Paul A. Goepfert - Publications

Affiliations: 
University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Microbiology Biology

159 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Walsh SR, Gay CL, Karuna ST, Hyrien O, Skalland T, Mayer KH, Sobieszczyk ME, Baden LR, Goepfert PA, Del Rio C, Pantaleo G, Andrew P, Karg C, He Z, Lu H, et al. A Randomised Clinical Trial of the Safety and Pharmacokinetics of VRC07-523LS Administered via Different Routes and Doses (HVTN 127/HPTN 087). Medrxiv : the Preprint Server For Health Sciences. PMID 38260276 DOI: 10.1101/2024.01.10.23299799  0.391
2023 Reeves DB, Mayer BT, deCamp AC, Huang Y, Zhang B, Carpp LN, Magaret CA, Juraska M, Gilbert PB, Montefiori DC, Bar KJ, Cardozo-Ojeda EF, Schiffer JT, Rossenkhan R, Edlefsen P, ... ... Goepfert PA, et al. High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials. Nature Communications. 14: 8299. PMID 38097552 DOI: 10.1038/s41467-023-43384-y  0.363
2023 Jost S, Lucar O, Lee E, Yoder T, Kroll K, Sugawara S, Smith S, Jones R, Tweet G, Werner A, Tomezsko PJ, Dugan HL, Ghofrani J, Rascle P, Altfeld M, ... ... Goepfert P, et al. Antigen-specific memory NK cell responses against HIV and influenza use the NKG2/HLA-E axis. Science Immunology. 8: eadi3974. PMID 38064568 DOI: 10.1126/sciimmunol.adi3974  0.391
2023 Sugawara S, Hueber B, Woolley G, Terry K, Kroll K, Manickam C, Ram DR, Ndhlovu LC, Goepfert P, Jost S, Reeves RK. Multiplex interrogation of the NK cell signalome reveals global downregulation of CD16 signaling during lentivirus infection through an IL-18/ADAM17-dependent mechanism. Plos Pathogens. 19: e1011629. PMID 37669308 DOI: 10.1371/journal.ppat.1011629  0.416
2023 Cohen KW, Fiore-Gartland A, Walsh SR, Yusim K, Frahm N, Elizaga ML, Maenza J, Scott H, Mayer KH, Goepfert PA, Edupuganti S, Pantaleo G, Hutter J, Morris DE, De Rosa SC, et al. Trivalent mosaic or consensus HIV immunogens prime humoral and broader cellular immune responses in adults. The Journal of Clinical Investigation. 133. PMID 36787249 DOI: 10.1172/JCI163338  0.494
2022 Stieh DJ, Barouch DH, Comeaux C, Sarnecki M, Stephenson KE, Walsh SR, Sawant S, Heptinstall J, Tomaras GD, Kublin JG, McElrath MJ, Cohen KW, De Rosa SC, Alter G, Ferrari G, ... ... Goepfert PA, et al. Safety and Immunogenicity of Ad26-vectored HIV Vaccine with Mosaic Immunogens and a Novel Mosaic Envelope Protein in HIV-uninfected Adults: A Phase 1/2a Study. The Journal of Infectious Diseases. PMID 36348617 DOI: 10.1093/infdis/jiac445  0.429
2022 Huang Y, Zhang Y, Seaton KE, De Rosa S, Heptinstall J, Carpp LN, Randhawa AK, McKinnon LR, McLaren P, Viegas E, Gray GE, Churchyard G, Buchbinder SP, Edupuganti S, Bekker LG, ... ... Goepfert PA, et al. Baseline host determinants of robust human HIV-1 vaccine-induced immune responses: A meta-analysis of 26 vaccine regimens. Ebiomedicine. 84: 104271. PMID 36179551 DOI: 10.1016/j.ebiom.2022.104271  0.375
2022 Files JK, Sterrett S, Henostroza S, Fucile C, Maroney K, Fram T, Mallal S, Kalams S, Carlson J, Rosenberg A, Erdmann N, Bansal A, Goepfert PA. HLA-II-Associated HIV-1 Adaptation Decreases CD4 T-Cell Responses in HIV-1 Vaccine Recipients. Journal of Virology. e0119122. PMID 36000845 DOI: 10.1128/jvi.01191-22  0.535
2021 Currenti J, Law BMP, Qin K, John M, Pilkinton MA, Bansal A, Leary S, Ram R, Chopra A, Gangula R, Yue L, Warren C, Barnett L, Alves E, McDonnell WJ, ... ... Goepfert P, et al. Cross-Reactivity to Mutated Viral Immune Targets Can Influence CD8 T Cell Functionality: An Alternative Viral Adaptation Strategy. Frontiers in Immunology. 12: 746986. PMID 34764960 DOI: 10.3389/fimmu.2021.746986  0.49
2021 Boppana S, Qin K, Files JK, Russell RM, Stoltz R, Bibollet-Ruche F, Bansal A, Erdmann N, Hahn BH, Goepfert PA. SARS-CoV-2-specific circulating T follicular helper cells correlate with neutralizing antibodies and increase during early convalescence. Plos Pathogens. 17: e1009761. PMID 34270631 DOI: 10.1371/journal.ppat.1009761  0.347
2021 Huang Y, Seaton KE, Casapia M, Polakowski L, De Rosa SC, Cohen K, Yu C, Elizaga M, Paez C, Miner MD, Kelley CF, Maenza J, Keefer M, Lama JR, Sobieszczyk M, ... ... Goepfert P, et al. AIDSVAX protein boost improves breadth and magnitude of vaccine-induced HIV-1 envelope-specific responses after a 7-year rest period. Vaccine. PMID 34229888 DOI: 10.1016/j.vaccine.2021.06.066  0.368
2021 Bansal A, Gehre MN, Qin K, Sterrett S, Ali A, Dang Y, Abraham S, Costanzo MC, Venegas LA, Tang J, Manjunath N, Brockman MA, Yang OO, Kan-Mitchell J, Goepfert PA. HLA-E-restricted HIV-1-specific CD8+ T cell responses in natural infection. The Journal of Clinical Investigation. PMID 34228645 DOI: 10.1172/JCI148979  0.541
2021 Qin K, Boppana S, Carlson JM, Fiore-Gartland A, Files J, Zeng J, Edberg J, Mailliard RB, Ochsenbauer C, Bansal A, Goepfert P. Elevated HIV infection of CD4 T cells in MRKAd5 vaccine recipients due to CD8 T cells targeting of adapted epitopes. Journal of Virology. JVI0016021. PMID 34076482 DOI: 10.1128/JVI.00160-21  0.557
2021 Seaton KE, Deal A, Han X, Li SS, Clayton A, Heptinstall J, Duerr A, Allen MA, Shen X, Sawant S, Yates NL, Spearman P, Churchyard G, Goepfert PA, Maenza J, et al. Meta-analysis of HIV-1 vaccine elicited mucosal antibodies in humans. Npj Vaccines. 6: 56. PMID 33859204 DOI: 10.1038/s41541-021-00305-8  0.418
2020 Boppana S, Qin K, Files JK, Russell RM, Stoltz R, Bibollet-Ruche F, Bansal A, Erdmann N, Hahn BH, Goepfert PA. SARS-CoV-2-specific peripheral T follicular helper cells correlate with neutralizing antibodies and increase during convalescence. Medrxiv : the Preprint Server For Health Sciences. PMID 33052359 DOI: 10.1101/2020.10.07.20208488  0.352
2020 Baden LR, Stieh DJ, Sarnecki M, Walsh SR, Tomaras GD, Kublin JG, McElrath MJ, Alter G, Ferrari G, Montefiori D, Mann P, Nijs S, Callewaert K, Goepfert P, Edupuganti S, et al. Safety and immunogenicity of two heterologous HIV vaccine regimens in healthy, HIV-uninfected adults (TRAVERSE): a randomised, parallel-group, placebo-controlled, double-blind, phase 1/2a study. The Lancet. Hiv. 7: e688-e698. PMID 33010242 DOI: 10.1016/S2352-3018(20)30229-0  0.379
2020 Palli R, Seaton KE, Piepenbrink MS, Hural J, Goepfert PA, Laher F, Buchbinder SP, Churchyard G, Gray GE, Robinson HL, Huang Y, Janes H, Kobie JJ, Keefer MC, Tomaras GD, et al. Impact of vaccine type on HIV-1 vaccine elicited antibody durability and B cell gene signature. Scientific Reports. 10: 13031. PMID 32747654 DOI: 10.1038/S41598-020-69007-W  0.464
