Year |
Citation |
Score |
2024 |
Iwanski JB, Pappas CT, Mayfield RM, Farman GP, Ahrens-Nicklas R, Churko JM, Gregorio CC. Leiomodin 2 neonatal dilated cardiomyopathy mutation results in altered actin gene signatures and cardiomyocyte dysfunction. Npj Regenerative Medicine. 9: 21. PMID 39285234 DOI: 10.1038/s41536-024-00366-y |
0.395 |
|
2024 |
Larrinaga TM, Farman GP, Mayfield RM, Yuen M, Ahrens-Nicklas RC, Cooper ST, Pappas CT, Gregorio CC. Lmod2 is necessary for effective skeletal muscle contraction. Science Advances. 10: eadk1890. PMID 38478604 DOI: 10.1126/sciadv.adk1890 |
0.421 |
|
2024 |
Vasilescu C, Colpan M, Ojala TH, Manninen T, Mutka A, Ylänen K, Rahkonen O, Poutanen T, Martelius L, Kumari R, Hinterding H, Brilhante V, Ojanen S, Lappalainen P, Koskenvuo J, ... ... Gregorio CC, et al. Recessive TMOD1 mutation causes childhood cardiomyopathy. Communications Biology. 7: 7. PMID 38168645 DOI: 10.1038/s42003-023-05670-9 |
0.66 |
|
2023 |
Schultz LE, Colpan M, Smith GE, Mayfield RM, Larrinaga TM, Kostyukova AS, Gregorio CC. A nemaline myopathy-linked mutation inhibits the actin-regulatory functions of tropomodulin and leiomodin. Proceedings of the National Academy of Sciences of the United States of America. 120: e2315820120. PMID 37956287 DOI: 10.1073/pnas.2315820120 |
0.49 |
|
2023 |
Sono R, Larrinaga TM, Huang A, Makhlouf F, Kang X, Su J, Lau R, Arboleda VA, Biniwale R, Fishbein GA, Khanlou N, Si MS, Satou GM, Halnon N, Van Arsdell GS, ... Gregorio CC, et al. Whole-Exome Sequencing Identifies Homozygote Nonsense Variants in Gene Causing Infantile Dilated Cardiomyopathy. Cells. 12. PMID 37296576 DOI: 10.3390/cells12111455 |
0.409 |
|
2022 |
Smith GE, Tolkatchev D, Risi C, Little M, Gregorio CC, Galkin VE, Kostyukova AS. Ca attenuates nucleation activity of leiomodin. Protein Science : a Publication of the Protein Society. 31: e4358. PMID 35762710 DOI: 10.1002/pro.4358 |
0.307 |
|
2021 |
Iwanski J, Gregorio CC, Colpan M. Redefining actin dynamics of the pointed-end complex in striated muscle. Trends in Cell Biology. PMID 34266732 DOI: 10.1016/j.tcb.2021.06.006 |
0.408 |
|
2021 |
Colpan M, Iwanski J, Gregorio CC. CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle. Communications Biology. 4: 365. PMID 33742108 DOI: 10.1038/s42003-021-01893-w |
0.568 |
|
2020 |
Kiss B, Gohlke J, Tonino P, Hourani Z, Kolb J, Strom J, Alekhina O, Smith JE, Ottenheijm C, Gregorio C, Granzier H. Nebulin and Lmod2 are critical for specifying thin-filament length in skeletal muscle. Science Advances. 6. PMID 33177085 DOI: 10.1126/sciadv.abc1992 |
0.467 |
|
2020 |
Tolkatchev D, Smith GE, Schultz LE, Colpan M, Helms GL, Cort JR, Gregorio CC, Kostyukova AS. Leiomodin creates a leaky cap at the pointed end of actin-thin filaments. Plos Biology. 18: e3000848. PMID 32898131 DOI: 10.1371/Journal.Pbio.3000848 |
0.571 |
|
2020 |
Mi-Mi L, Farman GP, Mayfield RM, Strom J, Chu M, Pappas CT, Gregorio CC. In vivo elongation of thin filaments results in heart failure. Plos One. 15: e0226138. PMID 31899774 DOI: 10.1371/Journal.Pone.0226138 |
0.46 |
|
2019 |
Rudolph F, Hüttemeister J, da Silva Lopes K, Jüttner R, Yu L, Bergmann N, Friedrich D, Preibisch S, Wagner E, Lehnart SE, Gregorio CC, Gotthardt M. Resolving titin's lifecycle and the spatial organization of protein turnover in mouse cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31757849 DOI: 10.1073/Pnas.1904385116 |
