David W. Pascual - Publications

Affiliations: 
Veterinary Molecular Biology Montana State University, Bozeman, MT 
Area:
Immunology, Molecular Biology

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yang X, Goodwin ZI, Bhagyaraj E, Hoffman C, Pascual DW. Parenteral Vaccination with a Live Mutant Protects against Wild-Type 16M Challenge. Microorganisms. 12. PMID 38257995 DOI: 10.3390/microorganisms12010169  0.417
2023 Akgul A, Freguia CF, Maddaloni M, Hoffman C, Voigt A, Nguyen CQ, Fanger NA, Fanger GR, Pascual DW. Treatment with a Lactococcus lactis that chromosomally express E. coli cfaI mitigates salivary flow loss in a Sjögren's syndrome-like disease. Scientific Reports. 13: 19489. PMID 37945636 DOI: 10.1038/s41598-023-46557-3  0.324
2023 Wang H, Clapp B, Hoffman C, Yang X, Pascual DW. A Single Nasal Dose Vaccination with a Brucella abortus Mutant Potently Protects against Pulmonary Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 37036290 DOI: 10.4049/jimmunol.2300071  0.405
2022 Pascual DW, Goodwin ZI, Bhagyaraj E, Hoffman C, Yang X. Activation of mucosal immunity as a novel therapeutic strategy for combating brucellosis. Frontiers in Microbiology. 13: 1018165. PMID 36620020 DOI: 10.3389/fmicb.2022.1018165  0.355
2022 Goodwin ZI, Yang X, Hoffman C, Pascual DW. Live mucosal vaccination stimulates potent protection varied CD4 and CD8 T cell subsets against wild-type 16M challenge. Frontiers in Immunology. 13: 995327. PMID 36263034 DOI: 10.3389/fimmu.2022.995327  0.409
2021 Nelson AS, Akgul A, Maddaloni M, Bhagyaraj E, Hoffman C, Pascual DW. Oral probiotic promotes indoleamine 2,3-dioxygenase- and TGF-β-producing plasmacytoid dendritic cells to initiate protection against type 1 diabetes. Immunology Letters. PMID 34333043 DOI: 10.1016/j.imlet.2021.07.009  0.353
2021 Bhagyaraj E, Wang H, Yang X, Hoffman C, Akgul A, Goodwin ZI, Pascual DW. Mucosal Vaccination Primes NK Cell-Dependent Development of CD8 T Cells Against Pulmonary Infection. Frontiers in Immunology. 12: 697953. PMID 34305935 DOI: 10.3389/fimmu.2021.697953  0.419
2021 Hui WW, Emerson LE, Clapp B, Sheppe AE, Sharma J, Del Castillo J, Ou M, Maegawa GHB, Hoffman C, Larkin Iii J, Pascual DW, Edelmann MJ. Antigen-encapsulating host extracellular vesicles derived from Salmonella-infected cells stimulate pathogen-specific Th1-type responses in vivo. Plos Pathogens. 17: e1009465. PMID 33956909 DOI: 10.1371/journal.ppat.1009465  0.344
2020 Maślanka T, Clapp B, Hoffman C, Robison A, Gregorczyk I, Pascual DW. Nasal vaccination of β7 integrin-deficient mice retains elevated IgA immunity. Immunology and Cell Biology. PMID 32479679 DOI: 10.1111/Imcb.12364  0.43
2020 Nelson AS, Maddaloni M, Abbott JR, Hoffman C, Akgul A, Ohland C, Gharaibeh RZ, Jobin C, Brusko TM, Pascual DW. Oral therapy with colonization factor antigen I prevents development of type 1 diabetes in Non-obese Diabetic mice. Scientific Reports. 10: 6156. PMID 32273533 DOI: 10.1038/S41598-020-62881-4  0.45
2020 Wang H, Hoffman C, Yang X, Clapp B, Pascual DW. Targeting resident memory T cell immunity culminates in pulmonary and systemic protection against Brucella infection. Plos Pathogens. 16: e1008176. PMID 31951645 DOI: 10.1371/Journal.Ppat.1008176  0.495
2019 Jones DI, Pollara JJ, Johnson-Weaver BT, LaBranche CC, Montefiori DC, Pickup DJ, Permar SR, Abraham SN, Maddaloni M, Pascual DW, Staats HF. Optimized Mucosal MVA Prime/Soluble gp120 Boost Vaccination Regimen Induces Similar Antibody Responses as an Intramuscular Regimen. Journal of Virology. PMID 31068425 DOI: 10.1128/Jvi.00475-19  0.452
2018 Crosby FL, Lundgren AM, Hoffman C, Pascual DW, Barbet AF. VirB10 vaccination for protection against Anaplasma phagocytophilum. Bmc Microbiology. 18: 217. PMID 30563470 DOI: 10.1186/S12866-018-1346-X  0.391
2018 Maddaloni M, Kochetkova I, Hoffman C, Pascual DW. Delivery of IL-35 by Ameliorates Collagen-Induced Arthritis in Mice. Frontiers in Immunology. 9: 2691. PMID 30515168 DOI: 10.3389/Fimmu.2018.02691  0.439
