H. Tom Soh - Publications

Affiliations: 
Electrical Engineering Stanford University, Palo Alto, CA 
 University of California, Santa Barbara, Santa Barbara, CA, United States 

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Park CH, Thompson IAP, Newman SS, Hein LA, Lian X, Fu K, Pan J, Eisenstein M, Soh HT. Real-Time Spatiotemporal Measurement of Extracellular Signaling Molecules Using An Aptamer Switch-Conjugated Hydrogel Matrix. Advanced Materials (Deerfield Beach, Fla.). e2306704. PMID 37947789 DOI: 10.1002/adma.202306704  0.528
2023 Park KS, Choi A, Kim HJ, Park I, Eom MS, Yeo SG, Son RG, Park TI, Lee G, Soh HT, Hong Y, Pack SP. Ultra-sensitive label-free SERS biosensor with high-throughput screened DNA aptamer for universal detection of SARS-CoV-2 variants from clinical samples. Biosensors & Bioelectronics. 228: 115202. PMID 36940632 DOI: 10.1016/j.bios.2023.115202  0.304
2023 Wu D, Feagin T, Mage P, Rangel A, Wan L, Kong D, Li A, Coller J, Eisenstein M, Soh H. Flow-Cell-Based Technology for Massively Parallel Characterization of Base-Modified DNA Aptamers. Analytical Chemistry. PMID 36693249 DOI: 10.1021/acs.analchem.1c04777  0.325
2022 Kesler V, Fu K, Chen Y, Park CH, Eisenstein M, Murmann B, Soh HT. Tailoring electrode surface charge to achieve discrimination and quantification of chemically similar small molecules with electrochemical aptamers. Advanced Functional Materials. 33. PMID 36819738 DOI: 10.1002/adfm.202208534  0.556
2022 Hariri AA, Newman SS, Tan S, Mamerow D, Adams AM, Maganzini N, Zhong BL, Eisenstein M, Dunn AR, Soh HT. Improved immunoassay sensitivity and specificity using single-molecule colocalization. Nature Communications. 13: 5359. PMID 36097164 DOI: 10.1038/s41467-022-32796-x  0.305
2022 Wu D, Gordon CKL, Shin JH, Eisenstein M, Soh HT. Directed Evolution of Aptamer Discovery Technologies. Accounts of Chemical Research. 55: 685-695. PMID 35130439 DOI: 10.1021/acs.accounts.1c00724  0.325
2020 Wilson BD, Soh HT. Re-Evaluating the Conventional Wisdom about Binding Assays. Trends in Biochemical Sciences. PMID 32402748 DOI: 10.1016/J.Tibs.2020.04.005  0.386
2019 Wilson BD, Hariri AA, Thompson IAP, Eisenstein M, Soh HT. Independent control of the thermodynamic and kinetic properties of aptamer switches. Nature Communications. 10: 5079. PMID 31699984 DOI: 10.1038/S41467-019-13137-X  0.342
2019 Kang B, Park S, Soh HT, Oh SS. A Dual-sensing DNA Nanostructure with an Ultra-broad Detection Range. Acs Sensors. PMID 31547650 DOI: 10.1021/acssensors.9b01503  0.328
2019 Wilson BD, Eisenstein MS, Soh HT. High-Fidelity Nanopore Sequencing of Ultra-Short DNA Targets. Analytical Chemistry. PMID 31038923 DOI: 10.1021/Acs.Analchem.9B00856  0.378
2018 Gotrik M, Sekhon G, Saurabh S, Nakamoto M, Eisenstein M, Soh HT. Direct Selection of Fluorescence-Enhancing RNA Aptamers. Journal of the American Chemical Society. PMID 29505267 DOI: 10.1021/Jacs.7B10724  0.358
2018 McGivney JB, Csordas AT, Walker FM, Bagley ER, Gruber EM, Mage PL, Casas-Finet J, Nakamoto MA, Eisenstein M, Larkin CJ, Strouse RJ, Soh HT. Strategy for Generating Sequence-Defined Aptamer Reagent Sets for Detecting Protein Contaminants in Biotherapeutics. Analytical Chemistry. PMID 29436820 DOI: 10.1021/Acs.Analchem.7B04775  0.414
2017 Chuong TT, Pallaoro A, Chaves CA, Li Z, Lee J, Eisenstein M, Stucky GD, Moskovits M, Soh HT. Dual-reporter SERS-based biomolecular assay with reduced false-positive signals. Proceedings of the National Academy of Sciences of the United States of America. PMID 28784766 DOI: 10.1073/Pnas.1700317114  0.395
