| Year |
Citation |
Score |
| 2023 |
Moshkov N, Becker T, Yang K, Horvath P, Dancik V, Wagner BK, Clemons PA, Singh S, Carpenter AE, Caicedo JC. Predicting compound activity from phenotypic profiles and chemical structures. Nature Communications. 14: 1967. PMID 37031208 DOI: 10.1038/s41467-023-37570-1 |
0.596 |
|
| 2023 |
Dahlin JL, Hua BK, Zucconi BE, Nelson SD, Singh S, Carpenter AE, Shrimp JH, Lima-Fernandes E, Wawer MJ, Chung LPW, Agrawal A, O'Reilly M, Barsyte-Lovejoy D, Szewczyk M, Li F, ... ... Wagner BK, et al. Reference compounds for characterizing cellular injury in high-content cellular morphology assays. Nature Communications. 14: 1364. PMID 36914634 DOI: 10.1038/s41467-023-36829-x |
0.691 |
|
| 2022 |
Lim D, Zhou Q, Cox KJ, Law BK, Lee M, Kokkonda P, Sreekanth V, Pergu R, Chaudhary SK, Gangopadhyay SA, Maji B, Lai S, Amako Y, Thompson DB, Subramanian HKK, ... ... Wagner BK, et al. A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules. Nature Cell Biology. PMID 36396978 DOI: 10.1038/s41556-022-01005-8 |
0.626 |
|
| 2022 |
Small JC, Joblin-Mills A, Carbone K, Kost-Alimova M, Ayukawa K, Khodier C, Dancik V, Clemons PA, Munkacsi AB, Wagner BK. Phenotypic Screening for Small Molecules that Protect β-Cells from Glucolipotoxicity. Acs Chemical Biology. PMID 35439415 DOI: 10.1021/acschembio.2c00052 |
0.607 |
|
| 2021 |
Negi V, Yang J, Speyer G, Pulgarin A, Handen A, Zhao J, Tai YY, Tang Y, Culley MK, Yu Q, Forsythe P, Gorelova A, Watson AM, Al Aaraj Y, Satoh T, ... ... Wagner BK, et al. Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension. Science Advances. 7: eabh3794. PMID 34669463 DOI: 10.1126/sciadv.abh3794 |
0.559 |
|
| 2021 |
Coussens NP, Auld DS, Thielman JR, Wagner BK, Dahlin JL. Addressing Compound Reactivity and Aggregation Assay Interferences: Case Studies of Biochemical High-Throughput Screening Campaigns Benefiting from the National Institutes of Health Guidelines. Slas Discovery : Advancing Life Sciences R & D. 24725552211026239. PMID 34218710 DOI: 10.1177/24725552211026239 |
0.77 |
|
| 2021 |
Clemons PA, Bittker JA, Wagner FF, Hands A, Dančík V, Schreiber SL, Choudhary A, Wagner BK. The Use of Informer Sets in Screening: Perspectives on an Efficient Strategy to Identify New Probes. Slas Discovery : Advancing Life Sciences R & D. 24725552211019410. PMID 34130532 DOI: 10.1177/24725552211019410 |
0.68 |
|
| 2021 |
Clemons PA, Bittker JA, Wagner FF, Hands A, Dančík V, Schreiber SL, Choudhary A, Wagner BK. The Use of Informer Sets in Screening: Perspectives on an Efficient Strategy to Identify New Probes. Slas Discovery : Advancing Life Sciences R & D. 24725552211019410. PMID 34130532 DOI: 10.1177/24725552211019410 |
0.68 |
|
| 2021 |
Hahn WC, Bader JS, Braun TP, Califano A, Clemons PA, Druker BJ, Ewald AJ, Fu H, Jagu S, Kemp CJ, Kim W, Kuo CJ, McManus M, B Mills G, Mo X, ... ... Wagner BK, et al. An expanded universe of cancer targets. Cell. 184: 1142-1155. PMID 33667368 DOI: 10.1016/j.cell.2021.02.020 |
0.632 |
|
| 2021 |
Dahlin JL, Auld DS, Rothenaigner I, Haney S, Sexton JZ, Nissink JWM, Walsh J, Lee JA, Strelow JM, Willard FS, Ferrins L, Baell JB, Walters MA, Hua BK, Hadian K, ... Wagner BK, et al. Nuisance compounds in cellular assays. Cell Chemical Biology. PMID 33592188 DOI: 10.1016/j.chembiol.2021.01.021 |
