| Year |
Citation |
Score |
| 2020 |
Ouyang B, Poon W, Zhang YN, Lin ZP, Kingston BR, Tavares AJ, Zhang Y, Chen J, Valic MS, Syed AM, MacMillan P, Couture-Senécal J, Zheng G, Chan WCW. The dose threshold for nanoparticle tumour delivery. Nature Materials. PMID 32778816 DOI: 10.1038/S41563-020-0755-Z |
0.326 |
|
| 2020 |
Pellow C, O'Reilly MA, Hynynen K, Zheng G, Goertz DE. Simultaneous Intravital Optical and Acoustic Monitoring of Ultrasound-Triggered Nanobubble Generation and Extravasation. Nano Letters. PMID 32374617 DOI: 10.1021/Acs.Nanolett.0C01310 |
0.386 |
|
| 2020 |
Charron D, Yousefalizadeh G, Buzza HH, Rajora MA, Chen J, Stamplecoskie KG, Zheng G. Photophysics of J-aggregating Porphyrin-lipid Photosensitizers in Liposomes-Impact of Lipid Saturation. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 32338515 DOI: 10.1021/Acs.Langmuir.0C00843 |
0.308 |
|
| 2020 |
Valic MS, Halim M, Schimmer P, Zheng G. Guidelines for the experimental design of pharmacokinetic studies with nanomaterials in preclinical animal models. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32278829 DOI: 10.1016/J.Jconrel.2020.04.002 |
0.303 |
|
| 2020 |
Gu X, Song Q, Zhang Q, Huang M, Zheng M, Chen J, Wei D, Chen J, Wei X, Chen H, Zheng G, Gao X. Clearance of two organic nanoparticles from the brain via the paravascular pathway. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32165238 DOI: 10.1016/J.Jconrel.2020.03.009 |
0.306 |
|
| 2020 |
Jiang G, Chen H, Huang J, Song Q, Chen Y, Gu X, Jiang Z, Huang Y, Lin Y, Feng J, Jiang J, Bao Y, Zheng G, Chen J, Chen H, et al. Tailored Lipoprotein-Like miRNA Delivery Nanostructure Suppresses Glioma Stemness and Drug Resistance through Receptor-Stimulated Macropinocytosis. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 1903290. PMID 32154087 DOI: 10.1002/Advs.201903290 |
0.312 |
|
| 2020 |
Choi V, Rajora M, Zheng G. Activating drugs with sound: Mechanisms behind sonodynamic therapy and the role of nanomedicine. Bioconjugate Chemistry. PMID 32129984 DOI: 10.1021/Acs.Bioconjchem.0C00029 |
0.313 |
|
| 2019 |
Dhaliwal A, Zheng G. Improving accessibility of EPR-insensitive tumor phenotypes using EPR-adaptive strategies: Designing a new perspective in nanomedicine delivery. Theranostics. 9: 8091-8108. PMID 31754383 DOI: 10.7150/Thno.37204 |
0.345 |
|
| 2019 |
Muhanna N, Chan H, Townson JL, Jin CS, Ding L, Valic M, Douglas CM, Maclaughlin CM, Chen J, Zheng G, Irish JC. Photodynamic therapy enables tumor specific ablation in preclinical models of thyroid cancer. Endocrine-Related Cancer. PMID 31751308 DOI: 10.1530/Erc-19-0258 |
0.326 |
|
| 2019 |
Overchuk M, Damen MPF, Harmatys KM, Pomper MG, Chen J, Zheng G. Long-Circulating Prostate-Specific Membrane Antigen-Targeted NIR Phototheranostic Agent. Photochemistry and Photobiology. PMID 31742696 DOI: 10.1111/Php.13181 |
0.372 |
|
| 2019 |
Hou W, Lou J, Bu J, Chang E, Ding L, Valic M, Jeon HH, Charron D, Coolens C, Cui D, Chen J, Zheng G. Nanoemulsion with Porphyrin Shell for Cancer Theranostics. Angewandte Chemie (International Ed. in English). PMID 31410962 DOI: 10.1002/Anie.201908664 |
0.374 |
|
| 2019 |
Cheng MHY, Harmatys KM, Charron D, Chen J, Zheng G. Stable J-aggregation of an aza-BODIPY-lipid in a liposome for optical cancer imaging. Angewandte Chemie (International Ed. in English). PMID 31344292 DOI: 10.1002/Anie.201907754 |
0.415 |
|
| 2019 |
Harmatys KM, Overchuk M, Zheng G. Rational Design of Photosynthesis-Inspired Nanomedicines. Accounts of Chemical Research. PMID 31021599 DOI: 10.1021/Acs.Accounts.9B00104 |
0.357 |
|
| 2019 |
Overchuk M, Zheng M, Rajora MA, Charron DM, Chen J, Zheng G. Tailoring Porphyrin Conjugation for Nanoassembly-Driven Phototheranostic Properties. Acs Nano. PMID 30916932 DOI: 10.1021/Acsnano.9B00494 |
0.401 |
|
| 2019 |
Kinoshita T, Ujiie H, Chen J, Ding L, Chan H, Gregor A, Bernards N, McVeigh PZ, Fujino K, Lee CY, Motooka Y, Inage T, Valic MS, Effat A, Weersink R, ... ... Zheng G, et al. Evaluation of novel imaging devices for nanoparticle-mediated fluorescence-guided lung tumor therapy. The Annals of Thoracic Surgery. PMID 30742818 DOI: 10.1016/J.Athoracsur.2019.01.008 |
0.387 |
|
| 2019 |
Valic MS, Jiang W, Ding L, Chen J, Lheureux S, Oza AM, Zheng G. Abstract 1947: Modelling of lipid-based nanoparticle pharmacokinetics and tumor accumulation using preclinical models of ovarian cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-1947 |
0.346 |
|
| 2018 |
Zheng G, Overchuk M. How nanomedicine can be used in the treatment of tumors: an interview with Dr Gang Zheng. Nanomedicine (London, England). PMID 30421644 DOI: 10.2217/Nnm-2018-0383 |
0.338 |
|
| 2018 |
Harmatys K, Overchuk M, Chen J, Ding L, Chen Y, Pomper MG, Zheng G. Tuning Pharmacokinetics to Improve Tumor Accumulation of a PSMA-Targeted Phototheranostic Agent. Bioconjugate Chemistry. PMID 30350576 DOI: 10.1021/Acs.Bioconjchem.8B00636 |
0.372 |
|
| 2018 |
Ujiie H, Ding L, Fan R, Kato T, Lee D, Fujino K, Kinoshita T, Lee CY, Waddell TK, Keshavjee S, Wilson BC, Zheng G, Chen J, Yasufuku K. PorphyrinHDL: A Novel Photosensitizing Nanoparticle for Lung Cancer Therapy. The Annals of Thoracic Surgery. PMID 30316853 DOI: 10.1016/J.Athoracsur.2018.08.053 |
0.364 |
|
| 2018 |
Kato T, Jin CS, Lee D, Ujiie H, Fujino K, Hu HP, Wada H, Wu L, Chen J, Weersink RA, Kanno H, Hatanaka Y, Hatanaka KC, Kaga K, Matsui Y, ... ... Zheng G, et al. Preclinical investigation of folate receptor-targeted nanoparticles for photodynamic therapy of malignant pleural mesothelioma. International Journal of Oncology. PMID 30226590 DOI: 10.3892/Ijo.2018.4555 |
0.349 |
|
| 2018 |
Keca JM, Valic MS, Cheng MHY, Jiang W, Overchuk M, Chen J, Zheng G. Mixed and Matched Metallo-Nanotexaphyrin for Customizable Biomedical Imaging. Advanced Healthcare Materials. e1800857. PMID 30211482 DOI: 10.1002/Adhm.201800857 |
0.379 |
|
| 2018 |
Luby BM, Walsh CD, Zheng G. Advanced photosensitizer activation strategies for smarter photodynamic therapy beacons. Angewandte Chemie (International Ed. in English). PMID 29890024 DOI: 10.1002/Anie.201805246 |
0.317 |
|
| 2018 |
Harmatys K, Chen J, Charron D, MacLaughlin C, Zheng G. Multi-Pronged Biomimetic Approach to Create Optically Tunable Nanoparticles. Angewandte Chemie (International Ed. in English). PMID 29752766 DOI: 10.1002/Anie.201803535 |
0.35 |
|
| 2018 |
Overchuk M, Zheng G. Overcoming obstacles in the tumor microenvironment: Recent advancements in nanoparticle delivery for cancer theranostics. Biomaterials. 156: 217-237. PMID 29207323 DOI: 10.1016/J.Biomaterials.2017.10.024 |
0.372 |
|
| 2018 |
Charron DM, Zheng G. Nanomedicine development guided by FRET imaging Nano Today. 18: 124-136. DOI: 10.1016/J.Nantod.2017.12.006 |