0.436 |
|
2019 |
Ahrens-Nicklas RC, Pappas CT, Farman GP, Mayfield RM, Larrinaga TM, Medne L, Ritter A, Krantz ID, Murali C, Lin KY, Berger JH, Yum SW, Carreon CK, Gregorio CC. Disruption of cardiac thin filament assembly arising from a mutation in : A novel mechanism of neonatal dilated cardiomyopathy. Science Advances. 5: eaax2066. PMID 31517052 DOI: 10.1126/Sciadv.Aax2066 |
0.509 |
|
2019 |
Yuen M, Schultz L, Mayfield R, Shen S, Conijn S, Winter Jd, Bogaards S, Pijl Rvd, Meskovic M, Vries ID, Granzier H, Gregorio C, Ottenheijm C. O.34Leiomodin-3 (LMOD3) deficiency affects contractile function and structure of fast muscle fibres Neuromuscular Disorders. 29. DOI: 10.1016/J.Nmd.2019.06.317 |
0.366 |
|
2018 |
Ly T, Pappas CT, Johnson D, Schlecht W, Colpan M, Galkin VE, Gregorio CC, Dong WJ, Kostyukova AS. Effects of cardiomyopathy-linked mutations k15n and r21h in tropomyosin on thin filament regulation and pointed-end dynamics. Molecular Biology of the Cell. mbcE18060406. PMID 30462572 DOI: 10.1091/Mbc.E18-06-0406 |
0.438 |
|
2018 |
Pappas CT, Farman GP, Mayfield RM, Konhilas JP, Gregorio CC. Cardiac-specific knockout of Lmod2 results in a severe reduction in myofilament force production and rapid cardiac failure. Journal of Molecular and Cellular Cardiology. PMID 30102883 DOI: 10.1016/J.Yjmcc.2018.08.009 |
0.487 |
|
2018 |
Trembley MA, Quijada P, Agullo-Pascual E, Tylock KM, Colpan M, Dirkx RA, Myers JR, Mickelsen DM, de Mesy Bentley K, Rothenberg E, Moravec CS, Alexis JD, Gregorio CC, Dirksen RT, Delmar M, et al. Mechanosensitive Gene Regulation by Myocardin-Related Transcription Factors is Required for Cardiomyocyte Integrity in Load-Induced Ventricular Hypertrophy. Circulation. PMID 29716942 DOI: 10.1161/Circulationaha.117.031788 |
0.425 |
|
2018 |
Jamilpour N, Nam K, Gregorio CC, Wong PK. Probing Collective Mechanoadaptation in Cardiomyocyte Development by Plasma Lithography Patterned Elastomeric Substrates Acs Biomaterials Science & Engineering. 5: 3808-3816. DOI: 10.1021/Acsbiomaterials.8B00815 |
0.317 |
|
2017 |
Sun X, Hota SK, Zhou YQ, Novak S, Miguel-Perez D, Christodoulou D, Seidman CE, Seidman JG, Gregorio CC, Henkelman RM, Rossant J, Bruneau BG. Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function. Biology Open. PMID 29183906 DOI: 10.1242/Bio.029512 |
0.387 |
|
2017 |
Chu M, Novak SM, Cover C, Wang AA, Chinyere IR, Juneman E, Zarnescu DC, Wong PK, Gregorio C. Increased Cardiac Arrhythmogenesis Associated with Gap Junction Remodeling with Upregulation of RNA Binding Protein FXR1. Circulation. PMID 29101288 DOI: 10.1161/Circulationaha.117.028976 |
0.456 |
|
2017 |
Wu T, Mu Y, Bogomolovas J, Fang X, Veevers J, Nowak RB, Pappas CT, Gregorio CC, Evans SM, Fowler VM, Chen J. HSPB7 is indispensable for heart development by modulating actin filament assembly. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078393 DOI: 10.1073/Pnas.1713763114 |
0.743 |
|
2017 |
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC. Overview of the Muscle Cytoskeleton. Comprehensive Physiology. 7: 891-944. PMID 28640448 DOI: 10.1002/Cphy.C160033 |
0.528 |
|
2017 |
Gotthardt M, Rudolph F, Huettemeister J, da Sliva Lopes K, Yu L, Bergmann N, Fink C, Wagner E, Lehnart S, Gregorio C. From Ribosome to Sarcomere - Titin Dynamics in Striated Muscle Cells Biophysical Journal. 112: 429a. DOI: 10.1016/J.Bpj.2016.11.2293 |
