Eric Batchelor, Ph.D. - Publications

Affiliations: 
2005 University of Pennsylvania, Philadelphia, PA, United States 

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Yang Z, Hanson RL, Batchelor E. Progress and challenges in understanding the regulation and function of p53 dynamics. Biochemical Society Transactions. PMID 34495325 DOI: 10.1042/BST20210148  0.692
2020 Hanson RL, Batchelor E. Rucaparib Treatment Alters p53 Oscillations in Single Cells to Enhance DNA-Double-Strand-Break-Induced Cell Cycle Arrest. Cell Reports. 33: 108240. PMID 33053351 DOI: 10.1016/j.celrep.2020.108240  0.434
2019 Harton MD, Koh WS, Bunker AD, Singh A, Batchelor E. p53 pulse modulation differentially regulates target gene promoters to regulate cell fate decisions. Molecular Systems Biology. 15: e8685. PMID 31556489 DOI: 10.15252/Msb.20188685  0.546
2019 Koh WS, Porter JR, Batchelor E. Tuning of mRNA stability through altering 3'-UTR sequences generates distinct output expression in a synthetic circuit driven by p53 oscillations. Scientific Reports. 9: 5976. PMID 30979970 DOI: 10.1038/S41598-019-42509-Y  0.45
2019 Hanson RL, Porter JR, Batchelor E. Protein stability of p53 targets determines their temporal expression dynamics in response to p53 pulsing. The Journal of Cell Biology. PMID 30745421 DOI: 10.1083/Jcb.201803063  0.47
2018 Kambach DM, Halim AS, Cauer AG, Sun Q, Tristan CA, Kesarwala AH, Shankavaram U, Batchelor E, Stommel JM. Abstract B097: Dysregulated mevalonate and cholesterol synthesis is a therapeutic vulnerability in glioblastoma Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B097  0.349
2017 House CD, Jordan E, Hernandez L, Ozaki M, James JM, Kim M, Kruhlak MJ, Batchelor E, Elloumi F, Cam MC, Annunziata CM. NF-kB promotes ovarian tumorigenesis via classical pathways supporting proliferative cancer cells and alternative pathways supporting ALDH+ cancer stem-like cells. Cancer Research. PMID 29074539 DOI: 10.1158/0008-5472.Can-17-0366  0.335
2017 Batchelor E, Loewer A. Recent progress and open challenges in modeling p53 dynamics in single cells. Current Opinion in Systems Biology. 3: 54-59. PMID 29062976 DOI: 10.1016/J.Coisb.2017.04.007  0.535
2017 Yuen G, Khan FJ, Gao S, Stommel JM, Batchelor E, Wu X, Luo J. CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level. Nucleic Acids Research. PMID 29036671 DOI: 10.1093/Nar/Gkx843  0.311
2017 Porter JR, Fisher BE, Baranello L, Liu JC, Kambach DM, Nie Z, Koh WS, Luo J, Stommel JM, Levens D, Batchelor E. Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response. Molecular Cell. PMID 28867293 DOI: 10.1016/J.Molcel.2017.07.028  0.466
2017 Kieffer-Kwon KR, Nimura K, Rao SSP, Xu J, Jung S, Pekowska A, Dose M, Stevens E, Mathe E, Dong P, Huang SC, Ricci MA, Baranello L, Zheng Y, Ardori FT, ... ... Batchelor E, et al. Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation. Molecular Cell. PMID 28803781 DOI: 10.1016/J.Molcel.2017.07.013  0.337
2017 Harton MD, Batchelor E. Determining the limitations and benefits of noise in gene regulation and signal transduction through single cell, microscopy-based analysis. Journal of Molecular Biology. PMID 28288800 DOI: 10.1016/J.Jmb.2017.03.007  0.356
2017 Porter JR, Telford WG, Batchelor E. Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards. Journal of Visualized Experiments : Jove. PMID 28287544 DOI: 10.3791/55219  0.349
2017 Kambach DM, Halim AS, Cauer AG, Sun Q, Tristan CA, Celiku O, Kesarwala AH, Shankavaram U, Batchelor E, Stommel JM. Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma. Oncotarget. PMID 28118603 DOI: 10.18632/Oncotarget.14740  0.352
2016 Porter JR, Fisher BE, Batchelor E. p53 Pulses Diversify Target Gene Expression Dynamics in an mRNA Half-Life-Dependent Manner and Delineate Co-regulated Target Gene Subnetworks. Cell Systems. 2: 272-82. PMID 27135539 DOI: 10.1016/J.Cels.2016.03.006  0.488
