Aaron T. Jacobs, Ph.D. - Publications

Institution:
University of California, Los Angeles, Los Angeles, CA
Area:
regulation and modulation of nitric oxide (NO) production and cytotoxicity in macrophages, vascular cells, and tumor cells

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Siraj MA, Jacobs AT, Tan GT. Altersolanol B, a fungal tetrahydroanthraquinone, inhibits the proliferation of estrogen receptor-expressing (ER+) human breast adenocarcinoma by modulating PI3K/AKT, p38/ERK MAPK and associated signaling pathways. Chemico-Biological Interactions. 359: 109916. PMID 35346647 DOI: 10.1016/j.cbi.2022.109916  0.314
2017 Connelly L, Yadav N, Barcikowski A, Imaizumi Y, Jacobs A. Abstract P4-03-13: Obesity and breast cancer: The adipocyte-macrophage interaction as a mediator of metastasis Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P4-03-13  0.342
2016 Pinner KD, Wales CT, Gristock RA, Vo HT, So N, Jacobs AT. Flavokawains A and B from kava (Piper methysticum) activate heat shock and antioxidant responses and protect against hydrogen peroxide-induced cell death in HepG2 hepatocytes. Pharmaceutical Biology. 1-10. PMID 26789234 DOI: 10.3109/13880209.2015.1107104  0.405
2015 Wales CT, Taylor FR, Higa AT, McAllister HA, Jacobs AT. ERK-dependent phosphorylation of HSF1 mediates chemotherapeutic resistance to benzimidazole carbamates in colorectal cancer cells. Anti-Cancer Drugs. 26: 657-66. PMID 25811962 DOI: 10.1097/Cad.0000000000000231  0.383
2015 Wales CT, Gristock R, So N, Jacobs AT. Abstract 1246: c-Myc is critical for apoptosis in 4-hyroxynonenal-treated colorectal cancer cells Cancer Research. 75: 1246-1246. DOI: 10.1158/1538-7445.Am2015-1246  0.373
2014 Samarasinghe B, Wales CT, Taylor FR, Jacobs AT. Heat shock factor 1 confers resistance to Hsp90 inhibitors through p62/SQSTM1 expression and promotion of autophagic flux. Biochemical Pharmacology. 87: 445-55. PMID 24291777 DOI: 10.1016/J.Bcp.2013.11.014  0.367
2014 Wales CTK, Jacobs AT. Abstract 681: Heat shock-mediated suppression of ODC protein expression in colorectal cancer cells Cancer Research. 74: 681-681. DOI: 10.1158/1538-7445.Am2014-681  0.389
2014 Cusick JK, Sumida C, Checketts M, Reyland ME, Jacobs AT. Abstract 2264: HIC (MDFIC) is a protein that interacts and colocalizes with the RELT family of TNFRs Cancer Research. 74: 2264-2264. DOI: 10.1158/1538-7445.Am2014-2264  0.345
2014 Yadav NVS, Jacobs AT, Connelly L. Abstract 1096: Investigating the role of the adipocyte-macrophage interaction in breast cancer metastasis Cancer Research. 74: 1096-1096. DOI: 10.1158/1538-7445.Am2014-1096  0.341
2013 Wales CTK, Jacobs AT. Abstract 763: Hyperthermia promotes c-myc turnover and reduces ODC expression in colorectal cancer cells. Cancer Research. 73: 763-763. DOI: 10.1158/1538-7445.Am2013-763  0.385
2012 Cusick JK, Mustian A, Jacobs AT, Reyland ME. Identification of PLSCR1 as a protein that interacts with RELT family members. Molecular and Cellular Biochemistry. 362: 55-63. PMID 22052202 DOI: 10.1007/S11010-011-1127-4  0.31
2012 Samarasinghe BN, Wales CT, Jacobs AT. Abstract 2261: Heat-shock and autophagy in cancer: Novel role for DGK iota Cancer Research. 72: 2261-2261. DOI: 10.1158/1538-7445.Am2012-2261  0.427
2010 Jacobs AT, Marnett LJ. Systems analysis of protein modification and cellular responses induced by electrophile stress. Accounts of Chemical Research. 43: 673-83. PMID 20218676 DOI: 10.1021/Ar900286Y  0.407