0.514 |
|
2016 |
Ly T, Moroz N, Pappas CT, Novak SM, Tolkatchev D, Wooldridge D, Mayfield RM, Helms G, Gregorio CC, Kostyukova AS. The N-terminal tropomyosin- and actin-binding sites are important for leiomodin 2's function. Molecular Biology of the Cell. PMID 27307584 DOI: 10.1091/Mbc.E16-03-0200 |
0.505 |
|
2016 |
de Winter JM, Joureau B, Lee EJ, Kiss B, Yuen M, Gupta VA, Pappas CT, Gregorio CC, Stienen GJ, Edvardson S, Wallgren-Pettersson C, Lehtokari VL, Pelin K, Malfatti E, Romero NB, et al. Mutation-specific effects on thin filament length in thin filament myopathy. Annals of Neurology. PMID 27074222 DOI: 10.1002/Ana.24654 |
0.509 |
|
2016 |
Behunin SM, Lopez-Pier MA, Mayfield RM, Danilo CA, Lipovka Y, Birch C, Lehman S, Tardiff JC, Gregorio CC, Konhilas JP. Liver Kinase B 1 Complex Acts as a Novel Modifier of Myofilament Function and Localizes to the Z-Disk in Cardiac Myocytes. Archives of Biochemistry and Biophysics. PMID 26971467 DOI: 10.1016/J.Abb.2016.03.012 |
0.398 |
|
2016 |
Chu M, Gregorio CC, Pappas CT. Nebulin, a multi-functional giant. The Journal of Experimental Biology. 219: 146-52. PMID 26792324 DOI: 10.1242/Jeb.126383 |
0.602 |
|
2015 |
Novak SM, Joardar A, Gregorio CC, Zarnescu DC. Regulation of Heart Rate in Drosophila via Fragile X Mental Retardation Protein. Plos One. 10: e0142836. PMID 26571124 DOI: 10.1371/Journal.Pone.0142836 |
0.496 |
|
2015 |
Pappas CT, Mayfield RM, Henderson C, Jamilpour N, Cover C, Hernandez Z, Hutchinson KR, Chu M, Nam KH, Valdez JM, Wong PK, Granzier HL, Gregorio CC. Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality. Proceedings of the National Academy of Sciences of the United States of America. 112: 13573-8. PMID 26487682 DOI: 10.1073/Pnas.1508273112 |
0.576 |
|
2015 |
Yuen M, Sandaradura SA, Dowling JJ, Kostyukova AS, Moroz N, Quinlan KG, Lehtokari VL, Ravenscroft G, Todd EJ, Ceyhan-Birsoy O, Gokhin DS, Maluenda J, Lek M, Nolent F, Pappas CT, ... ... Gregorio CC, et al. Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy. The Journal of Clinical Investigation. 125: 456-7. PMID 25654555 DOI: 10.1172/Jci80057 |
0.685 |
|
2015 |
Nworu CU, Kraft R, Schnurr DC, Gregorio CC, Krieg PA. Leiomodin 3 and tropomodulin 4 have overlapping functions during skeletal myofibrillogenesis. Journal of Cell Science. 128: 239-50. PMID 25431137 DOI: 10.1242/Jcs.152702 |
0.82 |
|
2015 |
Joureau B, de Winter J, Pappas CT, Malfatti E, Beggs A, Clarke N, Romero N, Gregorio C, Granzier H, Stienen GJ, Ottenheijm CC. Force-Sarcomere Length Relations in Patients with Thin Filament Myopathy Caused by Mutations in NEB, ACTA1, TPM2, TPM3, KBTBD13, KLHL40 and KLHL41 Biophysical Journal. 108: 338a-339a. DOI: 10.1016/J.Bpj.2014.11.1847 |
0.375 |
|
2015 |
Henderson CA, Gregorio CC. Dynamics of actin in the heart: Defining thin filament length Cardiac Cytoarchitecture: How to Maintain a Working Heart. 71-88. DOI: 10.1007/978-3-319-15263-9_4 |
0.531 |
|
2014 |
Ono Y, Shindo M, Doi N, Kitamura F, Gregorio CC, Sorimachi H. The N- and C-terminal autolytic fragments of CAPN3/p94/calpain-3 restore proteolytic activity by intermolecular complementation. Proceedings of the National Academy of Sciences of the United States of America. 111: E5527-36. PMID 25512505 DOI: 10.1073/Pnas.1411959111 |
0.373 |
|
2014 |