2018 Li X, Shao Y, Sha X, Fang P, Kuo YM, Andrews AJ, Li Y, Yang WY, Maddaloni M, Pascual DW, Luo JJ, Jiang X, Wang H, Yang X. IL-35 (Interleukin-35) Suppresses Endothelial Cell Activation by Inhibiting Mitochondrial Reactive Oxygen Species-Mediated Site-Specific Acetylation of H3K14 (Histone 3 Lysine 14). Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29371247 DOI: 10.1161/Atvbaha.117.310626  0.438
2018 Li X, Shao Y, Sha X, Fang P, Kuo Y, Andrews AJ, Li Y, Yang WY, Maddaloni M, Pascual DW, Luo JJ, Jiang X, Wang H, Yang X. Abstract 029: Interleukin-35 Suppresses Endothelial Activation by Inhibiting Mitochondrial Reactive Oxygen Species Mediated Site-specific Acetylation of Histone 3 Lysine 14 Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.029  0.338
2017 Pascual DW, Yang X, Wang H, Goodwin Z, Hoffman C, Clapp B. Alternative Strategies for Vaccination to Brucellosis. Microbes and Infection. PMID 29287984 DOI: 10.1016/J.Micinf.2017.12.006  0.403
2016 Yang X, Clapp B, Thornburg T, Hoffman C, Pascual DW. Vaccination with a ΔnorD ΔznuA Brucella abortus mutant confers potent protection against virulent challenge. Vaccine. PMID 27639282 DOI: 10.1016/J.Vaccine.2016.09.004  0.482
2016 Huarte E, Jun S, Rynda-Apple A, Golden S, Jackiw L, Hoffman C, Maddaloni M, Pascual DW. Regulatory T Cell Dysfunction Acquiesces to BTLA+ Regulatory B Cells Subsequent to Oral Intervention in Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 27194787 DOI: 10.4049/Jimmunol.1501973  0.723
2016 Goodwin ZI, Pascual DW. Brucellosis vaccines for livestock. Veterinary Immunology and Immunopathology. PMID 27032465 DOI: 10.1016/J.Vetimm.2016.03.011  0.404
2016 Clapp B, Yang X, Thornburg T, Walters N, Pascual DW. Nasal vaccination stimulates CD8(+) T cells for potent protection against mucosal Brucella melitensis challenge. Immunology and Cell Biology. PMID 26752510 DOI: 10.1038/Icb.2016.5  0.547
2015 Sha X, Meng S, Li X, Xi H, Maddaloni M, Pascual DW, Shan H, Jiang X, Wang H, Yang XF. Interleukin-35 Inhibits Endothelial Cell Activation by Suppressing MAPK-AP-1 Pathway. The Journal of Biological Chemistry. PMID 26085094 DOI: 10.1074/Jbc.M115.663286  0.39
2015 Maddaloni M, Kochetkova I, Jun S, Callis G, Thornburg T, Pascual DW. Milk-based nutraceutical for treating autoimmune arthritis via the stimulation of IL-10- and TGF-β-producing CD39+ regulatory T cells. Plos One. 10: e0117825. PMID 25629976 DOI: 10.1371/Journal.Pone.0117825  0.732
2014 Pascual DW, Yang X, Holderness K, Jun S, Maddaloni M, Kochetkova I. Regulatory T-cell vaccination independent of auto-antigen. Experimental & Molecular Medicine. 46: e82. PMID 24626168 DOI: 10.1038/Emm.2014.4  0.731
2014 Kochetkova I, Thornburg T, Callis G, Holderness K, Maddaloni M, Pascual DW. Oral Escherichia coli colonization factor antigen I fimbriae ameliorate arthritis via IL-35, not IL-27. Journal of Immunology (Baltimore, Md. : 1950). 192: 804-16. PMID 24337375 DOI: 10.4049/Jimmunol.1302018  0.48
2013 Kouakou K, Schepetkin IA, Jun S, Kirpotina LN, Yapi A, Khramova DS, Pascual DW, Ovodov YS, Jutila MA, Quinn MT. Immunomodulatory activity of polysaccharides isolated from Clerodendrum splendens: beneficial effects in experimental autoimmune encephalomyelitis. Bmc Complementary and Alternative Medicine. 13: 149. PMID 23806004 DOI: 10.1186/1472-6882-13-149  0.684
2013 Skyberg JA, Rollins MF, Samuel JW, Sutherland MD, Belisle JT, Pascual DW. Interleukin-17 protects against the Francisella tularensis live vaccine strain but not against a virulent F. tularensis type A strain. Infection and Immunity. 81: 3099-105. PMID 23774604 DOI: 10.1128/Iai.00203-13  0.416
2013 Yang X, Skyberg JA, Cao L, Clapp B, Thornburg T, Pascual DW. Progress in Brucella vaccine development. Frontiers in Biology. 8: 60-77. PMID 23730309 DOI: 10.1007/S11515-012-1196-0  0.391
2013 Pascual DW, Suo Z, Cao L, Avci R, Yang X. Attenuating gene expression (AGE) for vaccine development. Virulence. 4: 384-90. PMID 23652809 DOI: 10.4161/Viru.24886  0.419
2013 Vicente S, Diaz-Freitas B, Peleteiro M, Sanchez A, Pascual DW, Gonzalez-Fernandez A, Alonso MJ. A polymer/oil based nanovaccine as a single-dose immunization approach. Plos One. 8: e62500. PMID 23614052 DOI: 10.1371/Journal.Pone.0062500  0.391