0.352 |
|
| 2018 |
Kato T, Jin C, Ujiie H, Fujino K, Lee D, Wada H, Hu H, Wu L, Weersink R, Chen J, Kanno H, Hatanaka Y, Hatanaka K, Matsuno Y, De Perrot M, ... ... Zheng G, et al. MA12.09 Preclinical Investigations of Folate Receptor Targeted Nanoparticles for Photodynamic Therapy of Malignant Pleural Mesothelioma Journal of Thoracic Oncology. 13: S398-S399. DOI: 10.1016/J.Jtho.2018.08.418 |
0.325 |
|
| 2017 |
Rajora MA, Ding L, Valic M, Jiang W, Overchuk M, Chen J, Zheng G. Correction: Tailored theranostic apolipoprotein E3 porphyrin-lipid nanoparticles target glioblastoma. Chemical Science. 8: 5803. PMID 30294416 DOI: 10.1039/C7Sc90047C |
0.318 |
|
| 2017 |
Tavares AJ, Poon W, Zhang YN, Dai Q, Besla R, Ding D, Ouyang B, Li A, Chen J, Zheng G, Robbins C, Chan WCW. Effect of removing Kupffer cells on nanoparticle tumor delivery. Proceedings of the National Academy of Sciences of the United States of America. PMID 29208719 DOI: 10.1073/Pnas.1713390114 |
0.373 |
|
| 2017 |
Pellow C, Goertz DE, Zheng G. Breaking free from vascular confinement: status and prospects for submicron ultrasound contrast agents. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. PMID 29148219 DOI: 10.1002/Wnan.1502 |
0.308 |
|
| 2017 |
Kato T, Jin CS, Ujiie H, Lee D, Fujino K, Wada H, Hu HP, Weersink RA, Chen J, Kaji M, Kaga K, Matsui Y, Wilson BC, Zheng G, Yasufuku K. Nanoparticle targeted folate receptor 1-enhanced photodynamic therapy for lung cancer. Lung Cancer (Amsterdam, Netherlands). 113: 59-68. PMID 29110850 DOI: 10.1016/J.Lungcan.2017.09.002 |
0.321 |
|
| 2017 |
Rajora MA, Lou JWH, Zheng G. Advancing porphyrin's biomedical utility via supramolecular chemistry. Chemical Society Reviews. PMID 29048439 DOI: 10.1039/C7Cs00525C |
0.347 |
|
| 2017 |
Kato T, Lee D, Huang H, Cruz-Munoz W, Ujiie H, Fujino K, Wada H, Patel P, Hu HP, Hirohashi K, Nakajima T, Sato M, Kaji M, Kaga K, Matsui Y, ... ... Zheng G, et al. Personalized siRNA-nanoparticle Systemic Therapy using Metastatic Lymph Node Specimens Obtained with EBUS-TBNA in Lung Cancer. Molecular Cancer Research : McR. PMID 28993508 DOI: 10.1158/1541-7786.Mcr-16-0341 |
0.35 |
|
| 2017 |
Rajora MA, Ding L, Valic M, Jiang W, Overchuk M, Chen J, Zheng G. Tailored theranostic apolipoprotein E3 porphyrin-lipid nanoparticles target glioblastoma. Chemical Science. 8: 5371-5384. PMID 28970916 DOI: 10.1039/C7Sc00732A |
0.387 |
|
| 2017 |
Luby B, Zheng G. Specific, direct amplified microRNA detection with microRNA:Argonaute-2 cleavage (miRACle) beacons. Angewandte Chemie (International Ed. in English). PMID 28871632 DOI: 10.1002/Anie.201707366 |
0.314 |
|
| 2017 |
Colombo I, Overchuk M, Chen J, Reilly RM, Zheng G, Lheureux S. Molecular imaging in drug development: update and challenges for radiolabeled antibodies and nanotechnology. Methods (San Diego, Calif.). PMID 28743635 DOI: 10.1016/J.Ymeth.2017.07.018 |
0.374 |
|
| 2017 |
Lim L, Mastragostino R, Ng K, Zheng G, Wilson BC. Can photoacoustic imaging quantify surface-localized J-aggregating nanoparticles? Journal of Biomedical Optics. 22: 76008. PMID 28703256 DOI: 10.1117/1.Jbo.22.7.076008 |
0.563 |
|
| 2017 |
Kato T, Jin C, Ujiie H, Lee D, Kosuke F, Wada H, Hu H, Weersink R, Chen J, Kaji M, Wilson B, Zheng G, Kaga K, Matsui Y, Yasufuku K. P1.12-002 Nanoparticle Targeted Folate Receptor 1 Enhanced Photodynamic Therapy for Lung Cancer Journal of Thoracic Oncology. 12: S2028. DOI: 10.1016/J.Jtho.2017.09.1000 |
0.32 |
|
| 2017 |
Keca JM, Zheng G. Texaphyrin: From molecule to nanoparticle Coordination Chemistry Reviews. 379: 133-146. DOI: 10.1016/J.Ccr.2017.08.026 |
0.307 |
|
| 2016 |
Rajora MA, Zheng G. Targeting SR-BI for Cancer Diagnostics, Imaging and Therapy. Frontiers in Pharmacology. 7: 326. PMID 27729859 DOI: 10.3389/Fphar.2016.00326 |
0.359 |
|
| 2016 |
Luby BM, Charron DM, MacLaughlin CM, Zheng G. Activatable fluorescence: From small molecule to nanoparticle. Advanced Drug Delivery Reviews. PMID 27593264 DOI: 10.1016/J.Addr.2016.08.010 |
0.384 |
|
| 2016 |
MacLaughlin CM, Ding L, Jin C, Cao P, Siddiqui I, Hwang DM, Chen J, Wilson BC, Zheng G, Hedley DW. Porphysome nanoparticles for enhanced photothermal therapy in a patient-derived orthotopic pancreas xenograft cancer model: a pilot study. Journal of Biomedical Optics. 21: 84002. PMID 27552306 DOI: 10.1117/1.Jbo.21.8.084002 |
0.391 |
|
| 2016 |
Yasufuku K, Jin CS, Wada H, Anayama T, McVeigh PZ, Hu HP, Hirohashi K, Nakajima T, Kato T, Keshavjee S, Hwang D, Wilson BC, Zheng G. An integrated nanotechnology-enabled transbronchial image-guided intervention strategy for peripheral lung cancer. Cancer Research. PMID 27543602 DOI: 10.1158/0008-5472.Can-15-3196 |
0.338 |
|
| 2016 |
Ng KK, Weersink RA, Lim L, Wilson BC, Zheng G. Controlling Spatial Heat and Light Distribution by Using Photothermal Enhancing Auto-Regulated Liposomes (PEARLs). Angewandte Chemie (International Ed. in English). PMID 27411830 DOI: 10.1002/Anie.201605241 |
0.561 |
|
| 2016 |
Valic MS, Zheng G. Rethinking translational nanomedicine: insights from the 'bottom-up' design of the Porphysome for guiding the clinical development of imageable nanomaterials. Current Opinion in Chemical Biology. 33: 126-134. PMID 27352246 DOI: 10.1016/J.Cbpa.2016.06.015 |
0.314 |
|
| 2016 |
Lin Q, Huang H, Chen J, Zheng G. Using Fluorescence Imaging to Track Drug Delivery and Guide Treatment Planning In Vivo. Methods in Molecular Biology (Clifton, N.J.). 1444: 153-66. PMID 27283425 DOI: 10.1007/978-1-4939-3721-9_14 |
0.371 |
|
| 2016 |
Burgess L, Chen J, Wolter NE, Wilson B, Zheng G. Topical MMP beacon enabled fluorescence-guided resection of oral carcinoma. Biomedical Optics Express. 7: 1089-99. PMID 27231609 DOI: 10.1364/Boe.7.001089 |
0.323 |
|
| 2016 |
Jin CS, Overchuk M, Cui L, Wilson BC, Bristow RG, Chen J, Zheng G. Nanoparticle-enabled selective destruction of prostate tumor using MRI-guided focal photothermal therapy. The Prostate. PMID 27198587 DOI: 10.1002/Pros.23203 |
0.345 |
|
| 2016 |
Keca JM, Chen J, Overchuk M, Muhanna N, MacLaughlin CM, Jin CS, Foltz WD, Irish JC, Zheng G. Nanotexaphyrin: One-Pot Synthesis of a Manganese Texaphyrin-Phospholipid Nanoparticle for Magnetic Resonance Imaging. Angewandte Chemie (International Ed. in English). PMID 27071806 DOI: 10.1002/Anie.201600234 |
0.34 |
|
| 2016 |
Ng KK, Takada M, Harmatys K, Chen J, Zheng G. Chlorosome-Inspired Synthesis of Templated Metallochlorin-Lipid Nanoassemblies for Biomedical Applications. Acs Nano. PMID 27015124 DOI: 10.1021/Acsnano.5B07151 |
0.548 |
|
| 2016 |
Huynh E, Rajora MA, Zheng G. Multimodal micro, nano, and size conversion ultrasound agents for imaging and therapy. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. PMID 27006001 DOI: 10.1002/Wnan.1398 |