Yuen M, Sandaradura SA, Dowling JJ, Kostyukova AS, Moroz N, Quinlan KG, Lehtokari VL, Ravenscroft G, Todd EJ, Ceyhan-Birsoy O, Gokhin DS, Maluenda J, Lek M, Nolent F, Pappas CT, ... ... Gregorio CC, et al. Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy. The Journal of Clinical Investigation. 124: 4693-708. PMID 25250574 DOI: 10.1172/Jci75199 |
0.712 |
|
2014 |
Granzier HL, Hutchinson KR, Tonino P, Methawasin M, Li FW, Slater RE, Bull MM, Saripalli C, Pappas CT, Gregorio CC, Smith JE. Deleting titin's I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function. Proceedings of the National Academy of Sciences of the United States of America. 111: 14589-94. PMID 25246556 DOI: 10.1073/Pnas.1411493111 |
0.459 |
|
2014 |
Bliss KT, Tsukada T, Novak SM, Dorovkov MV, Shah SP, Nworu C, Kostyukova AS, Gregorio CC. Phosphorylation of tropomodulin1 contributes to the regulation of actin filament architecture in cardiac muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 3987-95. PMID 24891520 DOI: 10.1096/Fj.13-246009 |
0.753 |
|
2014 |
Nworu CU, Krieg PA, Gregorio CC. Preparation of developing Xenopus muscle for sarcomeric protein localization by high-resolution imaging. Methods (San Diego, Calif.). 66: 370-9. PMID 23806641 DOI: 10.1016/J.Ymeth.2013.06.015 |
0.778 |
|
2013 |
Ono Y, Iemura S, Novak SM, Doi N, Kitamura F, Natsume T, Gregorio CC, Sorimachi H. PLEIAD/SIMC1/C5orf25, a novel autolysis regulator for a skeletal-muscle-specific calpain, CAPN3, scaffolds a CAPN3 substrate, CTBP1. Journal of Molecular Biology. 425: 2955-72. PMID 23707407 DOI: 10.1016/J.Jmb.2013.05.009 |
0.508 |
|
2013 |
Zarnescu DC, Gregorio CC. Fragile hearts: new insights into translational control in cardiac muscle. Trends in Cardiovascular Medicine. 23: 275-81. PMID 23582851 DOI: 10.1016/J.Tcm.2013.03.003 |
0.438 |
|
2013 |
Bliss KT, Chu M, Jones-Weinert CM, Gregorio CC. Investigating lasp-2 in cell adhesion: new binding partners and roles in motility. Molecular Biology of the Cell. 24: 995-1006. PMID 23389630 DOI: 10.1091/Mbc.E12-10-0723 |
0.768 |
|
2013 |
Moroz NA, Novak SM, Azevedo R, Colpan M, Uversky VN, Gregorio CC, Kostyukova AS. Alteration of tropomyosin-binding properties of tropomodulin-1 affects its capping ability and localization in skeletal myocytes. The Journal of Biological Chemistry. 288: 4899-907. PMID 23271735 DOI: 10.1074/Jbc.M112.434522 |
0.535 |
|
2012 |
Raskin A, Lange S, Banares K, Lyon RC, Zieseniss A, Lee LK, Yamazaki KG, Granzier HL, Gregorio CC, McCulloch AD, Omens JH, Sheikh F. A novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics. The Journal of Biological Chemistry. 287: 29273-84. PMID 22778266 DOI: 10.1074/Jbc.M112.372839 |
0.5 |
|
2012 |
Leinwand LA, Tardiff JC, Gregorio CC. Mutations in the sensitive giant titin result in a broken heart. Circulation Research. 111: 158-61. PMID 22773424 DOI: 10.1161/Res.0B013E3182635Ca2 |
0.517 |
|
2012 |
Warkman AS, Whitman SA, Miller MK, Garriock RJ, Schwach CM, Gregorio CC, Krieg PA. Developmental expression and cardiac transcriptional regulation of Myh7b, a third myosin heavy chain in the vertebrate heart. Cytoskeleton (Hoboken, N.J.). 69: 324-35. PMID 22422726 DOI: 10.1002/Cm.21029 |
0.75 |
|
2012 |
Donlin LT, Andresen C, Just S, Rudensky E, Pappas CT, Kruger M, Jacobs EY, Unger A, Zieseniss A, Dobenecker MW, Voelkel T, Chait BT, Gregorio CC, Rottbauer W, Tarakhovsky A, et al. Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization. Genes & Development. 26: 114-9. PMID 22241783 DOI: 10.1101/Gad.177758.111 |