2020 Sekine T, Perez-Potti A, Nguyen S, Gorin JB, Wu VH, Gostick E, Llewellyn-Lacey S, Hammer Q, Falck-Jones S, Vangeti S, Yu M, Smed-Sörensen A, Gaballa A, Uhlin M, Sandberg JK, ... ... Goepfert PA, et al. TOX is expressed by exhausted and polyfunctional human effector memory CD8 T cells. Science Immunology. 5. PMID 32620560 DOI: 10.1126/Sciimmunol.Aba7918  0.498
2020 El-Badry E, Macharia G, Claiborne D, Brooks K, Dilernia DA, Goepfert P, Kilembe W, Allen S, Gilmour J, Hunter E. Better viral control despite higher CD4 T cell activation during acute HIV-1 infection in Zambian women is linked to the sex hormone estradiol. Journal of Virology. PMID 32461316 DOI: 10.1128/Jvi.00758-20  0.537
2020 Sterrett S, Peng BJ, Burton RL, LaFon DC, Westfall AO, Singh S, Pride M, Anderson AS, Ippolito GC, Schroeder HW, Nahm MH, Krishna Prasad A, Goepfert P, Bansal A. Peripheral CD4 T follicular cells induced by a conjugated pneumococcal vaccine correlate with enhanced opsonophagocytic antibody responses in younger individuals. Vaccine. PMID 31911030 DOI: 10.1016/J.Vaccine.2019.12.023  0.422
2019 Kallas EG, Grunenberg NA, Yu C, Manso B, Pantaleo G, Casapia M, Baden LR, Valencia J, Sobieszczyk M, Van Tieu H, Allen M, Hural J, Graham BS, Kublin J, Gilbert PB, ... ... Goepfert PA, et al. Antigenic competition in CD4 T cell responses in a randomized, multicenter, double-blind clinical HIV vaccine trial. Science Translational Medicine. 11. PMID 31748227 DOI: 10.1126/Scitranslmed.Aaw1673  0.574
2019 Boppana S, Fiore-Gartland A, Bansal A, Goepfert P. Cross-reactive CD8 T-cell responses elicited by Ad5-based HIV-1 vaccines contributed to early viral evolution in vaccine recipients who became infected. Journal of Virology. PMID 31645444 DOI: 10.1128/Jvi.01632-19  0.581
2019 Qin K, Boppana S, Du VY, Carlson JM, Yue L, Dilernia DA, Hunter E, Mailliard RB, Mallal SA, Bansal A, Goepfert PA. CD8 T cells targeting adapted epitopes in chronic HIV infection promote dendritic cell maturation and CD4 T cell trans-infection. Plos Pathogens. 15: e1007970. PMID 31398241 DOI: 10.1371/Journal.Ppat.1007970  0.547
2019 Boppana S, Sterrett S, Files J, Qin K, Fiore-Gartland A, Cohen KW, De Rosa SC, Bansal A, Goepfert PA. HLA-I associated adaptation dampens the CD8 T-cell response in HIV Ad5-vectored vaccine recipients. The Journal of Infectious Diseases. PMID 31301135 DOI: 10.1093/Infdis/Jiz368  0.54
2019 Edupuganti S, Mgodi NM, Karuna S, Andrew P, Kochar N, Marshall K, Decamp A, Takuva S, Anderson M, De La Grecca R, Gomez Lorenzo M, Burns D, Goepfert P, McElrath J, Casapia M, et al. 1272. Feasibility and Successful Enrollment in Proof-of-Concept Trials to Assess Safety and Efficacy of a Broadly Neutralizing Monoclonal Antibody, VRC01, to Prevent HIV-1 Acquisitionin in Uninfected Individuals Open Forum Infectious Diseases. 6: S457-S458. DOI: 10.1093/Ofid/Ofz360.1135  0.395
2018 Boppana S, Goepfert P. Understanding the CD8 T-cell response in natural HIV control. F1000research. 7. PMID 30026916 DOI: 10.12688/F1000Research.15029.1  0.626
2018 Peng BJ, Carlson JM, Liu MKP, Gao F, Goonetilleke N, McMichael AJ, Borrow P, Gilmour J, Heath SL, Hunter E, Bansal A, Goepfert PA. Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection. Journal of Virology. PMID 30021907 DOI: 10.1128/Jvi.00711-18  0.635
2018 Manickam C, Nwanze C, Ram DR, Shah SV, Smith S, Jones R, Hueber B, Kroll K, Varner V, Goepfert P, Jost S, Reeves RK. Progressive lentivirus infection induces natural killer cell receptor-expressing B cells in the gastrointestinal tract. Aids (London, England). PMID 29734222 DOI: 10.1097/Qad.0000000000001855  0.443
2018 Autissier E, Li H, Goepfert P, Reeves RK. Apoptotic membrane microparticles quantified by fluorescent bead-based assay are elevated in HIV and SIV infections. Aids Research and Human Retroviruses. PMID 29486582 DOI: 10.1089/Aid.2018.0011  0.409
2017 Wiener HW, Shrestha S, Lu H, Karita E, Kilembe W, Allen S, Hunter E, Goepfert PA, Tang J. Immunogenetic Factors in Early Immune Control of Human Immunodeficiency Virus Type 1 (HIV-1) Infection: Evaluation of HLA Class I Amino Acid Variants in Two African Populations. Human Immunology. PMID 29289742 DOI: 10.1016/J.Humimm.2017.12.005  0.519
2017 Seu L, Tidwell C, Timares L, Duverger A, Wagner FH, Goepfert PA, Westfall AO, Sabbaj S, Kutsch O. CD151 Expression Is Associated with a Hyperproliferative T Cell Phenotype. Journal of Immunology (Baltimore, Md. : 1950). PMID 28954890 DOI: 10.4049/Jimmunol.1700648  0.435
2017 Buchbinder SP, Grunenberg NA, Sanchez BJ, Seaton KE, Ferrari G, Moody MA, Frahm N, Montefiori DC, Hay CM, Goepfert PA, Baden LR, Robinson HL, Yu X, Gilbert PB, McElrath MJ, et al. Immunogenicity of a novel Clade B HIV-1 vaccine combination: Results of phase 1 randomized placebo controlled trial of an HIV-1 GM-CSF-expressing DNA prime with a modified vaccinia Ankara vaccine boost in healthy HIV-1 uninfected adults. Plos One. 12: e0179597. PMID 28727817 DOI: 10.1371/Journal.Pone.0179597  0.503
2017 Seu L, Mobley JA, Goepfert PA. CD4+ T cells from HIV-1 patients with impaired Th1 effector responses to Mycobacterium tuberculosis exhibit diminished histone and nucleoprotein signatures. Clinical Immunology (Orlando, Fla.). PMID 28552470 DOI: 10.1016/J.Clim.2017.05.018  0.618
2017 Hel Z, Xu J, Denning WL, Helton ES, Huijbregts RP, Heath SL, Overton ET, Christmann BS, Elson CO, Goepfert PA, Mestecky J. Dysregulation of Systemic and Mucosal Humoral Responses to Microbial and Food Antigens as a Factor Contributing to Microbial Translocation and Chronic Inflammation in HIV-1 Infection. Plos Pathogens. 13: e1006087. PMID 28125732 DOI: 10.1371/Journal.Ppat.1006087  0.574
2017 Boppana S, Sterett S, Qin K, Bansal A, Goepfert P. HIV-specific CD8 T Cell Cross-reactivity Following Ad5-based Vaccination Is Shaped by Vaccine Regimen and Prior Ad5 Exposure Open Forum Infectious Diseases. 4: S222-S222. DOI: 10.1093/Ofid/Ofx163.457  0.469
2016 Moylan DC, Goepfert PA, Kempf MC, Saag MS, Richter HE, Mestecky J, Sabbaj S. Diminished CD103 (αEβ7) Expression on Resident T Cells from the Female Genital Tract of HIV-Positive Women. Pathogens & Immunity. 1: 371-387. PMID 28164171 DOI: 10.20411/pai.v1i2.166  0.417
2016 Salazar-Gonzalez JF, Salazar MG, Tully DC, Ogilvie CB, Learn GH, Allen TM, Heath SL, Goepfert P, Bar KJ. Use of Dried Blood Spots to Elucidate Full-Length Transmitted/Founder HIV-1 Genomes. Pathogens & Immunity. 1: 129-153. PMID 27819061 DOI: 10.20411/pai.v1i1.116  0.359
