Year |
Citation |
Score |
2012 |
Cleland JL, Geething NC, Moore JA, Rogers BC, Spink BJ, Wang CW, Alters SE, Stemmer WP, Schellenberger V. A novel long-acting human growth hormone fusion protein (VRS-317): enhanced in vivo potency and half-life. Journal of Pharmaceutical Sciences. 101: 2744-54. PMID 22678811 DOI: 10.1002/jps.23229 |
0.664 |
|
2010 |
Geething NC, To W, Spink BJ, Scholle MD, Wang CW, Yin Y, Yao Y, Schellenberger V, Cleland JL, Stemmer WP, Silverman J. Gcg-XTEN: an improved glucagon capable of preventing hypoglycemia without increasing baseline blood glucose. Plos One. 5: e10175. PMID 20418955 DOI: 10.1371/journal.pone.0010175 |
0.618 |
|
2010 |
Cleland J, Geething N, Spink B, Lee L, Motlagh S, Yao Y, Silverman J. OR2,9 A novel human growth hormone XTEN construct (VRS-317) for once-a-month subcutaneous administration Growth Hormone & Igf Research. 20: S5. DOI: 10.1016/S1096-6374(10)70015-0 |
0.644 |
|
2009 |
Schellenberger V, Wang CW, Geething NC, Spink BJ, Campbell A, To W, Scholle MD, Yin Y, Yao Y, Bogin O, Cleland JL, Silverman J, Stemmer WP. A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner. Nature Biotechnology. 27: 1186-90. PMID 19915550 DOI: 10.1038/nbt.1588 |
0.654 |
|
2008 |
Sivaramakrishnan S, Spink BJ, Sim AY, Doniach S, Spudich JA. Dynamic charge interactions create surprising rigidity in the ER/K alpha-helical protein motif. Proceedings of the National Academy of Sciences of the United States of America. 105: 13356-61. PMID 18768817 DOI: 10.1073/Pnas.0806256105 |
0.569 |
|
2008 |
Spink BJ, Sivaramakrishnan S, Lipfert J, Doniach S, Spudich JA. Long single alpha-helical tail domains bridge the gap between structure and function of myosin VI. Nature Structural & Molecular Biology. 15: 591-7. PMID 18511944 DOI: 10.1038/Nsmb.1429 |
0.576 |
|
2005 |
Rock RS, Ramamurthy B, Dunn AR, Beccafico S, Rami BR, Morris C, Spink BJ, Franzini-Armstrong C, Spudich JA, Sweeney HL. A flexible domain is essential for the large step size and processivity of myosin VI. Molecular Cell. 17: 603-9. PMID 15721263 DOI: 10.1016/J.Molcel.2005.01.015 |
0.614 |
|
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