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Patrick W. Alford, Ph.D. - Publications

Affiliations: 
2007 Washington University, Saint Louis, St. Louis, MO 
Area:
Biomedical Engineering
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Cook BL, Alford PW. Continuum interpretation of mechano-adaptation in micropatterned epithelia informed by in vitro experiments. Integrative Biology : Quantitative Biosciences From Nano to Macro. 15. PMID 37539823 DOI: 10.1093/intbio/zyad009  0.305
2021 Rothermel TM, Franczek IA, Alford PW. Anisotropic Mechanics of Vascular Smooth Muscle Cells Exposed to Dynamic Loads. Journal of Biomechanical Engineering. 143. PMID 34423810 DOI: 10.1115/1.4052224  0.347
2020 Rothermel TM, Win Z, Alford PW. Large-deformation strain energy density function for vascular smooth muscle cells. Journal of Biomechanics. 111: 110005. PMID 32911443 DOI: 10.1016/J.Jbiomech.2020.110005  0.429
2018 Tabdanov ED, Puram VV, Win Z, Alamgir A, Alford PW, Provenzano PP. Bimodal sensing of guidance cues in mechanically distinct microenvironments. Nature Communications. 9: 4891. PMID 30459308 DOI: 10.1038/S41467-018-07290-Y  0.308
2018 Win Z, Buksa JM, Alford PW. Architecture-Dependent Anisotropic Hysteresis in Smooth Muscle Cells. Biophysical Journal. PMID 30348447 DOI: 10.1016/J.Bpj.2018.09.027  0.456
2018 Wheelwright M, Win Z, Mikkila JL, Amen KY, Alford PW, Metzger JM. Investigation of human iPSC-derived cardiac myocyte functional maturation by single cell traction force microscopy. Plos One. 13: e0194909. PMID 29617427 DOI: 10.1371/Journal.Pone.0194909  0.365
2017 Steucke KE, Win Z, Stemler TR, Walsh EE, Hall JL, Alford PW. Empirically Determined Vascular Smooth Muscle Cell Mechano-Adaptation Law. Journal of Biomechanical Engineering. PMID 28418526 DOI: 10.1115/1.4036454  0.43
2017 Ray A, Lee O, Win Z, Edwards RM, Alford PW, Kim DH, Provenzano PP. Anisotropic forces from spatially constrained focal adhesions mediate contact guidance directed cell migration. Nature Communications. 8: 14923. PMID 28401884 DOI: 10.1038/Ncomms14923  0.321
2017 Win Z, Buksa JM, Steucke KE, Luxton GW, Barocas VH, Alford PW. Single-cell strain energy density function measured by cellular micro-biaxial stretching. Journal of Biomechanical Engineering. PMID 28397957 DOI: 10.1115/1.4036440  0.447
2016 Witzenburg CM, Dhume RY, Shah SB, Korenczuk CE, Wagner HP, Alford PW, Barocas VH. Failure of the Porcine Ascending Aorta: Multidirectional Experiments and a Unifying Microstructural Model. Journal of Biomechanical Engineering. PMID 27893044 DOI: 10.1115/1.4035264  0.373
2016 van Loosdregt IA, Dekker S, Alford PW, Oomens CW, Loerakker S, Bouten CV. Intrinsic Cell Stress is Independent of Organization in Engineered Cell Sheets. Cardiovascular Engineering and Technology. PMID 27778297 DOI: 10.1007/S13239-016-0283-9  0.429
2016 Hald ES, Timm CD, Alford PW. Amyloid beta influences vascular smooth muscle contractility and mechano-adaptation. Journal of Biomechanical Engineering. PMID 27590124 DOI: 10.1115/1.4034560  0.373
2015 Steucke KE, Tracy PV, Hald ES, Hall JL, Alford PW. Vascular smooth muscle cell functional contractility depends on extracellular mechanical properties. Journal of Biomechanics. BMD1500461. PMID 26283412 DOI: 10.1016/J.Jbiomech.2015.07.029  0.463
2015 Hald ES, Steucke KE, Reeves JA, Win Z, Alford PW. Microfluidic Genipin Deposition Technique for Extended Culture of Micropatterned Vascular Muscular Thin Films. Journal of Visualized Experiments : Jove. e52971. PMID 26168271 DOI: 10.3791/52971  0.392
2015 Lee H, Adams WJ, Alford PW, McCain ML, Feinberg AW, Sheehy SP, Goss JA, Parker KK. Cytoskeletal prestress regulates nuclear shape and stiffness in cardiac myocytes. Experimental Biology and Medicine (Maywood, N.J.). PMID 25908635 DOI: 10.1177/1535370215583799  0.718
2015 Adhikari N, Shekar KC, Staggs R, Win Z, Steucke K, Lin YW, Wei LN, Alford P, Hall JL. Guidelines for the isolation and characterization of murine vascular smooth muscle cells. A report from the International Society of Cardiovascular Translational Research. Journal of Cardiovascular Translational Research. 8: 158-63. PMID 25788147 DOI: 10.1007/S12265-015-9616-6  0.41
2015 Alford PW. Elasticity-based targeted growth models of morphogenesis. Methods in Molecular Biology (Clifton, N.J.). 1189: 339-50. PMID 25245704 DOI: 10.1007/978-1-4939-1164-6_22  0.368
2015 Wheelwright M, Win Z, Alford PW, Metzger JM. 188. Functional Analysis of Human Induced Pluripotent Stem Cell-Derived Cardiac Myocytes Molecular Therapy. 23: S75. DOI: 10.1016/S1525-0016(16)33793-5  0.342
2015 Steucke KE, Tracy PV, Hald ES, Hall JL, Alford PW. Vascular smooth muscle cell functional contractility depends on extracellular mechanical properties Journal of Biomechanics. DOI: 10.1016/j.jbiomech.2015.07.029  0.346
