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Richard J. Isaacs, Ph.D. - Publications

Affiliations: 
2004 University of Kentucky, Lexington, KY 
Area:
Biochemistry
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2004 Isaacs RJ, Spielmann HP. A model for initial DNA lesion recognition by NER and MMR based on local conformational flexibility. Dna Repair. 3: 455-64. PMID 15162792 DOI: 10.1016/J.Dnarep.2004.01.004  0.505
2004 Isaacs RJ, Spielmann HP. Insight into G[bond]T mismatch recognition using molecular dynamics with time-averaged restraints derived from NMR spectroscopy. Journal of the American Chemical Society. 126: 583-90. PMID 14719957 DOI: 10.1021/Ja037333R  0.545
2002 Chehade KA, Kiegiel K, Isaacs RJ, Pickett JS, Bowers KE, Fierke CA, Andres DA, Spielmann HP. Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase. Journal of the American Chemical Society. 124: 8206-19. PMID 12105898 DOI: 10.1021/Ja0124717  0.565
2002 Isaacs RJ, Rayens WS, Spielmann HP. Structural differences in the NOE-derived structure of G-T mismatched DNA relative to normal DNA are correlated with differences in (13)C relaxation-based internal dynamics. Journal of Molecular Biology. 319: 191-207. PMID 12051946 DOI: 10.1016/S0022-2836(02)00265-6  0.544
2001 Micali E, Chehade KA, Isaacs RJ, Andres DA, Spielmann HP. Protein farnesyltransferase isoprenoid substrate discrimination is dependent on isoprene double bonds and branched methyl groups. Biochemistry. 40: 12254-65. PMID 11591144 DOI: 10.1021/Bi011133F  0.572
2001 Isaacs RJ, Spielmann HP. NMR evidence for mechanical coupling of phosphate B(I)-B(II) transitions with deoxyribose conformational exchange in DNA. Journal of Molecular Biology. 311: 149-60. PMID 11469864 DOI: 10.1006/Jmbi.2001.4855  0.539
2001 Isaacs RJ, Spielmann HP. Relationship of DNA structure to internal dynamics: correlation of helical parameters from NOE-based NMR solution structures of d(GCGTACGC)(2) and d(CGCTAGCG)(2) with (13)C order parameters implies conformational coupling in dinucleotide units. Journal of Molecular Biology. 307: 525-40. PMID 11254380 DOI: 10.1006/Jmbi.2001.4498  0.567
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