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Matthew S. Tremblay, Ph.D. - Publications

Affiliations: 
California Institute for Biomedical Research 
 2007 Columbia University, New York, NY 
Area:
Drug discovery
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Marrocco V, Tran T, Zhu S, Choi SH, Gamo AM, Li S, Fu Q, Cunado MD, Roland J, Hull M, Nguyen-Tran V, Joseph S, Chatterjee AK, Rogers N, Tremblay MS, et al. A small molecule UPR modulator for diabetes identified by high throughput screening. Acta Pharmaceutica Sinica. B. 11: 3983-3993. PMID 35024320 DOI: 10.1016/j.apsb.2021.05.018  0.495
2020 Lear S, Pflimlin E, Zhou Z, Huang D, Weng S, Nguyen-Tran V, Joseph SB, Roller S, Peterson S, Li J, Tremblay M, Schultz PG, Shen W. Engineering of a Potent, Long-Acting NPY2R Agonist for Combination with a GLP-1R Agonist as a Multi-Hormonal Treatment for Obesity. Journal of Medicinal Chemistry. PMID 32844654 DOI: 10.1021/Acs.Jmedchem.0C00740  0.605
2020 Johnson K, Woods A, Joseph S, Chatterjee A, Zhu S, Wisler J, Klyushnichenko V, Li J, Lotz M, Tremblay M, Schultz P. Development of KA34 as a cartilage regenerative therapy for Osteoarthritis Osteoarthritis and Cartilage. 28: S518. DOI: 10.1016/J.Joca.2020.02.814  0.612
2019 Ardestani A, Tremblay MS, Shen W, Maedler K. Neratinib is an MST1 inhibitor and restores pancreatic β-cells in diabetes. Cell Death Discovery. 5: 149. PMID 31815004 DOI: 10.1038/S41420-019-0232-0  0.53
2019 Ardestani A, Li S, Annamalai K, Lupse B, Geravandi S, Dobrowolski A, Yu S, Zhu S, Baguley TD, Surakattula M, Oetjen J, Hauberg-Lotte L, Herranz R, Awal S, Altenhofen D, ... ... Tremblay MS, et al. Neratinib protects pancreatic beta cells in diabetes. Nature Communications. 10: 5015. PMID 31676778 DOI: 10.1038/S41467-019-12880-5  0.641
2019 Pflimlin E, Lear S, Lee C, Yu S, Zou H, To A, Joseph S, Nguyen-Tran V, Tremblay MS, Shen W. Design of a Long-Acting and Selective MEG-Fatty Acid Stapled Prolactin-Releasing Peptide Analog. Acs Medicinal Chemistry Letters. 10: 1166-1172. PMID 31413801 DOI: 10.1021/Acsmedchemlett.9B00182  0.513
2018 Janes J, Young ME, Chen E, Rogers NH, Burgstaller-Muehlbacher S, Hughes LD, Love MS, Hull MV, Kuhen KL, Woods AK, Joseph SB, Petrassi HM, McNamara CW, Tremblay MS, Su AI, et al. The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America. 115: 10750-10755. PMID 30282735 DOI: 10.1073/Pnas.1810137115  0.746
2018 Miglianico M, Eldering M, Slater H, Ferguson N, Ambrose P, Lees RS, Koolen KMJ, Pruzinova K, Jancarova M, Volf P, Koenraadt CJM, Duerr HP, Trevitt G, Yang B, Chatterjee AK, ... ... Tremblay MS, et al. Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases. Proceedings of the National Academy of Sciences of the United States of America. PMID 29967151 DOI: 10.1073/Pnas.1801338115  0.45
2018 Zhong L, Tran T, Baguley TD, Lee SJ, Henke A, To A, Li S, Yu S, Grieco FA, Roland J, Schultz PG, Eizirik DL, Rogers N, Chartterjee AK, Tremblay MS, et al. A Novel Inhibitor of iNOS Dimerization Protects Against Cytokine-Induced Rat β-cell Dysfunction. British Journal of Pharmacology. PMID 29888783 DOI: 10.1111/Bph.14388  0.618
