| Year |
Citation |
Score |
| 2020 |
Viereck J, Bührke A, Foinquinos A, Chatterjee S, Kleeberger JA, Xiao K, Janssen-Peters H, Batkai S, Ramanujam D, Kraft T, Cebotari S, Gueler F, Beyer AM, Schmitz J, Bräsen JH, ... ... Engelhardt S, et al. Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy. European Heart Journal. PMID 32657324 DOI: 10.1093/Eurheartj/Ehaa519 |
0.327 |
|
| 2020 |
Trembinski DJ, Bink DI, Theodorou K, Sommer J, Fischer A, van Bergen A, Kuo CC, Costa IG, Schürmann C, Leisegang MS, Brandes RP, Alekseeva T, Brill B, Wietelmann A, Johnson CN, ... ... Engelhardt S, et al. Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction. Nature Communications. 11: 2039. PMID 32341350 DOI: 10.1038/S41467-020-15995-2 |
0.326 |
|
| 2020 |
Hinkel R, Ramanujam D, Kaczmarek V, Howe A, Klett K, Beck C, Dueck A, Thum T, Laugwitz KL, Maegdefessel L, Weber C, Kupatt C, Engelhardt S. AntimiR-21 Prevents Myocardial Dysfunction in a Pig Model of Ischemia/Reperfusion Injury. Journal of the American College of Cardiology. 75: 1788-1800. PMID 32299591 DOI: 10.1016/J.Jacc.2020.02.041 |
0.338 |
|
| 2018 |
Rasanen MOH, Amudhala Hemanthakumar K, Paech JB, Robciuc MR, Ramanujam D, Lahteenvuo JB, Engelhardt S, Kivela R, Alitalo K. 234Models for VEGF-B induced physiological and pathological cardiac hypertrophy Cardiovascular Research. 114: S60-S60. DOI: 10.1093/Cvr/Cvy060.165 |
0.303 |
|
| 2017 |
Ziegler KA, Ahles A, Wille T, Kerler J, Ramanujam D, Engelhardt S. Local sympathetic denervation attenuates myocardial inflammation and improves cardiac function after myocardial infarction in mice. Cardiovascular Research. PMID 29186414 DOI: 10.1093/Cvr/Cvx227 |
0.368 |
|
| 2017 |
Wang J, Hanada K, Staus DP, Makara MA, Dahal GR, Chen Q, Ahles A, Engelhardt S, Rockman HA. Gαi is required for carvedilol-induced β1 adrenergic receptor β-arrestin biased signaling. Nature Communications. 8: 1706. PMID 29167435 DOI: 10.1038/S41467-017-01855-Z |
0.362 |
|
| 2017 |
Sassi Y, Avramopoulos P, Ramanujam D, Grüter L, Werfel S, Giosele S, Brunner AD, Esfandyari D, Papadopoulou AS, De Strooper B, Hübner N, Kumarswamy R, Thum T, Yin X, Mayr M, ... ... Engelhardt S, et al. Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling. Nature Communications. 8: 1614. PMID 29158499 DOI: 10.1038/S41467-017-01737-4 |
0.351 |
|
| 2017 |
Toischer K, Zhu W, Hünlich M, Mohamed BA, Khadjeh S, Reuter SP, Schäfer K, Ramanujam D, Engelhardt S, Field LJ, Hasenfuss G. Cardiomyocyte proliferation prevents failure in pressure overload but not volume overload. The Journal of Clinical Investigation. PMID 29083322 DOI: 10.1172/Jci81870 |
0.334 |
|
| 2017 |
Hinz L, Ahles A, Ruprecht B, Küster B, Engelhardt S. Two serines in the distal C-terminus of the human ß1-adrenoceptor determine ß-arrestin2 recruitment. Plos One. 12: e0176450. PMID 28472170 DOI: 10.1371/Journal.Pone.0176450 |
0.364 |
|
| 2017 |
Poller W, Dimmeler S, Heymans S, Zeller T, Haas J, Karakas M, Leistner DM, Jakob P, Nakagawa S, Blankenberg S, Engelhardt S, Thum T, Weber C, Meder B, Hajjar R, et al. Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives. European Heart Journal. PMID 28430919 DOI: 10.1093/Eurheartj/Ehx165 |
0.302 |
|
| 2016 |