0.376 |
|
2012 |
Warkman AS, Whitman SA, Miller MK, Garriock RJ, Schwach CM, Gregorio CC, Krieg PA. Correction: Developmental expression and cardiac transcriptional regulation of Myh7b, a third myosin heavy chain in the vertebrate heart Cytoskeleton. 69: 1086-1086. DOI: 10.1002/cm.21089 |
0.72 |
|
2011 |
Junkin M, Leung SL, Whitman S, Gregorio CC, Wong PK. Cellular self-organization by autocatalytic alignment feedback. Journal of Cell Science. 124: 4213-20. PMID 22193956 DOI: 10.1242/Jcs.088898 |
0.735 |
|
2011 |
Conover GM, Gregorio CC. The desmin coil 1B mutation K190A impairs nebulin Z-disc assembly and destabilizes actin thin filaments. Journal of Cell Science. 124: 3464-76. PMID 21984811 DOI: 10.1242/Jcs.087080 |
0.572 |
|
2011 |
Whitman SA, Cover C, Yu L, Nelson DL, Zarnescu DC, Gregorio CC. Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle. Circulation Research. 109: 262-71. PMID 21659647 DOI: 10.1161/Circresaha.111.244244 |
0.78 |
|
2011 |
Tsukada T, Kotlyanskaya L, Huynh R, Desai B, Novak SM, Kajava AV, Gregorio CC, Kostyukova AS. Identification of residues within tropomodulin-1 responsible for its localization at the pointed ends of the actin filaments in cardiac myocytes. The Journal of Biological Chemistry. 286: 2194-204. PMID 21078668 DOI: 10.1074/Jbc.M110.186924 |
0.447 |
|
2011 |
Pappas CT, Bliss KT, Zieseniss A, Gregorio CC. The Nebulin family: an actin support group. Trends in Cell Biology. 21: 29-37. PMID 20951588 DOI: 10.1016/J.Tcb.2010.09.005 |
0.806 |
|
2011 |
Pappas CT, Krieg PA, Gregorio C. Deciphering the Functional Properties of Nebulin: It is a Stabilizer! Biophysical Journal. 100: 588a. DOI: 10.1016/J.Bpj.2010.12.3396 |
0.601 |
|
2010 |
Tsukada T, Pappas CT, Moroz N, Antin PB, Kostyukova AS, Gregorio CC. Leiomodin-2 is an antagonist of tropomodulin-1 at the pointed end of the thin filaments in cardiac muscle. Journal of Cell Science. 123: 3136-45. PMID 20736303 DOI: 10.1242/Jcs.071837 |
0.621 |
|
2010 |
Pappas CT, Krieg PA, Gregorio CC. Nebulin regulates actin filament lengths by a stabilization mechanism. The Journal of Cell Biology. 189: 859-70. PMID 20498015 DOI: 10.1085/Jgp1361Oia1 |
0.581 |
|
2010 |
Tonino P, Pappas CT, Hudson BD, Labeit S, Gregorio CC, Granzier H. Reduced myofibrillar connectivity and increased Z-disk width in nebulin-deficient skeletal muscle. Journal of Cell Science. 123: 384-91. PMID 20053633 DOI: 10.1242/Jcs.042234 |
0.415 |
|
2010 |
Tsukada T, Kotlyanskaya L, Gregorio CC, Kostyukova AS. LRR Domain of Tropomodulin is Responsible for Targeting it to the Pointed End of the Actin Filament Biophysical Journal. 98: 157a. DOI: 10.1016/J.Bpj.2009.12.842 |
0.508 |
|
2009 |
Conover GM, Henderson SN, Gregorio CC. A myopathy-linked desmin mutation perturbs striated muscle actin filament architecture. Molecular Biology of the Cell. 20: 834-45. PMID 19005210 DOI: 10.1091/Mbc.E08-07-0753 |
0.511 |
|
2008 |
Moran CM, Garriock RJ, Miller MK, Heimark RL, Gregorio CC, Krieg PA. Expression of the fast twitch troponin complex, fTnT, fTnI and fTnC, in vascular smooth muscle. Cell Motility and the Cytoskeleton. 65: 652-61. PMID 18548613 DOI: 10.1002/Cm.20291 |
0.456 |
|
2008 |
