| Year |
Citation |
Score |
| 2020 |
Chen S, Wang T, Yao J, Brinton RD. Allopregnanolone Promotes Neuronal and Oligodendrocyte Differentiation In Vitro and In Vivo: Therapeutic Implication for Alzheimer's Disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 32632771 DOI: 10.1007/S13311-020-00874-X |
0.584 |
|
| 2019 |
Wang T, Yao J, Chen S, Mao Z, Brinton RD. Allopregnanolone Reverses Bioenergetic Deficits in Female Triple Transgenic Alzheimer's Mouse Model. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 31664643 DOI: 10.1007/S13311-019-00793-6 |
0.684 |
|
| 2019 |
Chen S, Yao J, Wang T, Brinton RD. P3-060: ALLOPREGNANOLONE REVERSED OVARIECTOMY-INDUCED BIOENERGETIC DEFICITS IN FEMALE TRIPLE TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P948-P949. DOI: 10.1016/J.Jalz.2019.06.3087 |
0.593 |
|
| 2017 |
Yin F, Yao J, Brinton RD, Cadenas E. Editorial: The Metabolic-Inflammatory Axis in Brain Aging and Neurodegeneration. Frontiers in Aging Neuroscience. 9: 209. PMID 28701949 DOI: 10.3389/Fnagi.2017.00209 |
0.588 |
|
| 2017 |
Mao Z, Yin F, Yao J, Diaz Brinton R. [P2-188]: FEMALE BRAIN BIOENERGETIC SYSTEM IS REGULATED BY ENDOCRINE AGING: IMPLICATIONS FOR ALZHEIMER'S DISEASE Alzheimer's & Dementia. 13: P678-P678. DOI: 10.1016/J.Jalz.2017.06.839 |
0.484 |
|
| 2017 |
Chen S, Yao J, Wong K, Diaz Brinton R. [P2-180]: IMPACT OF ALLOPREGNANOLONE ON NEURAL DIFFERENTIATION: DEVELOPMENT OF A REGENERATIVE THERAPEUTIC FOR ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P675-P675. DOI: 10.1016/J.Jalz.2017.06.831 |
0.365 |
|
| 2016 |
Zhang L, Trushin S, Christensen TA, Bachmeier BV, Gateno B, Schroeder A, Yao J, Itoh K, Sesaki H, Poon WW, Gylys KH, Patterson ER, Parisi JE, Diaz Brinton R, Salisbury JL, et al. Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease. Scientific Reports. 6: 18725. PMID 26729583 DOI: 10.1038/Srep18725 |
0.528 |
|
| 2016 |
Klosinski L, Yao J, Fonteh A, Harrington M, Christensen T, Trushina E, Brinton RD. P2-117: Perimenopause in APOE4 Brain: Accelerated Myelin Catabolism for Fuel Alzheimer's & Dementia. 12: P656-P657. DOI: 10.1016/J.Jalz.2016.06.1487 |
0.558 |
|
| 2015 |
Klosinski LP, Yao J, Yin F, Fonteh AN, Harrington MG, Christensen TA, Trushina E, Brinton RD. White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease. Ebiomedicine. 2: 1888-904. PMID 26844268 DOI: 10.1016/J.Ebiom.2015.11.002 |
0.67 |
|
| 2015 |
Brinton RD, Yao J, Yin F, Mack WJ, Cadenas E. Perimenopause as a neurological transition state. Nature Reviews. Endocrinology. 11: 393-405. PMID 26007613 DOI: 10.1038/Nrendo.2015.82 |
0.581 |
|
| 2015 |
Yin F, Yao J, Sancheti H, Feng T, Melcangi RC, Morgan TE, Finch CE, Pike CJ, Mack WJ, Cadenas E, Brinton RD. The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity. Neurobiology of Aging. 36: 2282-95. PMID 25921624 DOI: 10.1016/J.Neurobiolaging.2015.03.013 |
0.643 |
|
| 2015 |
Caldwell CC, Yao J, Brinton RD. Targeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunities. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 66-80. PMID 25534394 DOI: 10.1007/S13311-014-0324-8 |
0.637 |
|
| 2015 |