2018 Muse ED, Yu S, Edillor CR, Tao J, Spann NJ, Troutman TD, Seidman JS, Henke A, Roland JT, Ozeki KA, Thompson BM, McDonald JG, Bahadorani J, Tsimikas S, Grossman TR, ... Tremblay MS, et al. Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages. Proceedings of the National Academy of Sciences of the United States of America. PMID 29632203 DOI: 10.1073/Pnas.1714518115  0.366
2017 Yu S, Chen E, Sherwood L, Hull M, Woods AK, Tremblay MS. Ex Vivo Cell-Based Screening Platform for Modulators of Hepatosteatosis. Acs Chemical Biology. PMID 28586195 DOI: 10.1021/Acschembio.7B00420  0.352
2017 Yu S, Pearson A, Lim R, Rodgers D, Li S, Parker H, Weglarz M, Hampton E, Bollong M, Shen J, Zumbaldo C, Wang D, Woods A, Wright T, Schultz P, ... ... Tremblay M, et al. P-262 A PDE4 Inhibitor-antibody Conjugate for Treating Ulcerative Colitis Inflammatory Bowel Diseases. 23. DOI: 10.1097/01.Mib.0000512805.98510.C0  0.718
2016 Shaaban KA, Saunders MA, Zhang Y, Tran T, Elshahawi SI, Ponomareva LV, Wang X, Zhang J, Copley GC, Sunkara M, Kharel MK, Morris AJ, Hower JC, Tremblay MS, Prendergast MA, et al. Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6. Journal of Natural Products. PMID 28029795 DOI: 10.1021/Acs.Jnatprod.6B00948  0.452
2016 Yu S, Pearson AD, Lim RK, Rodgers DT, Li S, Parker HB, Weglarz M, Hampton EN, Bollong MJ, Shen J, Zambaldo C, Wang D, Woods AK, Wright TM, Schultz PG, ... ... Tremblay MS, et al. Targeted delivery of an anti-inflammatory PDE4 inhibitor to immune cells via an antibody-drug conjugate. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27731313 DOI: 10.1038/Mt.2016.175  0.73
2016 Yu S, Li S, Henke A, Muse ED, Cheng B, Welzel G, Chatterjee AK, Wang D, Roland J, Glass CK, Tremblay M. Dissociated sterol-based liver X receptor agonists as therapeutics for chronic inflammatory diseases. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 30: 2570-9. PMID 27025962 DOI: 10.1096/Fj.201600244R  0.327
2015 Lim RK, Yu S, Cheng B, Li S, Kim NJ, Cao Y, Chi V, Kim JY, Chatterjee AK, Schultz PG, Tremblay MS, Kazane SA. Targeted Delivery of LXR Agonist Using a Site-Specific Antibody-Drug Conjugate. Bioconjugate Chemistry. 26: 2216-22. PMID 25945727 DOI: 10.1021/Acs.Bioconjchem.5B00203  0.779
2015 Wang RE, Liu T, Wang Y, Cao Y, Du J, Luo X, Deshmukh V, Kim CH, Lawson BR, Tremblay MS, Young TS, Kazane SA, Wang F, Schultz PG. An immunosuppressive antibody-drug conjugate. Journal of the American Chemical Society. 137: 3229-32. PMID 25699419 DOI: 10.1021/Jacs.5B00620  0.752
2013 Swoboda JG, Elliott J, Deshmukh V, de Lichtervelde L, Shen W, Tremblay MS, Peters EC, Cho CY, Lu B, Girman S, Wang S, Schultz PG. Small molecule mediated proliferation of primary retinal pigment epithelial cells. Acs Chemical Biology. 8: 1407-11. PMID 23621521 DOI: 10.1021/Cb4001712  0.72
2013 Shen W, Tremblay MS, Deshmukh VA, Wang W, Filippi CM, Harb G, Zhang YQ, Kamireddy A, Baaten JE, Jin Q, Wu T, Swoboda JG, Cho CY, Li J, Laffitte BA, et al. Small-molecule inducer of β cell proliferation identified by high-throughput screening. Journal of the American Chemical Society. 135: 1669-72. PMID 23330637 DOI: 10.1021/Ja309304M  0.761
