Stephen C. Peiper - Publications

Affiliations: 
University of Louisville, Louisville, KY, United States 
Area:
Molecular Biology, Cell Biology, Microbiology Biology

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Gargano SM, Badjatia N, Nikolaus Y, Peiper SC, Wang ZX. Characterization and Clinical Significance of EIF1AX Mutations and Co-Mutations in Cytologically Indeterminate Thyroid Nodules: A 5-Year Retrospective Analysis. Acta Medica Academica. 50: 4-12. PMID 34075760 DOI: 10.5644/ama2006-124.322  0.369
2020 Shen H, Wang GC, Li X, Ge X, Wang M, Shi ZM, Bhardwaj V, Wang ZX, Zinner RG, Peiper SC, Aplin AE, Jiang BH, He J. S6K1 blockade overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer. Oncogene. PMID 33037411 DOI: 10.1038/s41388-020-01497-4  0.402
2020 Jin R, Pettengill MA, Hartnett NL, Auerbach HE, Peiper SC, Wang Z. Commercial SARS-CoV-2 Molecular Assays: Superior Analytical Sensitivity of cobas SARS-CoV-2 Relative to NxTAG Cov Extended Panel and ID NOW COVID-19 Test. Archives of Pathology & Laboratory Medicine. PMID 32649229 DOI: 10.5858/Arpa.2020-0283-Sa  0.461
2020 Al Saiegh F, Ghosh R, Leibold A, Avery MB, Schmidt RF, Theofanis T, Mouchtouris N, Philipp L, Peiper SC, Wang ZX, Rincon F, Tjoumakaris SI, Jabbour P, Rosenwasser RH, Gooch MR. Status of SARS-CoV-2 in cerebrospinal fluid of patients with COVID-19 and stroke. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 32354770 DOI: 10.1136/Jnnp-2020-323522  0.437
2018 Liao L, Liu ZZ, Langbein L, Cai W, Cho EA, Na J, Niu X, Jiang W, Zhong Z, Cai WL, Jagannathan G, Dulaimi E, Testa JR, Uzzo RG, Wang Y, ... ... Peiper SC, et al. Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer. Elife. 7. PMID 30355451 DOI: 10.7554/Elife.37925  0.308
2018 Neill T, Andreuzzi E, Wang ZX, Peiper SC, Mongiat M, Iozzo RV. Endorepellin remodels the endothelial transcriptome toward a pro-autophagic and pro-mitophagic gene signature. The Journal of Biological Chemistry. PMID 29921586 DOI: 10.1074/Jbc.Ra118.002934  0.506
2016 Brody JR, Yabar CS, Zarei M, Bender J, Matrisian LM, Rahib L, Heartwell C, Mason K, Yeo CJ, Peiper SC, Jiang W, Varieur K, Madhavan S, Petricoin E, Fortuna D, et al. Identification of a novel metabolic-related mutation (IDH1) in metastatic pancreatic cancer. Cancer Biology & Therapy. 0. PMID 27466707 DOI: 10.1080/15384047.2016.1210743  0.474
2016 Buraschi S, Xu SQ, Stefanello M, Moskalev I, Morcavallo A, Genua M, Tanimoto R, Birbe R, Peiper SC, Gomella LG, Belfiore A, Black PC, Iozzo RV, Morrione A. Suppression of progranulin expression inhibits bladder cancer growth and sensitizes cancer cells to cisplatin. Oncotarget. PMID 27220888 DOI: 10.18632/Oncotarget.9556  0.305
2016 Buraschi S, Xu S, Stefanello M, Moskalev I, Morcavallo A, Genua M, Tanimoto R, Neill T, Peiper SC, Gomella LG, Belfiore A, Black PC, Iozzo RV, Morrione A. Abstract 698: Progranulin targeting in urothelial cancer cells inhibits motility, tumor growthin vitroandin vivoand sensitizes cells to cisplatin Cancer Research. 76: 698-698. DOI: 10.1158/1538-7445.Am2016-698  0.32
2016 Palmer J, Shukla G, Mollaee M, Sharma D, Skowronski J, Bhamidipati D, Champ C, Glass J, Kim L, Judy K, Evans J, Farrell C, Andrews D, Peiper S, Shi W, et al. NIMG-67. PRE-RADIATION TUMOR PROGRESSION IMPROVES PROGNOSTIC STRATIFICATION IN GLIOBLASTOMA PATIENTS Neuro-Oncology. 18: vi139-vi139. DOI: 10.1093/Neuonc/Now212.578  0.445
2016 Peiper SC, Johnson E, Wang Z. Sequencing the Snark Comparison of Whole-Genome Sequencing Strategies for the Detection of Somatic Mutations in Cancer Clinical Omics. 3: 24-26. DOI: 10.1089/Clinomi.03.05.09  0.453
2016 Peiper SC, Wang Z. Breast Cancer YAPI (Yet Another Prognostic Indicator) Revisited: American Society of Clinical Oncology Recommendations Clinical Omics. 3: 22-23. DOI: 10.1089/Clinomi.03.04.08  0.438
