☰

Wei-Chieh Cheng, Ph.D. - Publications

Affiliations: 
Academia Sinica, Moni Vatopediou, Taipei City, Taiwan 
Area:
Combinatorial chemistry, heterocyclic chemistry, understanding reaction mechanisms, solid phase organic synthesis, polymer chemistry, organic synthesis, reaction methodology, and structure elucidation
Tree Info Similar researchers PubMed Report error

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Chen WA, Li HY, Sayyad A, Huang CY, Cheng WC. Synthesis of Nitrone-derived Pyrrolidine Scaffolds and Their Combinatorial Libraries to Develop Selective α-L-Rhamnosidase Inhibitors. Chemistry, An Asian Journal. PMID 35535638 DOI: 10.1002/asia.202200172  0.688
2020 Cheng WC, You TY, Teo ZZ, Sayyad AA, Maharana J, Guo CW, Liang PH, Lin CS, Meng FC. Further insights on structural modifications of muramyl dipeptides to study the human NOD2 stimulating activity. Chemistry, An Asian Journal. PMID 32975372 DOI: 10.1002/asia.202001003  0.687
2020 Cheng WC, Liu WJ, Hu KH, Tan YL, Lin YT, Chen WA, Lo LC. Rapid Synthesis of a Natural Product-Inspired Uridine Containing Library. Acs Combinatorial Science. PMID 32833425 DOI: 10.1021/acscombsci.0c00011  0.311
2018 Cheng WC, Lin CK, Li HY, Chang YC, Lu SJ, Chen YS, Chang SY. A combinatorial approach towards the synthesis of non-hydrolysable triazole-iduronic acid hybrid inhibitors of human α-l-iduronidase: discovery of enzyme stabilizers for the potential treatment of MPSI. Chemical Communications (Cambridge, England). PMID 29473068 DOI: 10.1039/C7Cc09642A  0.407
2018 Wu WS, Cheng WC, Cheng TR, Wong CH. Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase. Journal of the American Chemical Society. PMID 29411975 DOI: 10.1021/Jacs.7B13205  0.303
2016 Lin CK, Hou CC, Guo YY, Cheng WC. Design and Synthesis of Orthogonally Protected d- and l-β-Hydroxyenduracididines from d-lyxono-1,4-Lactone. Organic Letters. PMID 27690463 DOI: 10.1021/Acs.Orglett.6B02444  0.375
2016 Chen KT, Chen PT, Lin CK, Huang LY, Hu CM, Chang YF, Hsu HT, Cheng TR, Wu YT, Cheng WC. Structural Investigation of Park's Nucleotide on Bacterial Translocase MraY: Discovery of Unexpected MraY Inhibitors. Scientific Reports. 6: 31579. PMID 27531195 DOI: 10.1038/Srep31579  0.367
2016 Cheng WC, Wang JH, Li HY, Lu SJ, Hu JM, Yun WY, Chiu CH, Yang WB, Chien YH, Hwu WL. Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new pharmacological chaperone for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency. European Journal of Medicinal Chemistry. 123: 14-20. PMID 27474919 DOI: 10.1016/J.Ejmech.2016.07.025  0.314
2016 Lin CK, Yun WY, Lin LT, Cheng WC. A concise approach to the synthesis of the unique N-mannosyl d-β-hydroxyenduracididine moiety in the mannopeptimycin series of natural products. Organic & Biomolecular Chemistry. PMID 27055669 DOI: 10.1039/C6Ob00644B  0.388
2015 Chen KT, Huang DY, Chiu CH, Lin WW, Liang PH, Cheng WC. Synthesis of Diverse N-Substituted Muramyl Dipeptide Derivatives and Their Use in a Study of Human NOD2 Stimulation Activity. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 11984-8. PMID 26226896 DOI: 10.1002/Chem.201501557  0.362
2015 Lin CK, Chen KT, Hu CM, Yun WY, Cheng WC. Synthesis of 1-C-Glycoside-Linked Lipid II Analogues Toward Bacterial Transglycosylase Inhibition. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 7511-9. PMID 25820317 DOI: 10.1002/Chem.201406629  0.381