2016 Wang J, Yu J, Yang Q, McDermott J, Scott A, Vukovich M, Lagrois R, Gong Q, Greenleaf W, Eisenstein M, Ferguson BS, Soh HT. Multiparameter Particle Display (MPPD): A Quantitative Screening Method for the Discovery of Highly Specific Aptamers. Angewandte Chemie (International Ed. in English). PMID 27933702 DOI: 10.1002/Anie.201608880  0.414
2016 Csordas AT, Jørgensen A, Wang J, Gruber E, Gong Q, Bagley ER, Nakamoto MA, Eisenstein M, Soh HT. High-Throughput Discovery of Aptamers for Sandwich Assays. Analytical Chemistry. PMID 27813404 DOI: 10.1021/Acs.Analchem.6B03450  0.457
2016 Gotrik MR, Feagin TA, Csordas AT, Nakamoto MA, Soh HT. Advancements in Aptamer Discovery Technologies. Accounts of Chemical Research. PMID 27526193 DOI: 10.1021/Acs.Accounts.6B00283  0.415
2015 Jakobsson O, Oh SS, Antfolk M, Eisenstein M, Laurell T, Soh HT. Thousand-fold volumetric concentration of live cells with a recirculating acoustofluidic device. Analytical Chemistry. 87: 8497-502. PMID 26226316 DOI: 10.1021/Acs.Analchem.5B01944  0.332
2015 Hsieh K, Ferguson BS, Eisenstein M, Plaxco KW, Soh HT. Integrated electrochemical microsystems for genetic detection of pathogens at the point of care. Accounts of Chemical Research. 48: 911-20. PMID 25785632 DOI: 10.1021/Ar500456W  0.645
2015 Cho M, Oh SS, Nie J, Stewart R, Radeke MJ, Eisenstein M, Coffey PJ, Thomson JA, Soh HT. Array-based discovery of aptamer pairs. Analytical Chemistry. 87: 821-8. PMID 25495696 DOI: 10.1021/Ac504076K  0.431
2014 Oh SS, Lee BF, Leibfarth FA, Eisenstein M, Robb MJ, Lynd NA, Hawker CJ, Soh HT. Synthetic aptamer-polymer hybrid constructs for programmed drug delivery into specific target cells. Journal of the American Chemical Society. 136: 15010-5. PMID 25290917 DOI: 10.1021/Ja5079464  0.346
2014 Walker FM, Ahmad KM, Eisenstein M, Soh HT. Transformation of personal computers and mobile phones into genetic diagnostic systems. Analytical Chemistry. 86: 9236-41. PMID 25223929 DOI: 10.1021/Ac5022419  0.413
2014 Jung YK, Woo MA, Soh HT, Park HG. Aptamer-based cell imaging reagents capable of fluorescence switching. Chemical Communications (Cambridge, England). 50: 12329-32. PMID 25182171 DOI: 10.1039/C4Cc03888F  0.322
2014 Park KS, Oh SS, Soh HT, Park HG. Target-controlled formation of silver nanoclusters in abasic site-incorporated duplex DNA for label-free fluorescence detection of theophylline. Nanoscale. 6: 9977-82. PMID 24901073 DOI: 10.1039/C4Nr00625A  0.392
2014 Jiang P, Meyer S, Hou Z, Propson NE, Soh HT, Thomson JA, Stewart R. MPBind: a Meta-motif-based statistical framework and pipeline to Predict Binding potential of SELEX-derived aptamers. Bioinformatics (Oxford, England). 30: 2665-7. PMID 24872422 DOI: 10.1093/Bioinformatics/Btu348  0.358
2014 Wang J, Gong Q, Maheshwari N, Eisenstein M, Arcila ML, Kosik KS, Soh HT. Particle display: a quantitative screening method for generating high-affinity aptamers. Angewandte Chemie (International Ed. in English). 53: 4796-801. PMID 24644057 DOI: 10.1002/Anie.201309334  0.367
2014 Hsieh K, Mage PL, Csordas AT, Eisenstein M, Soh HT. Simultaneous elimination of carryover contamination and detection of DNA with uracil-DNA-glycosylase-supplemented loop-mediated isothermal amplification (UDG-LAMP). Chemical Communications (Cambridge, England). 50: 3747-9. PMID 24577617 DOI: 10.1039/C4Cc00540F  0.603
2014 Yang AH, Hsieh K, Patterson AS, Ferguson BS, Eisenstein M, Plaxco KW, Soh HT. Accurate zygote-specific discrimination of single-nucleotide polymorphisms using microfluidic electrochemical DNA melting curves. Angewandte Chemie (International Ed. in English). 53: 3163-7. PMID 24520069 DOI: 10.1002/Anie.201310059  0.576