0.326 |
|
| 2020 |
Lim D, Sreekanth V, Cox KJ, Law BK, Wagner BK, Karp JM, Choudhary A. Engineering designer beta cells with a CRISPR-Cas9 conjugation platform. Nature Communications. 11: 4043. PMID 32792475 DOI: 10.1038/S41467-020-17725-0 |
0.351 |
|
| 2020 |
Dey M, Wagner B. The Role of Chemical Biology in the Discovery and Understanding of Ferroptosis. Cell Chemical Biology. 27: 363-364. PMID 32302581 DOI: 10.1016/J.Chembiol.2020.03.017 |
0.32 |
|
| 2020 |
Lee M, Maji B, Manna D, Kahraman S, Elgamal RM, Small J, Kokkonda P, Vetere A, Goldberg JM, Lippard SJ, Kulkarni RN, Wagner BK, Choudhary A. Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells. Journal of the American Chemical Society. PMID 32175731 DOI: 10.1021/Jacs.0C00099 |
0.369 |
|
| 2019 |
Li H, Ericsson M, Rabasha B, Budnik B, Chan SH, Freinkman E, Lewis CA, Doench JG, Wagner BK, Garraway LA, Schreiber SL. 6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels. Cell Chemical Biology. PMID 31204288 DOI: 10.1016/J.Chembiol.2019.05.006 |
0.48 |
|
| 2019 |
Maianti JP, Tan GA, Vetere A, Welsh AJ, Wagner BK, Seeliger MA, Liu DR. Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme. Nature Chemical Biology. PMID 31086331 DOI: 10.1038/S41589-019-0271-0 |
0.329 |
|
| 2019 |
Maji B, Gangopadhyay SA, Lee M, Shi M, Wu P, Heler R, Mok B, Lim D, Siriwardena SU, Paul B, Dančík V, Vetere A, Mesleh MF, Marraffini LA, Liu DR, ... ... Wagner BK, et al. A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9. Cell. 177: 1067-1079.e19. PMID 31051099 DOI: 10.1016/J.Cell.2019.04.009 |
0.682 |
|
| 2019 |
Zou Y, Palte MJ, Deik AA, Li H, Eaton JK, Wang W, Tseng YY, Deasy R, Kost-Alimova M, Dančík V, Leshchiner ES, Viswanathan VS, Signoretti S, Choueiri TK, Boehm JS, ... Wagner BK, et al. A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis. Nature Communications. 10: 1617. PMID 30962421 DOI: 10.1038/S41467-019-09277-9 |
0.746 |
|
| 2019 |
BASILE G, VETERE A, LIU K, HU J, ANDERSSON O, WAGNER B, KULKARNI R. 111-OR: Pancreatic Elastase Regulates Human Beta-Cell Proliferation via the Focal Adhesion and PAR2 Signaling Pathways Diabetes. 68: 111-OR. DOI: 10.2337/Db19-111-Or |
0.42 |
|
| 2018 |
DeRan M, Wagner BK. When Small Molecules Are Like Real Estate: It's All about Location, Location, Location. Cell Chemical Biology. 25: 1169-1170. PMID 30339956 DOI: 10.1016/J.Chembiol.2018.10.004 |
0.38 |
|
| 2018 |
Basile G, Vetere A, Hu J, Wagner B, Kulkarni R. Identification of Pancreatic Elastase Inhibitors That Can Stimulate Beta-Cell Proliferation Diabetes. 67. DOI: 10.2337/Db18-49-Or |
0.435 |
|
| 2017 |
Dirice E, Ng R, Martinez R, Hu J, Wagner FF, Holson EB, Wagner BK, Kulkarni RN. Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes. The Journal of Biological Chemistry. PMID 28860191 DOI: 10.1074/Jbc.M117.804328 |
0.328 |
|
| 2017 |
Rusu V, Hoch E, Mercader JM, Tenen DE, Gymrek M, Hartigan CR, DeRan M, von Grotthuss M, Fontanillas P, Spooner A, Guzman G, Deik AA, Pierce KA, Dennis C, Clish CB, ... ... Wagner BK, et al. Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms. Cell. 170: 199-212.e20. PMID 28666119 DOI: 10.1016/J.Cell.2017.06.011 |