0.33 |
|
| 2016 |
Sykes EA, Dai Q, Sarsons CD, Chen J, Rocheleau JV, Hwang DM, Zheng G, Cramb DT, Rinker KD, Chan WC. Tailoring nanoparticle designs to target cancer based on tumor pathophysiology. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884153 DOI: 10.1073/Pnas.1521265113 |
0.362 |
|
| 2016 |
Liu TW, Akens MK, Chen J, Wilson BC, Zheng G. Matrix metalloproteinase-based photodynamic molecular beacons for targeted destruction of bone metastases in vivo. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. PMID 26880165 DOI: 10.1039/C5Pp00414D |
0.303 |
|
| 2016 |
Shakiba M, Ng KK, Huynh E, Chan H, Charron DM, Chen J, Muhanna N, Foster FS, Wilson BC, Zheng G. Stable J-aggregation enabled dual photoacoustic and fluorescence nanoparticles for intraoperative cancer imaging. Nanoscale. PMID 26731304 DOI: 10.1039/C5Nr08165C |
0.579 |
|
| 2016 |
MacLaughlin CM, Ding L, Jin C, Cao P, Siddiqui I, Hwang DM, Chen J, Wilson BC, Zheng G, Hedley DW. Porphyrin lipid nanoparticles for enhanced photothermal therapy in a patient-derived orthotopic pancreas xenograft cancer model Proceedings of Spie. 9696. DOI: 10.1117/12.2214882 |
0.413 |
|
| 2015 |
Muhanna N, MacDonald TD, Chan H, Jin CS, Burgess L, Cui L, Chen J, Irish JC, Zheng G. Porphysomes: Multimodal Nanoparticle for Primary Tumor Delineation and Lymphatic Metastasis Mapping in a Head-and-Neck Cancer Rabbit Model (Adv. Healthcare Mater. 14/2015). Advanced Healthcare Materials. 4: 2163. PMID 29896901 DOI: 10.1002/Adhm.201570084 |
0.334 |
|
| 2015 |
Muhanna N, Jin CS, Huynh E, Chan H, Qiu Y, Jiang W, Cui L, Burgess L, Akens MK, Chen J, Irish JC, Zheng G. Phototheranostic Porphyrin Nanoparticles Enable Visualization and Targeted Treatment of Head and Neck Cancer in Clinically Relevant Models. Theranostics. 5: 1428-43. PMID 26681987 DOI: 10.7150/Thno.13451 |
0.371 |
|
| 2015 |
Paproski RJ, Forbrich A, Huynh E, Chen J, Lewis JD, Zheng G, Zemp RJ. Porphyrin Nanodroplets: Sub-micrometer Ultrasound and Photoacoustic Contrast Imaging Agents. Small (Weinheim An Der Bergstrasse, Germany). PMID 26633744 DOI: 10.1002/Smll.201502450 |
0.37 |
|
| 2015 |
Muhanna N, Cui L, Chan H, Burgess L, Jin CS, MacDonald TD, Huynh E, Wang F, Chen J, Irish JC, Zheng G. Multimodal Image-Guided Surgical and Photodynamic Interventions in Head-and-Neck Cancer: From Primary Tumor to Metastatic Drainage. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26463705 DOI: 10.1158/1078-0432.Ccr-15-1235 |
0.336 |
|
| 2015 |
Cui L, Tokarz D, Cisek R, Ng KK, Wang F, Chen J, Barzda V, Zheng G. Organized Aggregation of Porphyrins in Lipid Bilayer for Third Harmonic Generation Microscopy. Angewandte Chemie (International Ed. in English). PMID 26418395 DOI: 10.1002/Anie.201506171 |
0.576 |
|
| 2015 |
Muhanna N, MacDonald TD, Chan H, Jin CS, Burgess L, Cui L, Chen J, Irish JC, Zheng G. Multimodal Nanoparticle for Primary Tumor Delineation and Lymphatic Metastasis Mapping in a Head-and-Neck Cancer Rabbit Model. Advanced Healthcare Materials. PMID 26283596 DOI: 10.1002/Adhm.201500363 |
0.337 |
|
| 2015 |
Ng KK, Zheng G. Molecular Interactions in Organic Nanoparticles for Phototheranostic Applications. Chemical Reviews. PMID 26244706 DOI: 10.1021/Acs.Chemrev.5B00140 |
0.52 |
|
| 2015 |
Huynh E, Zheng G. Cancer nanomedicine: addressing the dark side of the enhanced permeability and retention effect. Nanomedicine (London, England). 10: 1993-5. PMID 26096565 DOI: 10.2217/Nnm.15.86 |
0.339 |
|
| 2015 |
Charron DM, Chen J, Zheng G. Theranostic lipid nanoparticles for cancer medicine. Cancer Treatment and Research. 166: 103-27. PMID 25895866 DOI: 10.1007/978-3-319-16555-4_5 |
0.368 |
|
| 2015 |
Cui L, Lin Q, Jin CS, Jiang W, Huang H, Ding L, Muhanna N, Irish JC, Wang F, Chen J, Zheng G. A PEGylation-Free Biomimetic Porphyrin Nanoplatform for Personalized Cancer Theranostics. Acs Nano. 9: 4484-95. PMID 25830219 DOI: 10.1021/Acsnano.5B01077 |
0.423 |
|
| 2015 |
Huynh E, Leung BY, Helfield BL, Shakiba M, Gandier JA, Jin CS, Master ER, Wilson BC, Goertz DE, Zheng G. In situ conversion of porphyrin microbubbles to nanoparticles for multimodality imaging. Nature Nanotechnology. 10: 325-32. PMID 25822929 DOI: 10.1038/Nnano.2015.25 |
0.377 |
|
| 2015 |
Farhadi A, Roxin Á, Wilson BC, Zheng G. Nano-enabled SERS reporting photosensitizers. Theranostics. 5: 469-76. PMID 25767614 DOI: 10.7150/Thno.10694 |
0.697 |
|
| 2015 |
Ng KK, Takada M, Jin CC, Zheng G. Self-sensing porphysomes for fluorescence-guided photothermal therapy. Bioconjugate Chemistry. 26: 345-51. PMID 25563975 DOI: 10.1021/Bc500595D |
0.578 |
|
| 2015 |
Huang H, Cruz W, Chen J, Zheng G. Learning from biology: synthetic lipoproteins for drug delivery. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 7: 298-314. PMID 25346461 DOI: 10.1002/Wnan.1308 |
0.392 |
|
| 2014 |
Maeda A, Bu J, Chen J, Zheng G, DaCosta RS. Dual in vivo photoacoustic and fluorescence imaging of HER2 expression in breast tumors for diagnosis, margin assessment, and surgical guidance. Molecular Imaging. 13. PMID 25430722 DOI: 10.2310/7290.2014.00043 |
0.362 |
|
| 2014 |
Ng KK, Shakiba M, Huynh E, Weersink RA, Roxin Á, Wilson BC, Zheng G. Stimuli-responsive photoacoustic nanoswitch for in vivo sensing applications. Acs Nano. 8: 8363-73. PMID 25046406 DOI: 10.1021/Nn502858B |
0.737 |
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| 2014 |
MacDonald TD, Liu TW, Zheng G. An MRI-sensitive, non-photobleachable porphysome photothermal agent. Angewandte Chemie (International Ed. in English). 53: 6956-9. PMID 24840234 DOI: 10.1002/Anie.201400133 |
0.332 |
|
| 2014 |
Sykes EA, Chen J, Zheng G, Chan WC. Investigating the impact of nanoparticle size on active and passive tumor targeting efficiency. Acs Nano. 8: 5696-706. PMID 24821383 DOI: 10.1021/Nn500299P |
0.369 |
|
| 2014 |
Nakajima T, Anayama T, Matsuda Y, Hwang DM, McVeigh PZ, Wilson BC, Zheng G, Keshavjee S, Yasufuku K. Orthotopic lung cancer murine model by nonoperative transbronchial approach. The Annals of Thoracic Surgery. 97: 1771-5. PMID 24792261 DOI: 10.1016/J.Athoracsur.2014.01.048 |
0.305 |
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| 2014 |
Luby BM, Farhadi A, Shakiba M, Charron DM, Roxin A, Zheng G. Research Highlights: highlights from the latest articles in nanomedicine. Nanomedicine (London, England). 9: 385-8. PMID 24787437 DOI: 10.2217/Nnm.13.216 |
0.618 |
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| 2014 |
Lin Q, Jin CS, Huang H, Ding L, Zhang Z, Chen J, Zheng G. Nanoparticle-enabled, image-guided treatment planning of target specific RNAi therapeutics in an orthotopic prostate cancer model. Small (Weinheim An Der Bergstrasse, Germany). 10: 3072-82. PMID 24706435 DOI: 10.1002/Smll.201303842 |
