Year |
Citation |
Score |
2021 |
Johansson PA, Brattås PL, Douse CH, Hsieh P, Adami A, Pontis J, Grassi D, Garza R, Sozzi E, Cataldo R, Jönsson ME, Atacho DAM, Pircs K, Eren F, Sharma Y, ... ... Trono D, et al. A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development. Cell Stem Cell. PMID 34624206 DOI: 10.1016/j.stem.2021.09.008 |
0.725 |
|
2020 |
Turelli P, Playfoot C, Grun D, Raclot C, Pontis J, Coudray A, Thorball C, Duc J, Pankevich EV, Deplancke B, Busskamp V, Trono D. Primate-restricted KRAB zinc finger proteins and target retrotransposons control gene expression in human neurons. Science Advances. 6: eaba3200. PMID 32923624 DOI: 10.1126/Sciadv.Aba3200 |
0.384 |
|
2020 |
Wolf G, de Iaco A, Sun MA, Bruno M, Tinkham M, Hoang D, Mitra A, Ralls S, Trono D, Macfarlan TS. KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage. Elife. 9. PMID 32479262 DOI: 10.7554/Elife.56337 |
0.344 |
|
2020 |
Kauzlaric A, Jang SM, Morchikh M, Cassano M, Planet E, Benkirane M, Trono D. KAP1 targets actively transcribed genomic loci to exert pleomorphic effects on RNA polymerase II activity. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 375: 20190334. PMID 32068487 DOI: 10.1098/Rstb.2019.0334 |
0.408 |
|
2020 |
Wolf G, Iaco Ad, Sun M, Bruno M, Tinkham M, Hoang D, Mitra A, Ralls S, Trono D, Macfarlan TS. Author response: KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage Elife. DOI: 10.7554/Elife.56337.Sa2 |
0.312 |
|
2019 |
De Iaco A, Verp S, Offner S, Grun D, Trono D. DUX is a non-essential synchronizer of zygotic genome activation. Development (Cambridge, England). PMID 31806660 DOI: 10.1242/Dev.177725 |
0.383 |
|
2019 |
Helleboid PY, Heusel M, Duc J, Piot C, Thorball CW, Coluccio A, Pontis J, Imbeault M, Turelli P, Aebersold R, Trono D. The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification. The Embo Journal. e101220. PMID 31403225 DOI: 10.15252/Embj.2018101220 |
0.367 |
|
2019 |
Sun Y, Keown JR, Black MM, Raclot C, Demarais N, Trono D, Turelli P, Goldstone DC. A Dissection of Oligomerisation by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family. Journal of Molecular Biology. PMID 31078555 DOI: 10.1016/J.Jmb.2019.05.002 |
0.333 |
|
2019 |
Pontis J, Planet E, Offner S, Turelli P, Duc J, Coudray A, Theunissen TW, Jaenisch R, Trono D. Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs. Cell Stem Cell. PMID 31006620 DOI: 10.1016/J.Stem.2019.03.012 |
0.4 |
|
2019 |
Chen W, Schwalie PC, Pankevich EV, Gubelmann C, Raghav SK, Dainese R, Cassano M, Imbeault M, Jang SM, Russeil J, Delessa T, Duc J, Trono D, Wolfrum C, Deplancke B. ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer. Nature Communications. 10: 1809. PMID 31000713 DOI: 10.1038/S41467-019-09803-9 |
0.395 |
|
2019 |
De Iaco A, Coudray A, Duc J, Trono D. DPPA2 and DPPA4 are necessary to establish a 2C-like state in mouse embryonic stem cells. Embo Reports. PMID 30948459 DOI: 10.15252/Embr.201847382 |
0.409 |
|
2019 |
Takahashi N, Coluccio A, Thorball CW, Planet E, Shi H, Offner S, Turelli P, Imbeault M, Ferguson-Smith AC, Trono D. ZNF445 is a primary regulator of genomic imprinting. Genes & Development. 33: 49-54. PMID 30602440 DOI: 10.1101/Gad.320069.118 |
0.368 |
|
2018 |
Unzu C, Planet E, Brandenberg N, Fusil F, Cassano M, Perez-Vargas J, Friedli M, Cosset FL, Lutolf MP, Wildhaber BE, Trono D. Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes. Hepatology (Baltimore, Md.). PMID 30549291 DOI: 10.1002/Hep.30425 |
0.347 |
|
2018 |
Kawano K, Doucet AJ, Ueno M, Kariya R, An W, Marzetta F, Kuroki M, Turelli P, Sukegawa S, Okada S, Strebel K, Trono D, Ariumi Y. HIV-1 Vpr and p21 restrict LINE-1 mobility. Nucleic Acids Research. PMID 30085096 DOI: 10.1093/Nar/Gky688 |
0.346 |
|
2018 |
Jang SM, Kauzlaric A, Quivy JP, Pontis J, Rauwel B, Coluccio A, Offner S, Duc J, Turelli P, Almouzni G, Trono D. KAP1 facilitates reinstatement of heterochromatin after DNA replication. Nucleic Acids Research. PMID 29955894 DOI: 10.1093/Nar/Gky580 |
0.328 |
|
2018 |
Coluccio A, Ecco G, Duc J, Offner S, Turelli P, Trono D. Individual retrotransposon integrants are differentially controlled by KZFP/KAP1-dependent histone methylation, DNA methylation and TET-mediated hydroxymethylation in naïve embryonic stem cells. Epigenetics & Chromatin. 11: 7. PMID 29482634 DOI: 10.1186/S13072-018-0177-1 |
0.33 |
|
2017 |
Ecco G, Imbeault M, Trono D. KRAB zinc finger proteins. Development (Cambridge, England). 144: 2719-2729. PMID 28765213 DOI: 10.1242/Dev.132605 |
0.348 |
|
2017 |
Trono D. A KRABsody for Embryo-Placental Development. Developmental Cell. 41: 578-580. PMID 28633014 DOI: 10.1016/J.Devcel.2017.06.005 |
0.337 |
|
2017 |
De Iaco A, Planet E, Coluccio A, Verp S, Duc J, Trono D. DUX-family transcription factors regulate zygotic genome activation in placental mammals. Nature Genetics. PMID 28459456 DOI: 10.1038/Ng.3858 |
0.414 |
|
2017 |
Kauzlaric A, Ecco G, Cassano M, Duc J, Imbeault M, Trono D. The mouse genome displays highly dynamic populations of KRAB-zinc finger protein genes and related genetic units. Plos One. 12: e0173746. PMID 28334004 DOI: 10.1371/Journal.Pone.0173746 |
0.379 |
|
2017 |
Imbeault M, Helleboid PY, Trono D. KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks. Nature. PMID 28273063 DOI: 10.1038/Nature21683 |
0.411 |
|
2017 |
Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nature Methods. PMID 28092692 DOI: 10.1038/Nmeth.4143 |
0.306 |
|
2016 |
Naldini L, Trono D, Verma IM. Lentiviral vectors, two decades later. Science (New York, N.Y.). 353: 1101-2. PMID 27609877 DOI: 10.1126/Science.Aah6192 |
0.445 |
|
2016 |
Theunissen TW, Friedli M, He Y, Planet E, O'Neil RC, Markoulaki S, Pontis J, Wang H, Iouranova A, Imbeault M, Duc J, Cohen MA, Wert KJ, Castanon R, Zhang Z, ... ... Trono D, et al. Molecular Criteria for Defining the Naive Human Pluripotent State. Cell Stem Cell. PMID 27424783 DOI: 10.1016/J.Stem.2016.06.011 |
0.357 |
|
2016 |
Ecco G, Cassano M, Kauzlaric A, Duc J, Coluccio A, Offner S, Imbeault M, Rowe HM, Turelli P, Trono D. Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues. Developmental Cell. 36: 611-23. PMID 27003935 DOI: 10.1016/J.Devcel.2016.02.024 |
0.423 |
|
2016 |
Ecco G, Rowe HM, Trono D. A Large-Scale Functional Screen to Identify Epigenetic Repressors of Retrotransposon Expression. Methods in Molecular Biology (Clifton, N.J.). 1400: 403-17. PMID 26895067 DOI: 10.1007/978-1-4939-3372-3_25 |
0.366 |
|
2016 |
Trono D. Transposable Elements, Polydactyl Proteins, and the Genesis of Human-Specific Transcription Networks. Cold Spring Harbor Symposia On Quantitative Biology. PMID 26763983 DOI: 10.1101/Sqb.2015.80.027573 |
0.387 |
|
2015 |