2016 Zhou W, Chung YJ, Parrilla Castellar ER, Zheng Y, Chung HJ, Bandle R, Liu J, Tessarollo L, Batchelor E, Aplan PD, Levens D. Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing MYC Expression Levels. The American Journal of Pathology. PMID 26774856 DOI: 10.1016/J.Ajpath.2015.10.028  0.316
2015 Porter JR, Batchelor E. Using computational modeling and experimental synthetic perturbations to probe biological circuits. Methods in Molecular Biology (Clifton, N.J.). 1244: 259-76. PMID 25487101 DOI: 10.1007/978-1-4939-1878-2_12  0.345
2015 Porter JR, Fisher BE, Batchelor E. P53 Pulses Diversify Target Gene Expression Dynamics in an mRNA Half-Life-Dependent Manner and Delineate Co-regulated Target Gene Subnetworks Cell Systems. DOI: 10.1016/j.cels.2016.03.006  0.406
2013 Moody AD, Batchelor E. Promoter decoding of transcription factor dynamics. Molecular Systems Biology. 9: 703. PMID 24189398 DOI: 10.1038/Msb.2013.63  0.405
2013 Batchelor E, Kann MG, Przytycka TM, Raphael BJ, Wojtowicz D. Modeling cell heterogeneity: from single-cell variations to mixed cells. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 445-50. PMID 23424148  0.32
2012 Purvis JE, Karhohs KW, Mock C, Batchelor E, Loewer A, Lahav G. p53 dynamics control cell fate. Science (New York, N.Y.). 336: 1440-4. PMID 22700930 DOI: 10.1126/Science.1218351  0.738
2011 Batchelor E, Lahav G. Suppressing variation in synthetic circuits. Molecular Systems Biology. 7: 520. PMID 21811231 DOI: 10.1038/Msb.2011.53  0.65
2011 Batchelor E, Loewer A, Mock C, Lahav G. Stimulus-dependent dynamics of p53 in single cells. Molecular Systems Biology. 7: 488. PMID 21556066 DOI: 10.1038/Msb.2011.20  0.718
2010 Toettcher JE, Mock C, Batchelor E, Loewer A, Lahav G. A synthetic-natural hybrid oscillator in human cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 17047-52. PMID 20837528 DOI: 10.1073/Pnas.1005615107  0.708
2010 Geva-Zatorsky N, Dekel E, Batchelor E, Lahav G, Alon U. Fourier analysis and systems identification of the p53 feedback loop. Proceedings of the National Academy of Sciences of the United States of America. 107: 13550-5. PMID 20622152 DOI: 10.1073/Pnas.1001107107  0.716
2010 Loewer A, Batchelor E, Gaglia G, Lahav G. Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells. Cell. 142: 89-100. PMID 20598361 DOI: 10.1016/J.Cell.2010.05.031  0.705
2009 Batchelor E, Loewer A, Lahav G. The ups and downs of p53: understanding protein dynamics in single cells. Nature Reviews. Cancer. 9: 371-7. PMID 19360021 DOI: 10.1038/Nrc2604  0.695
2008 Batchelor E, Mock CS, Bhan I, Loewer A, Lahav G. Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage. Molecular Cell. 30: 277-89. PMID 18471974 DOI: 10.1016/J.Molcel.2008.03.016  0.691
2006 Batchelor E, Goulian M. Imaging OmpR localization in Escherichia coli Molecular Microbiology. 59: 1767-1778. PMID 16553882 DOI: 10.1111/J.1365-2958.2006.05048.X  0.569
2005 Batchelor E, Walthers D, Kenney LJ, Goulian M. The Escherichia coli CpxA-CpxR envelope stress response system regulates expression of the porins OmpF and OmpC Journal of Bacteriology. 187: 5723-5731. PMID 16077119 DOI: 10.1128/Jb.187.16.5723-5731.2005  0.58
2004 Batchelor E, Silhavy TJ, Goulian M. Continuous control in bacterial regulatory circuits Journal of Bacteriology. 186: 7618-7625. PMID 15516575 DOI: 10.1128/Jb.186.22.7618-7625.2004  0.582
2003 Batchelor E, Goulian M. Robustness and the cycle of phosphorylation and dephosphorylation in a two-component regulatory system Proceedings of the National Academy of Sciences of the United States of America. 100: 691-696. PMID 12522261 DOI: 10.1073/Pnas.0234782100  0.581
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