2016 Peiper SC, Wang Z. Beyond A C G T Clinical Omics. 3: 18-19. DOI: 10.1089/Clinomi.03.01.07  0.444
2015 Xu SQ, Buraschi S, Morcavallo A, Genua M, Shirao T, Peiper SC, Gomella LG, Birbe R, Belfiore A, Iozzo RV, Morrione A. A novel role for drebrin in regulating progranulin bioactivity in bladder cancer. Oncotarget. 6: 10825-39. PMID 25839164 DOI: 10.18632/Oncotarget.3424  0.31
2015 Uppal G, Ly V, Wang ZX, Bajaj R, Solomides CC, Banks PM, Medeiros LJ, Peiper SC, Gong JZ. The utility of BRAF V600E mutation-specific antibody VE1 for the diagnosis of hairy cell leukemia. American Journal of Clinical Pathology. 143: 120-5. PMID 25511150 DOI: 10.1309/Ajcpqlq89Vxtvwkn  0.459
2015 Simen BB, Yin L, Goswami CP, Davis KO, Bajaj R, Gong JZ, Peiper SC, Johnson ES, Wang ZX. Validation of a next-generation-sequencing cancer panel for use in the clinical laboratory. Archives of Pathology & Laboratory Medicine. 139: 508-17. PMID 25356985 DOI: 10.5858/Arpa.2013-0710-Oa  0.471
2015 Mardekian SK, Solomides CC, Gong JZ, Peiper SC, Wang ZX, Bajaj R. Comparison of Chromogenic In Situ Hybridization and Fluorescence In Situ Hybridization for the Evaluation of MDM2 Amplification in Adipocytic Tumors. Journal of Clinical Laboratory Analysis. 29: 462-8. PMID 25132285 DOI: 10.1002/Jcla.21794  0.46
2015 Xu S, Buraschi S, Morcavallo A, Genua M, Shirao T, Peiper SC, Gomella LG, Belfiore A, Iozzo RV, Morrione A. Abstract 4945: A novel role for drebrin in regulating progranulin bioactivity in bladder cancer Cancer Research. 75: 4945-4945. DOI: 10.1158/1538-7445.Am2015-4945  0.302
2015 Ly V, Bajaj R, Gong J, Wang Z, Peiper S, Uppal G. t(3;8)(q26;q24) With MYC Rearrangement in Acute Myeloid Leukemia: A Case Report American Journal of Clinical Pathology. 144: A119-A119. DOI: 10.1093/Ajcp/144.Suppl2.119  0.438
2015 Peiper SC, Wang Z. Molecularly Targeted Agents in Personalized Cancer Therapy and Diagnostics Clinical Omics. 2: 18-19. DOI: 10.1089/Clinomi.02.11.07  0.438
2015 Peiper SC, Wang ZX. The Pons Asinorum of Diagnostic Genomics Genetic Engineering and Biotechnology News. 35. DOI: 10.1089/Clinomi.02.10.08  0.415
2014 Schneider EH, Fowler SC, Lionakis MS, Swamydas M, Holmes G, Diaz V, Munasinghe J, Peiper SC, Gao JL, Murphy PM. Regulation of motor function and behavior by atypical chemokine receptor 1. Behavior Genetics. 44: 498-515. PMID 24997773 DOI: 10.1007/S10519-014-9665-7  0.301
2014 Jamal SE, Li S, Bajaj R, Wang Z, Kenyon L, Glass J, Pang CS, Bhagavathi S, Peiper SC, Gong JZ. Primary central nervous system Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly: a clinicopathologic study of five cases. Brain Tumor Pathology. 31: 265-73. PMID 24399201 DOI: 10.1007/S10014-013-0173-X  0.464
2013 Misu R, Oishi S, Setsuda S, Noguchi T, Kaneda M, Ohno H, Evans B, Navenot JM, Peiper SC, Fujii N. Characterization of the receptor binding residues of kisspeptins by positional scanning using peptide photoaffinity probes. Bioorganic & Medicinal Chemistry Letters. 23: 2628-31. PMID 23522565 DOI: 10.1016/J.Bmcl.2013.02.098  0.335
2013 Gong P, Metrebian F, Dulau-Florea A, Wang ZX, Bajaj R, Gulati G, Peiper SC, Gong JZ. Aberrant expression of CD56 on granulocytes and monocytes in myeloproliferative neoplasm Journal of Hematopathology. 6: 127-134. DOI: 10.1007/S12308-013-0190-Z  0.469
2012 Solomides CC, Evans BJ, Navenot JM, Vadigepalli R, Peiper SC, Wang ZX. MicroRNA profiling in lung cancer reveals new molecular markers for diagnosis. Acta Cytologica. 56: 645-54. PMID 23207443 DOI: 10.1159/000343473  0.454
2012 Buraschi S, Neill T, Owens RT, Iniguez LA, Purkins G, Vadigepalli R, Evans B, Schaefer L, Peiper SC, Wang ZX, Iozzo RV. Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model. Plos One. 7: e45559. PMID 23029096 DOI: 10.1371/Journal.Pone.0045559  0.505
