| Year |
Citation |
Score |
| 2023 |
Bennett A, Gargas J, Kansol A, Lewis J, Hsi J, Hull J, Mietzsch M, Tartaglia L, Muzyczka N, Bhattacharya N, Chipman P, Agbandje-McKenna M, McKenna R. Structural and Biophysical Analysis of Adeno-Associated Virus Serotype 2 Capsid Assembly Variants. Journal of Virology. e0177222. PMID 37310260 DOI: 10.1128/jvi.01772-22 |
0.346 |
|
| 2019 |
Gorbatyuk OS, Warrington KH, Gorbatyuk MS, Zolotukhin I, Lewin AS, Muzyczka N. Biodistribution of Adeno-Associated Virus Type 2 with Mutations in the Capsid that Contribute to Heparan Sulfate Proteoglycan Binding. Virus Research. 197771. PMID 31577935 DOI: 10.1016/J.Virusres.2019.197771 |
0.359 |
|
| 2018 |
Mendez-Gomez HR, Singh J, Meyers C, Chen W, Gorbatyuk OS, Muzyczka N. The lipase activity of phospholipase D2 is responsible for nigral neurodegeneration in a rat model of Parkinson's disease. Neuroscience. PMID 29526688 DOI: 10.1016/J.Neuroscience.2018.02.047 |
0.338 |
|
| 2017 |
Berns KI, Muzyczka N. AAV: AN OVERVIEW OF UNANSWERED QUESTIONS. Human Gene Therapy. PMID 28335618 DOI: 10.1089/Hum.2017.048 |
0.305 |
|
| 2016 |
Drouin LM, Lins B, Janssen M, Bennett A, Chipman P, McKenna R, Chen W, Muzyczka N, Cardone G, Baker TS, Agbandje-McKenna M. Cryo-electron microscopy reconstruction and stability studies of Wild-Type and R432A Variant of AAV2 Reveals Capsid Structural Stability is a Major Factor in Genome Packaging. Journal of Virology. PMID 27440903 DOI: 10.1128/Jvi.00575-16 |
0.384 |
|
| 2016 |
Aydemir F, Salganik M, Resztak J, Singh J, Bennett A, Agbandje-McKenna M, Muzyczka N. Mutants at the 2-fold interface of AAV2 structural proteins suggest a role in viral transcription for AAV capsids. Journal of Virology. PMID 27252527 DOI: 10.1128/Jvi.00493-16 |
0.786 |
|
| 2016 |
Zhang D, Li J, Feng Y, Snowden A, Aslanidi G, Muzyczka N, Srivastava A, Ling C, Ling C. 95. Incorporation of AAV Serotype 2 Viral Protein 2 into Other AAV Serotype Capsids Molecular Therapy. 24: S41-S42. DOI: 10.1016/S1525-0016(16)32904-5 |
0.459 |
|
| 2015 |
Ling C, Wang Y, Lu Y, Wang L, Jayandharan GR, Aslanidi GV, Li B, Cheng B, Ma W, Lentz T, Ling C, Xiao X, Samulski RJ, Muzyczka N, Srivastava A. The Adeno-Associated Virus Genome Packaging Puzzle. Journal of Molecular and Genetic Medicine : An International Journal of Biomedical Research. 9. PMID 26949410 DOI: 10.4172/1747-0862.1000175 |
0.465 |
|
| 2015 |
Berns KI, Byrne BJ, Flotte TR, Gao G, Hauswirth WW, Herzog RW, Muzyczka N, VandenDriessche T, Xiao X, Zolotukhin S, Srivastava A. Adeno-Associated Virus Type 2 and Hepatocellular Carcinoma? Human Gene Therapy. 26: 779-81. PMID 26690810 DOI: 10.1089/Hum.2015.29014.Kib |
0.311 |
|
| 2015 |
Tseng YS, Gurda BL, Chipman P, McKenna R, Afione S, Chiorini JA, Muzyczka N, Olson NH, Baker TS, Kleinschmidt J, Agbandje-McKenna M. Adeno-associated virus serotype 1 (AAV1)- and AAV5-antibody complex structures reveal evolutionary commonalities in parvovirus antigenic reactivity. Journal of Virology. 89: 1794-808. PMID 25410874 DOI: 10.1128/Jvi.02710-14 |
0.374 |
|
| 2015 |
Ling C, Wang Y, Lu Y, Wang L, Jayandharan GR, Aslanidi GV, Li B, Cheng B, Ma W, Lentz T, Ling C, Xiao X, Samulski RJ, Muzyczka N, Srivastava A. Enhanced transgene expression from recombinant single-stranded D-sequence-substituted adeno-associated virus vectors in human cell lines in vitro and in murine hepatocytes in vivo. Journal of Virology. 89: 952-61. PMID 25355884 DOI: 10.1128/Jvi.02581-14 |
0.585 |
|
| 2014 |
Samulski RJ, Muzyczka N. AAV-Mediated Gene Therapy for Research and Therapeutic Purposes. Annual Review of Virology. 1: 427-51. PMID 26958729 DOI: 10.1146/Annurev-Virology-031413-085355 |
0.539 |
|
| 2014 |
Schuster BS, Kim AJ, Kays JC, Kanzawa MM, Guggino WB, Boyle MP, Rowe SM, Muzyczka N, Suk JS, Hanes J. Overcoming the cystic fibrosis sputum barrier to leading adeno-associated virus gene therapy vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1484-93. PMID 24869933 DOI: 10.1038/Mt.2014.89 |
