Chester Eng, Ph.D. - Publications

Affiliations: 
2002 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Astronomy and Astrophysics

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Year Citation  Score
2021 Kim SJ, Lubiński J, Huzarski T, Møller P, Armel S, Karlan BY, Senter L, Eisen A, Foulkes WD, Singer CF, Tung N, Bordeleau L, Neuhausen SL, Olopade OI, Eng C, et al. Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 34426412 DOI: 10.1158/1055-9965.EPI-21-0296  1
2021 Uljarević M, Frazier TW, Rached G, Busch RM, Klaas P, Srivastava S, Martinez-Agosto JA, Sahin M, Eng C, Hardan AY. Toward better characterization of restricted and repetitive behaviors in individuals with germline heterozygous PTEN mutations. American Journal of Medical Genetics. Part A. PMID 34423884 DOI: 10.1002/ajmg.a.62458  1
2021 Khare A, Burke CA, Heald B, O'Malley M, LaGuardia L, Milicia S, Cruise M, Eng C, Mankaney G. Endoscopic Findings in Patients With PTEN Hamartoma Tumor Syndrome Undergoing Surveillance. Journal of Clinical Gastroenterology. PMID 34231499 DOI: 10.1097/MCG.0000000000001580  1
2021 Grencewicz DJ, Romigh T, Thacker S, Abbas A, Jaini R, Luse D, Eng C. Redefining the PTEN promoter: Identification of novel upstream transcription start regions. Human Molecular Genetics. PMID 34218272 DOI: 10.1093/hmg/ddab175  1
2021 Doherty C, Kinzy TG, Ferguson L, Altemus J, Hermann BP, Eng C, Najm I, Busch RM. The role of genetic polymorphisms in executive functioning performance in temporal lobe epilepsy. Epilepsy & Behavior : E&B. 121: 108088. PMID 34102472 DOI: 10.1016/j.yebeh.2021.108088  1
2021 Jaini R, Wolf MR, Yu Q, King AT, Frazier TW, Eng C. Maternal genetics influences fetal neurodevelopment and postnatal autism spectrum disorder-like phenotype by modulating in-utero immunosuppression. Translational Psychiatry. 11: 348. PMID 34091589 DOI: 10.1038/s41398-021-01472-x  1
2021 Sarn N, Thacker S, Lee H, Eng C. Germline nuclear-predominant Pten murine model exhibits impaired social and perseverative behavior, microglial activation, and increased oxytocinergic activity. Molecular Autism. 12: 41. PMID 34088332 DOI: 10.1186/s13229-021-00448-4  1
2021 Thacker S, Eng C. Transcriptome-(phospho)proteome characterization of brain of a germline model of cytoplasmic-predominant Pten expression with autism-like phenotypes. Npj Genomic Medicine. 6: 42. PMID 34078911 DOI: 10.1038/s41525-021-00201-z  1
2021 Hardan AY, Jo B, Frazier TW, Klaas P, Busch RM, Dies KA, Filip-Dhima R, Snow AV, Eng C, Hanna R, Zhang B, Sahin M. A randomized double-blind controlled trial of everolimus in individuals with mutations: Study design and statistical considerations. Contemporary Clinical Trials Communications. 21: 100733. PMID 33644493 DOI: 10.1016/j.conctc.2021.100733  1
2021 Cheng F, Zhao J, Wang Y, Lu W, Liu Z, Zhou Y, Martin WR, Wang R, Huang J, Hao T, Yue H, Ma J, Hou Y, Castrillon JA, Fang J, ... Eng C, et al. Comprehensive characterization of protein-protein interactions perturbed by disease mutations. Nature Genetics. PMID 33558758 DOI: 10.1038/s41588-020-00774-y  1
2021 Frazier TW, Jaini R, Busch RM, Wolf M, Sadler T, Klaas P, Hardan AY, Martinez-Agosto JA, Sahin M, Eng C. Cross-level analysis of molecular and neurobehavioral function in a prospective series of patients with germline heterozygous PTEN mutations with and without autism. Molecular Autism. 12: 5. PMID 33509259 DOI: 10.1186/s13229-020-00406-6  1
2020 Akhavanfard S, Yehia L, Padmanabhan R, Reynolds JP, Ni Y, Eng C. Germline EGFR variants are over-represented in adolescents and young adults (AYA) with adrenocortical carcinoma. Human Molecular Genetics. PMID 33326033 DOI: 10.1093/hmg/ddaa268  1
2020 Heald B, Keel E, Marquard J, Burke CA, Kalady MF, Church JM, Liska D, Mankaney G, Hurley K, Eng C. Using chatbots to screen for heritable cancer syndromes in patients undergoing routine colonoscopy. Journal of Medical Genetics. PMID 33168571 DOI: 10.1136/jmedgenet-2020-107294  1
2020 Thacker S, Sefyi M, Eng C. Alternative splicing landscape of the neural transcriptome in a cytoplasmic-predominant Pten expression murine model of autism-like Behavior. Translational Psychiatry. 10: 380. PMID 33159038 DOI: 10.1038/s41398-020-01068-x  1
2020 Kotsopoulos J, Gronwald J, McCuaig JM, Karlan BY, Eisen A, Tung N, Bordeleau L, Senter L, Eng C, Couch F, Fruscio R, Weitzel JN, Olopade O, Singer CF, Pal T, et al. Breastfeeding and the risk of epithelial ovarian cancer among women with a BRCA1 or BRCA2 mutation. Gynecologic Oncology. PMID 33010967 DOI: 10.1016/j.ygyno.2020.09.037  1
2020 Busch RM, Yehia L, Bazeley P, Seyfi M, Blümcke I, Hermann BP, Najm IM, Eng C. Verbal memory dysfunction is associated with alterations in brain transcriptome in dominant temporal lobe epilepsy. Epilepsia. PMID 32945555 DOI: 10.1111/Epi.16673  1
2020 Jaini R, Loya MG, King AT, Thacker S, Sarn NB, Yu Q, Stark GR, Eng C. Germline PTEN mutations are associated with a skewed peripheral immune repertoire in humans and mice. Human Molecular Genetics. PMID 32588888 DOI: 10.1093/Hmg/Ddaa118  1
2020 Kang SC, Jaini R, Hitomi M, Lee H, Sarn N, Thacker S, Eng C. Decreased nuclear Pten in neural stem cells contributes to deficits in neuronal maturation. Molecular Autism. 11: 43. PMID 32487265 DOI: 10.1186/S13229-020-00337-2  1
2020 Lee YR, Yehia L, Kishikawa T, Ni Y, Leach B, Zhang J, Panch N, Liu J, Wei W, Eng C, Pandolfi PP. WWP1 Gain-of-Function Inactivation of PTEN in Cancer Predisposition. The New England Journal of Medicine. 382: 2103-2116. PMID 32459922 DOI: 10.1056/Nejmoa1914919  1
2020 Mighell TL, Thacker S, Fombonne E, Eng C, O'Roak BJ. An Integrated Deep-Mutational-Scanning Approach Provides Clinical Insights on PTEN Genotype-Phenotype Relationships. American Journal of Human Genetics. PMID 32442409 DOI: 10.1016/J.Ajhg.2020.04.014  1
2020 Larsen LV, Mirebeau-Prunier D, Imai T, Alvarez-Escola C, Hasse-Lazar K, Censi S, Castroneves LA, Sakurai A, Kihara M, Horiuchi K, Barbu VD, Borson-Chazot F, Gimenez-Roqueplo AP, Pigny P, Pinson S, ... Eng C, et al. Primary hyperparathyroidism as first manifestation in MEN 2A: an international multicenter study. Endocrine Connections. PMID 32375120 DOI: 10.1530/Ec-20-0163  1
2020 Ngeow J, Eng C. Oh GxE! The Complexity of Body Mass Index and Colon Cancer Risk. Journal of the National Cancer Institute. PMID 32324885 DOI: 10.1093/Jnci/Djaa059  1
2020 Sheehan M, Heald B, Yanda C, Kelly ED, Grobmyer S, Eng C, Kalady M, Pederson H. Investigating the Link between Lynch Syndrome and Breast Cancer. European Journal of Breast Health. 16: 106-109. PMID 32285031 DOI: 10.5152/Ejbh.2020.5198  1
2020 Liu C, Zhao J, Lu W, Dai Y, Hockings J, Zhou Y, Nussinov R, Eng C, Cheng F. Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes. Plos Computational Biology. 16: e1007701. PMID 32101536 DOI: 10.1371/Journal.Pcbi.1007701  1
2020 Sarn N, Jaini R, Thacker S, Lee H, Dutta R, Eng C. Cytoplasmic-predominant Pten increases microglial activation and synaptic pruning in a murine model with autism-like phenotype. Molecular Psychiatry. PMID 32055008 DOI: 10.1038/S41380-020-0681-0  1
2020 Yehia L, Seyfi M, Niestroj LM, Padmanabhan R, Ni Y, Frazier TW, Lal D, Eng C. Copy Number Variation and Clinical Outcomes in Patients With Germline PTEN Mutations. Jama Network Open. 3: e1920415. PMID 32003824 DOI: 10.1001/jamanetworkopen.2019.20415  1
2020 Khare A, Burke CA, Heald B, O'Malley M, LaGuardia LA, Cruise MW, Liska D, Kalady M, Church JM, Eng C, Mankaney GN. Tu1217 THE EFFICACY OF LOWER ENDOSCOPIC SURVEILLANCE IN COWDEN'S SYNDROME Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)33228-5  1
2020 Akhavanfard S, Yehia L, Padmanabhan R, Romigh T, Ni Y, Eng C. 1. Germline EGFR variants over-represented in adolescent and young adult (AYA) females with adrenocortical carcinoma Cancer Genetics and Cytogenetics. 244: 1. DOI: 10.1016/J.Cancergen.2020.04.005  1
2019 Kotsopoulos J, Gronwald J, Lubinski J, McCuaig J, Lynch HT, Neuhausen SL, Foulkes WD, Weitzel JN, Senter L, Tung N, Eng C, Karlan B, Sun P, Narod SA. Does preventive oophorectomy increase the risk of depression in BRCA mutation carriers? Menopause (New York, N.Y.). PMID 31644510 DOI: 10.1097/Gme.0000000000001437  1
2019 Busch RM, Srivastava S, Hogue O, Frazier TW, Klaas P, Hardan A, Martinez-Agosto JA, Sahin M, Eng C. Neurobehavioral phenotype of autism spectrum disorder associated with germline heterozygous mutations in PTEN. Translational Psychiatry. 9: 253. PMID 31594918 DOI: 10.1038/S41398-019-0588-1  1
2019 Ngeow J, Eng C. PTEN in Hereditary and Sporadic Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 31570378 DOI: 10.1101/Cshperspect.A036087  1
2019 Yehia L, Ni Y, Feng F, Seyfi M, Sadler T, Frazier TW, Eng C. Distinct Alterations in Tricarboxylic Acid Cycle Metabolites Associate with Cancer and Autism Phenotypes in Cowden Syndrome and Bannayan-Riley-Ruvalcaba Syndrome. American Journal of Human Genetics. PMID 31564436 DOI: 10.1016/J.Ajhg.2019.09.004  1
2019 Abbas A, Romigh T, Eng C. PTEN interacts with RNA polymerase II to dephosphorylate polymerase II C-terminal domain. Oncotarget. 10: 4951-4959. PMID 31452836 DOI: 10.18632/Oncotarget.27128  1
2019 Neumann HPH, Tsoy U, Bancos I, Amodru V, Walz MK, Tirosh A, Kaur RJ, McKenzie T, Qi X, Bandgar T, Petrov R, Yukina MY, Roslyakova A, van der Horst-Schrivers ANA, Berends AMA, ... Eng C, et al. Comparison of Pheochromocytoma-Specific Morbidity and Mortality Among Adults With Bilateral Pheochromocytomas Undergoing Total Adrenalectomy vs Cortical-Sparing Adrenalectomy. Jama Network Open. 2: e198898. PMID 31397861 DOI: 10.1001/jamanetworkopen.2019.8898  1
2019 Cheng F, Lu W, Liu C, Fang J, Hou Y, Handy DE, Wang R, Zhao Y, Yang Y, Huang J, Hill DE, Vidal M, Eng C, Loscalzo J. A genome-wide positioning systems network algorithm for in silico drug repurposing. Nature Communications. 10: 3476. PMID 31375661 DOI: 10.1038/S41467-019-10744-6  1
2019 Chong ST, Tan KM, Kok CYL, Guan SP, Lai SH, Lim C, Hu J, Sturgis C, Eng C, Lam PYP, Ngeow J. IL13RA2 is differentially regulated in Papillary Thyroid Carcinoma versus Follicular Thyroid Carcinoma. The Journal of Clinical Endocrinology and Metabolism. PMID 31290966 DOI: 10.1210/Jc.2019-00040  1
2019 Abbas A, Padmanabhan R, Romigh T, Eng C. PTEN modulates gene transcription by redistributing genome-wide RNA polymerase II occupancy. Human Molecular Genetics. PMID 31127935 DOI: 10.1093/Hmg/Ddz112  1
2019 Smith IN, Thacker S, Seyfi M, Cheng F, Eng C. Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer. American Journal of Human Genetics. PMID 31006514 DOI: 10.1016/J.Ajhg.2019.03.009  1
2019 Getz TM, Hoffman GS, Padmanabhan R, Villa-Forte A, Roselli EE, Blackstone E, Johnston D, Pettersson G, Soltesz E, Svensson LG, Calabrese LH, Clifford AH, Eng C. Microbiomes of Inflammatory Thoracic Aortic Aneurysms Due to Giant Cell Arteritis and Clinically Isolated Aortitis Differ From Those of Non-Inflammatory Aneurysms. Pathogens & Immunity. 4: 105-123. PMID 30993253 DOI: 10.20411/pai.v4i1.269  1
2019 Metcalfe K, Eisen A, Senter L, Armel S, Bordeleau L, Meschino WS, Pal T, Lynch HT, Tung NM, Kwong A, Ainsworth P, Karlan B, Moller P, Eng C, Weitzel JN, et al. International trends in the uptake of cancer risk reduction strategies in women with a BRCA1 or BRCA2 mutation. British Journal of Cancer. PMID 30971774 DOI: 10.1038/S41416-019-0446-1  1
2019 Doherty C, Hogue O, Floden DP, Altemus JB, Najm IM, Eng C, Busch RM. BDNF and COMT, but not APOE, alleles are associated with psychiatric symptoms in refractory epilepsy. Epilepsy & Behavior : E&B. 94: 131-136. PMID 30909076 DOI: 10.1016/J.Yebeh.2019.02.032  1
2019 Lee H, Thacker S, Sarn N, Dutta R, Eng C. Constitutional mislocalization of Pten drives precocious maturation in oligodendrocytes and aberrant myelination in model of autism spectrum disorder. Translational Psychiatry. 9: 13. PMID 30664625 DOI: 10.1038/S41398-018-0364-7  1
2019 Castinetti F, Waguespack SG, Machens A, Uchino S, Lazaar K, Sanso G, Else T, Dvorakova S, Qi XP, Elisei R, Maia AL, Glod J, Lourenço DM, Valdes N, Mathiesen J, ... Eng C, et al. Natural history, treatment, and long-term follow up of patients with multiple endocrine neoplasia type 2B: an international, multicentre, retrospective study. The Lancet. Diabetes & Endocrinology. PMID 30660595 DOI: 10.1016/S2213-8587(18)30336-X  1
2019 Yehia L, Ngeow J, Eng C. PTEN-opathies: from biological insights to evidence-based precision medicine. The Journal of Clinical Investigation. PMID 30614812 DOI: 10.1172/Jci121277  1
2019 Akhavanfard S, Yehia L, Padmanabhan R, Romigh T, Ni Y, Eng C. Germline EGFR mutation and cancer predisposition in adolescent and young adult (AYA) females with adrenocortical carcinoma. Journal of Clinical Oncology. 37. DOI: 10.1200/Jco.2019.37.15_Suppl.E13014  1
2019 Pederson H, Heald B, Budd G, Bernhisel R, Cummings S, Saam J, Lancaster J, Grobmyer S, Eng C. Abstract P1-10-01: Defining the spectrum of germline variants among African American patients with triple negative breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P1-10-01  1
2019 Chong ST, Kok CY, Tan KM, Guan SP, Lai SH, Lim C, Hu J, Sturgis C, Eng C, Lam PY, Ngeow J. Abstract 2780: IL13RA2 is differentially regulated in papillary thyroid carcinoma versus follicular thyroid carcinoma Cancer Research. 79: 2780-2780. DOI: 10.1158/1538-7445.Am2019-2780  1
2019 Getz TM, Hoffman GS, Padmanabhan R, Villa-Forte A, Roselli EE, Blackstone E, Johnston D, Pettersson G, Soltesz E, Svensson LG, Calabrese LH, Clifford AH, Eng C. 183. Microbiome In Aortitis Rheumatology. 58. DOI: 10.1093/Rheumatology/Kez060.010  1
2018 Frazier TW, Klingemier EW, Parikh S, Speer L, Strauss MS, Eng C, Hardan AY, Youngstrom EA. Development and Validation of Objective and Quantitative Eye Tracking-Based Measures of Autism Risk and Symptom Levels. Journal of the American Academy of Child and Adolescent Psychiatry. 57: 858-866. PMID 30392627 DOI: 10.1016/J.Jaac.2018.06.023  1
2018 Rivera-Muñoz EA, Milko LV, Harrison SM, Azzariti DR, Kurtz CL, Lee K, Mester JL, Weaver MA, Currey E, Craigen W, Eng C, Funke B, Hegde M, Hershberger RE, Mao R, et al. ClinGen Variant Curation Expert Panel experiences and standardized processes for disease and gene-level specification of the ACMG/AMP guidelines for sequence variant interpretation. Human Mutation. 39: 1614-1622. PMID 30311389 DOI: 10.1002/Humu.23645  1
2018 Mester JL, Ghosh R, Pesaran T, Huether R, Karam R, Hruska KS, Costa HA, Lachlan K, Ngeow J, Barnholtz-Sloan J, Sesock K, Hernandez F, Zhang L, Milko L, Plon SE, ... Eng C, et al. Gene-specific criteria for PTEN variant curation: Recommendations from the ClinGen PTEN Expert Panel. Human Mutation. 39: 1581-1592. PMID 30311380 DOI: 10.1002/Humu.23636  1
2018 Feng F, Yehia L, Ni Y, Chang YS, Jhiang SM, Eng C. A non-pump function of sodium iodide symporter in thyroid cancer via crosstalk with PTEN signaling. Cancer Research. PMID 30217930 DOI: 10.1158/0008-5472.Can-18-1954  1
2018 Jehi L, Yehia L, Peterson C, Niazi F, Busch R, Prayson R, Ying Z, Bingaman W, Najm I, Eng C. Preliminary report: Late seizure recurrence years after epilepsy surgery may be associated with alterations in brain tissue transcriptome. Epilepsia Open. 3: 299-304. PMID 29881812 DOI: 10.1002/epi4.12119  1
2018 Neumann HPH, Young W, Krauss T, Bayley JP, Schiavi F, Opocher G, Boedeker C, Tirosh A, Castinetti F, Ruf J, Beltsevich D, Walz MK, Groeben H, Von Dobschuetz E, Gimm O, ... Eng C, et al. Genetics Informs Precision Practice in the Diagnosis and Management of Pheochromocytoma. Endocrine-Related Cancer. PMID 29794110 DOI: 10.1530/Erc-18-0085  1
2018 Kotsopoulos J, Gronwald J, Lynch HT, Eisen A, Neuhausen SL, Tung N, Ainsworth P, Weitzel JN, Pal T, Foulkes WD, Eng C, Singer CF, Senter L, Sun P, Lubinski J, et al. Age at first full-term birth and breast cancer risk in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment. PMID 29774471 DOI: 10.1007/S10549-018-4822-Y  1
2018 Krauss T, Ferrara AM, Links TP, Wellner U, Bancos I, Kvachenyuk A, Villar Gómez de Las Heras K, Yukina M, Petrov R, Bullivant G, von Duecker L, Jadhav SS, Ploeckinger U, Welin S, Schalin-Jantti C, ... Eng C, et al. Preventive medicine for von Hippel-Lindau disease-associated pancreatic neuroendocrine tumors. Endocrine-Related Cancer. PMID 29748190 DOI: 10.1530/Erc-18-0100  1
2018 Yehia L, Ni Y, Sesock K, Niazi F, Fletcher B, Chen HJ, LaFramboise T, Eng C. Unexpected cancer-predisposition gene variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome patients without underlying germline PTEN mutations. Plos Genetics. 14: e1007352. PMID 29684080 DOI: 10.1371/Journal.Pgen.1007352  1
2018 Smith IN, Thacker S, Jaini R, Eng C. Dynamics and Structural Stability Effects of Germline PTEN Mutations Associated with Cancer versus Autism Phenotypes. Journal of Biomolecular Structure & Dynamics. 1-44. PMID 29663862 DOI: 10.1080/07391102.2018.1465854  1
2018 Kim SJ, Huzarski T, Gronwald J, Singer CF, Møller P, Lynch HT, Armel S, Karlan BY, Foulkes WD, Neuhausen SL, Senter L, Eisen A, Eng C, Panchal S, Pal T, et al. Prospective evaluation of body size and breast cancer risk among BRCA1 and BRCA2 mutation carriers. International Journal of Epidemiology. PMID 29547931 DOI: 10.1093/Ije/Dyy039  1