2012 Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Yano Y, Matsuzaki K, Navenot JM, Peiper SC, Fujii N. Paradoxical downregulation of CXC chemokine receptor 4 induced by polyphemusin II-derived antagonists. Bioconjugate Chemistry. 23: 1259-65. PMID 22486464 DOI: 10.1021/Bc300084H  0.372
2012 Navenot JM, Evans B, Oishi S, Setsuda S, Fujii N, Peiper SC. The metastasis suppressor KISS1 lacks antimetastatic activity in the C8161.9 xenograft model of melanoma. Melanoma Research. 22: 140-50. PMID 22395416 DOI: 10.1097/Cmr.0B013E328350Fa07  0.311
2011 Iozzo RV, Buraschi S, Genua M, Xu SQ, Solomides CC, Peiper SC, Gomella LG, Owens RC, Morrione A. Decorin antagonizes IGF receptor I (IGF-IR) function by interfering with IGF-IR activity and attenuating downstream signaling. The Journal of Biological Chemistry. 286: 34712-21. PMID 21840990 DOI: 10.1074/Jbc.M111.262766  0.305
2010 Mandawat A, Fiskus W, Buckley KM, Robbins K, Rao R, Balusu R, Navenot JM, Wang ZX, Ustun C, Chong DG, Atadja P, Fujii N, Peiper SC, Bhalla K. Pan-histone deacetylase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists. Blood. 116: 5306-15. PMID 20810927 DOI: 10.1182/Blood-2010-05-284414  0.522
2010 Sharma S, Free A, Mei Y, Peiper SC, Wang Z, Cowell JK. Distinct molecular signatures in pediatric infratentorial glioblastomas defined by aCGH. Experimental and Molecular Pathology. 89: 169-74. PMID 20621092 DOI: 10.1016/J.Yexmp.2010.06.009  0.396
2010 Nishizawa K, Nishiyama H, Oishi S, Tanahara N, Kotani H, Mikami Y, Toda Y, Evans BJ, Peiper SC, Saito R, Watanabe J, Fujii N, Ogawa O. Fluorescent imaging of high-grade bladder cancer using a specific antagonist for chemokine receptor CXCR4. International Journal of Cancer. Journal International Du Cancer. 127: 1180-7. PMID 20039317 DOI: 10.1002/Ijc.25145  0.327
2010 Kline J, Chervoneva I, Freydin B, solomides C, Witkiewicz AK, Martin C, Peiper S. Insulin-like growth factor receptor 1(IGFIR) is overexpressed in a subset of triple negative breast cancers Clinical Cancer Research. 16. DOI: 10.1158/Diag-10-A29  0.323
2009 Tanaka T, Nomura W, Narumi T, Esaka A, Oishi S, Ohashi N, Itotani K, Evans BJ, Wang ZX, Peiper SC, Fujii N, Tamamura H. Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids. Organic & Biomolecular Chemistry. 7: 3805-9. PMID 19707686 DOI: 10.1039/B908286G  0.505
2009 Evans BJ, Wang Z, Broach JR, Oishi S, Fujii N, Peiper SC. Expression of CXCR4, a G-protein-coupled receptor for CXCL12 in yeast identification of new-generation inverse agonists. Methods in Enzymology. 460: 399-412. PMID 19446737 DOI: 10.1016/S0076-6879(09)05220-3  0.548
2009 Tamamura H, Tanaka T, Tsutsumi H, Ohashi N, Hiramatsu K, Araki T, Ojida A, Hamachi I, Wang Z, Peiper SC, Trent JO, Ueda S, Oishi S, Fujii N. Development of chemokine receptor CXCR4 antagonists using bio-mimetic strategy. Advances in Experimental Medicine and Biology. 611: 145-6. PMID 19400132 DOI: 10.1007/978-0-387-73657-0_65  0.504
2009 Navenot JM, Fujii N, Peiper SC. Activation of Rho and Rho-associated kinase by GPR54 and KiSS1 metastasis suppressor gene product induces changes of cell morphology and contributes to apoptosis. Molecular Pharmacology. 75: 1300-6. PMID 19286835 DOI: 10.1124/Mol.109.055095  0.342
2009 Navenot JM, Fujii N, Peiper SC. KiSS1 metastasis suppressor gene product induces suppression of tyrosine kinase receptor signaling to Akt, tumor necrosis factor family ligand expression, and apoptosis. Molecular Pharmacology. 75: 1074-83. PMID 19201817 DOI: 10.1124/Mol.108.054270  0.363
2008 Tomita K, Oishi S, Ohno H, Peiper SC, Fujii N. Development of novel G-protein-coupled receptor 54 agonists with resistance to degradation by matrix metalloproteinase. Journal of Medicinal Chemistry. 51: 7645-9. PMID 19007202 DOI: 10.1021/Jm800930W  0.314
