W. Mark Saltzman - Publications

Affiliations: 
1987-1996 Chemical engineering Johns Hopkins University, Baltimore, MD 
 1996-2002 Chemical engineering Cornell University, Ithaca, NY, United States 
 2002- Biomedical Engineering Yale University, New Haven, CT 
Website:
https://medicine.yale.edu/profile/mark-saltzman/

202 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ricciardi AS, Barone C, Putman R, Quijano E, Gupta A, Nguyen R, Mandl H, Piotrowski-Daspit AS, Lopez-Giraldez F, Luks V, Freedman-Weiss MR, Farrelly J, Ahle S, Glazer PM, Saltzman WM, et al. Systemic in utero gene editing as a treatment for cystic fibrosis. Biorxiv : the Preprint Server For Biology. PMID 39282330 DOI: 10.1101/2024.09.04.611031  0.681
2024 Gupta A, Barone C, Quijano E, Piotrowski-Daspit AS, Perera JD, Riccardi A, Jamali H, Turchick A, Zao W, Saltzman WM, Glazer PM, Egan ME. Next generation triplex-forming PNAs for site-specific genome editing of the F508del CFTR mutation. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 39107154 DOI: 10.1016/j.jcf.2024.07.009  0.681
2024 Piotrowski-Daspit AS, Bracaglia LG, Eaton DA, Richfield O, Binns TC, Albert C, Gould J, Mortlock RD, Egan ME, Pober JS, Saltzman WM. Enhancing in vivo cell and tissue targeting by modulation of polymer nanoparticles and macrophage decoys. Nature Communications. 15: 4247. PMID 38762483 DOI: 10.1038/s41467-024-48442-7  0.642
2023 Oyaghire SN, Quijano E, Perera JDR, Mandl HK, Saltzman WM, Bahal R, Glazer PM. DNA recognition and induced genome modification by a hydroxymethyl-γ tail-clamp peptide nucleic acid. Cell Reports. Physical Science. 4. PMID 37920723 DOI: 10.1016/j.xcrp.2023.101635  0.509
2022 Putman R, Ricciardi AS, Carufe KEW, Quijano E, Bahal R, Glazer PM, Saltzman WM. Nanoparticle-mediated genome editing in single-cell embryos via peptide nucleic acids. Bioengineering & Translational Medicine. 8: e10458. PMID 37206203 DOI: 10.1002/btm2.10458  0.528
2022 Piotrowski-Daspit AS, Barone C, Lin CY, Deng Y, Wu D, Binns TC, Xu E, Ricciardi AS, Putman R, Garrison A, Nguyen R, Gupta A, Fan R, Glazer PM, Saltzman WM, et al. In vivo correction of cystic fibrosis mediated by PNA nanoparticles. Science Advances. 8: eabo0522. PMID 36197984 DOI: 10.1126/sciadv.abo0522  0.703
2022 Liu J, Wang X, Chen AT, Gao X, Himes BT, Zhang H, Chen Z, Wang J, Sheu WC, Deng G, Xiao Y, Zou P, Zhang S, Liu F, Zhu Y, ... ... Saltzman WM, et al. ZNF117 regulates glioblastoma stem cell differentiation towards oligodendroglial lineage. Nature Communications. 13: 2196. PMID 35459228 DOI: 10.1038/s41467-022-29884-3  0.551
2022 Luks VL, Mandl H, DiRito J, Barone C, Freedman-Weiss MR, Ricciardi AS, Tietjen GG, Egan ME, Saltzman WM, Stitelman DH. Surface conjugation of antibodies improves nanoparticle uptake in bronchial epithelial cells. Plos One. 17: e0266218. PMID 35385514 DOI: 10.1371/journal.pone.0266218  0.64
2021 Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, ... ... Saltzman WM, et al. The NIH Somatic Cell Genome Editing program. Nature. 592: 195-204. PMID 33828315 DOI: 10.1038/s41586-021-03191-1  0.63
2021 Ullrich SJ, Freedman-Weiss M, Ahle S, Mandl HK, Piotrowski-Daspit AS, Roberts K, Yung N, Maassel N, Bauer-Pisani T, Ricciardi AS, Egan ME, Glazer PM, Saltzman WM, Stitelman DH. Nanoparticles for Delivery of Agents to Fetal Lungs. Acta Biomaterialia. PMID 33484911 DOI: 10.1016/j.actbio.2021.01.024  0.69
2020 DiRito JR, Hosgood SA, Reschke M, Albert C, Bracaglia LG, Ferdinand JR, Stewart BJ, Edwards CM, Vaish AG, Thiru S, Mulligan DC, Haakinson DJ, Clatworthy MR, Saltzman WM, Pober JS, et al. Lysis of cold-storage-induced microvascular obstructions for ex vivo revitalization of marginal human kidneys. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 32627324 DOI: 10.1111/Ajt.16148  0.321
2020 Piotrowski-Daspit AS, Kauffman AC, Bracaglia LG, Saltzman WM. Polymeric vehicles for nucleic acid delivery. Advanced Drug Delivery Reviews. PMID 32585159 DOI: 10.1016/J.Addr.2020.06.014  0.382
2020 Oyaghire SN, Quijano E, Piotrowski-Daspit AS, Saltzman WM, Glazer PM. Poly(Lactic-co-Glycolic Acid) Nanoparticle Delivery of Peptide Nucleic Acids In Vivo. Methods in Molecular Biology (Clifton, N.J.). 2105: 261-281. PMID 32088877 DOI: 10.1007/978-1-0716-0243-0_17  0.625
2020 Economos NG, Oyaghire S, Quijano E, Ricciardi AS, Saltzman WM, Glazer PM. Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair. Molecules (Basel, Switzerland). 25. PMID 32046275 DOI: 10.3390/Molecules25030735  0.551
2020 Bracaglia LG, Piotrowski-Daspit AS, Lin CY, Moscato ZM, Wang Y, Tietjen GT, Saltzman WM. High-throughput quantitative microscopy-based half-life measurements of intravenously injected agents. Proceedings of the National Academy of Sciences of the United States of America. PMID 32015123 DOI: 10.1073/Pnas.1915450117  0.606
2020 Jiang Y, Lu Q, Wang Y, Xu E, Ho A, Singh P, Wang Y, Jiang Z, Yang F, Tietjen GT, Cresswell P, Saltzman WM. Quantitating Endosomal Escape of a Library of Polymers for mRNA Delivery. Nano Letters. PMID 32003222 DOI: 10.1021/Acs.Nanolett.9B04426  0.637
2019 Mandl HK, Quijano E, Suh HW, Sparago E, Oeck S, Grun M, Glazer PM, Saltzman WM. Optimizing biodegradable nanoparticle size for tissue-specific delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 314: 92-101. PMID 31654688 DOI: 10.1016/J.Jconrel.2019.09.020  0.586
2019 Merola J, Reschke M, Pierce RW, Qin L, Spindler S, Baltazar T, Manes TD, Lopez-Giraldez F, Li G, Bracaglia LG, Xie C, Kirkiles-Smith N, Saltzman WM, Tietjen GT, Tellides G, et al. Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression. Jci Insight. PMID 31527312 DOI: 10.1172/Jci.Insight.129739  0.31
2019 Cui J, Piotrowski-Daspit AS, Zhang J, Shao M, Bracaglia LG, Utsumi T, Seo YE, DiRito J, Song E, Wu C, Inada A, Tietjen GT, Pober JS, Iwakiri Y, Saltzman WM. Poly(amine-co-ester) nanoparticles for effective Nogo-B knockdown in the liver. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31054286 DOI: 10.1016/J.Jconrel.2019.04.044  0.351
2019 Seo YE, Suh HW, Bahal R, Josowitz A, Zhang J, Song E, Cui J, Noorbakhsh S, Jackson C, Bu T, Piotrowski-Daspit A, Bindra R, Saltzman WM. Nanoparticle-mediated intratumoral inhibition of miR-21 for improved survival in glioblastoma. Biomaterials. 201: 87-98. PMID 30802686 DOI: 10.1016/J.Biomaterials.2019.02.016  0.357
2018 Piotrowski-Daspit AS, Glazer PM, Saltzman WM. Debugging the genetic code: non-viral in vivo delivery of therapeutic genome editing technologies. Current Opinion in Biomedical Engineering. 7: 24-32. PMID 30984891 DOI: 10.1016/J.Cobme.2018.08.002  0.562