2015 Lin CK, Cheng LW, Li HY, Yun WY, Cheng WC. Synthesis of novel polyhydroxylated pyrrolidine-triazole/-isoxazole hybrid molecules. Organic & Biomolecular Chemistry. 13: 2100-7. PMID 25525831 DOI: 10.1039/C4Ob01934B  0.421
2015 Chen PT, Lin CK, Tsai CJ, Huang DY, Nien FY, Lin WW, Cheng WC. Expeditious synthesis of enantiopure, orthogonally protected bis-α-amino acids (OPBAAs) and their use in a study of Nod1 stimulation. Chemistry, An Asian Journal. 10: 474-82. PMID 25504924 DOI: 10.1002/Asia.201403173  0.446
2015 Cheng WC, Guo CW, Lin CK, Jiang YR. Synthesis and inhibition study of bicyclic iminosugar-based alkaloids, scaffolds, and libraries towards glucosidase Israel Journal of Chemistry. 55: 403-411. DOI: 10.1002/Ijch.201400140  0.45
2014 Hsu CH, Schelwies M, Enck S, Huang LY, Huang SH, Chang YF, Cheng TJ, Cheng WC, Wong CH. Iminosugar C-glycoside analogues of α-D-GlcNAc-1-phosphate: synthesis and bacterial transglycosylase inhibition. The Journal of Organic Chemistry. 79: 8629-37. PMID 25137529 DOI: 10.1021/Jo501340S  0.42
2014 Huang LY, Huang SH, Chang YC, Cheng WC, Cheng TJ, Wong CH. Enzymatic synthesis of lipid II and analogues. Angewandte Chemie (International Ed. in English). 53: 8060-5. PMID 24990652 DOI: 10.1002/Anie.201402313  0.341
2013 Huang SH, Wu WS, Huang LY, Huang WF, Fu WC, Chen PT, Fang JM, Cheng WC, Cheng TJ, Wong CH. New continuous fluorometric assay for bacterial transglycosylase using Förster resonance energy transfer. Journal of the American Chemical Society. 135: 17078-89. PMID 24131464 DOI: 10.1021/Ja407985M  0.34
2013 Cheng TJ, Chan TH, Tsou EL, Chang SY, Yun WY, Yang PJ, Wu YT, Cheng WC. From natural product-inspired pyrrolidine scaffolds to the development of new human Golgi α-mannosidase II inhibitors. Chemistry, An Asian Journal. 8: 2600-4. PMID 23943613 DOI: 10.1002/Asia.201300680  0.338
2013 Pan YW, Guo CW, Tu HY, Tsai CW, Cheng WC. Solid-phase synthesis of diverse spiroisoxazolinodiketopiperazines. Acs Combinatorial Science. 15: 425-34. PMID 23889462 DOI: 10.1021/Co4000248  0.417
2012 Shih HW, Chen KT, Cheng WC. One-pot synthesis of phosphate diesters and phosphonate monoesters via a combination of microwave-CCl 3CN-pyridine coupling conditions Tetrahedron Letters. 53: 243-246. DOI: 10.1016/J.Tetlet.2011.11.032  0.341
2011 Meng FC, Chen KT, Huang LY, Shih HW, Chang HH, Nien FY, Liang PH, Cheng TJ, Wong CH, Cheng WC. Total synthesis of polyprenyl N-glycolyl lipid II as a mycobacterial transglycosylase substrate. Organic Letters. 13: 5306-9. PMID 21913698 DOI: 10.1021/Ol2021687  0.39
2011 Chang YF, Guo CW, Chan TH, Pan YW, Tsou EL, Cheng WC. Parallel synthesis of natural product-like polyhydroxylated pyrrolidine and piperidine alkaloids. Molecular Diversity. 15: 203-14. PMID 20563842 DOI: 10.1007/S11030-010-9255-4  0.391
2010 Cheng TJ, Wu YT, Yang ST, Lo KH, Chen SK, Chen YH, Huang WI, Yuan CH, Guo CW, Huang LY, Chen KT, Shih HW, Cheng YS, Cheng WC, Wong CH. High-throughput identification of antibacterials against methicillin-resistant Staphylococcus aureus (MRSA) and the transglycosylase. Bioorganic & Medicinal Chemistry. 18: 8512-29. PMID 21075637 DOI: 10.1016/J.Bmc.2010.10.036  0.314
2010 Shih HW, Chen KT, Chen SK, Huang CY, Cheng TJ, Ma C, Wong CH, Cheng WC. Combinatorial approach toward synthesis of small molecule libraries as bacterial transglycosylase inhibitors. Organic & Biomolecular Chemistry. 8: 2586-93. PMID 20485795 DOI: 10.1039/C000622J  0.381
