate the development of lymphoid cells. Cell Metabolism. 21: 286-97
Huang P, Chandra V, Rastinejad F. (2014) Retinoic acid actions through mammalian nuclear receptors. Chemical Reviews. 114: 233-54
Rastinejad F, Huang P, Chandra V, et al. (2013) Understanding nuclear receptor form and function using structural biology. Journal of Molecular Endocrinology. 51: T1-T21
Huh JR, Englund EE, Wang H, et al. (2013) Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors. Acs Medicinal Chemistry Letters. 4: 79-84
Chandra V, Huang P, Potluri N, et al. (2013) Multidomain integration in the structure of the HNF-4α nuclear receptor complex. Nature. 495: 394-8
Huh JR, Leung MW, Huang P, et al. (2011) Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity. Nature. 472: 486-90
Kim D, Blus BJ, Chandra V, et al. (2010) Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain. Nature Structural & Molecular Biology. 17: 1027-9
Huang P, Chandra V, Rastinejad F. (2010) Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics. Annual Review of Physiology. 72: 247-72
Chandra V, Huang P, Hamuro Y, et al. (2008) Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature. 456: 350-6
Raghuram S, Stayrook KR, Huang P, et al. (2007) Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta. Nature Structural & Molecular Biology. 14: 1207-13
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