2008 Evans BJ, Wang Z, Mobley L, Khosravi D, Fujii N, Navenot JM, Peiper SC. Physical association of GPR54 C-terminal with protein phosphatase 2A. Biochemical and Biophysical Research Communications. 377: 1067-71. PMID 18977201 DOI: 10.1016/J.Bbrc.2008.10.108  0.496
2008 Ueda S, Kato M, Inuki S, Ohno H, Evans B, Wang ZX, Peiper SC, Izumi K, Kodama E, Matsuoka M, Nagasawa H, Oishi S, Fujii N. Identification of novel non-peptide CXCR4 antagonists by ligand-based design approach. Bioorganic & Medicinal Chemistry Letters. 18: 4124-9. PMID 18539453 DOI: 10.1016/J.Bmcl.2008.05.092  0.492
2008 Romero-Sánchez M, Peiper SC, Evans B, Wang Z, Catasús L, Ribe A, Prat J, Giri JG. Expression profile of heptahelical putative membrane progesterone receptors in epithelial ovarian tumors. Human Pathology. 39: 1026-33. PMID 18479732 DOI: 10.1016/J.Humpath.2007.11.007  0.531
2008 Oishi S, Masuda R, Evans B, Ueda S, Goto Y, Ohno H, Hirasawa A, Tsujimoto G, Wang Z, Peiper SC, Naito T, Kodama E, Matsuoka M, Fujii N. Synthesis and application of fluorescein- and biotin-labeled molecular probes for the chemokine receptor CXCR4. Chembiochem : a European Journal of Chemical Biology. 9: 1154-8. PMID 18412193 DOI: 10.1002/Cbic.200700761  0.523
2008 Jillella AP, Mandawat A, Fiskus W, Rao R, Wang Z, Wang Y, Atadja P, Fujii N, Peiper S, Bhalla KN. Effect of pan-histone deacetylase inhibitor panobinostat (LBH589) on CXCR4 levels and signaling and on anti-leukemia activity in combination with CXCR4 antagonists Journal of Clinical Oncology. 26: 14541-14541. DOI: 10.1200/Jco.2008.26.15_Suppl.14541  0.318
2007 Lipan O, Navenot JM, Wang Z, Huang L, Peiper SC. Heat shock response in CHO mammalian cells is controlled by a nonlinear stochastic process. Plos Computational Biology. 3: 1859-70. PMID 17922567 DOI: 10.1371/Journal.Pcbi.0030187  0.451
2007 Zhang W, Navenot JM, Frilot NM, Fujii N, Peiper SC. Association of nucleophosmin negatively regulates CXCR4-mediated G protein activation and chemotaxis. Molecular Pharmacology. 72: 1310-21. PMID 17715399 DOI: 10.1124/Mol.107.037119  0.378
2007 Tomita K, Oishi S, Cluzeau J, Ohno H, Navenot JM, Wang ZX, Peiper SC, Akamatsu M, Fujii N. SAR and QSAR studies on the N-terminally acylated pentapeptide agonists for GPR54. Journal of Medicinal Chemistry. 50: 3222-8. PMID 17579384 DOI: 10.1021/Jm070064L  0.514
2007 Cluzeau J, Oishi S, Ohno H, Wang Z, Evans B, Peiper SC, Fujii N. Design and synthesis of all diastereomers of cyclic pseudo-dipeptides as mimics of cyclic CXCR4 pentapeptide antagonists. Organic & Biomolecular Chemistry. 5: 1915-23. PMID 17551641 DOI: 10.1039/B702649H  0.466
2007 Nash KT, Phadke PA, Navenot JM, Hurst DR, Accavitti-Loper MA, Sztul E, Vaidya KS, Frost AR, Kappes JC, Peiper SC, Welch DR. Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy. Journal of the National Cancer Institute. 99: 309-21. PMID 17312308 DOI: 10.1093/Jnci/Djk053  0.317
2007 Ueda S, Oishi S, Wang ZX, Araki T, Tamamura H, Cluzeau J, Ohno H, Kusano S, Nakashima H, Trent JO, Peiper SC, Fujii N. Structure-activity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists: disclosing the importance of side-chain and backbone functionalities. Journal of Medicinal Chemistry. 50: 192-8. PMID 17228861 DOI: 10.1021/Jm0607350  0.501
2007 Sui Y, Yang Z, Xiong S, Zhang L, Blanchard KL, Peiper SC, Dynan WS, Tuan D, Ko L. Gene amplification and associated loss of 5′ regulatory sequences of CoAA in human cancers Oncogene. 26: 822-835. PMID 16878147 DOI: 10.1038/Sj.Onc.1209847  0.315
2007 Napier KB, Wang ZX, Peiper SC, Trent JO. CCR5 interactions with the variable 3 loop of gp120. Journal of Molecular Modeling. 13: 29-41. PMID 16721558 DOI: 10.1007/S00894-006-0117-Z  0.529