2010 Liu CY, Guo CW, Chang YF, Wang JT, Shih HW, Hsu YF, Chen CW, Chen SK, Wang YC, Cheng TJ, Ma C, Wong CH, Fang JM, Cheng WC. Synthesis and evaluation of a new fluorescent transglycosylase substrate: lipid II-based molecule possessing a dansyl-C20 polyprenyl moiety. Organic Letters. 12: 1608-11. PMID 20187630 DOI: 10.1021/Ol100338V  0.321
2010 Chan TH, Chang YF, Hsu JJ, Cheng WC. Straightforward synthesis of diverse 1-deoxyazapyranosides via stereocontrolled nucleophilic additions to six-membered cyclic nitrones European Journal of Organic Chemistry. 5555-5559. DOI: 10.1002/Ejoc.201001045  0.376
2009 Shih HW, Guo CW, Lo KH, Huang MY, Cheng WC. Solution-phase parallel synthesis of novel spirooxazolinoisoxazolines. Journal of Combinatorial Chemistry. 11: 281-7. PMID 19199644 DOI: 10.1021/Cc800158T  0.371
2009 Tsou EL, Yeh YT, Liang PH, Cheng WC. A convenient approach toward the synthesis of enantiopure isomers of DMDP and ADMDP Tetrahedron. 65: 93-100. DOI: 10.1016/J.Tet.2008.10.096  0.416
2008 Tsou EL, Chen SY, Yang MH, Wang SC, Cheng TR, Cheng WC. Synthesis and biological evaluation of a 2-aryl polyhydroxylated pyrrolidine alkaloid-based library. Bioorganic & Medicinal Chemistry. 16: 10198-204. PMID 19008111 DOI: 10.1016/J.Bmc.2008.10.063  0.408
2008 Chang YF, Liu CY, Guo CW, Wang YC, Fang JM, Cheng WC. Solid-phase organic synthesis of polyisoprenoid alcohols with traceless sulfone linker. The Journal of Organic Chemistry. 73: 7197-203. PMID 18707172 DOI: 10.1021/Jo8010182  0.351
2008 Shih HW, Cheng WC. Solution-phase parallel synthesis of highly diverse spiroisoxazolinohydantoins Tetrahedron Letters. 49: 1008-1011. DOI: 10.1016/J.Tetlet.2007.12.008  0.384
2008 Chang YF, Jiang YR, Cheng WC. Traceless sulfone linker cleavage triggered by ozonolysis: solid-phase synthesis of diverse α-β-unsaturated carbonyl compounds Tetrahedron Letters. 49: 543-547. DOI: 10.1016/J.Tetlet.2007.11.064  0.416
2002 Cheng WC, Liu Y, Wong M, Olmstead MM, Lam KS, Kurth MJ. Stereoselective synthesis of unnatural spiroisoxazolinoproline-based amino acids and derivatives. The Journal of Organic Chemistry. 67: 5673-7. PMID 12153267 DOI: 10.1021/Jo025611J  0.646
2002 Cheng WC, Kurth MJ. The sulfone linker in solid-phase synthesis: preparation of 3,5-disubstituted cyclopent-2-enones. The Journal of Organic Chemistry. 67: 4387-91. PMID 12076132 DOI: 10.1021/Jo0256843  0.476
2002 Cheng WC, Wong M, Olmstead MM, Kurth MJ. Solid-phase synthesis of novel isoxazolocyclobutanones and isoxazolinocyclobutenones. Organic Letters. 4: 741-4. PMID 11869116 DOI: 10.1021/Ol017194N  0.477
2002 Cheng WC, Kurth MJ. The zincke reaction. A review Organic Preparations and Procedures International. 34: 585-608. DOI: 10.1080/00304940209355784  0.343
2002 Cheng WC, Lin CC, Kurth MJ. Dimsyl anion in the monoalkylation of solid-phase alkyl sulfones Tetrahedron Letters. 43: 2967-2970. DOI: 10.1016/S0040-4039(02)00423-9  0.483
2001 Cheng WC, Olmstead MM, Kurth MJ. Vinyl sulfones in solid-phase synthesis: preparation of 4,5,6,7-tetrahydroisoindole derivatives. The Journal of Organic Chemistry. 66: 5528-33. PMID 11485478 DOI: 10.1021/Jo0156823  0.526
1999 Cheng WC, Halm C, Evarts JB, Olmstead MM, Kurth MJ. Allylic sulfones in solid-phase synthesis: Preparation of cyclobutylidenes Journal of Organic Chemistry. 64: 8557-8562. DOI: 10.1021/Jo990954B  0.5
Show low-probability matches.