Zhihua Feng, Ph.D. - Publications

Affiliations: 
Biology: Doctor of Philosophy University of Southern California, Los Angeles, CA, United States 
Area:
Schwann cells, Neuromuscular junctions

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Miller N, Xu Z, Quinlan KA, Ji A, McGivern JV, Feng Z, Shi H, Ko CP, Tsai LH, Heckman CJ, Ebert AD, Ma YC. Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300308120. PMID 37976261 DOI: 10.1073/pnas.2300308120  0.682
2023 Kim JK, Jha NN, Awano T, Caine C, Gollapalli K, Welby E, Kim SS, Fuentes-Moliz A, Wang X, Feng Z, Sera F, Takeda T, Homma S, Ko CP, Tabares L, et al. A spinal muscular atrophy modifier implicates the SMN protein in SNARE complex assembly at neuromuscular synapses. Neuron. PMID 36863345 DOI: 10.1016/j.neuron.2023.02.004  0.7
2021 Zhao X, Feng Z, Risher N, Mollin A, Sheedy J, Ling KKY, Narasimhan J, Dakka A, Baird JD, Ratni H, Lutz C, Chen K, Naryshkin N, Ko CP, Welch E, et al. SMN protein is required throughout life to prevent spinal muscular atrophy disease progression. Human Molecular Genetics. PMID 34368854 DOI: 10.1093/hmg/ddab220  0.644
2021 Feng Z, Lam S, Tenn ES, Ghosh AS, Cantor S, Zhang W, Yen PF, Chen KS, Burden S, Paushkin S, Ayalon G, Ko CP. Activation of Muscle-Specific Kinase (MuSK) Reduces Neuromuscular Defects in the Delta7 Mouse Model of Spinal Muscular Atrophy (SMA). International Journal of Molecular Sciences. 22. PMID 34360794 DOI: 10.3390/ijms22158015  0.637
2020 Feng Z, Ling KKY, Zhao X, Zhou C, Karp G, Welch EM, Naryshkin N, Ratni H, Chen KS, Metzger F, Paushkin S, Weetall M, Ko CP. Corrigendum to: Pharmacologically-induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset. Human Molecular Genetics. PMID 33201218 DOI: 10.1093/hmg/ddaa247  0.589
2020 Osman EY, Van Alstyne M, Yen PF, Lotti F, Feng Z, Ling KK, Ko CP, Pellizzoni L, Lorson CL. Minor snRNA gene delivery improves the loss of proprioceptive synapses on SMA motor neurons. Jci Insight. PMID 32516136 DOI: 10.1172/Jci.Insight.130574  0.73
2020 Kim JK, Jha NN, Feng Z, Faleiro MR, Chiriboga CA, Wei-Lapierre L, Dirksen RT, Ko CP, Monani UR. Muscle-specific SMN reduction reveals motor neuron-independent disease in spinal muscular atrophy models. The Journal of Clinical Investigation. PMID 32039917 DOI: 10.1172/Jci131989  0.689
2019 Rimer M, Seaberg BL, Yen PF, Lam S, Hastings RL, Lee YI, Thompson WJ, Feng Z, Metzger F, Paushkin S, Ko CP. Nerve sprouting capacity in a pharmacologically induced mouse model of spinal muscular atrophy. Scientific Reports. 9: 7799. PMID 31127156 DOI: 10.1038/S41598-019-44222-2  0.687
2018 Ratni H, Ebeling M, Baird J, Bendels S, Bylund J, Chen KS, Denk N, Feng Z, Green L, Guerard M, Jablonski P, Jacobsen B, Khwaja O, Kletzl H, Ko CP, et al. Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA). Journal of Medicinal Chemistry. PMID 30044619 DOI: 10.1021/Acs.Jmedchem.8B00741  0.651
2016 Zhao X, Feng Z, Ling KK, Mollin A, Sheedy J, Yeh S, Petruska J, Narasimhan J, Dakka A, Welch E, Karp G, Chen KS, Metzger F, Ratni H, Lotti F, et al. Pharmacokinetics, Pharmacodynamics and Efficacy of a Small Molecule SMN2 Splicing Modifier in Mouse Models of Spinal Muscular Atrophy. Human Molecular Genetics. PMID 26931466 DOI: 10.1093/Hmg/Ddw062  0.696
2016 Zhou C, Feng Z, Ko CP. Defects in Motoneuron-Astrocyte Interactions in Spinal Muscular Atrophy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 2543-53. PMID 26911699 DOI: 10.1523/Jneurosci.3534-15.2016  0.671
2016 Shababi M, Feng Z, Villalon E, Sibigtroth CM, Osman EY, Miller MR, Williams-Simon PA, Lombardi A, Sass TH, Atkinson AK, Garcia ML, Ko CP, Lorson CL. Rescue of a Mouse Model of Spinal Muscular Atrophy with Respiratory Distress type 1 (SMARD1) by AAV9-IGHMBP2 is Dose Dependent. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26860981 DOI: 10.1038/Mt.2016.33  0.708
2016 Feng Z, Ling KK, Zhao X, Zhou C, Karp G, Welch EM, Naryshkin N, Ratni H, Chen KS, Metzger F, Paushkin S, Weetall M, Ko CP. Pharmacologically-induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset. Human Molecular Genetics. PMID 26758873 DOI: 10.1093/Hmg/Ddv629  0.713
2015 Feng ZQ, Franz EW, Leach MK, Winterroth F, White CM, Rastogi A, Gu ZZ, Corey JM. Mechanical tension applied to substrate films specifies location of neuritogenesis and promotes major neurite growth at the expense of minor neurite development. Journal of Biomedical Materials Research. Part A. PMID 26662937 DOI: 10.1002/Jbm.A.35627  0.324