2016 Prentice HA, Lu H, Price MA, Kamali A, Karita E, Lakhi S, Sanders EJ, Anzala O, Allen S, Goepfert PA, Hunter E, Gilmour J, Tang J. Dynamics and Correlates of CD8 T-cell Counts in Africans with Primary Human Immunodeficient Virus Type I (HIV-1) Infection. Journal of Virology. PMID 27630231 DOI: 10.1128/Jvi.01467-16  0.559
2016 Mónaco DC, Dilernia DA, Fiore-Gartland A, Yu T, Prince JL, Dennis KK, Qin K, Schaefer M, Claiborne DT, Kilembe W, Tang J, Price MA, Farmer P, Gilmour J, Bansal A, ... ... Goepfert P, et al. Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progression. The Journal of Experimental Medicine. PMID 27551154 DOI: 10.1084/Jem.20151984  0.529
2016 Carlson JM, Du VY, Pfeifer N, Bansal A, Tan VY, Power K, Brumme CJ, Kreimer A, DeZiel CE, Fusi N, Schaefer M, Brockman MA, Gilmour J, Price MA, Kilembe W, ... ... Goepfert PA, et al. Impact of pre-adapted HIV transmission. Nature Medicine. PMID 27183217 DOI: 10.1038/Nm.4100  0.627
2016 Du VY, Bansal A, Carlson J, Salazar-Gonzalez JF, Salazar MG, Ladell K, Gras S, Josephs TM, Heath SL, Price DA, Rossjohn J, Hunter E, Goepfert PA. HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 26983786 DOI: 10.4049/Jimmunol.1502411  0.634
2016 Chan CN, Trinité B, Lee CS, Mahajan S, Anand A, Wodarz D, Sabbaj S, Bansal A, Goepfert PA, Levy DN. HIV-1 latency and virus production from unintegrated genomes following direct infection of resting CD4 T cells. Retrovirology. 13: 1. PMID 26728316 DOI: 10.1186/S12977-015-0234-9  0.624
2015 Sabbaj S, Scanlon N, Du VY, Wang Y, Tang J, Hunter E, Goepfert PA. Enhanced allogeneic cellular responses to mismatched HLA-B antigens results in more efficient killing of HIV infected cells. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 26588705 DOI: 10.1097/Qai.0000000000000901  0.559
2015 Fuchs JD, Bart PA, Frahm N, Morgan C, Gilbert PB, Kochar N, DeRosa SC, Tomaras GD, Wagner TM, Baden LR, Koblin BA, Rouphael NG, Kalams SA, Keefer MC, Goepfert PA, et al. Safety and Immunogenicity of a Recombinant Adenovirus Serotype 35-Vectored HIV-1 Vaccine in Adenovirus Serotype 5 Seronegative and Seropositive Individuals. Journal of Aids & Clinical Research. 6. PMID 26587311 DOI: 10.4172/2155-6113.1000461  0.479
2015 Bansal A, Sterrett S, Erdmann N, Westfall AO, Dionne-Odom J, Overton ET, Goepfert PA. Normal T-cell activation in elite controllers with preserved CD4+ T-cell counts. Aids (London, England). 29: 2245-54. PMID 26544698 DOI: 10.1097/Qad.0000000000000860  0.538
2015 Walsh SR, Moodie Z, Fiore-Gartland AJ, Morgan C, Wilck MB, Hammer SM, Buchbinder SP, Kalams SA, Goepfert PA, Mulligan MJ, Keefer MC, Baden LR, Swann EM, Grant S, Ahmed H, et al. Vaccination with heterologous HIV envelope sequences and heterologous adenovirus vectors increases T cell responses to conserved regions (HVTN 083). The Journal of Infectious Diseases. PMID 26475930 DOI: 10.1093/Infdis/Jiv496  0.535
2015 Overton ET, Stapleton J, Frank I, Hassler S, Goepfert PA, Barker D, Wagner E, von Krempelhuber A, Virgin G, Meyer TP, Müller J, Bädeker N, Grünert R, Young P, Rösch S, et al. Safety and Immunogenicity of Modified Vaccinia Ankara-Bavarian Nordic Smallpox Vaccine in Vaccinia-Naive and Experienced Human Immunodeficiency Virus-Infected Individuals: An Open-Label, Controlled Clinical Phase II Trial. Open Forum Infectious Diseases. 2: ofv040. PMID 26380340 DOI: 10.1093/Ofid/Ofv040  0.533
2015 Bansal A, Mann T, Sterrett S, Peng BJ, Bet A, Carlson JM, Goepfert PA. Enhanced Recognition of HIV-1 Cryptic Epitopes Restricted by HLA Class I Alleles Associated With a Favorable Clinical Outcome. Journal of Acquired Immune Deficiency Syndromes (1999). 70: 1-8. PMID 26322665 DOI: 10.1097/Qai.0000000000000700  0.469
2015 Erdmann N, Du VY, Carlson J, Schaefer M, Jureka A, Sterrett S, Yue L, Dilernia D, Lakhi S, Tang J, Sidney J, Gilmour J, Allen S, Hunter E, Heath S, ... ... Goepfert PA, et al. HLA Class-II Associated HIV Polymorphisms Predict Escape from CD4+ T Cell Responses. Plos Pathogens. 11: e1005111. PMID 26302050 DOI: 10.1371/Journal.Ppat.1005111  0.651
2015 Seu L, Sabbaj S, Duverger A, Wagner F, Anderson JC, Davies E, Wolschendorf F, Willey CD, Saag MS, Goepfert P, Kutsch O. Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection. Journal of Virology. 89: 6656-72. PMID 25878110 DOI: 10.1128/Jvi.00571-15  0.598
2015 Bet A, Maze EA, Bansal A, Sterrett S, Gross A, Graff-Dubois S, Samri A, Guihot A, Katlama C, Theodorou I, Mesnard JM, Moris A, Goepfert PA, Cardinaud S. The HIV-1 antisense protein (ASP) induces CD8 T cell responses during chronic infection. Retrovirology. 12: 15. PMID 25809376 DOI: 10.1186/S12977-015-0135-Y  0.641
2015 Claiborne DT, Prince JL, Scully E, Macharia G, Micci L, Lawson B, Kopycinski J, Deymier MJ, Vanderford TH, Nganou-Makamdop K, Ende Z, Brooks K, Tang J, Yu T, Lakhi S, ... ... Goepfert PA, et al. Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression. Proceedings of the National Academy of Sciences of the United States of America. 112: E1480-9. PMID 25730868 DOI: 10.1073/Pnas.1421607112  0.626
2015 Stoddard MB, Li H, Wang S, Saeed M, Andrus L, Ding W, Jiang X, Learn GH, von Schaewen M, Wen J, Goepfert PA, Hahn BH, Ploss A, Rice CM, Shaw GM. Identification, molecular cloning, and analysis of full-length hepatitis C virus transmitted/founder genotypes 1, 3, and 4. Mbio. 6: e02518. PMID 25714714 DOI: 10.1128/Mbio.02518-14  0.405
2015 Yue L, Pfafferott KJ, Baalwa J, Conrod K, Dong CC, Chui C, Rong R, Claiborne DT, Prince JL, Tang J, Ribeiro RM, Cormier E, Hahn BH, Perelson AS, Shaw GM, ... ... Goepfert P, et al. Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients. Plos Pathogens. 11: e1004565. PMID 25569444 DOI: 10.1371/Journal.Ppat.1004565  0.596
2015 Erdmann N, Du VY, Carlson J, Schaefer M, Jureka A, Sterrett S, Yue L, Dilernia D, Lakhi S, Tang J, Sidney J, Gilmour J, Allen S, Hunter E, Heath S, ... ... Goepfert PA, et al. List of HLA-II associated HIV-1 polymorphisms. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1005111.T001  0.454
2014 Overton ET, Sterrett S, Westfall AO, Kahan SM, Burkholder G, Zajac AJ, Goepfert PA, Bansal A. Effects of atorvastatin and pravastatin on immune activation and T-cell function in antiretroviral therapy-suppressed HIV-1-infected patients. Aids (London, England). 28: 2627-31. PMID 25574964 DOI: 10.1097/Qad.0000000000000475  0.596
2014 Li H, Goepfert P, Reeves RK. Short communication: Plasmacytoid dendritic cells from HIV-1 Elite Controllers maintain a gut-homing phenotype associated with immune activation. Aids Research and Human Retroviruses. 30: 1213-5. PMID 25387330 DOI: 10.1089/aid.2014.0174  0.543
