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David I. Rabuka, Ph.D. - Publications

Affiliations: 
2008 University of California, Berkeley, Berkeley, CA, United States 
Area:
Bioorthogonal chemistry
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44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sharrar A, Arake de Tacca L, Meacham Z, Staples-Ager J, Collingwood T, Rabuka D, Schelle M. Discovery and engineering of AiEvo2, a novel Cas12a nuclease for human gene editing applications. The Journal of Biological Chemistry. 105685. PMID 38272227 DOI: 10.1016/j.jbc.2024.105685  0.717
2023 Meacham Z, de Tacca LA, Bondy-Denomy J, Rabuka D, Schelle M. Cas9 degradation in human cells using phage anti-CRISPR proteins. Plos Biology. 21: e3002431. PMID 38064533 DOI: 10.1371/journal.pbio.3002431  0.73
2023 Sharrar A, Arake de Tacca L, Collingwood T, Meacham Z, Rabuka D, Staples-Ager J, Schelle M. Discovery and Characterization of Novel Type V Cas12f Nucleases with Diverse Protospacer Adjacent Motif Preferences. The Crispr Journal. PMID 37267210 DOI: 10.1089/crispr.2023.0006  0.699
2020 Rupniewski I, Rabuka D. Site-Specific Labeling of Proteins Using the Formylglycine-Generating Enzyme (FGE). Methods in Molecular Biology (Clifton, N.J.). 2012: 63-81. PMID 31161504 DOI: 10.1007/978-1-4939-9546-2_5  0.329
2019 Harel ET, Drake PM, Barfield RM, Lui I, Farr-Jones S, Van't Veer L, Gartner ZJ, Green EM, Lourenço AL, Cheng Y, Hann BC, Rabuka D, Craik CS. Antibody-Drug Conjugates Targeting the Urokinase Receptor (uPAR) as a Possible Treatment of Aggressive Breast Cancer. Antibodies (Basel, Switzerland). 8. PMID 31694242 DOI: 10.3390/Antib8040054  0.619
2019 Walker JA, Sorkin MR, Ledesma F, Kabaria SR, Barfield RM, Rabuka D, Alabi CA. Hydrophilic sequence-defined crosslinkers for antibody-drug conjugates. Bioconjugate Chemistry. PMID 31671265 DOI: 10.1021/Acs.Bioconjchem.9B00713  0.351
2019 Tsui CK, Barfield RM, Fischer CR, Morgens DW, Li A, Smith BAH, Gray MA, Bertozzi CR, Rabuka D, Bassik MC. CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity. Nature Chemical Biology. PMID 31451760 DOI: 10.1038/S41589-019-0342-2  0.491
2019 Hernandez-Alba O, Houel S, Hessmann S, Erb S, Rabuka D, Huguet R, Josephs J, Beck A, Drake PM, Cianférani S. A Case Study to Identify the Drug Conjugation Site of a Site-Specific Antibody-Drug-Conjugate Using Middle-Down Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 31429052 DOI: 10.1007/S13361-019-02296-2  0.318
2019 Liu J, Barfield RM, Rabuka D. Site-Specific Bioconjugation Using SMARTag Technology: A Practical and Effective Chemoenzymatic Approach to Generate Antibody-Drug Conjugates. Methods in Molecular Biology (Clifton, N.J.). 2033: 131-147. PMID 31332752 DOI: 10.1007/978-1-4939-9654-4_10  0.326
2019 Bauzon M, Drake PM, Barfield RM, Cornali BM, Rupniewski I, Rabuka D. Maytansine-bearing antibody-drug conjugates induce in vitro hallmarks of immunogenic cell death selectively in antigen-positive target cells Oncoimmunology. 8. PMID 30906660 DOI: 10.1080/2162402X.2019.1565859  0.356
2018 Linz T, Yeo D, Hong Q, Zmolek W, McFarland J, Barfield RM, Haskins WE, Rabuka D. Systematic LC/MS/MS Investigations for the IND-Enabling Extended Characterization of Antibody-Drug Conjugate Modifications. Antibodies (Basel, Switzerland). 7. PMID 31544890 DOI: 10.3390/Antib7040040  0.335
2018 Huang BCB, Kim YC, Bañas S, Barfield RM, Drake PM, Rupniewski I, Haskins WE, Rabuka D. Antibody-drug conjugate library prepared by scanning insertion of the aldehyde tag into IgG1 constant regions. Mabs. 1-8. PMID 30252630 DOI: 10.1080/19420862.2018.1512327  0.414
2018 Barfield RM, Rabuka D. Leveraging Formylglycine-Generating Enzyme for Production of Site-Specifically Modified Bioconjugates. Methods in Molecular Biology (Clifton, N.J.). 1728: 3-16. PMID 29404988 DOI: 10.1007/978-1-4939-7574-7_1  0.325
2018 Harel E, McFarland J, Bleck G, Brain S, Drake P, Rabuka D, Vantveer L, Craik C. Abstract P3-05-22: Anti-uPAR antibody drug conjugates for targeted therapy of triple-negative breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P3-05-22  0.335