0.325 |
|
| 2014 |
Mietzsch M, Grasse S, Zurawski C, Weger S, Bennett A, Agbandje-McKenna M, Muzyczka N, Zolotukhin S, Heilbronn R. OneBac: platform for scalable and high-titer production of adeno-associated virus serotype 1-12 vectors for gene therapy. Human Gene Therapy. 25: 212-22. PMID 24299301 DOI: 10.1089/Hum.2013.184 |
0.353 |
|
| 2014 |
Salganik M, Aydemir F, Nam HJ, McKenna R, Agbandje-McKenna M, Muzyczka N. Adeno-associated virus capsid proteins may play a role in transcription and second-strand synthesis of recombinant genomes. Journal of Virology. 88: 1071-9. PMID 24198419 DOI: 10.1128/Jvi.02093-13 |
0.784 |
|
| 2013 |
Tartaglia LJ, Bennett A, Plattner AS, Muzyczka N, Ling C, Srivastava A, Agbandje-McKenna M. Molecular cloning, overexpression, and an efficient one-step purification of α5β1 integrin. Protein Expression and Purification. 92: 21-8. PMID 23993979 DOI: 10.1016/J.Pep.2013.08.013 |
0.334 |
|
| 2013 |
Govindasamy L, DiMattia MA, Gurda BL, Halder S, McKenna R, Chiorini JA, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Structural insights into adeno-associated virus serotype 5. Journal of Virology. 87: 11187-99. PMID 23926356 DOI: 10.1128/Jvi.00867-13 |
0.424 |
|
| 2013 |
Gurda BL, DiMattia MA, Miller EB, Bennett A, McKenna R, Weichert WS, Nelson CD, Chen WJ, Muzyczka N, Olson NH, Sinkovits RS, Chiorini JA, Zolotutkhin S, Kozyreva OG, Samulski RJ, et al. Capsid antibodies to different adeno-associated virus serotypes bind common regions. Journal of Virology. 87: 9111-24. PMID 23760240 DOI: 10.1128/Jvi.00622-13 |
0.547 |
|
| 2013 |
Venkatakrishnan B, Yarbrough J, Domsic J, Bennett A, Bothner B, Kozyreva OG, Samulski RJ, Muzyczka N, McKenna R, Agbandje-McKenna M. Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid trafficking. Journal of Virology. 87: 4974-84. PMID 23427155 DOI: 10.1128/Jvi.02524-12 |
0.58 |
|
| 2012 |
Salganik M, Venkatakrishnan B, Bennett A, Lins B, Yarbrough J, Muzyczka N, Agbandje-McKenna M, McKenna R. Evidence for pH-dependent protease activity in the adeno-associated virus capsid. Journal of Virology. 86: 11877-85. PMID 22915820 DOI: 10.1128/Jvi.01717-12 |
0.77 |
|
| 2012 |
DiMattia MA, Nam HJ, Van Vliet K, Mitchell M, Bennett A, Gurda BL, McKenna R, Olson NH, Sinkovits RS, Potter M, Byrne BJ, Aslanidi G, Zolotukhin S, Muzyczka N, Baker TS, et al. Structural insight into the unique properties of adeno-associated virus serotype 9. Journal of Virology. 86: 6947-58. PMID 22496238 DOI: 10.1128/Jvi.07232-11 |
0.395 |
|
| 2012 |
Gorbatyuk MS, Shabashvili A, Chen W, Meyers C, Sullivan LF, Salganik M, Lin JH, Lewin AS, Muzyczka N, Gorbatyuk OS. Glucose regulated protein 78 diminishes α-synuclein neurotoxicity in a rat model of Parkinson disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1327-37. PMID 22434142 DOI: 10.1038/Mt.2012.28 |
0.751 |
|
| 2011 |
Nam HJ, Gurda BL, McKenna R, Potter M, Byrne B, Salganik M, Muzyczka N, Agbandje-McKenna M. Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. Journal of Virology. 85: 11791-9. PMID 21900159 DOI: 10.1128/Jvi.05305-11 |
0.778 |
|
| 2010 |
Choi YK, Nash K, Byrne BJ, Muzyczka N, Song S. The effect of DNA-dependent protein kinase on adeno-associated virus replication. Plos One. 5: e15073. PMID 21188139 DOI: 10.1371/Journal.Pone.0015073 |
0.371 |
|
| 2010 |
Ojano-Dirain C, Glushakova LG, Zhong L, Zolotukhin S, Muzyczka N, Srivastava A, Stacpoole PW. An animal model of PDH deficiency using AAV8-siRNA vector-mediated knockdown of pyruvate dehydrogenase E1α. Molecular Genetics and Metabolism. 101: 183-91. PMID 20685142 DOI: 10.1016/J.Ymgme.2010.07.008 |
0.369 |
|
| 2010 |
Gorbatyuk OS, Li S, Nguyen FN, Manfredsson FP, Kondrikova G, Sullivan LF, Meyers C, Chen W, Mandel RJ, Muzyczka N. α-Synuclein expression in rat substantia nigra suppresses phospholipase D2 toxicity and nigral neurodegeneration. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1758-68. PMID 20664530 DOI: 10.1038/Mt.2010.137 |