2018 Lammert J, Lubinski J, Gronwald J, Huzarski T, Armel S, Eisen A, Meschino WS, Lynch HT, Snyder C, Eng C, Olopade OI, Ginsburg O, Foulkes WD, Elser C, Cohen SA, et al. Physical activity during adolescence and young adulthood and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment. PMID 29404807 DOI: 10.1007/S10549-018-4694-1  1
2018 Smith IN, Thacker S, Eng C. Abstract 4283: A structure network approach to predict the dynamics and structural stability effects of germline PTEN mutations associated with cancer versus autism phenotypes Cancer Research. 78: 4283-4283. DOI: 10.1158/1538-7445.Am2018-4283  1
2017 Bausch B, Tischler AS, Schmid KW, Leijon H, Eng C, Neumann HPH. Max Schottelius: Pioneer in Pheochromocytoma. Journal of the Endocrine Society. 1: 957-964. PMID 29264546 DOI: 10.1210/Js.2017-00208  1
2017 Yehia L, Ni Y, Eng C. Germline TTN variants are enriched in PTEN-wildtype Bannayan-Riley-Ruvalcaba syndrome. Npj Genomic Medicine. 2: 37. PMID 29263846 DOI: 10.1038/S41525-017-0039-Y  1
2017 Mukherjee PK, Wang H, Retuerto M, Zhang H, Burkey B, Ghannoum MA, Eng C. Bacteriome and mycobiome associations in oral tongue cancer. Oncotarget. 8: 97273-97289. PMID 29228609 DOI: 10.18632/Oncotarget.21921  1
2017 Wang H, Altemus J, Niazi F, Green H, Calhoun BC, Sturgis C, Grobmyer SR, Eng C. Breast tissue, oral and urinary microbiomes in breast cancer. Oncotarget. 8: 88122-88138. PMID 29152146 DOI: 10.18632/Oncotarget.21490  1
2017 Chen HJ, Romigh T, Sesock K, Eng C. Characterization of cryptic splicing in germline PTEN intronic variants in Cowden syndrome. Human Mutation. PMID 28677221 DOI: 10.1002/Humu.23288  1
2017 Castinetti F, Maia AL, Peczkowska M, Barontini M, Hasse-Lazar K, Links TP, Toledo RA, Dvorakova S, Mian C, Bugalho MJ, Zovato S, Alevizaki M, Kvachenyuk A, Bausch B, Loli P, ... Eng C, et al. THE PENETRANCE OF MEN2 PHEOCHROMOCYTOMA IS NOT ONLY DETERMINED BY RET MUTATIONS. Endocrine-Related Cancer. PMID 28649091 DOI: 10.1530/Erc-17-0189  1
2017 Frazier TW, Strauss M, Klingemier EW, Zetzer EE, Hardan AY, Eng C, Youngstrom EA. A Meta-Analysis of Gaze Differences to Social and Nonsocial Information Between Individuals With and Without Autism. Journal of the American Academy of Child and Adolescent Psychiatry. 56: 546-555. PMID 28647006 DOI: 10.1016/J.Jaac.2017.05.005  1
2017 Ngeow J, Sesock K, Eng C. Clinical Implications for Germline PTEN Spectrum Disorders. Endocrinology and Metabolism Clinics of North America. 46: 503-517. PMID 28476234 DOI: 10.1016/J.Ecl.2017.01.013  1
2017 Bausch B, Schiavi F, Ni Y, Welander J, Patocs A, Ngeow J, Wellner U, Malinoc A, Taschin E, Barbon G, Lanza V, Söderkvist P, Stenman A, Larsson C, Svahn F, ... Eng C, et al. Clinical Characterization of the Pheochromocytoma and Paraganglioma Susceptibility Genes SDHA, TMEM127, MAX, and SDHAF2 for Gene-Informed Prevention. Jama Oncology. PMID 28384794 DOI: 10.1001/Jamaoncol.2017.0223  1
2017 Yehia L, Ni Y, Eng C. Thyroglobulin in Metastatic Thyroid Cancer: Culprit or Red Herring? American Journal of Human Genetics. 100: 562-563. PMID 28257694 DOI: 10.1016/J.Ajhg.2017.01.023  1
2017 Arora HC, Eng C, Shoskes DA. Gut microbiome and chronic prostatitis/chronic pelvic pain syndrome. Annals of Translational Medicine. 5: 30. PMID 28217695 DOI: 10.21037/Atm.2016.12.32  1
2017 Wang H, Funchain P, Bebek G, Altemus J, Zhang H, Niazi F, Peterson C, Lee WT, Burkey BB, Eng C. Microbiomic differences in tumor and paired-normal tissue in head and neck squamous cell carcinomas. Genome Medicine. 9: 14. PMID 28173873 DOI: 10.1186/S13073-017-0405-5  1
2017 Yu W, Ni Y, Saji M, Ringel MD, Jaini R, Eng C. Cowden syndrome-associated germline succinate dehydrogenase complex subunit D (SDHD) variants cause PTEN-mediated down-regulation of autophagy in thyroid cancer cells. Human Molecular Genetics. PMID 28164237 DOI: 10.1093/Hmg/Ddx037  1
2017 Ngeow J, Eng C. Reply to G. Le Flahec et al. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 35: 377. PMID 28095271 DOI: 10.1200/Jco.2016.69.9405  1
2017 Kotsopoulos J, Huzarski T, Gronwald J, Singer CF, Moller P, Lynch HT, Armel S, Karlan B, Foulkes WD, Neuhausen SL, Senter L, Tung N, Weitzel JN, Eisen A, Metcalfe K, Eng C, et al. Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers. Journal of the National Cancer Institute. 109. PMID 27601060 DOI: 10.1093/Jnci/Djw177  1
2016 Heald B, Rybicki L, Clements D, Marquard J, Mester J, Noss R, Nardini M, Polk J, Psensky B, Rigelsky C, Schreiber A, Shealy A, Smith M, Eng C. Assessment of clinical workload for general and specialty genetic counsellors at an academic medical center: a tool for evaluating genetic counselling practices. Npj Genomic Medicine. 1: 16010. PMID 29263811 DOI: 10.1038/Npjgenmed.2016.10  1
2016 Ngeow J, Eng C. Precision medicine in heritable cancer: when somatic tumour testing and germline mutations meet. Npj Genomic Medicine. 1: 15006. PMID 29263804 DOI: 10.1038/Npjgenmed.2015.6  1
2016 Ni Y, Seballos S, Fletcher B, Romigh T, Yehia L, Mester J, Senter L, Niazi F, Saji M, Ringel MD, LaFramboise T, Eng C. Germline Compound Heterozygous Poly-glutamine Deletion in USF3 May Be Involved in Predisposition to Heritable and Sporadic Epithelial Thyroid Carcinoma. Human Molecular Genetics. PMID 28011713 DOI: 10.1093/Hmg/Ddw382  1
2016 Colby S, Yehia L, Niazi F, Chen J, Ni Y, Mester JL, Eng C. Exome sequencing reveals germline gain-of-function EGFR mutation in an adult with Lhermitte-Duclos disease. Cold Spring Harbor Molecular Case Studies. 2: a001230. PMID 27900366 DOI: 10.1101/mcs.a001230  1
2016 Chen HH, Händel N, Ngeow J, Muller J, Hühn M, Yang HT, Heindl M, Berbers RM, Hegazy AN, Kionke J, Yehia L, Sack U, Bläser F, Rensing-Ehl A, Reifenberger J, ... Eng C, et al. Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells. The Journal of Allergy and Clinical Immunology. PMID 27477328 DOI: 10.1016/J.Jaci.2016.03.059  1
2016 Svensson L, Arafat A, Roselli EE, Idrees JJ, Clifford A, Tan C, Hoffman G, Eng C, Langford CA, Rodriguez ER, Gornik HL, Blackstone EH, Sabik JF, Lytle BW. Erratum: Inflammatory disease of the aorta: Patterns and classification of giant cell aortitis, Takayasu arteritis, and nonsyndromic aortitis (Journal of Thoracic and Cardiovascular Surgery (2015) 149 (S170-S175)) The Journal of Thoracic and Cardiovascular Surgery. 152. PMID 27343932 DOI: 10.1016/J.Jtcvs.2016.04.009  1
2016 Fishbein AB, Lee TA, Cai M, Oh SS, Eng C, Hu D, Huntsman S, Farber HJ, Serebrisky D, Silverberg J, Williams LK, Seibold MA, Sen S, Borrell LN, Avila P, et al. Sensitization to mouse and cockroach allergens and asthma morbidity in urban minority youth: Genes-environments and Admixture in Latino American (GALA-II) and Study of African-Americans, Asthma, Genes, and Environments (SAGE-II). Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. PMID 27238578 DOI: 10.1016/J.Anai.2016.05.004  1
2016 Bi W, Glass IA, Muzny DM, Gibbs RA, Eng CM, Yang Y, Sun A. Whole exome sequencing identifies the first STRADA point mutation in a patient with polyhydramnios, megalencephaly, and symptomatic epilepsy syndrome (PMSE). American Journal of Medical Genetics. Part A. PMID 27170158 DOI: 10.1002/Ajmg.A.37727  1
2016 Ngeow J, Eng C. Mismatch Repair Deficiency in Colorectal Cancers: Is Somatic Genomic Testing the Grab-Bag for All Answers? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27161963 DOI: 10.1200/Jco.2016.66.7766  1
2016 Eng C, Karki S, Trivedi AN. Risk factors of stillbirths in Victoria (Australia): A case-control study. Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology. 1-4. PMID 27159049 DOI: 10.3109/01443615.2016.1157146  1
2016 White MJ, Risse-Adams O, Goddard P, Contreras MG, Adams J, Hu D, Eng C, Oh SS, Davis A, Meade K, Brigino-Buenaventura E, LeNoir MA, Bibbins-Domingo K, Pino-Yanes M, Burchard EG. Novel genetic risk factors for asthma in African American children: Precision Medicine and the SAGE II Study. Immunogenetics. PMID 27142222 DOI: 10.1007/S00251-016-0914-1  1
2016 Zhang J, Lachance V, Schaffner A, Li X, Fedick A, Kaye LE, Liao J, Rosenfeld J, Yachelevich N, Chu ML, Mitchell WG, Boles RG, Moran E, Tokita M, Gorman E, ... ... Eng C, et al. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. Plos Genetics. 12: e1005848. PMID 27120463 DOI: 10.1371/Journal.Pgen.1005848  1
2016 Nielsen SM, Rhodes L, Blanco I, Chung WK, Eng C, Maher ER, Richard S, Giles RH. Von Hippel-Lindau Disease: Genetics and Role of Genetic Counseling in a Multiple Neoplasia Syndrome. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27114602 DOI: 10.1200/Jco.2015.65.6140  1
2016 Nyfeler B, Eng CH. Revisiting autophagy addiction of tumor cells. Autophagy. 0. PMID 27097231 DOI: 10.1080/15548627.2016.1170265  1
2016 Bailey HH, Chuang LT, duPont NC, Eng C, Foxhall LE, Merrill JK, Wollins DS, Blanke CD. American Society of Clinical Oncology Statement: Human Papillomavirus Vaccination for Cancer Prevention. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 34: 1803-12. PMID 27069078 DOI: 10.1200/JCO.2016.67.2014  1
2016 McCormick Z, Cushman D, Marshall B, Caldwell M, Patel J, Ghannad L, Eng C, Makovitch S, Babu A, Chu SK, Marciniak C, Walega DR, Press J, Plastaras C, Kennedy DJ. Pain Reduction and Repeat Injections after Transforaminal Epidural Injection with Particulate versus Non-particulate Steroid for the Treatment of Chronic Painful Lumbosacral Radiculopathy. Pm & R : the Journal of Injury, Function, and Rehabilitation. PMID 27060648 DOI: 10.1016/j.pmrj.2016.03.011  1
2016 Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, Markunas CA, Richmond RC, Xu CJ, Küpers LK, Oh SS, Hoyo C, Gruzieva O, Söderhäll C, ... ... Eng C, et al. DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis. American Journal of Human Genetics. PMID 27040690 DOI: 10.1016/J.Ajhg.2016.02.019  1
2016 Chan PY, Carrera Silva EA, De Kouchkovsky D, Joannas LD, Hao L, Hu D, Huntsman S, Eng C, Licona-Limón P, Weinstein JS, Herbert DR, Craft JE, Flavell RA, Repetto S, Correale J, et al. The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity. Science (New York, N.Y.). 352: 99-103. PMID 27034374 DOI: 10.1126/Science.Aaf1358  1
2016 Ngeow J, Eng C. Germline PTEN Mutation Analysis for PTEN Hamartoma Tumor Syndrome. Methods in Molecular Biology (Clifton, N.J.). 1388: 63-73. PMID 27033071 DOI: 10.1007/978-1-4939-3299-3_6  1
2016 Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies. Nature Methods. PMID 27018579 DOI: 10.1038/Nmeth.3809  1
2016 Frazier TW, Klingemier EW, Beukemann M, Speer L, Markowitz L, Parikh S, Wexberg S, Giuliano K, Schulte E, Delahunty C, Ahuja V, Eng C, Manos MJ, Hardan AY, Youngstrom EA, et al. Development of an Objective Autism Risk Index Using Remote Eye Tracking. Journal of the American Academy of Child and Adolescent Psychiatry. 55: 301-9. PMID 27015721 DOI: 10.1016/J.Jaac.2016.01.011  1
2016 Eng CH, Yuzawa S, Wang G, Baidoo EE, Katz L, Keasling JD. Alteration of Polyketide Stereochemistry from anti to syn by a Ketoreductase Domain Exchange in a Type I Modular Polyketide Synthase Subunit. Biochemistry. PMID 26976746 DOI: 10.1021/Acs.Biochem.6B00129  1
2016 Shoskes DA, Altemus J, Polackwich AS, Tucky B, Wang H, Eng C. The Urinary Microbiome Differs Significantly between Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Controls as Well as between Patients with Different Clinical Phenotypes. Urology. PMID 26970449 DOI: 10.1016/J.Urology.2016.02.043  1
2016 You YN, Skibber JM, Hu CY, Crane CH, Das P, Kopetz ES, Eng C, Feig BW, Rodriguez-Bigas MA, Chang GJ. Impact of multimodal therapy in locally recurrent rectal cancer. The British Journal of Surgery. PMID 26933792 DOI: 10.1002/bjs.10079  1
2016 Shoskes DA, Wang H, Polackwich AS, Tucky B, Altemus J, Eng C. Analysis of Gut Microbiome Reveals Significant Differences Between Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Controls. The Journal of Urology. PMID 26930255 DOI: 10.1016/J.Juro.2016.02.2959  1
2016 Eng CL, Tong JC, Tan TW. Distinct Host Tropism Protein Signatures to Identify Possible Zoonotic Influenza A Viruses. Plos One. 11: e0150173. PMID 26915079 DOI: 10.1371/journal.pone.0150173  1
2016 Schwarz L, Aloia TA, Eng C, Chang GJ, Vauthey JN, Conrad C. Transthoracic Port Placement Increases Safety of Total Laparoscopic Posterior Sectionectomy. Annals of Surgical Oncology. PMID 26903047 DOI: 10.1245/s10434-016-5126-2  1
2016 Eng C, Bessudo A, Hart LL, Severtsev A, Gladkov O, Müller L, Kopp MV, Vladimirov V, Langdon R, Kotiv B, Barni S, Hsu C, Bolotin E, von Roemeling R, Schwartz B, et al. A randomized, placebo-controlled, phase 1/2 study of tivantinib (ARQ 197) in combination with irinotecan and cetuximab in patients with metastatic colorectal cancer with wild-type KRAS who have received first-line systemic therapy. International Journal of Cancer. Journal International Du Cancer. PMID 26891420 DOI: 10.1002/ijc.30049  1
2016 Gomez-Ospina N, Potter CJ, Xiao R, Manickam K, Kim MS, Kim KH, Shneider BL, Picarsic JL, Jacobson TA, Zhang J, He W, Liu P, Knisely AS, Finegold MJ, Muzny DM, ... ... Eng CM, et al. Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis. Nature Communications. 7: 10713. PMID 26888176 DOI: 10.1038/Ncomms10713  1
2016 Wang XS, Shi Q, Dougherty PM, Eng C, Mendoza TR, Williams LA, Fogelman DR, Cleeland CS. Prechemotherapy Touch Sensation Deficits Predict Oxaliplatin-Induced Neuropathy in Patients with Colorectal Cancer. Oncology. PMID 26882477 DOI: 10.1159/000443377  1
2016 He X, Thacker S, Romigh T, Yu Q, Frazier TW, Eng C. Erratum to: Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits. Molecular Autism. 7: 14. PMID 26843920 DOI: 10.1186/S13229-016-0075-Y  1
2016 James RA, Campbell IM, Chen ES, Boone PM, Rao MA, Bainbridge MN, Lupski JR, Yang Y, Eng CM, Posey JE, Shaw CA. A visual and curatorial approach to clinical variant prioritization and disease gene discovery in genome-wide diagnostics. Genome Medicine. 8: 13. PMID 26838676 DOI: 10.1186/S13073-016-0261-8  1
2016 Ngeow J, Eng C. HABP2 in Familial Non-medullary Thyroid Cancer: Will the Real Mutation Please Stand Up? Journal of the National Cancer Institute. 108. PMID 26832774 DOI: 10.1093/Jnci/Djw013  1
2016 Lalani SR, Liu P, Rosenfeld JA, Watkin LB, Chiang T, Leduc MS, Zhu W, Ding Y, Pan S, Vetrini F, Miyake CY, Shinawi M, Gambin T, Eldomery MK, Akdemir ZH, ... ... Eng CM, et al. Recurrent Muscle Weakness with Rhabdomyolysis, Metabolic Crises, and Cardiac Arrhythmia due to Bi-allelic TANGO2 Mutations. American Journal of Human Genetics. PMID 26805781 DOI: 10.1016/J.Ajhg.2015.12.008  1
2016 Kotsopoulos J, Huzarski T, Gronwald J, Moller P, Lynch HT, Neuhausen SL, Senter L, Demsky R, Foulkes WD, Eng C, Karlan B, Tung N, Singer CF, Sun P, Lubinski J, et al. Hormone replacement therapy after menopause and risk of breast cancer in BRCA1 mutation carriers: a case-control study. Breast Cancer Research and Treatment. PMID 26780555 DOI: 10.1007/S10549-016-3685-3  1
2016 White J, Beck CR, Harel T, Posey JE, Jhangiani SN, Tang S, Farwell KD, Powis Z, Mendelsohn NJ, Baker JA, Pollack L, Mason KJ, Wierenga KJ, Arrington DK, Hall M, ... ... Eng C, et al. POGZ truncating alleles cause syndromic intellectual disability. Genome Medicine. 8: 3. PMID 26739615 DOI: 10.1186/S13073-015-0253-0  1
2016 Ngeow J, Eng C. Rectal Cancer: Age Matters in the Affairs of Stage. Journal of the National Cancer Institute. 108. PMID 26719885 DOI: 10.1093/Jnci/Djv325  1
2016 Then YY, Ibrahim NA, Zainuddin N, Chieng BW, Eng CC, Ariffin H, Wan Yunus WMZ. Enhancement of tensile properties of surface treated oil palm mesocarp fiber/poly(Butylene succinate) biocomposite by (3-aminopropyl)trimethoxysilane Materials Science Forum. 846: 665-672. DOI: 10.4028/www.scientific.net/MSF.846.665  1
2016 Rogers JE, Dasari A, Eng C. The treatment of colorectal cancer during pregnancy: Cytotoxic chemotherapy and targeted therapy challenges Oncologist. 21: 563-570. DOI: 10.1634/theoncologist.2015-0362  1
2016 Eng CC, Ibrahim NA, Zainuddin N, Ariffin H, Yunus WMZW. Chemical modification of oil palm mesocarp fiber by methacrylate silane: Effects on morphology, mechanical, and dynamic mechanical properties of biodegradable hybrid composites Bioresources. 11: 861-872. DOI: 10.15376/biores.11.1.861-872  1
2016 Sankunny M, Nizialek E, Niazi F, Eng C. Abstract 3596: KLLN protects genomic stability by maintaining H3K9 trimethylation (H3K9me3) at the pericentric heterochromatin Cancer Research. 76: 3596-3596. DOI: 10.1158/1538-7445.Am2016-3596  1
2016 Ikeda Y, Kiyotani K, Yew PY, Kato T, Tamura K, Yap KL, Mester JL, Nielsen SH, Raymon GH, Eng C, Nakamura Y. Abstract 3480: Germline PARP4 mutations in patients with primary thyroid and breast cancers Cancer Research. 76: 3480-3480. DOI: 10.1158/1538-7445.Am2016-3480  1
2016 Farmer WA, Cohen BI, Eng CD. On the Validity of Certain Approximations Used in the Modeling of Nuclear EMP Ieee Transactions On Nuclear Science. 63: 1259-1267. DOI: 10.1109/TNS.2016.2518181  1
2016 Karagkounis G, Heald B, Liska D, Plesec T, Eng C, Church JM, Kalady MF. Clinical Implications of Microsatellite Instability in Rectal Cancer Journal of the American College of Surgeons. 223. DOI: 10.1016/J.Jamcollsurg.2016.06.073  1
2016 Fong NL, Eng CK, Pang V. Making sense of infinity through perception, operation and reason Man in India. 96: 447-455.  1