2007 Mandawat A, Fiskus W, Jakubowski A, Rao R, Wang Z, Fernandez P, Wang Y, Lee P, Jillela A, Atadja P, Fujii N, Peiper SC, Bhalla K. Pan-Histone Deacetylase (HDAC) Inhibitor LBH589 Depletes CXCR4 Levels and Signaling, Exerting Synergistic Anti-Leukemia Activity in Combination with CXCR4 Antagonists. Blood. 110: 537-537. DOI: 10.1182/Blood.V110.11.537.537  0.51
2006 Tomita K, Niida A, Oishi S, Ohno H, Cluzeau J, Navenot JM, Wang ZX, Peiper SC, Fujii N. Structure-activity relationship study on small peptidic GPR54 agonists. Bioorganic & Medicinal Chemistry. 14: 7595-603. PMID 16879969 DOI: 10.1016/J.Bmc.2006.07.009  0.538
2006 Navenot JM, Wang ZX, Peiper SC. Characterization of constitutively active mutants of G protein-coupled receptors. Methods in Molecular Biology (Clifton, N.J.). 332: 129-39. PMID 16878689 DOI: 10.1385/1-59745-048-0:129  0.516
2006 Wang ZX, Broach JR, Peiper SC. Functional expression of CXCR4 in Saccharomyces cerevisiae in the development of powerful tools for the pharmacological characterization of CXCR4. Methods in Molecular Biology (Clifton, N.J.). 332: 115-27. PMID 16878688 DOI: 10.1385/1-59745-048-0:115  0.536
2006 Tamamura H, Tsutsumi H, Masuno H, Mizokami S, Hiramatsu K, Wang Z, Trent JO, Nakashima H, Yamamoto N, Peiper SC, Fujii N. Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs. Organic & Biomolecular Chemistry. 4: 2354-7. PMID 16763678 DOI: 10.1039/B603818B  0.498
2006 Niida A, Tanigaki H, Inokuchi E, Sasaki Y, Oishi S, Ohno H, Tamamura H, Wang Z, Peiper SC, Kitaura K, Otaka A, Fujii N. Stereoselective synthesis of 3,6-disubstituted-3,6-dihydropyridin-2-ones as potential diketopiperazine mimetics using organocopper-mediated anti-SN2' reactions and their use in the preparation of low-molecule CXCR4 antagonists. The Journal of Organic Chemistry. 71: 3942-51. PMID 16674071 DOI: 10.1021/Jo060390T  0.473
2006 Niida A, Wang Z, Tomita K, Oishi S, Tamamura H, Otaka A, Navenot JM, Broach JR, Peiper SC, Fujii N. Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity. Bioorganic & Medicinal Chemistry Letters. 16: 134-7. PMID 16242330 DOI: 10.1016/J.Bmcl.2005.09.054  0.544
2005 Tamamura H, Esaka A, Ogawa T, Araki T, Ueda S, Wang Z, Trent JO, Tsutsumi H, Masuno H, Nakashima H, Yamamoto N, Peiper SC, Otaka A, Fujii N. Structure-activity relationship studies on CXCR4 antagonists having cyclic pentapeptide scaffolds. Organic & Biomolecular Chemistry. 3: 4392-4. PMID 16327900 DOI: 10.1039/B513145F  0.496
2005 Navenot JM, Wang Z, Chopin M, Fujii N, Peiper SC. Kisspeptin-10-induced signaling of GPR54 negatively regulates chemotactic responses mediated by CXCR4: a potential mechanism for the metastasis suppressor activity of kisspeptins. Cancer Research. 65: 10450-6. PMID 16288036 DOI: 10.1158/0008-5472.Can-05-1757  0.528
2005 Hu Q, Napier KB, Trent JO, Wang Z, Taylor S, Griffin GE, Peiper SC, Shattock RJ. Restricted variable residues in the C-terminal segment of HIV-1 V3 loop regulate the molecular anatomy of CCR5 utilization. Journal of Molecular Biology. 350: 699-712. PMID 15964018 DOI: 10.1016/J.Jmb.2005.05.024  0.507
2005 Tamamura H, Araki T, Ueda S, Wang Z, Oishi S, Esaka A, Trent JO, Nakashima H, Yamamoto N, Peiper SC, Otaka A, Fujii N. Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds. Journal of Medicinal Chemistry. 48: 3280-9. PMID 15857134 DOI: 10.1021/Jm050009H  0.506
2005 Tamamura H, Hiramatsu K, Ueda S, Wang Z, Kusano S, Terakubo S, Trent JO, Peiper SC, Yamamoto N, Nakashima H, Otaka A, Fujii N. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. Journal of Medicinal Chemistry. 48: 380-91. PMID 15658852 DOI: 10.1021/Jm049429H  0.469
2005 Bhonsle JB, Wang ZX, Tamamura H, Fujii N, Peiper SC, Trent JO. A simple, automated quasi-4D-QSAR, quasi-multi way PLS approach to develop highly predictive QSAR models for highly flexible CXCR4 inhibitor cyclic pentapeptide ligands using scripted common molecular modeling tools Qsar and Combinatorial Science. 24: 620-630. DOI: 10.1002/Qsar.200430912  0.473