0.333 |
|
| 2010 |
Gorbatyuk MS, Knox T, LaVail MM, Gorbatyuk OS, Noorwez SM, Hauswirth WW, Lin JH, Muzyczka N, Lewin AS. Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78. Proceedings of the National Academy of Sciences of the United States of America. 107: 5961-6. PMID 20231467 DOI: 10.1073/Pnas.0911991107 |
0.344 |
|
| 2010 |
Ojano-Dirain C, Glushakova LG, Muzyczka N, Srivastava A, Stacpoole PW. 10 Adeno-associated virus-mediated knockdown of pyruvate dehydrogenase E1α in specific regions of the rat brain Mitochondrion. 10: 202-203. DOI: 10.1016/J.Mito.2009.12.010 |
0.336 |
|
| 2009 |
Manfredsson FP, Burger C, Rising AC, Zuobi-Hasona K, Sullivan LF, Lewin AS, Huang J, Piercefield E, Muzyczka N, Mandel RJ. Tight Long-term dynamic doxycycline responsive nigrostriatal GDNF using a single rAAV vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1857-67. PMID 19707186 DOI: 10.1038/Mt.2009.196 |
0.342 |
|
| 2009 |
Mitchell M, Nam HJ, Carter A, McCall A, Rence C, Bennett A, Gurda B, McKenna R, Porter M, Sakai Y, Byrne BJ, Muzyczka N, Aslanidi G, Zolotukhin S, Agbandje-McKenna M. Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 9. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 715-8. PMID 19574648 DOI: 10.1107/S1744309109021460 |
0.33 |
|
| 2009 |
Peden CS, Manfredsson FP, Reimsnider SK, Poirier AE, Burger C, Muzyczka N, Mandel RJ. Striatal readministration of rAAV vectors reveals an immune response against AAV2 capsids that can be circumvented. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 524-37. PMID 19142181 DOI: 10.1038/Mt.2008.284 |
0.351 |
|
| 2009 |
Levy HC, Bowman VD, Govindasamy L, McKenna R, Nash K, Warrington K, Chen W, Muzyczka N, Yan X, Baker TS, Agbandje-McKenna M. Heparin binding induces conformational changes in Adeno-associated virus serotype 2. Journal of Structural Biology. 165: 146-56. PMID 19121398 DOI: 10.1016/J.Jsb.2008.12.002 |
0.395 |
|
| 2009 |
Nash K, Chen W, Salganik M, Muzyczka N. Identification of cellular proteins that interact with the adeno-associated virus rep protein. Journal of Virology. 83: 454-69. PMID 18971280 DOI: 10.1128/Jvi.01939-08 |
0.778 |
|
| 2008 |
Carty NC, Nash K, Lee D, Mercer M, Gottschall PE, Meyers C, Muzyczka N, Gordon MN, Morgan D. Adeno-associated Viral (AAV) Serotype 5 Vector Mediated Gene Delivery of Endothelin-converting Enzyme Reduces Aβ Deposits in APP + PS1 Transgenic Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1580-1586. PMID 28189012 DOI: 10.1038/Mt.2008.148 |
0.321 |
|
| 2008 |
Zhong L, Li B, Jayandharan G, Mah CS, Govindasamy L, Agbandje-McKenna M, Herzog RW, Weigel-Van Aken KA, Hobbs JA, Zolotukhin S, Muzyczka N, Srivastava A. Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression. Virology. 381: 194-202. PMID 18834608 DOI: 10.1016/J.Virol.2008.08.027 |
0.402 |
|
| 2008 |
Zhong L, Li B, Mah CS, Govindasamy L, Agbandje-McKenna M, Cooper M, Herzog RW, Zolotukhin I, Warrington KH, Weigel-Van Aken KA, Hobbs JA, Zolotukhin S, Muzyczka N, Srivastava A. Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses. Proceedings of the National Academy of Sciences of the United States of America. 105: 7827-32. PMID 18511559 DOI: 10.1073/Pnas.0802866105 |
0.395 |
|
| 2008 |
Nash K, Chen W, Muzyczka N. Complete in vitro reconstitution of adeno-associated virus DNA replication requires the minichromosome maintenance complex proteins. Journal of Virology. 82: 1458-64. PMID 18057257 DOI: 10.1128/Jvi.01968-07 |
0.424 |
|
| 2008 |
Snyder R, Potter M, Phillipsberg G, Phillipsberg T, Petersen M, Sanders D, Fife J, Korytov I, Zolotukhin S, Muzyczka N, Francis J, Flotte T. Manufacture and Stability of the Recombinant Adeno-Associated Virus Serotype 2 Vector Reference Standard Bioprocessing Journal. 7: 8-14. DOI: 10.12665/J72.Snyder |
0.385 |
|
| 2007 |