2012 Hendricks JM, Hoffman C, Pascual DW, Hardy ME. 18β-glycyrrhetinic acid delivered orally induces isolated lymphoid follicle maturation at the intestinal mucosa and attenuates rotavirus shedding. Plos One. 7: e49491. PMID 23152913 DOI: 10.1371/Journal.Pone.0049491  0.42
2012 Yang X, Thornburg T, Suo Z, Jun S, Robison A, Li J, Lim T, Cao L, Hoyt T, Avci R, Pascual DW. Flagella overexpression attenuates Salmonella pathogenesis. Plos One. 7: e46828. PMID 23056473 DOI: 10.1371/Journal.Pone.0046828  0.683
2012 Skyberg JA, Thornburg T, Kochetkova I, Layton W, Callis G, Rollins MF, Riccardi C, Becker T, Golden S, Pascual DW. IFN-γ-deficient mice develop IL-1-dependent cutaneous and musculoskeletal inflammation during experimental brucellosis. Journal of Leukocyte Biology. 92: 375-87. PMID 22636321 DOI: 10.1189/Jlb.1211626  0.4
2012 Zlotkowska D, Maddaloni M, Riccardi C, Walters N, Holderness K, Callis G, Rynda-Apple A, Pascual DW. Loss of sialic acid binding domain redirects protein σ1 to enhance M cell-directed vaccination. Plos One. 7: e36182. PMID 22558374 DOI: 10.1371/Journal.Pone.0036182  0.48
2012 Skyberg JA, Rollins MF, Holderness JS, Marlenee NL, Schepetkin IA, Goodyear A, Dow SW, Jutila MA, Pascual DW. Nasal Acai polysaccharides potentiate innate immunity to protect against pulmonary Francisella tularensis and Burkholderia pseudomallei Infections. Plos Pathogens. 8: e1002587. PMID 22438809 DOI: 10.1371/Journal.Ppat.1002587  0.373
2012 Schepetkin IA, Kirpotina LN, Khlebnikov AI, Hanks TS, Kochetkova I, Pascual DW, Jutila MA, Quinn MT. Identification and characterization of a novel class of c-Jun N-terminal kinase inhibitors. Molecular Pharmacology. 81: 832-45. PMID 22434859 DOI: 10.1124/Mol.111.077446  0.378
2012 Jun S, Ochoa-Repáraz J, Zlotkowska D, Hoyt T, Pascual DW. Bystander-mediated stimulation of proteolipid protein-specific regulatory T (Treg) cells confers protection against experimental autoimmune encephalomyelitis (EAE) via TGF-β. Journal of Neuroimmunology. 245: 39-47. PMID 22418032 DOI: 10.1016/J.Jneuroim.2012.02.003  0.764
2012 Yang X, Suo Z, Thornburg T, Holderness K, Cao L, Lim T, Walters N, Kellerman L, Loetterle L, Avci R, Pascual DW. Expression of Escherichia coli virulence usher protein attenuates wild-type Salmonella. Virulence. 3: 29-42. PMID 22286706 DOI: 10.4161/Viru.3.1.18447  0.395
2012 Jun S, Clapp B, Zlotkowska D, Hoyt T, Holderness K, Maddaloni M, Pascual DW. Sublingual immunization with adenovirus F protein-based vaccines stimulates protective immunity against botulinum neurotoxin A intoxication. International Immunology. 24: 117-28. PMID 22207133 DOI: 10.1093/Intimm/Dxr106  0.746
2012 Yamamoto M, Pascual DW, Kiyono H. M cell-targeted mucosal vaccine strategies Current Topics in Microbiology and Immunology. 354: 39-52. PMID 21688209 DOI: 10.1007/82_2011_134  0.461
2011 Huarte E, Rynda-Apple A, Riccardi C, Skyberg JA, Golden S, Rollins MF, Ramstead AG, Jackiw LO, Maddaloni M, Pascual DW. Tolerogen-induced interferon-producing killer dendritic cells (IKDCs) protect against EAE. Journal of Autoimmunity. 37: 328-41. PMID 22018711 DOI: 10.1016/J.Jaut.2011.09.005  0.439
2011 Yang X, Thornburg T, Holderness K, Suo Z, Cao L, Lim T, Avci R, Pascual DW. Serum antibodies protect against intraperitoneal challenge with enterotoxigenic Escherichia coli. Journal of Biomedicine & Biotechnology. 2011: 632396. PMID 22007145 DOI: 10.1155/2011/632396  0.466
2011 Kochetkova I, Thornburg T, Callis G, Pascual DW. Segregated regulatory CD39+CD4+ T cell function: TGF-β-producing Foxp3- and IL-10-producing Foxp3+ cells are interdependent for protection against collagen-induced arthritis. Journal of Immunology (Baltimore, Md. : 1950). 187: 4654-66. PMID 21967895 DOI: 10.4049/Jimmunol.1100530  0.455
2011 Clapp B, Skyberg JA, Yang X, Thornburg T, Walters N, Pascual DW. Protective live oral brucellosis vaccines stimulate Th1 and th17 cell responses. Infection and Immunity. 79: 4165-74. PMID 21768283 DOI: 10.1128/Iai.05080-11  0.488