Pappas CT, Bhattacharya N, Cooper JA, Gregorio CC. Nebulin interacts with CapZ and regulates thin filament architecture within the Z-disc. Molecular Biology of the Cell. 19: 1837-47. PMID 18272787 DOI: 10.1091/Mbc.E07-07-0690 |
0.551 |
|
2008 |
Zieseniss A, Terasaki AG, Gregorio CC. Lasp-2 expression, localization, and ligand interactions: a new Z-disc scaffolding protein. Cell Motility and the Cytoskeleton. 65: 59-72. PMID 17968983 DOI: 10.1002/Cm.20244 |
0.595 |
|
2005 |
Gregorio CC, Perry CN, McElhinny AS. Functional properties of the titin/connectin-associated proteins, the muscle-specific RING finger proteins (MURFs), in striated muscle. Journal of Muscle Research and Cell Motility. 26: 389-400. PMID 16477476 DOI: 10.1007/S10974-005-9021-X |
0.539 |
|
2005 |
McElhinny AS, Schwach C, Valichnac M, Mount-Patrick S, Gregorio CC. Nebulin regulates the assembly and lengths of the thin filaments in striated muscle. The Journal of Cell Biology. 170: 947-57. PMID 16157704 DOI: 10.1083/Jcb.200502158 |
0.602 |
|
2005 |
Ono Y, Schwach C, Antin PB, Gregorio CC. Disruption in the tropomodulin1 (Tmod1) gene compromises cardiomyocyte development in murine embryonic stem cells by arresting myofibril maturation. Developmental Biology. 282: 336-48. PMID 15950601 DOI: 10.1016/J.Ydbio.2005.03.015 |
0.511 |
|
2005 |
Adameyko II, Mudry RE, Houston-Cummings NR, Veselov AP, Gregorio CC, Tevosian SG. Expression and regulation of mouse SERDIN1, a highly conserved cardiac-specific leucine-rich repeat protein. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 233: 540-52. PMID 15830381 DOI: 10.1002/Dvdy.20368 |
0.417 |
|
2004 |
McElhinny AS, Perry CN, Witt CC, Labeit S, Gregorio CC. Muscle-specific RING finger-2 (MURF-2) is important for microtubule, intermediate filament and sarcomeric M-line maintenance in striated muscle development. Journal of Cell Science. 117: 3175-88. PMID 15199100 DOI: 10.1242/Jcs.01158 |
0.557 |
|
2004 |
Miller MK, Granzier H, Ehler E, Gregorio CC. The sensitive giant: the role of titin-based stretch sensing complexes in the heart. Trends in Cell Biology. 14: 119-26. PMID 15003620 DOI: 10.1016/J.Tcb.2004.01.003 |
0.403 |
|
2004 |
Witt CC, Ono Y, Puschmann E, McNabb M, Wu Y, Gotthardt M, Witt SH, Haak M, Labeit D, Gregorio CC, Sorimachi H, Granzier H, Labeit S. Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling. Journal of Molecular Biology. 336: 145-54. PMID 14741210 DOI: 10.1016/J.Jmb.2003.12.021 |
0.485 |
|
2003 |
Fritz-Six KL, Cox PR, Fischer RS, Xu B, Gregorio CC, Zoghbi HY, Fowler VM. Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality. The Journal of Cell Biology. 163: 1033-44. PMID 14657235 DOI: 10.1083/Jcb.200308164 |
0.711 |
|
2003 |
Miller MK, Bang ML, Witt CC, Labeit D, Trombitas C, Watanabe K, Granzier H, McElhinny AS, Gregorio CC, Labeit S. The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules. Journal of Molecular Biology. 333: 951-64. PMID 14583192 DOI: 10.1016/J.Jmb.2003.09.012 |
0.491 |
|
2003 |
Mudry RE, Perry CN, Richards M, Fowler VM, Gregorio CC. The interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes. The Journal of Cell Biology. 162: 1057-68. PMID 12975349 DOI: 10.1083/Jcb.200305031 |
0.74 |
|
2003 |
McElhinny AS, Kazmierski ST, Labeit S, Gregorio CC. Nebulin: the nebulous, multifunctional giant of striated muscle. Trends in Cardiovascular Medicine. 13: 195-201. PMID 12837582 DOI: 10.1016/S1050-1738(03)00076-8 |
0.561 |
|
2003 |