Quesada O, Gurda B, Govindasamy L, McKenna R, Kohlbrenner E, Aslanidi G, Zolotukhin S, Muzyczka N, Agbandje-McKenna M. Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 7. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 1073-6. PMID 18084098 DOI: 10.1107/S1744309107060289 |
0.329 |
|
| 2007 |
Nam HJ, Lane MD, Padron E, Gurda B, McKenna R, Kohlbrenner E, Aslanidi G, Byrne B, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Structure of adeno-associated virus serotype 8, a gene therapy vector. Journal of Virology. 81: 12260-71. PMID 17728238 DOI: 10.1128/Jvi.01304-07 |
0.427 |
|
| 2007 |
Reimsnider S, Manfredsson FP, Muzyczka N, Mandel RJ. Time course of transgene expression after intrastriatal pseudotyped rAAV2/1, rAAV2/2, rAAV2/5, and rAAV2/8 transduction in the rat. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1504-11. PMID 17565350 DOI: 10.1038/Sj.Mt.6300227 |
0.343 |
|
| 2007 |
Nash K, Chen W, McDonald WF, Zhou X, Muzyczka N. Purification of host cell enzymes involved in adeno-associated virus DNA replication. Journal of Virology. 81: 5777-87. PMID 17360744 DOI: 10.1128/Jvi.02651-06 |
0.383 |
|
| 2006 |
Miller EB, Gurda-Whitaker B, Govindasamy L, McKenna R, Zolotukhin S, Muzyczka N, Agbandje-McKenna M. Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 1271-4. PMID 17142915 DOI: 10.1107/S1744309106048184 |
0.369 |
|
| 2006 |
Brantly ML, Spencer LT, Humphries M, Conlon TJ, Spencer CT, Poirier A, Garlington W, Baker D, Song S, Berns KI, Muzyczka N, Snyder RO, Byrne BJ, Flotte TR. Phase I trial of intramuscular injection of a recombinant adeno-associated virus serotype 2 alphal-antitrypsin (AAT) vector in AAT-deficient adults. Human Gene Therapy. 17: 1177-86. PMID 17115945 DOI: 10.1089/Hum.2006.17.1177 |
0.36 |
|
| 2006 |
Govindasamy L, Padron E, McKenna R, Muzyczka N, Kaludov N, Chiorini JA, Agbandje-McKenna M. Structurally mapping the diverse phenotype of adeno-associated virus serotype 4. Journal of Virology. 80: 11556-70. PMID 16971437 DOI: 10.1128/Jvi.01536-06 |
0.426 |
|
| 2005 |
DiMattia M, Govindasamy L, Levy HC, Gurda-Whitaker B, Kalina A, Kohlbrenner E, Chiorini JA, McKenna R, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Production, purification, crystallization and preliminary X-ray structural studies of adeno-associated virus serotype 5. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 917-21. PMID 16511195 DOI: 10.1107/S1744309105028514 |
0.35 |
|
| 2005 |
Lane MD, Nam HJ, Padron E, Gurda-Whitaker B, Kohlbrenner E, Aslanidi G, Byrne B, McKenna R, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Production, purification, crystallization and preliminary X-ray analysis of adeno-associated virus serotype 8. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 558-61. PMID 16511095 DOI: 10.1107/S1744309105014132 |
0.364 |
|
| 2005 |
Kohlbrenner E, Aslanidi G, Nash K, Shklyaev S, Campbell-Thompson M, Byrne BJ, Snyder RO, Muzyczka N, Warrington KH, Zolotukhin S. Successful production of pseudotyped rAAV vectors using a modified baculovirus expression system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 1217-25. PMID 16213797 DOI: 10.1016/J.Ymthe.2005.08.018 |
0.372 |
|
| 2005 |
Gigout L, Rebollo P, Clement N, Warrington KH, Muzyczka N, Linden RM, Weber T. Altering AAV tropism with mosaic viral capsids. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 856-65. PMID 15922956 DOI: 10.1016/J.Ymthe.2005.03.005 |
0.423 |
|
| 2005 |
Muzyczka N, Warrington KH. Custom adeno-associated virus capsids: the next generation of recombinant vectors with novel tropism. Human Gene Therapy. 16: 408-16. PMID 15871672 DOI: 10.1089/Hum.2005.16.408 |
0.4 |
|
| 2005 |
Padron E, Bowman V, Kaludov N, Govindasamy L, Levy H, Nick P, McKenna R, Muzyczka N, Chiorini JA, Baker TS, Agbandje-McKenna M. Structure of adeno-associated virus type 4. Journal of Virology. 79: 5047-58. PMID 15795290 DOI: 10.1128/Jvi.79.8.5047-5058.2005 |
0.409 |
|
| 2005 |