2014 Goepfert P, Bansal A. Human immunodeficiency virus vaccines. Infectious Disease Clinics of North America. 28: 615-31. PMID 25287587 DOI: 10.1016/J.Idc.2014.08.004  0.484
2014 Bharaj P, Chahar HS, Alozie OK, Rodarte L, Bansal A, Goepfert PA, Dwivedi A, Manjunath N, Shankar P. Characterization of programmed death-1 homologue-1 (PD-1H) expression and function in normal and HIV infected individuals. Plos One. 9: e109103. PMID 25279955 DOI: 10.1371/Journal.Pone.0109103  0.48
2014 Frey SE, Peiperl L, McElrath MJ, Kalams S, Goepfert PA, Keefer MC, Baden LR, Lally MA, Mayer K, Blattner WA, Harro CD, Hammer SM, Gorse GJ, Hural J, Tomaras GD, et al. Phase I/II randomized trial of safety and immunogenicity of LIPO-5 alone, ALVAC-HIV (vCP1452) alone, and ALVAC-HIV (vCP1452) prime/LIPO-5 boost in healthy, HIV-1-uninfected adult participants. Clinical and Vaccine Immunology : Cvi. 21: 1589-99. PMID 25253665 DOI: 10.1128/Cvi.00450-14  0.549
2014 Carlson JM, Schaefer M, Monaco DC, Batorsky R, Claiborne DT, Prince J, Deymier MJ, Ende ZS, Klatt NR, DeZiel CE, Lin TH, Peng J, Seese AM, Shapiro R, Frater J, ... ... Goepfert P, et al. HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck. Science (New York, N.Y.). 345: 1254031. PMID 25013080 DOI: 10.1126/Science.1254031  0.494
2014 Williams LD, Amatya N, Bansal A, Sabbaj S, Heath SL, Sereti I, Goepfert PA. Immune activation is associated with CD8 T cell interleukin-21 production in HIV-1-infected individuals. Journal of Virology. 88: 10259-63. PMID 24942568 DOI: 10.1128/Jvi.00764-14  0.697
2014 Merino AM, Dugast AS, Wilson CM, Goepfert PA, Alter G, Kaslow RA, Tang J. KIR2DS4 promotes HIV-1 pathogenesis: new evidence from analyses of immunogenetic data and natural killer cell function. Plos One. 9: e99353. PMID 24901871 DOI: 10.1371/Journal.Pone.0099353  0.589
2014 Bowers NL, Helton ES, Huijbregts RPH, Goepfert PA, Heath SL, Hel Z. Immune Suppression by Neutrophils in HIV-1 Infection: Role of PD-L1/PD-1 Pathway Plos Pathogens. 10. PMID 24626392 DOI: 10.1371/Journal.Ppat.1003993  0.472
2014 Bet A, Sterrett S, Sato A, Bansal A, Goepfert PA. Characterization of T-cell responses to cryptic epitopes in recipients of a noncodon-optimized HIV-1 vaccine. Journal of Acquired Immune Deficiency Syndromes (1999). 65: 142-50. PMID 24442221 DOI: 10.1097/Qai.0B013E3182A9917E  0.554
2014 Goepfert PA, Elizaga ML, Seaton K, Tomaras GD, Montefiori DC, Sato A, Hural J, DeRosa SC, Kalams SA, McElrath MJ, Keefer MC, Baden LR, Lama JR, Sanchez J, Mulligan MJ, et al. Specificity and 6-month durability of immune responses induced by DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles. The Journal of Infectious Diseases. 210: 99-110. PMID 24403557 DOI: 10.1093/Infdis/Jiu003  0.522
2014 Kaslow RA, Erbelding EJ, Goepfert PA. Human immunodeficiency viruses types 1 and 2 Viral Infections of Humans: Epidemiology and Control. 1001-1062. DOI: 10.1007/978-1-4899-7448-8_43  0.485
2013 Merino AM, Sabbaj S, Easlick J, Goepfert P, Kaslow RA, Tang J. Dimorphic HLA-B signal peptides differentially influence HLA-E- and natural killer cell-mediated cytolysis of HIV-1-infected target cells. Clinical and Experimental Immunology. 174: 414-23. PMID 23952339 DOI: 10.1111/Cei.12187  0.509
2013 Murphy MK, Yue L, Pan R, Boliar S, Sethi A, Tian J, Pfafferot K, Karita E, Allen SA, Cormier E, Goepfert PA, Borrow P, Robinson JE, Gnanakaran S, Hunter E, et al. Viral escape from neutralizing antibodies in early subtype A HIV-1 infection drives an increase in autologous neutralization breadth. Plos Pathogens. 9: e1003173. PMID 23468623 DOI: 10.1371/Journal.Ppat.1003173  0.515
2013 Yan J, Sabbaj S, Bansal A, Amatya N, Shacka JJ, Goepfert PA, Heath SL. HIV-specific CD8+ T cells from elite controllers are primed for survival. Journal of Virology. 87: 5170-81. PMID 23449791 DOI: 10.1128/Jvi.02379-12  0.625
2013 Huijbregts RP, Helton ES, Michel KG, Sabbaj S, Richter HE, Goepfert PA, Hel Z. Hormonal contraception and HIV-1 infection: medroxyprogesterone acetate suppresses innate and adaptive immune mechanisms. Endocrinology. 154: 1282-95. PMID 23354099 DOI: 10.1210/En.2012-1850  0.501
2013 Yue L, Prentice HA, Farmer P, Song W, He D, Lakhi S, Goepfert P, Gilmour J, Allen S, Tang J, Kaslow RA, Hunter E. Cumulative impact of host and viral factors on HIV-1 viral-load control during early infection. Journal of Virology. 87: 708-15. PMID 23115285 DOI: 10.1128/Jvi.02118-12  0.44
2013 Borrow P, Stacey A, Fenton-May A, Dibben O, Haygreen E, Emmerich T, Kim N, Marshall E, Lavender K, Cohen M, Goepfert P, Williams I, Wallace D, Shaw G, Hahn B, et al. Innate immune responses in acute HIV-1 infection: protective or pathogenic? Retrovirology. 10. DOI: 10.1186/1742-4690-10-S1-O33  0.497
2012 Wei Q, Moldoveanu Z, Huang WQ, Alexander RC, Goepfert PA, Mestecky J. Comparative Evaluation of HIV-1 Neutralization in External Secretions and Sera of HIV-1-Infected Women. The Open Aids Journal. 6: 293-302. PMID 23346267 DOI: 10.2174/1874613601206010293  0.547
2012 Prince JL, Claiborne DT, Carlson JM, Schaefer M, Yu T, Lahki S, Prentice HA, Yue L, Vishwanathan SA, Kilembe W, Goepfert P, Price MA, Gilmour J, Mulenga J, Farmer P, et al. Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis. Plos Pathogens. 8: e1003041. PMID 23209412 DOI: 10.1371/Journal.Ppat.1003041  0.545
2012 Janes H, Frahm N, DeCamp A, Rolland M, Gabriel E, Wolfson J, Hertz T, Kallas E, Goepfert P, Friedrich DP, Corey L, Mullins JI, McElrath MJ, Gilbert P. MRKAd5 HIV-1 Gag/Pol/Nef vaccine-induced T-cell responses inadequately predict distance of breakthrough HIV-1 sequences to the vaccine or viral load. Plos One. 7: e43396. PMID 22952672 DOI: 10.1371/Journal.Pone.0043396  0.537
2012 Li H, Stoddard MB, Wang S, Blair LM, Giorgi EE, Parrish EH, Learn GH, Hraber P, Goepfert PA, Saag MS, Denny TN, Haynes BF, Hahn BH, Ribeiro RM, Perelson AS, et al. Elucidation of hepatitis C virus transmission and early diversification by single genome sequencing. Plos Pathogens. 8: e1002880. PMID 22927816 DOI: 10.1371/Journal.Ppat.1002880  0.363
2012 Zhang M, Clausell A, Robinson T, Yin J, Chen E, Johnson L, Weiss G, Sabbaj S, Lowe RM, Wagner FH, Goepfert PA, Kutsch O, Cron RQ. Host factor transcriptional regulation contributes to preferential expression of HIV type 1 in IL-4-producing CD4 T cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 2746-57. PMID 22875803 DOI: 10.4049/Jimmunol.1103129  0.575