Kapopoulou A, Mathew L, Wong A, Trono D, Jensen JD. The evolution of gene expression and binding specificity of the largest transcription factor family in primates. Evolution; International Journal of Organic Evolution. PMID 26593440 DOI: 10.1111/Evo.12819 |
0.379 |
|
2015 |
Castro-Diaz N, Friedli M, Trono D. Drawing a fine line on endogenous retroelement activity. Mobile Genetic Elements. 5: 1-6. PMID 26442176 DOI: 10.1080/2159256X.2015.1006109 |
0.374 |
|
2015 |
Friedli M, Trono D. The Developmental Control of Transposable Elements and the Evolution of Higher Species. Annual Review of Cell and Developmental Biology. 31: 429-51. PMID 26393776 DOI: 10.1146/Annurev-Cellbio-100814-125514 |
0.391 |
|
2015 |
Dietrich JE, Panavaite L, Gunther S, Wennekamp S, Groner AC, Pigge A, Salvenmoser S, Trono D, Hufnagel L, Hiiragi T. Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages. Embo Reports. 16: 1005-21. PMID 26142281 DOI: 10.15252/Embr.201540162 |
0.392 |
|
2015 |
Rauwel B, Jang SM, Cassano M, Kapopoulou A, Barde I, Trono D. Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch. Elife. 4. PMID 25846574 DOI: 10.7554/Elife.06068 |
0.355 |
|
2015 |
Singh K, Cassano M, Planet E, Sebastian S, Jang SM, Sohi G, Faralli H, Choi J, Youn HD, Dilworth FJ, Trono D. A KAP1 phosphorylation switch controls MyoD function during skeletal muscle differentiation. Genes & Development. 29: 513-25. PMID 25737281 DOI: 10.1101/Gad.254532.114 |
0.35 |
|
2015 |
Fasching L, Kapopoulou A, Sachdeva R, Petri R, Jönsson ME, Männe C, Turelli P, Jern P, Cammas F, Trono D, Jakobsson J. TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells. Cell Reports. 10: 20-8. PMID 25543143 DOI: 10.1016/J.Celrep.2014.12.004 |
0.744 |
|
2014 |
Gubelmann C, Schwalie PC, Raghav SK, Röder E, Delessa T, Kiehlmann E, Waszak SM, Corsinotti A, Udin G, Holcombe W, Rudofsky G, Trono D, Wolfrum C, Deplancke B. Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network. Elife. 3: e03346. PMID 25163748 DOI: 10.7554/Elife.03346 |
0.394 |
|
2014 |
Castro-Diaz N, Ecco G, Coluccio A, Kapopoulou A, Yazdanpanah B, Friedli M, Duc J, Jang SM, Turelli P, Trono D. Evolutionally dynamic L1 regulation in embryonic stem cells. Genes & Development. 28: 1397-409. PMID 24939876 DOI: 10.1101/Gad.241661.114 |
0.365 |
|
2014 |
Turelli P, Castro-Diaz N, Marzetta F, Kapopoulou A, Raclot C, Duc J, Tieng V, Quenneville S, Trono D. Interplay of TRIM28 and DNA methylation in controlling human endogenous retroelements. Genome Research. 24: 1260-70. PMID 24879559 DOI: 10.1101/Gr.172833.114 |
0.389 |
|
2014 |
Friedli M, Turelli P, Kapopoulou A, Rauwel B, Castro-Díaz N, Rowe HM, Ecco G, Unzu C, Planet E, Lombardo A, Mangeat B, Wildhaber BE, Naldini L, Trono D. Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency. Genome Research. 24: 1251-9. PMID 24879558 DOI: 10.1101/Gr.172809.114 |
0.409 |
|
2014 |
Chiriaco M, Farinelli G, Capo V, Zonari E, Scaramuzza S, Di Matteo G, Sergi LS, Migliavacca M, Hernandez RJ, Bombelli F, Giorda E, Kajaste-Rudnitski A, Trono D, Grez M, Rossi P, et al. Dual-regulated lentiviral vector for gene therapy of X-linked chronic granulomatosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1472-83. PMID 24869932 DOI: 10.1038/Mt.2014.87 |
0.395 |
|
2014 |
Barde I, Rauwel B, Marin-Florez RM, Corsinotti A, Laurenti E, Verp S, Offner S, Marquis J, Kapopoulou A, Vanicek J, Trono D. [A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy]. MéDecine Sciences : M/S. 30: 12-5. PMID 24472449 DOI: 10.1051/Medsci/20143001003 |
0.363 |
|
2014 |
Gubelmann C, Schwalie PC, Raghav SK, Röder E, Delessa T, Kiehlmann E, Waszak SM, Corsinotti A, Udin G, Holcombe W, Rudofsky G, Trono D, Wolfrum C, Deplancke B. Author response: Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network Elife. DOI: 10.7554/Elife.03346.020 |
0.305 |
|
2013 |
Jaguva Vasudevan AA, Perkovic M, Bulliard Y, Cichutek K, Trono D, Häussinger D, Münk C. Prototype foamy virus Bet impairs the dimerization and cytosolic solubility of human APOBEC3G. Journal of Virology. 87: 9030-40. PMID 23760237 DOI: 10.1128/Jvi.03385-12 |
0.33 |
|
2013 |
Andrey G, Montavon T, Mascrez B, Gonzalez F, Noordermeer D, Leleu M, Trono D, Spitz F, Duboule D. A switch between topological domains underlies HoxD genes collinearity in mouse limbs. Science (New York, N.Y.). 340: 1234167. PMID 23744951 DOI: 10.1126/Science.1234167 |
0.325 |
|
2013 |
Barde I, Rauwel B, Marin-Florez RM, Corsinotti A, Laurenti E, Verp S, Offner S, Marquis J, Kapopoulou A, Vanicek J, Trono D. A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy. Science (New York, N.Y.). 340: 350-3. PMID 23493425 DOI: 10.1126/Science.1232398 |
0.339 |
|
2013 |
Corsinotti A, Kapopoulou A, Gubelmann C, Imbeault M, Santoni de Sio FR, Rowe HM, Mouscaz Y, Deplancke B, Trono D. Global and stage specific patterns of Krüppel-associated-box zinc finger protein gene expression in murine early embryonic cells. Plos One. 8: e56721. PMID 23451074 DOI: 10.1371/Journal.Pone.0056721 |
0.443 |
|
2013 |
Rowe HM, Friedli M, Offner S, Verp S, Mesnard D, Marquis J, Aktas T, Trono D. De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET. Development (Cambridge, England). 140: 519-29. PMID 23293284 DOI: 10.1242/Dev.087585 |
0.341 |
|
2013 |
Rowe HM, Kapopoulou A, Corsinotti A, Fasching L, Macfarlan TS, Tarabay Y, Viville S, Jakobsson J, Pfaff SL, Trono D. TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells. Genome Research. 23: 452-61. PMID 23233547 DOI: 10.1101/Gr.147678.112 |
0.627 |
|
2012 |
Quenneville S, Turelli P, Bojkowska K, Raclot C, Offner S, Kapopoulou A, Trono D. The KRAB-ZFP/KAP1 system contributes to the early embryonic establishment of site-specific DNA methylation patterns maintained during development. Cell Reports. 2: 766-73. PMID 23041315 DOI: 10.1016/J.Celrep.2012.08.043 |
0.312 |
|
2012 |
Santoni de Sio FR, Barde I, Offner S, Kapopoulou A, Corsinotti A, Bojkowska K, Genolet R, Thomas JH, Luescher IF, Pinschewer D, Harris N, Trono D. KAP1 regulates gene networks controlling T-cell development and responsiveness. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 4561-75. PMID 22872677 DOI: 10.1096/Fj.12-206177 |
0.398 |
|
2012 |
Åkerblom M, Sachdeva R, Barde I, Verp S, Gentner B, Trono D, Jakobsson J. MicroRNA-124 is a subventricular zone neuronal fate determinant. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8879-89. PMID 22745489 DOI: 10.1523/Jneurosci.0558-12.2012 |
0.526 |
|
2012 |
Macfarlan TS, Gifford WD, Driscoll S, Lettieri K, Rowe HM, Bonanomi D, Firth A, Singer O, Trono D, Pfaff SL. Embryonic stem cell potency fluctuates with endogenous retrovirus activity. Nature. 487: 57-63. PMID 22722858 DOI: 10.1038/Nature11244 |
0.379 |
|
2012 |