Ramanujam D, Sassi Y, Laggerbauer B, Engelhardt S. Viral vector-based targeting of miR-21 in cardiac non-myocyte cells reduces pathologic remodeling of the heart. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27545313 DOI: 10.1038/Mt.2016.166 |
0.35 |
|
| 2016 |
Regn M, Laggerbauer B, Jentzsch C, Ramanujam D, Ahles A, Sichler S, Calzada-Wack J, Koenen R, Braun A, Nieswandt B, Engelhardt S. Peptidase inhibitor 16 is a membrane-tethered regulator of chemerin processing in the myocardium. Journal of Molecular and Cellular Cardiology. PMID 27539859 DOI: 10.1016/J.Yjmcc.2016.08.010 |
0.361 |
|
| 2016 |
Werfel S, Nothjunge S, Schwarzmayr T, Strom TM, Meitinger T, Engelhardt S. Characterization of circular RNAs in human, mouse and rat hearts. Journal of Molecular and Cellular Cardiology. PMID 27476877 DOI: 10.1016/J.Yjmcc.2016.07.007 |
0.32 |
|
| 2016 |
Meyer K, Hodwin B, Ramanujam D, Engelhardt S, Sarikas A. Essential Role for Premature Senescence of Myofibroblasts in Myocardial Fibrosis. Journal of the American College of Cardiology. 67: 2018-28. PMID 27126529 DOI: 10.1016/J.Jacc.2016.02.047 |
0.324 |
|
| 2016 |
Viereck J, Kumarswamy R, Foinquinos A, Xiao K, Avramopoulos P, Kunz M, Dittrich M, Maetzig T, Zimmer K, Remke J, Just A, Fendrich J, Scherf K, Bolesani E, Schambach A, ... ... Engelhardt S, et al. Long noncoding RNA Chast promotes cardiac remodeling. Science Translational Medicine. 8: 326ra22. PMID 26888430 DOI: 10.1126/Scitranslmed.Aaf1475 |
0.387 |
|
| 2015 |
Keller K, Maaß M, Dizayee S, Leiss V, Annala S, Köth J, Seemann W, Müller-Ehmsen J, Mohr K, Nürnberg B, Engelhardt S, Herzig S, Birnbaumer L, Matthes J. Lack of Gαi2 leads to dilative cardiomyopathy and increased mortality in β1-adrenoceptor overexpressing mice. Cardiovascular Research. PMID 26464333 DOI: 10.1093/Cvr/Cvv235 |
0.387 |
|
| 2015 |
Truong DJ, Kühner K, Kühn R, Werfel S, Engelhardt S, Wurst W, Ortiz O. Development of an intein-mediated split-Cas9 system for gene therapy. Nucleic Acids Research. PMID 26082496 DOI: 10.1093/Nar/Gkv601 |
0.732 |
|
| 2015 |
Ahles A, Rodewald F, Rochais F, Bünemann M, Engelhardt S. Interhelical interaction and receptor phosphorylation regulate the activation kinetics of different human β1-adrenoceptor variants. The Journal of Biological Chemistry. 290: 1760-9. PMID 25451930 DOI: 10.1074/Jbc.M114.607333 |
0.648 |
|
| 2014 |
Sassi Y, Ahles A, Truong DJ, Baqi Y, Lee SY, Husse B, Hulot JS, Foinquinos A, Thum T, Müller CE, Dendorfer A, Laggerbauer B, Engelhardt S. Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation. The Journal of Clinical Investigation. 124: 5385-97. PMID 25401477 DOI: 10.1172/Jci74349 |
0.782 |
|
| 2014 |
Friedrich FW, Reischmann S, Schwalm A, Unger A, Ramanujam D, Münch J, Müller OJ, Hengstenberg C, Galve E, Charron P, Linke WA, Engelhardt S, Patten M, Richard P, van der Velden J, et al. FHL2 expression and variants in hypertrophic cardiomyopathy. Basic Research in Cardiology. 109: 451. PMID 25358972 DOI: 10.1007/S00395-014-0451-8 |
0.39 |
|
| 2014 |
Werfel S, Jungmann A, Lehmann L, Ksienzyk J, Bekeredjian R, Kaya Z, Leuchs B, Nordheim A, Backs J, Engelhardt S, Katus HA, Müller OJ. Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase. Cardiovascular Research. 104: 15-23. PMID 25082846 DOI: 10.1093/Cvr/Cvu174 |