2017 Drake PM, Rabuka D. Recent Developments in ADC Technology: Preclinical Studies Signal Future Clinical Trends. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. PMID 29119409 DOI: 10.1007/S40259-017-0254-1  0.308
2017 Walder R, LeBlanc MA, Van Patten WJ, Edwards D, Greenberg JA, Adhikari A, Okoniewski SR, Sullan RMA, Rabuka D, Sousa MC, Perkins TT. Rapid Characterization of a Mechanically Labile α-helical Protein Enabled by Efficient Site-Specific Bioconjugation. Journal of the American Chemical Society. PMID 28677396 DOI: 10.1021/Jacs.7B02958  0.395
2017 Botzanowski T, Erb S, Hernandez-Alba O, Ehkirch A, Colas O, Wagner-Rousset E, Rabuka D, Beck A, Drake PM, Cianférani S. Insights from native mass spectrometry approaches for top- and middle- level characterization of site-specific antibody-drug conjugates. Mabs. 9: 801-811. PMID 28406343 DOI: 10.1080/19420862.2017.1316914  0.32
2017 LeBlanc M, Edwards DT, Walder R, Rabuka D, Perkins TT, Sousa MC. Heterobifunctional Polyprotein for Efficient Characterization of Mechanically Labile Proteins Biophysical Journal. 112: 455a-456a. DOI: 10.1016/J.Bpj.2016.11.2441  0.383
2016 Kudirka RA, Barfield RM, McFarland JM, Drake PM, Carlson A, Bañas S, Zmolek W, Garofalo AW, Rabuka D. Site-Specific Tandem Knoevenagel Condensation-Michael Addition To Generate Antibody-Drug Conjugates. Acs Medicinal Chemistry Letters. 7: 994-998. PMID 27882197 DOI: 10.1021/Acsmedchemlett.6B00253  0.402
2016 Zmolek W, Bañas S, Barfield RM, Rabuka D, Drake PM. A simple LC/MRM-MS-based method to quantify free linker-payload in antibody-drug conjugate preparations. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. PMID 27311685 DOI: 10.1016/J.Jchromb.2016.05.055  0.331
2016 York D, Baker J, Holder PG, Jones LC, Drake PM, Barfield RM, Bleck GT, Rabuka D. Generating aldehyde-tagged antibodies with high titers and high formylglycine yields by supplementing culture media with copper(II). Bmc Biotechnology. 16: 23. PMID 26911368 DOI: 10.1186/S12896-016-0254-0  0.343
2015 Liu J, Hanne J, Britton BM, Shoffner M, Albers AE, Bennett J, Zatezalo R, Barfield R, Rabuka D, Lee JB, Fishel R. An Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore. Scientific Reports. 5: 16883. PMID 26582263 DOI: 10.1038/Srep16883  0.422
2015 Kudirka R, Barfield RM, McFarland J, Albers AE, de Hart GW, Drake PM, Holder PG, Banas S, Jones LC, Garofalo AW, Rabuka D. Generating site-specifically modified proteins via a versatile and stable nucleophilic carbon ligation. Chemistry & Biology. 22: 293-8. PMID 25619935 DOI: 10.1016/J.Chembiol.2014.11.019  0.421
2014 Albers AE, Garofalo AW, Drake PM, Kudirka R, de Hart GW, Barfield RM, Baker J, Banas S, Rabuka D. Exploring the effects of linker composition on site-specifically modified antibody-drug conjugates. European Journal of Medicinal Chemistry. 88: 3-9. PMID 25176286 DOI: 10.1016/J.Ejmech.2014.08.062  0.386
2014 Liang SI, McFarland JM, Rabuka D, Gartner ZJ. A modular approach for assembling aldehyde-tagged proteins on DNA scaffolds. Journal of the American Chemical Society. 136: 10850-3. PMID 25029632 DOI: 10.1021/Ja504711N  0.663
2014 Drake PM, Albers AE, Baker J, Banas S, Barfield RM, Bhat AS, de Hart GW, Garofalo AW, Holder P, Jones LC, Kudirka R, McFarland J, Zmolek W, Rabuka D. Aldehyde tag coupled with HIPS chemistry enables the production of ADCs conjugated site-specifically to different antibody regions with distinct in vivo efficacy and PK outcomes. Bioconjugate Chemistry. 25: 1331-41. PMID 24924618 DOI: 10.1021/Bc500189Z  0.374
2013 Agarwal P, Kudirka R, Albers AE, Barfield RM, de Hart GW, Drake PM, Jones LC, Rabuka D. Hydrazino-Pictet-Spengler ligation as a biocompatible method for the generation of stable protein conjugates. Bioconjugate Chemistry. 24: 846-51. PMID 23731037 DOI: 10.1021/Bc400042A  0.349