Bojkowska K, Aloisio F, Cassano M, Kapopoulou A, Santoni de Sio F, Zangger N, Offner S, Cartoni C, Thomas C, Quenneville S, Johnsson K, Trono D. Liver-specific ablation of Krüppel-associated box-associated protein 1 in mice leads to male-predominant hepatosteatosis and development of liver adenoma. Hepatology (Baltimore, Md.). 56: 1279-90. PMID 22684873 DOI: 10.1002/Hep.25767 |
0.327 |
|
2012 |
Groner AC, Tschopp P, Challet L, Dietrich JE, Verp S, Offner S, Barde I, Rodriguez I, Hiiragi T, Trono D. The Krüppel-associated box repressor domain can induce reversible heterochromatization of a mouse locus in vivo. The Journal of Biological Chemistry. 287: 25361-9. PMID 22605343 DOI: 10.1074/Jbc.M112.350884 |
0.409 |
|
2012 |
Trono D. Gene therapy: too much splice can spoil the dish. The Journal of Clinical Investigation. 122: 1600-2. PMID 22523063 DOI: 10.1172/Jci63066 |
0.348 |
|
2012 |
Santoni de Sio FR, Massacand J, Barde I, Offner S, Corsinotti A, Kapopoulou A, Bojkowska K, Dagklis A, Fernandez M, Ghia P, Thomas JH, Pinschewer D, Harris N, Trono D. KAP1 regulates gene networks controlling mouse B-lymphoid cell differentiation and function. Blood. 119: 4675-85. PMID 22452978 DOI: 10.1182/Blood-2011-12-401117 |
0.397 |
|
2012 |
Frecha C, Costa C, Nègre D, Amirache F, Trono D, Rio P, Bueren J, Cosset FL, Verhoeyen E. A novel lentiviral vector targets gene transfer into human hematopoietic stem cells in marrow from patients with bone marrow failure syndrome and in vivo in humanized mice. Blood. 119: 1139-50. PMID 22117040 DOI: 10.1182/Blood-2011-04-346619 |
0.396 |
|
2011 |
Barde I, Verp S, Offner S, Trono D. Lentiviral Vector Mediated Transgenesis. Current Protocols in Mouse Biology. 1: 169-84. PMID 26068991 DOI: 10.1002/9780470942390.Mo100169 |
0.404 |
|
2011 |
Quenneville S, Verde G, Corsinotti A, Kapopoulou A, Jakobsson J, Offner S, Baglivo I, Pedone PV, Grimaldi G, Riccio A, Trono D. In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions. Molecular Cell. 44: 361-72. PMID 22055183 DOI: 10.1016/J.Molcel.2011.08.032 |
0.561 |
|
2011 |
Meylan S, Groner AC, Ambrosini G, Malani N, Quenneville S, Zangger N, Kapopoulou A, Kauzlaric A, Rougemont J, Ciuffi A, Bushman FD, Bucher P, Trono D. A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing. Bmc Genomics. 12: 378. PMID 21791101 DOI: 10.1186/1471-2164-12-378 |
0.402 |
|
2011 |
Barde I, Laurenti E, Verp S, Wiznerowicz M, Offner S, Viornery A, Galy A, Trumpp A, Trono D. Lineage-and stage-restricted lentiviral vectors for the gene therapy of chronic granulomatous disease Gene Therapy. 18: 1087-1097. PMID 21544095 DOI: 10.1038/Gt.2011.65 |
0.432 |
|
2011 |
Robyr D, Friedli M, Gehrig C, Arcangeli M, Marin M, Guipponi M, Farinelli L, Barde I, Verp S, Trono D, Antonarakis SE. Chromosome conformation capture uncovers potential genome-wide interactions between human conserved non-coding sequences. Plos One. 6: e17634. PMID 21408183 DOI: 10.1371/Journal.Pone.0017634 |
0.325 |
|
2011 |
Trono D, Marzetta F. Profaning the ultimate sanctuary: HIV latency in hematopoietic stem cells. Cell Host & Microbe. 9: 170-2. PMID 21402354 DOI: 10.1016/J.Chom.2011.03.001 |
0.359 |
|
2011 |
Pasi CE, Dereli-Öz A, Negrini S, Friedli M, Fragola G, Lombardo A, Van Houwe G, Naldini L, Casola S, Testa G, Trono D, Pelicci PG, Halazonetis TD. Genomic instability in induced stem cells. Cell Death and Differentiation. 18: 745-53. PMID 21311564 DOI: 10.1038/Cdd.2011.9 |
0.382 |
|
2011 |
Rowe HM, Trono D. Dynamic control of endogenous retroviruses during development. Virology. 411: 273-87. PMID 21251689 DOI: 10.1016/J.Virol.2010.12.007 |
0.332 |
|
2011 |
Maillard PV, Zoete V, Michielin O, Trono D. Homology-based identification of capsid determinants that protect HIV1 from human TRIM5α restriction. The Journal of Biological Chemistry. 286: 8128-40. PMID 21169362 DOI: 10.1074/Jbc.M110.187609 |
0.367 |
|
2011 |
Bulliard Y, Narvaiza I, Bertero A, Peddi S, Röhrig UF, Ortiz M, Zoete V, Castro-DÃaz N, Turelli P, Telenti A, Michielin O, Weitzman MD, Trono D. Structure-function analyses point to a polynucleotide-accommodating groove essential for APOBEC3A restriction activities. Journal of Virology. 85: 1765-76. PMID 21123384 DOI: 10.1128/Jvi.01651-10 |
0.315 |
|
2010 |
Friedli M, Barde I, Arcangeli M, Verp S, Quazzola A, Zakany J, Lin-Marq N, Robyr D, Attanasio C, Spitz F, Duboule D, Trono D, Antonarakis SE. A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the Olig1 and Olig2 locus. Plos One. 5: e15741. PMID 21206754 DOI: 10.1371/Journal.Pone.0015741 |
0.376 |
|
2010 |
Barde I, Salmon P, Trono D. Production and titration of lentiviral vectors. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.21. PMID 20938923 DOI: 10.1002/0471142301.Ns0421S53 |
0.375 |
|
2010 |
Laurenti E, Barde I, Verp S, Offner S, Wilson A, Quenneville S, Wiznerowicz M, Macdonald HR, Trono D, Trumpp A. Inducible gene and shRNA expression in resident hematopoietic stem cells in vivo. Stem Cells (Dayton, Ohio). 28: 1390-8. PMID 20641037 DOI: 10.1002/Stem.460 |
0.395 |
|
2010 |
Trono D, Van Lint C, Rouzioux C, Verdin E, Barré-Sinoussi F, Chun TW, Chomont N. HIV persistence and the prospect of long-term drug-free remissions for hiv-infected individuals Science. 329: 174-180. PMID 20616270 DOI: 10.1126/Science.1191047 |
0.323 |
|
2010 |
Groner AC, Meylan S, Ciuffi A, Zangger N, Ambrosini G, Dénervaud N, Bucher P, Trono D. KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading. Plos Genetics. 6: e1000869. PMID 20221260 DOI: 10.1371/Journal.Pgen.1000869 |
0.404 |
|
2010 |
Rowe HM, Jakobsson J, Mesnard D, Rougemont J, Reynard S, Aktas T, Maillard PV, Layard-Liesching H, Verp S, Marquis J, Spitz F, Constam DB, Trono D. KAP1 controls endogenous retroviruses in embryonic stem cells. Nature. 463: 237-40. PMID 20075919 DOI: 10.1038/Nature08674 |
0.628 |
|
2009 |
Meylan S, Trono D. Innate immunity against retroviral pathogens: from an ambiguous genetic self to novel therapeutic approaches. Swiss Medical Weekly. 139: 706-11. PMID 20047133 DOI: 10.4414/Smw.2009.12515 |
0.347 |
|
2009 |
Bulliard Y, Turelli P, Röhrig UF, Zoete V, Mangeat B, Michielin O, Trono D. Functional analysis and structural modeling of human APOBEC3G reveal the role of evolutionarily conserved elements in the inhibition of human immunodeficiency virus type 1 infection and Alu transposition. Journal of Virology. 83: 12611-21. PMID 19776130 DOI: 10.1128/Jvi.01491-09 |
0.37 |
|
2009 |
Santoni de Sio FR, Trono D. APOBEC3G-depleted resting CD4+ T cells remain refractory to HIV1 infection. Plos One. 4: e6571. PMID 19668336 DOI: 10.1371/Journal.Pone.0006571 |
0.348 |
|
2009 |