0.356 |
|
| 2014 |
Ahles A, Engelhardt S. Polymorphic variants of adrenoceptors: pharmacology, physiology, and role in disease. Pharmacological Reviews. 66: 598-637. PMID 24928328 DOI: 10.1124/Pr.113.008219 |
0.335 |
|
| 2014 |
Bang C, Batkai S, Dangwal S, Gupta SK, Foinquinos A, Holzmann A, Just A, Remke J, Zimmer K, Zeug A, Ponimaskin E, Schmiedl A, Yin X, Mayr M, Halder R, ... ... Engelhardt S, et al. Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy. The Journal of Clinical Investigation. 124: 2136-46. PMID 24743145 DOI: 10.1172/Jci70577 |
0.329 |
|
| 2014 |
Hartmann T, Xu X, Kronast M, Muehlich S, Meyer K, Zimmermann W, Hurwitz J, Pan ZQ, Engelhardt S, Sarikas A. Inhibition of Cullin-RING E3 ubiquitin ligase 7 by simian virus 40 large T antigen. Proceedings of the National Academy of Sciences of the United States of America. 111: 3371-6. PMID 24550499 DOI: 10.1073/Pnas.1401556111 |
0.325 |
|
| 2013 |
Gurha P, Wang T, Larimore AH, Sassi Y, Abreu-Goodger C, Ramirez MO, Reddy AK, Engelhardt S, Taffet GE, Wehrens XH, Entman ML, Rodriguez A. microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription. Plos One. 8: e75882. PMID 24086656 DOI: 10.1371/Journal.Pone.0075882 |
0.34 |
|
| 2013 |
Milde M, Rinne A, Wunder F, Engelhardt S, Bünemann M. Dynamics of Gαi1 interaction with type 5 adenylate cyclase reveal the molecular basis for high sensitivity of Gi-mediated inhibition of cAMP production. The Biochemical Journal. 454: 515-23. PMID 23841650 DOI: 10.1042/Bj20130554 |
0.636 |
|
| 2013 |
Ganesan J, Ramanujam D, Sassi Y, Ahles A, Jentzsch C, Werfel S, Leierseder S, Loyer X, Giacca M, Zentilin L, Thum T, Laggerbauer B, Engelhardt S. MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors. Circulation. 127: 2097-106. PMID 23625957 DOI: 10.1161/Circulationaha.112.000882 |
0.314 |
|
| 2012 |
Ucar A, Gupta SK, Fiedler J, Erikci E, Kardasinski M, Batkai S, Dangwal S, Kumarswamy R, Bang C, Holzmann A, Remke J, Caprio M, Jentzsch C, Engelhardt S, Geisendorf S, et al. The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy. Nature Communications. 3: 1078. PMID 23011132 DOI: 10.1038/Ncomms2090 |
0.337 |
|
| 2012 |
Ziegler M, Elvers M, Baumer Y, Leder C, Ochmann C, Schönberger T, Jürgens T, Geisler T, Schlosshauer B, Lunov O, Engelhardt S, Simmet T, Gawaz M. The bispecific SDF1-GPVI fusion protein preserves myocardial function after transient ischemia in mice. Circulation. 125: 685-96. PMID 22223428 DOI: 10.1161/Circulationaha.111.070508 |
0.342 |
|
| 2012 |
Sassi Y, Abi-Gerges A, Fauconnier J, Mougenot N, Reiken S, Haghighi K, Kranias EG, Marks AR, Lacampagne A, Engelhardt S, Hatem SN, Lompre AM, Hulot JS. Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1009-17. PMID 22090316 DOI: 10.1096/Fj.11-194027 |
0.393 |
|
| 2011 |
Ahles A, Rochais F, Frambach T, Bünemann M, Engelhardt S. A polymorphism-specific "memory" mechanism in the β(2)-adrenergic receptor. Science Signaling. 4: ra53. PMID 21868359 DOI: 10.1126/Scisignal.2001681 |
0.661 |
|
| 2011 |
Fiedler J, Jazbutyte V, Kirchmaier BC, Gupta SK, Lorenzen J, Hartmann D, Galuppo P, Kneitz S, Pena JT, Sohn-Lee C, Loyer X, Soutschek J, Brand T, Tuschl T, Heineke J, ... ... Engelhardt S, et al. MicroRNA-24 regulates vascularity after myocardial infarction. Circulation. 124: 720-30. PMID 21788589 DOI: 10.1161/Circulationaha.111.039008 |