2013 Agarwal P, van der Weijden J, Sletten EM, Rabuka D, Bertozzi CR. A Pictet-Spengler ligation for protein chemical modification. Proceedings of the National Academy of Sciences of the United States of America. 110: 46-51. PMID 23237853 DOI: 10.1073/pnas.1213186110  0.674
2012 Rabuka D, Rush JS, deHart GW, Wu P, Bertozzi CR. Site-specific chemical protein conjugation using genetically encoded aldehyde tags. Nature Protocols. 7: 1052-67. PMID 22576105 DOI: 10.1038/Nprot.2012.045  0.727
2012 Hudak JE, Barfield RM, de Hart GW, Grob P, Nogales E, Bertozzi CR, Rabuka D. Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag. Angewandte Chemie (International Ed. in English). 51: 4161-5. PMID 22407566 DOI: 10.1002/Anie.201108130  0.752
2011 Zhen C, McCabe IP, Rabuka D, Bader RA, Forstner MB. A biosynthetic Membrane-Anchor/Protein System Based on a Genetically Encoded “Aldehyde Tag” Biophysical Journal. 100: 332a. DOI: 10.1016/J.Bpj.2010.12.2014  0.416
2010 Rabuka D. Chemoenzymatic methods for site-specific protein modification. Current Opinion in Chemical Biology. 14: 790-6. PMID 21030291 DOI: 10.1016/j.cbpa.2010.09.020  0.349
2009 Godula K, Umbel ML, Rabuka D, Botyanszki Z, Bertozzi CR, Parthasarathy R. Control of the molecular orientation of membrane-anchored biomimetic glycopolymers. Journal of the American Chemical Society. 131: 10263-8. PMID 19580278 DOI: 10.1021/Ja903114G  0.683
2009 Godula K, Rabuka D, Nam KT, Bertozzi CR. Synthesis and microcontact printing of dual end-functionalized mucin-like glycopolymers for microarray applications. Angewandte Chemie (International Ed. in English). 48: 4973-6. PMID 19479916 DOI: 10.1002/Anie.200805756  0.674
2009 Harland CW, Botyanszki Z, Rabuka D, Bertozzi CR, Parthasarathy R. Synthetic trehalose glycolipids confer desiccation resistance to supported lipid monolayers. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 5193-8. PMID 19323499 DOI: 10.1021/La804007A  0.482
2009 Wu P, Shui W, Carlson BL, Hu N, Rabuka D, Lee J, Bertozzi CR. Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag. Proceedings of the National Academy of Sciences of the United States of America. 106: 3000-5. PMID 19202059 DOI: 10.1073/Pnas.0807820106  0.764
2009 Harland C, Botyanszki Z, Rabuka D, Bertozzi C, Parthasarathy R. Synthetic and Mycobacterial Trehalose Glycolipids Confer Dehydration Resistance to Supported Phospholipid Monolayers Biophysical Journal. 96: 164a. DOI: 10.1016/J.Bpj.2008.12.753  0.482
2008 Rabuka D, Forstner MB, Groves JT, Bertozzi CR. Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes. Journal of the American Chemical Society. 130: 5947-53. PMID 18402449 DOI: 10.1021/Ja710644G  0.531
2008 Harland CW, Rabuka D, Bertozzi CR, Parthasarathy R. The Mycobacterium tuberculosis virulence factor trehalose dimycolate imparts desiccation resistance to model mycobacterial membranes. Biophysical Journal. 94: 4718-24. PMID 18326657 DOI: 10.1529/Biophysj.107.125542  0.461
2007 Parthasarathy R, Rabuka D, Bertozzi CR, Groves JT. Molecular orientation of membrane-anchored mucin glycoprotein mimics. The Journal of Physical Chemistry. B. 111: 12133-5. PMID 17915910 DOI: 10.1021/Jp072136Q  0.515
2007 Rabuka D, Parthasarathy R, Lee GS, Chen X, Groves JT, Bertozzi CR. Hierarchical assembly of model cell surfaces: synthesis of mucin mimetic polymers and their display on supported bilayers. Journal of the American Chemical Society. 129: 5462-71. PMID 17425309 DOI: 10.1021/Ja067819I  0.582
2006 Rabuka D, Hubbard SC, Laughlin ST, Argade SP, Bertozzi CR. A chemical reporter strategy to probe glycoprotein fucosylation. Journal of the American Chemical Society. 128: 12078-9. PMID 16967952 DOI: 10.1021/Ja064619Y  0.712
2006 Chen X, Tam UC, Czlapinski JL, Lee GS, Rabuka D, Zettl A, Bertozzi CR. Interfacing carbon nanotubes with living cells. Journal of the American Chemical Society. 128: 6292-3. PMID 16683774 DOI: 10.1021/Ja060276S  0.521
2002 Bryan MC, Plettenburg O, Sears P, Rabuka D, Wacowich-Sgarbi S, Wong CH. Saccharide display on microtiter plates. Chemistry & Biology. 9: 713-20. PMID 12079783 DOI: 10.1016/S1074-5521(02)00155-2  0.311
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