2011 Skyberg JA, Thornburg T, Rollins M, Huarte E, Jutila MA, Pascual DW. Murine and bovine γδ T cells enhance innate immunity against Brucella abortus infections. Plos One. 6: e21978. PMID 21765931 DOI: 10.1371/Journal.Pone.0021978  0.462
2011 Clapp B, Walters N, Thornburg T, Hoyt T, Yang X, Pascual DW. DNA vaccination of bison to brucellar antigens elicits elevated antibody and IFN-γ responses. Journal of Wildlife Diseases. 47: 501-10. PMID 21719815 DOI: 10.7589/0090-3558-47.3.501  0.472
2011 Skyberg JA, Robison A, Golden S, Rollins MF, Callis G, Huarte E, Kochetkova I, Jutila MA, Pascual DW. Apple polyphenols require T cells to ameliorate dextran sulfate sodium-induced colitis and dampen proinflammatory cytokine expression. Journal of Leukocyte Biology. 90: 1043-54. PMID 21693591 DOI: 10.1189/Jlb.0311168  0.511
2011 Staats HF, Fielhauer JR, Thompson AL, Tripp AA, Sobel AE, Maddaloni M, Abraham SN, Pascual DW. Mucosal targeting of a BoNT/A subunit vaccine adjuvanted with a mast cell activator enhances induction of BoNT/A neutralizing antibodies in rabbits. Plos One. 6: e16532. PMID 21304600 DOI: 10.1371/Journal.Pone.0016532  0.399
2011 Rynda-Apple A, Huarte E, Maddaloni M, Callis G, Skyberg JA, Pascual DW. Active immunization using a single dose immunotherapeutic abates established EAE via IL-10 and regulatory T cells. European Journal of Immunology. 41: 313-23. PMID 21268002 DOI: 10.1002/Eji.201041104  0.449
2010 Clapp B, Golden S, Maddaloni M, Staats HF, Pascual DW. Adenovirus F protein as a delivery vehicle for botulinum B. Bmc Immunology. 11: 36. PMID 20609248 DOI: 10.1186/1471-2172-11-36  0.495
2010 Kochetkova I, Golden S, Holderness K, Callis G, Pascual DW. IL-35 stimulation of CD39+ regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10. Journal of Immunology (Baltimore, Md. : 1950). 184: 7144-53. PMID 20483737 DOI: 10.4049/Jimmunol.0902739  0.466
2010 Yamanaka H, Hoyt T, Yang X, Bowen R, Golden S, Crist K, Becker T, Maddaloni M, Pascual DW. A parenteral DNA vaccine protects against pneumonic plague. Vaccine. 28: 3219-30. PMID 20197132 DOI: 10.1016/J.Vaccine.2010.02.022  0.451
2010 Rynda A, Maddaloni M, Ochoa-Repáraz J, Callis G, Pascual DW. IL-28 supplants requirement for T(reg) cells in protein sigma1-mediated protection against murine experimental autoimmune encephalomyelitis (EAE). Plos One. 5: e8720. PMID 20090936 DOI: 10.1371/Journal.Pone.0008720  0.798
2010 Yang X, Thornburg T, Walters N, Pascual DW. DeltaznuADeltapurE Brucella abortus 2308 mutant as a live vaccine candidate. Vaccine. 28: 1069-74. PMID 19914192 DOI: 10.1016/J.Vaccine.2009.10.113  0.368
2009 Suo Z, Yang X, Avci R, Deliorman M, Rugheimer P, Pascual DW, Idzerda Y. Antibody selection for immobilizing living bacteria. Analytical Chemistry. 81: 7571-8. PMID 19681578 DOI: 10.1021/Ac9014484  0.31
2009 Suo Z, Avci R, Deliorman M, Yang X, Pascual DW. Bacteria survive multiple puncturings of their cell walls. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 4588-94. PMID 19260649 DOI: 10.1021/La8033319  0.313
2009 Yamanaka H, Hoyt T, Bowen R, Yang X, Crist K, Golden S, Maddaloni M, Pascual DW. An IL-12 DNA vaccine co-expressing Yersinia pestis antigens protects against pneumonic plague. Vaccine. 27: 80-7. PMID 18955097 DOI: 10.1016/J.Vaccine.2008.10.021  0.495
2009 Skyberg JA, Jutila MA, Pascual DW. Protective role for γδ T cells in the innate immune response against Brucella abortus Veterinary Immunology and Immunopathology. 128: 228. DOI: 10.1016/J.Vetimm.2008.10.041  0.455
2008 Pascual DW, Riccardi C, Csencsits-Smith K. Distal IgA immunity can be sustained by αE β7+ B cells in L-selectin-/- mice following oral immunization Mucosal Immunology. 1: 68-77. PMID 19079162 DOI: 10.1038/Mi.2007.2  0.438
2008 Yamanaka H, Hoyt T, Yang X, Golden S, Bosio CM, Crist K, Becker T, Maddaloni M, Pascual DW. A nasal interleukin-12 DNA vaccine coexpressing Yersinia pestis F1-V fusion protein confers protection against pneumonic plague Infection and Immunity. 76: 4564-4573. PMID 18694965 DOI: 10.1128/Iai.00581-08  0.443
