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Yan-Hua Chen - Publications

Affiliations: 
East Carolina University, Greenville, NC, United States 
Area:
Cell Biology, Anatomy Biology
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Li M, Nopparat J, Aguilar BJ, Chen YH, Zhang J, Du J, Ai X, Luo Y, Jiang Y, Boykin C, Lu Q. Intratumor δ-catenin heterogeneity driven by genomic rearrangement dictates growth factor dependent prostate cancer progression. Oncogene. PMID 32313227 DOI: 10.1038/S41388-020-1281-9  0.396
2019 Xing T, Benderman LJ, Sabu S, Parker J, Yang J, Lu Q, Ding L, Chen YH. Tight junction protein claudin-7 is essential for intestinal epithelial stem cell self-renewal and differentiation. Cellular and Molecular Gastroenterology and Hepatology. PMID 31874254 DOI: 10.1016/J.Jcmgh.2019.12.005  0.351
2019 Fan J, Tatum R, Hoggard J, Chen YH. Claudin-7 Modulates Cl and Na Homeostasis and WNK4 Expression in Renal Collecting Duct Cells. International Journal of Molecular Sciences. 20. PMID 31382627 DOI: 10.3390/Ijms20153798  0.314
2019 Kim DH, Lu Q, Chen YH. Claudin-7 modulates cell-matrix adhesion that controls cell migration, invasion and attachment of human HCC827 lung cancer cells. Oncology Letters. 17: 2890-2896. PMID 30854065 DOI: 10.3892/Ol.2019.9909  0.42
2019 Aguilar BJ, Zhao Y, Zhou H, Huo S, Chen YH, Lu Q. Inhibition of Cdc42-intersectin interaction by small molecule ZCL367 impedes cancer cell cycle progression, proliferation, migration, and tumor growth. Cancer Biology & Therapy. 1-10. PMID 30849276 DOI: 10.1080/15384047.2018.1564559  0.421
2019 Li M, Nopparat J, Zhang J, Aguilar BJ, Chen Y, Du J, Ai X, Luo Y, Jiang Y, Boykin C, Lu Q. Abstract 2904: Intratumor δ-catenin heterogeneity driven by genomic rearrangement dictates growth factor dependent prostate cancer cell fate and behavior Cancer Research. 79: 2904-2904. DOI: 10.1158/1538-7445.Am2019-2904  0.406
2018 Li WJ, Xu C, Wang K, Li TY, Wang XN, Yang H, Xing T, Li WX, Chen YH, Gao H, Ding L. Severe Intestinal Inflammation in the Small Intestine of Mice Induced by Controllable Deletion of Claudin-7. Digestive Diseases and Sciences. PMID 29488037 DOI: 10.1007/S10620-018-4973-Z  0.349
2017 Kim DH, Xing T, Yang Z, Dudek R, Lu Q, Chen YH. Epithelial Mesenchymal Transition in Embryonic Development, Tissue Repair and Cancer: A Comprehensive Overview. Journal of Clinical Medicine. 7. PMID 29271928 DOI: 10.3390/Jcm7010001  0.307
2017 Xing T, Camacho Salazar R, Chen YH. Animal models for studying epithelial barriers in neonatal necrotizing enterocolitis, inflammatory bowel disease and colorectal cancer. Tissue Barriers. e1356901. PMID 28795875 DOI: 10.1080/21688370.2017.1356901  0.359
2016 Lu Q, Aguilar BJ, Li M, Jiang Y, Chen YH. Genetic alterations of δ-catenin/NPRAP/Neurojungin (CTNND2): functional implications in complex human diseases. Human Genetics. PMID 27380241 DOI: 10.1007/S00439-016-1705-3  0.319
2015 Lu Z, Kim do H, Fan J, Lu Q, Verbanac K, Ding L, Renegar R, Chen YH. A non-tight junction function of claudin-7-Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment. Molecular Cancer. 14: 120. PMID 26081244 DOI: 10.1186/S12943-015-0387-0  0.399
