Omar Zgheib, Ph.D.

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology
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"Omar Zgheib"
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Thanos D. Halazonetis grad student 2007 Penn
 (Mechanism of recruitment of p53-binding protein 1 (53BP1) to DNA double-strand breaks.)
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Publications

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Ricciardiello R, Forleo G, Cipolla L, et al. (2024) Homozygous substitution of threonine 191 by proline in polymerase η causes Xeroderma pigmentosum variant. Scientific Reports. 14: 1117
Crefcoeur RP, Zgheib O, Halazonetis TD. (2017) A Model to Investigate Single-Strand DNA Responses in G1 Human Cells via a Telomere-Targeted, Nuclease-Deficient CRISPR-Cas9 System. Plos One. 12: e0169126
Pataky K, Villanueva G, Liani A, et al. (2009) Microcollimator for micrometer-wide stripe irradiation of cells using 20-30 keV X rays. Radiation Research. 172: 252-9
Zgheib O, Pataky K, Brugger J, et al. (2009) An oligomerized 53BP1 tudor domain suffices for recognition of DNA double-strand breaks. Molecular and Cellular Biology. 29: 1050-8
Venere M, Snyder A, Zgheib O, et al. (2007) Phosphorylation of ATR-interacting protein on Ser239 mediates an interaction with breast-ovarian cancer susceptibility 1 and checkpoint function. Cancer Research. 67: 6100-5
Grenon M, Costelloe T, Jimeno S, et al. (2007) Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain. Yeast (Chichester, England). 24: 105-19
Zgheib O, Huyen Y, DiTullio RA, et al. (2005) ATM signaling and 53BP1. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 76: 119-22
Huyen Y, Zgheib O, Ditullio RA, et al. (2004) Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature. 432: 406-11
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