2008 Kochetkova I, Trunkle T, Callis G, Pascual DW. Vaccination without autoantigen protects against collagen II-induced arthritis via immune deviation and regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 2741-52. PMID 18684965 DOI: 10.4049/Jimmunol.181.4.2741  0.551
2008 Pascual DW, Wang X, Kochetkova I, Callis G, Riccardi C. The absence of lymphoid CD8+ dendritic cell maturation in L-selectin-/- respiratory compartment attenuates antiviral immunity. Journal of Immunology (Baltimore, Md. : 1950). 181: 1345-56. PMID 18606689 DOI: 10.4049/Jimmunol.181.2.1345  0.397
2008 Ochoa-Repáraz J, Rynda A, Ascón MA, Yang X, Kochetkova I, Riccardi C, Callis G, Trunkle T, Pascual DW. IL-13 production by regulatory T cells protects against experimental autoimmune encephalomyelitis independently of autoantigen. Journal of Immunology (Baltimore, Md. : 1950). 181: 954-68. PMID 18606647 DOI: 10.4049/Jimmunol.181.2.954  0.829
2008 Suzuki H, Sekine S, Kataoka K, Pascual DW, Maddaloni M, Kobayashi R, Fujihashi K, Kozono H, McGhee JR, Fujihashi K. Ovalbumin-protein sigma 1 M-cell targeting facilitates oral tolerance with reduction of antigen-specific CD4+ T cells. Gastroenterology. 135: 917-25. PMID 18565333 DOI: 10.1053/J.Gastro.2008.05.037  0.496
2008 Rynda A, Maddaloni M, Mierzejewska D, Ochoa-Repáraz J, Maslanka T, Crist K, Riccardi C, Barszczewska B, Fujihashi K, McGhee JR, Pascual DW. Low-dose tolerance is mediated by the microfold cell ligand, reovirus protein sigma1. Journal of Immunology (Baltimore, Md. : 1950). 180: 5187-200. PMID 18390700 DOI: 10.4049/Jimmunol.180.8.5187  0.808
2008 Suo Z, Avci R, Yang X, Pascual DW. Efficient immobilization and patterning of live bacterial cells. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 4161-7. PMID 18321142 DOI: 10.1021/La7038653  0.313
2007 Pascual DW, Ochoa-Repáraz J, Rynda A, Yang X. Tolerance in the absence of autoantigen. Endocrine, Metabolic & Immune Disorders Drug Targets. 7: 203-10. PMID 17897047 DOI: 10.2174/187153007781662549  0.83
2007 Ochoa-Repáraz J, Sentissi J, Trunkle T, Riccardi C, Pascual DW. Attenuated Coxiella burnetii phase II causes a febrile response in gamma interferon knockout and Toll-like receptor 2 knockout mice and protects against reinfection. Infection and Immunity. 75: 5845-58. PMID 17893129 DOI: 10.1128/Iai.00901-07  0.435
2007 Pascual DW. Vaccines are for dinner. Proceedings of the National Academy of Sciences of the United States of America. 104: 10757-8. PMID 17581867 DOI: 10.1073/Pnas.0704516104  0.38
2007 Hedges JF, Buckner DL, Rask KM, Kerns HM, Jackiw LO, Trunkle TC, Pascual DW, Jutila MA. Mucosal lymphatic-derived gammadelta T cells respond early to experimental Salmonella enterocolitis by increasing expression of IL-2R alpha. Cellular Immunology. 246: 8-16. PMID 17574223 DOI: 10.1016/J.Cellimm.2007.04.006  0.449
2007 Fujihashi K, Staats HF, Kozaki S, Pascual DW. Mucosal vaccine development for botulinum intoxication. Expert Review of Vaccines. 6: 35-45. PMID 17280477 DOI: 10.1586/14760584.6.1.35  0.44
2007 Yang X, Walters N, Robison A, Trunkle T, Pascual DW. Nasal immunization with recombinant Brucella melitensis bp26 and trigger factor with cholera toxin reduces B. melitensis colonization. Vaccine. 25: 2261-8. PMID 17239499 DOI: 10.1016/J.Vaccine.2006.12.004  0.457
2007 Ochoa-Repáraz J, Riccardi C, Rynda A, Jun S, Callis G, Pascual DW. Regulatory T cell vaccination without autoantigen protects against experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 178: 1791-9. PMID 17237429 DOI: 10.4049/Jimmunol.178.3.1791  0.803
2007 Yang X, Hinnebusch BJ, Trunkle T, Bosio CM, Suo Z, Tighe M, Harmsen A, Becker T, Crist K, Walters N, Avci R, Pascual DW. Oral vaccination with Salmonella simultaneously expressing Yersinia pestis F1 and V antigens protects against bubonic and pneumonic plague Journal of Immunology. 178: 1059-1067. PMID 17202369 DOI: 10.4049/Jimmunol.178.2.1059  0.353
2006 Maddaloni M, Staats HF, Mierzejewska D, Hoyt T, Robinson A, Callis G, Kozaki S, Kiyono H, McGhee JR, Fujihashi K, Pascual DW. Mucosal vaccine targeting improves onset of mucosal and systemic immunity to botulinum neurotoxin A. Journal of Immunology (Baltimore, Md. : 1950). 177: 5524-32. PMID 17015739 DOI: 10.4049/Jimmunol.177.8.5524  0.491