Eslamboli A, Georgievska B, Ridley RM, Baker HF, Muzyczka N, Burger C, Mandel RJ, Annett L, Kirik D. Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 769-77. PMID 15673656 DOI: 10.1523/Jneurosci.4421-04.2005 |
0.338 |
|
| 2005 |
Reimsnider SK, Manfredsson F, Muzyczka N, Mandel RJ. 1082. Transduction Comparison of AAV Serotype Vectors in the Central Nervous System Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.629 |
0.386 |
|
| 2005 |
Kohlbrenner E, Aslanidi G, Nash K, Shklayev S, Campbell-Thompson M, Byrne BJ, Snyder RO, Muzyczka N, Warrington KH, Zolotukhin S. 400. Successful Production of Pseudotyped Mosaic rAAV Vectors Using a Modified Baculovirus Expression System Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.403 |
0.35 |
|
| 2005 |
Manfredsson FP, Lewin AS, Muzyczka N, Burger C, Mandel RJ. 59. rAAV-Mediated Nigral Parkin Over-Expression Is Neuroprotective in the 6-OHDA Rat Model of Parkinson's Disease Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.087 |
0.362 |
|
| 2004 |
Burger C, Gorbatyuk OS, Velardo MJ, Peden CS, Williams P, Zolotukhin S, Reier PJ, Mandel RJ, Muzyczka N. Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 302-17. PMID 15294177 DOI: 10.1016/J.Ymthe.2004.05.024 |
0.367 |
|
| 2004 |
Warrington KH, Gorbatyuk OS, Harrison JK, Opie SR, Zolotukhin S, Muzyczka N. Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus. Journal of Virology. 78: 6595-609. PMID 15163751 DOI: 10.1128/Jvi.78.12.6595-6609.2004 |
0.783 |
|
| 2004 |
Peden CS, Burger C, Muzyczka N, Mandel RJ. Circulating anti-wild-type adeno-associated virus type 2 (AAV2) antibodies inhibit recombinant AAV2 (rAAV2)-mediated, but not rAAV5-mediated, gene transfer in the brain. Journal of Virology. 78: 6344-59. PMID 15163728 DOI: 10.1128/Jvi.78.12.6344-6359.2004 |
0.356 |
|
| 2004 |
Lou HJ, Brister JR, Li JJ, Chen W, Muzyczka N, Tan W. Adeno-associated virus Rep78/Rep68 promotes localized melting of the rep binding element in the absence of adenosine triphosphate. Chembiochem : a European Journal of Chemical Biology. 5: 324-32. PMID 14997524 DOI: 10.1002/Cbic.200300737 |
0.363 |
|
| 2004 |
Kohlbrenner E, Aslanidi G, Knop DR, Gorbatyuk O, Nash K, Mandel RJ, Muzyczka N, Burns BJ, Snyder RO, Zolotukhin S. 420. Adaptation of Baculovirus System for Large-Scale Production of rAAV Vector Serotypes Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.340 |
0.334 |
|
| 2003 |
Eslamboli A, Cummings RM, Ridley RM, Baker HF, Muzyczka N, Burger C, Mandel RJ, Kirik D, Annett LE. Recombinant adeno-associated viral vector (rAAV) delivery of GDNF provides protection against 6-OHDA lesion in the common marmoset monkey (Callithrix jacchus). Experimental Neurology. 184: 536-48. PMID 14637123 DOI: 10.1016/J.Expneurol.2003.08.007 |
0.305 |
|
| 2003 |
Li Z, Brister JR, Im DS, Muzyczka N. Characterization of the adenoassociated virus Rep protein complex formed on the viral origin of DNA replication. Virology. 313: 364-76. PMID 12954205 DOI: 10.1016/S0042-6822(03)00340-4 |
0.394 |
|
| 2003 |
Loiler SA, Conlon TJ, Song S, Tang Q, Warrington KH, Agarwal A, Kapturczak M, Li C, Ricordi C, Atkinson MA, Muzyczka N, Flotte TR. Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver. Gene Therapy. 10: 1551-8. PMID 12907946 DOI: 10.1038/Sj.Gt.3302046 |
0.335 |
|
| 2003 |
Opie SR, Warrington KH, Agbandje-McKenna M, Zolotukhin S, Muzyczka N. Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding. Journal of Virology. 77: 6995-7006. PMID 12768018 DOI: 10.1128/Jvi.77.12.6995-7006.2003 |
0.786 |
|
| 2003 |
Matalon R, Surendran S, Rady PL, Quast MJ, Campbell GA, Matalon KM, Tyring SK, Wei J, Peden CS, Ezell EL, Muzyczka N, Mandel RJ. Adeno-associated virus-mediated aspartoacylase gene transfer to the brain of knockout mouse for canavan disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 580-7. PMID 12718900 DOI: 10.1016/S1525-0016(03)00066-2 |
0.3 |
|
| 2002 |