Menzel O, Birraux J, Wildhaber BE, Jond C, Lasne F, Habre W, Trono D, Nguyen TH, Chardot C. Biosafety in ex vivo gene therapy and conditional ablation of lentivirally transduced hepatocytes in nonhuman primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1754-60. PMID 19568222 DOI: 10.1038/Mt.2009.143 |
0.331 |
|
2009 |
Barde I, Laurenti E, Verp S, Groner AC, Towne C, Padrun V, Aebischer P, Trumpp A, Trono D. Regulation of episomal gene expression by KRAB/KAP1-mediated histone modifications. Journal of Virology. 83: 5574-80. PMID 19279087 DOI: 10.1128/Jvi.00001-09 |
0.399 |
|
2009 |
Meyer K, Marquis J, Trüb J, Nlend Nlend R, Verp S, Ruepp MD, Imboden H, Barde I, Trono D, Schümperli D. Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation. Human Molecular Genetics. 18: 546-55. PMID 19010792 DOI: 10.1093/Hmg/Ddn382 |
0.333 |
|
2008 |
Jakobsson J, Cordero MI, Bisaz R, Groner AC, Busskamp V, Bensadoun JC, Cammas F, Losson R, Mansuy IM, Sandi C, Trono D. KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress. Neuron. 60: 818-31. PMID 19081377 DOI: 10.1016/J.Neuron.2008.09.036 |
0.593 |
|
2008 |
Asparuhova MB, Barde I, Trono D, Schranz K, Schümperli D. Development and characterization of a triple combination gene therapy vector inhibiting HIV-1 multiplication. The Journal of Gene Medicine. 10: 1059-70. PMID 18642399 DOI: 10.1002/Jgm.1238 |
0.354 |
|
2008 |
Bach D, Peddi S, Mangeat B, Lakkaraju A, Strub K, Trono D. Characterization of APOBEC3G binding to 7SL RNA. Retrovirology. 5: 54. PMID 18597676 DOI: 10.1186/1742-4690-5-54 |
0.327 |
|
2008 |
Diaz-Griffero F, Perron M, McGee-Estrada K, Hanna R, Maillard PV, Trono D, Sodroski J. A human TRIM5alpha B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus. Virology. 378: 233-42. PMID 18586294 DOI: 10.1016/J.Virol.2008.05.008 |
0.307 |
|
2008 |
Sauvain MO, Dorr AP, Stevenson B, Quazzola A, Naef F, Wiznerowicz M, Schütz F, Jongeneel V, Duboule D, Spitz F, Trono D. Genotypic features of lentivirus transgenic mice. Journal of Virology. 82: 7111-9. PMID 18463153 DOI: 10.1128/Jvi.00623-08 |
0.363 |
|
2007 |
Salmon P, Trono D. Production and titration of lentiviral vectors. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 12.10. PMID 18428406 DOI: 10.1002/0471142905.Hg1210S54 |
0.38 |
|
2007 |
Maillard PV, Reynard S, Serhan F, Turelli P, Trono D. Interfering residues narrow the spectrum of MLV restriction by human TRIM5alpha. Plos Pathogens. 3: e200. PMID 18166079 DOI: 10.1371/Journal.Ppat.0030200 |
0.339 |
|
2007 |
Wiznerowicz M, Jakobsson J, Szulc J, Liao S, Quazzola A, Beermann F, Aebischer P, Trono D. The Kruppel-associated box repressor domain can trigger de novo promoter methylation during mouse early embryogenesis. The Journal of Biological Chemistry. 282: 34535-41. PMID 17893143 DOI: 10.1074/Jbc.M705898200 |
0.618 |
|
2007 |
Dayer AG, Jenny B, Sauvain MO, Potter G, Salmon P, Zgraggen E, Kanemitsu M, Gascon E, Sizonenko S, Trono D, Kiss JZ. Expression of FGF-2 in neural progenitor cells enhances their potential for cellular brain repair in the rodent cortex. Brain : a Journal of Neurology. 130: 2962-76. PMID 17728358 DOI: 10.1093/Brain/Awm200 |
0.327 |
|
2007 |
Malashicheva A, Kanzler B, Tolkunova E, Trono D, Tomilin A. Lentivirus as a tool for lineage-specific gene manipulations. Genesis (New York, N.Y. : 2000). 45: 456-9. PMID 17607693 DOI: 10.1002/Dvg.20313 |
0.353 |
|
2007 |
Asparuhova MB, Marti G, Liu S, Serhan F, Trono D, Schümperli D. Inhibition of HIV-1 multiplication by a modified U7 snRNA inducing Tat and Rev exon skipping. The Journal of Gene Medicine. 9: 323-34. PMID 17474072 DOI: 10.1002/Jgm.1027 |
0.377 |
|
2007 |
Fodor A, Harel C, Fodor L, Armoni M, Salmon P, Trono D, Karnieli E. Adult rat liver cells transdifferentiated with lentiviral IPF1 vectors reverse diabetes in mice: An ex vivo gene therapy approach Diabetologia. 50: 121-130. PMID 17131142 DOI: 10.1007/S00125-006-0509-8 |
0.361 |
|
2006 |
Themis M, Waddington SN, Schmidt M, von Kalle C, Wang Y, Al-Allaf F, Gregory LG, Nivsarkar M, Themis M, Holder MV, Buckley SM, Dighe N, Ruthe AT, Mistry A, Bigger B, ... ... Trono D, et al. Corrigendum to "Oncogenesis Following Delivery of a Nonprimate Lentiviral Gene Therapy Vector to Fetal and Neonatal Mice". Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 830. PMID 28189020 DOI: 10.1016/J.Ymthe.2005.10.003 |
0.318 |
|
2006 |
Salmon P, Trono D. Production and titration of lentiviral vectors. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.21. PMID 18428637 DOI: 10.1002/0471142301.Ns0421S37 |
0.375 |
|
2006 |
Bulliard Y, Wiznerowicz M, Barde I, Trono D. KRAB can repress lentivirus proviral transcription independently of integration site. The Journal of Biological Chemistry. 281: 35742-6. PMID 16997916 DOI: 10.1074/Jbc.M602843200 |
0.4 |
|
2006 |
Wiznerowicz M, Szulc J, Trono D. Tuning silence: conditional systems for RNA interference. Nature Methods. 3: 682-8. PMID 16929312 DOI: 10.1038/Nmeth914 |
0.341 |
|
2006 |
Ariumi Y, Serhan F, Turelli P, Telenti A, Trono D. The integrase interactor 1 (INI1) proteins facilitate Tat-mediated human immunodeficiency virus type 1 transcription. Retrovirology. 3: 47. PMID 16889668 DOI: 10.1186/1742-4690-3-47 |
0.407 |
|
2006 |
Eberhardt M, Salmon P, von Mach MA, Hengstler JG, Brulport M, Linscheid P, Seboek D, Oberholzer J, Barbero A, Martin I, Müller B, Trono D, Zulewski H. Multipotential nestin and Isl-1 positive mesenchymal stem cells isolated from human pancreatic islets. Biochemical and Biophysical Research Communications. 345: 1167-76. PMID 16713999 DOI: 10.1016/J.Bbrc.2006.05.016 |
0.367 |
|
2006 |
Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B. Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Molecular and Cellular Biology. 26: 3266-81. PMID 16581799 DOI: 10.1128/Mcb.26.8.3266-3281.2006 |
0.343 |
|
2006 |
Ariumi Y, Trono D. Ataxia-telangiectasia-mutated (ATM) protein can enhance human immunodeficiency virus type 1 replication by stimulating Rev function. Journal of Virology. 80: 2445-52. PMID 16474151 DOI: 10.1128/Jvi.80.5.2445-2452.2006 |
0.418 |
|
2006 |
Szulc J, Wiznerowicz M, Sauvain MO, Trono D, Aebischer P. A versatile tool for conditional gene expression and knockdown. Nature Methods. 3: 109-16. PMID 16432520 DOI: 10.1016/J.Ymthe.2006.08.383 |
0.422 |
|
2005 |
Nguyen TH, Khakhoulina T, Simmons A, Morel P, Trono D. A simple and highly effective method for the stable transduction of uncultured porcine hepatocytes using lentiviral vector. Cell Transplantation. 14: 489-96. PMID 16285257 DOI: 10.3727/000000005783982828 |
0.378 |
|
2005 |
Nguyen TH, Bellodi-Privato M, Aubert D, Pichard V, Myara A, Trono D, Ferry N. Therapeutic lentivirus-mediated neonatal in vivo gene therapy in hyperbilirubinemic Gunn rats. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 852-9. PMID 16140582 DOI: 10.1016/J.Ymthe.2005.06.482 |