2006 Yang X, Becker T, Walters N, Pascual DW. Deletion of znuA virulence factor attenuates Brucella abortus and confers protection against wild-type challenge. Infection and Immunity. 74: 3874-9. PMID 16790759 DOI: 10.1128/Iai.01957-05  0.346
2005 Jun S, Gilmore W, Callis G, Rynda A, Haddad A, Pascual DW. A live diarrheal vaccine imprints a Th2 cell bias and acts as an anti-inflammatory vaccine. Journal of Immunology (Baltimore, Md. : 1950). 175: 6733-40. PMID 16272329 DOI: 10.4049/Jimmunol.175.10.6733  0.801
2005 Yang X, Hudson M, Walters N, Bargatze RF, Pascual DW. Selection of protective epitopes for Brucella melitensis by DNA vaccination. Infection and Immunity. 73: 7297-303. PMID 16239526 DOI: 10.1128/Iai.73.11.7297-7303.2005  0.477
2005 Ascón MA, Ochoa-Repáraz J, Walters N, Pascual DW. Partially assembled K99 fimbriae are required for protection. Infection and Immunity. 73: 7274-80. PMID 16239523 DOI: 10.1128/Iai.73.11.7274-7280.2005  0.391
2005 Wang X, Kochetkova I, Haddad A, Hoyt T, Hone DM, Pascual DW. Transgene vaccination using Ulex europaeus agglutinin I (UEA-1) for targeted mucosal immunization against HIV-1 envelope. Vaccine. 23: 3836-42. PMID 15893622 DOI: 10.1016/J.Vaccine.2005.02.023  0.455
2005 Kobayashi R, Kohda T, Kataoka K, Ihara H, Kozaki S, Pascual DW, Staats HF, Kiyono H, McGhee JR, Fujihashi K. A novel neurotoxoid vaccine prevents mucosal botulism. Journal of Immunology (Baltimore, Md. : 1950). 174: 2190-5. PMID 15699151 DOI: 10.4049/Jimmunol.174.4.2190  0.457
2005 Walters N, Trunkle T, Sura M, Pascual DW. Enhanced immunoglobulin A response and protection against Salmonella enterica serovar typhimurium in the absence of the substance P receptor. Infection and Immunity. 73: 317-24. PMID 15618168 DOI: 10.1128/Iai.73.1.317-324.2005  0.527
2005 Piller KJ, Clemente TE, Jun SM, Petty CC, Sato S, Pascual DW, Bost KL. Expression and immunogenicity of an Escherichia coli K99 fimbriae subunit antigen in soybean. Planta. 222: 6-18. PMID 15609046 DOI: 10.1007/S00425-004-1445-9  0.714
2004 Pascual DW. The role of tachykinins on bacterial infections. Frontiers in Bioscience : a Journal and Virtual Library. 9: 3209-17. PMID 15353350 DOI: 10.2741/1473  0.357
2003 Wang X, Hillemeyer P, Pascual DW. Segregation of mechanisms for cytotoxic T lymphocyte killing between lungs and regional lymph nodes subsequent to intratracheal delivery of adenovirus 2 vector. Viral Immunology. 16: 525-39. PMID 14733739 DOI: 10.1089/088282403771926346  0.451
2003 Wang X, Hone DM, Haddad A, Shata MT, Pascual DW. M cell DNA vaccination for CTL immunity to HIV. Journal of Immunology (Baltimore, Md. : 1950). 171: 4717-25. PMID 14568947 DOI: 10.4049/Jimmunol.171.9.4717  0.466
2002 Csencsits KL, Pascual DW. Absence of L-selectin delays mucosal B cell responses in nonintestinal effector tissues. Journal of Immunology (Baltimore, Md. : 1950). 169: 5649-59. PMID 12421944 DOI: 10.4049/Jimmunol.169.10.5649  0.76
2002 Csencsits KL, Jutila MA, Pascual DW. Mucosal addressin expression and binding-interactions with naive lymphocytes vary among the cranial, oral, and nasal-associated lymphoid tissues. European Journal of Immunology. 32: 3029-39. PMID 12385022 DOI: 10.1002/1521-4141(200211)32:11<3029::Aid-Immu3029>3.0.Co;2-9  0.77
2002 Hillemeyer P, White MD, Pascual DW. Development of a transient CD4(+)CD8(+) T cell subset in the cervical lymph nodes following intratracheal instillation with an adenovirus vector. Cellular Immunology. 215: 173-85. PMID 12202154 DOI: 10.1016/S0008-8749(02)00024-2  0.444
2002 Pascual DW, Trunkle T, Sura J. Fimbriated Salmonella enterica serovar typhimurium abates initial inflammatory responses by macrophages. Infection and Immunity. 70: 4273-81. PMID 12117936 DOI: 10.1128/Iai.70.8.4273-4281.2002  0.438
2001 Pascual DW. The protective role of interleukin-18 in Salmonella infection Current Opinion in Infectious Diseases. 14: 265-271. PMID 11964842 DOI: 10.1097/00001432-200106000-00004  0.423