2015 Cavusoglu E, Marmur JD, Kassotis JT, Yanamadala S, Chopra V, Eng C. Usefulness of Plasma Matrix Metalloproteinase-3 Levels to Predict Myocardial Infarction in Men With and Without Acute Coronary Syndrome. The American Journal of Cardiology. PMID 26805660 DOI: 10.1016/j.amjcard.2015.12.022  1
2015 Ngeow J, Sesock K, Eng C. Breast cancer risk and clinical implications for germline PTEN mutation carriers. Breast Cancer Research and Treatment. PMID 26700035 DOI: 10.1007/S10549-015-3665-Z  1
2015 Ikeda Y, Kiyotani K, Yew PY, Kato T, Tamura K, Yap KL, Nielsen S, Mester J, Eng C, Nakamura Y, Grogan RH. Germline PARP4 mutations in patients with primary thyroid and breast cancers. Endocrine-Related Cancer. PMID 26699384 DOI: 10.1530/Erc-15-0359  1
2015 Gronwald J, Glass K, Rosen B, Karlan B, Tung N, Neuhausen SL, Moller P, Ainsworth P, Sun P, Narod SA, Lubinski J, Kotsopoulos J. Treatment of infertility does not increase the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation. Fertility and Sterility. PMID 26698676 DOI: 10.1016/J.Fertnstert.2015.11.034  1
2015 Eng CH, Wang Z, Tkach D, Toral-Barza L, Ugwonali S, Liu S, Fitzgerald SL, George E, Frias E, Cochran N, De Jesus R, McAllister G, Hoffman GR, Bray K, Lemon L, et al. Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy. Proceedings of the National Academy of Sciences of the United States of America. PMID 26677873 DOI: 10.1073/Pnas.1515617113  1
2015 Burrage LC, Charng WL, Eldomery MK, Willer JR, Davis EE, Lugtenberg D, Zhu W, Leduc MS, Akdemir ZC, Azamian M, Zapata G, Hernandez PP, Schoots J, de Munnik SA, Roepman R, ... ... Eng CM, et al. De Novo GMNN Mutations Cause Autosomal-Dominant Primordial Dwarfism Associated with Meier-Gorlin Syndrome. American Journal of Human Genetics. 97: 904-13. PMID 26637980 DOI: 10.1016/J.Ajhg.2015.11.006  1
2015 Straub MH, Kelly TR, Rideout BA, Eng C, Wynne J, Braun J, Johnson CK. Seroepidemiologic Survey of Potential Pathogens in Obligate and Facultative Scavenging Avian Species in California. Plos One. 10: e0143018. PMID 26606755 DOI: 10.1371/Journal.Pone.0143018  1
2015 Huang F, Chia YY, Eng CL, Lim YK, Yam KL, Tan SC, Hockenberry M. Evaluation of a Preoperative Clinic for Women With Gynecologic Cancer. Clinical Journal of Oncology Nursing. 19: 769-72. PMID 26583642 DOI: 10.1188/15.CJON.769-772  1
2015 He X, Thacker S, Romigh T, Yu Q, Frazier TW, Eng C. Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits. Molecular Autism. 6: 63. PMID 26579216 DOI: 10.1186/S13229-015-0056-6  1
2015 Winkler EA, Yue JK, McAllister TW, Temkin NR, Oh SS, Burchard EG, Hu D, Ferguson AR, Lingsma HF, Burke JF, Sorani MD, Rosand J, Yuh EL, Barber J, Tarapore PE, ... ... Eng C, et al. COMT Val (158) Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury. Neurogenetics. PMID 26576546 DOI: 10.1007/S10048-015-0467-8  1
2015 Yehia L, Niazi F, Ni Y, Ngeow J, Sankunny M, Liu Z, Wei W, Mester JL, Keri RA, Zhang B, Eng C. Germline Heterozygous Variants in SEC23B Are Associated with Cowden Syndrome and Enriched in Apparently Sporadic Thyroid Cancer. American Journal of Human Genetics. 97: 661-676. PMID 26522472 DOI: 10.1016/J.Ajhg.2015.10.001  1
2015 Frazier TW, Youngstrom EA, Hardan AY, Georgiades S, Constantino JN, Eng C. Quantitative autism symptom patterns recapitulate differential mechanisms of genetic transmission in single and multiple incidence families. Molecular Autism. 6: 58. PMID 26512313 DOI: 10.1186/S13229-015-0050-Z  1
2015 Liu X, George GC, Tsimberidou AM, Naing A, Wheler JJ, Kopetz S, Fu S, Piha-Paul SA, Eng C, Falchook GS, Janku F, Garrett C, Karp D, Kurzrock R, Zinner R, et al. Retreatment with anti-EGFR based therapies in metastatic colorectal cancer: impact of intervening time interval and prior anti-EGFR response. Bmc Cancer. 15: 713. PMID 26474549 DOI: 10.1186/S12885-015-1701-3  1
2015 Semple J, Metcalfe KA, Lubinski J, Huzarski T, Gronwald J, Armel S, Lynch HT, Karlan B, Foulkes W, Singer CF, Neuhausen SL, Eng C, Iqbal J, Narod SA. Does the age of breast cancer diagnosis in first-degree relatives impact on the risk of breast cancer in BRCA1 and BRCA2 mutation carriers? Breast Cancer Research and Treatment. 154: 163-9. PMID 26467043 DOI: 10.1007/S10549-015-3596-8  1
2015 Westerfield LE, Stover SR, Mathur VS, Nassef SA, Carter TG, Yang Y, Eng CM, Van den Veyver IB. Reproductive genetic counseling challenges associated with diagnostic exome sequencing in a large academic private reproductive genetic counseling practice. Prenatal Diagnosis. PMID 26275793 DOI: 10.1002/pd.4674  1
2015 Feng H, Zhang W, Liu W, Yu L, Qian Y, Wang J, Wang JJ, Eng C, Liu CJ, Jones KW, Tappero R. Synchrotron micro-scale study of trace metal transport and distribution in Spartina alterniflora root system in Yangtze River intertidal zone. Environmental Science and Pollution Research International. PMID 26208662 DOI: 10.1007/S11356-015-5068-4  1
2015 Eng C. Circulating DNA biomarkers: A primer for metastatic colorectal cancer? The Lancet Oncology. 16: 878-879. PMID 26184521 DOI: 10.1016/S1470-2045(15)00061-3  1
2015 Ngeow J, Liu C, Zhou K, Frick KD, Matchar DB, Eng C. Detecting Germline PTEN Mutations Among At-Risk Patients With Cancer: An Age- and Sex-Specific Cost-Effectiveness Analysis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 2537-44. PMID 26169622 DOI: 10.1200/Jco.2014.60.3456  1
2015 Ngeow J, Yu W, Yehia L, Niazi F, Chen J, Tang X, Heald B, Lei J, Romigh T, Tucker-Kellogg L, Lim KH, Song H, Eng C. Exome Sequencing Reveals Germline SMAD9 Mutation that Reduces PTEN Expression and is Associated with Hamartomatous Polyposis and Gastrointestinal Ganglioneuromas. Gastroenterology. PMID 26122142 DOI: 10.1053/J.Gastro.2015.06.027  1
2015 Wang J, Eng C, Chen-Wiegart YC, Wang J. Probing three-dimensional sodiation-desodiation equilibrium in sodium-ion batteries by in situ hard X-ray nanotomography. Nature Communications. 6: 7496. PMID 26112384 DOI: 10.1038/ncomms8496  1
2015 Ngeow J, Eng C. New Genetic and Genomic Approaches After the Genome-wide Association Study Era--Back to the Future. Gastroenterology. 149: 1138-41. PMID 26073374 DOI: 10.1053/J.Gastro.2015.05.060  1
2015 Park DS, Brown B, Eng C, Huntsman S, Hu D, Torgerson DG, Burchard EG, Zaitlen N. Adapt-Mix: learning local genetic correlation structure improves summary statistics-based analyses. Bioinformatics (Oxford, England). 31: i181-i189. PMID 26072481 DOI: 10.1093/Bioinformatics/Btv230  1
2015 Reddy SM, Kopetz S, Morris J, Parikh N, Qiao W, Overman MJ, Fogelman D, Shureiqi I, Jacobs C, Malik Z, Jimenez CA, Wolff RA, Abbruzzese JL, Gallick G, Eng C. Phase II study of saracatinib (AZD0530) in patients with previously treated metastatic colorectal cancer. Investigational New Drugs. 33: 977-84. PMID 26062928 DOI: 10.1007/S10637-015-0257-Z  1
2015 Sutton J, Orloff MS, Michener C, Chiesa-Vottero A, Prayson R, Nowacki AS, Eng C. Association of specific PTEN/10q haplotypes with endometrial cancer phenotypes in African-American and European American women. Gynecologic Oncology. PMID 26026735 DOI: 10.1016/J.Ygyno.2015.05.024  1
2015 Eng CM, Arnold AS, Biewener AA, Lieberman DE. The human iliotibial band is specialized for elastic energy storage compared with the chimp fascia lata. The Journal of Experimental Biology. PMID 26026035 DOI: 10.1242/Jeb.117952  1
2015 Acosta-Herrera M, Pino-Yanes M, Ma SF, Barreto-Luis A, Corrales A, Cumplido J, Pérez-Rodríguez E, Campo P, Eng C, García-Robaina JC, Quintela I, Villar J, Blanca M, Carracedo Á, Carrillo T, et al. Fine mapping of the myosin light chain kinase gene (MYLK) replicates the association with asthma in populations of Spanish descent. The Journal of Allergy and Clinical Immunology. PMID 26025125 DOI: 10.1016/J.Jaci.2015.04.025  1
2015 Baran Y, Subramaniam M, Biton A, Tukiainen T, Tsang EK, Rivas MA, Pirinen M, Gutierrez-Arcelus M, Smith KS, Kukurba KR, Zhang R, Eng C, Torgerson DG, Urbanek C, et al. The landscape of genomic imprinting across diverse adult human tissues. Genome Research. 25: 927-36. PMID 25953952 DOI: 10.1101/Gr.192278.115  1
2015 Toledo RA, Maciel RM, Erlic Z, Lourenço DM, Cerutti JM, Eng C, Neumann HP, Toledo SP. RET Y791F Variant Does Not Increase the Risk for Medullary Thyroid Carcinoma. Thyroid : Official Journal of the American Thyroid Association. 25: 973-4. PMID 25950813 DOI: 10.1089/Thy.2015.0168  1
2015 Brehm JM, Ramratnam SK, Tse SM, Croteau-Chonka DC, Pino-Yanes M, Rosas-Salazar C, Litonjua AA, Raby BA, Boutaoui N, Han YY, Chen W, Forno E, Marsland AL, Nugent NR, Eng C, et al. Stress and Bronchodilator Response in Children with Asthma. American Journal of Respiratory and Critical Care Medicine. 192: 47-56. PMID 25918834 DOI: 10.1164/Rccm.201501-0037Oc  1
2015 Tilot AK, Frazier TW, Eng C. Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 609-19. PMID 25916396 DOI: 10.1007/S13311-015-0356-8  1
2015 Bausch B, Wellner U, Peyre M, Boedeker CC, Hes FJ, Anglani M, de Campos JM, Kanno H, Maher ER, Krauss T, Sansó G, Barontini M, Letizia C, Hader C, Schiavi F, ... Eng C, et al. Characterization of endolymphatic sac tumors and von Hippel-Lindau disease in the International Endolymphatic Sac Tumor Registry. Head & Neck. PMID 25867206 DOI: 10.1002/Hed.24067  1
2015 Park DS, Baran Y, Hormozdiari F, Eng C, Torgerson DG, Burchard EG, Zaitlen N. PIGS: improved estimates of identity-by-descent probabilities by probabilistic IBD graph sampling. Bmc Bioinformatics. 16: S9. PMID 25860540 DOI: 10.1186/1471-2105-16-S5-S9  1
2015 Segev Y, Rosen B, Lubinski J, Gronwald J, Lynch HT, Moller P, Kim-Sing C, Ghadirian P, Karlan B, Eng C, Gilchrist D, Neuhausen SL, Eisen A, Friedman E, Euhus D, et al. Risk factors for endometrial cancer among women with a BRCA1 or BRCA2 mutation: a case control study. Familial Cancer. PMID 25838159 DOI: 10.1007/S10689-015-9798-8  1
2015 Tilot AK, Bebek G, Niazi F, Altemus JB, Romigh T, Frazier TW, Eng C. Neural transcriptome of constitutional Pten dysfunction in mice and its relevance to human idiopathic autism spectrum disorder. Molecular Psychiatry. PMID 25754085 DOI: 10.1038/Mp.2015.17  1
2015 Overman MJ, Eng C, Raghav K, Matamoros A, Taggart M, Foo WC, Fournier K. Challenges of efficacy assessments in pseudomyxoma peritonea Oncologist. 20: e3-e4. PMID 25745054 DOI: 10.1634/theoncologist.2014-0415  1
2015 McGarry ME, Castellanos E, Thakur N, Oh SS, Eng C, Davis A, Meade K, LeNoir MA, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, Bibbins-Domingo K, et al. Obesity and bronchodilator response in black and Hispanic children and adolescents with asthma. Chest. 147: 1591-8. PMID 25742612 DOI: 10.1378/Chest.14-2689  1
2015 Cavusoglu E, Marmur JD, Chhabra S, Hojjati MR, Yanamadala S, Chopra V, Eng C, Jiang XC. Elevated baseline plasma phospholipid protein (PLTP) levels are an independent predictor of long-term all-cause mortality in patients with diabetes mellitus and known or suspected coronary artery disease. Atherosclerosis. 239: 503-8. PMID 25710294 DOI: 10.1016/j.atherosclerosis.2015.02.017  1
2015 Ni Y, Seballos S, Ganapathi S, Gurin D, Fletcher B, Ngeow J, Nagy R, Kloos RT, Ringel MD, LaFramboise T, Eng C. Germline and somatic SDHx alterations in apparently sporadic differentiated thyroid cancer. Endocrine-Related Cancer. 22: 121-30. PMID 25694510 DOI: 10.1530/Erc-14-0537  1
2015 Chen ZY, Raghav K, Lieu CH, Jiang ZQ, Eng C, Vauthey JN, Chang GJ, Qiao W, Morris J, Hong D, Hoff P, Tran H, Menter DG, Heymach J, Overman M, et al. Cytokine profile and prognostic significance of high neutrophil-lymphocyte ratio in colorectal cancer. British Journal of Cancer. 112: 1088-97. PMID 25688736 DOI: 10.1038/Bjc.2015.61  1
2015 Nizialek EA, Mester JL, Dhiman VK, Smiraglia DJ, Eng C. KLLN epigenotype-phenotype associations in Cowden syndrome. European Journal of Human Genetics : Ejhg. 23: 1538-43. PMID 25669429 DOI: 10.1038/Ejhg.2015.8  1
2015 Kersey DC, Holland J, Eng C. Reproductive activity in the peninsular pronghorn determined from excreted gonadal steroid metabolites Zoo Biology. 34: 183-188. PMID 25652944 DOI: 10.1002/zoo.21199  1
2015 Onyango JO, Chung MS, Eng CH, Klees LM, Langenbacher R, Yao L, An M. Noncanonical amino acids to improve the pH response of pHLIP insertion at tumor acidity. Angewandte Chemie (International Ed. in English). 54: 3658-63. PMID 25650762 DOI: 10.1002/Anie.201409770  1
2015 Cavusoglu E, Marmur JD, Hegde S, Yanamadala S, Batuman OA, Chopra V, Ay G, Eng C. Relation of baseline plasma MMP-1 levels to long-term all-cause mortality in patients with known or suspected coronary artery disease referred for coronary angiography. Atherosclerosis. 239: 268-75. PMID 25635325 DOI: 10.1016/j.atherosclerosis.2015.01.003  1
2015 Morelli MP, Overman MJ, Dasari A, Kazmi SM, Mazard T, Vilar E, Morris VK, Lee MS, Herron D, Eng C, Morris J, Kee BK, Janku F, Deaton FL, Garrett C, et al. Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 26: 731-6. PMID 25628445 DOI: 10.1093/annonc/mdv005  1
2015 Vijverberg SJ, Koster ES, Tavendale R, Leusink M, Koenderman L, Raaijmakers JA, Postma DS, Koppelman GH, Turner SW, Mukhopadhyay S, Tse SM, Tantisira KG, Hawcutt DB, Francis B, Pirmohamed M, ... ... Eng C, et al. ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 45: 1051-9. PMID 25616159 DOI: 10.1111/Cea.12492  1
2015 Mester JL, Mercer M, Goldenberg A, Moore RA, Eng C, Sharp RR. Communicating with biobank participants: preferences for receiving and providing updates to researchers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 24: 708-12. PMID 25597748 DOI: 10.1158/1055-9965.Epi-13-1375  1
2015 von Dobschuetz E, Leijon H, Schalin-Jäntti C, Schiavi F, Brauckhoff M, Peczkowska M, Spiazzi G, Demattè S, Cecchini ME, Sartorato P, Krajewska J, Hasse-Lazar K, Roszkowska-Purska K, Taschin E, Malinoc A, ... ... Eng C, et al. A registry-based study of thyroid paraganglioma: histological and genetic characteristics. Endocrine-Related Cancer. 22: 191-204. PMID 25595276 DOI: 10.1530/Erc-14-0558  1
2015 Igartua C, Myers RA, Mathias RA, Pino-Yanes M, Eng C, Graves PE, Levin AM, Del-Rio-Navarro BE, Jackson DJ, Livne OE, Rafaels N, Edlund CK, Yang JJ, Huntsman S, Salam MT, et al. Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma. Nature Communications. 6: 5965. PMID 25591454 DOI: 10.1038/Ncomms6965  1
2015 Choe JH, Overman MJ, Fournier KF, Royal RE, Ohinata A, Rafeeq S, Beaty K, Phillips JK, Wolff RA, Mansfield PF, Eng C. Improved Survival with Anti-VEGF Therapy in the Treatment of Unresectable Appendiceal Epithelial Neoplasms. Annals of Surgical Oncology. PMID 25582740 DOI: 10.1245/s10434-014-4335-9  1
2015 Bogaerts J, Sydes MR, Keat N, McConnell A, Benson A, Ho A, Roth A, Fortpied C, Eng C, Peckitt C, Coens C, Pettaway C, Arnold D, Hall E, Marshall E, et al. Clinical trial designs for rare diseases: studies developed and discussed by the International Rare Cancers Initiative. European Journal of Cancer (Oxford, England : 1990). 51: 271-81. PMID 25542058 DOI: 10.1016/j.ejca.2014.10.027  1
2015 Pereira AA, Rego JF, Morris V, Overman MJ, Eng C, Garrett CR, Boutin AT, Ferrarotto R, Lee M, Jiang ZQ, Hoff PM, Vauthey JN, Vilar E, Maru D, Kopetz S. Association between KRAS mutation and lung metastasis in advanced colorectal cancer. British Journal of Cancer. 112: 424-8. PMID 25535726 DOI: 10.1038/bjc.2014.619  1
2015 Borad MJ, Reddy SG, Bahary N, Uronis HE, Sigal D, Cohn AL, Schelman WR, Stephenson J, Chiorean EG, Rosen PJ, Ulrich B, Dragovich T, Del Prete SA, Rarick M, Eng C, et al. Randomized Phase II Trial of Gemcitabine Plus TH-302 Versus Gemcitabine in Patients With Advanced Pancreatic Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 1475-81. PMID 25512461 DOI: 10.1200/JCO.2014.55.7504  1
2015 Pino-Yanes M, Gignoux CR, Galanter JM, Levin AM, Campbell CD, Eng C, Huntsman S, Nishimura KK, Gourraud PA, Mohajeri K, O'Roak BJ, Hu D, Mathias RA, Nguyen EA, Roth LA, et al. Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos. The Journal of Allergy and Clinical Immunology. 135: 1502-10. PMID 25488688 DOI: 10.1016/J.Jaci.2014.10.033  1
2015 Ngeow J, Eng C. PTEN hamartoma tumor syndrome: clinical risk assessment and management protocol. Methods (San Diego, Calif.). 77: 11-9. PMID 25461771 DOI: 10.1016/J.Ymeth.2014.10.011  1
2015 Mahdi H, Mester JL, Nizialek EA, Ngeow J, Michener C, Eng C. Germline PTEN, SDHB-D, and KLLN alterations in endometrial cancer patients with Cowden and Cowden-like syndromes: an international, multicenter, prospective study. Cancer. 121: 688-96. PMID 25376524 DOI: 10.1002/Cncr.29106  1
2015 Hsu HY, Yu HY, Lou JH, Eng CJ. Relationships among sexual self-concept and sexual risk cognition toward sexual self-efficacy in adolescents: cause-and-effect model testing. Japan Journal of Nursing Science : Jjns. 12: 124-34. PMID 25346398 DOI: 10.1111/jjns.12056  1
2015 Pino-Yanes M, Thakur N, Gignoux CR, Galanter JM, Roth LA, Eng C, Nishimura KK, Oh SS, Vora H, Huntsman S, Nguyen EA, Hu D, Drake KA, Conti DV, Moreno-Estrada A, et al. Genetic ancestry influences asthma susceptibility and lung function among Latinos. The Journal of Allergy and Clinical Immunology. 135: 228-35. PMID 25301036 DOI: 10.1016/J.Jaci.2014.07.053  1
2015 Svensson LG, Arafat A, Roselli EE, Idrees J, Clifford A, Tan C, Hoffman G, Eng C, Langford C, Rodriguez ER, Gornik HL, Blackstone E, Sabik JF, Lytle BW. Inflammatory disease of the aorta: patterns and classification of giant cell aortitis, Takayasu arteritis, and nonsyndromic aortitis. The Journal of Thoracic and Cardiovascular Surgery. 149: S170-5. PMID 25218529 DOI: 10.1016/J.Jtcvs.2014.08.003  1