2004 Tamamura H, Mizumoto M, Hiramatsu K, Kusano S, Terakubo S, Yamamoto N, Trent JO, Wang Z, Peiper SC, Nakashima H, Otaka A, Fujii N. Topochemical exploration of potent compounds using retro-enantiomer libraries of cyclic pentapeptides. Organic & Biomolecular Chemistry. 2: 1255-7. PMID 15064805 DOI: 10.1039/B401485P  0.476
2004 Masui T, Doi R, Mori T, Toyoda E, Koizumi M, Kami K, Ito D, Peiper SC, Broach JR, Oishi S, Niida A, Fujii N, Imamura M. Metastin and its variant forms suppress migration of pancreatic cancer cells. Biochemical and Biophysical Research Communications. 315: 85-92. PMID 15013429 DOI: 10.1016/J.Bbrc.2004.01.021  0.329
2003 Tamamura H, Hiramatsu K, Mizumoto M, Ueda S, Kusano S, Terakubo S, Akamatsu M, Yamamoto N, Trent JO, Wang Z, Peiper SC, Nakashima H, Otaka A, Fujii N. Enhancement of the T140-based pharmacophores leads to the development of more potent and bio-stable CXCR4 antagonists. Organic & Biomolecular Chemistry. 1: 3663-9. PMID 14649897 DOI: 10.1039/B306613B  0.517
2003 Tamamura H, Hiramatsu K, Kusano aS, Terakubo S, Yamamoto N, Trent JO, Wang Z, Peiper SC, Nakashima H, Otaka A, Fujii N. Synthesis of potent CXCR4 inhibitors possessing low cytotoxicity and improved biostability based on T140 derivatives. Organic & Biomolecular Chemistry. 1: 3656-62. PMID 14649896 DOI: 10.1039/B306473P  0.515
2003 Trent JO, Wang ZX, Murray JL, Shao W, Tamamura H, Fujii N, Peiper SC. Lipid bilayer simulations of CXCR4 with inverse agonists and weak partial agonists. The Journal of Biological Chemistry. 278: 47136-44. PMID 12958314 DOI: 10.1074/Jbc.M307850200  0.519
2003 Fujii N, Oishi S, Hiramatsu K, Araki T, Ueda S, Tamamura H, Otaka A, Kusano S, Terakubo S, Nakashima H, Broach JA, Trent JO, Wang ZX, Peiper SC. Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries. Angewandte Chemie (International Ed. in English). 42: 3251-3. PMID 12876735 DOI: 10.1002/Anie.200351024  0.481
2003 Alvarez Arias D, Navenot JM, Zhang WB, Broach J, Peiper SC. Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2. The Journal of Biological Chemistry. 278: 36513-21. PMID 12837756 DOI: 10.1074/Jbc.M303739200  0.373
2003 Sun D, Zhang Y, Wei B, Peiper SC, Shao H, Kaplan HJ. Encephalitogenic activity of truncated myelin oligodendrocyte glycoprotein (MOG) peptides and their recognition by CD8+ MOG-specific T cells on oligomeric MHC class I molecules. International Immunology. 15: 261-8. PMID 12578856 DOI: 10.1093/Intimm/Dxg023  0.303
2002 Libura J, Drukala J, Majka M, Tomescu O, Navenot JM, Kucia M, Marquez L, Peiper SC, Barr FG, Janowska-Wieczorek A, Ratajczak MZ. CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion. Blood. 100: 2597-606. PMID 12239174 DOI: 10.1182/Blood-2002-01-0031  0.342
2002 Zhang WB, Navenot JM, Haribabu B, Tamamura H, Hiramatu K, Omagari A, Pei G, Manfredi JP, Fujii N, Broach JR, Peiper SC. A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists. The Journal of Biological Chemistry. 277: 24515-21. PMID 11923301 DOI: 10.1074/Jbc.M200889200  0.384
2002 Du J, Luan J, Liu H, Daniel TO, Peiper S, Chen TS, Yu Y, Horton LW, Nanney LB, Strieter RM, Richmond A. Potential role for Duffy antigen chemokine-binding protein in angiogenesis and maintenance of homeostasis in response to stress. Journal of Leukocyte Biology. 71: 141-53. PMID 11781390 DOI: 10.1189/Jlb.71.1.141  0.321
2001 Navenot JM, Wang ZX, Trent JO, Murray JL, Hu QX, DeLeeuw L, Moore PS, Chang Y, Peiper SC. Molecular anatomy of CCR5 engagement by physiologic and viral chemokines and HIV-1 envelope glycoproteins: Differences in primary structural requirements for RANTES, MIP-1α, and vMIP-II binding Journal of Molecular Biology. 313: 1181-1193. PMID 11700073 DOI: 10.1006/Jmbi.2001.5086  0.315