0.344 |
|
| 2009 |
Ahles A, Engelhardt S. Polymorphisms determine beta-adrenoceptor conformation: implications for cardiovascular disease and therapy. Trends in Pharmacological Sciences. 30: 188-93. PMID 19272658 DOI: 10.1016/J.Tips.2009.02.001 |
0.434 |
|
| 2009 |
Dorsch S, Klotz KN, Engelhardt S, Lohse MJ, Bünemann M. Analysis of receptor oligomerization by FRAP microscopy. Nature Methods. 6: 225-30. PMID 19234451 DOI: 10.1038/Nmeth.1304 |
0.721 |
|
| 2009 |
Vilardaga JP, Bünemann M, Feinstein TN, Lambert N, Nikolaev VO, Engelhardt S, Lohse MJ, Hoffmann C. GPCR and G proteins: drug efficacy and activation in live cells. Molecular Endocrinology (Baltimore, Md.). 23: 590-9. PMID 19196832 DOI: 10.1210/Me.2008-0204 |
0.746 |
|
| 2009 |
Lewin G, Matus M, Basu A, Frebel K, Rohsbach SP, Safronenko A, Seidl MD, Stümpel F, Buchwalow I, König S, Engelhardt S, Lohse MJ, Schmitz W, Müller FU. Critical role of transcription factor cyclic AMP response element modulator in beta1-adrenoceptor-mediated cardiac dysfunction. Circulation. 119: 79-88. PMID 19103994 DOI: 10.1161/Circulationaha.108.786533 |
0.632 |
|
| 2009 |
Cook AR, Bardswell SC, Pretheshan S, Dighe K, Kanaganayagam GS, Jabr RI, Merkle S, Marber MS, Engelhardt S, Avkiran M. Paradoxical resistance to myocardial ischemia and age-related cardiomyopathy in NHE1 transgenic mice: a role for ER stress? Journal of Molecular and Cellular Cardiology. 46: 225-33. PMID 19027022 DOI: 10.1016/J.Yjmcc.2008.10.013 |
0.371 |
|
| 2008 |
Thum T, Gross C, Fiedler J, Fischer T, Kissler S, Bussen M, Galuppo P, Just S, Rottbauer W, Frantz S, Castoldi M, Soutschek J, Koteliansky V, Rosenwald A, Basson MA, ... ... Engelhardt S, et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature. 456: 980-4. PMID 19043405 DOI: 10.1038/Nature07511 |
0.37 |
|
| 2008 |
Thum T, Gross C, Fiedler J, Galuppo P, Frantz S, Hu K, Ertl G, Engelhardt S, Bauersachs J. 584 Prevention of cardiac hypertrophy and failure in vivo by a novel microRNA antagonist European Journal of Heart Failure Supplements. 7: 146-146. DOI: 10.1016/S1567-4215(08)60418-X |
0.389 |
|
| 2007 |
Rohrbach S, Engelhardt S, Lohse MJ, Werdan K, Holtz J, Muller-Werdan U. Activation of AP-1 contributes to the beta-adrenoceptor-mediated myocardial induction of interleukin-6. Molecular Medicine (Cambridge, Mass.). 13: 605-14. PMID 17948064 DOI: 10.2119/2007-00071.Rohrbach |
0.514 |
|
| 2007 |
Frost RJ, Engelhardt S. A secretion trap screen in yeast identifies protease inhibitor 16 as a novel antihypertrophic protein secreted from the heart. Circulation. 116: 1768-75. PMID 17909105 DOI: 10.1161/Circulationaha.107.696468 |
0.359 |
|
| 2007 |
Engelhardt S. Alternative signaling: cardiomyocyte beta1-adrenergic receptors signal through EGFRs. The Journal of Clinical Investigation. 117: 2396-8. PMID 17786237 DOI: 10.1172/Jci33135 |
0.464 |
|
| 2007 |
Thum T, Galuppo P, Wolf C, Fiedler J, Kneitz S, van Laake LW, Doevendans PA, Mummery CL, Borlak J, Haverich A, Gross C, Engelhardt S, Ertl G, Bauersachs J. MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation. 116: 258-67. PMID 17606841 DOI: 10.1161/CIRCULATIONAHA.107.687947 |