2015 Yu W, He X, Ni Y, Ngeow J, Eng C. Cowden syndrome-associated germline SDHD variants alter PTEN nuclear translocation through SRC-induced PTEN oxidation. Human Molecular Genetics. 24: 142-53. PMID 25149476 DOI: 10.1093/Hmg/Ddu425  1
2015 Mester J, Eng C. Cowden syndrome: Recognizing and managing a not-so-rare hereditary cancer syndrome Journal of Surgical Oncology. 111: 125-130. PMID 25132236 DOI: 10.1002/Jso.23735  1
2015 Wu L, de Bruin A, Wang H, Simmons T, Cleghorn W, Goldenberg LE, Sites E, Sandy A, Trimboli A, Fernandez SA, Eng C, Shapiro C, Leone G. Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis Oncogene. 34: 119-128. PMID 24276244 DOI: 10.1038/Onc.2013.511  1
2015 Xekouki P, Szarek E, Bullova P, Giubellino A, Quezado M, Mastroyannis SA, Mastorakos P, Wassif CA, Raygada M, Rentia N, Dye L, Cougnoux A, Koziol D, De La Luz Sierra M, Lyssikatos C, ... ... Eng C, et al. Pituitary adenoma with paraganglioma/pheochromocytoma (3PAs) and succinate dehydrogenase defects in humans and mice Journal of Clinical Endocrinology and Metabolism. 100: E710-E719. DOI: 10.1210/jc.2014-4297  1
2015 Morenus LS, Eng CW, Takahatake N, Rambaldi DC. 16th-and 17th-century Italian chiaroscuro woodcuts: Instrumental analysis, degradation, and conservation Journal of the American Institute For Conservation. 54: 238-271. DOI: 10.1179/1945233015Y.0000000008  1
2015 Ngeow J, Liu C, Zhou K, Frick K, Matchar DB, Eng C. Abstract 3732: Detecting germline PTEN mutations among at-risk cancer patients: An age and gender-specific cost effectiveness analysis Cancer Research. 75: 3732-3732. DOI: 10.1158/1538-7445.Am2015-3732  1
2015 Knehr KW, Eng C, Chen-Wiegart YCK, Wang J, West AC. In Situ Transmission X-Ray Microscopy of the Lead Sulfate Film Formation on Lead in Sulfuric Acid Journal of the Electrochemical Society. 162: A255-A261. DOI: 10.1149/2.0141503Jes  1
2015 van den Veyver IB, Van den Veyver IB, Eng CM. Genome-wide sequencing for prenatal detection of fetal single-gene disorders Cold Spring Harbor Perspectives in Medicine. 5. DOI: 10.1101/cshperspect.a023077  1
2015 Yang Y, Muzny DM, Xia F, Niu Z, Person R, Ding Y, Ward P, Braxton A, Wang M, Buhay C, Veeraraghavan N, Hawes A, Chiang T, Leduc M, Beuten J, ... ... Eng CM, et al. Molecular findings among patients referred for clinical whole-exome sequencing: Editorial comment Obstetrical and Gynecological Survey. 70: 164-167. DOI: 10.1097/01.Ogx.0000462915.64193.1B  1
2015 Nizialek EA, Sankunny M, Niazi F, Eng C. Cancer-predisposition gene KLLN maintains pericentric H3K9 trimethylation protecting genomic stability Nucleic Acids Research. 44: 3586-3594. DOI: 10.1093/nar/gkv1481  1
2015 Ma W, Yarlagadda PKDV, Eng C. Pedestrian dynamics in real and simulated world Journal of Urban Planning and Development. 141. DOI: 10.1061/(ASCE)UP.1943-5444.0000232  1
2015 Heald B, Burke CA, Kalady M, Eng C. ACG guidelines on management of PTEN-hamartoma tumor syndrome: Does the evidence support so much so young? American Journal of Gastroenterology. 110: 1733-1734. DOI: 10.1038/ajg.2015.368  1
2015 Eng CJ, Pai HC. Determinants of nursing competence of nursing students in Taiwan: The role of self-reflection and insight Nurse Education Today. 35: 450-455. DOI: 10.1016/j.nedt.2014.11.021  1
2015 Pancheri FQ, Eng CM, Lieberman DE, Biewener AA, Dorfmann L. Corrigendum to: A constitutive description of the anisotropic response of the fascia lata Journal of the Mechanical Behavior of Biomedical Materials. DOI: 10.1016/J.Jmbbm.2015.05.022  1
2015 Eng CM, Arnold AS, Lieberman DE, Biewener AA. The capacity of the human iliotibial band to store elastic energy during running Journal of Biomechanics. DOI: 10.1016/j.jbiomech.2015.06.017  1
2015 Knehr KW, Eng C, Wang J, West AC. Transmission X-Ray Microscopy of the Galvanostatic Growth of Lead Sulfate on Lead: Impact of Lignosulfonate Electrochimica Acta. 168: 346-355. DOI: 10.1016/J.Electacta.2015.04.022  1
2015 Cavusoglu E, Marmur JD, Yanamadala S, Chopra V, Hegde S, Nazli A, Singh KP, Zhang M, Eng C. Elevated baseline plasma IL-8 levels are an independent predictor of long-term all-cause mortality in patients with acute coronary syndrome Atherosclerosis. 242: 589-594. DOI: 10.1016/j.atherosclerosis.2015.08.022  1
2015 Dawood S, Sirohi B, Shrikhande SV, Toh HC, Eng C. Potential Prognostic Impact of Baseline CEA Level and Surgery of Primary Tumor Among Patients with Synchronous Stage IV Colorectal Cancer: A Large Population Based Study Indian Journal of Surgical Oncology. 6: 198-206. DOI: 10.1007/s13193-015-0419-7  1
2015 Ahmed SU, Eng C. Colorectal cancer survivorship management Advances in Cancer Survivorship Management. 71-93. DOI: 10.1007/978-1-4939-0986-5_6  1
2015 Nakashima MO, Shetty S, Chicka M, Flagg A, Eng C, Cotta CV. Transient abnormal myelopoiesis of a newborn not associated with chromosome 21 abnormalities or GATA1 mutations Pediatric Blood and Cancer. 62: 353-355. DOI: 10.1002/pbc.25226  1
2015 Brownstein CA, Holm IA, Ramoni R, Goldstein DB, Bacino C, Lee B, Eng C, Veeraghavan N, Bernick D, Brownstein C, Holm I, Kohane I, McCray A, Splinter K, Shashi V, et al. Data Sharing in the Undiagnosed Diseases Network Human Mutation. 36: 985-988. DOI: 10.1002/humu.22840  1
2015 Eng CK, Asih HM. An integrated robust optimization model of capacity planning under demand uncertainty in electronic industry International Journal of Mechanical and Mechatronics Engineering. 15: 88-96.  1
2015 Eng CK, Ching HW, Siong BC. Paired-cell overlapping loops of cards with authorization simulation in job shop environment International Journal of Mechanical and Mechatronics Engineering. 15: 68-73.  1
2014 Ha D, Mester J, Eng C, Farha S. Pulmonary arterial hypertension in a patient with Cowden syndrome and the PTEN mutation. Pulmonary Circulation. 4: 728-31. PMID 25610608 DOI: 10.1086/678552  1
2014 Eng CL, Tong JC, Tan TW. Predicting host tropism of influenza A virus proteins using random forest. Bmc Medical Genomics. 7: S1. PMID 25521718 DOI: 10.1186/1755-8794-7-S3-S1  1
2014 Hsu A, Conell-Price J, Stijacic Cenzer I, Eng C, Huang AJ, Rice-Trumble K, Lee SJ. Predictors of urinary incontinence in community-dwelling frail older adults with diabetes mellitus in a cross-sectional study. Bmc Geriatrics. 14: 137. PMID 25514968 DOI: 10.1186/1471-2318-14-137  1
2014 Eng C, Chang GJ, You YN, Das P, Rodriguez-Bigas M, Xing Y, Vauthey JN, Rogers JE, Ohinata A, Pathak P, Sethi S, Phillips JK, Crane CH, Wolff RA. The role of systemic chemotherapy and multidisciplinary management in improving the overall survival of patients with metastatic squamous cell carcinoma of the anal canal. Oncotarget. 5: 11133-42. PMID 25373735 DOI: 10.18632/ONCOTARGET.2563  1
2014 Fejerman L, Ahmadiyeh N, Hu D, Huntsman S, Beckman KB, Caswell JL, Tsung K, John EM, Torres-Mejia G, Carvajal-Carmona L, Echeverry MM, Tuazon AM, Ramirez C, Gignoux CR, ... Eng C, et al. Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25. Nature Communications. 5: 5260. PMID 25327703 DOI: 10.1038/Ncomms6260  1
2014 Scollon S, Bergstrom K, Kerstein RA, Wang T, Hilsenbeck SG, Ramamurthy U, Gibbs RA, Eng CM, Chintagumpala MM, Berg SL, McCullough LB, McGuire AL, Plon SE, Parsons DW. Obtaining informed consent for clinical tumor and germline exome sequencing of newly diagnosed childhood cancer patients. Genome Medicine. 6: 69. PMID 25317207 DOI: 10.1186/S13073-014-0069-3  1
2014 Frazier TW, Embacher R, Tilot AK, Koenig K, Mester J, Eng C. Molecular and phenotypic abnormalities in individuals with germline heterozygous PTEN mutations and autism. Molecular Psychiatry. PMID 25288137 DOI: 10.1038/Mp.2014.125  1
2014 Shanware NP, Bray K, Eng CH, Wang F, Follettie M, Myers J, Fantin VR, Abraham RT. Glutamine deprivation stimulates mTOR-JNK-dependent chemokine secretion. Nature Communications. 5: 4900. PMID 25254627 DOI: 10.1038/Ncomms5900  1
2014 Sturgeon JD, Crane CH, Krishnan S, Minsky BD, Skibber JM, Rodriguez-Bigas MA, Chang GJ, You YN, Eng C, Das P. Definitive Chemoradiation for Squamous Cell Carcinoma of the Rectum. American Journal of Clinical Oncology. PMID 25222072 DOI: 10.1097/COC.0000000000000126  1
2014 Eng C, Kramer CK, Zinman B, Retnakaran R. Glucagon-like peptide-1 receptor agonist and basal insulin combination treatment for the management of type 2 diabetes: A systematic review and meta-analysis The Lancet. 384: 2228-2234. PMID 25220191 DOI: 10.1016/S0140-6736(14)61335-0  1
2014 de Carvalho Barbosa M, Kosturakis AK, Eng C, Wendelschafer-Crabb G, Kennedy WR, Simone DA, Wang XS, Cleeland CS, Dougherty PM. A quantitative sensory analysis of peripheral neuropathy in colorectal cancer and its exacerbation by oxaliplatin chemotherapy. Cancer Research. 74: 5955-62. PMID 25183707 DOI: 10.1158/0008-5472.Can-14-2060  1
2014 Finkelstein ME, Kuspa ZE, Welch A, Eng C, Clark M, Burnett J, Smith DR. Linking cases of illegal shootings of the endangered California condor using stable lead isotope analysis. Environmental Research. 134: 270-9. PMID 25173094 DOI: 10.1016/j.envres.2014.07.022  1
2014 Campbell CD, Mohajeri K, Malig M, Hormozdiari F, Nelson B, Du G, Patterson KM, Eng C, Torgerson DG, Hu D, Herman C, Chong JX, Ko A, O'Roak BJ, Krumm N, et al. Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma. Plos One. 9: e104396. PMID 25116239 DOI: 10.1371/Journal.Pone.0104396  1
2014 Bunyavanich S, Schadt EE, Himes BE, Lasky-Su J, Qiu W, Lazarus R, Ziniti JP, Cohain A, Linderman M, Torgerson DG, Eng CS, Pino-Yanes M, Padhukasahasram B, Yang JJ, Mathias RA, et al. Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis. Bmc Medical Genomics. 7: 48. PMID 25085501 DOI: 10.1186/1755-8794-7-48  1
2014 Stoffel EM, Eng C. Exome sequencing in familial colorectal cancer: Searching for needles in haystacks Gastroenterology. 147: 554-556. PMID 25075943 DOI: 10.1053/J.Gastro.2014.07.031  1
2014 Morris V, Overman MJ, Jiang ZQ, Garrett C, Agarwal S, Eng C, Kee B, Fogelman D, Dasari A, Wolff R, Maru D, Kopetz S. Progression-free survival remains poor over sequential lines of systemic therapy in patients with BRAF-mutated colorectal cancer. Clinical Colorectal Cancer. 13: 164-71. PMID 25069797 DOI: 10.1016/j.clcc.2014.06.001  1
2014 Subbiah IM, Blackmon SH, Correa AM, Kee B, Vaporciyan AA, Swisher SG, Eng C. Preoperative chemotherapy prior to pulmonary metastasectomy in surgically resected primary colorectal carcinoma. Oncotarget. 5: 6584-93. PMID 25051371  1
2014 Ngeow J, Eng C. TERT and BRAF in thyroid cancer: teaming up for trouble. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 2683-4. PMID 25024083 DOI: 10.1200/Jco.2014.56.5614  1
2014 Morris VK, Lucas FA, Overman MJ, Eng C, Morelli MP, Jiang ZQ, Luthra R, Meric-Bernstam F, Maru D, Scheet P, Kopetz S, Vilar E. Clinicopathologic characteristics and gene expression analyses of non-KRAS 12/13, RAS-mutated metastatic colorectal cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 25: 2008-14. PMID 25009008 DOI: 10.1093/Annonc/Mdu252  1
2014 Ahmed S, Eng C. Optimal treatment strategies for anal cancer Current Treatment Options in Oncology. 15: 443-455. PMID 25008956 DOI: 10.1007/s11864-014-0298-0  1
2014 Lieu CH, Renfro LA, de Gramont A, Meyers JP, Maughan TS, Seymour MT, Saltz L, Goldberg RM, Sargent DJ, Eckhardt SG, Eng C. Association of age with survival in patients with metastatic colorectal cancer: analysis from the ARCAD Clinical Trials Program. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 2975-84. PMID 25002720 DOI: 10.1200/JCO.2013.54.9329  1
2014 Ngeow J, Eng C. BluepRINT for moderate-to-low penetrance cancer susceptibility genes needed: breast cancer and beyond. Cancer Discovery. 4: 762-3. PMID 25002613 DOI: 10.1158/2159-8290.Cd-14-0498  1
2014 Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, et al. A unified nomenclature and amino acid numbering for human PTEN. Science Signaling. 7: pe15. PMID 24985344 DOI: 10.1126/Scisignal.2005560  1
2014 Tedla M, Bežová M, Biró C, Tedlová E, Eng CY, Zeleník K. Intravascular papillary endothelial hyperplasia of larynx: case report and literature review of all head and neck cases. Otolaryngologia Polska = the Polish Otolaryngology. 68: 200-3. PMID 24981303 DOI: 10.1016/j.otpol.2014.03.002  1
2014 Busch RM, Najm I, Hermann BP, Eng C. Genetics of cognition in epilepsy. Epilepsy & Behavior : E&B. 41: 297-306. PMID 24973143 DOI: 10.1016/J.Yebeh.2014.05.026  1
2014 Wang Y, Roma A, Nolley R, Abdul-Karim F, Peehl DM, Eng C. Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma. Endocrine-Related Cancer. 21: 579-86. PMID 24972837 DOI: 10.1530/Erc-14-0148  1
2014 Gronwald J, Robidoux A, Kim-Sing C, Tung N, Lynch HT, Foulkes WD, Manoukian S, Ainsworth P, Neuhausen SL, Demsky R, Eisen A, Singer CF, Saal H, Senter L, Eng C, et al. Duration of tamoxifen use and the risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment. 146: 421-7. PMID 24951267 DOI: 10.1007/S10549-014-3026-3  1
2014 Moreno-Estrada A, Gignoux CR, Fernández-López JC, Zakharia F, Sikora M, Contreras AV, Acuña-Alonzo V, Sandoval K, Eng C, Romero-Hidalgo S, Ortiz-Tello P, Robles V, Kenny EE, Nuño-Arana I, Barquera-Lozano R, et al. Human genetics. The genetics of Mexico recapitulates Native American substructure and affects biomedical traits. Science (New York, N.Y.). 344: 1280-5. PMID 24926019 DOI: 10.1126/Science.1251688  1
2014 Van Cutsem E, Eng C, Nowara E, Swieboda-Sadlej A, Tebbutt NC, Mitchell E, Davidenko I, Stephenson J, Elez E, Prenen H, Deng H, Tang R, McCaffery I, Oliner KS, Chen L, et al. Randomized phase Ib/II trial of rilotumumab or ganitumab with panitumumab versus panitumumab alone in patients with wild-type KRAS metastatic colorectal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 4240-50. PMID 24919569 DOI: 10.1158/1078-0432.CCR-13-2752  1
2014 Moline J, Eng C. Equality in Lynch syndrome screening: Why should we hold patients with endometrial cancer to a different standard? Journal of Clinical Oncology. 32: 2277. PMID 24912902 DOI: 10.1200/Jco.2014.55.3602  1
2014 Rogers JE, Eng C. Cetuximab in Refractory Squamous Cell Carcinoma of the Anal Canal Journal of Gastrointestinal Cancer. 45: 198-200. PMID 24908401 DOI: 10.1007/s12029-014-9626-7  1
2014 Tan MH, Eng C. RE: Cowden syndrome and PTEN hamartoma tumor syndrome: Systematic review and revised diagnostic criteria Journal of the National Cancer Institute. 106. PMID 24899679 DOI: 10.1093/Jnci/Dju130  1
2014 Stechschulte LA, Wuescher L, Marino JS, Hill JW, Eng C, Hinds TD. Glucocorticoid receptor β stimulates Akt1 growth pathway by attenuation of PTEN. The Journal of Biological Chemistry. 289: 17885-94. PMID 24817119 DOI: 10.1074/Jbc.M113.544072  1
2014 Xia F, Bainbridge MN, Tan TY, Wangler MF, Scheuerle AE, Zackai EH, Harr MH, Sutton VR, Nalam RL, Zhu W, Nash M, Ryan MM, Yaplito-Lee J, Hunter JV, Deardorff MA, ... ... Eng CM, et al. De novo truncating mutations in AHDC1 in individuals with syndromic expressive language delay, hypotonia, and sleep apnea. American Journal of Human Genetics. 94: 784-9. PMID 24791903 DOI: 10.1016/J.Ajhg.2014.04.006  1
2014 Ngeow J, Stanuch K, Mester JL, Barnholtz-Sloan JS, Eng C. Second malignant neoplasms in patients with Cowden syndrome with underlying germline PTEN mutations. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 1818-24. PMID 24778394 DOI: 10.1200/Jco.2013.53.6656  1
2014 Castinetti F, Qi XP, Walz MK, Maia AL, Sansó G, Peczkowska M, Hasse-Lazar K, Links TP, Dvorakova S, Toledo RA, Mian C, Bugalho MJ, Wohllk N, Kollyukh O, Canu L, ... Eng C, et al. Outcomes of adrenal-sparing surgery or total adrenalectomy in phaeochromocytoma associated with multiple endocrine neoplasia type 2: an international retrospective population-based study. The Lancet. Oncology. 15: 648-55. PMID 24745698 DOI: 10.1016/S1470-2045(14)70154-8  1
2014 Ngeow J, Ni Y, Tohme R, Song Chen F, Bebek G, Eng C. Germline alterations in RASAL1 in Cowden syndrome patients presenting with follicular thyroid cancer and in individuals with apparently sporadic epithelial thyroid cancer. The Journal of Clinical Endocrinology and Metabolism. 99: E1316-21. PMID 24712574 DOI: 10.1210/Jc.2014-1225  1
2014 Mutter GL, Monte NM, Neuberg D, Ferenczy A, Eng C. Emergence, involution, and progression to carcinoma of mutant clones in normal endometrial tissues Cancer Research. 74: 2796-2802. PMID 24662919 DOI: 10.1158/0008-5472.Can-14-0108  1
2014 Eng CM, Pancheri FQ, Lieberman DE, Biewener AA, Dorfmann L. Directional differences in the biaxial material properties of fascia lata and the implications for fascia function. Annals of Biomedical Engineering. 42: 1224-37. PMID 24647722 DOI: 10.1007/S10439-014-0999-3  1
2014 Eng CM, Yang Y, Plon SE. Genetic diagnosis through whole-exome sequencing. The New England Journal of Medicine. 370: 1068. PMID 24620872 DOI: 10.1056/NEJMc1315908  1
2014 Heald B, Eng C. Time studies of the tasks associated with comprehensive cancer genetics counseling: Reply Jnccn Journal of the National Comprehensive Cancer Network. 12: 303. PMID 24616535 DOI: 10.6004/Jnccn.2014.0045  1