2001 Tanaka R, Yoshida A, Murakami T, Baba E, Lichtenfeld J, Omori T, Kimura T, Tsurutani N, Fujii N, Wang ZX, Peiper SC, Yamamoto N, Tanaka Y. Unique monoclonal antibody recognizing the third extracellular loop of CXCR4 induces lymphocyte agglutination and enhances human immunodeficiency virus type 1-mediated syncytium formation and productive infection Journal of Virology. 75: 11534-11543. PMID 11689635 DOI: 10.1128/Jvi.75.23.11534-11543.2001  0.302
2001 Tamamura H, Sugioka M, Odagaki Y, Omagari A, Kan Y, Oishi S, Nakashima H, Yamamoto N, Peiper SC, Hamanaka N, Otaka A, Fujii N. Conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity Bioorganic and Medicinal Chemistry Letters. 11: 359-362. PMID 11212110 DOI: 10.1016/S0960-894X(00)00664-8  0.323
2000 Tamamura H, Omagari A, Oishi S, Kanamoto T, Yamamoto N, Peiper SC, Nakashima H, Otaka A, Fujii N. Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads to development of effective anti-HIV agents with very high selectivity indexes Bioorganic and Medicinal Chemistry Letters. 10: 2633-2637. PMID 11128640 DOI: 10.1016/S0960-894X(00)00535-7  0.308
2000 Hu Q, Trent JO, Tomaras GD, Wang Z, Murray JL, Conolly SM, Navenot JM, Barry AP, Greenberg ML, Peiper SC. Identification of ENV determinants in V3 that influence the molecular anatomy of CCR5 utilization. Journal of Molecular Biology. 302: 359-75. PMID 10970739 DOI: 10.1006/Jmbi.2000.4076  0.314
2000 Tecimer T, Dlott J, Chuntharapai A, Martin AW, Peiper SC. Expression of the chemokine receptor CXCR2 in normal and neoplastic neuroendocrine cells Archives of Pathology and Laboratory Medicine. 124: 520-525. PMID 10747307 DOI: 10.1043/0003-9985(2000)124<0520:Eotcrc>2.0.Co;2  0.334
1999 Murakami T, Zhang TY, Koyanagi Y, Tanaka Y, Kim J, Suzuki Y, Minoguchi S, Tamamura H, Waki M, Matsumoto A, Fujii N, Shida H, Hoxie JA, Peiper SC, Yamamoto N. Inhibitory mechanism of the CXCR4 antagonist T22 against human immunodeficiency virus type 1 infection Journal of Virology. 73: 7489-7496. PMID 10438838 DOI: 10.1128/Jvi.76.2.933.2002  0.316
1999 Doranz BJ, Orsini MJ, Turner JD, Hoffman TL, Berson JF, Hoxie JA, Peiper SC, Brass LF, Doms RW. Identification of CXCR4 domains that support coreceptor and chemokine receptor functions. Journal of Virology. 73: 2752-61. PMID 10074122 DOI: 10.1128/Jvi.73.4.2752-2761.1999  0.352
1999 LiWang AC, Cao JJ, Zheng H, Lu Z, Peiper SC, LiWang PJ. Dynamics study on the anti-human immunodeficiency virus chemokine viral macrophage-inflammatory protein-II (VMIP-II) reveals a fully monomeric protein Biochemistry. 38: 442-453. PMID 9890927 DOI: 10.1021/Bi9812726  0.302
1998 Zhao SF, Li W, Dornadula G, Dicker D, Hoxie J, Peiper SC, Pomerantz RJ, Duan LX. Chemokine receptors and the molecular basis for human immunodeficiency virus type 1 entry into peripheral hematopoietic stem cells and their progeny Journal of Infectious Diseases. 178: 1623-1634. PMID 9815214 DOI: 10.1086/314506  0.319
1998 Willett BJ, Adema K, Heveker N, Brelot A, Picard L, Alizon M, Turner JD, Hoxie JA, Peiper S, Neil JC, Hosie MJ. The second extracellular loop of CXCR4 determines its function as a receptor for feline immunodeficiency virus. Journal of Virology. 72: 6475-81. PMID 9658090 DOI: 10.1128/Jvi.72.8.6475-6481.1998  0.36
1997 Peiper SC, Lu ZH, Zhang TY, Wang ZX. [5] Chimeric chemokine receptors for analysis of structure-function relationships Methods in Enzymology. 288: 56-70. PMID 9356987 DOI: 10.1016/S0076-6879(97)88007-X  0.496
1997 Wang ZX, Cen YH, Guo HH, Du JG, Peiper SC. Expression of chemokine receptors in insect cells using baculovirus vectors. Methods in Enzymology. 288: 38-55. PMID 9356986 DOI: 10.1016/S0076-6879(97)88006-8  0.323