Klosinski L, Yao J, Chen S, Mao J, Trushina E, Tiwari-Woodruff S, Diaz-Brinton R. Mechanistic pathways linking mitochondrial oxidative stress and white matter degeneration in the aging mammalian female brain Alzheimers & Dementia. 11: 630. DOI: 10.1016/J.Jalz.2015.06.894 |
0.438 |
|
| 2015 |
Yin F, Yao J, Sancheti H, Feng T, Mack WJ, Cadenas E, Diaz-Brinton R. P1-072: Aging transition of perimenopause is associated with bioenergetic shift in the female brain and decline in long-term potentiation Alzheimer's & Dementia. 11: P365-P366. DOI: 10.1016/J.Jalz.2015.06.269 |
0.365 |
|
| 2015 |
Klosinski LP, Yao J, Yin F, Fonteh AN, Harrington MG, Christensen TA, Trushina E, Brinton RD. White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease Ebiomedicine. DOI: 10.1016/j.ebiom.2015.11.002 |
0.565 |
|
| 2014 |
Rettberg JR, Yao J, Brinton RD. Estrogen: a master regulator of bioenergetic systems in the brain and body. Frontiers in Neuroendocrinology. 35: 8-30. PMID 23994581 DOI: 10.1016/J.Yfrne.2013.08.001 |
0.802 |
|
| 2014 |
Brinton RD, Zhao L, Yin F, Yao J, Cadenas E. P1-101: SEX DIFFERENCES IN BIOENERGETIC AGING OF THE BRAIN AND RISK OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P339-P339. DOI: 10.1016/J.Jalz.2014.05.338 |
0.622 |
|
| 2013 |
Ding F, Yao J, Rettberg JR, Chen S, Brinton RD. Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention. Plos One. 8: e79977. PMID 24244584 DOI: 10.1371/Journal.Pone.0079977 |
0.796 |
|
| 2013 |
Jiang T, Yin F, Yao J, Brinton RD, Cadenas E. Lipoic acid restores age-associated impairment of brain energy metabolism through the modulation of Akt/JNK signaling and PGC1α transcriptional pathway. Aging Cell. 12: 1021-31. PMID 23815272 DOI: 10.1111/Acel.12127 |
0.63 |
|
| 2013 |
Ding F, Yao J, Zhao L, Mao Z, Chen S, Brinton RD. Ovariectomy induces a shift in fuel availability and metabolism in the hippocampus of the female transgenic model of familial Alzheimer's. Plos One. 8: e59825. PMID 23555795 DOI: 10.1371/Journal.Pone.0059825 |
0.716 |
|
| 2013 |
Yao J, Zhao L, Mao Z, Chen S, Wong KC, To J, Brinton RD. Potentiation of brain mitochondrial function by S-equol and R/S-equol estrogen receptor β-selective phytoSERM treatments. Brain Research. 1514: 128-41. PMID 23428542 DOI: 10.1016/J.Brainres.2013.02.021 |
0.647 |
|
| 2013 |
Zhao L, Yao J, Ding F, Chen S, Klosinski L, Rettberg J, Brinton R. P2-011: A bioenergetic trajectory of female brain aging and Alzheimer's disease 1: Implications for risk prevention and treatment Alzheimer's & Dementia. 9: P349-P349. DOI: 10.1016/J.Jalz.2013.05.653 |
0.766 |
|
| 2013 |
Klosinski L, Yao J, Chen S, Mao Z, Zhao L, Brinton R. P2-008: A bioenergetic trajectory of female brain aging and Alzheimer's disease 2: Mechanistic link between mitochondrial dysfunction and white matter degeneration in the normal mammalian aging female brain Alzheimer's & Dementia. 9: P348-P348. DOI: 10.1016/J.Jalz.2013.05.650 |
0.663 |
|
| 2013 |
Irwin R, Chen S, To J, Zhu M, Yao J, Rodgers K, Bolger M, Brinton R. P4-016: Allopregnanolone as a regenerative therapeutic for Alzheimer's disease, 2: Bridging subcutaneous to intravenous formulations for clinical trials Alzheimer's & Dementia. 9: P710-P711. DOI: 10.1016/J.Jalz.2013.05.1404 |