0.323 |
|
2005 |
Themis M, Waddington SN, Schmidt M, von Kalle C, Wang Y, Al-Allaf F, Gregory LG, Nivsarkar M, Themis M, Holder MV, Buckley SM, Dighe N, Ruthe AT, Mistry A, Bigger B, ... ... Trono D, et al. Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 763-71. PMID 16084128 DOI: 10.1016/J.Ymthe.2005.07.358 |
0.355 |
|
2005 |
Verhoeyen E, Wiznerowicz M, Olivier D, Izac B, Trono D, Dubart-Kupperschmitt A, Cosset FL. Novel lentiviral vectors displaying "early-acting cytokines" selectively promote survival and transduction of NOD/SCID repopulating human hematopoietic stem cells. Blood. 106: 3386-95. PMID 16076865 DOI: 10.1182/Blood-2004-12-4736 |
0.392 |
|
2005 |
Kvell K, Nguyen TH, Salmon P, Glauser F, Werner-Favre C, Barnet M, Schneider P, Trono D, Zubler RH. Transduction of CpG DNA-stimulated primary human B cells with bicistronic lentivectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 892-9. PMID 16005685 DOI: 10.1016/J.Ymthe.2005.05.010 |
0.379 |
|
2005 |
Miyake K, Flygare J, Kiefer T, Utsugisawa T, Richter J, Ma Z, Wiznerowicz M, Trono D, Karlsson S. Development of cellular models for ribosomal protein S19 (RPS19)-deficient diamond-blackfan anemia using inducible expression of siRNA against RPS19. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 627-37. PMID 15771965 DOI: 10.1016/J.Ymthe.2004.12.001 |
0.426 |
|
2005 |
Ariumi Y, Turelli P, Masutani M, Trono D. DNA damage sensors ATM, ATR, DNA-PKcs, and PARP-1 are dispensable for human immunodeficiency virus type 1 integration. Journal of Virology. 79: 2973-8. PMID 15709017 DOI: 10.1128/Jvi.79.5.2973-2978.2005 |
0.378 |
|
2005 |
Wiznerowicz M, Trono D. Harnessing HIV for therapy, basic research and biotechnology. Trends in Biotechnology. 23: 42-7. PMID 15629857 DOI: 10.1016/J.Tibtech.2004.11.001 |
0.413 |
|
2005 |
Flygare J, Kiefer T, Miyake K, Utsugisawa T, Hamaguchi I, Da Costa L, Richter J, Davey EJ, Matsson H, Dahl N, Wiznerowicz M, Trono D, Karlsson S. Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia. Blood. 105: 4627-34. PMID 15626736 DOI: 10.1182/Blood-2004-08-3115 |
0.382 |
|
2005 |
Nguyen Th, Bellodi-Privato M, Aubert D, Myara A, Trono D, Ferry N. 896. Complete and Permanent Correction of Hyperbilirubinemia in Newborn Gunn Rats by Lentiviral-Mediated Gene Transfer Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.439 |
0.309 |
|
2005 |
Nguyen TH, Birraux J, Wildhaber B, Fux C, Trivin F, Myara A, Lecoultre C, Trono D. 895. Ex Vivo Gene Therapy of Metabolic Liver Disorders Using Uncultured and Lentivirally Transduced Hepatocytes Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.438 |
0.319 |
|
2004 |
Pham HM, Argañaraz ER, Groschel B, Trono D, Lama J. Lentiviral vectors interfering with virus-induced CD4 down-modulation potently block human immunodeficiency virus type 1 replication in primary lymphocytes. Journal of Virology. 78: 13072-81. PMID 15542659 DOI: 10.1128/Jvi.78.23.13072-13081.2004 |
0.36 |
|
2004 |
An P, Bleiber G, Duggal P, Nelson G, May M, Mangeat B, Alobwede I, Trono D, Vlahov D, Donfield S, Goedert JJ, Phair J, Buchbinder S, O'Brien SJ, Telenti A, et al. APOBEC3G genetic variants and their influence on the progression to AIDS. Journal of Virology. 78: 11070-6. PMID 15452227 DOI: 10.1128/Jvi.78.20.11070-11076.2004 |
0.345 |
|
2004 |
Arrighi JF, Pion M, Wiznerowicz M, Geijtenbeek TB, Garcia E, Abraham S, Leuba F, Dutoit V, Ducrey-Rundquist O, van Kooyk Y, Trono D, Piguet V. Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells. Journal of Virology. 78: 10848-55. PMID 15452205 DOI: 10.1128/Jvi.78.20.10848-10855.2004 |
0.374 |
|
2004 |
Ciuffi A, Bleiber G, Muñoz M, Martinez R, Loeuillet C, Rehr M, Fischer M, Günthard HF, Oxenius A, Meylan P, Bonhoeffer S, Trono D, Telenti A. Entry and transcription as key determinants of differences in CD4 T-cell permissiveness to human immunodeficiency virus type 1 infection. Journal of Virology. 78: 10747-54. PMID 15367641 DOI: 10.1128/Jvi.78.19.10747-10754.2004 |
0.396 |
|
2004 |
Turelli P, Vianin S, Trono D. The innate antiretroviral factor APOBEC3G does not affect human LINE-1 retrotransposition in a cell culture assay. The Journal of Biological Chemistry. 279: 43371-3. PMID 15322092 DOI: 10.1074/Jbc.C400334200 |
0.325 |
|
2004 |
Fauré J, Stalder R, Borel C, Sobo K, Piguet V, Demaurex N, Gruenberg J, Trono D. ARF1 regulates Nef-induced CD4 degradation. Current Biology : Cb. 14: 1056-64. PMID 15202998 DOI: 10.1016/J.Cub.2004.06.021 |
0.303 |
|
2004 |
Bobardt MD, Salmon P, Wang L, Esko JD, Gabuzda D, Fiala M, Trono D, Van der Schueren B, David G, Gallay PA. Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion. Journal of Virology. 78: 6567-84. PMID 15163749 DOI: 10.1128/Jvi.78.12.6567-6584.2004 |
0.357 |
|
2004 |
Turelli P, Mangeat B, Jost S, Vianin S, Trono D. Inhibition of hepatitis B virus replication by APOBEC3G. Science (New York, N.Y.). 303: 1829. PMID 15031497 DOI: 10.1126/Science.1092066 |
0.326 |
|
2004 |
Mangeat B, Turelli P, Liao S, Trono D. A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to Vif action. The Journal of Biological Chemistry. 279: 14481-3. PMID 14966139 DOI: 10.1074/Jbc.C400060200 |
0.335 |
|
2004 |
Flygare J, Kiefer T, Miyake K, Utsugisawa T, Hamaguchi I, Costa LD, Richter J, Davey EJ, Matsson H, Dahl N, Wiznerowicz M, Trono D, Karlsson S. Hematopoietic Mechanism in Diamond-Blackfan Anemia: Late Erythroid Development Is Not Affected by Ribosomal Protein S19 Deficiency. Blood. 104: 719-719. DOI: 10.1182/Blood.V104.11.719.719 |
0.396 |
|
2004 |
Miyake K, Utsugisawa T, Flygare J, Kiefer T, Richter J, Wiznerowicz M, Trono D, Karlsson S. Apoptotic Change Is a Major Reason for Defect in Early Erythroid Development in Cell Line Models for Ribosomal Protein (RP) S19 Deficient Diamond-Blackfan Anemia. Blood. 104: 2840-2840. DOI: 10.1182/Blood.V104.11.2840.2840 |
0.365 |
|
2004 |
Miyake K, Flygare J, Kiefer T, Richter J, Hamaguchi I, Wiznerowicz M, Trono D, Karlsson S. 900. Development of models for RPS19 deficient diamond-blackfan anemia using regulatable expression of siRNA against RPS19 Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.806 |
0.42 |
|
2004 |
Khakhoulina T, Nguyen TH, Fux-Cametti C, Trono D. 409. In Vivo Comparison of Liver-Specific Enhancer-Promoter Constructs in the Context of Lentiviral Vectors Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.402 |
0.397 |
|
2004 |
Nguyen TH, Birraux J, Wildhaber B, Fux-Cametti C, Coultre CL, Trono D. 170. Ex vivo gene therapy of metabolic liver disorders using uncultured and lentivirally transduced hepatocytes Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.130 |
0.351 |
|
2003 |
