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Hacer Karatas, Ph.D. - Publications

Affiliations: 
2012 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Nanoscale analytical techniques, chemical separations, mass spectrometry, microfluidics, neurochemistry, and islet biology
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Adihou H, Gopalakrishnan R, Förster T, Guéret SM, Gasper R, Geschwindner S, Carrillo García C, Karatas H, Pobbati AV, Vazquez-Chantada M, Davey P, Wassvik CM, Pang JKS, Soh BS, Hong W, et al. A protein tertiary structure mimetic modulator of the Hippo signalling pathway. Nature Communications. 11: 5425. PMID 33110077 DOI: 10.1038/s41467-020-19224-8  0.436
2020 Karatas H, Akbarzadeh M, Adihou H, Hahne G, Pobbati AV, Yihui Ng E, Guéret SM, Sievers S, Pahl A, Metz M, Zinken S, Dötsch L, Nowak C, Thavam S, Friese A, et al. Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain (TEAD) Central Pocket. Journal of Medicinal Chemistry. PMID 32907324 DOI: 10.1021/Acs.Jmedchem.0C01275  0.531
2019 Pobbati AV, Mejuch T, Chakraborty S, Karatas H, Bharath SR, Guéret SM, Goy PA, Hahne G, Pahl A, Sievers S, Guccione E, Song H, Waldmann H, Hong W. Identification of Quinolinols as Activators of TEAD-dependent Transcription. Acs Chemical Biology. PMID 31742995 DOI: 10.1021/Acschembio.9B00786  0.389
2017 Karatas H, Li Y, Liu L, Ji J, Lee S, Chen Y, Yang J, Huang L, Bernard D, Xu J, Townsend EC, Cao F, Ran X, Li X, Wen B, et al. Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction. Journal of Medicinal Chemistry. PMID 28603984 DOI: 10.1021/Acs.Jmedchem.6B01796  0.591
2016 Liu L, Lei I, Karatas H, Li Y, Wang L, Gnatovskiy L, Dou Y, Wang S, Qian L, Wang Z. Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts. Cell Discovery. 2: 16036. PMID 27924221 DOI: 10.1038/Celldisc.2016.36  0.483
2016 Xu J, Li L, Xiong J, denDekker A, Ye A, Karatas H, Liu L, Wang H, Qin ZS, Wang S, Dou Y. MLL1 and MLL1 fusion proteins have distinct functions in regulating leukemic transcription program. Cell Discovery. 2: 16008. PMID 27462455 DOI: 10.1038/Celldisc.2016.8  0.58
2016 Zhang H, Gayen S, Xiong J, Zhou B, Shanmugam AK, Sun Y, Karatas H, Liu L, Rao RC, Wang S, Nesvizhskii AI, Kalantry S, Dou Y. MLL1 Inhibition Reprograms Epiblast Stem Cells to Naive Pluripotency. Cell Stem Cell. PMID 26996599 DOI: 10.1016/J.Stem.2016.02.004  0.471
2015 Karatas H, Lee SY, Townsend EC, Cao F, Xu J, Bernard D, Liu L, Dou Y, Wang S. Structure-based design of conformationally constrained cyclic peptidomimetics to target the MLL1-WDR5 protein-protein interaction as inhibitors of the MLL1 methyltransferase activity Chinese Chemical Letters. 26: 455-458. DOI: 10.1016/J.Cclet.2015.03.030  0.624
2014 Cao F, Townsend EC, Karatas H, Xu J, Li L, Lee S, Liu L, Chen Y, Ouillette P, Zhu J, Hess JL, Atadja P, Lei M, Qin ZS, Malek S, et al. Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia. Molecular Cell. 53: 247-61. PMID 24389101 DOI: 10.1016/J.Molcel.2013.12.001  0.559
2013 Zhou H, Liu L, Huang J, Bernard D, Karatas H, Navarro A, Lei M, Wang S. Structure-based design of high-affinity macrocyclic peptidomimetics to block the menin-mixed lineage leukemia 1 (MLL1) protein-protein interaction. Journal of Medicinal Chemistry. 56: 1113-23. PMID 23244744 DOI: 10.1021/Jm3015298  0.621
2013 Karatas H, Townsend EC, Cao F, Chen Y, Bernard D, Liu L, Lei M, Dou Y, Wang S. High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction. Journal of the American Chemical Society. 135: 669-82. PMID 23210835 DOI: 10.1021/Ja306028Q  0.661
2012 Townsend EC, Cao F, Karatas H, Wang S, Dou Y. Abstract LB-256: Targeting MLL1 methyltransferase activity for treatment of acute leukemia with MLL1 rearrangement Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-256  0.59
2010 Karatas H, Townsend EC, Bernard D, Dou Y, Wang S. Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction. Journal of Medicinal Chemistry. 53: 5179-85. PMID 20575550 DOI: 10.1021/Jm100139B  0.615
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