Richard C. Boucher

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Molecular Biology
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"Richard Boucher"

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Lauranell H. Burch grad student 2001 UNC Chapel Hill
Liheng Cai post-doc UNC Chapel Hill (Physics Tree)
Larry G Johnson research scientist
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Publications

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Wang S, Niroula S, Hoffman A, et al. (2023) Inflammatory Activity of Epithelial Stem Cell Variants from Cystic Fibrosis Lung Is Not Resolved by CFTR Modulators. American Journal of Respiratory and Critical Care Medicine
Mikami Y, Grubb BR, Rogers TD, et al. (2023) Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration. Science Translational Medicine. 15: eabo7728
Batson B, Zorn B, Radicioni G, et al. (2022) Cystic Fibrosis Airway Mucus Hyperconcentration Produces a Vicious Cycle of Mucin, Pathogen, and Inflammatory Interactions that Promote Disease Persistence. American Journal of Respiratory Cell and Molecular Biology
Markovetz MR, Garbarine IC, Morrison CB, et al. (2022) Mucus and mucus flake composition and abundance reflect inflammatory and infection status in cystic fibrosis. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Kato T, Radicioni G, Papanikolas MJ, et al. (2022) Mucus concentration-dependent biophysical abnormalities unify submucosal gland and superficial airway dysfunction in cystic fibrosis. Science Advances. 8: eabm9718
Singanayagam A, Footitt J, Marczynski M, et al. (2022) Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease. The Journal of Clinical Investigation
Hill DB, Button B, Rubinstein M, et al. (2022) Physiology and Pathophysiology of Human Airway Mucus. Physiological Reviews
Lazarowski ER, Boucher RC. (2020) Purinergic receptors in airway hydration. Biochemical Pharmacology. 114387
Okuda K, Dang H, Kobayashi Y, et al. (2020) Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia. American Journal of Respiratory and Critical Care Medicine
Xu J, Livraghi-Butrico A, Hou X, et al. (2020) Phenotypes of CF rabbits generated by CRISPR/Cas9-mediated disruption of the CFTR gene. Jci Insight
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