2012 Prince J, Claiborne D, Heckerman D, Carlson J, Prentice H, Schaefer M, Yue L, Mulenga J, Tang J, Goepfert P, Farmer P, Kaslow R, Allen S, Hunter E. Impact of transmitted CTL escape mutations on replicative capacity and HIV pathogenesis in early infection Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-O57  0.528
2012 Goepfert P, Elizaga M, Montefiori D, Hural J, DeRosa S, Tomaras G, Seaton K, Sato A, Ouedraogo L, Donastorg Y, Cardinali M, Lama J, Baden L, Keefer M, McElrath J, et al. Phase 2a safety and immunogenicity testing of DNA and recombinant modified vaccinia ankara virus vaccines expressing virus-like particles Retrovirology. 9: 1-1. DOI: 10.1186/1742-4690-9-S2-O56  0.314
2012 Andersen-Nissen E, Zak D, Hensley T, Adams D, Hu X, Sato A, Elizaga M, Goepfert P, Robinson H, Aderem A, McElrath M. Vaccination with MVA/HIV induces differential recruitment of monocyte subsets into the circulation and monocyte-specific transcriptional programs Retrovirology. 9: 1-1. DOI: 10.1186/1742-4690-9-S2-O18  0.422
2012 Lee HY, Giorgi EE, Keele BF, Gaschen B, Athreya GS, Salazar-Gonzalez JF, Pham KT, Goepfert PA, Kilby JM, Saag MS, Delwart EL, Busch MP, Hahn BH, Shaw GM, Korber BT, et al. Corrigendum to "Modeling sequence evolution in acute HIV-1 infection" [J. Theor. Biol. 261 (2009) 341-360] Journal of Theoretical Biology. 297: 187. DOI: 10.1016/J.Jtbi.2011.12.010  0.499
2011 Sabbaj S, Hel Z, Richter HE, Mestecky J, Goepfert PA. Menstrual blood as a potential source of endometrial derived CD3+ T cells. Plos One. 6: e28894. PMID 22174921 DOI: 10.1371/Journal.Pone.0028894  0.389
2011 Liao HX, Chen X, Munshaw S, Zhang R, Marshall DJ, Vandergrift N, Whitesides JF, Lu X, Yu JS, Hwang KK, Gao F, Markowitz M, Heath SL, Bar KJ, Goepfert PA, et al. Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated Journal of Experimental Medicine. 208: 2237-2249. PMID 21987658 DOI: 10.1084/Jem.20110363  0.525
2011 Gnanakaran S, Bhattacharya T, Daniels M, Keele BF, Hraber PT, Lapedes AS, Shen T, Gaschen B, Krishnamoorthy M, Li H, Decker JM, Salazar-Gonzalez JF, Wang S, Jiang C, Gao F, ... ... Goepfert PA, et al. Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections. Plos Pathogens. 7: e1002209. PMID 21980282 DOI: 10.1371/Journal.Ppat.1002209  0.462
2011 Koblin BA, Casapia M, Morgan C, Qin L, Wang ZM, Defawe OD, Baden L, Goepfert P, Tomaras GD, Montefiori DC, McElrath MJ, Saavedra L, Lau CY, Graham BS. Safety and immunogenicity of an HIV adenoviral vector boost after DNA plasmid vaccine prime by route of administration: a randomized clinical trial. Plos One. 6: e24517. PMID 21931737 DOI: 10.1371/Journal.Pone.0024517  0.449
2011 Churchyard GJ, Morgan C, Adams E, Hural J, Graham BS, Moodie Z, Grove D, Gray G, Bekker LG, McElrath MJ, Tomaras GD, Goepfert P, Kalams S, Baden LR, Lally M, et al. A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204). Plos One. 6: e21225. PMID 21857901 DOI: 10.1371/Journal.Pone.0021225  0.516
2011 Akinsiku OT, Bansal A, Sabbaj S, Heath SL, Goepfert PA. Interleukin-2 production by polyfunctional HIV-1-specific CD8 T cells is associated with enhanced viral suppression. Journal of Acquired Immune Deficiency Syndromes (1999). 58: 132-40. PMID 21637109 DOI: 10.1097/Qai.0B013E318224D2E9  0.807
2011 Sabbaj S, Pass RF, Goepfert PA, Pichon S. Glycoprotein B vaccine is capable of boosting both antibody and CD4 T-cell responses to cytomegalovirus in chronically infected women. The Journal of Infectious Diseases. 203: 1534-41. PMID 21592981 DOI: 10.1093/Infdis/Jir138  0.442
2011 Goepfert PA, Elizaga ML, Sato A, Qin L, Cardinali M, Hay CM, Hural J, DeRosa SC, DeFawe OD, Tomaras GD, Montefiori DC, Xu Y, Lai L, Kalams SA, Baden LR, et al. Phase 1 safety and immunogenicity testing of DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles. The Journal of Infectious Diseases. 203: 610-9. PMID 21282192 DOI: 10.1093/Infdis/Jiq105  0.408
2011 Keefer MC, Frey SE, Elizaga M, Metch B, De Rosa SC, Barroso PF, Tomaras G, Cardinali M, Goepfert P, Kalichman A, Philippon V, McElrath MJ, Jin X, Ferrari G, Defawe OD, et al. A phase I trial of preventive HIV vaccination with heterologous poxviral-vectors containing matching HIV-1 inserts in healthy HIV-uninfected subjects. Vaccine. 29: 1948-58. PMID 21216311 DOI: 10.1016/J.Vaccine.2010.12.104  0.62
2011 Williams LD, Bansal A, Sabbaj S, Heath SL, Song W, Tang J, Zajac AJ, Goepfert PA. Interleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllers. Journal of Virology. 85: 2316-24. PMID 21159862 DOI: 10.1128/Jvi.01476-10  0.739
2011 Heath SL, Sabbaj S, Bansal A, Kilby JM, Goepfert PA. CD8 T-cell proliferative capacity is compromised in primary HIV-1 infection. Journal of Acquired Immune Deficiency Syndromes (1999). 56: 213-21. PMID 21079516 DOI: 10.1097/Qai.0B013E3181Ff2Aba  0.634
2010 Subramanya S, Armant M, Salkowitz JR, Nyakeriga AM, Haridas V, Hasan M, Bansal A, Goepfert PA, Wynn KK, Ladell K, Price DA, Manjunath N, Kan-Mitchell J, Shankar P. Enhanced Induction of HIV-specific Cytotoxic T Lymphocytes by Dendritic Cell-targeted Delivery of SOCS-1 siRNA. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 2028-2037. PMID 28178453 DOI: 10.1038/mt.2010.148  0.447
2010 Vaine M, Wang S, Liu Q, Arthos J, Montefiori D, Goepfert P, McElrath MJ, Lu S. Profiles of human serum antibody responses elicited by three leading HIV vaccines focusing on the induction of Env-specific antibodies. Plos One. 5: e13916. PMID 21085486 DOI: 10.1371/Journal.Pone.0013916  0.463
2010 Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, ... ... Goepfert PA, et al. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science (New York, N.Y.). 330: 1551-7. PMID 21051598 DOI: 10.1126/Science.1195271  0.445
2010 Subramanya S, Armant M, Salkowitz JR, Nyakeriga AM, Haridas V, Hasan M, Bansal A, Goepfert PA, Wynn KK, Ladell K, Price DA, N M, Kan-Mitchell J, Shankar P. Enhanced induction of HIV-specific cytotoxic T lymphocytes by dendritic cell-targeted delivery of SOCS-1 siRNA. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 2028-37. PMID 20648001 DOI: 10.1038/Mt.2010.148  0.535
2010 Hersperger AR, Pereyra F, Nason M, Demers K, Sheth P, Shin LY, Kovacs CM, Rodriguez B, Sieg SF, Teixeira-Johnson L, Gudonis D, Goepfert PA, Lederman MM, Frank I, Makedonas G, et al. Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control. Plos Pathogens. 6: e1000917. PMID 20523897 DOI: 10.1371/Journal.Ppat.1000917  0.643
2010 Bansal A, Carlson J, Yan J, Akinsiku OT, Schaefer M, Sabbaj S, Bet A, Levy DN, Heath S, Tang J, Kaslow RA, Walker BD, Ndung'u T, Goulder PJ, Heckerman D, ... ... Goepfert PA, et al. CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription. The Journal of Experimental Medicine. 207: 51-9. PMID 20065064 DOI: 10.1084/Jem.20092060  0.81