2018 Siefert AL, Cartiera MS, Khalid AN, Nantel MC, Loose CR, Schulam PG, Saltzman WM, Dempsey MK. The Yale Center for Biomedical Innovation and Technology (CBIT): One Model to Accelerate Impact From Academic Health Care Innovation. Academic Medicine : Journal of the Association of American Medical Colleges. PMID 30520807 DOI: 10.1097/Acm.0000000000002542  0.744
2018 Kauffman AC, Piotrowski-Daspit AS, Nakazawa KH, Jiang Y, Datye A, Saltzman WM. Tunability of Biodegradable Poly(amine-co-ester) Polymers for Customized Nucleic Acid Delivery and Other Biomedical Applications. Biomacromolecules. PMID 30110158 DOI: 10.1021/Acs.Biomac.8B00997  0.384
2018 Ricciardi AS, Bahal R, Farrelly JS, Quijano E, Bianchi AH, Luks VL, Putman R, López-Giráldez F, Coşkun S, Song E, Liu Y, Hsieh WC, Ly DH, Stitelman DH, Glazer PM, ... Saltzman WM, et al. In utero nanoparticle delivery for site-specific genome editing. Nature Communications. 9: 2481. PMID 29946143 DOI: 10.1038/S41467-018-04894-2  0.578
2018 Chen EM, Quijano AR, Seo YE, Jackson C, Josowitz AD, Noorbakhsh S, Merlettini A, Sundaram RK, Focarete ML, Jiang Z, Bindra RS, Saltzman WM. Biodegradable PEG-poly(ω-pentadecalactone-co-p-dioxanone) nanoparticles for enhanced and sustained drug delivery to treat brain tumors. Biomaterials. 178: 193-203. PMID 29936153 DOI: 10.1016/J.Biomaterials.2018.06.024  0.417
2018 Tietjen GT, Bracaglia LG, Saltzman WM, Pober JS. Focus on Fundamentals: Achieving Effective Nanoparticle Targeting. Trends in Molecular Medicine. PMID 29884540 DOI: 10.1016/J.Molmed.2018.05.003  0.377
2018 Jiang Y, Gaudin A, Zhang J, Agarwal T, Song E, Kauffman AC, Tietjen GT, Wang Y, Jiang Z, Cheng CJ, Saltzman WM. A "top-down" approach to actuate poly(amine-co-ester) terpolymers for potent and safe mRNA delivery. Biomaterials. 176: 122-130. PMID 29879653 DOI: 10.1016/J.Biomaterials.2018.05.043  0.636
2018 Ricciardi AS, Quijano E, Putman R, Saltzman WM, Glazer PM. Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing. Molecules (Basel, Switzerland). 23. PMID 29534473 DOI: 10.3390/Molecules23030632  0.531
2017 Seo YE, Bu T, Saltzman WM. Nanomaterials for convection-enhanced delivery of agents to treat brain tumors. Current Opinion in Biomedical Engineering. 4: 1-12. PMID 29333521 DOI: 10.1016/J.Cobme.2017.09.002  0.31
2017 Quijano E, Bahal R, Ricciardi A, Saltzman WM, Glazer PM. 
Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities
. The Yale Journal of Biology and Medicine. 90: 583-598. PMID 29259523  0.508
2017 Gupta A, Quijano E, Liu Y, Bahal R, Scanlon SE, Song E, Hsieh WC, Braddock DE, Ly DH, Saltzman WM, Glazer PM. Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy. Molecular Therapy. Nucleic Acids. 9: 111-119. PMID 29246289 DOI: 10.1016/J.Omtn.2017.09.001  0.523
2017 Tietjen GT, Hosgood SA, DiRito J, Cui J, Deep D, Song E, Kraehling JR, Piotrowski-Daspit AS, Kirkiles-Smith NC, Al-Lamki R, Thiru S, Bradley JA, Saeb-Parsy K, Bradley JR, Nicholson ML, ... Saltzman WM, et al. Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys. Science Translational Medicine. 9. PMID 29187644 DOI: 10.1126/Scitranslmed.Aam6764  0.404
2017 Chi DL, Song E, Gaudin A, Saltzman WM. Improved threshold selection for the determination of volume of distribution of nanoparticles administered by convection-enhanced delivery. Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society. PMID 28927549 DOI: 10.1016/J.Compmedimag.2017.08.001  0.318
2017 Mohideen M, Quijano E, Song E, Deng Y, Panse G, Zhang W, Clark MR, Saltzman WM. Degradable bioadhesive nanoparticles for prolonged intravaginal delivery and retention of elvitegravir. Biomaterials. 144: 144-154. PMID 28829952 DOI: 10.1016/J.Biomaterials.2017.08.029  0.402
2017 Song E, Gaudin A, King AR, Seo YE, Suh HW, Deng Y, Cui J, Tietjen GT, Huttner A, Saltzman WM. Surface chemistry governs cellular tropism of nanoparticles in the brain. Nature Communications. 8: 15322. PMID 28524852 DOI: 10.1038/Ncomms15322  0.4
2017 Tietjen GT, DiRito J, Pober JS, Saltzman WM. Quantitative microscopy-based measurements of circulating nanoparticle concentration using microliter blood volumes. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 28412144 DOI: 10.1016/J.Nano.2017.04.003  0.369
2017 Cocco E, Deng Y, Shapiro EM, Bortolomai I, Lopez S, Lin K, Bellone S, Cui J, Menderes G, Black JD, Schwab CL, Bonazzoli E, Yang F, Predolini F, Zammataro L, ... ... Saltzman WM, et al. Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells. Molecular Cancer Therapeutics. 16: 323-333. PMID 27956521 DOI: 10.1158/1535-7163.Mct-16-0501  0.347
2017 Song E, Gaudin A, King AR, Seo Y, Won P, Suh H, Deng Y, Cui J, Tietjen G, Saltzman WM. Abstract B46: Surface chemistry governs cellular tropism of nanoparticles in the brain Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-B46  0.307
2016 Zhang J, Cui J, Deng Y, Jiang Z, Saltzman WM. Multifunctional Poly(amine-co-ester-co-ortho ester) for Efficient and Safe Gene Delivery. Acs Biomaterials Science & Engineering. 2: 2080-2089. PMID 28649641 DOI: 10.1021/Acsbiomaterials.6B00502  0.391
2016 Glazer PM, Gupta A, Liu Y, Quijano E, Saltzman WM. Chemically Modified Gamma PNAs Targeting microRNA-210 as a Novel Anticancer Therapy With Specificity for Hypoxic Solid Tumors. International Journal of Radiation Oncology, Biology, Physics. 96: E597. PMID 27675118 DOI: 10.1016/J.Ijrobp.2016.06.2125  0.441
2016 Deng Y, Yang F, Cocco E, Song E, Zhang J, Cui J, Mohideen M, Bellone S, Santin AD, Saltzman WM. Improved i.p. drug delivery with bioadhesive nanoparticles. Proceedings of the National Academy of Sciences of the United States of America. PMID 27663731 DOI: 10.1073/Pnas.1523141113  0.365
2016 Gaudin A, Song E, King AR, Saucier-Sawyer JK, Bindra R, Desmaële D, Couvreur P, Saltzman WM. PEGylated squalenoyl-gemcitabine nanoparticles for the treatment of glioblastoma. Biomaterials. 105: 136-144. PMID 27521616 DOI: 10.1016/J.Biomaterials.2016.07.037  0.383
2016 Belinsky GS, Sreekumar B, Andrejecsk JW, Saltzman WM, Gong J, Herzog RI, Lin S, Horsley V, Carpenter TO, Chung C. Pigment epithelium-derived factor restoration increases bone mass and improves bone plasticity in a model of osteogenesis imperfecta type VI via Wnt3a blockade. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27127101 DOI: 10.1096/Fj.201500027R  0.759