2014 Win Z, Vrla GD, Steucke KE, Sevcik EN, Hald ES, Alford PW. Smooth muscle architecture within cell-dense vascular tissues influences functional contractility. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 1201-10. PMID 25363686 DOI: 10.1039/C4Ib00193A  0.477
2014 Hald ES, Steucke KE, Reeves JA, Win Z, Alford PW. Long-term vascular contractility assay using genipin-modified muscular thin films. Biofabrication. 6: 045005. PMID 25245868 DOI: 10.1088/1758-5082/6/4/045005  0.4
2014 Ye GJ, Aratyn-Schaus Y, Nesmith AP, Pasqualini FS, Alford PW, Parker KK. The contractile strength of vascular smooth muscle myocytes is shape dependent. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 152-63. PMID 24406783 DOI: 10.1039/C3Ib40230D  0.753
2014 Shah SB, Witzenburg C, Hadi MF, Wagner HP, Goodrich JM, Alford PW, Barocas VH. Prefailure and failure mechanics of the porcine ascending thoracic aorta: experiments and a multiscale model. Journal of Biomechanical Engineering. 136: 021028. PMID 24402447 DOI: 10.1115/1.4026443  0.319
2014 Hald ES, Alford PW. Smooth muscle phenotype switching in blast traumatic brain injury-induced cerebral vasospasm. Translational Stroke Research. 5: 385-93. PMID 24323722 DOI: 10.1007/S12975-013-0300-3  0.339
2012 Feinberg AW, Alford PW, Jin H, Ripplinger CM, Werdich AA, Sheehy SP, Grosberg A, Parker KK. Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture. Biomaterials. 33: 5732-41. PMID 22594976 DOI: 10.1016/J.Biomaterials.2012.04.043  0.747
2011 Balachandran K, Alford PW, Wylie-Sears J, Goss JA, Grosberg A, Bischoff J, Aikawa E, Levine RA, Parker KK. Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve. Proceedings of the National Academy of Sciences of the United States of America. 108: 19943-8. PMID 22123981 DOI: 10.1073/Pnas.1106954108  0.708
2011 Grosberg A, Alford PW, McCain ML, Parker KK. Ensembles of engineered cardiac tissues for physiological and pharmacological study: heart on a chip. Lab On a Chip. 11: 4165-73. PMID 22072288 DOI: 10.1039/C1Lc20557A  0.739
2011 Alford PW, Nesmith AP, Seywerd JN, Grosberg A, Parker KK. Vascular smooth muscle contractility depends on cell shape. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 1063-70. PMID 21993765 DOI: 10.1039/C1Ib00061F  0.659
2011 Hemphill MA, Dabiri BE, Gabriele S, Kerscher L, Franck C, Goss JA, Alford PW, Parker KK. A possible role for integrin signaling in diffuse axonal injury. Plos One. 6: e22899. PMID 21799943 DOI: 10.1371/Journal.Pone.0022899  0.495
2011 Alford PW, Dabiri BE, Goss JA, Hemphill MA, Brigham MD, Parker KK. Blast-induced phenotypic switching in cerebral vasospasm. Proceedings of the National Academy of Sciences of the United States of America. 108: 12705-10. PMID 21765001 DOI: 10.1073/Pnas.1105860108  0.574
2011 Grosberg A, Brigham MD, Goss JA, Alford PW, Parker KK. A tissue scale, in vitro, multiplex contractility assay Journal of Pharmacological and Toxicological Methods. 64: e27. DOI: 10.1016/J.Vascn.2011.03.098  0.537
2010 Alford PW, Feinberg AW, Sheehy SP, Parker KK. Biohybrid thin films for measuring contractility in engineered cardiovascular muscle. Biomaterials. 31: 3613-21. PMID 20149449 DOI: 10.1016/J.Biomaterials.2010.01.079  0.739
2009 Feinberg AW, Alford PW, Ripplinger CM, Adams WJ, Sheehy SP, Parker KK. Engineering Cardiac Contractility from the Sarcomere to Tissue-Scale Biophysical Journal. 96: 372a. DOI: 10.1016/J.Bpj.2008.12.2005  0.743
2008 Alford PW, Taber LA. Computational study of growth and remodelling in the aortic arch. Computer Methods in Biomechanics and Biomedical Engineering. 11: 525-38. PMID 18792831 DOI: 10.1080/10255840801930710  0.618
2008 Alford PW, Humphrey JD, Taber LA. Growth and remodeling in a thick-walled artery model: effects of spatial variations in wall constituents. Biomechanics and Modeling in Mechanobiology. 7: 245-62. PMID 17786493 DOI: 10.1007/S10237-007-0101-2  0.629
2005 Alford PW, Taber LA. A model of arterial growth and remodeling based on constrained mixture theory Proceedings of the 2005 Summer Bioengineering Conference. 2005: 816-817.  0.574
2004 Voronov DA, Alford PW, Xu G, Taber LA. The role of mechanical forces in dextral rotation during cardiac looping in the chick embryo. Developmental Biology. 272: 339-50. PMID 15282152 DOI: 10.1016/J.Ydbio.2004.04.033  0.627
2004 Taber LA, Voronov DA, Rémond MC, Latacha KS, Alford PW. Mechanical forces involved in cardiac C-looping Advances in Bioengineering, Bed. 197-198.  0.719
2003 Alford PW, Taber LA. Regional epicardial strain in the embryonic chick heart during the early looping stages. Journal of Biomechanics. 36: 1135-41. PMID 12831739 DOI: 10.1016/S0021-9290(03)00089-7  0.585
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