2014 Lu Q, Lanford GW, Hong H, Chen YH. δ-Catenin as a potential cancer biomarker. Pathology International. 64: 243-6. PMID 24888779 DOI: 10.1111/Pin.12156  0.328
2014 Lu Q, Boykin C, Zhou H, Friesland A, Chen Y. Abstract A35: Targeting Ras downstream to control motions: Rho GTPases Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-A35  0.416
2013 Lu Z, Ding L, Lu Q, Chen YH. Claudins in intestines: Distribution and functional significance in health and diseases. Tissue Barriers. 1: e24978. PMID 24478939 DOI: 10.4161/Tisb.24978  0.344
2013 Ding L, Lu Z, Lu Q, Chen YH. The claudin family of proteins in human malignancy: a clinical perspective. Cancer Management and Research. 5: 367-75. PMID 24232410 DOI: 10.2147/Cmar.S38294  0.441
2013 Hoggard J, Fan J, Lu Z, Lu Q, Sutton L, Chen YH. Claudin-7 increases chemosensitivity to cisplatin through the upregulation of caspase pathway in human NCI-H522 lung cancer cells. Cancer Science. 104: 611-8. PMID 23433123 DOI: 10.1111/Cas.12135  0.415
2013 Friesland A, Zhao Y, Chen YH, Wang L, Zhou H, Lu Q. Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility. Proceedings of the National Academy of Sciences of the United States of America. 110: 1261-6. PMID 23284167 DOI: 10.1073/Pnas.1116051110  0.371
2013 Nopparat J, Zhang J, Chen Y, Lu Q. Abstract 308: δ-Catenin/NPRAP/Neurojungin mutation promotes prostate tumorigenesis in mice overexpressing Myc oncogene . Cancer Research. 73: 308-308. DOI: 10.1158/1538-7445.Am2013-308  0.36
2012 Ding L, Lu Z, Foreman O, Tatum R, Lu Q, Renegar R, Cao J, Chen YH. Inflammation and disruption of the mucosal architecture in claudin-7-deficient mice. Gastroenterology. 142: 305-15. PMID 22044670 DOI: 10.1053/J.Gastro.2011.10.025  0.329
2012 Lu Z, Ding L, Lu Q, Chen Y. Abstract 5175: Discovering a novel role of claudin-7 as a basolateral protein maintaining cell-matrix interactions in human lung cancer cells and in mouse intestines Cancer Research. 72: 5175-5175. DOI: 10.1158/1538-7445.Am2012-5175  0.405
2011 Ding L, Zhang Y, Tatum R, Chen YH. Detection of tight junction barrier function in vivo by biotin. Methods in Molecular Biology (Clifton, N.J.). 762: 91-100. PMID 21717351 DOI: 10.1007/978-1-61779-185-7_7  0.34
2011 Lu Z, Ding L, Hong H, Hoggard J, Lu Q, Chen YH. Claudin-7 inhibits human lung cancer cell migration and invasion through ERK/MAPK signaling pathway. Experimental Cell Research. 317: 1935-46. PMID 21641901 DOI: 10.1016/J.Yexcr.2011.05.019  0.432
2011 Zhang G, Ding L, Renegar R, Wang X, Lu Q, Huo S, Chen YH. Hydroxycamptothecin-loaded Fe3O4 nanoparticles induce human lung cancer cell apoptosis through caspase-8 pathway activation and disrupt tight junctions. Cancer Science. 102: 1216-22. PMID 21435100 DOI: 10.1111/J.1349-7006.2011.01930.X  0.319
2010 Lu JP, Zhang J, Kim K, Case TC, Matusik RJ, Chen YH, Wolfe M, Nopparat J, Lu Q. Human homolog of Drosophila Hairy and enhancer of split 1, Hes1, negatively regulates δ-catenin (CTNND2) expression in cooperation with E2F1 in prostate cancer. Molecular Cancer. 9: 304. PMID 21106062 DOI: 10.1186/1476-4598-9-304  0.392