2016 Saucier-Sawyer JK, Seo YE, Gaudin A, Quijano E, Song E, Sawyer AJ, Deng Y, Huttner A, Saltzman WM. Distribution of polymer nanoparticles by convection-enhanced delivery to brain tumors. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27063424 DOI: 10.1016/J.Jconrel.2016.04.006  0.665
2016 Moore LB, Sawyer AJ, Saucier-Sawyer J, Saltzman WM, Kyriakides TR. Nanoparticle delivery of miR-223 to attenuate macrophage fusion. Biomaterials. 89: 127-135. PMID 26967647 DOI: 10.1016/J.Biomaterials.2016.02.036  0.632
2016 Gupta A, Bahal R, Gupta M, Glazer PM, Saltzman WM. Nanotechnology for delivery of peptide nucleic acids (PNAs). Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26776051 DOI: 10.1016/J.Jconrel.2016.01.005  0.534
2016 Gupta A, Liu Y, Quijano EE, Saltzman WM, Glazer PM. Abstract 1075: Chemically modified gamma PNAs targeting oncomiR-210 as a potential anticancer therapy Cancer Research. 76: 1075-1075. DOI: 10.1158/1538-7445.Am2016-1075  0.547
2016 King A, Corso C, Bindra R, Saltzman WM. HG-112LOCAL DELIVERY OF RADIOSENSITIZING NANOPARTICLES FOR THE TREATMENT OF PEDIATRIC BRAINSTEM GLIOMAS Neuro-Oncology. 18: iii74.3-iii74. DOI: 10.1093/Neuonc/Now073.108  0.35
2015 Gavrilov K, Seo YE, Tietjen GT, Cui J, Cheng CJ, Saltzman WM. Enhancing potency of siRNA targeting fusion genes by optimization outside of target sequence. Proceedings of the National Academy of Sciences of the United States of America. 112: E6597-605. PMID 26627251 DOI: 10.1073/Pnas.1517039112  0.359
2015 Steinbach JM, Seo YE, Saltzman WM. Cell penetrating peptide-modified poly(lactic-co-glycolic acid) nanoparticles with enhanced cell internalization. Acta Biomaterialia. PMID 26602822 DOI: 10.1016/J.Actbio.2015.11.029  0.392
2015 Ediriwickrema A, Saltzman WM. Nanotherapy for Cancer: Targeting and Multifunctionality in the Future of Cancer Therapies. Acs Biomaterials Science & Engineering. 1: 64-78. PMID 25984571 DOI: 10.1021/Ab500084G  0.311
2015 Abrahimi P, Chang WG, Kluger MS, Qyang Y, Tellides G, Saltzman WM, Pober JS. Efficient Gene Disruption in Cultured Primary Human Endothelial Cells by CRISPR/Cas9. Circulation Research. 117: 121-8. PMID 25940550 DOI: 10.1161/Circresaha.117.306290  0.308
2015 McNeer NA, Anandalingam K, Fields RJ, Caputo C, Kopic S, Gupta A, Quijano E, Polikoff L, Kong Y, Bahal R, Geibel JP, Glazer PM, Saltzman WM, Egan ME. Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium. Nature Communications. 6: 6952. PMID 25914116 DOI: 10.1038/Ncomms7952  0.802
2015 Andrejecsk JW, Chang WG, Pober JS, Saltzman WM. Controlled protein delivery in the generation of microvascular networks. Drug Delivery and Translational Research. 5: 75-88. PMID 25767747 DOI: 10.1007/S13346-012-0122-Y  0.776
2015 Cheng CJ, Tietjen GT, Saucier-Sawyer JK, Saltzman WM. A holistic approach to targeting disease with polymeric nanoparticles. Nature Reviews. Drug Discovery. 14: 239-47. PMID 25598505 DOI: 10.1038/Nrd4503  0.373
2015 Cheng CJ, Bahal R, Babar IA, Pincus Z, Barrera F, Liu C, Svoronos A, Braddock DT, Glazer PM, Engelman DM, Saltzman WM, Slack FJ. MicroRNA silencing for cancer therapy targeted to the tumour microenvironment. Nature. 518: 107-10. PMID 25409146 DOI: 10.1038/Nature13905  0.537
2015 Strohbehn G, Coman D, Han L, Ragheb RR, Fahmy TM, Huttner AJ, Hyder F, Piepmeier JM, Saltzman WM, Zhou J. Imaging the delivery of brain-penetrating PLGA nanoparticles in the brain using magnetic resonance. Journal of Neuro-Oncology. 121: 441-9. PMID 25403507 DOI: 10.1007/S11060-014-1658-0  0.367
2015 Fields RJ, Quijano E, McNeer NA, Caputo C, Bahal R, Anandalingam K, Egan ME, Glazer PM, Saltzman WM. Modified poly(lactic-co-glycolic acid) nanoparticles for enhanced cellular uptake and gene editing in the lung. Advanced Healthcare Materials. 4: 361-6. PMID 25156908 DOI: 10.1002/Adhm.201400355  0.795
2015 Cheng CJ, Tietjen GT, Saucier-Sawyer JK, Saltzman WM. Erratum: A holistic approach to targeting disease with polymeric nanoparticles Nature Reviews Drug Discovery. 14: 365-365. DOI: 10.1038/Nrd4633  0.322
2015 Engelman DM, Cheng CJ, Bahal R, Babar IA, Pincus Z, Barrera FN, Liu C, Svoronos A, Braddock DT, Glazer PM, Saltzman WM, Slack FJ. pHLIP® Targeting and Delivery of PNA to Silence MicroRNA in Tumor Cells§ Biophysical Journal. 108: 552a. DOI: 10.1016/J.Bpj.2014.11.3029  0.552
2014 Sirianni RW, Zheng MQ, Patel TR, Shafbauer T, Zhou J, Saltzman WM, Carson RE, Huang Y. Radiolabeling of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with biotinylated F-18 prosthetic groups and imaging of their delivery to the brain with positron emission tomography. Bioconjugate Chemistry. 25: 2157-65. PMID 25322194 DOI: 10.1021/Bc500315J  0.699
2014 Bahal R, Quijano E, McNeer NA, Liu Y, Bhunia DC, Lopez-Giraldez F, Fields RJ, Saltzman WM, Ly DH, Glazer PM. Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition. Current Gene Therapy. 14: 331-42. PMID 25174576 DOI: 10.2174/1566523214666140825154158  0.787
2014 Ediriwickrema A, Zhou J, Deng Y, Saltzman WM. Multi-layered nanoparticles for combination gene and drug delivery to tumors. Biomaterials. 35: 9343-54. PMID 25112935 DOI: 10.1016/J.Biomaterials.2014.07.043  0.384
2014 Ricciardi AS, McNeer NA, Anandalingam KK, Saltzman WM, Glazer PM. Targeted genome modification via triple helix formation. Methods in Molecular Biology (Clifton, N.J.). 1176: 89-106. PMID 25030921 DOI: 10.1007/978-1-4939-0992-6_8  0.78
2014 Sawyer AJ, Tian W, Saucier-Sawyer JK, Rizk PJ, Saltzman WM, Bellamkonda RV, Kyriakides TR. The effect of inflammatory cell-derived MCP-1 loss on neuronal survival during chronic neuroinflammation. Biomaterials. 35: 6698-706. PMID 24881026 DOI: 10.1016/J.Biomaterials.2014.05.008  0.627
2014 Deng Y, Saucier-Sawyer JK, Hoimes CJ, Zhang J, Seo YE, Andrejecsk JW, Saltzman WM. The effect of hyperbranched polyglycerol coatings on drug delivery using degradable polymer nanoparticles. Biomaterials. 35: 6595-602. PMID 24816286 DOI: 10.1016/J.Biomaterials.2014.04.038  0.804
2014 Weiser JR, Saltzman WM. Controlled release for local delivery of drugs: barriers and models. Journal of Controlled Release : Official Journal of the Controlled Release Society. 190: 664-73. PMID 24801251 DOI: 10.1016/J.Jconrel.2014.04.048  0.348
2014 Devalliere J, Chang WG, Andrejecsk JW, Abrahimi P, Cheng CJ, Jane-wit D, Saltzman WM, Pober JS. Sustained delivery of proangiogenic microRNA-132 by nanoparticle transfection improves endothelial cell transplantation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 908-22. PMID 24221087 DOI: 10.1096/Fj.13-238527  0.801