0.436 |
|
| 2017 |
Lundh M, Bugliani M, Dahlby T, Hung-Chieh Chou D, Wagner B, Ghiasi SM, De Tata V, Chen Z, Nissen Lund M, Davies MJ, Marchetti P, Mandrup-Poulsen T. The immunoproteasome is induced by cytokines and regulates apoptosis in human islets. The Journal of Endocrinology. PMID 28438776 DOI: 10.1530/Joe-17-0110 |
0.369 |
|
| 2016 |
Baron M, Veres A, Wolock SL, Faust AL, Gaujoux R, Vetere A, Ryu JH, Wagner BK, Shen-Orr SS, Klein AM, Melton DA, Yanai I. A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure. Cell Systems. PMID 27667365 DOI: 10.1016/J.Cels.2016.08.011 |
0.382 |
|
| 2016 |
Gerhard DS, Clemons PA, Shamji AF, Hon C, Wagner BK, Schreiber SL, Krasnitz A, Sordella R, Sander C, Lowe SW, Powers S, Smith K, Aburi M, Iavarone A, Lasorella A, et al. Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance. Molecular Cancer Research : McR. PMID 27401613 DOI: 10.1158/1541-7786.Mcr-16-0090 |
0.783 |
|
| 2016 |
Gerry CJ, Hua BK, Wawer MJ, Knowles JP, Nelson SD, Verho O, Dandapani S, Wagner BK, Clemons PA, Booker-Milburn KI, Boskovic ZV, Schreiber SL. Real-Time Biological Annotation of Synthetic Compounds. Journal of the American Chemical Society. PMID 27398798 DOI: 10.1021/Jacs.6B04614 |
0.799 |
|
| 2016 |
Wagner BK. The Genetic Landscape of β-Cell Proliferation: Toward a Road Map. Diabetes. 65: 1789-90. PMID 27329954 DOI: 10.2337/Dbi16-0018 |
0.323 |
|
| 2016 |
Dirice E, Walpita D, Vetere A, Meier BC, Kahraman S, Hu J, Dančík V, Burns SM, Gilbert TJ, Olson DE, Clemons PA, Kulkarni RN, Wagner BK. Inhibition of DYRK1A stimulates human beta-cell proliferation. Diabetes. PMID 26953159 DOI: 10.2337/Db15-1127 |
0.612 |
|
| 2016 |
Wagner BK, Schreiber SL. The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods. Cell Chemical Biology. 23: 3-9. PMID 26933731 DOI: 10.1016/J.Chembiol.2015.11.008 |
0.558 |
|
| 2015 |
Rees MG, Seashore-Ludlow B, Cheah JH, Adams DJ, Price EV, Gill S, Javaid S, Coletti ME, Jones VL, Bodycombe NE, Soule CK, Alexander B, Li A, Montgomery P, Kotz JD, ... ... Wagner BK, et al. Correlating chemical sensitivity and basal gene expression reveals mechanism of action. Nature Chemical Biology. PMID 26656090 DOI: 10.1038/Nchembio.1986 |
0.821 |
|
| 2015 |
de Waal L, Lewis TA, Rees MG, Tsherniak A, Wu X, Choi PS, Gechijian L, Hartigan C, Faloon PW, Hickey MJ, Tolliday N, Carr SA, Clemons PA, Munoz B, Wagner BK, et al. Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics. Nature Chemical Biology. PMID 26656089 DOI: 10.1038/Nchembio.1984 |
0.813 |
|
| 2015 |
Wagner FF, Lundh M, Kaya T, McCarren P, Zhang YL, Chattopadhyay S, Gale JP, Galbo T, Fisher SL, Meier BC, Vetere A, Richardson S, Morgan NG, Christensen DP, Gilbert TJ, ... ... Wagner BK, et al. An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β-Cell Protection. Acs Chemical Biology. PMID 26640968 DOI: 10.1021/Acschembio.5B00640 |
0.406 |
|
| 2015 |
Wagner BK. The resurgence of phenotypic screening in drug discovery and development. Expert Opinion On Drug Discovery. PMID 26593688 DOI: 10.1517/17460441.2016.1122589 |
0.33 |
|
| 2015 |