0.426 |
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| 2014 |
Huynh E, Jin CS, Wilson BC, Zheng G. Aggregate enhanced trimodal porphyrin shell microbubbles for ultrasound, photoacoustic, and fluorescence imaging. Bioconjugate Chemistry. 25: 796-801. PMID 24621279 DOI: 10.1021/bc5000725 |
0.383 |
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| 2014 |
Jin CS, Cui L, Wang F, Chen J, Zheng G. Targeting-triggered porphysome nanostructure disruption for activatable photodynamic therapy. Advanced Healthcare Materials. 3: 1240-9. PMID 24464930 DOI: 10.1002/Adhm.201300651 |
0.352 |
|
| 2014 |
Yao L, Song Q, Bai W, Zhang J, Miao D, Jiang M, Wang Y, Shen Z, Hu Q, Gu X, Huang M, Zheng G, Gao X, Hu B, Chen J, et al. Facilitated brain delivery of poly (ethylene glycol)-poly (lactic acid) nanoparticles by microbubble-enhanced unfocused ultrasound. Biomaterials. 35: 3384-95. PMID 24447462 DOI: 10.1016/J.Biomaterials.2013.12.043 |
0.326 |
|
| 2014 |
Jeon M, Song W, Huynh E, Kim J, Kim J, Helfield BL, Leung BY, Goertz DE, Zheng G, Oh J, Lovell JF, Kim C. Methylene blue microbubbles as a model dual-modality contrast agent for ultrasound and activatable photoacoustic imaging. Journal of Biomedical Optics. 19: 16005. PMID 24390438 DOI: 10.1117/1.Jbo.19.1.016005 |
0.538 |
|
| 2014 |
Huynh E, Lovell JF, Fobel R, Zheng G. Optically controlled pore formation in self-sealing giant porphyrin vesicles. Small (Weinheim An Der Bergstrasse, Germany). 10: 1184-93. PMID 24376046 DOI: 10.1002/Smll.201302424 |
0.515 |
|
| 2014 |
Lin Q, Chen J, Zhang Z, Zheng G. Lipid-based nanoparticles in the systemic delivery of siRNA. Nanomedicine (London, England). 9: 105-20. PMID 24354813 DOI: 10.2217/Nnm.13.192 |
0.352 |
|
| 2014 |
Lanza GM, Moonen C, Baker JR, Chang E, Cheng Z, Grodzinski P, Ferrara K, Hynynen K, Kelloff G, Lee YE, Patri AK, Sept D, Schnitzer JE, Wood BJ, Zhang M, ... Zheng G, et al. Assessing the barriers to image-guided drug delivery. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 6: 1-14. PMID 24339356 DOI: 10.1002/Wnan.1247 |
0.344 |
|
| 2014 |
Roxin Ã, Chen J, Paton AS, Bender TP, Zheng G. Modulation of reactive oxygen species photogeneration of bacteriopheophorbide a derivatives by exocyclic E-ring opening and charge modifications. Journal of Medicinal Chemistry. 57: 223-37. PMID 24328124 DOI: 10.1021/Jm401538H |
0.645 |
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| 2014 |
Moriyama EH, Cao W, Liu TW, Wang HL, Kim PD, Chen J, Zheng G, Wilson BC. Optical glucose analogs of aminolevulinic acid for fluorescence-guided tumor resection and photodynamic therapy. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 495-503. PMID 24323192 DOI: 10.1007/S11307-013-0687-Y |
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Lin Q, Chen J, Ng KK, Cao W, Zhang Z, Zheng G. Imaging the cytosolic drug delivery mechanism of HDL-like nanoparticles. Pharmaceutical Research. 31: 1438-49. PMID 23625096 DOI: 10.1007/S11095-013-1046-Z |
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MacDonald TD, Zheng G. Porphysome nanoparticles: Tailoring treatments with nature’s pigments Photonics & Lasers in Medicine. 3. DOI: 10.1515/Plm-2013-0059 |
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Ng K, Shakiba M, Huynh E, Weersink R, Wilson B, Zheng G. Temperature-switched ordered dye embedded nanoparticles for focal thermal therapy response measurements Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2014.Bw1B.2 |
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Cui L, Lin Q, Jiang W, Ding L, Chen J, Zheng G. Porphyrin-lipid assembled HDL-like nanovesicles for fluorescence imaging and PDT treatment of orthotopic brain glioma tumor Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2014.Bt3A.55 |
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Roxin A, MacDonald TD, Zheng G. Synthesis and characterization of a new natural product analog, 13 2-173-bacteriochlorophyllone a Journal of Porphyrins and Phthalocyanines. 18: 188-199. DOI: 10.1142/S1088424613501058 |
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Huynh E, Zheng G. Organic Biophotonic Nanoparticles: Porphysomes and Beyond Ieee Journal of Selected Topics in Quantum Electronics. 20: 27-34. DOI: 10.1109/Jstqe.2013.2289971 |
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Huynh E, Zheng G. Porphysome nanotechnology: A paradigm shift in lipid-based supramolecular structures Nano Today. 9: 212-222. DOI: 10.1016/J.Nantod.2014.04.012 |
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Jin CS, Lovell JF, Zheng G. One minute, sub-one-watt photothermal tumor ablation using porphysomes, intrinsic multifunctional nanovesicles. Journal of Visualized Experiments : Jove. e50536. PMID 24084712 DOI: 10.3791/50536 |
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Liu TW, Stewart JM, Macdonald TD, Chen J, Clarke B, Shi J, Wilson BC, Neel BG, Zheng G. Biologically-targeted detection of primary and micro-metastatic ovarian cancer. Theranostics. 3: 420-7. PMID 23781288 DOI: 10.7150/Thno.6413 |
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Liu TW, Macdonald TD, Jin CS, Gold JM, Bristow RG, Wilson BC, Zheng G. Inherently multimodal nanoparticle-driven tracking and real-time delineation of orthotopic prostate tumors and micrometastases. Acs Nano. 7: 4221-32. PMID 23544841 DOI: 10.1021/Nn400669R |
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Xu HN, Zheng G, Tchou J, Nioka S, Li LZ. Characterizing the metabolic heterogeneity in human breast cancer xenografts by 3D high resolution fluorescence imaging. Springerplus. 2: 73. PMID 23543813 DOI: 10.1186/2193-1801-2-73 |
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Ng KK, Lovell JF, Vedadi A, Hajian T, Zheng G. Self-assembled porphyrin nanodiscs with structure-dependent activation for phototherapy and photodiagnostic applications. Acs Nano. 7: 3484-90. PMID 23464857 DOI: 10.1021/Nn400418Y |
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Huynh E, Zheng G. Engineering multifunctional nanoparticles: all-in-one versus one-for-all. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 5: 250-65. PMID 23450626 DOI: 10.1002/Wnan.1217 |
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Jin CS, Lovell JF, Chen J, Zheng G. Ablation of hypoxic tumors with dose-equivalent photothermal, but not photodynamic, therapy using a nanostructured porphyrin assembly. Acs Nano. 7: 2541-50. PMID 23394589 DOI: 10.1021/Nn3058642 |
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Corbin IR, Ng KK, Ding L, Jurisicova A, Zheng G. Near-infrared fluorescent imaging of metastatic ovarian cancer using folate receptor-targeted high-density lipoprotein nanocarriers. Nanomedicine (London, England). 8: 875-90. PMID 23067398 DOI: 10.2217/Nnm.12.137 |