2014 Look M, Saltzman WM, Craft J, Fahmy TM. The nanomaterial-dependent modulation of dendritic cells and its potential influence on therapeutic immunosuppression in lupus. Biomaterials. 35: 1089-95. PMID 24183697 DOI: 10.1016/J.Biomaterials.2013.10.046  0.405
2014 Engelman DM, An M, Andreev OA, Barrera FN, Bahal R, Bosenberg MW, Cheng C, Glazer PM, Karabadzhak A, Reshetnyak YK, Saltzman WM, Slack FJ, Svoronos AA, Thevenin D. Imaging and Treating Tumors by Targeting their Acidity with Phlip, a Ph-Sensitve Insertion Peptide Biophysical Journal. 106: 231a. DOI: 10.1016/J.Bpj.2013.11.1350  0.528
2013 Schleifman EB, McNeer NA, Jackson A, Yamtich J, Brehm MA, Shultz LD, Greiner DL, Kumar P, Saltzman WM, Glazer PM. Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice. Molecular Therapy. Nucleic Acids. 2: e135. PMID 24253260 DOI: 10.1038/Mtna.2013.59  0.803
2013 Chang WG, Andrejecsk JW, Kluger MS, Saltzman WM, Pober JS. Pericytes modulate endothelial sprouting. Cardiovascular Research. 100: 492-500. PMID 24042014 DOI: 10.1093/Cvr/Cvt215  0.764
2013 Andrejecsk JW, Cui J, Chang WG, Devalliere J, Pober JS, Saltzman WM. Paracrine exchanges of molecular signals between alginate-encapsulated pericytes and freely suspended endothelial cells within a 3D protein gel. Biomaterials. 34: 8899-908. PMID 23973174 DOI: 10.1016/J.Biomaterials.2013.08.008  0.794
2013 Bahal R, McNeer NA, Ly DH, Saltzman WM, Glazer PM. Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5. Artificial Dna, Pna & Xna. 4: 49-57. PMID 23954968 DOI: 10.4161/adna.25628  0.817
2013 Du X, Li W, Gao X, West MB, Saltzman WM, Cheng CJ, Stewart C, Zheng J, Cheng W, Kopke RD. Regeneration of mammalian cochlear and vestibular hair cells through Hes1/Hes5 modulation with siRNA. Hearing Research. 304: 91-110. PMID 23850665 DOI: 10.1016/J.Heares.2013.06.011  0.415
2013 Zhou J, Patel TR, Sirianni RW, Strohbehn G, Zheng MQ, Duong N, Schafbauer T, Huttner AJ, Huang Y, Carson RE, Zhang Y, Sullivan DJ, Piepmeier JM, Saltzman WM. Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 110: 11751-6. PMID 23818631 DOI: 10.1073/Pnas.1304504110  0.708
2013 Martin DT, Hoimes CJ, Kaimakliotis HZ, Cheng CJ, Zhang K, Liu J, Wheeler MA, Kelly WK, Tew GN, Saltzman WM, Weiss RM. Nanoparticles for urothelium penetration and delivery of the histone deacetylase inhibitor belinostat for treatment of bladder cancer. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 1124-34. PMID 23764660 DOI: 10.1016/J.Nano.2013.05.017  0.372
2013 Sirianni RW, Zheng MQ, Saltzman WM, Huang Y, Carson RE. Direct, quantitative, and noninvasive imaging of the transport of active agents through intact brain with positron emission tomography. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 15: 596-605. PMID 23624949 DOI: 10.1007/S11307-013-0636-9  0.671
2013 Kobsa S, Kristofik NJ, Sawyer AJ, Bothwell AL, Kyriakides TR, Saltzman WM. An electrospun scaffold integrating nucleic acid delivery for treatment of full-thickness wounds. Biomaterials. 34: 3891-901. PMID 23453058 DOI: 10.1016/J.Biomaterials.2013.02.016  0.782
2013 Hoimes CJ, Martin DT, Kaimakliotis HK, Cheng CJ, Kelly WK, Tew GN, Wheeler M, Weiss RM, Saltzman WM. A novel polymer-coated nanoparticle (NP) for urothelium penetration and drug delivery. Journal of Clinical Oncology. 31: e15543-e15543. DOI: 10.1200/Jco.2013.31.15_Suppl.E15543  0.383
2013 Strohbehn GW, Atsina K, Patel TR, Piepmeier JM, Zhou J, Saltzman WM. Abstract A86: Preclinical refinement of a highly-penetrative polymeric nanoparticle drug delivery system for the treatment of glioblastoma multiforme. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A86  0.42
2013 Aaberg-Jessen C, Fogh L, Halle B, Jensen V, Brunner N, Kristensen BW, Abe T, Momii Y, Watanabe J, Morisaki I, Natsume A, Wakabayashi T, Fujiki M, Aldaz B, Fabius AWM, ... ... Saltzman WM, et al. EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY Neuro-Oncology. 15: iii37-iii61. DOI: 10.1093/Neuonc/Not176  0.741
2013 Liu J, Jiang Z, Yang Z, Zhang X, Luo X, Jiang Q, Saltzman WM. Enzymatic synthesis of poly(amine-co-esters) for gene delivery Journal of Controlled Release. 172: e106-e107. DOI: 10.1016/J.Jconrel.2013.08.260  0.326
2013 Svoronos AA, Cheng CJ, Barrera FN, Saltzman WM, Bosenberg MW, Engelman DM. Targeting of Melanoma by pH (Low) Insertion Peptide (pHLIP) Biophysical Journal. 104: 677a. DOI: 10.1016/J.Bpj.2012.11.3740  0.303
2012 Fields RJ, Cheng CJ, Quijano E, Weller C, Kristofik N, Duong N, Hoimes C, Egan ME, Saltzman WM. Surface modified poly(β amino ester)-containing nanoparticles for plasmid DNA delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 164: 41-8. PMID 23041278 DOI: 10.1016/J.Jconrel.2012.09.020  0.786
2012 Steinbach JM, Weller CE, Booth CJ, Saltzman WM. Polymer nanoparticles encapsulating siRNA for treatment of HSV-2 genital infection. Journal of Controlled Release : Official Journal of the Controlled Release Society. 162: 102-10. PMID 22705461 DOI: 10.1016/J.Jconrel.2012.06.008  0.397
2012 Babar IA, Cheng CJ, Booth CJ, Liang X, Weidhaas JB, Saltzman WM, Slack FJ. Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 109: E1695-704. PMID 22685206 DOI: 10.1073/Pnas.1201516109  0.3
2012 Cheng CJ, Saltzman WM. Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing. Molecular Pharmaceutics. 9: 1481-8. PMID 22482958 DOI: 10.1021/Mp300081S  0.409
2012 Zhou J, Atsina KB, Himes BT, Strohbehn GW, Saltzman WM. Novel delivery strategies for glioblastoma. Cancer Journal (Sudbury, Mass.). 18: 89-99. PMID 22290262 DOI: 10.1097/Ppo.0B013E318244D8Ae  0.618
2012 Patel T, Zhou J, Piepmeier JM, Saltzman WM. Polymeric nanoparticles for drug delivery to the central nervous system. Advanced Drug Delivery Reviews. 64: 701-5. PMID 22210134 DOI: 10.1016/J.Addr.2011.12.006  0.409
2012 Zhou J, Liu J, Cheng CJ, Patel TR, Weller CE, Piepmeier JM, Jiang Z, Saltzman WM. Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery. Nature Materials. 11: 82-90. PMID 22138789 DOI: 10.1038/Nmat3187  0.348
2012 Zhou J, Patel TR, Fu M, Bertram JP, Saltzman WM. Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors. Biomaterials. 33: 583-91. PMID 22014944 DOI: 10.1016/J.Biomaterials.2011.09.061  0.425
2012 Strohbehn GW, Zhou J, Fu M, Patel TR, Piepmeier JM, Saltzman WM. Abstract A21: High-throughput small molecule screening of genetically diverse glioblastoma stem cells Cancer Research. 72. DOI: 10.1158/1538-7445.Csb12-A21  0.323