2014 Frazier TW, Thompson L, Youngstrom EA, Law P, Hardan AY, Eng C, Morris N. A twin study of heritable and shared environmental contributions to autism. Journal of Autism and Developmental Disorders. 44: 2013-25. PMID 24604525 DOI: 10.1007/S10803-014-2081-2  1
2014 Poole A, Urbanek C, Eng C, Schageman J, Jacobson S, O'Connor BP, Galanter JM, Gignoux CR, Roth LA, Kumar R, Lutz S, Liu AH, Fingerlin TE, Setterquist RA, Burchard EG, et al. Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease Journal of Allergy and Clinical Immunology. 133: 670-678.e12. PMID 24495433 DOI: 10.1016/J.Jaci.2013.11.025  1
2014 Haynes AB, You YN, Hu CY, Eng C, Kopetz ES, Rodriguez-Bigas MA, Skibber JM, Cantor SB, Chang GJ. Postoperative chemotherapy use after neoadjuvant chemoradiotherapy for rectal cancer: Analysis of Surveillance, Epidemiology, and End Results-Medicare data, 1998-2007. Cancer. 120: 1162-70. PMID 24474245 DOI: 10.1002/cncr.28545  1
2014 Tilot AK, Gaugler MK, Yu Q, Romigh T, Yu W, Miller RH, Frazier TW, Eng C. Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production. Human Molecular Genetics. 23: 3212-27. PMID 24470394 DOI: 10.1093/Hmg/Ddu031  1
2014 Kotsopoulos J, Lubinski J, Moller P, Lynch HT, Singer CF, Eng C, Neuhausen SL, Karlan B, Kim-Sing C, Huzarski T, Gronwald J, McCuaig J, Senter L, Tung N, Ghadirian P, et al. Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutation carriers. Breast Cancer Research and Treatment. 143: 579-86. PMID 24458845 DOI: 10.1007/S10549-013-2823-4  1
2014 Segelman M, Szydlowski J, Kinosian B, McNabney M, Raziano DB, Eng C, van Reenen C, Temkin-Greener H. Hospitalizations in the Program of All-Inclusive Care for the Elderly. Journal of the American Geriatrics Society. 62: 320-4. PMID 24417503 DOI: 10.1111/jgs.12637  1
2014 Smith M, Mester J, Eng C. How to spot heritable breast cancer: a primary care physician's guide. Cleveland Clinic Journal of Medicine. 81: 31-40. PMID 24391105 DOI: 10.3949/Ccjm.81A.13051  1
2014 Blackham AU, Swett K, Eng C, Sirintrapun J, Bergman S, Geisinger KR, Votanopoulos K, Stewart JH, Shen P, Levine EA. Perioperative systemic chemotherapy for appendiceal mucinous carcinoma peritonei treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Journal of Surgical Oncology. 109: 740-5. PMID 24375188 DOI: 10.1002/jso.23547  1
2014 Pancheri FQ, Eng CM, Lieberman DE, Biewener AA, Dorfmann L. A constitutive description of the anisotropic response of the fascia lata. Journal of the Mechanical Behavior of Biomedical Materials. 30: 306-23. PMID 24361935 DOI: 10.1016/J.Jmbbm.2013.12.002  1
2014 Wang Y, Yu Q, He X, Romigh T, Altemus J, Eng C. Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation. Molecular Cancer Therapeutics. 13: 517-27. PMID 24356815 DOI: 10.1158/1535-7163.Mct-13-0655  1
2014 Henderson CJ, Ngeow J, Collins MH, Martin LJ, Putnam PE, Abonia JP, Marsolo K, Eng C, Rothenberg ME. Increased prevalence of eosinophilic gastrointestinal disorders in pediatric PTEN hamartoma tumor syndromes. Journal of Pediatric Gastroenterology and Nutrition. 58: 553-60. PMID 24345843 DOI: 10.1097/Mpg.0000000000000253  1
2014 Das P, Eng C, Rodriguez-Bigas MA, Chang GJ, Skibber JM, You YN, Maru DM, Munsell MF, Clemons MV, Kopetz SE, Garrett CR, Shureiqi I, Delclos ME, Krishnan S, Crane CH. Preoperative radiation therapy with concurrent capecitabine, bevacizumab, and erlotinib for rectal cancer: a phase 1 trial. International Journal of Radiation Oncology, Biology, Physics. 88: 301-5. PMID 24315563 DOI: 10.1016/j.ijrobp.2013.10.034  1
2014 Yuzawa S, Eng CH, Katz L, Keasling JD. Enzyme analysis of the polyketide synthase leads to the discovery of a novel analog of the antibiotic α-lipomycin. The Journal of Antibiotics. 67: 199-201. PMID 24169801 DOI: 10.1038/Ja.2013.110  1
2014 Bausch B, Wellner U, Bausch D, Schiavi F, Barontini M, Sanso G, Walz MK, Peczkowska M, Weryha G, Dall'igna P, Cecchetto G, Bisogno G, Moeller LC, Bockenhauer D, Patocs A, ... ... Eng C, et al. Long-term prognosis of patients with pediatric pheochromocytoma. Endocrine-Related Cancer. 21: 17-25. PMID 24169644 DOI: 10.1530/Erc-13-0415  1
2014 Frazier TW, Youngstrom EA, Embacher R, Hardan AY, Constantino JN, Law P, Findling RL, Eng C. Demographic and clinical correlates of autism symptom domains and autism spectrum diagnosis. Autism : the International Journal of Research and Practice. 18: 571-82. PMID 24104512 DOI: 10.1177/1362361313481506  1
2014 Mathewson MA, Kwan A, Eng CM, Lieber RL, Ward SR. Comparison of rotator cuff muscle architecture between humans and other selected vertebrate species. The Journal of Experimental Biology. 217: 261-73. PMID 24072803 DOI: 10.1242/Jeb.083923  1
2014 Drake KA, Torgerson DG, Gignoux CR, Galanter JM, Roth LA, Huntsman S, Eng C, Oh SS, Yee SW, Lin L, Bustamante CD, Moreno-Estrada A, Sandoval K, Davis A, Borrell LN, et al. A genome-wide association study of bronchodilator response in Latinos implicates rare variants. The Journal of Allergy and Clinical Immunology. 133: 370-8. PMID 23992748 DOI: 10.1016/J.Jaci.2013.06.043  1
2014 Kumar AP, Loo SY, Shin SW, Tan TZ, Eng CB, Singh R, Putti TC, Ong CW, Salto-Tellez M, Goh BC, Park JI, Thiery JP, Pervaiz S, Clement MV. Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma. Antioxidants & Redox Signaling. 20: 2326-46. PMID 23964924 DOI: 10.1089/Ars.2013.5295  1
2014 Yao TC, Du G, Han L, Sun Y, Hu D, Yang JJ, Mathias R, Roth LA, Rafaels N, Thompson EE, Loisel DA, Anderson R, Eng C, Arruabarrena Orbegozo M, Young M, et al. Genome-wide association study of lung function phenotypes in a founder population. The Journal of Allergy and Clinical Immunology. 133: 248-55.e1-10. PMID 23932459 DOI: 10.1016/J.Jaci.2013.06.018  1
2014 Wiszniewska J, Bi W, Shaw C, Stankiewicz P, Kang SH, Pursley AN, Lalani S, Hixson P, Gambin T, Tsai CH, Bock HG, Descartes M, Probst FJ, Scaglia F, Beaudet AL, ... ... Eng C, et al. Combined array CGH plus SNP genome analyses in a single assay for optimized clinical testing. European Journal of Human Genetics : Ejhg. 22: 79-87. PMID 23695279 DOI: 10.1038/Ejhg.2013.77  1
2014 Hobert JA, Embacher R, Mester JL, Frazier TW, Eng C. Biochemical screening and PTEN mutation analysis in individuals with autism spectrum disorders and macrocephaly. European Journal of Human Genetics : Ejhg. 22: 273-6. PMID 23695273 DOI: 10.1038/Ejhg.2013.114  1
2014 Kelly CWP, Eng CY, Shahed Quraishi M. Open mini-incision parathyroidectomy for solitary parathyroid adenoma European Archives of Oto-Rhino-Laryngology. 271: 555-560. PMID 23653305 DOI: 10.1007/s00405-013-2443-y  1
2014 Mitchell MP, Abboud M, Eng C, Beddar AS, Krishnan S, Delclos ME, Crane CH, Das P. Intensity-modulated radiation therapy with concurrent chemotherapy for anal cancer: outcomes and toxicity American Journal of Clinical Oncology. 37: 461-466. PMID 23466576 DOI: 10.1097/COC.0b013e31827e52a3  1
2014 Ngeow J, Eng C. Whole-genome sequencing: Not yet making the clinical grade Personalized Medicine. 11: 471-475. DOI: 10.2217/pme.14.32  1
2014 Asih HM, Eng CK. Throughput and tester utilization improvement in the hard disk drive assembly line using hybrid simulation approach Advanced Science Letters. 20: 455-459. DOI: 10.1166/asl.2014.5336  1
2014 Eng CC, Ibrahim NA, Zainuddin N, Ariffin H, Yunus WMZW, Then YY. Enhancement of mechanical and dynamic mechanical properties of hydrophilic nanoclay reinforced polylactic acid/polycaprolactone/oil palm mesocarp fiber hybrid composites International Journal of Polymer Science. 2014. DOI: 10.1155/2014/715801  1
2014 Mahdi H, Woessner JR, Buechel M, Moline J, Eng C, Michener C, Rose PG. Outcome and response to neoadjuvant chemotherapy in patients with advanced stage Müllerian cancer in BRCA1/2 mutation-positive compared to mutation-negative women Gynecologic Oncology. 133: 86. DOI: 10.1016/J.Ygyno.2014.03.230  1
2014 Mahdi H, Mester JL, Nizialek E, Michener C, Eng C. Germline SDHB/C/D variation and KLLN promoter methylation in endometrial cancer patients with Cowden and Cowden-like syndrome Gynecologic Oncology. 133: 78. DOI: 10.1016/J.Ygyno.2014.03.210  1
2014 Mahdi H, Mester JL, Michener C, Eng C. Prevalence and clinical predictors of germline PTEN mutation in endometrial cancer patients with Cowden and Cowden-like syndrome Gynecologic Oncology. 133: 77-78. DOI: 10.1016/J.Ygyno.2014.03.209  1
2014 Eng C. Colours and Contrast: Ceramic Traditions in Chinese Architecture Colours and Contrast: Ceramic Traditions in Chinese Architecture. 1-349.  1
2014 Eng CC, Ibrahim NA, Zainuddin N, Ariffin H, Yunus WMZW. Compositional and morphological changes of chemical modified oil palm mesocarp fiber by alkaline bleaching and silane coupling agents Bioresources. 9: 5290-5301.  1
2014 Rogers JE, Crane CH, Das P, Delclos M, Spencer Gould M, Ohinata A, Malatek D, Eng C. Definitive chemoradiation in oligometastatic squamous cell carcinoma of the anal canal Gastrointestinal Cancer Research. 7: 65-68.  1
2013 Ngeow J, Nizialek E, Eng C. Into the eye of the storm: breast cancer's somatic mutation landscape points to DNA damage and repair. Translational Cancer Research. 2: 59-61. PMID 26613077 DOI: 10.21037/1116  1
2013 Ngeow J, Eng C. RASAL1 in thyroid cancer: wisdom from an old foe. Journal of the National Cancer Institute. 105: 1597-9. PMID 24136888 DOI: 10.1093/Jnci/Djt291  1
2013 Valentini A, Lubinski J, Byrski T, Ghadirian P, Moller P, Lynch HT, Ainsworth P, Neuhausen SL, Weitzel J, Singer CF, Olopade OI, Saal H, Lyonnet DS, Foulkes WD, Kim-Sing C, ... Eng C, et al. The impact of pregnancy on breast cancer survival in women who carry a BRCA1 or BRCA2 mutation. Breast Cancer Research and Treatment. 142: 177-85. PMID 24136669 DOI: 10.1007/S10549-013-2729-1  1
2013 Mester JL, Moore RA, Eng C. PTEN germline mutations in patients initially tested for other hereditary cancer syndromes: would use of risk assessment tools reduce genetic testing? The Oncologist. 18: 1083-90. PMID 24037976 DOI: 10.1634/Theoncologist.2013-0174  1
2013 Heald B, Gustafson S, Mester J, Arscott P, Lynch K, Moline J, Eng C. A time study of cancer genetic counselors using a genetic counselor-only patient care model versus a traditional combined genetic counselor plus medical geneticist care model. Journal of the National Comprehensive Cancer Network : Jnccn. 11: 1076-81. PMID 24029123 DOI: 10.6004/Jnccn.2013.0129  1
2013 Bausch B, Jilg C, Gläsker S, Vortmeyer A, Lützen N, Anton A, Eng C, Neumann HP. Renal cancer in von Hippel-Lindau disease and related syndromes. Nature Reviews. Nephrology. 9: 529-38. PMID 23897319 DOI: 10.1038/Nrneph.2013.144  1
2013 Hopman SM, Merks JH, de Borgie CA, Aalfs CM, Biesecker LG, Cole T, Eng C, Legius E, Maher ER, van Noesel MM, Verloes A, Viskochil DH, Wagner A, Weksberg R, Caron HN, et al. The development of a clinical screening instrument for tumour predisposition syndromes in childhood cancer patients. European Journal of Cancer (Oxford, England : 1990). 49: 3247-54. PMID 23855994 DOI: 10.1016/J.Ejca.2013.06.015  1
2013 Semple J, Metcalfe KA, Lynch HT, Kim-Sing C, Senter L, Pal T, Ainsworth P, Lubinski J, Tung N, Eng C, Gilchrist D, Blum J, Neuhausen SL, Singer CF, Ghadirian P, et al. International rates of breast reconstruction after prophylactic mastectomy in BRCA1 and BRCA2 mutation carriers. Annals of Surgical Oncology. 20: 3817-22. PMID 23740344 DOI: 10.1245/S10434-013-3040-4  1
2013 Ngeow J, Eng C. Population-based universal screening for Lynch syndrome: ready, set... How? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2527-9. PMID 23733783 DOI: 10.1200/Jco.2013.50.4373  1
2013 Farley MN, Schmidt LS, Mester JL, Peña-Llopis S, Pavia-Jimenez A, Christie A, Vocke CD, Ricketts CJ, Peterson J, Middelton L, Kinch L, Grishin N, Merino MJ, Metwalli AR, Xing C, ... Eng C, et al. A novel germline mutation in BAP1 predisposes to familial clear-cell renal cell carcinoma. Molecular Cancer Research : McR. 11: 1061-71. PMID 23709298 DOI: 10.1158/1541-7786.Mcr-13-0111  1
2013 Mester J, Eng C. When overgrowth bumps into cancer: the PTEN-opathies. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 163: 114-21. PMID 23613428 DOI: 10.1002/ajmg.c.31364  1
2013 Moline J, Mahdi H, Yang B, Biscotti C, Roma AA, Heald B, Rose PG, Michener C, Eng C. Implementation of tumor testing for lynch syndrome in endometrial cancers at a large academic medical center. Gynecologic Oncology. 130: 121-6. PMID 23612316 DOI: 10.1016/J.Ygyno.2013.04.022  1
2013 Mester J, Eng C. When Overgrowth Bumps Into Cancer: The PTEN-Opathies. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. PMID 23576530 DOI: 10.1002/J.1552-4876.2013.31364.X  1
2013 He X, Arrotta N, Radhakrishnan D, Wang Y, Romigh T, Eng C. Cowden syndrome-related mutations in PTEN associate with enhanced proteasome activity. Cancer Research. 73: 3029-40. PMID 23475934 DOI: 10.1158/0008-5472.Can-12-3811  1
2013 Busch RM, Chapin JS, Mester J, Ferguson L, Haut JS, Frazier TW, Eng C. Cognitive characteristics of PTEN hamartoma tumor syndromes. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 548-53. PMID 23470840 DOI: 10.1038/Gim.2013.1  1
2013 Zhang L, Orloff MS, Reber S, Li S, Zhao Y, Eng C. cgaTOH: extended approach for identifying tracts of homozygosity. Plos One. 8: e57772. PMID 23469237 DOI: 10.1371/Journal.Pone.0057772  1
2013 Nizialek EA, Peterson C, Mester JL, Downes-Kelly E, Eng C. Germline and somatic KLLN alterations in breast cancer dysregulate G2 arrest. Human Molecular Genetics. 22: 2451-61. PMID 23446638 DOI: 10.1093/Hmg/Ddt097  1
2013 Wang Y, He X, Yu Q, Eng C. Androgen receptor-induced tumor suppressor, KLLN, inhibits breast cancer growth and transcriptionally activates p53/p73-mediated apoptosis in breast carcinomas. Human Molecular Genetics. 22: 2263-72. PMID 23418309 DOI: 10.1093/Hmg/Ddt077  1
2013 Heald B, Plesec T, Liu X, Pai R, Patil D, Moline J, Sharp RR, Burke CA, Kalady MF, Church J, Eng C. Implementation of universal microsatellite instability and immunohistochemistry screening for diagnosing lynch syndrome in a large academic medical center. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 1336-40. PMID 23401454 DOI: 10.1200/Jco.2012.45.1674  1
2013 Ngeow J, Heald B, Rybicki LA, Orloff MS, Chen JL, Liu X, Yerian L, Willis J, Lehtonen HJ, Lehtonen R, Mester JL, Moline J, Burke CA, Church J, Aaltonen LA, Eng C, et al. Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps. Gastroenterology. 144: 1402-9, 1409.e1-5. PMID 23399955 DOI: 10.1053/J.Gastro.2013.02.001  1
2013 Wang Y, Radhakrishnan D, He X, Peehl DM, Eng C. Transcription factor KLLN inhibits tumor growth by AR suppression, induces apoptosis by TP53/TP73 stimulation in prostate carcinomas, and correlates with cellular differentiation. The Journal of Clinical Endocrinology and Metabolism. 98: E586-94. PMID 23386643 DOI: 10.1210/Jc.2012-3490  1
2013 Granados A, Eng C, Diaz A. Brothers with germline PTEN mutations and persistent hypoglycemia, macrocephaly, developmental delay, short stature, and coagulopathy. Journal of Pediatric Endocrinology & Metabolism : Jpem. 26: 137-41. PMID 23382303 DOI: 10.1515/Jpem-2012-0227  1
2013 Wu W, Bhagat TD, Yang X, Song JH, Cheng Y, Agarwal R, Abraham JM, Ibrahim S, Bartenstein M, Hussain Z, Suzuki M, Yu Y, Chen W, Eng C, Greally J, et al. Hypomethylation of noncoding DNA regions and overexpression of the long noncoding RNA, AFAP1-AS1, in Barrett's esophagus and esophageal adenocarcinoma. Gastroenterology. 144: 956-966.e4. PMID 23333711 DOI: 10.1053/J.Gastro.2013.01.019  1
2013 Manolio TA, Chisholm RL, Ozenberger B, Roden DM, Williams MS, Wilson R, Bick D, Bottinger EP, Brilliant MH, Eng C, Frazer KA, Korf B, Ledbetter DH, Lupski JR, Marsh C, et al. Implementing genomic medicine in the clinic: the future is here. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 258-67. PMID 23306799 DOI: 10.1097/01.Ogx.0000435523.89711.77  1
2013 Neumann HP, Jilg C, Bacher J, Nabulsi Z, Malinoc A, Hummel B, Hoffmann MM, Ortiz-Bruechle N, Glasker S, Pisarski P, Neeff H, Krämer-Guth A, Cybulla M, Hornberger M, Wilpert J, ... Eng C, et al. Epidemiology of autosomal-dominant polycystic kidney disease: an in-depth clinical study for south-western Germany. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 28: 1472-87. PMID 23300259 DOI: 10.1093/Ndt/Gfs551  1
2013 Orloff MS, He X, Peterson C, Chen F, Chen JL, Mester JL, Eng C. Germline PIK3CA and AKT1 mutations in Cowden and Cowden-like syndromes. American Journal of Human Genetics. 92: 76-80. PMID 23246288 DOI: 10.1016/J.Ajhg.2012.10.021  1
2013 Ngeow J, Eng C. The 'in-vironment': Coming of age of microbiomics in personalized medicine Personalized Medicine. 10: 231-233. DOI: 10.2217/pme.13.15  1
2012 Milas M, Mester J, Metzger R, Shin J, Mitchell J, Berber E, Siperstein AE, Eng C. Should patients with Cowden syndrome undergo prophylactic thyroidectomy? Surgery. 152: 1201-10. PMID 23158187 DOI: 10.1016/J.Surg.2012.08.055  1
2012 Neumann HP, Malinoc A, Bacher J, Nabulsi Z, Ivanovas V, Bruechle NO, Mader I, Hoffmann MM, Riegler P, Kraemer-Guth A, Burchardi C, Schaeffner E, Martin RS, Azurmendi PJ, Zerres K, ... Eng C, et al. Characteristics of intracranial aneurysms in the else kröner-fresenius registry of autosomal dominant polycystic kidney disease. Cerebrovascular Diseases Extra. 2: 71-9. PMID 23139683 DOI: 10.1159/000342620  1