Chou DH, Vetere A, Choudhary A, Scully SS, Schenone M, Tang A, Gomez R, Burns SM, Lundh M, Vital T, Comer E, Faloon PW, Dan?ík V, Ciarlo C, Paulk J, ... ... Wagner BK, et al. Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling. Journal of the American Chemical Society. 137: 7929-34. PMID 26042473 DOI: 10.1021/Jacs.5B04284 |
0.789 |
|
| 2015 |
Scully SS, Zheng SL, Wagner BK, Schreiber SL. Synthesis of oxazocenones via gold(I)-catalyzed 8-endo-dig hydroalkoxylation of alkynamides. Organic Letters. 17: 418-21. PMID 25569027 DOI: 10.1021/Ol503273V |
0.437 |
|
| 2015 |
Burns SM, Vetere A, Walpita D, Dan?ík V, Khodier C, Perez J, Clemons PA, Wagner BK, Altshuler D. High-throughput luminescent reporter of insulin secretion for discovering regulators of pancreatic Beta-cell function. Cell Metabolism. 21: 126-37. PMID 25565210 DOI: 10.1016/J.Cmet.2014.12.010 |
0.612 |
|
| 2015 |
Johannessen CM, Clemons PA, Wagner BK. Integrating phenotypic small-molecule profiling and human genetics: the next phase in drug discovery. Trends in Genetics : Tig. 31: 16-23. PMID 25498789 DOI: 10.1016/J.Tig.2014.11.002 |
0.656 |
|
| 2015 |
Waal Ld, Lewis TA, Rees MG, Tsherniak A, Wu X, Choi PS, Gechijian L, Hartigan C, Faloon PW, Hickey MJ, Tolliday N, Carr SA, Clemons PA, Munoz B, Wagner BK, et al. Abstract C136: Identification of selective cancer cytotoxic modulators of phosphodiesterase 3a by predictive chemogenomics Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-C136 |
0.802 |
|
| 2014 |
Walpita D, Wagner BK. Evaluation of compounds in primary human islet cell culture. Current Protocols in Chemical Biology. 6: 157-68. PMID 25205564 DOI: 10.1002/9780470559277.Ch140088 |
0.405 |
|
| 2014 |
Meier BC, Wagner BK. Inhibition of HDAC3 as a strategy for developing novel diabetes therapeutics. Epigenomics. 6: 209-14. PMID 24811789 DOI: 10.2217/Epi.14.11 |
0.335 |
|
| 2014 |
Choudhary A, Hu He K, Mertins P, Udeshi ND, Dan?ík V, Fomina-Yadlin D, Kubicek S, Clemons PA, Schreiber SL, Carr SA, Wagner BK. Quantitative-proteomic comparison of alpha and Beta cells to uncover novel targets for lineage reprogramming. Plos One. 9: e95194. PMID 24759943 DOI: 10.1371/Journal.Pone.0095194 |
0.662 |
|
| 2014 |
Wawer MJ, Jaramillo DE, Dan?ík V, Fass DM, Haggarty SJ, Shamji AF, Wagner BK, Schreiber SL, Clemons PA. Automated Structure-Activity Relationship Mining: Connecting Chemical Structure to Biological Profiles. Journal of Biomolecular Screening. 19: 738-748. PMID 24710340 DOI: 10.1177/1087057114530783 |
0.812 |
|
| 2014 |
Vetere A, Choudhary A, Burns SM, Wagner BK. Targeting the pancreatic β-cell to treat diabetes. Nature Reviews. Drug Discovery. 13: 278-89. PMID 24525781 DOI: 10.1038/Nrd4231 |
0.311 |
|
| 2014 |
Dan?ík V, Carrel H, Bodycombe NE, Seiler KP, Fomina-Yadlin D, Kubicek ST, Hartwell K, Shamji AF, Wagner BK, Clemons PA. Connecting Small Molecules with Similar Assay Performance Profiles Leads to New Biological Hypotheses. Journal of Biomolecular Screening. 19: 771-781. PMID 24464433 DOI: 10.1177/1087057113520226 |
0.776 |
|
| 2013 |
Yuan Y, Hartland K, Boskovic Z, Wang Y, Walpita D, Lysy PA, Zhong C, Young DW, Kim YK, Tolliday NJ, Sokal EM, Schreiber SL, Wagner BK. A small-molecule inducer of PDX1 expression identified by high-throughput screening. Chemistry & Biology. 20: 1513-22. PMID 24290880 DOI: 10.1016/J.Chembiol.2013.10.013 |