2012 Cocco E, Bellone S, Roque D, Guzzo F, Gasparrini S, Pecorelli S, Silasi D, Azodi M, Ratner E, Ruterford T, Schwartz P, Weller CE, Saltzman WM, Santin AD. Abstract 364: In vivo targeting of CD44+ ovarian cancer stem cells (CSC) by Clostridium Perfringens Enterotoxin binding domain (CPE-peptide) conjugated to poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NP) Cancer Research. 72: 364-364. DOI: 10.1158/1538-7445.Am2012-364  0.345
2011 Blum JS, Weller CE, Booth CJ, Babar IA, Liang X, Slack FJ, Saltzman WM. Prevention of K-Ras- and Pten-mediated intravaginal tumors by treatment with camptothecin-loaded PLGA nanoparticles. Drug Delivery and Translational Research. 1: 383-394. PMID 25419505 DOI: 10.1007/S13346-011-0038-Y  0.356
2011 Cu Y, Booth CJ, Saltzman WM. In vivo distribution of surface-modified PLGA nanoparticles following intravaginal delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 156: 258-64. PMID 21763739 DOI: 10.1016/J.Jconrel.2011.06.036  0.791
2011 Park J, Mattessich T, Jay SM, Agawu A, Saltzman WM, Fahmy TM. Enhancement of surface ligand display on PLGA nanoparticles with amphiphilic ligand conjugates. Journal of Controlled Release : Official Journal of the Controlled Release Society. 156: 109-15. PMID 21723893 DOI: 10.1016/J.Jconrel.2011.06.025  0.64
2011 Sawyer AJ, Saucier-Sawyer JK, Booth CJ, Liu J, Patel T, Piepmeier JM, Saltzman WM. Convection-enhanced delivery of camptothecin-loaded polymer nanoparticles for treatment of intracranial tumors. Drug Delivery and Translational Research. 1: 34-42. PMID 21691426 DOI: 10.1007/S13346-010-0001-3  0.707
2011 Cheng CJ, Saltzman WM. Enhanced siRNA delivery into cells by exploiting the synergy between targeting ligands and cell-penetrating peptides. Biomaterials. 32: 6194-203. PMID 21664689 DOI: 10.1016/J.Biomaterials.2011.04.053  0.407
2011 Liu J, Jiang Z, Zhang S, Liu C, Gross RA, Kyriakides TR, Saltzman WM. Biodegradation, biocompatibility, and drug delivery in poly(ω-pentadecalactone-co-p-dioxanone) copolyesters. Biomaterials. 32: 6646-54. PMID 21641030 DOI: 10.1016/J.Biomaterials.2011.05.046  0.404
2011 McNeer NA, Schleifman EB, Glazer PM, Saltzman WM. Polymer delivery systems for site-specific genome editing. Journal of Controlled Release : Official Journal of the Controlled Release Society. 155: 312-6. PMID 21620910 DOI: 10.1016/J.Jconrel.2011.05.011  0.796
2011 Hibino N, Villalona G, Pietris N, Duncan DR, Schoffner A, Roh JD, Yi T, Dobrucki LW, Mejias D, Sawh-Martinez R, Harrington JK, Sinusas A, Krause DS, Kyriakides T, Saltzman WM, et al. Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2731-9. PMID 21566209 DOI: 10.1096/Fj.11-182246  0.563
2011 Liu J, Jiang Z, Zhou J, Zhang S, Saltzman WM. Enzyme-synthesized poly(amine-co-esters) as nonviral vectors for gene delivery. Journal of Biomedical Materials Research. Part A. 96: 456-65. PMID 21171165 DOI: 10.1002/Jbm.A.32994  0.386
2011 McNeer NA, Chin JY, Schleifman EB, Fields RJ, Glazer PM, Saltzman WM. Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 172-80. PMID 20859257 DOI: 10.1038/Mt.2010.200  0.813
2011 Prasad S, Cody V, Saucier-Sawyer JK, Saltzman WM, Sasaki CT, Edelson RL, Birchall MA, Hanlon DJ. Polymer nanoparticles containing tumor lysates as antigen delivery vehicles for dendritic cell-based antitumor immunotherapy. Nanomedicine : Nanotechnology, Biology, and Medicine. 7: 1-10. PMID 20692374 DOI: 10.1016/J.Nano.2010.07.002  0.364
2011 Andrejecsk JW, Trivellas M, Maier CL, Pober JS, Saltzman WM. Cellular delivery for vascularization of engineered tissues: Reduction of contraction by mural cells 2011 Ieee 37th Annual Northeast Bioengineering Conference, Nebec 2011. DOI: 10.1109/NEBC.2011.5778700  0.775
2011 Kaimakliotis HZ, Martin DT, Hoimes CJ, Cheng CC, Liu J, Kelly WK, Tew GN, Saltzman WM, Weiss RM. 1358 NANOPARTICLE DELIVERY OF THE HISTONE DEACETYLASE INHIBITOR PXD101 FACILITATES BLADDER CANCER CELL UPTAKE AND CYTOTOXICITY Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.1180  0.344
2011 Martin DT, Steinbach JM, Kaimakliotis HZ, Liu J, Wheeler MA, Hittelman AB, Saltzman WM, Weiss RM. 1055 SURFACE MODIFICATIONS OF POLY(LACTIDE-CO-GLYCOLIDE) NANOPARTICLES CAN INCREASE ITS UPTAKE BY BLADDER CANCER CELLS Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.1092  0.351
2010 Kuo-Haller P, Cu Y, Blum J, Appleton JA, Saltzman WM. Vaccine delivery by polymeric vehicles in the mouse reproductive tract induces sustained local and systemic immunity. Molecular Pharmaceutics. 7: 1585-95. PMID 20698574 DOI: 10.1021/Mp100009E  0.744
2010 Roh JD, Sawh-Martinez R, Brennan MP, Jay SM, Devine L, Rao DA, Yi T, Mirensky TL, Nalbandian A, Udelsman B, Hibino N, Shinoka T, Saltzman WM, Snyder E, Kyriakides TR, et al. Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling. Proceedings of the National Academy of Sciences of the United States of America. 107: 4669-74. PMID 20207947 DOI: 10.1073/Pnas.0911465107  0.691
2010 Lo CT, Van Tassel PR, Saltzman WM. Poly(lactide-co-glycolide) nanoparticle assembly for highly efficient delivery of potent therapeutic agents from medical devices. Biomaterials. 31: 3631-42. PMID 20149428 DOI: 10.1016/J.Biomaterials.2010.01.048  0.683
2010 Jay SM, Shepherd BR, Andrejecsk JW, Kyriakides TR, Pober JS, Saltzman WM. Dual delivery of VEGF and MCP-1 to support endothelial cell transplantation for therapeutic vascularization. Biomaterials. 31: 3054-62. PMID 20110124 DOI: 10.1016/J.Biomaterials.2010.01.014  0.786
2010 Sirianni RW, Olausson P, Chiu AS, Taylor JR, Saltzman WM. The behavioral and biochemical effects of BDNF containing polymers implanted in the hippocampus of rats. Brain Research. 1321: 40-50. PMID 20096671 DOI: 10.1016/J.Brainres.2010.01.041  0.667
2010 Sirianni RW, Jang EH, Miller KM, Saltzman WM. Parameter estimation methodology in a model of hydrophobic drug release from a polymer coating. Journal of Controlled Release : Official Journal of the Controlled Release Society. 142: 474-82. PMID 19958804 DOI: 10.1016/J.Jconrel.2009.11.021  0.681
2010 Cartiera MS, Ferreira EC, Caputo C, Egan ME, Caplan MJ, Saltzman WM. Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin. Molecular Pharmaceutics. 7: 86-93. PMID 19886674 DOI: 10.1021/Mp900138A  0.776
2010 Cu Y, LeMoëllic C, Caplan MJ, Saltzman WM. Ligand-modified gene carriers increased uptake in target cells but reduced DNA release and transfection efficiency. Nanomedicine : Nanotechnology, Biology, and Medicine. 6: 334-43. PMID 19800989 DOI: 10.1016/J.Nano.2009.09.001  0.772
2010 Hoimes CJ, Murelli RP, Kelly WK, Zhang AX, Cheng CJ, Fields RJ, Spiegel DA, Saltzman WM. Effect of vorinostat (V)-loaded PLGA nanoparticles (NP) surface modified with a PSMA ligand on prostate cancer (PC) cells. Journal of Clinical Oncology. 28: e13629-e13629. DOI: 10.1200/Jco.2010.28.15_Suppl.E13629  0.641