2010 Nandi A, Lavine CL, Wang P, Lipchina I, Goepfert PA, Shaw GM, Tomaras GD, Montefiori DC, Haynes BF, Easterbrook P, Robinson JE, Sodroski JG, Yang X. Epitopes for broad and potent neutralizing antibody responses during chronic infection with human immunodeficiency virus type 1. Virology. 396: 339-48. PMID 19922969 DOI: 10.1016/J.Virol.2009.10.044  0.524
2010 Akinsiku O, Goepfert P. Polyfunctional CD8+ T Cell Responses Did Not Predict Efficient Suppression of HIV-1 Replication Clinical Immunology. 135: S54. DOI: 10.1016/J.Clim.2010.03.165  0.802
2009 Lee HY, Giorgi EE, Keele BF, Gaschen B, Athreya GS, Salazar-Gonzalez JF, Pham KT, Goepfert PA, Kilby JM, Saag MS, Delwart EL, Busch MP, Hahn BH, Shaw GM, Korber BT, et al. Modeling sequence evolution in acute HIV-1 infection. Journal of Theoretical Biology. 261: 341-60. PMID 19660475 DOI: 10.1016/J.Jtbi.2009.07.038  0.505
2009 Levesque MC, Moody MA, Hwang KK, Marshall DJ, Whitesides JF, Amos JD, Gurley TC, Allgood S, Haynes BB, Vandergrift NA, Plonk S, Parker DC, Cohen MS, Tomaras GD, Goepfert PA, et al. Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection. Plos Medicine. 6: e1000107. PMID 19582166 DOI: 10.1371/Journal.Pmed.1000107  0.589
2009 Crawford H, Lumm W, Leslie A, Schaefer M, Boeras D, Prado JG, Tang J, Farmer P, Ndung'u T, Lakhi S, Gilmour J, Goepfert P, Walker BD, Kaslow R, Mulenga J, et al. Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients. The Journal of Experimental Medicine. 206: 909-21. PMID 19307327 DOI: 10.1084/Jem.20081984  0.519
2009 Harro CD, Robertson MN, Lally MA, O'Neill LD, Edupuganti S, Goepfert PA, Mulligan MJ, Priddy FH, Dubey SA, Kierstead LS, Sun X, Casimiro DR, DiNubile MJ, Shiver JW, Leavitt RY, et al. Safety and immunogenicity of adenovirus-vectored near-consensus HIV type 1 clade B gag vaccines in healthy adults. Aids Research and Human Retroviruses. 25: 103-14. PMID 19108693 DOI: 10.1089/Aid.2008.0212  0.427
2009 Heath SL, Jiyu J, Bansal A, Sabbaj S, Shacka JJ, Goepfert PA. P16-25. HIV specific CTL from elite controllers have a unique survival advantage Retrovirology. 6: P254. DOI: 10.1186/1742-4690-6-S3-P254  0.473
2009 Bansal A, Carlson J, Matthews P, Akinsiku O, Yan J, Sabbaj S, Heath S, Goulder P, Heckerman D, Goepfert P. P16-04. Cryptic CTL epitopes derived from antisense transcription are frequently recognized in HIV-1 infection Retrovirology. 6: P233. DOI: 10.1186/1742-4690-6-S3-P233  0.8
2009 Hersperger AR, Pereyra F, Demers K, Sheth P, Shin LY, Rodriguez B, Sieg SF, Teixeira-Johnson L, Goepfert PA, Lederman MM, Kaul R, Makedonas G, Walker BD, Betts MR. S03-06 OA. Rapid perforin upregulation by CD8 T cells in elite controllers as a correlate of immune-mediated control of HIV replication Retrovirology. 6: O45. DOI: 10.1186/1742-4690-6-S3-O45  0.588
2009 Munshaw S, Liao H, Dixon A, Chen X, Nagel A, Derosa K, Parks R, Amos J, Whitesides J, Marshalls D, Yang Y, Gao F, Tomaras G, Moody M, Kelsoe G, ... ... Goepfert P, et al. S021-04 OA. A large-scale analysis of immunoglobulin sequences derived from plasmablasts/plasma cells in acute HIV-1 infection subjects Retrovirology. 6: 1-1. DOI: 10.1186/1742-4690-6-S3-O4  0.434
2008 Liu W, Worobey M, Li Y, Keele BF, Bibollet-Ruche F, Guo Y, Goepfert PA, Santiago ML, Ndjango JB, Neel C, Clifford SL, Sanz C, Kamenya S, Wilson ML, Pusey AE, et al. Molecular ecology and natural history of simian foamy virus infection in wild-living chimpanzees. Plos Pathogens. 4: e1000097. PMID 18604273 DOI: 10.1371/Journal.Ppat.1000097  0.439
2008 Keele BF, Giorgi EE, Salazar-Gonzalez JF, Decker JM, Pham KT, Salazar MG, Sun C, Grayson T, Wang S, Li H, Wei X, Jiang C, Kirchherr JL, Gao F, Anderson JA, ... ... Goepfert PA, et al. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. 105: 7552-7. PMID 18490657 DOI: 10.1073/Pnas.0802203105  0.576
2008 Kilby JM, Lee HY, Hazelwood JD, Bansal A, Bucy RP, Saag MS, Shaw GM, Acosta EP, Johnson VA, Perelson AS, Goepfert PA. Treatment response in acute/early infection versus advanced AIDS: equivalent first and second phases of HIV RNA decline. Aids (London, England). 22: 957-62. PMID 18453855 DOI: 10.1097/Qad.0B013E3282Fbd1Da  0.482
2008 Bansal A, Jackson B, West K, Wang S, Lu S, Kennedy JS, Goepfert PA. Multifunctional T-cell characteristics induced by a polyvalent DNA prime/protein boost human immunodeficiency virus type 1 vaccine regimen given to healthy adults are dependent on the route and dose of administration. Journal of Virology. 82: 6458-69. PMID 18448544 DOI: 10.1128/Jvi.00068-08  0.473
2008 Goepfert PA, Lumm W, Farmer P, Matthews P, Prendergast A, Carlson JM, Derdeyn CA, Tang J, Kaslow RA, Bansal A, Yusim K, Heckerman D, Mulenga J, Allen S, Goulder PJ, et al. Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients. The Journal of Experimental Medicine. 205: 1009-17. PMID 18426987 DOI: 10.1084/Jem.20072457  0.517
2008 Crawford H, Prado JG, Leslie A, Hué S, Honeyborne I, Reddy S, Van Der Stok M, Mncube Z, Brander C, Rousseau C, Mullins JI, Kaslow R, Goepfert P, Allen S, Hunter E, et al. Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted gag epitope in chronic human immunodeficiency virus type 1 infection (Journal of Virology (2007) 81, 15, (8346-8351)) Journal of Virology. 82: 3161. DOI: 10.1128/Jvi.02750-07  0.356
2007 Bansal A, Yue L, Conway J, Yusim K, Tang J, Kappes J, Kaslow RA, Wilson CM, Goepfert PA. Immunological control of chronic HIV-1 infection: HLA-mediated immune function and viral evolution in adolescents. Aids (London, England). 21: 2387-97. PMID 18025875 DOI: 10.1097/Qad.0B013E3282F13823  0.582
2007 Brockman MA, Schneidewind A, Lahaie M, Schmidt A, Miura T, Desouza I, Ryvkin F, Derdeyn CA, Allen S, Hunter E, Mulenga J, Goepfert PA, Walker BD, Allen TM. Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A. Journal of Virology. 81: 12608-18. PMID 17728232 DOI: 10.1128/Jvi.01369-07  0.559
2007 Kannanganat S, Kapogiannis BG, Ibegbu C, Chennareddi L, Goepfert P, Robinson HL, Lennox J, Amara RR. Human immunodeficiency virus type 1 controllers but not noncontrollers maintain CD4 T cells coexpressing three cytokines. Journal of Virology. 81: 12071-6. PMID 17728221 DOI: 10.1128/Jvi.01261-07  0.548
2007 Crawford H, Prado JG, Leslie A, Hué S, Honeyborne I, Reddy S, van der Stok M, Mncube Z, Brander C, Rousseau C, Mullins JI, Kaslow R, Goepfert P, Allen S, Hunter E, et al. Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection. Journal of Virology. 81: 8346-51. PMID 17507468 DOI: 10.1128/Jvi.00465-07  0.444