2013 Ferguson BS, Hoggarth DA, Maliniak D, Ploense K, White RJ, Woodward N, Hsieh K, Bonham AJ, Eisenstein M, Kippin TE, Plaxco KW, Soh HT. Real-time, aptamer-based tracking of circulating therapeutic agents in living animals. Science Translational Medicine. 5: 213ra165. PMID 24285484 DOI: 10.1126/Scitranslmed.3007095  0.536
2013 Patterson AS, Hsieh K, Soh HT, Plaxco KW. Electrochemical real-time nucleic acid amplification: towards point-of-care quantification of pathogens. Trends in Biotechnology. 31: 704-12. PMID 24209384 DOI: 10.1016/J.Tibtech.2013.09.005  0.593
2013 Cho M, Soo Oh S, Nie J, Stewart R, Eisenstein M, Chambers J, Marth JD, Walker F, Thomson JA, Soh HT. Quantitative selection and parallel characterization of aptamers. Proceedings of the National Academy of Sciences of the United States of America. 110: 18460-5. PMID 24167271 DOI: 10.1073/Pnas.1315866110  0.394
2013 Meyer S, Maufort JP, Nie J, Stewart R, McIntosh BE, Conti LR, Ahmad KM, Soh HT, Thomson JA. Development of an efficient targeted cell-SELEX procedure for DNA aptamer reagents. Plos One. 8: e71798. PMID 23967247 DOI: 10.1371/Journal.Pone.0071798  0.373
2013 Patterson AS, Heithoff DM, Ferguson BS, Soh HT, Mahan MJ, Plaxco KW. Microfluidic chip-based detection and intraspecies strain discrimination of Salmonella serovars derived from whole blood of septic mice. Applied and Environmental Microbiology. 79: 2302-11. PMID 23354710 DOI: 10.1128/Aem.03882-12  0.415
2012 Yang AH, Soh HT. Acoustophoretic sorting of viable mammalian cells in a microfluidic device. Analytical Chemistry. 84: 10756-62. PMID 23157478 DOI: 10.1021/Ac3026674  0.309
2012 Olson CA, Nie J, Diep J, Al-Shyoukh I, Takahashi TT, Al-Mawsawi LQ, Bolin JM, Elwell AL, Swanson S, Stewart R, Thomson JA, Soh HT, Roberts RW, Sun R. Single-round, multiplexed antibody mimetic design through mRNA display. Angewandte Chemie (International Ed. in English). 51: 12449-53. PMID 23125174 DOI: 10.1002/Anie.201207005  0.309
2012 Ahmad KM, Xiao Y, Soh HT. Selection is more intelligent than design: improving the affinity of a bivalent ligand through directed evolution. Nucleic Acids Research. 40: 11777-83. PMID 23042245 DOI: 10.1093/Nar/Gks899  0.379
2012 Wang J, Rudzinski JF, Gong Q, Soh HT, Atzberger PJ. Influence of target concentration and background binding on in vitro selection of affinity reagents. Plos One. 7: e43940. PMID 22952815 DOI: 10.1371/Journal.Pone.0043940  0.362
2012 Gong Q, Wang J, Ahmad KM, Csordas AT, Zhou J, Nie J, Stewart R, Thomson JA, Rossi JJ, Soh HT. Selection strategy to generate aptamer pairs that bind to distinct sites on protein targets. Analytical Chemistry. 84: 5365-71. PMID 22624874 DOI: 10.1021/Ac300873P  0.406
2012 Hsieh K, Patterson AS, Ferguson BS, Plaxco KW, Soh HT. Rapid, sensitive, and quantitative detection of pathogenic DNA at the point of care through microfluidic electrochemical quantitative loop-mediated isothermal amplification. Angewandte Chemie (International Ed. in English). 51: 4896-900. PMID 22488842 DOI: 10.1002/Anie.201109115  0.62
2012 Bonham AJ, Hsieh K, Ferguson BS, Vallée-Bélisle A, Ricci F, Soh HT, Plaxco KW. Quantification of transcription factor binding in cell extracts using an electrochemical, structure-switching biosensor. Journal of the American Chemical Society. 134: 3346-8. PMID 22313286 DOI: 10.1021/Ja2115663  0.581
2012 White RJ, Kallewaard HM, Hsieh W, Patterson AS, Kasehagen JB, Cash KJ, Uzawa T, Soh HT, Plaxco KW. Wash-free, electrochemical platform for the quantitative, multiplexed detection of specific antibodies. Analytical Chemistry. 84: 1098-103. PMID 22145706 DOI: 10.1021/Ac202757C  0.375