0.349 |
|
| 2007 |
Engelhardt S, Rochais F. G proteins: more than transducers of receptor-generated signals? Circulation Research. 100: 1109-11. PMID 17463326 DOI: 10.1161/01.Res.0000266971.15127.E8 |
0.374 |
|
| 2007 |
Peter PS, Brady JE, Yan L, Chen W, Engelhardt S, Wang Y, Sadoshima J, Vatner SF, Vatner DE. Inhibition of p38 alpha MAPK rescues cardiomyopathy induced by overexpressed beta 2-adrenergic receptor, but not beta 1-adrenergic receptor. The Journal of Clinical Investigation. 117: 1335-43. PMID 17446930 DOI: 10.1172/Jci29576 |
0.429 |
|
| 2007 |
Merkle S, Frantz S, Schön MP, Bauersachs J, Buitrago M, Frost RJ, Schmitteckert EM, Lohse MJ, Engelhardt S. A role for caspase-1 in heart failure. Circulation Research. 100: 645-53. PMID 17303764 DOI: 10.1161/01.Res.0000260203.55077.61 |
0.521 |
|
| 2007 |
Rochais F, Vilardaga JP, Nikolaev VO, Bünemann M, Lohse MJ, Engelhardt S. Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol. The Journal of Clinical Investigation. 117: 229-35. PMID 17200720 DOI: 10.1172/Jci30012 |
0.786 |
|
| 2007 |
Seeland U, Selejan S, Engelhardt S, Müller P, Lohse MJ, Böhm M. Interstitial remodeling in beta1-adrenergic receptor transgenic mice. Basic Research in Cardiology. 102: 183-93. PMID 17122889 DOI: 10.1007/S00395-006-0635-Y |
0.525 |
|
| 2007 |
Cook A, Engelhardt S, Avkiran M. Paradoxical resistance to ischaemic injury in hearts of NHE1-transgenic mice Journal of Molecular and Cellular Cardiology. 42. DOI: 10.1016/J.Yjmcc.2007.03.595 |
0.305 |
|
| 2007 |
Leroy J, Abi-Gerges A, Richter W, Nikolaev VO, Engelhardt S, Lohse MJ, Conti M, Fischmeister R, Vandecasteele G. Role of PDE3 and PDE4 for β-adrenergic control of cAMP and ICa,L in adult rat ventricular myocytes Journal of Molecular and Cellular Cardiology. 42: S49. DOI: 10.1016/J.Yjmcc.2007.03.139 |
0.614 |
|
| 2006 |
Nikolaev VO, Bünemann M, Schmitteckert E, Lohse MJ, Engelhardt S. Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling. Circulation Research. 99: 1084-91. PMID 17038640 DOI: 10.1161/01.Res.0000250046.69918.D5 |
0.767 |
|
| 2006 |
Hein P, Rochais F, Hoffmann C, Dorsch S, Nikolaev VO, Engelhardt S, Berlot CH, Lohse MJ, Bünemann M. Gs activation is time-limiting in initiating receptor-mediated signaling. The Journal of Biological Chemistry. 281: 33345-51. PMID 16963443 DOI: 10.1074/Jbc.M606713200 |
0.732 |
|
| 2005 |
Engelhardt S. Beta-adrenergic receptors in heart failure. Heart Failure Clinics. 1: 183-91. PMID 17386845 DOI: 10.1016/J.Hfc.2005.04.005 |
0.414 |
|
| 2005 |
Buitrago M, Lorenz K, Maass AH, Oberdorf-Maass S, Keller U, Schmitteckert EM, Ivashchenko Y, Lohse MJ, Engelhardt S. The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophy. Nature Medicine. 11: 837-44. PMID 16025126 DOI: 10.1038/Nm1272 |
0.56 |
|
| 2005 |
Frambach T, Müller T, Freund S, Engelhardt S, Sütterlin M, Lohse MJ, Dietl J. Self-limitation of intravenous tocolysis with beta2-adrenergic agonists is mediated through receptor G protein uncoupling. The Journal of Clinical Endocrinology and Metabolism. 90: 2882-7. PMID 15728216 DOI: 10.1210/Jc.2004-1732 |
0.617 |
|
| 2005 |