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Lakshman M, Bu J, Maeda A, Zheng G, Needles A, Theodoropoulos C, Costa RD. Abstract 720: A validation study on photoacoustics imaging of fluorescent pyroporphysomein vivo. Cancer Research. 73: 720-720. DOI: 10.1158/1538-7445.Am2013-720 |
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Liu TW, MacDonald TD, Jin CS, Gold JM, Bristow RG, Wilson BC, Zheng G. Correction to Inherently Multimodal Nanoparticle-Driven Tracking and Real-Time Delineation of Orthotopic Prostate Tumors and Micrometastases Acs Nano. 7: 4691-4691. DOI: 10.1021/Nn401788G |
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McKee TD, Chen J, Corbin I, Zheng G, Khokha R. QUANTIFYING NANOPARTICLE TRANSPORT IN VIVO USING HYPERSPECTRAL IMAGING WITH A DORSAL SKINFOLD WINDOW CHAMBER. Journal of Innovative Optical Health Sciences. 5. PMID 28855967 DOI: 10.1142/S179354581250023X |
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Liu TW, MacDonald TD, Shi J, Wilson BC, Zheng G. Intrinsically copper-64-labeled organic nanoparticles as radiotracers. Angewandte Chemie (International Ed. in English). 51: 13128-31. PMID 23154923 DOI: 10.1002/Anie.201206939 |
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Roxin Ã, Zheng G. Flexible or fixed: a comparative review of linear and cyclic cancer-targeting peptides. Future Medicinal Chemistry. 4: 1601-18. PMID 22917248 DOI: 10.4155/Fmc.12.75 |
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Lin Q, Chen J, Jin H, Ng KK, Yang M, Cao W, Ding L, Zhang Z, Zheng G. Efficient systemic delivery of siRNA by using high-density lipoprotein-mimicking peptide lipid nanoparticles. Nanomedicine (London, England). 7: 1813-25. PMID 22830501 DOI: 10.2217/Nnm.12.73 |
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Huynh E, Lovell JF, Helfield BL, Jeon M, Kim C, Goertz DE, Wilson BC, Zheng G. Porphyrin shell microbubbles with intrinsic ultrasound and photoacoustic properties. Journal of the American Chemical Society. 134: 16464-7. PMID 22827774 DOI: 10.1021/Ja305988F |
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Roxin Ã, Chen J, Scully CC, Rotstein BH, Yudin AK, Zheng G. Conformational modulation of in vitro activity of cyclic RGD peptides via aziridine aldehyde-driven macrocyclization chemistry. Bioconjugate Chemistry. 23: 1387-95. PMID 22709546 DOI: 10.1021/Bc300239A |
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Lovell JF, Jin CS, Huynh E, MacDonald TD, Cao W, Zheng G. Enzymatic regioselection for the synthesis and biodegradation of porphysome nanovesicles. Angewandte Chemie (International Ed. in English). 51: 2429-33. PMID 22267090 DOI: 10.1002/Anie.201108280 |
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Xu HN, Zheng G, Nioka S, Chance B, Li LZ. High-resolution simultaneous mapping of mitochondrial redox state and glucose uptake in human breast tumor xenografts. Advances in Experimental Medicine and Biology. 737: 175-9. PMID 22259099 DOI: 10.1007/978-1-4614-1566-4_26 |
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Jin H, Lovell JF, Chen J, Lin Q, Ding L, Ng KK, Pandey RK, Manoharan M, Zhang Z, Zheng G. Mechanistic insights into LDL nanoparticle-mediated siRNA delivery. Bioconjugate Chemistry. 23: 33-41. PMID 22142191 DOI: 10.1021/Bc200233N |
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Jin CS, Zheng G. Liposomal nanostructures for photosensitizer delivery. Lasers in Surgery and Medicine. 43: 734-48. PMID 22057501 DOI: 10.1002/Lsm.21101 |
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Bawa R, Fung SY, Shiozaki A, Yang H, Zheng G, Keshavjee S, Liu M. Self-assembling peptide-based nanoparticles enhance cellular delivery of the hydrophobic anticancer drug ellipticine through caveolae-dependent endocytosis. Nanomedicine : Nanotechnology, Biology, and Medicine. 8: 647-54. PMID 21889478 DOI: 10.1016/J.Nano.2011.08.007 |
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Anayama T, McVeigh P, Jin C, Nakajima T, Wilson B, Zheng G, Keshavjee S, Yasufuku K. Bronchoscopic Detection of Lung Cancer With Porphysome Nanoparticle-Based Contrast Enhancement and a Prototype Fluorescent Bronchoscope Chest. 142: 926. DOI: 10.1378/Chest.1389685 |
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Jin CS, Lovell JF, Zheng G. Porphysomes: Multifunctional Nanovesicles to Treat Hypoxic Tumour by Photothermal Therapy Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2012.Bsu3A.9 |
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Liu TW, Akens MK, Chen J, Wise-Milestone L, Wilson BC, Zheng G. Photodynamic molecular beacons: An image -guided therapeutic approach for vertebral metastases. Biomedical Optics. DOI: 10.1364/Biomed.2012.Bsu3A.83 |
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Huynh E, Lovell JF, Zheng G. Optically Controlled Opening of Self-Sealing Giant Unilamellar Vesicles Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2012.Bsu3A.8 |
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Huynh E, Lovell JF, Helfield B, Kim C, Goertz DE, Zheng G. Generation of Photonic Shell Microbubbles Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2012.Bsu3A.55 |
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Lin Q, Chen J, Zhang Z, Zheng G. In vivo near infrared fluorescence imaging of efficient systemic siRNA delivery with HDL-mimicking peptide lipid nanoparticles Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2012.Bsu3A.3 |
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Lin Q, Chen J, Zhang Z, Zheng G. Study on the Cytosolic delivery mechanism of HDL-mimicking Peptide-Phospholipid Scaffold (HPPS) By Confocal Microscopy Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2012.Bsu3A.12 |
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Jin CS, Lovell JF, Zheng G. Porphysomes: Intrinsically Multifunctional Nanovesicles for Photothermal Therapy Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2012.Bm2A.5 |
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Jin H, Chen J, Lovell JF, Zhang Z, Zheng G. Synthesis and development of lipoprotein-based nanocarriers for light-activated theranostics Israel Journal of Chemistry. 52: 715-727. DOI: 10.1002/Ijch.201100054 |
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Mawn TM, Popov AV, Beardsley NJ, Stefflova K, Milkevitch M, Zheng G, Delikatny EJ. In vivo detection of phospholipase C by enzyme-activated near-infrared probes. Bioconjugate Chemistry. 22: 2434-43. PMID 22034913 DOI: 10.1021/Bc200242V |
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Lovell JF, Huynh E, MacDonald TD, Lin Q, Zheng G. A new endogenous and immunologically inert siRNA delivery vehicle for targeting the brain. Nanomedicine (London, England). 6: 1157-8. PMID 22029061 |