Zolotukhin S, Potter M, Zolotukhin I, Sakai Y, Loiler S, Fraites TJ, Chiodo VA, Phillipsberg T, Muzyczka N, Hauswirth WW, Flotte TR, Byrne BJ, Snyder RO. Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors. Methods (San Diego, Calif.). 28: 158-67. PMID 12413414 DOI: 10.1016/S1046-2023(02)00220-7 |
0.389 |
|
| 2002 |
Xiao W, Warrington KH, Hearing P, Hughes J, Muzyczka N. Adenovirus-facilitated nuclear translocation of adeno-associated virus type 2. Journal of Virology. 76: 11505-17. PMID 12388712 DOI: 10.1128/Jvi.76.22.11505-11517.2002 |
0.385 |
|
| 2002 |
Lackner DF, Muzyczka N. Studies of the mechanism of transactivation of the adeno-associated virus p19 promoter by Rep protein. Journal of Virology. 76: 8225-35. PMID 12134028 DOI: 10.1128/Jvi.76.16.8225-8235.2002 |
0.729 |
|
| 2002 |
Shi W, Teschendorf C, Muzyczka N, Siemann DW. Adeno-associated virus-mediated gene transfer of endostatin inhibits angiogenesis and tumor growth in vivo. Cancer Gene Therapy. 9: 513-21. PMID 12032662 DOI: 10.1038/Sj.Cgt.7700463 |
0.328 |
|
| 2002 |
Andsberg G, Kokaia Z, Klein RL, Muzyczka N, Lindvall O, Mandel RJ. Neuropathological and behavioral consequences of adeno-associated viral vector-mediated continuous intrastriatal neurotrophin delivery in a focal ischemia model in rats. Neurobiology of Disease. 9: 187-204. PMID 11895371 DOI: 10.1006/Nbdi.2001.0456 |
0.314 |
|
| 2002 |
Potter M, Chesnut K, Muzyczka N, Flotte T, Zolotukhin S. Streamlined large-scale production of recombinant adeno-associated virus (rAAV) vectors. Methods in Enzymology. 346: 413-30. PMID 11883083 DOI: 10.1016/S0076-6879(02)46069-7 |
0.354 |
|
| 2001 |
Dhillon H, Kalra SP, Prima V, Zolotukhin S, Scarpace PJ, Moldawer LL, Muzyczka N, Kalra PS. Central leptin gene therapy suppresses body weight gain, adiposity and serum insulin without affecting food consumption in normal rats: a long-term study. Regulatory Peptides. 99: 69-77. PMID 11384767 DOI: 10.1016/S0167-0115(01)00237-3 |
0.312 |
|
| 2000 |
Klein RL, Mandel RJ, Muzyczka N. Adeno-associated virus vector-mediated gene transfer to somatic cells in the central nervous system. Advances in Virus Research. 55: 507-28. PMID 11050954 DOI: 10.1016/S0065-3527(00)55015-5 |
0.404 |
|
| 2000 |
Wu P, Xiao W, Conlon T, Hughes J, Agbandje-McKenna M, Ferkol T, Flotte T, Muzyczka N. Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism. Journal of Virology. 74: 8635-47. PMID 10954565 DOI: 10.1128/Jvi.74.18.8635-8647.2000 |
0.359 |
|
| 2000 |
Brister JR, Muzyczka N. Mechanism of Rep-mediated adeno-associated virus origin nicking. Journal of Virology. 74: 7762-71. PMID 10933682 DOI: 10.1128/Jvi.74.17.7762-7771.2000 |
0.434 |
|
| 2000 |
Hauswirth WW, Lewin AS, Zolotukhin S, Muzyczka N. Production and purification of recombinant adeno-associated virus. Methods in Enzymology. 316: 743-61. PMID 10800712 DOI: 10.1016/S0076-6879(00)16760-6 |
0.416 |
|
| 2000 |
Gavin DK, Young SM, Xiao W, Temple B, Abernathy CR, Pereira DJ, Muzyczka N, Samulski RJ. Charge-to-Alanine Mutagenesis of the Adeno-Associated Virus Type 2 Rep78/68 Proteins Yields Temperature-Sensitive and Magnesium-Dependent Variants Journal of Virology. 74: 591-591. DOI: 10.1128/Jvi.74.1.591-591.2000 |
0.621 |
|
| 1999 |
Klein RL, Lewis MH, Muzyczka N, Meyer EM. Prevention of 6-hydroxydopamine-induced rotational behavior by BDNF somatic gene transfer. Brain Research. 847: 314-20. PMID 10575102 DOI: 10.1016/S0006-8993(99)02116-2 |
0.343 |
|
| 1999 |
Gavin DK, Young SM, Xiao W, Temple B, Abernathy CR, Pereira DJ, Muzyczka N, Samulski RJ. Charge-to-alanine mutagenesis of the adeno-associated virus type 2 Rep78/68 proteins yields temperature-sensitive and magnesium-dependent variants. Journal of Virology. 73: 9433-45. PMID 10516052 |
0.581 |
|
| 1999 |
Brister JR, Muzyczka N. Rep-mediated nicking of the adeno-associated virus origin requires two biochemical activities, DNA helicase activity and transesterification. Journal of Virology. 73: 9325-36. PMID 10516041 DOI: 10.1128/Jvi.73.11.9325-9336.1999 |
0.386 |
|