0.7 |
|
| 2013 |
Chen S, Yao J, Wong K, Brinton R. P4-014: Allopregnanolone as a regenerative therapeutic for Alzheimer's disease, 4: Impact on neuronal versus gliosis phenotypic differentiation Alzheimer's & Dementia. 9: P710-P710. DOI: 10.1016/J.Jalz.2013.05.1402 |
0.652 |
|
| 2013 |
Yao J, Chen S, Wong K, Irwin R, Brinton R. P4-013: Allopregnanolone as a regenerative therapeutic for Alzheimer's disease, 3: Evidence for potentiation of brain mitochondrial function Alzheimer's & Dementia. 9: P709-P710. DOI: 10.1016/J.Jalz.2013.05.1401 |
0.781 |
|
| 2012 |
Yao J, Brinton RD. Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease. Advances in Pharmacology (San Diego, Calif.). 64: 327-71. PMID 22840752 DOI: 10.1016/B978-0-12-394816-8.00010-6 |
0.665 |
|
| 2012 |
Irwin RW, Yao J, To J, Hamilton RT, Cadenas E, Brinton RD. Selective oestrogen receptor modulators differentially potentiate brain mitochondrial function. Journal of Neuroendocrinology. 24: 236-48. PMID 22070562 DOI: 10.1111/J.1365-2826.2011.02251.X |
0.751 |
|
| 2012 |
Singh C, Liu L, Wang JM, Irwin RW, Yao J, Chen S, Henry S, Thompson RF, Brinton RD. Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice. Neurobiology of Aging. 33: 1493-506. PMID 21803451 DOI: 10.1016/J.Neurobiolaging.2011.06.008 |
0.762 |
|
| 2012 |
Yao J, Irwin R, Chen S, Hamilton R, Cadenas E, Brinton RD. Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid. Neurobiology of Aging. 33: 1507-21. PMID 21514693 DOI: 10.1016/J.Neurobiolaging.2011.03.001 |
0.777 |
|
| 2012 |
Mao Z, Zhao L, Yao J, Ding F, Cadenas E, Brinton R. P2-129: Effects of age and reproductive status on gene expression in the female hippocampus Alzheimer's & Dementia. 8: P305-P305. DOI: 10.1016/J.Jalz.2012.05.834 |
0.628 |
|
| 2012 |
Ding F, Luo J, Yao J, Mao Z, Chen S, Chen K, Reiman E, Brinton R. P1-135: Ovarian hormone loss induced decline in glucose availability and shift to alternative substrates in brain Alzheimer's & Dementia. 8: P153-P153. DOI: 10.1016/J.Jalz.2012.05.412 |
0.695 |
|
| 2012 |
Yao J, Ding F, Chen S, Mao Z, Cadenas E, Brinton R. P4-226: Shift in brain mitochondrial bioenergetics in aging and Alzheimer's: Implications for disease prevention and treatment Alzheimer's & Dementia. 8: P714-P714. DOI: 10.1016/J.Jalz.2012.05.1931 |
0.742 |
|
| 2011 |
Yao J, Rettberg JR, Klosinski LP, Cadenas E, Brinton RD. Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions. Molecular Aspects of Medicine. 32: 247-57. PMID 22024249 DOI: 10.1016/J.Mam.2011.10.005 |
0.822 |
|
| 2011 |
Chen S, Wang JM, Irwin RW, Yao J, Liu L, Brinton RD. Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease. Plos One. 6: e24293. PMID 21918687 DOI: 10.1371/Journal.Pone.0024293 |
0.774 |
|
| 2011 |
Yao J, Brinton RD. Targeting mitochondrial bioenergetics for Alzheimer's prevention and treatment. Current Pharmaceutical Design. 17: 3474-9. PMID 21902662 DOI: 10.2174/138161211798072517 |
0.706 |
|
| 2011 |
Yao J, Chen S, Mao Z, Cadenas E, Brinton RD. 2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease. Plos One. 6: e21788. PMID 21747957 DOI: 10.1371/Journal.Pone.0021788 |