2001 Csencsits KL, Walters N, Pascual DW. Cutting edge: dichotomy of homing receptor dependence by mucosal effector B cells: alpha(E) versus L-selectin. Journal of Immunology (Baltimore, Md. : 1950). 167: 2441-5. PMID 11509580 DOI: 10.4049/Jimmunol.167.5.2441  0.783
2001 Wu Y, Wang X, Csencsits KL, Haddad A, Walters N, Pascual DW. M cell-targeted DNA vaccination. Proceedings of the National Academy of Sciences of the United States of America. 98: 9318-23. PMID 11459939 DOI: 10.1073/Pnas.161204098  0.797
2001 Pascual DW, White MD, Larson T, Walters N. Impaired mucosal immunity in L-selectin-deficient mice orally immunized with a Salmonella vaccine vector. Journal of Immunology (Baltimore, Md. : 1950). 167: 407-15. PMID 11418677 DOI: 10.4049/Jimmunol.167.1.407  0.508
2000 Wu Y, Boysun MJ, Csencsits KL, Pascual DW. Gene transfer facilitated by a cellular targeting molecule, reovirus protein sigma1. Gene Therapy. 7: 61-9. PMID 10680017 DOI: 10.1038/Sj.Gt.3301046  0.749
1999 Pascual DW, Hone DM, Hall S, van Ginkel FW, Yamamoto M, Walters N, Fujihashi K, Powell RJ, Wu S, Vancott JL, Kiyono H, McGhee JR. Expression of recombinant enterotoxigenic Escherichia coli colonization factor antigen I by Salmonella typhimurium elicits a biphasic T helper cell response. Infection and Immunity. 67: 6249-56. PMID 10569734 DOI: 10.1128/Iai.67.12.6249-6256.1999  0.486
1999 Dybing JK, Walters N, Pascual DW. Role of endogenous interleukin-18 in resolving wild-type and attenuated Salmonella typhimurium infections Infection and Immunity. 67: 6242-6248. PMID 10569733 DOI: 10.1128/Iai.67.12.6242-6248.1999  0.389
1999 Csencsits KL, Jutila MA, Pascual DW. Nasal-associated lymphoid tissue: phenotypic and functional evidence for the primary role of peripheral node addressin in naive lymphocyte adhesion to high endothelial venules in a mucosal site. Journal of Immunology (Baltimore, Md. : 1950). 163: 1382-9. PMID 10415038  0.772
1998 VanCott JL, Chatfield SN, Roberts M, Hone DM, Hohmann EL, Pascual DW, Yamamoto M, Kiyono H, McGhee JR. Regulation of host immune responses by modification of Salmonella virulence genes. Nature Medicine. 4: 1247-52. PMID 9809547 DOI: 10.1038/3227  0.393
1998 Ascón MA, Hone DM, Walters N, Pascual DW. Oral immunization with a Salmonella typhimurium vaccine vector expressing recombinant enterotoxigenic Escherichia coli K99 fimbriae elicits elevated antibody titers for protective immunity Infection and Immunity. 66: 5470-5476. PMID 9784559 DOI: 10.1128/Iai.66.11.5470-5476.1998  0.462
1998 Pascual DW, Walters N, Hillemeyer P. Repeated intratracheal instillations of nonreplicating adenovirus 2 vector attenuate CTL responses and IFN-γ production Journal of Immunology. 160: 4465-4472. PMID 9574552  0.307
1998 Pascual DW, Hillemeyer P. Tolerance exhibited by pulmonary CD4+ and CD8+ T cells following repeated intratracheal (i.t.) delivery of adenovirus (Ad) vector Faseb Journal. 12.  0.357
1998 Ascón MA, Hone DM, Walters N, Rognlie M, Pascual DW. Directed mucosal immunization with Salmonella vector expressing enterotoxigenic Escherichia coli (ETEC) fimbriae provokes elevated IgG and IgA responses Faseb Journal. 12: A909.  0.38
1997 Pascual DW, Coste M, Boyaka PN, Kiyono H, McGhee JR. Spontaneously hypertensive rat: cholera toxin converts suppression to immunity through a Th2 cell-IL-4 pathway. The American Journal of Physiology. 273: R1509-18. PMID 9362318 DOI: 10.1152/Ajpregu.1997.273.4.R1509  0.496
1997 Wu S, Pascual DW, Lewis GK, Hone DM. Induction of mucosal and systemic responses against human immunodeficiency virus type 1 glycoprotein 120 in mice after oral immunization with a single dose of a Salmonella-HIV vector Aids Research and Human Retroviruses. 13: 1187-1194. PMID 9310285 DOI: 10.1089/Aid.1997.13.1187  0.434
1997 van Ginkel FW, McGhee JR, Liu C, Simecka JW, Yamamoto M, Frizzell RA, Sorscher EJ, Kiyono H, Pascual DW. Adenoviral gene delivery elicits distinct pulmonary-associated T helper cell responses to the vector and to its transgene. Journal of Immunology (Baltimore, Md. : 1950). 159: 685-93. PMID 9218583  0.377