Cudré-Mauroux C, Occhiodoro T, König S, Salmon P, Bernheim L, Trono D. Lentivector-mediated transfer of Bmi-1 and telomerase in muscle satellite cells yields a duchenne myoblast cell line with long-term genotypic and phenotypic stability. Human Gene Therapy. 14: 1525-33. PMID 14577914 DOI: 10.1089/104303403322495034 |
0.385 |
|
2003 |
Wiznerowicz M, Trono D. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. Journal of Virology. 77: 8957-61. PMID 12885912 DOI: 10.1128/Jvi.77.16.8957-8951.2003 |
0.372 |
|
2003 |
Mangeat B, Turelli P, Caron G, Friedli M, Perrin L, Trono D. Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts Nature. 424: 99-103. PMID 12808466 DOI: 10.1038/Nature01709 |
0.417 |
|
2003 |
Trono D. Picking the right spot Science. 300: 1670-1671. PMID 12805525 DOI: 10.1126/Science.1086238 |
0.384 |
|
2003 |
Ritz-Laser B, Gauthier BR, Estreicher A, Mamin A, Brun T, Ris F, Salmon P, Halban PA, Trono D, Philippe J. Ectopic expression of the beta-cell specific transcription factor Pdx1 inhibits glucagon gene transcription Diabetologia. 46: 810-821. PMID 12783165 DOI: 10.1007/S00125-003-1115-7 |
0.419 |
|
2003 |
Kostic C, Chiodini F, Salmon P, Wiznerowicz M, Deglon N, Hornfeld D, Trono D, Aebischer P, Schorderet DF, Munier FL, Arsenijevic Y. Activity analysis of housekeeping promoters using self-inactivating lentiviral vector delivery into the mouse retina. Gene Therapy. 10: 818-21. PMID 12704422 DOI: 10.1038/Sj.Gt.3301948 |
0.362 |
|
2003 |
Caton D, Calabrese A, Mas C, Serre-Beinier V, Charollais A, Caille D, Zufferey R, Trono D, Meda P. Lentivirus-mediated transduction of connexin cDNAs shows level- and isoform-specific alterations in insulin secretion of primary pancreatic beta-cells. Journal of Cell Science. 116: 2285-94. PMID 12697840 DOI: 10.1242/Jcs.00442 |
0.32 |
|
2003 |
Peterlin BM, Trono D. Hide, shield and strike back: How HIV-infected cells avoid immune eradication Nature Reviews Immunology. 3: 97-107. PMID 12563294 DOI: 10.1038/Nri998 |
0.313 |
|
2003 |
Verhoeyen E, Dardalhon V, Ducrey-Rundquist O, Trono D, Taylor N, Cosset FL. IL-7 surface-engineered lentiviral vectors promote survival and efficient gene transfer in resting primary T lymphocytes Blood. 101: 2167-2174. PMID 12446448 DOI: 10.1182/Blood-2002-07-2224 |
0.362 |
|
2003 |
Bovia F, Salmon P, Matthes T, Kvell K, Nguyen TH, Werner-Favre C, Barnet M, Nagy M, Leuba F, Arrighi JF, Piguet V, Trono D, Zubler RH. Efficient transduction of primary human B lymphocytes and nondividing myeloma B cells with HIV-1-derived lentiviral vectors. Blood. 101: 1727-33. PMID 12406892 DOI: 10.1182/Blood-2001-12-0249 |
0.409 |
|
2003 |
Woods NB, Muessig A, Schmidt M, Flygare J, Olsson K, Salmon P, Trono D, von Kalle C, Karlsson S. Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis. Blood. 101: 1284-9. PMID 12393514 DOI: 10.1182/Blood-2002-07-2238 |
0.407 |
|
2002 |
Guyader M, Kiyokawa E, Abrami L, Turelli P, Trono D. Role for human immunodeficiency virus type 1 membrane cholesterol in viral internalization Journal of Virology. 76: 10356-10364. PMID 12239312 DOI: 10.1128/Jvi.76.20.10356-10364.2002 |
0.337 |
|
2002 |
Vilhardt F, Plastre O, Sawada M, Suzuki K, Wiznerowicz M, Kiyokawa E, Trono D, Krause KH. The HIV-1 Nef protein and phagocyte NADPH oxidase activation Journal of Biological Chemistry. 277: 42136-42143. PMID 12207012 DOI: 10.1074/Jbc.M200862200 |
0.353 |
|
2002 |
Ducrey-Rundquist O, Guyader M, Trono D. Modalities of interleukin-7-induced human immunodeficiency virus permissiveness in quiescent T lymphocytes Journal of Virology. 76: 9103-9111. PMID 12186894 DOI: 10.1128/Jvi.76.18.9103-9111.2002 |
0.345 |
|
2002 |
Nguyen TH, Oberholzer J, Birraux J, Majno P, Morel P, Trono D. Highly efficient lentiviral vector-mediated transduction of nondividing, fully reimplantable primary hepatocytes Molecular Therapy. 6: 199-209. PMID 12161186 DOI: 10.1006/Mthe.2002.0653 |
0.392 |
|
2002 |
Sandrin V, Boson B, Salmon P, Gay W, Nègre D, Le Grand R, Trono D, Cosset FL. Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates. Blood. 100: 823-32. PMID 12130492 DOI: 10.1182/Blood-2001-11-0042 |
0.316 |
|
2002 |
Fotopoulos G, Harari A, Michetti P, Trono D, Pantaleo G, Kraehenbuhl JP. Transepithelial transport of HIV-1 by M cells is receptor-mediated Proceedings of the National Academy of Sciences of the United States of America. 99: 9410-9414. PMID 12093918 DOI: 10.1073/Pnas.142586899 |
0.347 |
|
2002 |
Lundberg C, Englund U, Trono D, Björklund A, Wictorin K. Differentiation of the RN33B cell line into forebrain projection neurons after transplantation into the neonatal rat brain. Experimental Neurology. 175: 370-87. PMID 12061867 DOI: 10.1006/Exnr.2002.7888 |
0.573 |
|
2002 |
Maurice M, Verhoeyen E, Salmon P, Trono D, Russell SJ, Cosset FL. Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell-activating polypeptide Blood. 99: 2342-2350. PMID 11895766 DOI: 10.1182/Blood.V99.7.2342 |
0.433 |
|
2002 |
Salmon P, Trono D. Lentiviral vectors for the gene therapy of lympho-hematological disorders Current Topics in Microbiology and Immunology. 261: 211-227. PMID 11892249 DOI: 10.1007/978-3-642-56114-6_11 |
0.338 |
|
2001 |
Peng KW, Pham L, Ye H, Zufferey R, Trono D, Cosset FL, Russell SJ. Organ distribution of gene expression after intravenous infusion of targeted and untargeted lentiviral vectors. Gene Therapy. 8: 1456-63. PMID 11593358 DOI: 10.1038/Sj.Gt.3301552 |
0.382 |
|
2001 |
Berton M, Turelli P, Trono D, Stein CA, Allémann E, Gurny R. Inhibition of HIV-1 in cell culture by oligonucleotide-loaded nanoparticles. Pharmaceutical Research. 18: 1096-101. PMID 11587479 DOI: 10.1023/A:1010962507273 |
0.306 |
|
2001 |
Salmon P, Arrighi JF, Piguet V, Chapuis B, Zubler RH, Trono D, Kindler V. Transduction of CD34+ cells with lentiviral vectors enables the production of large quantities of transgene-expressing immature and mature dendritic cells Journal of Gene Medicine. 3: 311-320. PMID 11529660 DOI: 10.1002/1521-2254(200107/08)3:4<311::Aid-Jgm198>3.0.Co;2-B |
0.324 |
|
2001 |
Turelli P, Doucas V, Craig E, Mangeat B, Klages N, Evans R, Kalpana G, Trono D. Cytoplasmic recruitment of INI1 and PML on incoming HIV preintegration complexes: Interference with early steps of viral replication Molecular Cell. 7: 1245-1254. PMID 11430827 DOI: 10.1016/S1097-2765(01)00255-6 |
0.356 |
|
2001 |
Woods NB, Mikkola H, Nilsson E, Olsson K, Trono D, Karlsson S. Lentiviral-mediated gene transfer into haematopoietic stem cells. Journal of Internal Medicine. 249: 339-43. PMID 11298854 DOI: 10.1046/J.1365-2796.2001.00806.X |
0.38 |
|
2001 |
Piguet V, Trono D. Living in oblivion: HIV immune evasion Seminars in Immunology. 13: 51-57. PMID 11289799 DOI: 10.1006/Smim.2000.0295 |