0.796 |
|
| 2013 |
Lundh M, Scully SS, Mandrup-Poulsen T, Wagner BK. Small-molecule inhibition of inflammatory β-cell death. Diabetes, Obesity & Metabolism. 15: 176-84. PMID 24003935 DOI: 10.1111/Dom.12158 |
0.393 |
|
| 2013 |
Yuan Y, Tang AJ, Castoreno AB, Kuo SY, Wang Q, Kuballa P, Xavier R, Shamji AF, Schreiber SL, Wagner BK. Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells. Cell Death & Disease. 4: e690. PMID 23807219 DOI: 10.1038/cddis.2013.191 |
0.753 |
|
| 2013 |
Scully SS, Tang AJ, Lundh M, Mosher CM, Perkins KM, Wagner BK. Small-molecule inhibitors of cytokine-mediated STAT1 signal transduction in β-cells with improved aqueous solubility. Journal of Medicinal Chemistry. 56: 4125-9. PMID 23617753 DOI: 10.1021/Jm400397X |
0.406 |
|
| 2013 |
Schenone M, Dan?ík V, Wagner BK, Clemons PA. Target identification and mechanism of action in chemical biology and drug discovery. Nature Chemical Biology. 9: 232-40. PMID 23508189 DOI: 10.1038/Nchembio.1199 |
0.644 |
|
| 2013 |
Adams DJ, Boskovic ZV, Theriault JR, Wang AJ, Stern AM, Wagner BK, Shamji AF, Schreiber SL. Discovery of small-molecule enhancers of reactive oxygen species that are nontoxic or cause genotype-selective cell death. Acs Chemical Biology. 8: 923-9. PMID 23477340 DOI: 10.1021/Cb300653V |
0.813 |
|
| 2012 |
Adams DJ, Dai M, Pellegrino G, Wagner BK, Stern AM, Shamji AF, Schreiber SL. Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs. Proceedings of the National Academy of Sciences of the United States of America. 109: 15115-20. PMID 22949699 DOI: 10.1073/Pnas.1212802109 |
0.775 |
|
| 2012 |
Vetere A, Wagner BK. Chemical methods to induce Beta-cell proliferation. International Journal of Endocrinology. 2012: 925143. PMID 22811709 DOI: 10.1155/2012/925143 |
0.408 |
|
| 2012 |
Chou DH, Holson EB, Wagner FF, Tang AJ, Maglathlin RL, Lewis TA, Schreiber SL, Wagner BK. Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis. Chemistry & Biology. 19: 669-73. PMID 22726680 DOI: 10.1016/J.Chembiol.2012.05.010 |
0.72 |
|
| 2012 |
Yuan Y, Wang Q, Paulk J, Kubicek S, Kemp MM, Adams DJ, Shamji AF, Wagner BK, Schreiber SL. A small-molecule probe of the histone methyltransferase G9a induces cellular senescence in pancreatic adenocarcinoma. Acs Chemical Biology. 7: 1152-7. PMID 22536950 DOI: 10.1021/Cb300139Y |
0.792 |
|
| 2012 |
Kubicek S, Gilbert JC, Fomina-Yadlin D, Gitlin AD, Yuan Y, Wagner FF, Holson EB, Luo T, Lewis TA, Taylor B, Gupta S, Shamji AF, Wagner BK, Clemons PA, Schreiber SL. Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 5364-9. PMID 22434908 DOI: 10.1073/Pnas.1201079109 |
0.804 |
|
| 2012 |
Fomina-Yadlin D, Kubicek S, Vetere A, He KH, He KH, Schreiber SL, Wagner BK. GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity. Plos One. 7: e28808. PMID 22242153 DOI: 10.1371/Journal.Pone.0028808 |
0.511 |
|
| 2012 |
Walpita D, Hasaka T, Spoonamore J, Vetere A, Takane KK, Fomina-Yadlin D, Fiaschi-Taesch N, Shamji A, Clemons PA, Stewart AF, Schreiber SL, Wagner BK. A human islet cell culture system for high-throughput screening. Journal of Biomolecular Screening. 17: 509-18. PMID 22156222 DOI: 10.1177/1087057111430253 |
0.783 |
|
