Patrice Dubreuil

Affiliations: 
INSERM, Rennes, Bretagne, France 
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"Patrice Dubreuil"
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Weisberg E, Meng C, Case AE, et al. (2019) Comparison of effects of midostaurin, crenolanib, quizartinib, gilteritinib, sorafenib and BLU-285 on oncogenic mutants of KIT, CBL and FLT3 in haematological malignancies. British Journal of Haematology
Martinez-Anton A, Gras D, Bourdin A, et al. (2018) KIT as a therapeutic target for non-oncological diseases. Pharmacology & Therapeutics
Janovec V, Aouar B, Font-Haro A, et al. (2018) The MEK1/2-ERK Pathway Inhibits Type I IFN Production in Plasmacytoid Dendritic Cells. Frontiers in Immunology. 9: 364
Malbec O, Cassard L, Albanesi M, et al. (2016) Trans-inhibition of activation and proliferation signals by Fc receptors in mast cells and basophils. Science Signaling. 9: ra126
Lopez S, Voisset E, Tisserand JC, et al. (2016) An essential pathway links FLT3-ITD, HCK and CDK6 in acute myeloid leukemia. Oncotarget
Chaix A, Arcangeli ML, Lopez S, et al. (2014) KIT-D816V oncogenic activity is controlled by the juxtamembrane docking site Y568-Y570 Oncogene. 33: 872-881
D'allard D, Gay J, Descarpentries C, et al. (2013) Tyrosine kinase inhibitors induce down-regulation of c-Kit by targeting the ATP pocket. Plos One. 8: e60961
Georgin-Lavialle S, Lhermitte L, Suarez F, et al. (2012) Mast cell leukemia: identification of a new c-Kit mutation, dup(501-502), and response to masitinib, a c-Kit tyrosine kinase inhibitor. European Journal of Haematology. 89: 47-52
Chaix A, Lopez S, Voisset E, et al. (2011) Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells Journal of Biological Chemistry. 286: 5956-5966
Voisset E, Lopez S, Dubreuil P, et al. (2007) The tyrosine kinase FES is an essential effector of KITD816V proliferation signal Blood. 110: 2593-2599
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