1997 Bron R, Klasse PJ, Wilkinson D, Clapham PR, Pelchen-Matthews A, Power C, Wells TNC, Kim J, Peiper SC, Hoxie JA, Marsh M. Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by a human immunodeficiency virus type 2 envelope protein Journal of Virology. 71: 8405-8415. PMID 9343197 DOI: 10.1128/Jvi.71.11.8405-8415.1997  0.356
1997 Doranz BJ, Lu ZH, Rucker J, Zhang TY, Sharron M, Cen YH, Wang ZX, Guo HH, Du JG, Accavitti MA, Doms RW, Peiper SC. Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1. Journal of Virology. 71: 6305-14. PMID 9261347 DOI: 10.1128/Jvi.71.9.6305-6314.1997  0.354
1997 Lu Z, Berson JF, Chen Y, Turner JD, Zhang T, Sharron M, Jenks MH, Wang Z, Kim J, Rucker J, Hoxie JA, Peiper SC, Doms RW. Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains. Proceedings of the National Academy of Sciences of the United States of America. 94: 6426-31. PMID 9177234 DOI: 10.1073/Pnas.94.12.6426  0.328
1997 Hadley TJ, Peiper SC. From malaria to chemokine receptor: The emerging physiologic role of the Duffy blood group antigen Blood. 89: 3077-3091. PMID 9129009 DOI: 10.1182/Blood.V89.9.3077  0.322
1997 Edinger AL, Amedee A, Miller K, Doranz BJ, Endres M, Sharron M, Samson M, Lu ZH, Clements JE, Murphey-Corb M, Peiper SC, Parmentier M, Broder CC, Doms RW. Differential utilization of CCR5 by macrophage and T cell tropic simian immunodeficiency virus strains. Proceedings of the National Academy of Sciences of the United States of America. 94: 4005-10. PMID 9108095 DOI: 10.1073/Pnas.94.8.4005  0.32
1997 Rana S, Besson G, Cook DG, Rucker J, Smyth RJ, Yi Y, Turner JD, Guo HH, Du JG, Peiper SC, Lavi E, Samson M, Libert F, Liesnard C, Vassart G, et al. Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation. Journal of Virology. 71: 3219-27. PMID 9060685 DOI: 10.1128/Jvi.71.4.3219-3227.1997  0.302
1997 Hesselgesser J, Halks-Miller M, DelVecchio V, Peiper SC, Hoxie J, Kolson DL, Taub D, Horuk R. CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons. Current Biology : Cb. 7: 112-21. PMID 9024623 DOI: 10.1016/S0960-9822(06)00055-8  0.338
1996 Doranz BJ, Rucker J, Yi Y, Smyth RJ, Samson M, Peiper SC, Parmentier M, Collman RG, Doms RW. A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell. 85: 1149-58. PMID 8674120 DOI: 10.1016/S0092-8674(00)81314-8  0.309
1996 Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M, Di Marzio P, Marmon S, Sutton RE, Mark Hill C, Davis CB, Peiper SC, Schall TJ, Littman DR, Landau NR. Identification of a major co-receptor for primary isolates of HIV-1 Nature. 381: 661-666. PMID 8649511 DOI: 10.1038/381661A0  0.308
1996 Horuk R, Martin A, Hesselgesser J, Hadley T, Lu ZH, Wang ZX, Peiper SC. The Duffy antigen receptor for chemokines: Structural analysis and expression in the brain Journal of Leukocyte Biology. 59: 29-38. PMID 8558064 DOI: 10.1002/Jlb.59.1.29  0.347
1995 Peiper SC, Wang ZX, Neote K, Martin AW, Showell HJ, Conklyn MJ, Ogborne K, Hadley TJ, Lu ZH, Hesselgesser J, Horuk R. The Duffy antigen/receptor for chemokines (DARC) is expressed in endothelial cells of Duffy negative individuals who lack the erythrocyte receptor Journal of Experimental Medicine. 181: 1311-1317. PMID 7699323 DOI: 10.1084/Jem.181.4.1311  0.356
1995 Horuk R, Peiper SC. Review biologicals & immunologicals; the chemokine receptor family Expert Opinion On Therapeutic Patents. 5: 1185-1200. DOI: 10.1517/13543776.5.11.1185  0.355
1994 Hadley TJ, Lu ZH, Wasniowska K, Martin AW, Peiper SC, Hesselgesser J, Horuk R. Postcapillary venule endothelial cells in kidney express a multispecific chemokine receptor that is structurally and functionally identical to the erythroid isoform, which is the Duffy blood group antigen Journal of Clinical Investigation. 94: 985-991. PMID 8083383 DOI: 10.1172/Jci117465  0.318
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