2010 Marnett LJ, Jacobs A, Vila A, McGrath C, Boiani M, Ullery J, Tallman K, Porter NA, Zhang B, Liebler DC. Systems Approaches to Establishing the Relationship Between Protein Modification and Cellular Responses by Lipid Electrophiles Free Radical Biology and Medicine. 49: S8. DOI: 10.1016/J.Freeradbiomed.2010.10.677  0.433
2009 Jacobs AT, Marnett LJ. HSF1-mediated BAG3 expression attenuates apoptosis in 4-hydroxynonenal-treated colon cancer cells via stabilization of anti-apoptotic Bcl-2 proteins. The Journal of Biological Chemistry. 284: 9176-83. PMID 19179333 DOI: 10.1074/Jbc.M808656200  0.404
2008 Vila A, Tallman KA, Jacobs AT, Liebler DC, Porter NA, Marnett LJ. Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives. Chemical Research in Toxicology. 21: 432-44. PMID 18232660 DOI: 10.1021/Tx700347W  0.373
2007 Jacobs AT, Marnett LJ. Heat shock factor 1 attenuates 4-Hydroxynonenal-mediated apoptosis: critical role for heat shock protein 70 induction and stabilization of Bcl-XL. The Journal of Biological Chemistry. 282: 33412-20. PMID 17873279 DOI: 10.1074/Jbc.M706799200  0.394
2005 Rouzer CA, Jacobs AT, Nirodi CS, Kingsley PJ, Morrow JD, Marnett LJ. RAW264.7 cells lack prostaglandin-dependent autoregulation of tumor necrosis factor-alpha secretion. Journal of Lipid Research. 46: 1027-37. PMID 15722559 DOI: 10.1194/Jlr.M500006-Jlr200  0.389
2003 Jacobs AT, Ignarro LJ. Cell density-enhanced expression of inducible nitric oxide synthase in murine macrophages mediated by interferon-beta. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 8: 222-30. PMID 12895431 DOI: 10.1016/S1089-8603(03)00027-2  0.592
2003 Connelly L, Jacobs AT, Palacios-Callender M, Moncada S, Hobbs AJ. Macrophage endothelial nitric-oxide synthase autoregulates cellular activation and pro-inflammatory protein expression. The Journal of Biological Chemistry. 278: 26480-7. PMID 12740377 DOI: 10.1074/Jbc.M302238200  0.459
2003 Sumi D, Hayashi T, Matsui-Hirai H, Jacobs AT, Ignarro LJ, Iguchi A. 17beta-estradiol inhibits NADPH oxidase activity through the regulation of p47phox mRNA and protein expression in THP-1 cells. Biochimica Et Biophysica Acta. 1640: 113-8. PMID 12729920 DOI: 10.1016/S0167-4889(03)00026-0  0.568
2003 Jacobs AT, Ignarro LJ. Nuclear factor-kappa B and mitogen-activated protein kinases mediate nitric oxide-enhanced transcriptional expression of interferon-beta. The Journal of Biological Chemistry. 278: 8018-27. PMID 12500976 DOI: 10.1074/Jbc.M211642200  0.579
2001 Jacobs AT, Ignarro LJ. Lipopolysaccharide-induced expression of interferon-beta mediates the timing of inducible nitric-oxide synthase induction in RAW 264.7 macrophages. The Journal of Biological Chemistry. 276: 47950-7. PMID 11602590 DOI: 10.1074/Jbc.M106639200  0.582
2000 Wei LH, Jacobs AT, Morris SM, Ignarro LJ. IL-4 and IL-13 upregulate arginase I expression by cAMP and JAK/STAT6 pathways in vascular smooth muscle cells. American Journal of Physiology. Cell Physiology. 279: C248-56. PMID 10898736 DOI: 10.1152/Ajpcell.2000.279.1.C248  0.494
2000 Ignarro LJ, Jacobs A. Chapter 1 Nitric oxide synthase and the production of nitric oxide Handbook of Chemical Neuroanatomy. 17: 1-17. DOI: 10.1016/S0924-8196(00)80055-X  0.414
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