2010 Saltzman A, Woodrow K, Wheeler MA, Verma A, Saltzman WM, Weiss RM. 436 EFFECT OF SURVIVIN SIRNA AND VEGF SIRNA COMPLEXED IN NANOPARTICLES ON BLADDER CANCER CELLS AND UROTHELIAL TISSUES Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.507  0.355
2009 Liu J, Jiang Z, Zhang S, Saltzman WM. Poly(omega-pentadecalactone-co-butylene-co-succinate) nanoparticles as biodegradable carriers for camptothecin delivery. Biomaterials. 30: 5707-19. PMID 19632718 DOI: 10.1016/J.Biomaterials.2009.06.061  0.413
2009 Lo CT, Van Tassel PR, Saltzman WM. Simultaneous release of multiple molecules from poly(lactide-co-glycolide) nanoparticles assembled onto medical devices. Biomaterials. 30: 4889-97. PMID 19592089 DOI: 10.1016/J.Biomaterials.2009.05.074  0.663
2009 Jay SM, Saltzman WM. Shining light on a new class of hydrogels. Nature Biotechnology. 27: 543-4. PMID 19513057 DOI: 10.1038/Nbt0609-543  0.552
2009 Woodrow KA, Cu Y, Booth CJ, Saucier-Sawyer JK, Wood MJ, Saltzman WM. Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA. Nature Materials. 8: 526-33. PMID 19404239 DOI: 10.1038/Nmat2444  0.795
2009 Park J, Fong PM, Lu J, Russell KS, Booth CJ, Saltzman WM, Fahmy TM. PEGylated PLGA nanoparticles for the improved delivery of doxorubicin. Nanomedicine : Nanotechnology, Biology, and Medicine. 5: 410-8. PMID 19341815 DOI: 10.1016/J.Nano.2009.02.002  0.4
2009 Cartiera MS, Johnson KM, Rajendran V, Caplan MJ, Saltzman WM. The uptake and intracellular fate of PLGA nanoparticles in epithelial cells. Biomaterials. 30: 2790-8. PMID 19232712 DOI: 10.1016/J.Biomaterials.2009.01.057  0.797
2009 Cu Y, Saltzman WM. Mathematical modeling of molecular diffusion through mucus. Advanced Drug Delivery Reviews. 61: 101-14. PMID 19135488 DOI: 10.1016/J.Addr.2008.09.006  0.746
2009 Cu Y, Saltzman WM. Drug delivery: Stealth particles give mucus the slip. Nature Materials. 8: 11-3. PMID 19096387 DOI: 10.1038/Nmat2347  0.78
2009 Woodrow KA, Wood MJ, Saucier-Sawyer JK, Solbrig C, Saltzman WM. Biodegradable meshes printed with extracellular matrix proteins support micropatterned hepatocyte cultures. Tissue Engineering. Part A. 15: 1169-79. PMID 19072719 DOI: 10.1089/Ten.Tea.2008.0265  0.304
2009 Cu Y, Saltzman WM. Controlled surface modification with poly(ethylene)glycol enhances diffusion of PLGA nanoparticles in human cervical mucus. Molecular Pharmaceutics. 6: 173-81. PMID 19053536 DOI: 10.1021/Mp8001254  0.778
2009 Jay SM, Saltzman WM. Controlled delivery of VEGF via modulation of alginate microparticle ionic crosslinking. Journal of Controlled Release : Official Journal of the Controlled Release Society. 134: 26-34. PMID 19027807 DOI: 10.1016/J.Jconrel.2008.10.019  0.611
2009 Shepherd BR, Jay SM, Saltzman WM, Tellides G, Pober JS. Human aortic smooth muscle cells promote arteriole formation by coengrafted endothelial cells. Tissue Engineering. Part A. 15: 165-73. PMID 18620481 DOI: 10.1089/Ten.Tea.2008.0010  0.605
2009 Gutsche AT, Parsons-Wingerter P, Chand D, Saltzman WM, Saltzman WM, Leong KW. N-acetylglucosamine and adenosine derivatized surfaces for cell culture: 3T3 fibroblast and chicken hepatocyte response. Biotechnology and Bioengineering. 43: 801-9. PMID 18615804 DOI: 10.1002/Bit.260430815  0.407
2009 Jay SM, Shepherd BR, Andrejecsk JW, Kyriakides TR, Pober JS, Saltzman WM. Engineered molecular delivery for control and enhancement of transplanted endothelial cell fate in tissue engineering Bioengineering, Proceedings of the Northeast Conference. DOI: 10.1109/NEBC.2009.4967788  0.798
2008 Sirianni RW, Kremer J, Guler I, Chen YL, Keeley FW, Saltzman WM. Effect of extracellular matrix elements on the transport of paclitaxel through an arterial wall tissue mimic. Biomacromolecules. 9: 2792-8. PMID 18785771 DOI: 10.1021/Bm800571S  0.663
2008 Nelson GN, Roh JD, Mirensky TL, Wang Y, Yi T, Tellides G, Pober JS, Shkarin P, Shapiro EM, Saltzman WM, Papademetris X, Fahmy TM, Breuer CK. Initial evaluation of the use of USPIO cell labeling and noninvasive MR monitoring of human tissue-engineered vascular grafts in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3888-95. PMID 18711027 DOI: 10.1096/Fj.08-107367  0.509
2008 Blum JS, Saltzman WM. High loading efficiency and tunable release of plasmid DNA encapsulated in submicron particles fabricated from PLGA conjugated with poly-L-lysine. Journal of Controlled Release : Official Journal of the Controlled Release Society. 129: 66-72. PMID 18511145 DOI: 10.1016/J.Jconrel.2008.04.002  0.329
2008 Jay SM, Shepherd BR, Bertram JP, Pober JS, Saltzman WM. Engineering of multifunctional gels integrating highly efficient growth factor delivery with endothelial cell transplantation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2949-56. PMID 18450813 DOI: 10.1096/Fj.08-108803  0.641
2008 Kobsa S, Saltzman WM. Bioengineering approaches to controlled protein delivery. Pediatric Research. 63: 513-9. PMID 18427296 DOI: 10.1203/Pdr.0B013E318165F14D  0.786
2008 Roh JD, Nelson GN, Brennan MP, Mirensky TL, Yi T, Hazlett TF, Tellides G, Sinusas AJ, Pober JS, Saltzman WM, Kyriakides TR, Breuer CK. Small-diameter biodegradable scaffolds for functional vascular tissue engineering in the mouse model. Biomaterials. 29: 1454-63. PMID 18164056 DOI: 10.1016/J.Biomaterials.2007.11.041  0.509
2007 Ying V, Haverstick K, Page RL, Saltzman WM. Efficacy of camptothecin and polymer-conjugated camptothecin in tumor spheroids and solid tumors. Journal of Biomaterials Science. Polymer Edition. 18: 1283-99. PMID 17939886 DOI: 10.1163/156856207782177918  0.306
2007 Neeves KB, Sawyer AJ, Foley CP, Saltzman WM, Olbricht WL. Dilation and degradation of the brain extracellular matrix enhances penetration of infused polymer nanoparticles. Brain Research. 1180: 121-32. PMID 17920047 DOI: 10.1016/J.Brainres.2007.08.050  0.687
2007 Roh JD, Nelson GN, Udelsman BV, Brennan MP, Lockhart B, Fong PM, Lopez-Soler RI, Saltzman WM, Breuer CK. Centrifugal seeding increases seeding efficiency and cellular distribution of bone marrow stromal cells in porous biodegradable scaffolds. Tissue Engineering. 13: 2743-9. PMID 17880269 DOI: 10.1089/Ten.2007.0171  0.554
2007 Fong P, Goyal A, Brennan M, Park J, Moss L, Saltzman WM, Breuer CK. Development of PTH eluting microspheres for the treatment of hypoparathyroidism. The Journal of Surgical Research. 143: 195-9. PMID 17720197 DOI: 10.1016/J.Jss.2006.04.009  0.525