2013 Shen W, Tremblay MS, Deshmukh VA, Wang W, Filippi CM, Harb G, Zhang Y, Kamireddy A, Baaten JE, Jin Q, Wu T, Swoboda JG, Peters EC, Cho CY, Li J, et al. Correction to “Small-Molecule Inducer of β Cell Proliferation Identified by High-Throughput Screening” Journal of the American Chemical Society. 135: 4573-4573. DOI: 10.1021/Ja401118G  0.738
2012 Johnson K, Zhu S, Tremblay MS, Payette JN, Wang J, Bouchez LC, Meeusen S, Althage A, Cho CY, Wu X, Schultz PG. A stem cell-based approach to cartilage repair. Science (New York, N.Y.). 336: 717-21. PMID 22491093 DOI: 10.1126/Science.1215157  0.701
2011 Lee M, Tremblay MS, Jockusch S, Turro NJ, Sames D. Intermolecular energy transfer from Tb3+ to Eu3+ in aqueous aggregates and on the surface of human cells. Organic Letters. 13: 2802-5. PMID 21563789 DOI: 10.1021/Ol200328P  0.621
2009 Wang W, Walker JR, Wang X, Tremblay MS, Lee JW, Wu X, Schultz PG. Identification of small-molecule inducers of pancreatic beta-cell expansion. Proceedings of the National Academy of Sciences of the United States of America. 106: 1427-32. PMID 19164755 DOI: 10.1073/Pnas.0811848106  0.743
2009 Wang W, Walker JR, Wang X, Tremblay MS, Lee JW, Wu X, Schultz PG. Erratum: Identification of small-molecule inducers of pancreatic β-cell expansion (Proceedings of the National Academy of Sciences of the United States of America (2009) 106 (1427-1432)) Proceedings of the National Academy of Sciences of the United States of America. 106. DOI: 10.1073/Pnas.0901524106  0.622
2008 Tremblay MS, Lee M, Sames D. A luminescent sensor for tyrosine phosphorylation. Organic Letters. 10: 5-8. PMID 18069839 DOI: 10.1021/Ol701920X  0.618
2007 Halim M, Tremblay MS, Jockusch S, Turro NJ, Sames D. Transposing molecular fluorescent switches into the near-IR: development of luminogenic reporter substrates for redox metabolism. Journal of the American Chemical Society. 129: 7704-5. PMID 17542585 DOI: 10.1021/Ja071311D  0.54
2007 Tremblay MS, Halim M, Sames D. Cocktails of Tb(3+) and Eu(3+) complexes: a general platform for the design of ratiometric optical probes. Journal of the American Chemical Society. 129: 7570-7. PMID 17518468 DOI: 10.1021/Ja070867Y  0.538
2006 Tremblay MS, Sames D. Synthesis of luminescent heterometallic bis-lanthanide complexes via selective, sequential metallation. Chemical Communications (Cambridge, England). 4116-8. PMID 17024267 DOI: 10.1039/B607949K  0.537
2006 Tremblay MS, Zhu Q, Martí AA, Dyer J, Halim M, Jockusch S, Turro NJ, Sames D. Phosphorylation state-responsive lanthanide peptide conjugates: a luminescence switch based on reversible complex reorganization. Organic Letters. 8: 2723-6. PMID 16774241 DOI: 10.1021/Ol060614U  0.546
2005 Tremblay MS, Sames D. A new fluorogenic transformation: development of an optical probe for coenzyme Q. Organic Letters. 7: 2417-20. PMID 15932212 DOI: 10.1021/Ol0507569  0.537
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