Kazmierski ST, Antin PB, Witt CC, Huebner N, McElhinny AS, Labeit S, Gregorio CC. The complete mouse nebulin gene sequence and the identification of cardiac nebulin. Journal of Molecular Biology. 328: 835-46. PMID 12729758 DOI: 10.1016/S0022-2836(03)00348-6 |
0.586 |
|
2002 |
Knöll R, Hoshijima M, Hoffman HM, Person V, Lorenzen-Schmidt I, Bang ML, Hayashi T, Shiga N, Yasukawa H, Schaper W, McKenna W, Yokoyama M, Schork NJ, Omens JH, McCulloch AD, ... ... Gregorio CC, et al. The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. Cell. 111: 943-55. PMID 12507422 DOI: 10.1016/S0092-8674(02)01226-6 |
0.472 |
|
2002 |
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC. Striated muscle cytoarchitecture: an intricate web of form and function. Annual Review of Cell and Developmental Biology. 18: 637-706. PMID 12142273 DOI: 10.1146/Annurev.Cellbio.18.012502.105840 |
0.494 |
|
2002 |
Bang ML, Gregorio C, Labeit S. Molecular dissection of the interaction of desmin with the C-terminal region of nebulin. Journal of Structural Biology. 137: 119-27. PMID 12064939 DOI: 10.1006/Jsbi.2002.4457 |
0.345 |
|
2002 |
McElhinny AS, Kakinuma K, Sorimachi H, Labeit S, Gregorio CC. Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1. The Journal of Cell Biology. 157: 125-36. PMID 11927605 DOI: 10.1083/Jcb.200108089 |
0.463 |
|
2001 |
Bang ML, Centner T, Fornoff F, Geach AJ, Gotthardt M, McNabb M, Witt CC, Labeit D, Gregorio CC, Granzier H, Labeit S. The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system. Circulation Research. 89: 1065-72. PMID 11717165 DOI: 10.1161/Hh2301.100981 |
0.432 |
|
2001 |
Furukawa T, Ono Y, Tsuchiya H, Katayama Y, Bang ML, Labeit D, Labeit S, Inagaki N, Gregorio CC. Specific interaction of the potassium channel β-subunit minK with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system Journal of Molecular Biology. 313: 775-784. PMID 11697903 DOI: 10.1006/Jmbi.2001.5053 |
0.392 |
|
2001 |
Rudy DE, Yatskievych TA, Antin PB, Gregorio CC. Assembly of thick, thin, and titin filaments in chick precardiac explants. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 221: 61-71. PMID 11357194 DOI: 10.1002/Dvdy.1125 |
0.803 |
|
2001 |
Bang ML, Mudry RE, McElhinny AS, Trombitás K, Geach AJ, Yamasaki R, Sorimachi H, Granzier H, Gregorio CC, Labeit S. Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies Journal of Cell Biology. 153: 413-427. PMID 11309420 DOI: 10.1083/Jcb.153.2.413 |
0.529 |
|
2001 |
Centner T, Yano J, Kimura E, McElhinny AS, Pelin K, Witt CC, Bang ML, Trombitas K, Granzier H, Gregorio CC, Sorimachi H, Labeit S. Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain. Journal of Molecular Biology. 306: 717-26. PMID 11243782 DOI: 10.1006/Jmbi.2001.4448 |
0.444 |
|
2001 |
McElhinny AS, Kolmerer B, Fowler VM, Labeit S, Gregorio CC. The N-terminal end of nebulin interacts with tropomodulin at the pointed ends of the thin filaments Journal of Biological Chemistry. 276: 583-592. PMID 11016930 DOI: 10.1074/Jbc.M005693200 |
0.738 |
|
2000 |
McElhinny AS, Labeit S, Gregorio CC, Sanger, TerKeurs. Probing the functional roles of titin ligands in cardiac myofibril assembly and maintenance Advances in Experimental Medicine and Biology. 481: 67-88. PMID 10987067 DOI: 10.1007/978-1-4615-4267-4_5 |
0.528 |
|
2000 |