2007 Fahmy TM, Fong PM, Park J, Constable T, Saltzman WM. Nanosystems for simultaneous imaging and drug delivery to T cells. The Aaps Journal. 9: E171-80. PMID 17614359 DOI: 10.1208/Aapsj0902019  0.337
2007 Fahmy TM, Schneck JP, Saltzman WM. A nanoscopic multivalent antigen-presenting carrier for sensitive detection and drug delivery to T cells. Nanomedicine : Nanotechnology, Biology, and Medicine. 3: 75-85. PMID 17379171 DOI: 10.1016/J.Nano.2006.11.010  0.318
2006 Sawyer AJ, Piepmeier JM, Saltzman WM. New methods for direct delivery of chemotherapy for treating brain tumors. The Yale Journal of Biology and Medicine. 79: 141-52. PMID 17940624  0.64
2006 Luo D, Saltzman WM. Nonviral gene delivery: thinking of silica. Gene Therapy. 13: 585-6. PMID 17526071 DOI: 10.1038/Sj.Gt.3302662  0.401
2006 Keegan ME, Saltzman WM. Surface-modified biodegradable microspheres for DNA vaccine delivery. Methods in Molecular Medicine. 127: 107-13. PMID 16988450 DOI: 10.1385/1-59745-168-1:107  0.345
2006 Mahoney MJ, Krewson C, Miller J, Saltzman WM. Impact of cell type and density on nerve growth factor distribution and bioactivity in 3-dimensional collagen gel cultures. Tissue Engineering. 12: 1915-27. PMID 16889521 DOI: 10.1089/Ten.2006.12.1915  0.704
2006 Goyal A, Wang Y, Su H, Dobrucki LW, Brennan M, Fong P, Dardik A, Tellides G, Sinusas A, Pober JS, Saltzman WM, Breuer CK. Development of a model system for preliminary evaluation of tissue-engineered vascular conduits. Journal of Pediatric Surgery. 41: 787-91. PMID 16567194 DOI: 10.1016/J.Jpedsurg.2006.02.019  0.539
2006 Neeves KB, Lo CT, Foley CP, Saltzman WM, Olbricht WL. Fabrication and characterization of microfluidic probes for convection enhanced drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 111: 252-62. PMID 16476500 DOI: 10.1016/J.Jconrel.2005.11.018  0.586
2006 Shen H, Ackerman AL, Cody V, Giodini A, Hinson ER, Cresswell P, Edelson RL, Saltzman WM, Hanlon DJ. Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles Immunology. 117: 78-88. PMID 16423043 DOI: 10.1111/J.1365-2567.2005.02268.X  0.326
2006 Brennan M, Fong P, Goyal A, Saltzman W, Breuer C. Osteopontin eluting microspheres decrease calcification in tissue engineered heart valves Journal of Surgical Research. 130: 292. DOI: 10.1016/J.Jss.2005.11.379  0.445
2005 Anthony T, Fong P, Goyal A, Saltzman WM, Moss RL, Breuer C. Development of a parathyroid hormone-controlled release system as a potential surgical treatment for hypoparathyroidism. Journal of Pediatric Surgery. 40: 81-5. PMID 15868563 DOI: 10.1016/J.Jpedsurg.2004.09.005  0.514
2005 Gemeinhart RA, Luo D, Saltzman WM. Cellular fate of a modular DNA delivery system mediated by silica nanoparticles. Biotechnology Progress. 21: 532-7. PMID 15801794 DOI: 10.1021/Bp049648W  0.72
2005 Tan J, Gemeinhart RA, Ma M, Saltzman WM. Improved cell adhesion and proliferation on synthetic phosphonic acid-containing hydrogels. Biomaterials. 26: 3663-71. PMID 15621257 DOI: 10.1016/J.Biomaterials.2004.09.053  0.68
2005 Mahoney MJ, Chen RR, Tan J, Saltzman WM. The influence of microchannels on neurite growth and architecture. Biomaterials. 26: 771-8. PMID 15350782 DOI: 10.1016/J.Biomaterials.2004.03.015  0.671
2005 Fahmy TM, Fong PM, Goyal A, Saltzman WM. Targeted for drug delivery Materials Today. 8: 18-26. DOI: 10.1016/S1369-7021(05)71033-6  0.412
2004 Fleming AB, Haverstick K, Saltzman WM. In vitro cytotoxicity and in vivo distribution after direct delivery of PEG-camptothecin conjugates to the rat brain. Bioconjugate Chemistry. 15: 1364-75. PMID 15546204 DOI: 10.1021/Bc034180O  0.358
2004 Shen H, Tan J, Saltzman WM. Surface-mediated gene transfer from nanocomposites of controlled texture. Nature Materials. 3: 569-74. PMID 15258575 DOI: 10.1038/Nmat1179  0.324
2004 Stroh M, Zipfel WR, Williams RM, Ma SC, Webb WW, Saltzman WM. Multiphoton microscopy guides neurotrophin modification with poly(ethylene glycol) to enhance interstitial diffusion. Nature Materials. 3: 489-94. PMID 15208704 DOI: 10.1038/Nmat1159  0.575
2004 Luo D, Han E, Belcheva N, Saltzman WM. A self-assembled, modular DNA delivery system mediated by silica nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 95: 333-41. PMID 14980781 DOI: 10.1016/J.Jconrel.2003.11.019  0.483
2004 Keegan ME, Falcone JL, Leung TC, Saltzman WM. Biodegradable microspheres with enhanced capacity for covalently bound surface ligands Macromolecules. 37: 9779-9784. DOI: 10.1021/Ma049470U  0.365
2004 Goyal A, Anthony T, Fong P, Park J, Saltzman W, Breuer C. Calcium sensitive feedback release of parathyroid hormone as a potential treatment of hypoparathyroidism Journal of Surgical Research. 121: 304. DOI: 10.1016/J.Jss.2004.07.123  0.462
2003 Keegan ME, Whittum-Hudson JA, Saltzman WM. Biomimetic design in microparticulate vaccines Biomaterials. 24: 4435-4443. PMID 12922154 DOI: 10.1016/S0142-9612(03)00351-X  0.311
2003 Cypes SH, Saltzman WM, Giannelis EP. Organosilicate-polymer drug delivery systems: controlled release and enhanced mechanical properties. Journal of Controlled Release : Official Journal of the Controlled Release Society. 90: 163-9. PMID 12810299 DOI: 10.1016/S0168-3659(03)00133-0  0.341
2003 Shen H, Goldberg E, Saltzman WM. Gene expression and mucosal immune responses after vaginal DNA immunization in mice using a controlled delivery matrix. Journal of Controlled Release : Official Journal of the Controlled Release Society. 86: 339-48. PMID 12526829 DOI: 10.1016/S0168-3659(02)00354-1  0.317
2003 Chiellini F, Bizzarri R, Ober CK, Schmaljiohann D, Yu T, Saltzman WM, Solaro R, Chiellini E. Surface patterning and biological evaluation of semi-interpenetrated poly(HEMA)/poly(alkyl β-malolactonate)s Macromolecular Symposia. 197: 369-379. DOI: 10.1002/Masy.200350732  0.301
2002 Saltzman WM, Olbricht WL. Building drug delivery into tissue engineering. Nature Reviews. Drug Discovery. 1: 177-86. PMID 12120502 DOI: 10.1038/Nrd744  0.359
2002 Fleming AB, Saltzman WM. Pharmacokinetics of the carmustine implant. Clinical Pharmacokinetics. 41: 403-19. PMID 12074689 DOI: 10.2165/00003088-200241060-00002  0.335
2002 Luo D, Haverstick K, Belcheva N, Han E, Saltzman WM. Poly(ethylene glycol)-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery Macromolecules. 35: 3456-3462. DOI: 10.1021/Ma0106346  0.457
2001 Mahoney MJ, Saltzman WM. Transplantation of brain cells assembled around a programmable synthetic microenvironment. Nature Biotechnology. 19: 934-9. PMID 11581658 DOI: 10.1038/Nbt1001-934  0.71