2007 Fu TM, Dubey SA, Mehrotra DV, Freed DC, Trigona WL, Adams-Muhler L, Clair JH, Evans TG, Steigbigel R, Jacobson JM, Goepfert PA, Mulligan MJ, Kalams SA, Rinaldo C, Zhu L, et al. Evaluation of cellular immune responses in subjects chronically infected with HIV type 1. Aids Research and Human Retroviruses. 23: 67-76. PMID 17263635 DOI: 10.1089/Aid.2006.0114  0.597
2007 Sabbaj S, Heath SL, Bansal A, Vohra S, Kilby JM, Zajac AJ, Goepfert PA. Functionally competent antigen-specific CD127(hi) memory CD8+ T cells are preserved only in HIV-infected individuals receiving early treatment. The Journal of Infectious Diseases. 195: 108-17. PMID 17152014 DOI: 10.1086/509510  0.575
2007 Yu XG, Lichterfeld M, Chetty S, Williams KL, Mui SK, Miura T, Frahm N, Feeney ME, Tang Y, Pereyra F, Labute MX, Pfafferott K, Leslie A, Crawford H, Allgaier R, ... ... Goepfert PA, et al. Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes. Journal of Virology. 81: 1619-31. PMID 17121793 DOI: 10.1128/Jvi.01580-06  0.488
2007 Goepfert PA, Tomaras GD, Horton H, Montefiori D, Ferrari G, Deers M, Voss G, Koutsoukos M, Pedneault L, Vandepapeliere P, McElrath MJ, Spearman P, Fuchs JD, Koblin BA, Blattner WA, et al. Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers. Vaccine. 25: 510-8. PMID 17049679 DOI: 10.1016/J.Vaccine.2006.07.050  0.501
2006 Chattopadhyay PK, Price DA, Harper TF, Betts MR, Yu J, Gostick E, Perfetto SP, Goepfert P, Koup RA, De Rosa SC, Bruchez MP, Roederer M. Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry. Nature Medicine. 12: 972-7. PMID 16862156 DOI: 10.1038/Nm1371  0.319
2006 Yu J, Chen H, Horton H, Bansal A, McElrath JM, Reichman R, Goepfert P, Jin X. Interleukin-2 reconstitutes defective human immunodeficiency virus (HIV), and cytomegalovirus (CMV) specific CD8+ T cell proliferation in HIV infection. Journal of Medical Virology. 78: 1147-57. PMID 16847956 DOI: 10.1002/Jmv.20675  0.646
2006 Turnbull EL, Lopes AR, Jones NA, Cornforth D, Newton P, Aldam D, Pellegrino P, Turner J, Williams I, Wilson CM, Goepfert PA, Maini MK, Borrow P. HIV-1 epitope-specific CD8+ T cell responses strongly associated with delayed disease progression cross-recognize epitope variants efficiently. Journal of Immunology (Baltimore, Md. : 1950). 176: 6130-46. PMID 16670322 DOI: 10.4049/Jimmunol.176.10.6130  0.609
2006 Betts MR, Nason MC, West SM, De Rosa SC, Migueles SA, Abraham J, Lederman MM, Benito JM, Goepfert PA, Connors M, Roederer M, Koup RA. HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood. 107: 4781-9. PMID 16467198 DOI: 10.1182/Blood-2005-12-4818  0.638
2006 Bansal A, Gough E, Ritter D, Wilson C, Mulenga J, Allen S, Goepfert PA. Group M-based HIV-1 Gag peptides are frequently targeted by T cells in chronically infected US and Zambian patients. Aids (London, England). 20: 353-60. PMID 16439868 DOI: 10.1097/01.Aids.0000206501.16783.67  0.482
2005 Goepfert PA, Horton H, McElrath MJ, Gurunathan S, Ferrari G, Tomaras GD, Montefiori DC, Allen M, Chiu YL, Spearman P, Fuchs JD, Koblin BA, Blattner WA, Frey S, Keefer MC, et al. High-dose recombinant Canarypox vaccine expressing HIV-1 protein, in seronegative human subjects. The Journal of Infectious Diseases. 192: 1249-59. PMID 16136469 DOI: 10.1086/432915  0.507
2005 Li M, Gao F, Mascola JR, Stamatatos L, Polonis VR, Koutsoukos M, Voss G, Goepfert P, Gilbert P, Greene KM, Bilska M, Kothe DL, Salazar-Gonzalez JF, Wei X, Decker JM, et al. Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies. Journal of Virology. 79: 10108-25. PMID 16051804 DOI: 10.1128/Jvi.79.16.10108-10125.2005  0.514
2005 Fuller MJ, Hildeman DA, Sabbaj S, Gaddis DE, Tebo AE, Shang L, Goepfert PA, Zajac AJ. Cutting edge: emergence of CD127high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help. Journal of Immunology (Baltimore, Md. : 1950). 174: 5926-30. PMID 15879083 DOI: 10.4049/Jimmunol.174.10.5926  0.466
2005 Betts MR, Exley B, Price DA, Bansal A, Camacho ZT, Teaberry V, West SM, Ambrozak DR, Tomaras G, Roederer M, Kilby JM, Tartaglia J, Belshe R, Gao F, Douek DC, ... ... Goepfert P, et al. Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. 102: 4512-7. PMID 15753288 DOI: 10.1073/Pnas.0408773102  0.656
2005 Moore JS, Wu X, Kulhavy R, Tomana M, Novak J, Moldoveanu Z, Brown R, Goepfert PA, Mestecky J. Increased levels of galactose-deficient IgG in sera of HIV-1-infected individuals. Aids (London, England). 19: 381-9. PMID 15750391 DOI: 10.1097/01.Aids.0000161767.21405.68  0.45
2005 Sabbaj S, Ghosh MK, Edwards BH, Leeth R, Decker WD, Goepfert PA, Aldrovandi GM. Breast milk-derived antigen-specific CD8+ T cells: an extralymphoid effector memory cell population in humans. Journal of Immunology (Baltimore, Md. : 1950). 174: 2951-6. PMID 15728507 DOI: 10.4049/Jimmunol.174.5.2951  0.502
2005 Bansal A, Gough E, Sabbaj S, Ritter D, Yusim K, Sfakianos G, Aldrovandi G, Kaslow RA, Wilson CM, Mulligan MJ, Kilby JM, Goepfert PA. CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptides. Aids (London, England). 19: 241-50. PMID 15718834  0.51
2004 Mestecky J, Jackson S, Moldoveanu Z, Nesbit LR, Kulhavy R, Prince SJ, Sabbaj S, Mulligan MJ, Goepfert PA. Paucity of antigen-specific IgA responses in sera and external secretions of HIV-type 1-infected individuals. Aids Research and Human Retroviruses. 20: 972-88. PMID 15585085 DOI: 10.1089/Aid.2004.20.972  0.49
2004 Ferrari G, Neal W, Ottinger J, Jones AM, Edwards BH, Goepfert P, Betts MR, Koup RA, Buchbinder S, McElrath MJ, Tartaglia J, Weinhold KJ. Absence of immunodominant anti-Gag p17 (SL9) responses among Gag CTL-positive, HIV-uninfected vaccine recipients expressing the HLA-A*0201 allele. Journal of Immunology (Baltimore, Md. : 1950). 173: 2126-33. PMID 15265949 DOI: 10.4049/Jimmunol.173.3.2126  0.619
2004 Wright PF, Mestecky J, McElrath MJ, Keefer MC, Gorse GJ, Goepfert PA, Moldoveanu Z, Schwartz D, Spearman PW, El Habib R, Spring MD, Zhu Y, Smith C, Flores J, Weinhold KJ, et al. Comparison of systemic and mucosal delivery of 2 canarypox virus vaccines expressing either HIV-1 genes or the gene for rabies virus G protein. The Journal of Infectious Diseases. 189: 1221-31. PMID 15031791 DOI: 10.1086/382088  0.52
2003 Bansal A, Sabbaj S, Edwards BH, Ritter D, Perkins C, Tang J, Szinger JJ, Weiss H, Goepfert PA, Korber B, Wilson CM, Kaslow RA, Mulligan MJ. T cell responses in HIV type 1-infected adolescent minorities share similar epitope specificities with whites despite significant differences in HLA class I alleles. Aids Research and Human Retroviruses. 19: 1017-26. PMID 14678609 DOI: 10.1089/088922203322588378  0.527