Centner T, Fougerousse F, Freiburg A, Witt C, Beckmann JS, Granzier H, Trombitás K, Gregorio CC, Labeit S, Greaser, Bullard, Linke, Pollack, Trinick. Molecular tools for the study of titin's differential expression Advances in Experimental Medicine and Biology. 481: 35-52. PMID 10987065 DOI: 10.1007/978-1-4615-4267-4_3 |
0.358 |
|
2000 |
Gregorio CC, Antin PB. To the heart of myofibril assembly. Trends in Cell Biology. 10: 355-62. PMID 10932092 DOI: 10.1016/S0962-8924(00)01793-1 |
0.56 |
|
2000 |
Freiburg A, Trombitas K, Hell W, Cazorla O, Fougerousse F, Centner T, Kolmerer B, Witt C, Beckmann JS, Gregorio CC, Granzier H, Labeit S. Series of exon-skipping events in the elastic spring region of titin as the structural basis for myofibrillar elastic diversity Circulation Research. 86: 1114-1121. PMID 10850961 DOI: 10.1161/01.Res.86.11.1114 |
0.474 |
|
1999 |
Linke WA, Rudy DE, Centner T, Gautel M, Witt C, Labeit S, Gregorio CC. I-band titin in cardiac muscle is a three-element molecular spring and is critical for maintaining thin filament structure. The Journal of Cell Biology. 146: 631-44. PMID 10444071 DOI: 10.1083/Jcb.146.3.631 |
0.762 |
|
1999 |
Almenar-Queralt A, Gregorio CC, Fowler VM. Tropomodulin assembles early in myofibrillogenesis in chick skeletal muscle: Evidence that thin filaments rearrange to form striated myofibrils Journal of Cell Science. 112: 1111-1123. PMID 10085247 |
0.725 |
|
1999 |
Gregorio CC, Granzier H, Sorimachi H, Labeit S. Muscle assembly: A titanic achievement? Current Opinion in Cell Biology. 11: 18-25. PMID 10047523 DOI: 10.1016/S0955-0674(99)80003-9 |
0.519 |
|
1998 |
Gregorio CC, Trombitás K, Centner T, Kolmerer B, Stier G, Kunke K, Suzuki K, Obermayr F, Herrmann B, Granzier H, Sorimachi H, Labeit S. The NH2 terminus of titin spans the Z-disc: its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity. The Journal of Cell Biology. 143: 1013-27. PMID 9817758 DOI: 10.1083/Jcb.143.4.1013 |
0.418 |
|
1997 |
Sorimachi H, Freiburg A, Kolmerer B, Ishiura S, Stier G, Gregorio CC, Labeit D, Linke WA, Suzuki K, Labeit S. Tissue-specific expression and α-actinin binding properties of the Z-disc titin: Implications for the nature of vertebrate Z-discs Journal of Molecular Biology. 270: 688-695. PMID 9245597 DOI: 10.1006/Jmbi.1997.1145 |
0.434 |
|
1997 |
Gregorio CC. Models of thin filament assembly in cardiac and skeletal muscle Cell Structure and Function. 22: 191-195. PMID 9113406 DOI: 10.1247/Csf.22.191 |
0.582 |
|
1996 |
Gregorio CC, Fowler VM. Tropomodulin function and thin filament assembly in cardiac myocytes Trends in Cardiovascular Medicine. 6: 136-141. DOI: 10.1016/1050-1738(96)00022-9 |
0.775 |
|
1995 |
Gregorio CC, Fowler VM. Mechanisms of thin filament assembly in embryonic chick cardiac myocytes: Tropomodulin requires tropomyosin for assembly Journal of Cell Biology. 129: 683-695. PMID 7730404 DOI: 10.1083/Jcb.129.3.683 |
0.73 |
|
1995 |
Gregorio CC, Weber A, Bondad M, Pennise CR, Fowler VM. Requirement of pointed-end capping by tropomodulin to maintain actin filament length in embryonic chick cardiac myocytes. Nature. 377: 83-6. PMID 7544875 DOI: 10.1038/377083A0 |
0.756 |
|
1994 |
Gregorio CC, Repasky EA, Fowler VM, Black JD. Dynamic properties of ankyrin in T lymphocytes: Colocalization with spectrin and protein kinase Cβ Journal of Cell Biology. 125: 345-358. PMID 8163551 DOI: 10.1083/Jcb.125.2.345 |
0.578 |
|
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