2001 Fleming AB, Saltzman WM. Simultaneous delivery of an active protein and neutralizing antibody: creation of separated regions of biological activity. Journal of Controlled Release : Official Journal of the Controlled Release Society. 70: 29-36. PMID 11166405 DOI: 10.1016/S0168-3659(00)00318-7  0.301
2000 Luo D, Saltzman WM. Enhancement of transfection by physical concentration of DNA at the cell surface. Nature Biotechnology. 18: 893-5. PMID 10932162 DOI: 10.1038/78523  0.363
2000 Luo D, Saltzman WM. Synthetic DNA delivery systems. Nature Biotechnology. 18: 33-7. PMID 10625387 DOI: 10.1038/71889  0.326
1999 Luo D, Woodrow-Mumford K, Belcheva N, Saltzman WM. Controlled DNA delivery systems. Pharmaceutical Research. 16: 1300-8. PMID 10468035 DOI: 10.1023/A:1014870102295  0.467
1999 Tan J, Saltzman WM. Influence of synthetic polymers on neutrophil migration in three-dimensional collagen gels. Journal of Biomedical Materials Research. 46: 465-74. PMID 10398007 DOI: 10.1002/(Sici)1097-4636(19990915)46:4<465::Aid-Jbm4>3.0.Co;2-N  0.309
1999 Saltzman WM, Mak MW, Mahoney MJ, Duenas ET, Cleland JL. Intracranial delivery of recombinant nerve growth factor: release kinetics and protein distribution for three delivery systems. Pharmaceutical Research. 16: 232-40. PMID 10100308  0.677
1999 Mahoney MJ, Saltzman WM. Cultures of cells from fetal rat brain: methods to control composition, morphology, and biochemical activity. Biotechnology and Bioengineering. 62: 461-7. PMID 9921155 DOI: 10.1002/(Sici)1097-0290(19990220)62:4<461::Aid-Bit9>3.0.Co;2-A  0.686
1998 Haller MF, Saltzman WM. Nerve growth factor delivery systems Journal of Controlled Release. 53: 1-6. PMID 9741908 DOI: 10.1016/S0168-3659(97)00232-0  0.314
1998 Haller MF, Saltzman WM. Localized delivery of proteins in the brain: Can transport be customized? Pharmaceutical Research. 15: 377-385. PMID 9563066 DOI: 10.1023/A:1011911912174  0.327
1998 Baldwin SP, Saltzman WM. Materials for protein delivery in tissue engineering Advanced Drug Delivery Reviews. 33: 71-86. DOI: 10.1016/S0169-409X(98)00021-0  0.377
1997 Saltzman WM, Fung LK. Polymeric implants for cancer chemotherapy. Advanced Drug Delivery Reviews. 26: 209-230. PMID 10837544 DOI: 10.1016/S0169-409X(97)00036-7  0.337
1997 Wyatt TL, Saltzman WM. Protein delivery from nondegradable polymer matrices Pharmaceutical Biotechnology. 10: 119-137. PMID 9160370 DOI: 10.1007/0-306-46803-4_4  0.304
1996 Mahoney MJ, Saltzman WM. Controlled release of proteins to tissue transplants for the treatment of neurodegenerative disorders. Journal of Pharmaceutical Sciences. 85: 1276-81. PMID 8961138 DOI: 10.1021/Js9601602  0.723
1996 Kuo PYP, Saltzman WM. Novel systems for controlled delivery of macromolecules Critical Reviews in Eukaryotic Gene Expression. 6: 59-73. PMID 8882307 DOI: 10.1615/Critreveukargeneexpr.V6.I1.40  0.381
1996 Krewson CE, Saltzman WM. Nerve growth factor delivery and cell aggregation enhance choline acetyltransferase activity after neural transplantation Tissue Engineering. 2: 183-196. DOI: 10.1089/Ten.1996.2.183  0.335
1996 Parkhurst MR, Saltzman WM. Controlled delivery of antibodies against leukocyte adhesion molecules from polymer matrices Journal of Controlled Release. 42: 273-288. DOI: 10.1016/0168-3659(96)01464-2  0.317
1996 Dai W, Saltzman WM. Fibroblast aggregation by suspension with conjugates of poly(ethylene glycol) and RGD Biotechnology and Bioengineering. 50: 349-356. DOI: 10.1002/(Sici)1097-0290(19960520)50:4<349::Aid-Bit1>3.0.Co;2-L  0.33
1995 Mak M, Fung L, Strasser JF, Saltzman WM. Distribution of drugs following controlled delivery to the brain interstitium Journal of Neuro-Oncology. 26: 91-102. PMID 8787851 DOI: 10.1007/Bf01060215  0.333
1995 Krewson CE, Klarman ML, Saltzman WM. Distribution of nerve growth factor following direct delivery to brain interstitium Brain Research. 680: 196-206. PMID 7663977 DOI: 10.1016/0006-8993(95)00261-N  0.31
1994 Dang W, Saltzman WM. Controlled release of macromolecules from a degradable polyanhydride matrix Journal of Biomaterials Science. Polymer Edition. 6: 297-311. PMID 7527250 DOI: 10.1163/156856294X00374  0.325
1993 Beaty CE, Saltzman WM. Controlled growth factor delivery induces differential neurite outgrowth in three-dimensional cell cultures Journal of Controlled Release. 24: 15-23. DOI: 10.1016/0168-3659(93)90165-2  0.336
1992 Sherwood JK, Dause RB, Saltzman WM. Controlled antibody delivery systems. Nature Biotechnology. 10: 1446-1449. PMID 1369022 DOI: 10.1038/Nbt1192-1446  0.329
1991 Saltzman WM, Parsons-Wingerter P, Leong KW, Lin S. Fibroblast and hepatocyte behavior on synthetic polymer surfaces Journal of Biomedical Materials Research. 25: 741-759. PMID 1874758 DOI: 10.1002/Jbm.820250605  0.481
1991 Saltzman WM, Radomsky ML. Drugs released from polymers: diffusion and elimination in brain tissue Chemical Engineering Science. 46: 2429-2444. DOI: 10.1016/0009-2509(91)80036-X  0.34
1990 Powell EM, Sobarzo MR, Saltzman WM. Controlled release of nerve growth factor from a polymeric implant. Brain Research. 515: 309-11. PMID 2357568 DOI: 10.1016/0006-8993(90)90612-F  0.304
1989 Freese A, Sabel BA, Saltzman WM, During MJ, Langer R. Controlled release of dopamine from a polymeric brain implant: in vitro characterization. Experimental Neurology. 103: 234-8. PMID 2920789 DOI: 10.1016/0014-4886(89)90047-2  0.406
1989 During MJ, Freese A, Sabel BA, Saltzman WM, Deutch A, Roth RH, Langer R. Controlled release of dopamine from a polymeric brain implant: in vivo characterization. Annals of Neurology. 25: 351-6. PMID 2634975 DOI: 10.1002/Ana.410250406  0.379
1989 Zydney AL, Saltzman WM, Colton CK. Hydraulic resistance of red cell beds in an unstirred filtration cell Chemical Engineering Science. 44: 147-159. DOI: 10.1016/0009-2509(89)85240-6  0.482
1988 Vacanti JP, Morse MA, Saltzman WM, Domb AJ, Perez-Atayde A, Langer R. Selective cell transplantation using bioabsorbable artificial polymers as matrices Journal of Pediatric Surgery. 23: 3-9. PMID 2895175 DOI: 10.1016/S0022-3468(88)80529-3  0.436
1988 Mullon CJP, Saltzman WM, Langer R. Computer rased visualization for quantitative and qualitative analysis of the distribution of matrix-bound proteins Bio/Technology. 6: 927-929. DOI: 10.1038/Nbt0888-927  0.364
1988 Mathiowitz E, Saltzman WM, Domb A, Dor P, Langer R. Polyanhydride microspheres as drug carriers. II. Microencapsulation by solvent removal Journal of Applied Polymer Science. 35: 755-774. DOI: 10.1002/App.1988.070350316  0.332
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