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Daniel W. Kulp, Ph.D. - Publications

Affiliations: 
2010 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Organic Chemistry, Chemical Biology, De Novo Protein Design
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Moyer TJ, Kato Y, Abraham W, Chang JYH, Kulp DW, Watson N, Turner HL, Menis S, Abbott RK, Bhiman JN, Melo MB, Simon HA, Herrera-De la Mata S, Liang S, Seumois G, et al. Engineered immunogen binding to alum adjuvant enhances humoral immunity. Nature Medicine. PMID 32066977 DOI: 10.1038/S41591-020-0753-3  0.301
2019 Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, et al. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science (New York, N.Y.). PMID 31672916 DOI: 10.1126/Science.Aax4380  0.3
2018 Tokatlian T, Read BJ, Jones CA, Kulp DW, Menis S, Chang JYH, Steichen JM, Kumari S, Allen JD, Dane EL, Liguori A, Sangesland M, Lingwood D, Crispin M, Schief WR, et al. Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers. Science (New York, N.Y.). PMID 30573546 DOI: 10.1126/Science.Aat9120  0.302
2017 Kulp DW, Steichen JM, Pauthner M, Hu X, Schiffner T, Liguori A, Cottrell CA, Havenar-Daughton C, Ozorowski G, Georgeson E, Kalyuzhniy O, Willis JR, Kubitz M, Adachi Y, Reiss SM, et al. Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding. Nature Communications. 8: 1655. PMID 29162799 DOI: 10.1038/S41467-017-01549-6  0.321
2017 Cao L, Diedrich JK, Kulp DW, Pauthner M, He L, Park SR, Sok D, Su CY, Delahunty CM, Menis S, Andrabi R, Guenaga J, Georgeson E, Kubitz M, Adachi Y, et al. Global site-specific N-glycosylation analysis of HIV envelope glycoprotein. Nature Communications. 8: 14954. PMID 28348411 DOI: 10.1038/Ncomms14954  0.328
2017 Crooks ET, Osawa K, Tong T, Grimley SL, Dai YD, Whalen RG, Kulp DW, Menis S, Schief WR, Binley JM. Effects of partially dismantling the CD4 binding site glycan fence of HIV-1 Envelope glycoprotein trimers on neutralizing antibody induction. Virology. 505: 193-209. PMID 28279830 DOI: 10.1016/J.Virol.2017.02.024  0.303
2016 Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O, Briney B, Schiffner T, Garces F, Freund NT, Gitlin AD, et al. HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies. Immunity. PMID 27617678 DOI: 10.1016/J.Immuni.2016.08.016  0.331
2016 Briney B, Sok D, Jardine JG, Kulp DW, Skog P, Menis S, Jacak R, Kalyuzhniy O, de Val N, Sesterhenn F, Le KM, Ramos A, Jones M, Saye-Francisco KL, Blane TR, et al. Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies. Cell. 166: 1459-1470.e11. PMID 27610570 DOI: 10.1016/J.Cell.2016.08.005  0.309
2015 Pritchard LK, Spencer DI, Royle L, Bonomelli C, Seabright GE, Behrens AJ, Kulp DW, Menis S, Krumm SA, Dunlop DC, Crispin DJ, Bowden TA, Scanlan CN, Ward AB, Schief WR, et al. Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies. Nature Communications. 6: 7479. PMID 26105115 DOI: 10.1038/Ncomms8479  0.318
2015 Jardine JG, Ota T, Sok D, Pauthner M, Kulp DW, Kalyuzhniy O, Skog PD, Thinnes TC, Bhullar D, Briney B, Menis S, Jones M, Kubitz M, Spencer S, Adachi Y, et al. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen. Science (New York, N.Y.). PMID 26089355 DOI: 10.1126/Science.Aac5894  0.331
2015 Crooks ET, Tong T, Chakrabarti B, Narayan K, Georgiev IS, Menis S, Huang X, Kulp D, Osawa K, Muranaka J, Stewart-Jones G, Destefano J, O'Dell S, LaBranche C, Robinson JE, et al. Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site. Plos Pathogens. 11: e1004932. PMID 26023780 DOI: 10.1371/Journal.Ppat.1004932  0.33
2015 Zhang SQ, Kulp DW, Schramm CA, Mravic M, Samish I, DeGrado WF. The membrane- and soluble-protein helix-helix interactome: similar geometry via different interactions. Structure (London, England : 1993). 23: 527-41. PMID 25703378 DOI: 10.1016/J.Str.2015.01.009  0.737