2011 Kogot JM, Zhang Y, Moore SJ, Pagano P, Stratis-Cullum DN, Chang-Yen D, Turewicz M, Pellegrino PM, de Fusco A, Soh HT, Stagliano NE. Screening of peptide libraries against protective antigen of Bacillus anthracis in a disposable microfluidic cartridge. Plos One. 6: e26925. PMID 22140433 DOI: 10.1371/Journal.Pone.0026925  0.334
2011 Zuo X, Xia F, Patterson A, Soh HT, Xiao Y, Plaxco KW. Two-step, PCR-free telomerase detection by using exonuclease III-aided target recycling. Chembiochem : a European Journal of Chemical Biology. 12: 2745-7. PMID 22125097 DOI: 10.1002/Cbic.201100592  0.434
2011 Ahmad KM, Oh SS, Kim S, McClellen FM, Xiao Y, Soh HT. Probing the limits of aptamer affinity with a microfluidic SELEX platform. Plos One. 6: e27051. PMID 22110600 DOI: 10.1371/Journal.Pone.0027051  0.383
2011 Olmsted IR, Xiao Y, Cho M, Csordas AT, Sheehan JH, Meiler J, Soh HT, Bornhop DJ. Measurement of aptamer-protein interactions with back-scattering interferometry. Analytical Chemistry. 83: 8867-70. PMID 22032342 DOI: 10.1021/Ac202823M  0.326
2011 Hsieh K, White RJ, Ferguson BS, Plaxco KW, Xiao Y, Soh HT. Polarity-switching electrochemical sensor for specific detection of single-nucleotide mismatches. Angewandte Chemie (International Ed. in English). 50: 11176-80. PMID 21976312 DOI: 10.1002/Anie.201103482  0.626
2011 Oh SS, Ahmad KM, Cho M, Kim S, Xiao Y, Soh HT. Improving aptamer selection efficiency through volume dilution, magnetic concentration, and continuous washing in microfluidic channels. Analytical Chemistry. 83: 6883-9. PMID 21774453 DOI: 10.1021/Ac201269F  0.415
2011 Olson CA, Adams JD, Takahashi TT, Qi H, Howell SM, Wu TT, Roberts RW, Sun R, Soh HT. Rapid mRNA-display selection of an IL-6 inhibitor using continuous-flow magnetic separation. Angewandte Chemie (International Ed. in English). 50: 8295-8. PMID 21761516 DOI: 10.1002/Anie.201101149  0.364
2011 Ferguson BS, Buchsbaum SF, Wu TT, Hsieh K, Xiao Y, Sun R, Soh HT. Genetic analysis of H1N1 influenza virus from throat swab samples in a microfluidic system for point-of-care diagnostics. Journal of the American Chemical Society. 133: 9129-35. PMID 21561070 DOI: 10.1021/Ja203981W  0.609
2011 Wang J, Liu Y, Teesalu T, Sugahara KN, Kotamrajua VR, Adams JD, Ferguson BS, Gong Q, Oh SS, Csordas AT, Cho M, Ruoslahti E, Xiao Y, Soh HT. Selection of phage-displayed peptides on live adherent cells in microfluidic channels. Proceedings of the National Academy of Sciences of the United States of America. 108: 6909-14. PMID 21486998 DOI: 10.1073/Pnas.1014753108  0.371
2011 Plaxco KW, Soh HT. Switch-based biosensors: a new approach towards real-time, in vivo molecular detection. Trends in Biotechnology. 29: 1-5. PMID 21106266 DOI: 10.1016/J.Tibtech.2010.10.005  0.392
2010 Xiao Y, Dane KY, Uzawa T, Csordas A, Qian J, Soh HT, Daugherty PS, Lagally ET, Heeger AJ, Plaxco KW. Detection of telomerase activity in high concentration of cell lysates using primer-modified gold nanoparticles. Journal of the American Chemical Society. 132: 15299-307. PMID 20932008 DOI: 10.1021/Ja106513F  0.393
2010 Cho M, Xiao Y, Nie J, Stewart R, Csordas AT, Oh SS, Thomson JA, Soh HT. Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing. Proceedings of the National Academy of Sciences of the United States of America. 107: 15373-8. PMID 20705898 DOI: 10.1073/Pnas.1009331107  0.389
2010 Oh SS, Plakos K, Lou X, Xiao Y, Soh HT. In vitro selection of structure-switching, self-reporting aptamers. Proceedings of the National Academy of Sciences of the United States of America. 107: 14053-8. PMID 20660786 DOI: 10.1073/Pnas.1009172107  0.42
