Year |
Citation |
Score |
2012 |
Xu N, Libertini S, Black EJ, Lao Y, Hegarat N, Walker M, Gillespie DA. Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage. Oncogene. 31: 1086-94. PMID 21765472 DOI: 10.1038/Onc.2011.310 |
0.334 |
|
2009 |
Li L, Perdigao J, Pegg AE, Lao Y, Hecht SS, Lindgren BR, Reardon JT, Sancar A, Wattenberg EV, Peterson LA. The influence of repair pathways on the cytotoxicity and mutagenicity induced by the pyridyloxobutylation pathway of tobacco-specific nitrosamines. Chemical Research in Toxicology. 22: 1464-72. PMID 19601657 DOI: 10.1021/Tx9001572 |
0.596 |
|
2009 |
Zhang S, Wang M, Villalta PW, Lindgren BR, Lao Y, Hecht SS. Quantitation of pyridyloxobutyl DNA adducts in nasal and oral mucosa of rats treated chronically with enantiomers of N'-nitrosonornicotine. Chemical Research in Toxicology. 22: 949-56. PMID 19405515 DOI: 10.1021/Tx900040J |
0.68 |
|
2009 |
Zhang S, Wang M, Villalta PW, Lindgren BR, Upadhyaya P, Lao Y, Hecht SS. Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Chemical Research in Toxicology. 22: 926-36. PMID 19358518 DOI: 10.1021/Tx900015D |
0.674 |
|
2007 |
Wang M, Lao Y, Cheng G, Shi Y, Villalta PW, Nishikawa A, Hecht SS. Analysis of adducts in hepatic DNA of rats treated with N-nitrosopyrrolidine. Chemical Research in Toxicology. 20: 634-40. PMID 17394361 DOI: 10.1021/Tx600333E |
0.623 |
|
2007 |
Wang M, Lao Y, Cheng G, Shi Y, Villalta PW, Hecht SS. Identification of adducts formed in the reaction of alpha-acetoxy-N-nitrosopyrrolidine with deoxyribonucleosides and DNA. Chemical Research in Toxicology. 20: 625-33. PMID 17394360 DOI: 10.1021/Tx600332P |
0.638 |
|
2007 |
Lao Y, Yu N, Kassie F, Villalta PW, Hecht SS. Analysis of pyridyloxobutyl DNA adducts in F344 rats chronically treated with (R)- and (S)-N'-nitrosonornicotine. Chemical Research in Toxicology. 20: 246-56. PMID 17305408 DOI: 10.1021/Tx060208J |
0.637 |
|
2007 |
Lao Y, Yu N, Kassie F, Villalta PW, Hecht SS. Formation and accumulation of pyridyloxobutyl DNA adducts in F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Chemical Research in Toxicology. 20: 235-45. PMID 17305407 DOI: 10.1021/Tx060207R |
0.572 |
|
2007 |
Hecht SS, Han S, Kenney PM, Wang M, Lindgren B, Wang Y, Lao Y, Hochalter JB, Upadhyaya P. Investigation of the reaction of myosmine with sodium nitrite in vitro and in rats. Chemical Research in Toxicology. 20: 543-9. PMID 17291014 DOI: 10.1021/Tx600328E |
0.58 |
|
2006 |
Liu X, Lao Y, Yang IY, Hecht SS, Moriya M. Replication-coupled repair of crotonaldehyde/acetaldehyde-induced guanine-guanine interstrand cross-links and their mutagenicity. Biochemistry. 45: 12898-905. PMID 17042508 DOI: 10.1021/Bi060792V |
0.542 |
|
2006 |
Stein S, Lao Y, Yang IY, Hecht SS, Moriya M. Genotoxicity of acetaldehyde- and crotonaldehyde-induced 1,N2-propanodeoxyguanosine DNA adducts in human cells. Mutation Research. 608: 1-7. PMID 16797223 DOI: 10.1016/J.Mrgentox.2006.01.009 |
0.565 |
|
2006 |
Lao Y, Villalta PW, Sturla SJ, Wang M, Hecht SS. Quantitation of pyridyloxobutyl DNA adducts of tobacco-specific nitrosamines in rat tissue DNA by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. Chemical Research in Toxicology. 19: 674-82. PMID 16696570 DOI: 10.1021/Tx050351X |
0.69 |
|
2005 |
Sturla SJ, Scott J, Lao Y, Hecht SS, Villalta PW. Mass spectrometric analysis of relative levels of pyridyloxobutylation adducts formed in the reaction of DNA with a chemically activated form of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Chemical Research in Toxicology. 18: 1048-55. PMID 15962940 DOI: 10.1021/Tx050028U |
0.687 |
|
2005 |
Lao Y, Hecht SS. Synthesis and properties of an acetaldehyde-derived oligonucleotide interstrand cross-link. Chemical Research in Toxicology. 18: 711-21. PMID 15833031 DOI: 10.1021/Tx0497292 |
0.521 |
|
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