2012 Lewis CM, Bu D, Sarode V, Robinson L, Wilson KS, Viscusi RK, Eng C, Euhus DM. The clinical consequences of hemizygosity across 2 MB of 10q23 are restricted to Cowden syndrome. Breast Cancer Research and Treatment. 136: 911-8. PMID 23132533 DOI: 10.1007/S10549-012-2322-Z  1
2012 Ngeow J, He X, Mester JL, Lei J, Romigh T, Orloff MS, Milas M, Eng C. Utility of PTEN protein dosage in predicting for underlying germline PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypes. The Journal of Clinical Endocrinology and Metabolism. 97: E2320-7. PMID 23066114 DOI: 10.1210/Jc.2012-2944  1
2012 He X, Saji M, Radhakrishnan D, Romigh T, Ngeow J, Yu Q, Wang Y, Ringel MD, Eng C. PTEN lipid phosphatase activity and proper subcellular localization are necessary and sufficient for down-regulating AKT phosphorylation in the nucleus in Cowden syndrome. The Journal of Clinical Endocrinology and Metabolism. 97: E2179-87. PMID 22962422 DOI: 10.1210/Jc.2012-1991  1
2012 Ni Y, Eng C. Vitamin E protects against lipid peroxidation and rescues tumorigenic phenotypes in cowden/cowden-like patient-derived lymphoblast cells with germline SDHx variants Clinical Cancer Research. 18: 4954-4961. PMID 22829200 DOI: 10.1158/1078-0432.Ccr-12-1055  1
2012 O'Malley M, LaGuardia L, Kalady MF, Parambil J, Heald B, Eng C, Church J, Burke CA. The prevalence of hereditary hemorrhagic telangiectasia in juvenile polyposis syndrome. Diseases of the Colon and Rectum. 55: 886-92. PMID 22810475 DOI: 10.1097/Dcr.0B013E31825Aad32  1
2012 Mester J, Eng C. Estimate of de novo mutation frequency in probands with PTEN hamartoma tumor syndrome Genetics in Medicine. 14: 819-822. PMID 22595938 DOI: 10.1038/Gim.2012.51  1
2012 Kotsopoulos J, Lubinski J, Lynch HT, Kim-Sing C, Neuhausen S, Demsky R, Foulkes WD, Ghadirian P, Tung N, Ainsworth P, Senter L, Karlan B, Eisen A, Eng C, Weitzel J, et al. Oophorectomy after menopause and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers Cancer Epidemiology Biomarkers and Prevention. 21: 1089-1096. PMID 22564871 DOI: 10.1158/1055-9965.Epi-12-0201  1
2012 Doerr M, Eng C. Personalised care and the genome Bmj (Clinical Research Ed.). 344. PMID 22556053 DOI: 10.1136/Bmj.E3174  1
2012 Teng KA, Eng C. Personalizing patient care Cleveland Clinic Journal of Medicine. 79: 329-330. PMID 22550074 DOI: 10.3949/Ccjm.79A.11074  1
2012 Deschamps AM, Eng C. Engaging basic scientists in translational research. Endocrine-Related Cancer. 19: E1-3. PMID 22514111 DOI: 10.1530/Erc-12-0106  1
2012 Singh AD, Aronow ME, Sun Y, Bebek G, Saunthararajah Y, Schoenfield LR, Biscotti CV, Tubbs RR, Triozzi PL, Eng C. Chromosome 3 status in uveal melanoma: a comparison of fluorescence in situ hybridization and single-nucleotide polymorphism array. Investigative Ophthalmology & Visual Science. 53: 3331-9. PMID 22511634 DOI: 10.1167/Iovs.11-9027  1
2012 Hobin JA, Deschamps AM, Bockman R, Cohen S, Dechow P, Eng C, Galey W, Morris M, Prabhakar S, Raj U, Rubenstein P, Smith JA, Stover P, Sung N, Talman W, et al. Engaging basic scientists in translational research: identifying opportunities, overcoming obstacles. Journal of Translational Medicine. 10: 72. PMID 22500917 DOI: 10.1186/1479-5876-10-72  1
2012 Teng K, Eng C, Hess CA, Holt MA, Moran RT, Sharp RR, Traboulsi EI. Building an innovative model for personalized healthcare. Cleveland Clinic Journal of Medicine. 79: S1-9. PMID 22492701 DOI: 10.3949/Ccjm.79.S1.01  1
2012 Hesson LB, Packham D, Pontzer E, Funchain P, Eng C, Ward RL. A reinvestigation of somatic hypermethylation at the PTEN CpG island in cancer cell lines. Biological Procedures Online. 14: 5. PMID 22490388 DOI: 10.1186/1480-9222-14-5  1
2012 Tuupanen S, Yan J, Turunen M, Gylfe AE, Kaasinen E, Li L, Eng C, Culver DA, Kalady MF, Pennison MJ, Pasche B, Manne U, de la Chapelle A, Hampel H, Henderson BE, et al. Characterization of the colorectal cancer-associated enhancer MYC-335 at 8q24: the role of rs67491583. Cancer Genetics. 205: 25-33. PMID 22429595 DOI: 10.1016/J.Cancergen.2012.01.005  1
2012 Kotsopoulos J, Lubinski J, Salmena L, Lynch HT, Kim-Sing C, Foulkes WD, Ghadirian P, Neuhausen SL, Demsky R, Tung N, Ainsworth P, Senter L, Eisen A, Eng C, Singer C, et al. Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers Breast Cancer Research. 14. PMID 22405187 DOI: 10.1186/Bcr3138  1
2012 Mester JL, Zhou M, Prescott N, Eng C. Papillary Renal Cell Carcinoma is Associated with PTEN Hamartoma Tumor Syndrome Urology. 79: 1187. PMID 22381246 DOI: 10.1016/J.Urology.2011.12.025  1
2012 Malinoc A, Sullivan M, Wiech T, Kurt Werner S, Jilg C, Straeter J, Deger S, Hoffmann MM, Bosse A, Rasp G, Eng C, Neumann HP. Biallelic inactivation of the SDHC gene in renal carcinoma associated with paraganglioma syndrome type 3. Endocrine-Related Cancer. 19: 283-90. PMID 22351710 DOI: 10.1530/Erc-11-0324  1
2012 Ashida S, Orloff MS, Bebek G, Zhang L, Zheng P, Peehl DM, Eng C. Integrated analysis reveals critical genomic regions in prostate tumor microenvironment associated with clinicopathologic phenotypes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 1578-87. PMID 22275508 DOI: 10.1158/1078-0432.Ccr-11-2535  1
2012 Heindl M, Hndel N, Ngeow J, Kionke J, Wittekind C, Kamprad M, Rensing-Ehl A, Ehl S, Reifenberger J, Loddenkemper C, Maul J, Hoffmeister A, Aretz S, Kiess W, Eng C, et al. Autoimmunity, intestinal lymphoid hyperplasia, and defects in mucosal B-cell homeostasis in patients with PTEN hamartoma tumor syndrome Gastroenterology. 142: 1093-1096.e6. PMID 22266152 DOI: 10.1053/J.Gastro.2012.01.011  1
2012 Hobert JA, Mester JL, Moline J, Eng C. Elevated plasma succinate in PTEN, SDHB, and SDHD mutation-positive individuals. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 14: 616-9. PMID 22261759 DOI: 10.1038/Gim.2011.63  1
2012 Tan MH, Mester JL, Ngeow J, Rybicki LA, Orloff MS, Eng C. Lifetime cancer risks in individuals with germline PTEN mutations. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 400-7. PMID 22252256 DOI: 10.1158/1078-0432.Ccr-11-2283  1
2012 Heald B, Edelman E, Eng C. Prospective comparison of family medical history with personal genome screening for risk assessment of common cancers. European Journal of Human Genetics : Ejhg. 20: 547-51. PMID 22215421 DOI: 10.1038/Ejhg.2011.224  1
2012 Bebek G, Bennett KL, Funchain P, Campbell R, Seth R, Scharpf J, Burkey B, Eng C. Microbiomic subprofiles and MDR1 promoter methylation in head and neck squamous cell carcinoma. Human Molecular Genetics. 21: 1557-65. PMID 22180460 DOI: 10.1093/Hmg/Ddr593  1
2012 Frazier TW, Youngstrom EA, Speer L, Embacher R, Law P, Constantino J, Findling RL, Hardan AY, Eng C. Validation of proposed DSM-5 criteria for autism spectrum disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 51: 28-40.e3. PMID 22176937 DOI: 10.1016/J.Jaac.2011.09.021  1
2012 Wang Y, He X, Ngeow J, Eng C. GATA2 negatively regulates PTEN by preventing nuclear translocation of androgen receptor and by androgen-independent suppression of PTEN transcription in breast cancer. Human Molecular Genetics. 21: 569-76. PMID 22021428 DOI: 10.1093/Hmg/Ddr491  1
2012 Ni Y, He X, Chen J, Moline J, Mester J, Orloff MS, Ringel MD, Eng C. Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53. Human Molecular Genetics. 21: 300-10. PMID 21979946 DOI: 10.1093/Hmg/Ddr459  1
2012 Tan MH, De S, Bebek G, Orloff MS, Wesolowski R, Downs-Kelly E, Budd GT, Stark GR, Eng C. Specific kinesin expression profiles associated with taxane resistance in basal-like breast cancer. Breast Cancer Research and Treatment. 131: 849-58. PMID 21479552 DOI: 10.1007/S10549-011-1500-8  1
2012 Ngeow J, Eng C. Thyroid cancer genetics: How close are we to personalizing clinical management? Personalized Medicine. 9: 355-358. DOI: 10.2217/pme.12.31  1
2012 Ngeow J, Eng C. PTEN mutations: Help spot thyroid cancer before it occurs Expert Review of Endocrinology and Metabolism. 7: 251-254. DOI: 10.1586/Eem.12.15  1
2012 Funchain P, Bebek G, Bennett KL, Burkey B, Eng C. Correlation of microbiomic profiles with disease status and MDR1 methylation in head and neck squamous cell carcinoma (HNSCC). Journal of Clinical Oncology. 30: 5573-5573. DOI: 10.1200/Jco.2012.30.15_Suppl.5573  1
2012 Mester J, Moore R, Eng C. PTEN germline mutations in patients first tested for other hereditary cancer syndromes: Would use of risk assessment tools have reduced health care costs? Journal of Clinical Oncology. 30: 1516-1516. DOI: 10.1200/Jco.2012.30.15_Suppl.1516  1
2012 Ngeow JYY, He X, Mester J, Radhakrishnan D, Lei J, Romigh T, Milas M, Eng C. Use of PTEN protein dosage to predict for underlying germ-line PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypes. Journal of Clinical Oncology. 30: 1508-1508. DOI: 10.1200/Jco.2012.30.15_Suppl.1508  1
2012 Wang Y, He X, Eng C. Abstract 4855: KLLN, which shares a bidirectional promoter with PTEN, is an AR-regulated tumor suppressor, and induces p53-dependent and -independent apoptosis in breast cancer Cancer Research. 72: 4855-4855. DOI: 10.1158/1538-7445.Am2012-4855  1
2012 Bebek G, Bennett KL, Funchain P, Campbell R, Seth R, Scharpf J, Burkey B, Eng C. Abstract 4087: Microbiomic subprofiles and MDR1 promoter methylation in head and neck squamous cell carcinoma Cancer Research. 72: 4087-4087. DOI: 10.1158/1538-7445.Am2012-4087  1
2012 Ni Y, Eng C. Abstract 1120: α-Tocopherol protects cells from lipid peroxidation and rescues tumorigenic phenotypes in CS/CSL patients with germline SDHx variants Cancer Research. 72: 1120-1120. DOI: 10.1158/1538-7445.Am2012-1120  1
2012 Tan MH, Mester J, Eng C. Lifetime Cancer Risks of PTEN Mutation Carriers—Response Clinical Cancer Research. 18: 4214-4214. DOI: 10.1158/1078-0432.Ccr-12-1128  1
2012 Mester J, Escobar P, Roma A, Eng C. Risk for endometrial carcinoma, ovarian tumors and other gynecologic diagnoses in a prospective series of women with cowden syndrome and germline PTEN mutation Gynecologic Oncology. 125. DOI: 10.1016/J.Ygyno.2011.12.075  1
2011 Levi Z, Baris HN, Kedar I, Niv Y, Geller A, Gal E, Gingold R, Morgenstern S, Baruch Y, Leach BH, Bronner MP, Eng C. Upper and Lower Gastrointestinal Findings in PTEN Mutation-Positive Cowden Syndrome Patients Participating in an Active Surveillance Program. Clinical and Translational Gastroenterology. 2: e5. PMID 23238744 DOI: 10.1038/Ctg.2011.4  1
2011 Moline J, Ngeow J, Rajiah P, Eng C. Evil lurks in the heart of man: cardiac paraganglioma presenting as recurrent dyspnoea and chronic cough Case Reports. 2011. PMID 22670000 DOI: 10.1136/Bcr.11.2011.5170  1
2011 Ngeow J, Mester J, Rybicki LA, Ni Y, Milas M, Eng C. Incidence and clinical characteristics of thyroid cancer in prospective series of individuals with Cowden and Cowden-like syndrome characterized by germline PTEN, SDH, or KLLN alterations. The Journal of Clinical Endocrinology and Metabolism. 96: E2063-71. PMID 21956414 DOI: 10.1210/Jc.2011-1616  1
2011 Sullivan M, Rybicki LA, Winter A, Hoffmann MM, Reiermann S, Linke H, Arbeiter K, Patzer L, Budde K, Hoppe B, Zeier M, Lhotta K, Bock A, Wiech T, Gaspert A, ... Eng C, et al. Age-related penetrance of hereditary atypical hemolytic uremic syndrome. Annals of Human Genetics. 75: 639-47. PMID 21906045 DOI: 10.1111/J.1469-1809.2011.00671.X  1
2011 Bebek G, Orloff M, Eng C. Microenvironmental genomic alterations reveal signaling networks for head and neck squamous cell carcinoma. Journal of Clinical Bioinformatics. 1: 21-21. PMID 21884569 DOI: 10.1186/2043-9113-1-21  1
2011 Sharp RR, Goldlust ME, Eng C. Addressing gaps in physician education using personal genomic testing. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 13: 750-1. PMID 21814069 DOI: 10.1097/Gim.0B013E318228821F  1
2011 Orloff M, Peterson C, He X, Ganapathi S, Heald B, Yang YR, Bebek G, Romigh T, Song JH, Wu W, David S, Cheng Y, Meltzer SJ, Eng C. Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma. Jama. 306: 410-9. PMID 21791690 DOI: 10.1001/Jama.2011.1029  1
2011 Neumann HP, Sullivan M, Winter A, Malinoc A, Hoffmann MM, Boedeker CC, Bertz H, Walz MK, Moeller LC, Schmid KW, Eng C. Germline mutations of the TMEM127 gene in patients with paraganglioma of head and neck and extraadrenal abdominal sites. The Journal of Clinical Endocrinology and Metabolism. 96: E1279-82. PMID 21613359 DOI: 10.1210/Jc.2011-0114  1
2011 Bennett KL, Campbell R, Ganapathi S, Zhou M, Rini B, Ganapathi R, Neumann HP, Eng C. Germline and somatic DNA methylation and epigenetic regulation of KILLIN in renal cell carcinoma. Genes, Chromosomes & Cancer. 50: 654-61. PMID 21584899 DOI: 10.1002/Gcc.20887  1
2011 Moline J, Eng C. Multiple endocrine neoplasia type 2: An overview Genetics in Medicine. 13: 755-764. PMID 21552134 DOI: 10.1097/Gim.0B013E318216Cc6D  1
2011 Wang Y, Romigh T, He X, Tan MH, Orloff MS, Silverman RH, Heston WD, Eng C. Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers Oncogene. 30: 4327-4338. PMID 21532617 DOI: 10.1038/Onc.2011.144  1
2011 Nagy R, Ganapathi S, Comeras I, Peterson C, Orloff M, Porter K, Eng C, Ringel MD, Kloos RT. Frequency of germline PTEN mutations in differentiated thyroid cancer. Thyroid : Official Journal of the American Thyroid Association. 21: 505-10. PMID 21417916 DOI: 10.1089/Thy.2010.0365  1
2011 Tan MH, Eng C. Testicular microlithiasis: Recent advances in understanding and management Nature Reviews Urology. 8: 153-163. PMID 21394177 DOI: 10.1038/Nrurol.2011.1  1
2011 Mester JL, Tilot AK, Rybicki LA, Frazier TW, Eng C. Analysis of prevalence and degree of macrocephaly in patients with germline PTEN mutations and of brain weight in Pten knock-in murine model. European Journal of Human Genetics : Ejhg. 19: 763-8. PMID 21343951 DOI: 10.1038/Ejhg.2011.20  1
2011 Eng C. Something old, something new Endocrine-Related Cancer. 18. PMID 21212159 DOI: 10.1677/ERC-10-0324  1
2011 Tan MH, Mester J, Peterson C, Yang Y, Chen JL, Rybicki LA, Milas K, Pederson HJ, Remzi B, Orloff MS, Eng C. A Clinical Scoring System for Selection of Patients for PTEN Mutation Testing Is Proposed on the Basis of a Prospective Study of 3042 Probands American Journal of Human Genetics. 88: 42-56. PMID 21194675 DOI: 10.1016/J.Ajhg.2010.11.013  1
2011 von Dücker L, Walz MK, Voss C, Arnold G, Eng C, Neumann HP. Laparoscopic organ-sparing resection of von Hippel-Lindau disease-associated pancreatic neuroendocrine tumors. World Journal of Surgery. 35: 563-7. PMID 21181474 DOI: 10.1007/S00268-010-0878-5  1
2011 He X, Wang Y, Zhu J, Orloff M, Eng C. Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling. Cancer Letters. 301: 168-76. PMID 21168265 DOI: 10.1016/J.Canlet.2010.11.012  1
2011 Frank-Raue K, Rybicki LA, Erlic Z, Schweizer H, Winter A, Milos I, Toledo SP, Toledo RA, Tavares MR, Alevizaki M, Mian C, Siggelkow H, Hüfner M, Wohllk N, Opocher G, ... Eng C, et al. Risk profiles and penetrance estimations in multiple endocrine neoplasia type 2A caused by germline RET mutations located in exon 10. Human Mutation. 32: 51-8. PMID 20979234 DOI: 10.1002/Humu.21385  1
2011 Heald B, Eng C. Comparison of family health history to personal genomic screening for risk assessment of colon cancer Hereditary Cancer in Clinical Practice. 9: 1-1. DOI: 10.1186/1897-4287-9-S1-O2  1
2011 Ni Y, Eng C. Response to bayley: Functional study informs bioinformatic analysis American Journal of Human Genetics. 88: 676. DOI: 10.1016/J.Ajhg.2011.03.020  1
2010 Bennett KL, Mester J, Eng C. Germline epigenetic regulation of KILLIN in Cowden and Cowden-like syndrome. Jama. 304: 2724-31. PMID 21177507 DOI: 10.1001/Jama.2010.1877  1
2010 Eng C. Mendelian genetics of rare-and not so rare-cancers Annals of the New York Academy of Sciences. 1214: 70-82. PMID 20946573 DOI: 10.1111/J.1749-6632.2010.05789.X  1
2010 Erlic Z, Ploeckinger U, Cascon A, Hoffmann MM, von Duecker L, Winter A, Kammel G, Bacher J, Sullivan M, Isermann B, Fischer L, Raffel A, Knoefel WT, Schott M, Baumann T, ... Eng C, et al. Systematic comparison of sporadic and syndromic pancreatic islet cell tumors. Endocrine-Related Cancer. 17: 875-83. PMID 20660572 DOI: 10.1677/Erc-10-0037  1
2010 Heald B, Mester J, Rybicki L, Orloff MS, Burke CA, Eng C. Frequent gastrointestinal polyps and colorectal adenocarcinomas in a prospective series of PTEN mutation carriers Gastroenterology. 139: 1927-1933. PMID 20600018 DOI: 10.1053/J.Gastro.2010.06.061  1
2010 Hansel DE, Platt E, Orloff M, Harwalker J, Sethu S, Hicks JL, De Marzo A, Steinle RE, Hsi ED, Theodorescu D, Ching CB, Eng C. Mammalian target of rapamycin (mTOR) regulates cellular proliferation and tumor growth in urothelial carcinoma. The American Journal of Pathology. 176: 3062-72. PMID 20395440 DOI: 10.2353/Ajpath.2010.090872  1
2010 Eng C, Sharp RR. Bioethical and clinical dilemmas of direct-to-consumer personal genomic testing: the problem of misattributed equivalence. Science Translational Medicine. 2: 17cm5. PMID 20371476 DOI: 10.1126/Scitranslmed.3000214  1
2010 Shiovitz S, Everett J, Huang SC, Orloff MS, Eng C, Gruber SB. Head circumference in the clinical detection of PTEN hamartoma tumor syndrome in a clinic population at high-risk of breast cancer. Breast Cancer Research and Treatment. 124: 459-65. PMID 20349131 DOI: 10.1007/S10549-010-0839-6  1
2010 Eng C. Common alleles of predisposition in endocrine neoplasia Current Opinion in Genetics and Development. 20: 251-256. PMID 20211557 DOI: 10.1016/J.Gde.2010.02.004  1