1997 Lakkis FG, Cruet EN, Nassar GM, Badr KF, Pascual DW. Expression of recombinant rat interleukin-13 (IL-13) and generation of a neutralizing rat IL-13 antiserum Biochemical and Biophysical Research Communications. 235: 529-532. PMID 9207190 DOI: 10.1006/Bbrc.1997.6832  0.357
1996 Dong JY, Wang D, Van Ginkel FW, Pascual DW, Frizzell RA. Systematic analysis of repeated gene delivery into animal lungs with a recombinant adenovirus vector Human Gene Therapy. 7: 319-331. PMID 8835219 DOI: 10.1089/Hum.1996.7.3-319  0.301
1996 Hone DM, Wu S, Powell RJ, Pascual DW, Van Cott J, McGhee J, Fouts TR, Tuskan RG, Lewis GK. Optimization of live oral Salmonella-HIV-1 vaccine vectors for the induction of HIV-specific mucosal and systemic immune responses. Journal of Biotechnology. 44: 203-7. PMID 8717405 DOI: 10.1016/0168-1656(95)00151-4  0.419
1996 VanCott JL, Staats HF, Pascual DW, Roberts M, Chatfield SN, Yamamoto M, Coste M, Carter PB, Kiyono H, McGhee JR. Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella. Journal of Immunology (Baltimore, Md. : 1950). 156: 1504-14. PMID 8568254  0.386
1996 Van Ginkel FW, Pascual DW, Liu C, Frizzell RA, Kiyono H, McGhee JR. Th1 and Th2 mediated immune responses in the respiratory tract following intranasal immunization with replication-deficient adenoviral vectors Faseb Journal. 10.  0.306
1996 Vancott JL, Chatfield SN, Hone D, Pascual DW, Hohmann E, Kivono H, McGhee JR. Immunity of attenuated salmonella vaccine vectors in ifn-y knockout (gko) mice Faseb Journal. 10: A1019.  0.388
1996 Pascual DW, Hone DM, Hall S, Van Ginkel FW, Yamamolo M, Fujihashi K, Powell RJ, Wu S, Vancott JL, Kiyono H, McGhee JR. Mode of vaccine expression by salmonella dictates th cell response: Th2 cell precedes TH1 cell antienterotoxigenic e. coli (ETEC) fimbriae responses Faseb Journal. 10: A1082.  0.472
1995 Pascual DW, Beagley KW, Kiyono H, McGhee JR. Substance P promotes Peyer's patch and splenic B cell differentiation. Advances in Experimental Medicine and Biology. 371: 55-9. PMID 8525987 DOI: 10.1007/978-1-4615-1941-6_10  0.379
1995 Wu S, Pascual DW, VanCott JL, McGhee JR, Maneval DR, Levine MM, Hone DM. Immune responses to novel Escherichia coli and Salmonella typhimurium vectors that express colonization factor antigen I (CFA/I) of enterotoxigenic E. coli in the absence of the CFA/I positive regulator cfaR. Infection and Immunity. 63: 4933-8. PMID 7591160 DOI: 10.1128/Iai.63.12.4933-4938.1995  0.395
1995 Van Ginkel FW, Liu C, Simecka JW, Dong JY, Greenway T, Frizzell RA, Kiyono H, McGhee JR, Pascual DW. Intratracheal gene delivery with adenoviral vector induces elevated systemic IgG and mucosal IgA antibodies to adenovirus and beta-galactosidase. Human Gene Therapy. 6: 895-903. PMID 7578408 DOI: 10.1089/Hum.1995.6.7-895  0.392
1994 Pascual DW, Kiyono H, McGhee JR. The enteric nervous and immune systems: interactions for mucosal immunity and inflammation. Immunomethods. 5: 56-72. PMID 7531102 DOI: 10.1006/Immu.1994.1038  0.406
1993 Pascual DW, Pascual VH, Bost KL, McGhee JR, Oparil S. Nitric oxide mediates immune dysfunction in the spontaneously hypertensive rat. Hypertension. 21: 185-94. PMID 7679089 DOI: 10.1161/01.Hyp.21.2.185  0.319
1992 Pascual VH, Oparil S, Eldridge JH, Jin H, Bost KL, Pascual DW. Spontaneously hypertensive rat: Lymphoid depression is age dependent and mediated via a mononuclear cell subpopulation American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 262. PMID 1733328 DOI: 10.1152/Ajpregu.1992.262.1.R1  0.408
1991 Pascual DW, Mcghee JR, Kiyono H, Bost KL. Neuroimmune modulation of lymphocyte function-I. Substance P enhances immunoglobulin synthesis in lipopolysaccharide activated murine splenic B cell cultures International Immunology. 3: 1223-1229. PMID 1723293 DOI: 10.1093/Intimm/3.12.1223  0.337
1988 Bost KL, Pascual DW. Antibodies against a peptide sequence within the HIV envelope protein crossreacts with human interleukin-2 Immunological Investigations. 17: 577-586. PMID 2466783 DOI: 10.3109/08820138809030591  0.316
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