2003 Lindemann D, Goepfert PA. The foamy virus envelope glycoproteins Current Topics in Microbiology and Immunology. 277: 111-129. PMID 12908770 DOI: 10.1007/978-3-642-55701-9_5  0.335
2003 Sabbaj S, Bansal A, Ritter GD, Perkins C, Edwards BH, Gough E, Tang J, Szinger JJ, Korber B, Wilson CM, Kaslow RA, Mulligan MJ, Goepfert PA. Cross-reactive CD8+ T cell epitopes identified in US adolescent minorities. Journal of Acquired Immune Deficiency Syndromes (1999). 33: 426-38. PMID 12869831 DOI: 10.1097/00126334-200308010-00003  0.587
2003 Goepfert PA. Making sense of the HIV immune response. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 11: 4-8. PMID 12717044  0.403
2003 Tussey LG, Nair US, Bachinsky M, Edwards BH, Bakari J, Grimm K, Joyce J, Vessey R, Steigbigel R, Robertson MN, Shiver JW, Goepfert PA. Antigen burden is major determinant of human immunodeficiency virus-specific CD8+ T cell maturation state: potential implications for therapeutic immunization. The Journal of Infectious Diseases. 187: 364-74. PMID 12552420 DOI: 10.1086/367707  0.632
2003 Shaw KL, Lindemann D, Mulligan MJ, Goepfert PA. Foamy virus envelope glycoprotein is sufficient for particle budding and release. Journal of Virology. 77: 2338-48. PMID 12551971 DOI: 10.1128/Jvi.77.4.2338-2348.2003  0.549
2003 Wright PF, Kozlowski PA, Rybczyk GK, Goepfert P, Staats HF, VanCott TC, Trabattoni D, Sannella E, Mestecky J. Detection of mucosal antibodies in HIV type 1-infected individuals. Aids Research and Human Retroviruses. 18: 1291-300. PMID 12487817 DOI: 10.1089/088922202320886334  0.544
2002 Sabbaj S, Edwards BH, Ghosh MK, Semrau K, Cheelo S, Thea DM, Kuhn L, Ritter GD, Mulligan MJ, Goepfert PA, Aldrovandi GM. Human immunodeficiency virus-specific CD8(+) T cells in human breast milk. Journal of Virology. 76: 7365-73. PMID 12097549 DOI: 10.1128/Jvi.76.15.7365-7373.2002  0.615
2002 Gupta K, Hudgens M, Corey L, McElrath MJ, Weinhold K, Montefiori DC, Gorse GJ, Frey SE, Keefer MC, Evans TG, Dolin R, Schwartz DH, Harro C, Graham B, Spearman PW, ... ... Goepfert P, et al. Safety and immunogenicity of a high-titered canarypox vaccine in combination with rgp120 in a diverse population of HIV-1-uninfected adults: AIDS Vaccine Evaluation Group Protocol 022A. Journal of Acquired Immune Deficiency Syndromes (1999). 29: 254-61. PMID 11873074  0.363
2002 Edwards BH, Bansal A, Sabbaj S, Bakari J, Mulligan MJ, Goepfert PA. Magnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma. Journal of Virology. 76: 2298-305. PMID 11836408 DOI: 10.1128/Jvi.76.5.2298-2305.2002  0.565
2002 Gupta K, Hudgens M, Corey L, McElrath MJ, Weinhold K, Montefiori DC, Gorse GJ, Frey SE, Keefer MC, Evans TG, Dolin R, Schwartz DH, Harro C, Graham B, Spearman PW, ... ... Goepfert P, et al. Safety and Immunogenicity of a High-Titered Canarypox Vaccine in Combination With rgp120 in a Diverse Population of HIV-1–Uninfected Adults: AIDS Vaccine Evaluation Group Protocol 022A Jaids Journal of Acquired Immune Deficiency Syndromes. 29: 254-261. DOI: 10.1097/00042560-200203010-00005  0.465
2001 Ferrari G, Neal W, Jones A, Olender N, Ottinger J, Ha R, McElrath MJ, Goepfert P, Weinhold KJ. CD8 CTL responses in vaccines: emerging patterns of HLA restriction and epitope recognition. Immunology Letters. 79: 37-45. PMID 11595288 DOI: 10.1016/S0165-2478(01)00264-4  0.51
2001 Kaslow RA, Rivers C, Tang J, Bender TJ, Goepfert PA, El Habib R, Weinhold K, Mulligan MJ, Clements-Mann ML, Schwartz D, Belshe R, Gorse G, Frey S, Dolin R, Keefer M, et al. Polymorphisms in HLA class I genes associated with both favorable prognosis of human immunodeficiency virus (HIV) type 1 infection and positive cytotoxic T-lymphocyte responses to ALVAC-HIV recombinant canarypox vaccines Journal of Virology. 75: 8681-8689. PMID 11507213 DOI: 10.1128/Jvi.75.18.8681-8689.2001  0.606
2001 Evans TG, McElrath MJ, Matthews T, Montefiori D, Weinhold K, Wolff M, Keefer MC, Kallas EG, Corey L, Gorse GJ, Belshe R, Graham BS, Spearman PW, Schwartz D, Mulligan MJ, ... Goepfert P, et al. QS-21 promotes an adjuvant effect allowing for reduced antigen dose during HIV-1 envelope subunit immunization in humans. Vaccine. 19: 2080-91. PMID 11228380 DOI: 10.1016/S0264-410X(00)00415-1  0.414
2001 Corey L, Mulligan M, Goepfert P, Sabbaj S, Clements-Mann ML, Harrow C, Schwartz D, Dolin R, Evans T, Keefer M, Belshe R, Gorse G, Frey S, McElrath J, Graham B, et al. Cellular and humoral immune responses to a canarypox vaccine containing human immunodeficiency virus type 1 env, gag, and pro in combination with RGP120 Journal of Infectious Diseases. 183: 563-570. PMID 11170981 DOI: 10.1086/318523  0.607
2000 Goepfert PA, Bansal A, Edwards BH, Ritter GD, Tellez I, McPherson SA, Sabbaj S, Mulligan MJ. A significant number of human immunodeficiency virus epitope-specific cytotoxic T lymphocytes detected by tetramer binding do not produce gamma interferon. Journal of Virology. 74: 10249-55. PMID 11024158 DOI: 10.1128/Jvi.74.21.10249-10255.2000  0.565
2000 Kilby JM, Goepfert PA, Miller AP, Gnann JW, Sillers M, Saag MS, Bucy RP. Recurrence of the acute HIV syndrome after interruption of antiretroviral therapy in a patient with chronic HIV infection: A case report. Annals of Internal Medicine. 133: 435-8. PMID 10975961 DOI: 10.7326/0003-4819-133-6-200009190-00011  0.511
2000 Bansal A, Shaw KL, Edwards BH, Goepfert PA, Mulligan MJ. Characterization of the R572T point mutant of a putative cleavage site in human foamy virus Env. Journal of Virology. 74: 2949-54. PMID 10684317 DOI: 10.1128/Jvi.74.6.2949-2954.2000  0.595
1999 Goepfert PA, Shaw K, Wang G, Bansal A, Edwards BH, Mulligan MJ. An endoplasmic reticulum retrieval signal partitions human foamy virus maturation to intracytoplasmic membranes Journal of Virology. 73: 7210-7217. PMID 10438808 DOI: 10.1128/Jvi.73.9.7210-7217.1999  0.575
1997 Goepfert PA, Shaw KL, Ritter GD, Mulligan MJ. A sorting motif localizes the foamy virus glycoprotein to the endoplasmic reticulum. Journal of Virology. 71: 778-84. PMID 8985416 DOI: 10.1128/Jvi.71.1.778-784.1997  0.555
1996 Goepfert PA, Ritter J, Peng X, Gbakima AA, Zhang Y, Mulligan MJ. Analysis of West African hunters for foamy virus infections Aids Research and Human Retroviruses. 12: 1725-1730. PMID 8959250 DOI: 10.1089/Aid.1996.12.1725  0.392
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