2010 Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen HZ, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Wang D, Sadee W, La Perle K, Stromberg P, ... Eng C, et al. Allele-specific tumor spectrum in pten knockin mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 5142-7. PMID 20194734 DOI: 10.1073/Pnas.0912524107  1
2010 Frazier TW, Youngstrom EA, Sinclair L, Kubu CS, Law P, Rezai A, Constantino JN, Eng C. Autism spectrum disorders as a qualitatively distinct category from typical behavior in a large, clinically ascertained sample. Assessment. 17: 308-20. PMID 20040725 DOI: 10.1177/1073191109356534  1
2010 Erlic Z, Hoffmann MM, Sullivan M, Franke G, Peczkowska M, Harsch I, Schott M, Gabbert HE, Valimäki M, Preuss SF, Hasse-Lazar K, Waligorski D, Robledo M, Januszewicz A, Eng C, et al. Pathogenicity of DNA variants and double mutations in multiple endocrine neoplasia type 2 and von Hippel-Lindau syndrome. The Journal of Clinical Endocrinology and Metabolism. 95: 308-13. PMID 19906784 DOI: 10.1210/Jc.2009-1728  1
2010 Kirches E, Steiner J, Schneider T, Vorwerk CK, Scherlach C, Holtkamp N, Keilhoff G, Eng C, Mawrin C. Lhermitte-Duclos disease caused by a novel germline PTEN mutation R173P in a patient presenting with psychosis. Neuropathology and Applied Neurobiology. 36: 86-9. PMID 19719509 DOI: 10.1111/J.1365-2990.2009.01041.X  1
2010 Heald B, Mester J, Eng C. Gastrointestinal polyposis and PTEN mutations: an under-acknowledged diagnostic criterion Hereditary Cancer in Clinical Practice. 8: 1-1. DOI: 10.1186/1897-4287-8-S1-O3  1
2010 Bennett KL, Romigh T, Lee W, Lamarre E, Zhang X, Seth R, Scharpf J, Hunt J, Eng C. Abstract 4911: HPV-independent methylation of specific TGF-B pathway-relevant genes in head and neck squamous cell carcinomas associated with prior radiation therapy and exposure to alcohol and tobacco Cancer Research. 70: 4911-4911. DOI: 10.1158/1538-7445.Am10-4911  1
2010 Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen H, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Perle KL, Stromberg P, Rosol TJ, Eng C, et al. Abstract 3260: Allele-specific tumor spectrum inPtenknockin mice Cancer Research. 70: 3260-3260. DOI: 10.1158/1538-7445.Am10-3260  1
2010 Eng C. Robert J. Gorlin, DDS, MS (1923-2006): A geneticist for all seasons (Journal of Medical Genetics (2007) 44, (478-479) DOI: 10.1136/jmg.2006.048397) Journal of Medical Genetics. 47: 862. DOI: 10.1136/Jmg.2006.048397  1
2010 Edelman E, Eng C. PTEN Hamartoma Tumor Syndrome Management of Genetic Syndromes: Third Edition. 661-675. DOI: 10.1002/9780470893159.ch44  1
2009 Bennett KL, Romigh T, Eng C. Disruption of transforming growth factor-beta signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis. Cancer Research. 69: 9301-5. PMID 19934318 DOI: 10.1158/0008-5472.Can-09-3073  1
2009 Edelman E, Eng C. A practical guide to interpretation and clinical application of personal genomic screening. Bmj (Clinical Research Ed.). 339: b4253. PMID 19875427 DOI: 10.1136/Bmj.B4253  1
2009 Qian CN, Furge KA, Knol J, Huang D, Chen J, Dykema KJ, Kort EJ, Massie A, Khoo SK, Vanden Beldt K, Resau JH, Anema J, Kahnoski RJ, Morreau H, Camparo P, ... Eng C, et al. Activation of the PI3K/AKT pathway induces urothelial carcinoma of the renal pelvis: identification in human tumors and confirmation in animal models. Cancer Research. 69: 8256-64. PMID 19843858 DOI: 10.1158/0008-5472.Can-09-1689  1
2009 Erlic Z, Rybicki L, Peczkowska M, Golcher H, Kann PH, Brauckhoff M, Müssig K, Muresan M, Schäffler A, Reisch N, Schott M, Fassnacht M, Opocher G, Klose S, Fottner C, ... Eng C, et al. Clinical predictors and algorithm for the genetic diagnosis of pheochromocytoma patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6378-85. PMID 19825962 DOI: 10.1158/1078-0432.Ccr-09-1237  1
2009 Bennett KL, Romigh T, Eng C. AP-2alpha induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma. Plos One. 4: e6931. PMID 19742317 DOI: 10.1371/Journal.Pone.0006931  1
2009 Bekaii-Saab T, Markowitz J, Prescott N, Sadee W, Heerema N, Wei L, Dai Z, Papp A, Campbell A, Culler K, Balint C, O'Neil B, Lee RM, Zalupski M, Dancey J, ... Eng C, et al. A multi-institutional phase II study of the efficacy and tolerability of lapatinib in patients with advanced hepatocellular carcinomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5895-901. PMID 19737952 DOI: 10.1158/1078-0432.Ccr-09-0465  1
2009 Eng C, Leone G, Orloff MS, Ostrowski MC. Genomic alterations in tumor stroma. Cancer Research. 69: 6759-64. PMID 19706759 DOI: 10.1158/0008-5472.Can-09-0985  1
2009 Hobert JA, Eng C. PTEN hamartoma tumor syndrome: an overview. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 11: 687-94. PMID 19668082 DOI: 10.1097/Gim.0B013E3181Ac9Aea  1
2009 Neumann HPH, Eng C. The approach to the patient with paraganglioma Journal of Clinical Endocrinology and Metabolism. 94: 2677-2683. PMID 19657044 DOI: 10.1210/Jc.2009-0496  1
2009 Jacob AI, Romigh T, Waite KA, Eng C. Nuclear PTEN levels and G2 progression in melanoma cells. Melanoma Research. 19: 203-210. PMID 19478684 DOI: 10.1097/Cmr.0B013E32832Ccd6E  1
2009 Kloos RT, Eng C, Evans DB, Francis GL, Gagel RF, Gharib H, Moley JF, Pacini F, Ringel MD, Schlumberger M, Wells SA. Medullary thyroid cancer: management guidelines of the American Thyroid Association. Thyroid : Official Journal of the American Thyroid Association. 19: 565-612. PMID 19469690 DOI: 10.1089/Thy.2008.0403  1
2009 Lobo GP, Waite KA, Planchon SM, Romigh T, Nassif NT, Eng C. Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function. Human Molecular Genetics. 18: 2851-62. PMID 19457929 DOI: 10.1093/Hmg/Ddp220  1
2009 Neumann HP, Erlic Z, Boedeker CC, Rybicki LA, Robledo M, Hermsen M, Schiavi F, Falcioni M, Kwok P, Bauters C, Lampe K, Fischer M, Edelman E, Benn DE, Robinson BG, ... Eng C, et al. Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. Cancer Research. 69: 3650-6. PMID 19351833 DOI: 10.1158/0008-5472.Can-08-4057  1
2009 Boedeker CC, Erlic Z, Richard S, Kontny U, Gimenez-Roqueplo AP, Cascon A, Robledo M, de Campos JM, van Nederveen FH, de Krijger RR, Burnichon N, Gaal J, Walter MA, Reschke K, Wiech T, ... Eng C, et al. Head and neck paragangliomas in von Hippel-Lindau disease and multiple endocrine neoplasia type 2. The Journal of Clinical Endocrinology and Metabolism. 94: 1938-44. PMID 19336503 DOI: 10.1210/Jc.2009-0354  1
2009 Crouser ED, Culver DA, Knox KS, Julian MW, Shao G, Abraham S, Liyanarachchi S, Macre JE, Wewers MD, Gavrilin MA, Ross P, Abbas A, Eng C. Gene expression profiling identifies MMP-12 and ADAMDEC1 as potential pathogenic mediators of pulmonary sarcoidosis. American Journal of Respiratory and Critical Care Medicine. 179: 929-38. PMID 19218196 DOI: 10.1164/Rccm.200803-490Oc  1
2009 Lin MC, Lomo L, Baak JPA, Eng C, Ince TA, Crum CP, Mutter GL. Squamous morules are functionally inert elements of premalignant endometrial neoplasia Modern Pathology. 22: 167-174. PMID 19180120 DOI: 10.1038/Modpathol.2008.146  1
2009 Bennett KL, Romigh T, Arab K, Teresi RE, Tada Y, Eng C, Plass C. Activator protein 2 alpha (AP2alpha) suppresses 42 kDa C/CAAT enhancer binding protein alpha (p42(C/EBPalpha)) in head and neck squamous cell carcinoma. International Journal of Cancer. 124: 1285-92. PMID 19089912 DOI: 10.1002/Ijc.24087  1
2009 Orloff MS, Eng C. Genes Encoding Mitochondrial Enzyme Succinate Dehydrogenase Provide More Power for Breast Cancer Risk Assessment Breast Diseases: a Year Book Quarterly. 19: 298-302. DOI: 10.1016/S1043-321X(09)79232-X  1
2008 Eng C. Microenvironmental protection in diffuse large-B-cell lymphoma New England Journal of Medicine. 359: 2379-2381. PMID 19038884 DOI: 10.1056/Nejme0808409  1
2008 Eng C. Cancer: A ringleader identified Nature. 455: 883-884. PMID 18923503 DOI: 10.1038/455883A  1
2008 Peczkowska M, Erlic Z, Hoffmann MM, Furmanek M, Cwikla J, Kubaszek A, Prejbisz A, Szutkowski Z, Kawecki A, Chojnowski K, Lewczuk A, Litwin M, Szyfter W, Walter MA, Sullivan M, Eng C, et al. Impact of screening kindreds for SDHD p.Cys11X as a common mutation associated with paraganglioma syndrome type 1. The Journal of Clinical Endocrinology and Metabolism. 93: 4818-25. PMID 18826997 DOI: 10.1210/Jc.2008-1290  1
2008 Orloff MS, Eng C. Genetic and phenotypic heterogeneity in the PTEN hamartoma tumour syndrome Oncogene. 27: 5387-5397. PMID 18794875 DOI: 10.1038/Onc.2008.237  1
2008 Milos IN, Frank-Raue K, Wohllk N, Maia AL, Pusiol E, Patocs A, Robledo M, Biarnes J, Barontini M, Links TP, de Groot JW, Dvorakova S, Peczkowska M, Rybicki LA, Sullivan M, ... Eng C, et al. Age-related neoplastic risk profiles and penetrance estimations in multiple endocrine neoplasia type 2A caused by germ line RET Cys634Trp (TGC>TGG) mutation. Endocrine-Related Cancer. 15: 1035-41. PMID 18794325 DOI: 10.1677/Erc-08-0105  1
2008 Eng C. SDHB - A gene for all tumors? Journal of the National Cancer Institute. 100: 1193-1195. PMID 18728280 DOI: 10.1093/Jnci/Djn263  1
2008 Ni Y, Zbuk KM, Sadler T, Patocs A, Lobo G, Edelman E, Platzer P, Orloff MS, Waite KA, Eng C. Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes. American Journal of Human Genetics. 83: 261-8. PMID 18678321 DOI: 10.1016/J.Ajhg.2008.07.011  1
2008 Plon SE, Pirics ML, Nuchtern J, Hicks J, Russell H, Agrawal S, Zbuk K, Eng C, Hegde M, Chin EL. Multiple tumors in a child with germ-line mutations in TP53 and PTEN. The New England Journal of Medicine. 359: 537-9. PMID 18669439 DOI: 10.1056/Nejmc0800627  1
2008 Cho MY, Kim HS, Eng C, Kim DS, Kang SJ, Eom M, Yi SY, Bronner MP. First report of ovarian dysgerminoma in Cowden syndrome with germline PTEN mutation and PTEN-related 10q loss of tumor heterozygosity American Journal of Surgical Pathology. 32: 1258-1264. PMID 18594467 DOI: 10.1097/Pas.0B013E31816Be8B7  1
2008 Lobo GP, Waite KA, Planchon SM, Romigh T, Houghton JA, Eng C. ATP modulates PTEN subcellular localization in multiple cancer cell lines. Human Molecular Genetics. 17: 2877-85. PMID 18579579 DOI: 10.1093/Hmg/Ddn185  1
2008 Ahvenainen T, Lehtonen HJ, Lehtonen R, Vahteristo P, Aittomäki K, Baynam G, Dommering C, Eng C, Gruber SB, Grönberg H, Harvima R, Herva R, Hietala M, Kujala M, Kääriäinen H, et al. Mutation screening of fumarate hydratase by multiplex ligation-dependent probe amplification: detection of exonic deletion in a patient with leiomyomatosis and renal cell cancer Cancer Genetics and Cytogenetics. 183: 83-88. PMID 18503824 DOI: 10.1016/J.Cancergencyto.2008.01.010  1
2008 Pezzolesi MG, Platzer P, Waite KA, Eng C. Differential expression of PTEN-targeting microRNAs miR-19a and miR-21 in Cowden syndrome. American Journal of Human Genetics. 82: 1141-9. PMID 18460397 DOI: 10.1016/J.Ajhg.2008.04.005  1
2008 Weber F, Eng C. Update on the molecular diagnosis of endocrine tumors: Toward -omics-based personalized healthcare? Journal of Clinical Endocrinology and Metabolism. 93: 1097-1104. PMID 18390809 DOI: 10.1210/Jc.2008-0212  1
2008 Trimboli AJ, Fukino K, de Bruin A, Wei G, Shen L, Tanner SM, Creasap N, Rosol TJ, Robinson ML, Eng C, Ostrowski MC, Leone G. Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Research. 68: 937-45. PMID 18245497 DOI: 10.1158/0008-5472.Can-07-2148  1
2008 Peczkowska M, Cascon A, Prejbisz A, Kubaszek A, Cwikła BJ, Furmanek M, Erlic Z, Eng C, Januszewicz A, Neumann HPH. Extra-adrenal and adrenal pheochromocytomas associated with a germline SDHC mutation. Nature Clinical Practice Endocrinology & Metabolism. 4: 111-115. PMID 18212813 DOI: 10.1038/Ncpendmet0726  1
2008 Eng C. Interview: From high school dream to genomic medicine reality Personalized Medicine. 5: 569-573. DOI: 10.2217/17410541.5.6.569  1
2008 Chernausek SD, Eng CS. Pheochromocytoma and the Multiple Endocrine Neoplasia Syndromes Pediatric Endocrinology. 512-529. DOI: 10.1016/B978-141604090-3.50018-1  1
2007 Patocs A, Zhang L, Xu Y, Weber F, Caldes T, Mutter GL, Platzer P, Eng C. Breast-cancer stromal cells with TP53 mutations and nodal metastases. The New England Journal of Medicine. 357: 2543-51. PMID 18094375 DOI: 10.1056/Nejmoa071825  1
2007 Heald B, Moran R, Milas M, Burke C, Eng C. Familial adenomatous polyposis in a patient with unexplained mental retardation. Nature Reviews Neurology. 3: 694-700. PMID 18046442 DOI: 10.1038/Ncpneuro0658  1
2007 Neumann HPH, Vortmeyer A, Schmidt D, Werner M, Erlic Z, Cascon A, Bausch B, Januszewicz A, Eng C. Evidence of MEN-2 in the Original Description of Classic Pheochromocytoma The New England Journal of Medicine. 357: 1311-1315. PMID 17898100 DOI: 10.1056/Nejmoa071407  1
2007 Teresi RE, Zbuk KM, Pezzolesi MG, Waite KA, Eng C. Cowden syndrome-affected patients with PTEN promoter mutations demonstrate abnormal protein translation. American Journal of Human Genetics. 81: 756-67. PMID 17847000 DOI: 10.1086/521051  1
2007 Zbuk KM, Eng C. Hamartomatous polyposis syndromes Nature Clinical Practice Gastroenterology and Hepatology. 4: 492-502. PMID 17768394 DOI: 10.1038/Ncpgasthep0902  1
2007 Heald B, Hilden JM, Zbuk K, Norton A, Vyas P, Theil KS, Eng C. Severe TMD/AMKL with GATA1 mutation in a stillborn fetus with Down syndrome. Nature Clinical Practice. Oncology. 4: 433-8. PMID 17597708 DOI: 10.1038/Ncponc0876  1
2007 Ochs-Balcom HM, Falk G, Grady WM, Kinnard M, Willis J, Elston R, Eng C, Chak A. Consortium approach to identifying genes for Barrett's esophagus and esophageal adenocarcinoma. Translational Research : the Journal of Laboratory and Clinical Medicine. 150: 3-17. PMID 17585859 DOI: 10.1016/J.Trsl.2007.02.005  1
2007 Bennett KL, Hackanson B, Smith LT, Morrison CD, Lang JC, Schuller DE, Weber F, Eng C, Plass C. Tumor suppressor activity of CCAAT/enhancer binding protein alpha is epigenetically down-regulated in head and neck squamous cell carcinoma. Cancer Research. 67: 4657-64. PMID 17510391 DOI: 10.1158/0008-5472.Can-06-4793  1
2007 Fukino K, Shen L, Patocs A, Mutter GL, Eng C. Genomic instability within tumor stroma and clinicopathological characteristics of sporadic primary invasive breast carcinoma. Jama. 297: 2103-11. PMID 17507346 DOI: 10.1001/Jama.297.19.2103  1
2007 Bausch B, Borozdin W, Mautner VF, Hoffmann MM, Boehm D, Robledo M, Cascon A, Harenberg T, Schiavi F, Pawlu C, Peczkowska M, Letizia C, Calvieri S, Arnaldi G, Klingenberg-Noftz RD, ... Eng C, et al. Germline NF1 mutational spectra and loss-of-heterozygosity analyses in patients with pheochromocytoma and neurofibromatosis type 1. The Journal of Clinical Endocrinology and Metabolism. 92: 2784-92. PMID 17426081 DOI: 10.1210/Jc.2006-2833  1
2007 Pezzolesi MG, Zbuk KM, Waite KA, Eng C. Comparative genomic and functional analyses reveal a novel cis-acting PTEN regulatory element as a highly conserved functional E-box motif deleted in Cowden syndrome. Human Molecular Genetics. 16: 1058-71. PMID 17341483 DOI: 10.1093/Hmg/Ddm053  1
2007 Zbuk KM, Eng C. Predicting response to EGFR-tyrosine kinase inhibitors among diverse ancestries: Just 'way too polymorphic Cancer Biology and Therapy. 6: 112-115. PMID 17264670 DOI: 10.4161/Cbt.6.1.3787  1
2007 Kotsopoulos J, Lubinski J, Lynch HT, Klijn J, Ghadirian P, Neuhausen SL, Kim-Sing C, Foulkes WD, Moller P, Isaacs C, Domchek S, Randall S, Offit K, Tung N, Ainsworth P, ... Eng C, et al. Age at first birth and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment. 105: 221-8. PMID 17245541 DOI: 10.1007/S10549-006-9441-3  1
2007 Yee LD, Williams N, Wen P, Young DC, Lester J, Johnson MV, Farrar WB, Walker MJ, Povoski SP, Suster S, Eng C. Pilot study of rosiglitazone therapy in women with breast cancer: effects of short-term therapy on tumor tissue and serum markers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 246-52. PMID 17200362 DOI: 10.1158/1078-0432.Ccr-06-1947  1
2007 Zbuk KM, Eng C. Cancer phenomics: RET and PTEN as illustrative models Nature Reviews Cancer. 7: 35-45. PMID 17167516 DOI: 10.1038/Nrc2037  1
2006 Aldred MA, Eng C. SNP'ing at nasopharyngeal cancer susceptibility: For whom the bell tolls Cancer Biology and Therapy. 5: 1292-1293. PMID 17172806 DOI: 10.4161/Cbt.5.10.3487  1
2006 Yan PS, Venkataramu C, Ibrahim A, Liu JC, Shen RZ, Diaz NM, Centeno B, Weber F, Leu YW, Shapiro CL, Eng C, Yeatman TJ, Huang TH. Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6626-36. PMID 17121881 DOI: 10.1158/1078-0432.Ccr-06-0467  1
2006 Bausch B, Boedeker CC, Berlis A, Brink I, Cybulla M, Walz MK, Januszewicz A, Letizia C, Opocher G, Eng C, Neumann HPH. Genetic and clinical investigation of pheochromocytoma: a 22-year experience, from Freiburg, Germany to international effort. Annals of the New York Academy of Sciences. 1073: 122-137. PMID 17102079 DOI: 10.1196/Annals.1353.013  1
2006 Pezzolesi MG, Li Y, Zhou XP, Pilarski R, Shen L, Eng C. Mutation-positive and mutation-negative patients with Cowden and Bannayan-Riley-Ruvalcaba syndromes associated with distinct 10q haplotypes. American Journal of Human Genetics. 79: 923-34. PMID 17033968 DOI: 10.1086/508943  1
2006 Chak A, Ochs-Balcom H, Falk G, Grady WM, Kinnard M, Willis JE, Elston R, Eng C. Familiality in Barrett's esophagus, adenocarcinoma of the esophagus, and adenocarcinoma of the gastroesophageal junction Cancer Epidemiology Biomarkers and Prevention. 15: 1668-1673. PMID 16985029 DOI: 10.1158/1055-9965.Epi-06-0293  1
2006 Chung JH, Ostrowski MC, Romigh T, Minaguchi T, Waite KA, Eng C. The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation. Human Molecular Genetics. 15: 2553-9. PMID 16849370 DOI: 10.1093/Hmg/Ddl177  1