| 1999 |
Conway JE, Rhys CM, Zolotukhin I, Zolotukhin S, Muzyczka N, Hayward GS, Byrne BJ. High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 Rep and Cap. Gene Therapy. 6: 986-93. PMID 10455400 DOI: 10.1038/Sj.Gt.3300937 |
0.412 |
|
| 1999 |
Zolotukhin S, Byrne BJ, Mason E, Zolotukhin I, Potter M, Chesnut K, Summerford C, Samulski RJ, Muzyczka N. Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield. Gene Therapy. 6: 973-85. PMID 10455399 DOI: 10.1038/Sj.Gt.3300938 |
0.517 |
|
| 1999 |
Guy J, Qi X, Muzyczka N, Hauswirth WW. Reporter expression persists 1 year after adeno-associated virus-mediated gene transfer to the optic nerve. Archives of Ophthalmology (Chicago, Ill. : 1960). 117: 929-37. PMID 10408459 DOI: 10.1001/Archopht.117.7.929 |
0.315 |
|
| 1999 |
Klein RL, McNamara RK, King MA, Lenox RH, Muzyczka N, Meyer EM. Generation of aberrant sprouting in the adult rat brain by GAP-43 somatic gene transfer. Brain Research. 832: 136-44. PMID 10375659 DOI: 10.1016/S0006-8993(99)01482-1 |
0.331 |
|
| 1999 |
Klein RL, Muir D, King MA, Peel AL, Zolotukhin S, Möller JC, Krüttgen A, Heymach JV, Muzyczka N, Meyer EM. Long-term actions of vector-derived nerve growth factor or brain-derived neurotrophic factor on choline acetyltransferase and Trk receptor levels in the adult rat basal forebrain. Neuroscience. 90: 815-21. PMID 10218782 DOI: 10.1016/S0306-4522(98)00537-5 |
0.316 |
|
| 1999 |
Daly TM, Okuyama T, Vogler C, Haskins ME, Muzyczka N, Sands MS. Neonatal intramuscular injection with recombinant adeno-associated virus results in prolonged beta-glucuronidase expression in situ and correction of liver pathology in mucopolysaccharidosis type VII mice. Human Gene Therapy. 10: 85-94. PMID 10022533 DOI: 10.1089/10430349950019219 |
0.346 |
|
| 1999 |
Zhou X, Zolotukhin I, Im DS, Muzyczka N. Biochemical characterization of adeno-associated virus rep68 DNA helicase and ATPase activities. Journal of Virology. 73: 1580-90. PMID 9882364 DOI: 10.1128/Jvi.73.2.1580-1590.1999 |
0.356 |
|
| 1999 |
Samulski RJ, Sally M, Muzyczka N. 7 Adeno-associated Viral Vectors Cold Spring Harbor Monograph Archive. 36: 131-172. DOI: 10.1101/087969528.36.131 |
0.578 |
|
| 1998 |
Warrington KH, Teschendorf C, Cao L, Muzyczka N, Siemann DW. Developing VDEPT for DT-diaphorase (NQO1) using an AAV vector plasmid. International Journal of Radiation Oncology, Biology, Physics. 42: 909-12. PMID 9845120 DOI: 10.1016/S0360-3016(98)00357-5 |
0.372 |
|
| 1998 |
Song S, Morgan M, Ellis T, Poirier A, Chesnut K, Wang J, Brantly M, Muzyczka N, Byrne BJ, Atkinson M, Flotte TR. Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectors. Proceedings of the National Academy of Sciences of the United States of America. 95: 14384-8. PMID 9826709 DOI: 10.1073/Pnas.95.24.14384 |
0.355 |
|
| 1998 |
Lalwani A, Walsh B, Reilly P, Carvalho G, Zolotukhin S, Muzyczka N, Mhatre A. Long-term in vivo cochlear transgene expression mediated by recombinant adeno-associated virus. Gene Therapy. 5: 277-81. PMID 9578849 DOI: 10.1038/Sj.Gt.3300573 |
0.335 |
|
| 1998 |
Klein RL, Meyer EM, Peel AL, Zolotukhin S, Meyers C, Muzyczka N, King MA. Neuron-specific transduction in the rat septohippocampal or nigrostriatal pathway by recombinant adeno-associated virus vectors. Experimental Neurology. 150: 183-94. PMID 9527887 DOI: 10.1006/Exnr.1997.6736 |
0.405 |
|
| 1998 |
Ni TH, McDonald WF, Zolotukhin I, Melendy T, Waga S, Stillman B, Muzyczka N. Cellular proteins required for adeno-associated virus DNA replication in the absence of adenovirus coinfection. Journal of Virology. 72: 2777-87. PMID 9525597 DOI: 10.1128/Jvi.72.4.2777-2787.1998 |
0.397 |
|
| 1997 |
Lalwani AK, Han JJ, Walsh BJ, Zolotukhin S, Muzyczka N, Mhatre AN. Green fluorescent protein as a reporter for gene transfer studies in the cochlea. Hearing Research. 114: 139-47. PMID 9447928 DOI: 10.1016/S0378-5955(97)00151-2 |
0.343 |
|
| 1997 |