Nikolaev VO, Gambaryan S, Engelhardt S, Walter U, Lohse MJ. Real-time monitoring of the PDE2 activity of live cells: hormone-stimulated cAMP hydrolysis is faster than hormone-stimulated cAMP synthesis. The Journal of Biological Chemistry. 280: 1716-9. PMID 15557342 DOI: 10.1074/Jbc.C400505200 |
0.645 |
|
| 2004 |
Otto C, Hein L, Brede M, Jahns R, Engelhardt S, Gröne HJ, Schütz G. Pulmonary hypertension and right heart failure in pituitary adenylate cyclase-activating polypeptide type I receptor-deficient mice. Circulation. 110: 3245-51. PMID 15520307 DOI: 10.1161/01.Cir.0000147235.53360.59 |
0.381 |
|
| 2004 |
Witte K, Engelhardt S, Janssen BJ, Lohse M, Lemmer B. Circadian and short-term regulation of blood pressure and heart rate in transgenic mice with cardiac overexpression of the beta1-adrenoceptor. Chronobiology International. 21: 205-16. PMID 15332342 DOI: 10.1081/Cbi-120037801 |
0.542 |
|
| 2004 |
Foerster K, Kaeferstein T, Groner F, Engelhardt S, Matthes J, Koch WJ, Lohse MJ, Herzig S. Calcium channel function and regulation in beta 1- and beta 2-adrenoceptor transgenic mice. Naunyn-Schmiedeberg's Archives of Pharmacology. 369: 490-5. PMID 15083268 DOI: 10.1007/S00210-004-0928-3 |
0.561 |
|
| 2004 |
Engelhardt S, Hein L, Dyachenkow V, Kranias EG, Isenberg G, Lohse MJ. Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation. Circulation. 109: 1154-60. PMID 14967726 DOI: 10.1161/01.Cir.0000117254.68497.39 |
0.589 |
|
| 2003 |
Gaussin V, Tomlinson JE, Depre C, Engelhardt S, Antos CL, Takagi G, Hein L, Topper JN, Liggett SB, Olson EN, Lohse MJ, Vatner SF, Vatner DE. Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy. Circulation. 108: 2926-33. PMID 14623810 DOI: 10.1161/01.Cir.0000101922.18151.7B |
0.621 |
|
| 2003 |
Lohse MJ, Engelhardt S, Eschenhagen T. What is the role of beta-adrenergic signaling in heart failure? Circulation Research. 93: 896-906. PMID 14615493 DOI: 10.1161/01.Res.0000102042.83024.Ca |
0.625 |
|
| 2003 |
Eigenthaler M, Engelhardt S, Schinke B, Kobsar A, Schmitteckert E, Gambaryan S, Engelhardt CM, Krenn V, Eliava M, Jarchau T, Lohse MJ, Walter U, Hein L. Disruption of cardiac Ena-VASP protein localization in intercalated disks causes dilated cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 285: H2471-81. PMID 12933343 DOI: 10.1152/Ajpheart.00362.2003 |
0.562 |
|
| 2003 |
Maack C, Böhm M, Vlaskin L, Dabew E, Lorenz K, Schäfers HJ, Lohse MJ, Engelhardt S. Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor. Circulation. 108: 348-53. PMID 12847069 DOI: 10.1161/01.Cir.0000080325.94345.8B |
0.607 |
|
| 2003 |
Spindler M, Engelhardt S, Niebler R, Wagner H, Hein L, Lohse MJ, Neubauer S. Alterations in the myocardial creatine kinase system precede the development of contractile dysfunction in beta(1)-adrenergic receptor transgenic mice. Journal of Molecular and Cellular Cardiology. 35: 389-97. PMID 12689818 DOI: 10.1016/S0022-2828(03)00015-4 |
0.617 |
|
| 2003 |
ENGELHARDT S, HEIN L, KRANIAS E, LOHSE M. 682 Phospholamban is critically involved in beta-adrenergic receptor induced cardiac hypertrophy and failure European Journal of Heart Failure Supplements. 2: 140-141. DOI: 10.1016/S1567-4215(03)90427-9 |
0.631 |
|
| 2002 |
Engelhardt S, Hein L, Keller U, Klämbt K, Lohse MJ. Inhibition of Na(+)-H(+) exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice. Circulation Research. 90: 814-9. PMID 11964375 DOI: 10.1161/01.Res.0000014966.97486.C0 |