2015 Rindt H, Feng Z, Mazzasette C, Glascock JJ, Valdivia D, Pyles N, Crawford TO, Swoboda KJ, Patitucci TN, Ebert AD, Sumner CJ, Ko CP, Lorson CL. Astrocytes influence the severity of spinal muscular atrophy. Human Molecular Genetics. 24: 4094-102. PMID 25911676 DOI: 10.1093/Hmg/Ddv148  0.76
2015 Miller N, Feng Z, Edens BM, Yang B, Shi H, Sze CC, Hong BT, Su SC, Cantu JA, Topczewski J, Crawford TO, Ko CP, Sumner CJ, Ma L, Ma YC. Non-aggregating tau phosphorylation by cyclin-dependent kinase 5 contributes to motor neuron degeneration in spinal muscular atrophy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6038-50. PMID 25878277 DOI: 10.1523/Jneurosci.3716-14.2015  0.688
2014 Naryshkin NA, Weetall M, Dakka A, Narasimhan J, Zhao X, Feng Z, Ling KK, Karp GM, Qi H, Woll MG, Chen G, Zhang N, Gabbeta V, Vazirani P, Bhattacharyya A, et al. Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy. Science (New York, N.Y.). 345: 688-93. PMID 25104390 DOI: 10.1126/Science.1250127  0.726
2013 Van Meerbeke JP, Gibbs RM, Plasterer HL, Miao W, Feng Z, Lin MY, Rucki AA, Wee CD, Xia B, Sharma S, Jacques V, Li DK, Pellizzoni L, Rusche JR, Ko CP, et al. The DcpS inhibitor RG3039 improves motor function in SMA mice. Human Molecular Genetics. 22: 4074-83. PMID 23727836 DOI: 10.1093/Hmg/Ddt257  0.78
2013 Cobb MS, Rose FF, Rindt H, Glascock JJ, Shababi M, Miller MR, Osman EY, Yen PF, Garcia ML, Martin BR, Wetz MJ, Mazzasette C, Feng Z, Ko CP, Lorson CL. Development and characterization of an SMN2-based intermediate mouse model of Spinal Muscular Atrophy. Human Molecular Genetics. 22: 1843-55. PMID 23390132 DOI: 10.1093/Hmg/Ddt037  0.753
2012 Osborne M, Gomez D, Feng Z, McEwen C, Beltran J, Cirillo K, El-Khodor B, Lin MY, Li Y, Knowlton WM, McKemy DD, Bogdanik L, Butts-Dehm K, Martens K, Davis C, et al. Characterization of behavioral and neuromuscular junction phenotypes in a novel allelic series of SMA mouse models. Human Molecular Genetics. 21: 4431-47. PMID 22802075 DOI: 10.1093/Hmg/Dds285  0.706
2012 Ling KK, Gibbs RM, Feng Z, Ko CP. Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy. Human Molecular Genetics. 21: 185-95. PMID 21968514 DOI: 10.1093/Hmg/Ddr453  0.641
2012 Van Meerbeke J, Gibbs R, Plasterer H, Feng Z, Lin M, Wee C, Xia B, Jacques V, Rusche J, Ko C, Sumner C. The Therapeutic Effects of RG3039 in Severe Spinal Muscular Atrophy Mice and Normal Human Volunteers (SC01.002) Neurology. 78: SC01.002-SC01.002. DOI: 10.1212/Wnl.78.1_Meetingabstracts.Sc01.002  0.768
2010 Ling KK, Lin MY, Zingg B, Feng Z, Ko CP. Synaptic defects in the spinal and neuromuscular circuitry in a mouse model of spinal muscular atrophy. Plos One. 5: e15457. PMID 21085654 DOI: 10.1371/Journal.Pone.0015457  0.765
2010 Feng Z, Ko CP. Schwann Cells and Plasticity of the Neuromuscular Junction Encyclopedia of Neuroscience. 491-496. DOI: 10.1016/B978-008045046-9.01269-9  0.51
2008 Feng Z, Ko CP. Schwann cells promote synaptogenesis at the neuromuscular junction via transforming growth factor-beta1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9599-609. PMID 18815246 DOI: 10.1523/Jneurosci.2589-08.2008  0.556
2008 Feng Z, Ko CP. The role of glial cells in the formation and maintenance of the neuromuscular junction. Annals of the New York Academy of Sciences. 1132: 19-28. PMID 18567850 DOI: 10.1196/Annals.1405.016  0.582
2007 Feng Z, Ko CP. Neuronal glia interactions at the vertebrate neuromuscular junction. Current Opinion in Pharmacology. 7: 316-24. PMID 17400025 DOI: 10.1016/J.Coph.2006.12.003  0.601
2007 Ko CP, Sugiura Y, Feng Z. The biology of perisynaptic (terminal) Schwann cells The Biology of Schwann Cells: Development, Differentiation and Immunomodulation. 72-99. DOI: 10.1017/CBO9780511541605.006  0.475
2005 Feng Z, Koirala S, Ko CP. Synapse-glia interactions at the vertebrate neuromuscular junction. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 11: 503-13. PMID 16151050 DOI: 10.1177/1073858405277409  0.684
2003 Peng HB, Yang JF, Dai Z, Lee CW, Hung HW, Feng ZH, Ko CP. Differential effects of neurotrophins and schwann cell-derived signals on neuronal survival/growth and synaptogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5050-60. PMID 12832528 DOI: 10.1523/Jneurosci.23-12-05050.2003  0.601
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