Roger K. Sunahara

Affiliations: 
Chemical Biology University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
General, General Biophysics, Pharmacology
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"Roger Sunahara"
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Publications

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Xu X, Shonberg J, Kaindl J, et al. (2023) Constrained catecholamines gain βAR selectivity through allosteric effects on pocket dynamics. Nature Communications. 14: 2138
Huang SK, Picard LP, Rahmatullah RSM, et al. (2023) Mapping the conformational landscape of the stimulatory heterotrimeric G protein. Nature Structural & Molecular Biology
Huang SK, Pandey A, Tran DP, et al. (2021) Delineating the conformational landscape of the adenosine A receptor during G protein coupling. Cell
Maeda S, Xu J, N Kadji FM, et al. (2020) Structure and selectivity engineering of the M muscarinic receptor toxin complex. Science (New York, N.Y.). 369: 161-167
Yin J, Chen KM, Clark MJ, et al. (2020) Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane. Nature
Liu X, Kaindl J, Korczynska M, et al. (2020) An allosteric modulator binds to a conformational hub in the β adrenergic receptor. Nature Chemical Biology
Nguyen AH, Thomsen ARB, Cahill TJ, et al. (2019) Structure of an endosomal signaling GPCR-G protein-β-arrestin megacomplex. Nature Structural & Molecular Biology
Glukhova A, Draper-Joyce CJ, Sunahara RK, et al. (2018) Rules of Engagement: GPCRs and G Proteins. Acs Pharmacology & Translational Science. 1: 73-83
Liu H, Hofmann J, Fish I, et al. (2018) Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists. Proceedings of the National Academy of Sciences of the United States of America
Masureel M, Zou Y, Picard LP, et al. (2018) Structural insights into binding specificity, efficacy and bias of a βAR partial agonist. Nature Chemical Biology. 14: 1059-1066
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