2006 Tang Y, Eng C. p53 down-regulates phosphatase and tensin homologue deleted on chromosome 10 protein stability partially through caspase-mediated degradation in cells with proteasome dysfunction Cancer Research. 66: 6139-6148. PMID 16778187 DOI: 10.1158/0008-5472.Can-06-0772  1
2006 Weber F, Shen L, Fukino K, Patocs A, Mutter GL, Caldes T, Eng C. Total-genome analysis of BRCA1/2-related invasive carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation. American Journal of Human Genetics. 78: 961-72. PMID 16685647 DOI: 10.1086/504090  1
2006 Lim LC, Tan MH, Eng C, Teh BT, Rajasoorya RC. Thymic carcinoid in multiple endocrine neoplasia 1: genotype–phenotype correlation and prevention Journal of Internal Medicine. 259: 428-432. PMID 16594911 DOI: 10.1111/J.1365-2796.2006.01619.X  1
2006 Friedman E, Kotsopoulos J, Lubinski J, Lynch HT, Ghadirian P, Neuhausen SL, Isaacs C, Weber B, Foulkes WD, Moller P, Rosen B, Kim-Sing C, Gershoni-Baruch R, Ainsworth P, Daly M, ... Eng C, et al. Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers. Breast Cancer Research : Bcr. 8: R15. PMID 16563180 DOI: 10.1186/Bcr1387  1
2006 Agrawal S, Eng C. Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer Human Molecular Genetics. 15: 777-787. PMID 16436456 DOI: 10.1093/Hmg/Ddi492  1
2006 Tang Y, Eng C. PTEN autoregulates its expression by stabilization of p53 in a phosphatase-independent manner Cancer Research. 66: 736-742. PMID 16424003 DOI: 10.1158/0008-5472.Can-05-1557  1
2006 Patterson AR, Leitch AM, Weatherall P, Zhou XP, Eng C, Tomlinson GE. Case 4. Fibrocystic breast disease in a 16-year-old female with PTEN hamartoma tumor syndrome Journal of Clinical Oncology. 24: 525-527. PMID 16421431 DOI: 10.1200/Jco.2004.01.0447  1
2006 Abdel-Rahman MH, Yang Y, Zhou XP, Craig EL, Davidorf FH, Eng C. High frequency of submicroscopic hemizygous deletion is a major mechanism of loss of expression of PTEN in uveal melanoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 288-95. PMID 16344319 DOI: 10.1200/Jco.2005.02.2418  1
2006 Perry CG, Young WF, McWhinney SR, Bei T, Stergiopoulos S, Knudson RA, Ketterling RP, Eng C, Stratakis CA, Carney JA. Functioning paraganglioma and gastrointestinal stromal tumor of the jejunum in three women: syndrome or coincidence. The American Journal of Surgical Pathology. 30: 42-9. PMID 16330941 DOI: 10.1097/01.Pas.0000178087.69394.9F  1
2006 Sarquis MS, Weber F, Shen L, Broelsch CE, Jhiang SM, Zedenius J, Frilling A, Eng C. High frequency of loss of heterozygosity in imprinted, compared with nonimprinted, genomic regions in follicular thyroid carcinomas and atypical adenomas. The Journal of Clinical Endocrinology and Metabolism. 91: 262-9. PMID 16249278 DOI: 10.1210/Jc.2005-1880  1
2006 Nkondjock A, Ghadirian P, Kotsopoulos J, Lubinski J, Lynch H, Kim-Sing C, Horsman D, Rosen B, Isaacs C, Weber B, Foulkes W, Ainsworth P, Tung N, Eisen A, Friedman E, Eng C, et al. Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers. International Journal of Cancer. 118: 103-7. PMID 16032702 DOI: 10.1002/Ijc.21296  1
2005 Eng C, Weber F. Gene-expression profiling in differentiated thyroid cancer - A viable strategy for the practice of genomic medicine? Future Oncology. 1: 497-510. PMID 16556026 DOI: 10.2217/14796694.1.4.497  1
2005 Eng C. Serendipity, fate, science and leadership Cancer Biology &Amp; Therapy.. 4: 1422-1425. PMID 16322685 DOI: 10.4161/Cbt.4.12.2336  1
2005 Sweet K, Willis J, Zhou XP, Gallione C, Sawada T, Alhopuro P, Khoo SK, Patocs A, Martin C, Bridgeman S, Heinz J, Pilarski R, Lehtonen R, Prior TW, Frebourg T, ... Eng C, et al. Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis. Jama. 294: 2465-73. PMID 16287957 DOI: 10.1001/Jama.294.19.2465  1
2005 Weber F, Eng C. Editorial: Germline variants within RET: Clinical utility or scientific playtoy? Journal of Clinical Endocrinology and Metabolism. 90: 6334-6336. PMID 16275981 DOI: 10.1210/Jc.2005-2030  1
2005 Schiavi F, Boedeker CC, Bausch B, Peçzkowska M, Gomez CF, Strassburg T, Pawlu C, Buchta M, Salzmann M, Hoffmann MM, Berlis A, Brink I, Cybulla M, Muresan M, Walter MA, ... Eng C, et al. Predictors and prevalence of paraganglioma syndrome associated with mutations of the SDHC gene. Jama. 294: 2057-63. PMID 16249420 DOI: 10.1001/Jama.294.16.2057  1
2005 Marsee DK, Vadysirisack DD, Morrison CD, Prasad ML, Eng C, Duh QY, Rauen KA, Kloos RT, Jhiang SM. Variable expression of coxsackie-adenovirus receptor in thyroid tumors: implications for adenoviral gene therapy. Thyroid : Official Journal of the American Thyroid Association. 15: 977-87. PMID 16187905 DOI: 10.1089/Thy.2005.15.977  1
2005 Chung JH, Eng C. Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis Cancer Research. 65: 8096-8100. PMID 16166282 DOI: 10.1158/0008-5472.Can-05-1888  1
2005 Eng C. High frequency of large gene deletions and rearrangements in Lynch syndrome-back to the future? Gastroenterology. 129: 1124-1126. PMID 16143150 DOI: 10.1053/J.Gastro.2005.07.043  1
2005 Fernandez RM, Boru G, Peciña A, Jones K, López-Alonso M, Antiñolo G, Borrego S, Eng C. Ancestral RET haplotype associated with Hirschsprung's disease shows linkage disequilibrium breakpoint at -1249. Journal of Medical Genetics. 42: 322-7. PMID 15805159 DOI: 10.1136/Jmg.2004.023960  1
2004 Hemminki K, Eng C. Clinical genetic counselling for familial cancers requires reliable data on familial cancer risks and general action plans Journal of Medical Genetics. 41: 801-807. PMID 15520403 DOI: 10.1136/Jmg.2004.022731  1
2004 Fukino K, Shen L, Matsumoto S, Morrison CD, Mutter GL, Eng C. Combined Total Genome Loss of Heterozygosity Scan of Breast Cancer Stroma and Epithelium Reveals Multiplicity of Stromal Targets Cancer Research. 64: 7231-7236. PMID 15492239 DOI: 10.1158/0008-5472.Can-04-2866  1
2004 Neumann HP, Pawlu C, Peczkowska M, Bausch B, McWhinney SR, Muresan M, Buchta M, Franke G, Klisch J, Bley TA, Hoegerle S, Boedeker CC, Opocher G, Schipper J, Januszewicz A, Eng C, et al. Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. Jama. 292: 943-51. PMID 15328326 DOI: 10.1001/Jama.292.8.943  1
2004 Eng C, Iglehart D. Decision aids from genetics to treatment of breast cancer: Long-term clinical utility or temporary solution? Journal of the American Medical Association. 292: 496-498. PMID 15280348 DOI: 10.1001/Jama.292.4.496  1
2004 Pilarski R, Eng C. Will the real Cowden syndrome please stand up (again)? Expanding mutational and clinical spectra of the PTEN hamartoma tumour syndrome Journal of Medical Genetics. 41: 323-326. PMID 15121767 DOI: 10.1136/Jmg.2004.018036  1
2004 Nassif NT, Lobo GP, Wu X, Henderson CJ, Morrison CD, Eng C, Jalaludin B, Segelov E. PTEN mutations are common in sporadic microsatellite stable colorectal cancer. Oncogene. 23: 617-28. PMID 14724591 DOI: 10.1038/Sj.Onc.1207059  1
2004 Vanharanta S, Buchta M, McWhinney SR, Virta SK, Peçzkowska M, Morrison CD, Lehtonen R, Januszewicz A, Järvinen H, Juhola M, Mecklin JP, Pukkala E, Herva R, Kiuru M, Nupponen NN, ... Eng C, et al. Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma. American Journal of Human Genetics. 74: 153-9. PMID 14685938 DOI: 10.1086/381054  1
2003 Astuti D, Hart-Holden N, Latif F, Lalloo F, Black GC, Lim C, Moran A, Grossman AB, Hodgson SV, Freemont A, Ramsden R, Eng C, Evans DG, Maher ER. Genetic analysis of mitochondrial complex II subunits SDHD, SDHB and SDHC in paraganglioma and phaeochromocytoma susceptibility. Clinical Endocrinology. 59: 728-33. PMID 14974914 DOI: 10.1046/J.1365-2265.2003.01914.X  1
2003 McWhinney SR, Boru G, Binkley PK, Peczkowska M, Januszewicz AA, Neumann HP, Eng C. Intronic single nucleotide polymorphisms in the RET protooncogene are associated with a subset of apparently sporadic pheochromocytoma and may modulate age of onset. The Journal of Clinical Endocrinology and Metabolism. 88: 4911-6. PMID 14557473 DOI: 10.1210/Jc.2003-030245  1
2003 Waite KA, Eng C. From developmental disorder to heritable cancer: It's all in the BMP/TGF-β family Nature Reviews Genetics. 4: 763-773. PMID 14526373 DOI: 10.1038/Nrg1178  1
2003 Eng C. Constipation, polyps, or cancer? Let PTEN predict your future American Journal of Medical Genetics. 122: 315-322. PMID 14518069 DOI: 10.1002/Ajmg.A.20477  1
2003 Drovdlic CM, Goddard KA, Chak A, Brock W, Chessler L, King JF, Richter J, Falk GW, Johnston DK, Fisher JL, Grady WM, Lemeshow S, Eng C. Demographic and phenotypic features of 70 families segregating Barrett's oesophagus and oesophageal adenocarcinoma. Journal of Medical Genetics. 40: 651-6. PMID 12960209 DOI: 10.1136/Jmg.40.9.651  1
2003 Eng C. PTEN: One gene, Many syndromes Human Mutation. 22: 183-198. PMID 12938083 DOI: 10.1002/Humu.10257  1
2003 Zhou XP, Waite KA, Pilarski R, Hampel H, Fernandez MJ, Bos C, Dasouki M, Feldman GL, Greenberg LA, Ivanovich J, Matloff E, Patterson A, Pierpont ME, Russo D, Nassif NT, Eng C, et al. Germline PTEN promoter mutations and deletions in Cowden/Bannayan-Riley-Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathway. American Journal of Human Genetics. 73: 404-11. PMID 12844284 DOI: 10.1086/377109  1
2003 Gupta RA, Sarraf P, Mueller E, Brockman JA, Prusakiewicz JJ, Eng C, Willson TM, DuBois RN. Peroxisome proliferator-activated receptor gamma-mediated differentiation: a mutation in colon cancer cells reveals divergent and cell type-specific mechanisms. The Journal of Biological Chemistry. 278: 22669-77. PMID 12591919 DOI: 10.1074/Jbc.M300637200  1
2003 Borrego S, Wright FA, Fernández RM, Williams N, López-Alonso M, Davuluri R, Antiñolo G, Eng C. A founding locus within the RET proto-oncogene may account for a large proportion of apparently sporadic Hirschsprung disease and a subset of cases of sporadic medullary thyroid carcinoma. American Journal of Human Genetics. 72: 88-100. PMID 12474140 DOI: 10.1086/345466  1
2002 Girnun GD, Smith WM, Drori S, Sarraf P, Mueller E, Eng C, Nambiar P, Rosenberg DW, Bronson RT, Edelmann W, Kucherlapati R, Gonzalez FJ, Spiegelman BM. APC-dependent suppression of colon carcinogenesis by PPARgamma. Proceedings of the National Academy of Sciences of the United States of America. 99: 13771-6. PMID 12370429 DOI: 10.1073/Pnas.162480299  1
2002 Maher ER, Eng C. The pressure rises: Update on the genetics of phaeochromocytoma Human Molecular Genetics. 11: 2347-2354. PMID 12351569 DOI: 10.1093/Hmg/11.20.2347  1
2002 Eng C. Role of PTEN, a lipid phosphatase upstream effector of protein kinase B, in epithelial thyroid carcinogenesis Annals of the New York Academy of Sciences. 968: 213-221. PMID 12119278 DOI: 10.1111/J.1749-6632.2002.Tb04337.X  1
2002 Weng LP, Brown JL, Baker KM, Ostrowski MC, Eng C. PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway. Human Molecular Genetics. 11: 1687-96. PMID 12095911 DOI: 10.1093/Hmg/11.15.1687  1
2002 Neumann HP, Bausch B, McWhinney SR, Bender BU, Gimm O, Franke G, Schipper J, Klisch J, Altehoefer C, Zerres K, Januszewicz A, Eng C, Smith WM, Munk R, Manz T, ... Eng C, et al. Germ-line mutations in nonsyndromic pheochromocytoma. The New England Journal of Medicine. 346: 1459-66. PMID 12000816 DOI: 10.1056/Nejmoa020152  1
2002 Humar B, Toro T, Graziano F, Müller H, Dobbie Z, Kwang-Yang H, Eng C, Hampel H, Gilbert D, Winship I, Parry S, Ward R, Findlay M, Christian A, Tucker M, et al. Novel germline CDH1 mutations in hereditary diffuse gastric cancer families. Human Mutation. 19: 518-25. PMID 11968084 DOI: 10.1002/Humu.10067  1
2002 Whiteman DC, Zhou XP, Cummings MC, Pavey S, Hayward NK, Eng C. Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma International Journal of Cancer. 99: 63-67. PMID 11948493 DOI: 10.1002/Ijc.10294  1
2002 Waite KA, Eng C. Protean PTEN: Form and function American Journal of Human Genetics. 70: 829-844. PMID 11875759 DOI: 10.1086/340026  1
2002 Stratakis CA, Miller WR, Severin E, Chin KV, Bertherat J, Amieux PS, Eng C, Kammer GM, Dumont JE, Tortora G, Beaven MA, Puck TT, Jan de Beur SM, Weistein LS, Cho-Chung YS. Protein-kinase a and human disease: The core of cAMP-dependent signaling in health and disease Hormone and Metabolic Research. 34: 169-175. DOI: 10.1055/S-2002-26710  1
2001 Huang Y, Prasad M, Lemon WJ, Hampel H, Wright FA, Kornacker K, LiVolsi V, Frankel W, Kloos RT, Eng C, Pellegata NS, de la Chapelle A. Gene expression in papillary thyroid carcinoma reveals highly consistent profiles. Proceedings of the National Academy of Sciences of the United States of America. 98: 15044-9. PMID 11752453 DOI: 10.1073/Pnas.251547398  1
2001 Eng C, Brody LC, Wagner TM, Devilee P, Vijg J, Szabo C, Tavtigian SV, Nathanson KL, Ostrander E, Frank TS. Interpreting epidemiological research: blinded comparison of methods used to estimate the prevalence of inherited mutations in BRCA1. Journal of Medical Genetics. 38: 824-33. PMID 11748305 DOI: 10.1136/Jmg.38.12.824  1
2001 Kurose K, Hoshaw-Woodard S, Adeyinka A, Lemeshow S, Watson PH, Eng C. Genetic model of multi-step breast carcinogenesis involving the epithelium and stroma: Clues to tumour-microenvironment interactions Human Molecular Genetics. 10: 1907-1913. PMID 11555627 DOI: 10.1093/Hmg/10.18.1907  1
2001 Marsh DJ, Theodosopoulos G, Howell V, Richardson AL, Benn DE, Proos AL, Eng C, Robinson BG. Rapid mutation scanning of genes associated with familial cancer syndromes using denaturing high-performance liquid chromatography Neoplasia. 3: 236-244. PMID 11494117 DOI: 10.1038/Sj.Neo.7900154  1
2001 Dahia PLM, Eng C. Hereditary endocrine neoplasias: Fundamental insights and the practice of clinical cancer genetics Frontiers of Hormone Research. 28: 8-19. PMID 11443854 DOI: 10.1159/000061049  1
2001 Dahia PL, Eng C. Genetic disorders of endocrine neoplasia. Introduction. Frontiers of Hormone Research. 28: 1-7. PMID 11443848 DOI: 10.1159/000061048  1
2001 Smiraglia DJ, Rush LJ, Frühwald MC, Dai Z, Held WA, Costello JF, Lang JC, Eng C, Li B, Wright FA, Caligiuri MA, Plass C. Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies Human Molecular Genetics. 10: 1413-1419. PMID 11440994 DOI: 10.1093/Hmg/10.13.1413  1
2001 Eng C. To be or not to BMP Nature Genetics. 28: 105-107. PMID 11381248 DOI: 10.1038/88802  1
2001 Parisi MA, Dinulos MB, Leppig KA, Sybert VP, Eng C, Hudgins L. The spectrum and evolution of phenotypic findings in PTEN mutation positive cases of Bannayan-Riley-Ruvalcaba syndrome. Journal of Medical Genetics. 38: 52-8. PMID 11332402 DOI: 10.1136/JMG.38.1.52  1
2001 Gimm O, Chi H, Dahia PLM, Perren A, Hinze R, Komminoth P, Dralle H, Reynolds PR, Eng C. Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity to PTEN on 10q23.3, in follicular thyroid carcinomas Journal of Clinical Endocrinology and Metabolism. 86: 1801-1805. PMID 11297621 DOI: 10.1210/Jcem.86.4.7419  1
2001 Fackenthal JD, Marsh DJ, Richardson AL, Cummings SA, Eng C, Robinson BG, Olopade OI. Male breast cancer in Cowden syndrome patients with germline PTEN mutations. Journal of Medical Genetics. 38: 159-64. PMID 11238682 DOI: 10.1136/Jmg.38.3.159  1
2000 Eng C. Multiple Endocrine Neoplasia Type 2 and the Practice of Molecular Medicine Reviews in Endocrine and Metabolic Disorders. 1: 283-290. PMID 11706742 DOI: 10.1023/A:1026514301172  1
2000 Dahia PM, Gimm O, Chi H, Marsh DJ, Reynolds PR, Eng C. Absence of germline mutations in MINPP1, a phosphatase encoding gene centromeric of PTEN, in patients with Cowden and Bannayan-Riley-Ruvalcaba syndrome without germline PTEN mutations [7] Journal of Medical Genetics. 37: 715-717. PMID 11182934 DOI: 10.1136/Jmg.37.9.715  1
2000 Eng C. Will the real Cowden syndrome please stand up: Revised diagnostic criteria Journal of Medical Genetics. 37: 828-830. PMID 11073535 DOI: 10.1136/Jmg.37.11.828  1
2000 Mueller E, Smith M, Sarraf P, Kroll T, Aiyer A, Kaufman DS, Oh W, Demetri G, Figg WD, Zhou XP, Eng C, Spiegelman BM, Kantoff PW. Effects of ligand activation of peroxisome proliferator-activated receptor γ in human prostate cancer Proceedings of the National Academy of Sciences of the United States of America. 97: 10990-10995. PMID 10984506 DOI: 10.1073/Pnas.180329197  1
2000 Syngal S, Fox EA, Eng C, Kolodner RD, Garber JE. Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1. Journal of Medical Genetics. 37: 641-5. PMID 10978352 DOI: 10.1136/Jmg.37.9.641  1
2000 Grady WM, Willis J, Guilford PJ, Dunbier AK, Toro TT, Lynch H, Wiesner G, Ferguson K, Eng C, Park JG, Kim SJ, Markowitz S. Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer Nature Genetics. 26: 16-17. PMID 10973239 DOI: 10.1038/79120  1
2000 Borrego S, Ruiz A, Saez ME, Gimm O, Gao X, López-Alonso M, Hernández A, Wright FA, Antiñolo G, Eng C. RET genotypes comprising specific haplotypes of polymorphic variants predispose to isolated Hirschsprung disease. Journal of Medical Genetics. 37: 572-8. PMID 10922382 DOI: 10.1136/Jmg.37.8.572  1
2000 Zhou XP, Smith WM, Gimm O, Mueller E, Gao X, Sarraf P, Prior TW, Plass C, von Deimling A, Black PM, Yates AJ, Eng C. Over-representation of PPARgamma sequence variants in sporadic cases of glioblastoma multiforme: preliminary evidence for common low penetrance modifiers for brain tumour risk in the general population. Journal of Medical Genetics. 37: 410-4. PMID 10851250 DOI: 10.1136/Jmg.37.6.410  1
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