0.64 |
|
| 2001 |
Lohse MJ, Engelhardt S. Protein kinase a transgenes: the many faces of cAMP. Circulation Research. 89: 938-40. PMID 11717148 DOI: 10.1161/Res.89.11.938 |
0.603 |
|
| 2001 |
Brede M, Hadamek K, Meinel L, Wiesmann F, Peters J, Engelhardt S, Simm A, Haase A, Lohse MJ, Hein L. Vascular hypertrophy and increased P70S6 kinase in mice lacking the angiotensin II AT(2) receptor. Circulation. 104: 2602-7. PMID 11714657 DOI: 10.1161/Hc4601.099401 |
0.552 |
|
| 2001 |
Engelhardt S, Boknik P, Keller U, Neumann J, Lohse MJ, Hein L. Early impairment of calcium handling and altered expression of junctin in hearts of mice overexpressing the beta1-adrenergic receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2718-20. PMID 11606476 DOI: 10.1096/Fj.01-0107Fje |
0.641 |
|
| 2001 |
Engelhardt S, Grimmer Y, Fan GH, Lohse MJ. Constitutive activity of the human beta(1)-adrenergic receptor in beta(1)-receptor transgenic mice. Molecular Pharmacology. 60: 712-7. PMID 11562432 |
0.568 |
|
| 2001 |
Wiesmann F, Ruff J, Engelhardt S, Hein L, Dienesch C, Leupold A, Illinger R, Frydrychowicz A, Hiller KH, Rommel E, Haase A, Lohse MJ, Neubauer S. Dobutamine-stress magnetic resonance microimaging in mice : acute changes of cardiac geometry and function in normal and failing murine hearts. Circulation Research. 88: 563-9. PMID 11282889 DOI: 10.1161/01.Res.88.6.563 |
0.564 |
|
| 2001 |
Kaumann AJ, Engelhardt S, Hein L, Molenaar P, Lohse M. Abolition of (-)-CGP 12177-evoked cardiostimulation in double β1/β2-adrenoceptor knockout mice. Obligatory role of β1-adrenoceptors for putative β4-adrenoceptor pharmacology Naunyn-Schmiedeberg's Archives of Pharmacology. 363: 87-93. PMID 11191841 DOI: 10.1007/S002100000336 |
0.571 |
|
| 2000 |
Engelhardt S, Lohse MJ. Determination of adrenergic receptor mRNAs by quantitative reverse transcriptase-polymerase chain reactions. Methods in Molecular Biology (Clifton, N.J.). 126: 155-68. PMID 10685408 DOI: 10.1385/1-59259-684-3:155 |
0.499 |
|
| 1999 |
Engelhardt S, Hein L, Wiesmann F, Lohse MJ. Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 7059-64. PMID 10359838 DOI: 10.1073/Pnas.96.12.7059 |
0.643 |
|
| 1997 |
Engelhardt S, Zieger W, Kassubek J, Michel MC, Lohse MJ, Brodde OE. Tocolytic therapy with fenoterol induces selective down-regulation of beta-adrenergic receptors in human myometrium. The Journal of Clinical Endocrinology and Metabolism. 82: 1235-42. PMID 9100601 DOI: 10.1210/Jcem.82.4.3885 |
0.599 |
|
| 1996 |
Lohse MJ, Engelhardt S, Danner S, Böhm M. Mechanisms of beta-adrenergic receptor desensitization: from molecular biology to heart failure. Basic Research in Cardiology. 91: 29-34. PMID 8957541 DOI: 10.1007/Bf00795359 |
0.616 |
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| 1996 |
Engelhardt S, Böhm M, Erdmann E, Lohse MJ. Analysis of beta-adrenergic receptor mRNA levels in human ventricular biopsy specimens by quantitative polymerase chain reactions: progressive reduction of beta 1-adrenergic receptor mRNA in heart failure. Journal of the American College of Cardiology. 27: 146-54. PMID 8522688 DOI: 10.1016/0735-1097(95)00425-4 |
0.561 |
|
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