2010 Jung YK, Kim TW, Park HG, Soh HT. Specific colorimetric detection of proteins using bidentate aptamer-conjugated polydiacetylene (PDA) liposomes Advanced Functional Materials. 20: 3092-3097. DOI: 10.1002/Adfm.201001008  0.391
2009 Adams JD, Thévoz P, Bruus H, Soh HT. Integrated acoustic and magnetic separation in microfluidic channels. Applied Physics Letters. 95: 254103. PMID 20087428 DOI: 10.1063/1.3275577  0.313
2009 Xiao Y, Lou X, Uzawa T, Plakos KJ, Plaxco KW, Soh HT. An electrochemical sensor for single nucleotide polymorphism detection in serum based on a triple-stem DNA probe. Journal of the American Chemical Society. 131: 15311-6. PMID 19807078 DOI: 10.1021/Ja905068S  0.409
2009 Kim U, Soh HT. Simultaneous sorting of multiple bacterial targets using integrated dielectrophoretic-magnetic activated cell sorter. Lab On a Chip. 9: 2313-8. PMID 19636461 DOI: 10.1039/B903950C  0.383
2009 Ferguson BS, Buchsbaum SF, Swensen JS, Hsieh K, Lou X, Soh HT. Integrated microfluidic electrochemical DNA sensor. Analytical Chemistry. 81: 6503-8. PMID 19586008 DOI: 10.1021/Ac900923E  0.63
2009 Oh SS, Qian J, Lou X, Zhang Y, Xiao Y, Soh HT. Generation of highly specific aptamers via micromagnetic selection. Analytical Chemistry. 81: 5490-5. PMID 19480397 DOI: 10.1021/Ac900759K  0.434
2009 Gerdon AE, Oh SS, Hsieh K, Ke Y, Yan H, Soh HT. Controlled delivery of DNA origami on patterned surfaces. Small (Weinheim An Der Bergstrasse, Germany). 5: 1942-6. PMID 19437465 DOI: 10.1002/Smll.200900442  0.562
2009 Xiao Y, Plakos KJ, Lou X, White RJ, Qian J, Plaxco KW, Soh HT. Fluorescence detection of single-nucleotide polymorphisms with a single, self-complementary, triple-stem DNA probe. Angewandte Chemie (International Ed. in English). 48: 4354-8. PMID 19431180 DOI: 10.1002/Anie.200900369  0.386
2009 Liu Y, Adams JD, Turner K, Cochran FV, Gambhir SS, Soh HT. Controlling the selection stringency of phage display using a microfluidic device. Lab On a Chip. 9: 1033-6. PMID 19350081 DOI: 10.1039/B820985E  0.316
2009 Swensen JS, Xiao Y, Ferguson BS, Lubin AA, Lai RY, Heeger AJ, Plaxco KW, Soh HT. Continuous, real-time monitoring of cocaine in undiluted blood serum via a microfluidic, electrochemical aptamer-based sensor. Journal of the American Chemical Society. 131: 4262-6. PMID 19271708 DOI: 10.1021/Ja806531Z  0.434
2009 Lou X, Qian J, Xiao Y, Viel L, Gerdon AE, Lagally ET, Atzberger P, Tarasow TM, Heeger AJ, Soh HT. Micromagnetic selection of aptamers in microfluidic channels. Proceedings of the National Academy of Sciences of the United States of America. 106: 2989-94. PMID 19202068 DOI: 10.1073/Pnas.0813135106  0.42
2008 Adams JD, Kim U, Soh HT. Multitarget magnetic activated cell sorter. Proceedings of the National Academy of Sciences of the United States of America. 105: 18165-70. PMID 19015523 DOI: 10.1073/Pnas.0809795105  0.355
2008 Kim U, Qian J, Kenrick SA, Daugherty PS, Soh HT. Multitarget dielectrophoresis activated cell sorter. Analytical Chemistry. 80: 8656-61. PMID 18939853 DOI: 10.1021/Ac8015938  0.356
2008 Hsieh K, Ferguson BS, Soh HT. Continuous monitoring of rare water-borne bacteria via dielectrophoresis- enhanced polymerase chain reaction (DEPCR) device 12th International Conference On Miniaturized Systems For Chemistry and Life Sciences - the Proceedings of Microtas 2008 Conference. 405-407.  0.522
2006 Lai RY, Lagally ET, Lee SH, Soh HT, Plaxco KW, Heeger AJ. Rapid, sequence-specific detection of unpurified PCR amplicons via a reusable, electrochemical sensor. Proceedings of the National Academy of Sciences of the United States of America. 103: 4017-21. PMID 16537478 DOI: 10.1073/Pnas.0511325103  0.307
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