Matthew P. Jacobson
Affiliations: | 2002- | Pharmaceutical Chemistry | University of California, San Francisco, San Francisco, CA |
Area:
computational structural biology, computer-aided drug designWebsite:
https://pharmacy.ucsf.edu/matt-jacobsonGoogle:
"Matthew Paul Jacobson" OR "Matthew P Jacobson" OR "Matt Jacobson"Bio:
https://profiles.ucsf.edu/matthew.jacobson
https://jacobsonlab.wordpress.com/about/biosketch/
Jacobson, Matthew Paul, Spectroscopic patterns encode unimolecular dynamics Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1999.
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Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Robert W. Field | grad student | 1999 | MIT (Chemistry Tree) | |
| (Spectroscopic patterns encode unimolecular dynamics) | ||||
| Robert J. Silbey | grad student | 1999 | MIT (Chemistry Tree) | |
| Mark S. Child | post-doc | Oxford (Chemistry Tree) | ||
Children
Sign in to add trainee| Katherine A. Ball | grad student | ||
| Sergio E. Wong | grad student | 2006 | UCSF (Chemistry Tree) |
| Jerome P. Nilmeier | grad student | 2008 | UCSF (Chemistry Tree) |
| Benjamin D. Sellers | grad student | 2008 | UCSF (Chemistry Tree) |
| Monica Tremont | grad student | 2013 | UCSF (Chemistry Tree) |
| Niu Huang | post-doc | (Chemistry Tree) | |
| Lan Hua | post-doc | 2011-2012 | UCSF (Chemistry Tree) |
| Ryan Pemberton | post-doc | 2015-2016 | UCSF (Chemistry Tree) |
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Publications
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| Fink EA, Xu J, Hübner H, et al. (2022) Structure-based discovery of nonopioid analgesics acting through the α-adrenergic receptor. Science (New York, N.Y.). 377: eabn7065 |
| Lak P, O'Donnell H, Du X, et al. (2021) A Crowding Barrier to Protein Inhibition in Colloidal Aggregates. Journal of Medicinal Chemistry |
| Gordon DE, Jang GM, Bouhaddou M, et al. (2020) A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature |
| Ali I, Ruiz DG, Ni Z, et al. (2019) Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins. Molecular Cell |
| Ball KA, Chan LM, Stanley DJ, et al. (2019) Conformational Dynamics of the HIV-Vif Protein Complex. Biophysical Journal |
| Aleem A, Tsai WC, Tena J, et al. (2018) Probing the Electrostatic and Steric Requirements for Substrate Binding in Human Platelet-type 12-Lipoxygenase. Biochemistry |
| Tang S, Zhang N, Zhou Y, et al. (2018) Structure-Based Discovery of Novel CK2α-Binding Cyclic Peptides with Anti-Cancer Activity. Molecular Informatics |
| Shao H, Li X, Moses MA, et al. (2018) Exploration of Benzothiazole-Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70). Journal of Medicinal Chemistry |
| Taylor IR, Dunyak BM, Komiyama T, et al. (2018) High Throughput Screen for Inhibitors of Protein-Protein Interactions in a Reconstituted Heat Shock Protein 70 (Hsp70) Complex. The Journal of Biological Chemistry |
| Calhoun S, Korczynska M, Wichelecki DJ, et al. (2018) Prediction of enzymatic pathways by integrative pathway mapping. Elife. 7 |