0.358 |
|
2000 |
Englund U, Ericson C, Rosenblad C, Mandel RJ, Trono D, Wictorin K, Lundberg C. The use of a recombinant lentiviral vector for ex vivo gene transfer into the rat CNS. Neuroreport. 11: 3973-7. PMID 11192612 DOI: 10.1097/00001756-200012180-00014 |
0.605 |
|
2000 |
Mikkola H, Woods NB, Sjögren M, Helgadottir H, Hamaguchi I, Jacobsen SE, Trono D, Karlsson S. Lentivirus gene transfer in murine hematopoietic progenitor cells is compromised by a delay in proviral integration and results in transduction mosaicism and heterogeneous gene expression in progeny cells. Journal of Virology. 74: 11911-8. PMID 11090191 DOI: 10.1128/Jvi.74.24.11911-11918.2000 |
0.405 |
|
2000 |
Woods NB, Fahlman C, Mikkola H, Hamaguchi I, Olsson K, Zufferey R, Jacobsen SE, Trono D, Karlsson S. Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells. Blood. 96: 3725-33. PMID 11090053 DOI: 10.1182/Blood.V96.12.3725.H8003725_3725_3733 |
0.402 |
|
2000 |
Diaz RM, Bateman A, Emiliusen L, Fielding A, Trono D, Russell SJ, Vile RG. A lentiviral vector expressing a fusogenic glycoprotein for cancer gene therapy. Gene Therapy. 7: 1656-63. PMID 11083474 DOI: 10.1038/Sj.Gt.3301277 |
0.386 |
|
2000 |
Salmon P, Kindler V, Ducrey O, Chapuis B, Zubler RH, Trono D. High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors Blood. 96: 3392-3398. PMID 11071633 DOI: 10.1182/Blood.V96.10.3392.H8003392_3392_3398 |
0.421 |
|
2000 |
Saulnier SO, Steinhoff D, Dinauer MC, Zufferey R, Trono D, Seger RA, Hossle JP. Lentivirus-mediated gene transfer of gp91phox corrects chronic granulomatous disease (CGD) phenotype in human X-CGD cells. The Journal of Gene Medicine. 2: 317-25. PMID 11045425 DOI: 10.1002/1521-2254(200009/10)2:5<317::Aid-Jgm127>3.0.Co;2-P |
0.305 |
|
2000 |
Hamaguchi I, Woods NB, Panagopoulos I, Andersson E, Mikkola H, Fahlman C, Zufferey R, Carlsson L, Trono D, Karlsson S. Lentivirus vector gene expression during ES cell-derived hematopoietic development in vitro. Journal of Virology. 74: 10778-84. PMID 11044122 DOI: 10.1128/Jvi.74.22.10778-10784.2000 |
0.423 |
|
2000 |
Salmon P, Oberholzer J, Occhiodoro T, Morel P, Lou J, Trono D. Reversible immortalization of human primary cells by lentivector-mediated transfer of specific genes Molecular Therapy. 2: 404-414. PMID 11020357 DOI: 10.1006/Mthe.2000.0141 |
0.425 |
|
2000 |
Klages N, Zufferey R, Trono D. A stable system for the high-titer production of multiply attenuated lentiviral vectors Molecular Therapy. 2: 170-176. PMID 10947945 DOI: 10.1006/Mthe.2000.0103 |
0.451 |
|
2000 |
Bosch A, Perret E, Desmaris N, Trono D, Heard JM. Reversal of pathology in the entire brain of mucopolysaccharidosis type VII mice after lentivirus-mediated gene transfer. Human Gene Therapy. 11: 1139-50. PMID 10834616 DOI: 10.1089/10430340050015194 |
0.368 |
|
2000 |
Trono D. HIV-based vectors: getting the best out of the worst. The Journal of Gene Medicine. 2: 61-3. PMID 10765506 DOI: 10.1002/(Sici)1521-2254(200001/02)2:1<61::Aid-Jgm92>3.0.Co;2-1 |
0.306 |
|
2000 |
Piguet V, Wan L, Borel C, Mangasarian A, Demaurex N, Thomas G, Trono D. HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes Nature Cell Biology. 2: 163-167. PMID 10707087 DOI: 10.1038/35004038 |
0.363 |
|
2000 |
Trono D. Lentiviral vectors: turning a deadly foe into a therapeutic agent. Gene Therapy. 7: 20-3. PMID 10680011 DOI: 10.1038/Sj.Gt.3301105 |
0.326 |
|
2000 |
Rosenblad C, Grønborg M, Hansen C, Blom N, Meyer M, Johansen J, Dagø L, Kirik D, Patel UA, Lundberg C, Trono D, Björklund A, Johansen TE. In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin. Molecular and Cellular Neurosciences. 15: 199-214. PMID 10673327 DOI: 10.1006/Mcne.1999.0817 |
0.533 |
|
2000 |
Déglon N, Tseng JL, Bensadoun JC, Zurn AD, Arsenijevic Y, De Almeida LP, Zufferey R, Trono D, Aebischer P. Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease Human Gene Therapy. 11: 179-190. PMID 10646649 DOI: 10.1089/10430340050016256 |
0.354 |
|
2000 |
Wang JK, Kiyokawa E, Verdin E, Trono D. The Nef protein of HIV-1 associates with rafts and primes T cells for activation Proceedings of the National Academy of Sciences of the United States of America. 97: 394-399. PMID 10618429 DOI: 10.1073/Pnas.97.1.394 |
0.351 |
|
2000 |
Foti M, Cartier L, Piguet V, Lew DP, Carpentier JL, Trono D, Krause KH. The HIV Nef protein alters Ca(2+) signaling in myelomonocytic cells through SH3-mediated protein-protein interactions. The Journal of Biological Chemistry. 274: 34765-72. PMID 10574946 DOI: 10.1074/Jbc.274.49.34765 |
0.329 |
|
2000 |
Zufferey R, Trono D. Production of High‐Titer Lentiviral Vectors Current Protocols in Human Genetics. 26. DOI: 10.1002/0471142905.Hg1210S26 |
0.411 |
|
1999 |
Dupraz P, Rinsch C, Pralong WF, Rolland E, Zufferey R, Trono D, Thorens B. Lentivirus-mediated Bcl-2 expression in βTC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion Gene Therapy. 6: 1160-1169. PMID 10455420 DOI: 10.1038/Sj.Gt.3300922 |
0.33 |
|
1999 |
Han JJ, Mhatre AN, Wareing M, Pettis R, Gao WQ, Zufferey RN, Trono D, Lalwani AK. Transgene expression in the guinea pig cochlea mediated by a lentivirus-derived gene transfer vector. Human Gene Therapy. 10: 1867-73. PMID 10446926 DOI: 10.1089/10430349950017545 |
0.392 |
|
1999 |
Piguet V, Schwartz O, Le Gall S, Trono D. The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors. Immunological Reviews. 168: 51-63. PMID 10399064 DOI: 10.1111/J.1600-065X.1999.Tb01282.X |
0.346 |
|
1999 |
Piguet V, Trono D. The Nef protein of primate lentiviruses. Reviews in Medical Virology. 9: 111-20. PMID 10386338 DOI: 10.1002/(Sici)1099-1654(199904/06)9:2<111::Aid-Rmv245>3.0.Co;2-P |
0.408 |
|
1999 |
Lama J, Mangasarian A, Trono D. Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner. Current Biology : Cb. 9: 622-31. PMID 10375528 DOI: 10.1016/S0960-9822(99)80284-X |
0.363 |
|
1999 |
Zufferey R, Donello JE, Trono D, Hope TJ. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors Journal of Virology. 73: 2886-2892. PMID 10074136 DOI: 10.1128/Jvi.73.4.2886-2892.1999 |
0.404 |
|
1999 |
Mangasarian A, Piguet V, Wang J, Chen Y, Trono D. Nef-Induced CD4 and Major Histocompatibility Complex Class I (MHC-I) Down-Regulation Are Governed by Distinct Determinants: N-Terminal Alpha Helix and Proline Repeat of Nef Selectively Regulate MHC-I Trafficking Journal of Virology. 73: 1964-1973. DOI: 10.1128/Jvi.73.3.1964-1973.1999 |
0.349 |
|
1998 |
Zufferey R, Dull T, Mandel RJ, Bukovsky A, Quiroz D, Naldini L, Trono D. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. Journal of Virology. 72: 9873-80. PMID 9811723 DOI: 10.1128/Jvi.72.12.9873-9880.1998 |
0.411 |
|
1998 |
Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, Trono D, Naldini L. A third-generation lentivirus vector with a conditional packaging system. Journal of Virology. 72: 8463-71. PMID 9765382 DOI: 10.1128/Jvi.72.11.8463-8471.1998 |
0.428 |
|
1998 |
Piguet V, Chen YL, Mangasarian A, Foti M, Carpentier JL, Trono D. Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes. The Embo Journal. 17: 2472-81. PMID 9564030 DOI: 10.1093/Emboj/17.9.2472 |
0.333 |
|
1998 |
Chen Y, Trono D, Camaur D. The Proteolytic Cleavage of Human Immunodeficiency Virus Type 1 Nef Does Not Correlate with Its Ability To Stimulate Virion Infectivity Journal of Virology. 72: 3178-3184. DOI: 10.1128/Jvi.72.4.3178-3184.1998 |
0.362 |
|
1998 |
Lama J, Trono D. Human Immunodeficiency Virus Type 1 Matrix Protein Interacts with Cellular Protein HO3 Journal of Virology. 72: 1671-1676. DOI: 10.1128/Jvi.72.2.1671-1676.1998 |
0.387 |
|
1998 |
Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, Trono D, Naldini L. A Third-Generation Lentivirus Vector with a Conditional Packaging System Journal of Virology. 72: 8463-8471. DOI: 10.1128/jvi.72.11.8463-8471.1998 |
0.318 |
|
1997 |
Zufferey R, Nagy D, Mandel RJ, Naldini L, Trono D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nature Biotechnology. 15: 871-5. PMID 9306402 DOI: 10.1038/Nbt0997-871 |
0.42 |
|
1997 |
Gallay P, Hope T, Chin D, Trono D. HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway. Proceedings of the National Academy of Sciences of the United States of America. 94: 9825-30. PMID 9275210 DOI: 10.1073/Pnas.94.18.9825 |
0.4 |
|
1997 |
Blömer U, Naldini L, Kafri T, Trono D, Verma IM, Gage FH. Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector. Journal of Virology. 71: 6641-9. PMID 9261386 DOI: 10.1128/Jvi.71.9.6641-6649.1997 |
0.402 |
|
1997 |
Trono D, Wang JK. Nef and PAK: Virulence factor and cellular accomplice Chemistry and Biology. 4: 13-15. PMID 9070423 DOI: 10.1016/S1074-5521(97)90232-5 |
0.327 |
|
1997 |
Mangasarian A, Foti M, Aiken C, Chin D, Carpentier JL, Trono D. The HIV-1 net protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane Immunity. 6: 67-77. PMID 9052838 DOI: 10.1016/S1074-7613(00)80243-5 |
0.312 |
|
1997 |
Camaur D, Gallay P, Swingler S, Trono D. Human immunodeficiency virus matrix tyrosine phosphorylation: characterization of the kinase and its substrate requirements. Journal of Virology. 71: 6834-6841. DOI: 10.1128/Jvi.71.9.6834-6841.1997 |
0.342 |
|
1997 |
Trono D, Gallay P. In Response to Freed et al Cell. 88: 173-174. DOI: 10.1016/S0092-8674(00)81837-1 |
0.323 |
|
1996 |
Naldini L, Blömer U, Gage FH, Trono D, Verma IM. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proceedings of the National Academy of Sciences of the United States of America. 93: 11382-8. PMID 8876144 DOI: 10.1073/Pnas.93.21.11382 |
0.37 |
|
1996 |
Blömer U, Naldini L, Verma IM, Trono D, Gage FH. Applications of gene therapy to the CNS. Human Molecular Genetics. 5: 1397-404. PMID 8875243 DOI: 10.1093/Hmg/5.Supplement_1.1397 |
0.365 |
|
1996 |
Naldini L, Blömer U, Gallay P, Ory D, Mulligan R, Gage FH, Verma IM, Trono D. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science (New York, N.Y.). 272: 263-7. PMID 8602510 DOI: 10.1126/Science.272.5259.263 |
0.45 |
|
1996 |
Aiken C, Krause L, Chen YL, Trono D. Mutational analysis of HIV-1 Nef: Identification of two mutants that are temperature-sensitive for CD4 downregulation Virology. 217: 293-300. PMID 8599214 DOI: 10.1006/Viro.1996.0116 |
0.341 |
|
1996 |
Gallay P, Stitt V, Mundy C, Oettinger M, Trono D. Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import. Journal of Virology. 70: 1027-1032. DOI: 10.1128/Jvi.70.2.1027-1032.1996 |
0.364 |
|
1995 |
Gallay P, Swingler S, Aiken C, Trono D. HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator Cell. 80: 379-388. PMID 7859280 DOI: 10.1016/0092-8674(95)90488-3 |
0.374 |
|
1995 |
Koval V, Jault FM, Pal PG, Moreno TN, Aiken C, Trono D, Spector SA, Spector DH. Differential effects of human cytomegalovirus on integrated and unintegrated human immunodeficiency virus sequences Journal of Virology. 69: 1645-1651. PMID 7853500 DOI: 10.1128/Jvi.69.3.1645-1651.1995 |
0.373 |
|
1995 |
Trono D. HIV accessory proteins: leading roles for the supporting cast. Cell. 82: 189-92. PMID 7628010 DOI: 10.1016/0092-8674(95)90306-2 |
0.311 |
|
1995 |
Gallay P, Swingler S, Song J, Bushman F, Trono D. HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase. Cell. 83: 569-76. PMID 7585960 DOI: 10.1016/0092-8674(95)90097-7 |
0.347 |
|
1995 |
Aiken C, Trono D. Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis Journal of Virology. 69: 5048-5056. PMID 7541845 DOI: 10.1128/Jvi.69.8.5048-5056.1995 |
0.405 |
|
1994 |
Aiken C, Konner J, Landau NR, Lenburg ME, Trono D. Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell. 76: 853-64. PMID 8124721 DOI: 10.1016/0092-8674(94)90360-3 |
0.302 |
|
1994 |
von Schwedler U, Kornbluth RS, Trono D. The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 91: 6992-6. PMID 8041734 DOI: 10.1073/Pnas.91.15.6992 |
0.392 |
|
1993 |
Winslow BJ, Pomerantz RJ, Bagasra O, Trono D. HIV-1 latency due to the site of proviral integration. Virology. 196: 849-54. PMID 8372452 DOI: 10.1006/Viro.1993.1545 |
0.411 |
|
1993 |
Von Schwedler U, Song J, Aiken C, Trono D. vif Is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells Journal of Virology. 67: 4945-4955. PMID 8331734 DOI: 10.1128/Jvi.67.8.4945-4955.1993 |
0.433 |
|
1992 |
Feinberg MB, Trono D. Intracellular immunization: trans-dominant mutants of HIV gene products as tools for the study and interruption of viral replication. Aids Research and Human Retroviruses. 8: 1013-22. PMID 1503816 DOI: 10.1089/Aid.1992.8.1013 |
0.358 |
|
1992 |
Trono D. Partial reverse transcripts in virions from human immunodeficiency and murine leukemia viruses. Journal of Virology. 66: 4893-4900. PMID 1378513 DOI: 10.1128/Jvi.66.8.4893-4900.1992 |
0.376 |
|
1992 |
Seshamma T, Bagasra O, Trono D, Baltimore D, Pomerantz RJ. Blocked early-stage latency in the peripheral blood cells of certain individuals infected with human immunodeficiency virus type 1. Proceedings of the National Academy of Sciences of the United States of America. 89: 10663-7. PMID 1279688 DOI: 10.1073/Pnas.89.22.10663 |
0.351 |
|
1992 |
Pomerantz RJ, Seshamma T, Trono D. Efficient replication of human immunodeficiency virus type 1 requires a threshold level of Rev: potential implications for latency. Journal of Virology. 66: 1809-1813. DOI: 10.1128/Jvi.66.3.1809-1813.1992 |
0.386 |
|
1990 |
Trono D, Baltimore D. A human cell factor is essential for HIV-1 Rev action. The Embo Journal. 9: 4155-4160. DOI: 10.1002/j.1460-2075.1990.tb07638.x |
0.303 |
|
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