| 2011 |
Chou DH, Duvall JR, Gerard B, Liu H, Pandya BA, Suh BC, Forbeck EM, Faloon P, Wagner BK, Marcaurelle LA. Synthesis of a novel suppressor of beta-cell apoptosis via diversity-oriented synthesis. Acs Medicinal Chemistry Letters. 2: 698-702. PMID 21927648 DOI: 10.1021/Ml200120M |
0.718 |
|
| 2011 |
Wagner BK, Gilbert TJ, Hanai J, Imamura S, Bodycombe NE, Bon RS, Waldmann H, Clemons PA, Sukhatme VP, Mootha VK. A small-molecule screening strategy to identify suppressors of statin myopathy. Acs Chemical Biology. 6: 900-4. PMID 21732624 DOI: 10.1021/Cb200206W |
0.614 |
|
| 2011 |
Clemons PA, Wilson JA, Dan?ík V, Muller S, Carrinski HA, Wagner BK, Koehler AN, Schreiber SL. Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections. Proceedings of the National Academy of Sciences of the United States of America. 108: 6817-22. PMID 21482810 DOI: 10.1073/Pnas.1015024108 |
0.795 |
|
| 2011 |
Bochner BR, Siri M, Huang RH, Noble S, Lei XH, Clemons PA, Wagner BK. Assay of the multiple energy-producing pathways of mammalian cells. Plos One. 6: e18147. PMID 21455318 DOI: 10.1371/Journal.Pone.0018147 |
0.599 |
|
| 2011 |
Wagner BK. Screening: Low-fat worms on drugs. Nature Chemical Biology. 7: 194-5. PMID 21423161 DOI: 10.1038/Nchembio.540 |
0.369 |
|
| 2011 |
Kim YK, Lee JS, Bi X, Ha HH, Ng SH, Ahn YH, Lee JJ, Wagner BK, Clemons PA, Chang YT. The binding of fluorophores to proteins depends on the cellular environment. Angewandte Chemie (International Ed. in English). 50: 2761-3. PMID 21370369 DOI: 10.1002/Anie.201007626 |
0.622 |
|
| 2011 |
Kim YK, Lee J, Bi X, Ha H, Ng SH, Ahn Y, Lee J, Wagner BK, Clemons PA, Chang Y. Cover Picture: The Binding of Fluorophores to Proteins Depends on the Cellular Environment (Angew. Chem. Int. Ed. 12/2011) Angewandte Chemie International Edition. 50: 2649-2649. DOI: 10.1002/Anie.201101113 |
0.557 |
|
| 2011 |
Kim YK, Lee J, Bi X, Ha H, Ng SH, Ahn Y, Lee J, Wagner BK, Clemons PA, Chang Y. Titelbild: The Binding of Fluorophores to Proteins Depends on the Cellular Environment (Angew. Chem. 12/2011) Angewandte Chemie. 123: 2699-2699. DOI: 10.1002/Ange.201101113 |
0.555 |
|
| 2010 |
Wagner BK. Grand challenge commentary: Chemical transdifferentiation and regenerative medicine. Nature Chemical Biology. 6: 877-9. PMID 21079596 DOI: 10.1038/Nchembio.472 |
0.382 |
|
| 2010 |
Clemons PA, Bodycombe NE, Carrinski HA, Wilson JA, Shamji AF, Wagner BK, Koehler AN, Schreiber SL. Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles. Proceedings of the National Academy of Sciences of the United States of America. 107: 18787-92. PMID 20956335 DOI: 10.1073/Pnas.1012741107 |
0.804 |
|
| 2010 |
Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, et al. Towards patient-based cancer therapeutics. Nature Biotechnology. 28: 904-6. PMID 20829823 DOI: 10.1038/Nbt0910-904 |
0.781 |
|
| 2010 |
Fomina-Yadlin D, Kubicek S, Walpita D, Dancik V, Hecksher-Sørensen J, Bittker JA, Sharifnia T, Shamji A, Clemons PA, Wagner BK, Schreiber SL. Small-molecule inducers of insulin expression in pancreatic alpha-cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 15099-104. PMID 20696901 DOI: 10.1073/Pnas.1010018107 |
0.789 |
|
| 2010 |