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Lovell JF, Huynh E, MacDonald TD, Lin Q, Zheng G. A challenger appears: a copper nanocolloid for MR detection of atherosclerotic plaques. Nanomedicine (London, England). 6: 1157. PMID 22029060 |
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Lovell JF, Huynh E, MacDonald TD, Lin Q, Zheng G. Bursting the bubble: microbubble–nanoparticle composites for ultrasound-mediated drug delivery. Nanomedicine (London, England). 6: 1156-7. PMID 22029059 |
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Lovell JF, Huynh E, MacDonald TD, Lin Q, Zheng G. Downsizing nanoparticles for better tumor penetration and accumulation. Nanomedicine (London, England). 6: 1156. PMID 22029058 |
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Lovell JF, Chan MW, Qi Q, Chen J, Zheng G. Porphyrin FRET acceptors for apoptosis induction and monitoring. Journal of the American Chemical Society. 133: 18580-2. PMID 22026412 DOI: 10.1021/Ja2083569 |
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Shi J, Liu TW, Chen J, Green D, Jaffray D, Wilson BC, Wang F, Zheng G. Transforming a Targeted Porphyrin Theranostic Agent into a PET Imaging Probe for Cancer. Theranostics. 1: 363-70. PMID 21938264 DOI: 10.7150/Thno/V01P0363 |
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Liu TW, Chen J, Burgess L, Cao W, Shi J, Wilson BC, Zheng G. Multimodal bacteriochlorophyll theranostic agent. Theranostics. 1: 354-62. PMID 21938263 DOI: 10.7150/Thno/V01P0354 |
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Lovell JF, Huynh E, Macdonald TD, Lin Q, Zheng G. Biodegradable star polymers shine for cancer drug delivery. Nanomedicine (London, England). 6: 1155. PMID 21929456 DOI: 10.2217/Nnm.11.116 |
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Lovell JF, Roxin A, Ng KK, Qi Q, McMullen JD, DaCosta RS, Zheng G. Porphyrin-cross-linked hydrogel for fluorescence-guided monitoring and surgical resection. Biomacromolecules. 12: 3115-8. PMID 21777008 DOI: 10.1021/Bm200784S |
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Yang M, Chen J, Cao W, Ding L, Ng KK, Jin H, Zhang Z, Zheng G. Attenuation of nontargeted cell-kill using a high-density lipoprotein-mimicking peptide--phospholipid nanoscaffold. Nanomedicine (London, England). 6: 631-41. PMID 21718175 DOI: 10.2217/Nnm.11.10 |
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Ng KK, Lovell JF, Zheng G. Lipoprotein-inspired nanoparticles for cancer theranostics. Accounts of Chemical Research. 44: 1105-13. PMID 21557543 DOI: 10.1021/Ar200017E |
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Marotta DE, Cao W, Wileyto EP, Li H, Corbin I, Rickter E, Glickson JD, Chance B, Zheng G, Busch TM. Evaluation of bacteriochlorophyll-reconstituted low-density lipoprotein nanoparticles for photodynamic therapy efficacy in vivo. Nanomedicine (London, England). 6: 475-87. PMID 21542686 DOI: 10.2217/Nnm.11.8 |
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Lovell JF, Jin CS, Huynh E, Jin H, Kim C, Rubinstein JL, Chan WC, Cao W, Wang LV, Zheng G. Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents. Nature Materials. 10: 324-32. PMID 21423187 DOI: 10.1038/Nmat2986 |
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Yang M, Jin H, Chen J, Ding L, Ng KK, Lin Q, Lovell JF, Zhang Z, Zheng G. Efficient cytosolic delivery of siRNA using HDL-mimicking nanoparticles. Small (Weinheim An Der Bergstrasse, Germany). 7: 568-73. PMID 21370456 DOI: 10.1002/Smll.201001589 |
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Jin H, Lovell JF, Chen J, Ng K, Cao W, Ding L, Zhang Z, Zheng G. Cytosolic delivery of LDL nanoparticle cargo using photochemical internalization. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 10: 810-6. PMID 21344108 DOI: 10.1039/C0Pp00350F |
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Moriyama E, Cao W, Liu T, Wang H, Zheng G, Wilson B. Novel optical probes for image-guided tumor resection and photodynamic therapy based on glucose transporters Photodiagnosis and Photodynamic Therapy. 8: 156. DOI: 10.1016/J.Pdpdt.2011.03.112 |
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Jin H, Lovell JF, Chen J, Ng K, Cao W, Ding L, Zhang Z, Zheng G. Investigating the specific uptake of EGF-conjugated nanoparticles in lung cancer cells using fluorescence imaging. Cancer Nanotechnology. 1: 71-78. PMID 26316895 DOI: 10.1007/S12645-010-0009-X |
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Tam NC, Scott BM, Voicu D, Wilson BC, Zheng G. Facile synthesis of Raman active phospholipid gold nanoparticles. Bioconjugate Chemistry. 21: 2178-82. PMID 21090645 DOI: 10.1021/Bc100386A |
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Popov AV, Mawn TM, Kim S, Zheng G, Delikatny EJ. Design and synthesis of phospholipase C and A2-activatable near-infrared fluorescent smart probes. Bioconjugate Chemistry. 21: 1724-7. PMID 20882956 DOI: 10.1021/Bc100271V |
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Lovell JF, Jin H, Ng KK, Zheng G. Programmed nanoparticle aggregation using molecular beacons. Angewandte Chemie (International Ed. in English). 49: 7917-9. PMID 20853381 DOI: 10.1002/Anie.201003846 |
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Hill ML, Corbin IR, Levitin RB, Cao W, Mainprize JG, Yaffe MJ, Zheng G. In vitro assessment of poly-iodinated triglyceride reconstituted low-density lipoprotein: initial steps toward CT molecular imaging. Academic Radiology. 17: 1359-65. PMID 20719547 DOI: 10.1016/J.Acra.2010.06.006 |
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Lovell JF, Chen J, Huynh E, Jarvi MT, Wilson BC, Zheng G. Facile synthesis of advanced photodynamic molecular beacon architectures. Bioconjugate Chemistry. 21: 1023-5. PMID 20509598 DOI: 10.1021/Bc100178Z |
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Liu TW, Chen J, Zheng G. Peptide-based molecular beacons for cancer imaging and therapy. Amino Acids. 41: 1123-34. PMID 20169374 DOI: 10.1007/S00726-010-0499-1 |
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Lovell JF, Liu TW, Chen J, Zheng G. Activatable photosensitizers for imaging and therapy. Chemical Reviews. 110: 2839-57. PMID 20104890 DOI: 10.1021/Cr900236H |
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Zhang Z, Chen J, Ding L, Jin H, Lovell JF, Corbin IR, Cao W, Lo PC, Yang M, Tsao MS, Luo Q, Zheng G. HDL-mimicking peptide-lipid nanoparticles with improved tumor targeting. Small (Weinheim An Der Bergstrasse, Germany). 6: 430-7. PMID 19957284 DOI: 10.1002/Smll.200901515 |