0.677 |
|
| 2011 |
Irwin RW, Yao J, Ahmed SS, Hamilton RT, Cadenas E, Brinton RD. Medroxyprogesterone acetate antagonizes estrogen up-regulation of brain mitochondrial function. Endocrinology. 152: 556-67. PMID 21159850 DOI: 10.1210/En.2010-1061 |
0.759 |
|
| 2011 |
Yao J, Chen S, Cadenas E, Brinton RD. Estrogen protection against mitochondrial toxin-induced cell death in hippocampal neurons: antagonism by progesterone. Brain Research. 1379: 2-10. PMID 21134358 DOI: 10.1016/J.Brainres.2010.11.090 |
0.62 |
|
| 2011 |
Zhao L, Yao J, Mao Z, Chen S, Wang Y, Brinton RD. 17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention. Neurobiology of Aging. 32: 1949-63. PMID 20053478 DOI: 10.1016/J.Neurobiolaging.2009.12.010 |
0.615 |
|
| 2011 |
Diaz Brinton R, Yao J, Cadenas E. Estrogen, Mitochondrial Bioenergetics and Alzheimer's Disease. Biology of Reproduction. 85: 99-99. DOI: 10.1093/Biolreprod/85.S1.99 |
0.486 |
|
| 2011 |
Yao J, Chen S, Irwin R, Mao Z, Cadenas E, Brinton R. P3-476: Preclinical efficacy of 2-Deoxyglucose to sustain mitochondrial metabolic function and delay progression of Alzheimer's pathology Alzheimer's & Dementia. 7: S667-S668. DOI: 10.1016/J.Jalz.2011.05.1921 |
0.768 |
|
| 2010 |
Yao J, Hamilton RT, Cadenas E, Brinton RD. Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence. Biochimica Et Biophysica Acta. 1800: 1121-6. PMID 20538040 DOI: 10.1016/J.Bbagen.2010.06.002 |
0.687 |
|
| 2010 |
Irwin RW, Singh C, Liu L, Wang J, Yao J, Chen S, Henry S, Thompson RF, Brinton RD. P3-369: Allopregnanolone promotes neurogenesis, restores cognitive function and reduces Alzheimer's pathology in adult triple transgenic Alzheimer's mice: Preclinical development and formulation Alzheimer's & Dementia. 6: S560-S560. DOI: 10.1016/J.Jalz.2010.05.1911 |
0.772 |
|
| 2010 |
Yao J, Irwin R, Chen S, Brinton RD. P3-365: Deficits in mitochondrial bioenergetics and mitochondrial beta-amyloid deposition in brain are associated with reproductive senescence and loss of ovarian hormones: Prevention by estradiol Alzheimer's & Dementia. 6: S559-S559. DOI: 10.1016/J.Jalz.2010.05.1907 |
0.755 |
|
| 2009 |
Yao J, Irwin RW, Zhao L, Nilsen J, Hamilton RT, Brinton RD. Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 106: 14670-5. PMID 19667196 DOI: 10.1073/Pnas.0903563106 |
0.811 |
|
| 2008 |
Irwin RW, Yao J, Hamilton RT, Cadenas E, Brinton RD, Nilsen J. Progesterone and estrogen regulate oxidative metabolism in brain mitochondria. Endocrinology. 149: 3167-75. PMID 18292191 DOI: 10.1210/En.2007-1227 |
0.811 |
|
| 2007 |
Nilsen J, Irwin RW, Yao J, Brinton RD. P-073: Prevention of Alzheimer's pathology: Estrogen targeting of mitochondrial function Alzheimer's & Dementia. 3: S122-S122. DOI: 10.1016/J.Jalz.2007.04.326 |
0.799 |
|
| 2006 |
Mao Z, Yin F, Yao J, Brinton RD. P3-147: RESPONSE TO HORMONAL INTERVENTION IN AGING FEMALE BRAIN IS ENDOCRINE STATUS DEPENDENT: IMPLICATIONS FOR ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1124-P1124. DOI: 10.1016/J.Jalz.2018.06.1504 |
0.622 |
|
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