Conway JE, Zolotukhin S, Muzyczka N, Hayward GS, Byrne BJ. Recombinant adeno-associated virus type 2 replication and packaging is entirely supported by a herpes simplex virus type 1 amplicon expressing Rep and Cap. Journal of Virology. 71: 8780-9. PMID 9343238 DOI: 10.1128/Jvi.71.11.8780-8789.1997 |
0.462 |
|
| 1997 |
Peel AL, Zolotukhin S, Schrimsher GW, Muzyczka N, Reier PJ. Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters Gene Therapy. 4: 16-24. PMID 9068791 DOI: 10.1038/Sj.Gt.3300358 |
0.325 |
|
| 1996 |
Zolotukhin S, Potter M, Hauswirth WW, Guy J, Muzyczka N. A "Humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells Journal of Virology. 70: 4646-4654. PMID 8676491 DOI: 10.1128/Jvi.70.7.4646-4654.1996 |
0.383 |
|
| 1993 |
Snyder RO, Im DS, Ni T, Xiao X, Samulski RJ, Muzyczka N. Features of the adeno-associated virus origin involved in substrate recognition by the viral rep protein Journal of Virology. 67: 6096-6104. PMID 8396670 DOI: 10.1128/Jvi.67.10.6096-6104.1993 |
0.523 |
|
| 1993 |
Snyder RO, Im DS, Ni T, Xiao X, Samulski RJ, Muzyczka N. Features of the adeno-associated virus origin involved in substrate recognition by the viral Rep protein. Journal of Virology. 67: 6096-6104. DOI: 10.1128/jvi.67.10.6096-6104.1993 |
0.531 |
|
| 1992 |
Mccarty DM, Ni TH, Muzyczka N. Analysis of mutations in adeno-associated virus rep protein in vivo and in vitro Journal of Virology. 66: 4050-4057. PMID 1318396 |
0.321 |
|
| 1990 |
Snyder RO, Im DS, Muzyczka N. Evidence for covalent attachment of the adeno-associated virus (AAV) Rep protein to the ends of the AAV genome Journal of Virology. 64: 6204-6213. PMID 2173787 |
0.363 |
|
| 1990 |
Im DS, Muzyczka N. The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity Cell. 61: 447-457. PMID 2159383 DOI: 10.1016/0092-8674(90)90526-K |
0.32 |
|
| 1990 |
Snyder RO, Samulski RJ, Muzyczka N. In vitro resolution of covalently joined AAV chromosome ends Cell. 60: 105-113. PMID 2153052 DOI: 10.1016/0092-8674(90)90720-Y |
0.519 |
|
| 1988 |
McLaughlin SK, Collis P, Hermonat PL, Muzyczka N. Adeno-associated virus general transduction vectors: Analysis of proviral structures Journal of Virology. 62: 1963-1973. PMID 2835501 |
0.315 |
|
| 1985 |
Rayfield M, Michaels GS, Feldmann R, Muzyczka N. Comparison of the DNA sequence and secondary structure of the herpes simplex virus L/S junction and the adeno-associated virus terminal repeat Journal of Theoretical Biology. 115: 477-494. PMID 2995732 DOI: 10.1016/S0022-5193(85)80136-3 |
0.404 |
|
| 1984 |
Muzyczka N, Samulski RJ, Hermonat P, Srivastava A, Berns KI. The genetics of adeno-associated virus. Advances in Experimental Medicine and Biology. 179: 151-61. PMID 6098150 DOI: 10.1007/978-1-4684-8730-5_15 |
0.607 |
|
| 1984 |
Hermonat PL, Muzyczka N. Use of adeno-associated virus as a mammalian DNA cloning vector: Transduction of neomycin resistance into mammalian tissue culture cells Proceedings of the National Academy of Sciences of the United States of America. 81: 6466-6470. PMID 6093102 DOI: 10.1073/Pnas.81.20.6466 |
0.428 |
|
| 1984 |
Hermonat PL, Labow MA, Wright R, Berns KI, Muzyczka N. Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants. Journal of Virology. 51: 329-39. PMID 6086948 DOI: 10.1128/Jvi.51.2.329-339.1984 |
0.441 |
|
| 1983 |
Samulski RJ, Srivastava A, Berns KI, Muzyczka N. Rescue of adeno-associated virus from recombinant plasmids: gene correction within the terminal repeats of AAV. Cell. 33: 135-43. PMID 6088052 DOI: 10.1016/0092-8674(83)90342-2 |
0.573 |
|
| 1982 |
Samulski RJ, Berns KI, Tan M, Muzyczka N. Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 2077-81. PMID 6281795 DOI: 10.1073/Pnas.79.6.2077 |
0.596 |
|
| 1982 |
Walia S, Dunn G, Rose K, Pinkerton T, Muzyczka N, Duckworth D. Restriction endonuclease mapping of the colicin Ib plasmid Mgg Molecular & General Genetics. 185: 37-42. DOI: 10.1007/Bf00333787 |
0.314 |
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