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Zhang Z, Cao W, Jin H, Lovell JF, Yang M, Ding L, Chen J, Corbin I, Luo Q, Zheng G. Biomimetic nanocarrier for direct cytosolic drug delivery. Angewandte Chemie (International Ed. in English). 48: 9171-5. PMID 19876988 DOI: 10.1002/Anie.200903112 |
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Cao W, Ng KK, Corbin I, Zhang Z, Ding L, Chen J, Zheng G. Synthesis and evaluation of a stable bacteriochlorophyll-analog and its incorporation into high-density lipoprotein nanoparticles for tumor imaging. Bioconjugate Chemistry. 20: 2023-31. PMID 19839633 DOI: 10.1021/Bc900404Y |
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Chen J, Liu TW, Lo PC, Wilson BC, Zheng G. "Zipper" molecular beacons: a generalized strategy to optimize the performance of activatable protease probes. Bioconjugate Chemistry. 20: 1836-42. PMID 19754039 DOI: 10.1021/Bc900207K |
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Lovell JF, Chen J, Jarvi MT, Cao WG, Allen AD, Liu Y, Tidwell TT, Wilson BC, Zheng G. FRET quenching of photosensitizer singlet oxygen generation. The Journal of Physical Chemistry. B. 113: 3203-11. PMID 19708269 DOI: 10.1021/Jp810324V |
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Lo PC, Chen J, Stefflova K, Warren MS, Navab R, Bandarchi B, Mullins S, Tsao M, Cheng JD, Zheng G. Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers. Journal of Medicinal Chemistry. 52: 358-68. PMID 19093877 DOI: 10.1021/Jm801052F |
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Chen J, Lovell JF, Lo PC, Stefflova K, Niedre M, Wilson BC, Zheng G. A tumor mRNA-triggered photodynamic molecular beacon based on oligonucleotide hairpin control of singlet oxygen production. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 7: 775-81. PMID 18597024 DOI: 10.1039/B800653A |
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Moriyama EH, Zheng G, Wilson BC. Optical molecular imaging: from single cell to patient. Clinical Pharmacology and Therapeutics. 84: 267-71. PMID 18388867 DOI: 10.1038/Clpt.2008.58 |
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Lovell JF, Zheng G. Activatable smart probes for molecular optical imaging and therapy Journal of Innovative Optical Health Sciences. 1: 45-61. DOI: 10.1142/S1793545808000157 |
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Chen J, Jarvi M, Lo PC, Stefflova K, Wilson BC, Zheng G. Using the singlet oxygen scavenging property of carotenoid in photodynamic molecular beacons to minimize photodamage to non-targeted cells. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 6: 1311-7. PMID 18046487 DOI: 10.1039/B706820D |
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Corbin IR, Zheng G. Mimicking nature's nanocarrier: synthetic low-density lipoprotein-like nanoparticles for cancer-drug delivery. Nanomedicine (London, England). 2: 375-80. PMID 17716181 DOI: 10.2217/17435889.2.3.375 |
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Stefflova K, Chen J, Zheng G. Killer beacons for combined cancer imaging and therapy. Current Medicinal Chemistry. 14: 2110-25. PMID 17691951 DOI: 10.2174/092986707781389655 |
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Zheng G, Chen J, Stefflova K, Jarvi M, Li H, Wilson BC. Photodynamic molecular beacon as an activatable photosensitizer based on protease-controlled singlet oxygen quenching and activation. Proceedings of the National Academy of Sciences of the United States of America. 104: 8989-94. PMID 17502620 DOI: 10.1073/Pnas.0611142104 |
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Stefflova K, Chen J, Zheng G. Using molecular beacons for cancer imaging and treatment. Frontiers in Bioscience : a Journal and Virtual Library. 12: 4709-21. PMID 17485407 DOI: 10.2741/2420 |
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Chen J, Corbin IR, Li H, Cao W, Glickson JD, Zheng G. Ligand conjugated low-density lipoprotein nanoparticles for enhanced optical cancer imaging in vivo. Journal of the American Chemical Society. 129: 5798-9. PMID 17428054 DOI: 10.1021/Ja069336K |
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Stefflova K, Li H, Chen J, Zheng G. Peptide-based pharmacomodulation of a cancer-targeted optical imaging and photodynamic therapy agent. Bioconjugate Chemistry. 18: 379-88. PMID 17298029 DOI: 10.1021/Bc0602578 |
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Corbin IR, Chen J, Li H, Cao W, Zheng G. Functionalizing low-density lipoprotein nanoparticles for In Vivo near-infrared optical imaging of cancer Molecular Imaging. 6626. DOI: 10.1117/12.728427 |
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Chen J, Lo PC, Warren M, Stefflova K, Cheng JD, Wilson BC, Zheng G. New linker design for biomarker-triggered photodynamic molecular beacons Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6626. DOI: 10.1117/12.728395 |
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Chen J, Stefflova K, Warren M, Bu J, Wilson BC, Zheng G. Rational design of a receptor-targeted photodynamic molecular beacon for the multi-level control of singlet oxygen production and PDT activity in cancer cells Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6449. DOI: 10.1117/12.699754 |
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Stefflova K, Chen J, Li H, Zheng G. Targeted photodynamic therapy agent with a built-in apoptosis sensor for in vivo near-infrared imaging of tumor apoptosis triggered by its photosensitization in situ. Molecular Imaging. 5: 520-32. PMID 17150164 DOI: 10.2310/7290.2006.00027 |
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Corbin IR, Li H, Chen J, Lund-Katz S, Zhou R, Glickson JD, Zheng G. Low-density lipoprotein nanoparticles as magnetic resonance imaging contrast agents. Neoplasia (New York, N.Y.). 8: 488-98. PMID 16820095 DOI: 10.1593/Neo.05835 |
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Stefflova K, Chen J, Marotta D, Li H, Zheng G. Photodynamic therapy agent with a built-in apoptosis sensor for evaluating its own therapeutic outcome in situ. Journal of Medicinal Chemistry. 49: 3850-6. PMID 16789741 DOI: 10.1021/Jm060146U |
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Zheng G, Chen J, Li H, Glickson JD. Rerouting lipoprotein nanoparticles to selected alternate receptors for the targeted delivery of cancer diagnostic and therapeutic agents. Proceedings of the National Academy of Sciences of the United States of America. 102: 17757-62. PMID 16306263 DOI: 10.1073/Pnas.0508677102 |
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Li H, Marotta DE, Kim S, Busch TM, Wileyto EP, Zheng G. High payload delivery of optical imaging and photodynamic therapy agents to tumors using phthalocyanine-reconstituted low-density lipoprotein nanoparticles. Journal of Biomedical Optics. 10: 41203. PMID 16178627 DOI: 10.1117/1.2011429 |