Chou DH, Bodycombe NE, Carrinski HA, Lewis TA, Clemons PA, Schreiber SL, Wagner BK. Small-Molecule Suppressors of Cytokine-Induced beta-Cell Apoptosis. Acs Chemical Biology. 5: 729-34. PMID 20550176 DOI: 10.1021/Cb100129D |
0.8 |
|
| 2009 |
Wagner BK, Clemons PA. Connecting synthetic chemistry decisions to cell and genome biology using small-molecule phenotypic profiling. Current Opinion in Chemical Biology. 13: 539-48. PMID 19825513 DOI: 10.1016/J.Cbpa.2009.09.018 |
0.657 |
|
| 2009 |
Wagner BK, Arany Z. High-throughput real-time PCR for detection of gene-expression levels. Methods in Molecular Biology (Clifton, N.J.). 486: 167-75. PMID 19347623 DOI: 10.1007/978-1-60327-545-3_12 |
0.369 |
|
| 2009 |
Tanikawa T, Fridman M, Zhu W, Faulk B, Joseph IC, Kahne D, Wagner BK, Clemons PA. Using biological performance similarity to inform disaccharide library design. Journal of the American Chemical Society. 131: 5075-83. PMID 19298063 DOI: 10.1021/Ja806583Y |
0.628 |
|
| 2008 |
Arany Z, Wagner BK, Ma Y, Chinsomboon J, Laznik D, Spiegelman BM. Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1alpha and oxidative phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 105: 4721-6. PMID 18347329 DOI: 10.1073/Pnas.0800979105 |
0.337 |
|
| 2008 |
Wagner BK, Carrinski HA, Ahn YH, Kim YK, Gilbert TJ, Fomina DA, Schreiber SL, Chang YT, Clemons PA. Small-molecule fluorophores to detect cell-state switching in the context of high-throughput screening. Journal of the American Chemical Society. 130: 4208-9. PMID 18327938 DOI: 10.1021/Ja077656D |
0.748 |
|
| 2008 |
Wagner BK, Kitami T, Gilbert TJ, Peck D, Ramanathan A, Schreiber SL, Golub TR, Mootha VK. Large-scale chemical dissection of mitochondrial function. Nature Biotechnology. 26: 343-51. PMID 18297058 DOI: 10.1038/Nbt1387 |
0.495 |
|
| 2008 |
Wagner BK, Kitami T, Gilbert TJ, Peck D, Ramanathan A, Schreiber SL, Golub TR, Mootha VK. Large-scale chemical dissection of mitochondrial function (Nature Biotechnology (2008) 26 (343-351)) Nature Biotechnology. 26: 831. DOI: 10.1038/Nbt0708-831A |
0.413 |
|
| 2004 |
Wagner BK, Haggarty SJ, Clemons PA. Chemical genomics: probing protein function using small molecules. American Journal of Pharmacogenomics : Genomics-Related Research in Drug Development and Clinical Practice. 4: 313-20. PMID 15462609 DOI: 10.2165/00129785-200404050-00004 |
0.713 |
|
| 2002 |
Wagner BK, Clemons PA. Dual-purpose drug discovery Trends in Biotechnology. 20: 492-493. DOI: 10.1016/S0167-7799(02)02097-8 |
0.577 |
|
| 2002 |
Wagner BK, Clemons PA. An even-handed approach Trends in Biotechnology. 20: 53. DOI: 10.1016/S0167-7799(01)01927-8 |
0.585 |
|
| 2001 |
Clemons PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, Foley MA. A one-bead, one-stock solution approach to chemical genetics: part 2. Chemistry & Biology. 8: 1183-95. PMID 11755397 DOI: 10.1016/S1074-5521(01)00086-2 |
0.801 |
|
| 2001 |
Clemons PA, Wagner BK. Hay in a needlestack? Trends in Biotechnology. 19: 435-436. DOI: 10.1016/S0167-7799(01)01848-0 |
0.496 |
|
| 2001 |
Wagner BK, Clemons PA. Better signaling through chemistry Trends in Biotechnology. 19: 127. DOI: 10.1016/S0167-7799(01)01611-0 |
0.578 |
|
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