2010 Zhang J, Chen YH, Lu Q. Pro-oncogenic and anti-oncogenic pathways: opportunities and challenges of cancer therapy. Future Oncology (London, England). 6: 587-603. PMID 20373871 DOI: 10.2217/Fon.10.15  0.381
2010 Hoggard JE, Lu Z, Lu Q, Chen Y. Abstract LB-339: Claudin-7 increases chemosensitivity to cisplatin in human NCI-H522 lung cancer cells Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-339  0.418
2010 Lu Q, Boykin C, Zhang G, Chen Y, Zhang R, Fan X, Yang W. Abstract 4531: Anticancer potential of curcurbitacin IIa trough STAT3/JAK2-independent, survivin and PARP mediated apoptosis and disruption of actin cytoskeleton Cancer Research. 70: 4531-4531. DOI: 10.1158/1538-7445.Am10-4531  0.41
2009 Lu Q, Longo FM, Zhou H, Massa SM, Chen YH. Signaling through Rho GTPase pathway as viable drug target. Current Medicinal Chemistry. 16: 1355-65. PMID 19355891 DOI: 10.2174/092986709787846569  0.362
2009 Zeng Y, Abdallah A, Lu JP, Wang T, Chen YH, Terrian DM, Kim K, Lu Q. delta-Catenin promotes prostate cancer cell growth and progression by altering cell cycle and survival gene profiles. Molecular Cancer. 8: 19. PMID 19284555 DOI: 10.1186/1476-4598-8-19  0.386
2009 Wang T, Chen Y, Hong H, Zeng Y, Zhang J, Lu J, Jeansonne B, Lu Q. Increased nucleotide polymorphic changes in the 5′-untranslated region of δ-catenin (CTNND2) gene in prostate cancer Oncogene. 28: 555-564. PMID 18978817 DOI: 10.1038/Onc.2008.399  0.345
2007 Tatum R, Zhang Y, Lu Q, Kim K, Jeansonne BG, Chen YH. WNK4 phosphorylates ser(206) of claudin-7 and promotes paracellular Cl(-) permeability. Febs Letters. 581: 3887-91. PMID 17651736 DOI: 10.1016/J.Febslet.2007.07.014  0.305
2005 Lu Q, Dobbs LJ, Gregory CW, Lanford GW, Revelo MP, Shappell S, Chen YH. Increased expression of delta-catenin/neural plakophilin-related armadillo protein is associated with the down-regulation and redistribution of E-cadherin and p120ctn in human prostate cancer. Human Pathology. 36: 1037-48. PMID 16226102 DOI: 10.1016/J.Humpath.2005.07.012  0.402
2005 Alexandre MD, Lu Q, Chen YH. Overexpression of claudin-7 decreases the paracellular Cl- conductance and increases the paracellular Na+ conductance in LLC-PK1 cells. Journal of Cell Science. 118: 2683-93. PMID 15928046 DOI: 10.1242/Jcs.02406  0.363
2002 Chen YH, Lu Q, Goodenough DA, Jeansonne B. Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells. Molecular Biology of the Cell. 13: 1227-37. PMID 11950934 DOI: 10.1091/Mbc.01-08-0423  0.315
2000 Chen Yh, Lu Q, Schneeberger EE, Goodenough DA. Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells. Molecular Biology of the Cell. 11: 849-62. PMID 10712504 DOI: 10.1091/Mbc.11.3.849  0.386
1998 Merzdorf CS, Chen YH, Goodenough DA. Formation of functional tight junctions in Xenopus embryos. Developmental Biology. 195: 187-203. PMID 9520334 DOI: 10.1006/Dbio.1997.8846  0.305
1997 Chen Y, Merzdorf C, Paul DL, Goodenough DA. COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos. The Journal of Cell Biology. 138: 891-9. PMID 9265654 DOI: 10.1083/Jcb.138.4.891  0.327
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