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| 2005 |
Wu SP, Lee I, Ghoroghchian PP, Frail PR, Zheng G, Glickson JD, Therien MJ. Near-infrared optical imaging of B16 melanoma cells via low-density lipoprotein-mediated uptake and delivery of high emission dipole strength tris[(porphinato)zinc(II)] fluorophores. Bioconjugate Chemistry. 16: 542-50. PMID 15898720 DOI: 10.1021/Bc0497416 |
0.361 |
|
| 2004 |
Zhang Z, Li H, Liu Q, Zhou L, Zhang M, Luo Q, Glickson J, Chance B, Zheng G. Metabolic imaging of tumors using intrinsic and extrinsic fluorescent markers. Biosensors & Bioelectronics. 20: 643-50. PMID 15494250 DOI: 10.1016/J.Bios.2004.03.034 |
0.472 |
|
| 2004 |
Chen J, Stefflova K, Niedre MJ, Wilson BC, Chance B, Glickson JD, Zheng G. Protease-triggered photosensitizing beacon based on singlet oxygen quenching and activation. Journal of the American Chemical Society. 126: 11450-1. PMID 15366886 DOI: 10.1021/Ja047392K |
0.405 |
|
| 2004 |
Zhang Z, Blessington D, Li H, Busch TM, Glickson J, Luo Q, Chance B, Zheng G. Redox ratio of mitochondria as an indicator for the response of photodynamic therapy. Journal of Biomedical Optics. 9: 772-8. PMID 15250765 DOI: 10.1117/1.1760759 |
0.445 |
|
| 2004 |
Li H, Zhang Z, Blessington D, Nelson DS, Zhou R, Lund-Katz S, Chance B, Glickson JD, Zheng G. Carbocyanine labeled LDL for optical imaging of tumors. Academic Radiology. 11: 669-77. PMID 15172369 DOI: 10.1016/J.Acra.2004.01.016 |
0.457 |
|
| 2004 |
Zhou L, Li X, Zhong B, Zhang D, Blessington D, Li H, Zheng G, Glickson J, Chance B. Developing 3D high-resolution imaging of pancreatic islet β cells in genetically obese-diabetic (ob/ob) mice Biosilico. DOI: 10.1364/Bio.2004.Thc5 |
0.395 |
|
| 2004 |
Zheng G, Chen Y, Intes X, Chance B, Glickson JD. Contrast-enhanced near-infrared (NIR) optical imaging for subsurface cancer detection Journal of Porphyrins and Phthalocyanines. 8: 1106-1117. DOI: 10.1142/S1088424604000477 |
0.617 |
|
| 2004 |
Li H, Chen J, Zhang M, Zhang Z, Benaron D, Chance B, Glickson J, Zheng G. NIR optical probes targeting glucose transporters Proceedings of Spie - the International Society For Optical Engineering. 5329: 254-261. DOI: 10.1117/12.533148 |
0.498 |
|
| 2003 |
Chen Y, Zheng G, Zhang ZH, Blessington D, Zhang M, Li H, Liu Q, Zhou L, Intes X, Achilefu S, Chance B. Metabolism-enhanced tumor localization by fluorescence imaging: in vivo animal studies. Optics Letters. 28: 2070-2. PMID 14587818 DOI: 10.1364/Ol.28.002070 |
0.643 |
|
| 2003 |
Zhang M, Zhang Z, Blessington D, Li H, Busch TM, Madrak V, Miles J, Chance B, Glickson JD, Zheng G. Pyropheophorbide 2-deoxyglucosamide: a new photosensitizer targeting glucose transporters. Bioconjugate Chemistry. 14: 709-14. PMID 12862422 DOI: 10.1021/Bc034038N |
0.488 |
|
| 2003 |
Zhang Z, Liu Q, Luo Q, Zhang M, Blessington D, Zhou L, Chodosh LA, Zheng G, Chance B. 3D imaging of the metabolic state of c-MYC-induced mammary tumor with the cryo-imager Proceedings of Spie - the International Society For Optical Engineering. 4955: 647-655. DOI: 10.1117/12.503163 |
0.44 |
|
| 2003 |
Blessington DM, Zhang Z, Li H, Zhang M, Zhou L, Glickson J, Zheng G, Chance B. Detection and imaging of the reconstituted pyropheophorbide-cholesterol oleate labeled low-density lipoprotein in the HepG2 tumor Proceedings of Spie - the International Society For Optical Engineering. 4955: 497-504. DOI: 10.1117/12.478190 |
0.467 |
|
| 2003 |
Chen Y, Blessington D, Zhang Z, Liu Q, Zhou L, Mu C, Intes X, Achilefu S, Li H, Zhang M, Zheng G, Chance B. Determination of subsurface tumor localization in animal models with near-infrared (NIR) fluorescence imaging Proceedings of Spie - the International Society For Optical Engineering. 4955: 322-329. DOI: 10.1117/12.478187 |
0.626 |
|
| 2003 |
Pandey SK, Gryshuk AL, Graham A, Ohkubo K, Fukuzumi S, Dobhal MP, Zheng G, Ou Z, Zhan R, Kadish KM, Oseroff A, Ramaprasad S, Pandey RK. Fluorinated photosensitizers: synthesis, photophysical, electrochemical, intracellular localization, in vitro photosensitizing efficacy and determination of tumor-uptake by 19F in vivo NMR spectroscopy Tetrahedron. 59: 10059-10073. DOI: 10.1016/J.Tet.2003.10.016 |
0.303 |
|
| 2002 |
Zheng G, Li H, Yang K, Blessington D, Licha K, Lund-Katz S, Chance B, Glickson JD. Tricarbocyanine cholesteryl laurates labeled LDL: new near infrared fluorescent probes (NIRFs) for monitoring tumors and gene therapy of familial hypercholesterolemia. Bioorganic & Medicinal Chemistry Letters. 12: 1485-8. PMID 12031325 DOI: 10.1016/S0960-894X(02)00193-2 |
0.467 |
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| 2002 |
Zheng G, Li H, Zhang M, Lund-Katz S, Chance B, Glickson JD. Low-density lipoprotein reconstituted by pyropheophorbide cholesteryl oleate as target-specific photosensitizer. Bioconjugate Chemistry. 13: 392-6. PMID 12009925 DOI: 10.1021/Bc025516H |
0.44 |
|
| 2001 |
Zheng G, Potter WR, Camacho SH, Missert JR, Wang G, Bellnier DA, Henderson BW, Rodgers MA, Dougherty TJ, Pandey RK. Synthesis, photophysical properties, tumor uptake, and preliminary in vivo photosensitizing efficacy of a homologous series of 3-(1'-alkyloxy)ethyl-3-devinylpurpurin-18-N-alkylimides with variable lipophilicity. Journal of Medicinal Chemistry. 44: 1540-59. PMID 11334564 DOI: 10.1021/Jm0005510 |
0.31 |
|
| 1999 |
Zheng G, Dougherty TJ, Pandey RK. Novel chlorin–diene building block by enyne metathesis: synthesis of chlorin–fullerene dyads Chemical Communications. 2469-2470. DOI: 10.1039/A906889I |
0.304 |
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| 1997 |
Pandey RK, Constantine S, Tsuchida T, Zheng G, Medforth CJ, Aoudia M, Kozyrev AN, Rodgers MA, Kato H, Smith KM, Dougherty TJ. Synthesis, photophysical properties, in vivo photosensitizing efficacy, and human serum albumin binding properties of some novel bacteriochlorins. Journal of Medicinal Chemistry. 40: 2770-9. PMID 9276023 DOI: 10.1021/Jm9702894 |
0.301 |
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| 1997 |
Kozyrev AN, Zheng G, Lazarou E, Dougherty TJ, Smith KM, Pandey RK. Syntheses of emeraldin and purpurin-18 analogs as target-specific photosensitizers for photodynamic therapy Tetrahedron Letters. 38: 3335-3338. DOI: 10.1016/S0040-4039(97)00621-7 |
0.307 |
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| 1996 |
Kozyrev AN, Zheng G, Zhu C, Dougherty TJ, Smith KM, Pandey RK. Syntheses of stable bacteriochlorophyll-a derivatives as potential photosensitizers for photodynamic therapy Tetrahedron Letters. 37: 6431-6434. DOI: 10.1016/0040-4039(96)01346-9 |
0.318 |
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