2014 Bates JT, Keefer CJ, Slaughter JC, Kulp DW, Schief WR, Crowe JE. Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein. Virology. 454: 139-44. PMID 24725940 DOI: 10.1016/J.Virol.2014.02.010  0.311
2013 Smith BC, Underbakke ES, Kulp DW, Schief WR, Marletta MA. Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation. Proceedings of the National Academy of Sciences of the United States of America. 110: E3577-86. PMID 24003111 DOI: 10.1073/Pnas.1313331110  0.34
2013 Kulp DW, Schief WR. Advances in structure-based vaccine design. Current Opinion in Virology. 3: 322-31. PMID 23806515 DOI: 10.1016/J.Coviro.2013.05.010  0.347
2012 Reig AJ, Pires MM, Snyder RA, Wu Y, Jo H, Kulp DW, Butch SE, Calhoun JR, Szyperski T, Szyperski TG, Solomon EI, DeGrado WF. Alteration of the oxygen-dependent reactivity of de novo Due Ferri proteins. Nature Chemistry. 4: 900-6. PMID 23089864 DOI: 10.1038/Nchem.1454  0.731
2012 Kulp DW, Subramaniam S, Donald JE, Hannigan BT, Mueller BK, Grigoryan G, Senes A. Structural informatics, modeling, and design with an open-source Molecular Software Library (MSL). Journal of Computational Chemistry. 33: 1645-61. PMID 22565567 DOI: 10.1002/Jcc.22968  0.664
2012 Reig AJ, Pires MM, Snyder RA, Wu Y, Jo H, Kulp DW, Butch SE, Calhoun JR, Szyperski T, Solomon EI, DeGrado WF. Erratum: Alteration of the oxygen-dependent reactivity of de novo Due Ferri proteins Nature Chemistry. 4: 1050-1050. DOI: 10.1038/Nchem.1519  0.706
2011 Gront D, Kulp DW, Vernon RM, Strauss CE, Baker D. Generalized fragment picking in Rosetta: design, protocols and applications. Plos One. 6: e23294. PMID 21887241 DOI: 10.1371/Journal.Pone.0023294  0.329
2011 Korendovych IV, Kulp DW, Wu Y, Cheng H, Roder H, DeGrado WF. Design of a switchable eliminase. Proceedings of the National Academy of Sciences of the United States of America. 108: 6823-7. PMID 21482808 DOI: 10.1073/Pnas.1018191108  0.683
2011 Donald JE, Kulp DW, DeGrado WF. Salt bridges: geometrically specific, designable interactions. Proteins. 79: 898-915. PMID 21287621 DOI: 10.1002/Prot.22927  0.545
2011 Korendovych I, Kulp D, Wu Y, Cheng H, Roder H, DeGrado W. Calmodulin, C-terminal domain, F92E mutant Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Kz2/Pdb  0.626
2010 Berger BW, Kulp DW, Span LM, DeGrado JL, Billings PC, Senes A, Bennett JS, DeGrado WF. Consensus motif for integrin transmembrane helix association. Proceedings of the National Academy of Sciences of the United States of America. 107: 703-8. PMID 20080739 DOI: 10.1073/Pnas.0910873107  0.733
2009 Zhang Y, Kulp DW, Lear JD, DeGrado WF. Experimental and computational evaluation of forces directing the association of transmembrane helices. Journal of the American Chemical Society. 131: 11341-3. PMID 19722646 DOI: 10.1021/Ja904625B  0.511
2009 Metcalf DG, Kulp DW, Bennett JS, DeGrado WF. Multiple approaches converge on the structure of the integrin alphaIIb/beta3 transmembrane heterodimer. Journal of Molecular Biology. 392: 1087-101. PMID 19527732 DOI: 10.1016/J.Jmb.2009.06.032  0.73
2009 Miller MW, Basra S, Kulp DW, Billings PC, Choi S, Beavers MP, McCarty OJ, Zou Z, Kahn ML, Bennett JS, DeGrado WF. Small-molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism. Proceedings of the National Academy of Sciences of the United States of America. 106: 719-24. PMID 19141632 DOI: 10.1073/Pnas.0811622106  0.607
2008 Berger BW, Span LM, Kulp DW, Billings PC, DeGrado WF, Bennett JS. A Conserved Transmembrane Domain Interface Regulates Integrin Function Blood. 112: 2858-2858. DOI: 10.1182/Blood.V112.11.2858.2858  0.646
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