Rafick P. Sekaly - Publications

Affiliations: 
McGill University, Montreal, QC, Canada 
Area:
Microbiology Biology

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Desai P, Karl CE, Ying B, Liang CY, Garcia-Salum T, Santana AC, Caten FT, Urban JF, Elbashir SM, Edwards DK, Ribeiro SP, Thackray LB, Sekaly RP, Diamond MS. Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 38293221 DOI: 10.1101/2024.01.14.575588  0.349
2022 Uldrick TS, Adams SV, Fromentin R, Roche M, Fling SP, Gonçalves PH, Lurain K, Ramaswami R, Wang CJ, Gorelick RJ, Welker JL, O'Donoghue L, Choudhary H, Lifson JD, Rasmussen TA, et al. Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy. Science Translational Medicine. 14: eabl3836. PMID 35080914 DOI: 10.1126/scitranslmed.abl3836  0.335
2021 Tomalka JA, Pelletier AN, Fourati S, Latif MB, Sharma A, Furr K, Carlson K, Lifton M, Gonzalez A, Wilkinson P, Franchini G, Parks R, Letvin N, Yates N, Seaton K, ... ... Sekaly RP, et al. The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination. Nature Immunology. PMID 34556879 DOI: 10.1038/s41590-021-01026-9  0.317
2021 Pino M, Pereira Ribeiro S, Pagliuzza A, Ghneim K, Khan A, Ryan E, Harper JL, King CT, Welbourn S, Micci L, Aldrete S, Delman KA, Stuart T, Lowe M, Brenchley JM, ... Sekaly RP, et al. Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART. Plos Pathogens. 17: e1009825. PMID 34449812 DOI: 10.1371/journal.ppat.1009825  0.448
2021 Nganou-Makamdop K, Talla A, Sharma AA, Darko S, Ransier A, Laboune F, Chipman JG, Beilman GJ, Hoskuldsson T, Fourati S, Schmidt TE, Arumugam S, Lima NS, Moon D, Callisto S, ... Sekaly RP, et al. Translocated microbiome composition determines immunological outcome in treated HIV infection. Cell. PMID 34237254 DOI: 10.1016/j.cell.2021.05.023  0.36
2021 Nganou-Makamdop K, Talla A, Sharma AA, Darko S, Ransier A, Laboune F, Chipman JG, Beilman GJ, Hoskuldsson T, Fourati S, Schmidt TE, Arumugam S, Lima NS, Moon D, Callisto S, ... Sekaly RP, et al. Translocated microbiome composition determines immunological outcome in treated HIV infection. Cell. PMID 34237254 DOI: 10.1016/j.cell.2021.05.023  0.36
2020 Asokan M, Dias J, Liu C, Maximova A, Ernste K, Pegu A, McKee K, Shi W, Chen X, Almasri C, Promsote W, Ambrozak DR, Gama L, Hu J, Douek DC, ... ... Sekaly RP, et al. Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. Proceedings of the National Academy of Sciences of the United States of America. PMID 32690707 DOI: 10.1073/Pnas.2008236117  0.403
2020 Murray SM, Zhang Y, Douek DC, Sekaly RP. Myeloid Cells Enriched for a Dendritic Cell Population From People Living With HIV Have Altered Gene Expression Not Restored by Antiretroviral Therapy. Frontiers in Immunology. 11: 261. PMID 32194550 DOI: 10.3389/Fimmu.2020.00261  0.501
2020 Gorini G, Fourati S, Vaccari M, Rahman MA, Gordon SN, Brown DR, Law L, Chang J, Green R, Barrenäs F, Liyanage NPM, Doster MN, Schifanella L, Bissa M, Silva de Castro I, ... Sekaly RP, et al. Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition. Plos Pathogens. 16: e1008377. PMID 32163525 DOI: 10.1371/Journal.Ppat.1008377  0.458
2020 Van der Sluis RM, Kumar NA, Pascoe RD, Zerbato JM, Evans VA, Dantanarayana AI, Anderson JL, Sékaly RP, Fromentin R, Chomont N, Cameron PU, Lewin SR. Combination Immune Checkpoint Blockade to Reverse HIV Latency. Journal of Immunology (Baltimore, Md. : 1950). PMID 31988180 DOI: 10.4049/Jimmunol.1901191  0.464
2019 Ehrenberg PK, Shangguan S, Issac B, Alter G, Geretz A, Izumi T, Bryant C, Eller MA, Wegmann F, Apps R, Creegan M, Bolton DL, Sekaly RP, Robb ML, Gramzinski RA, et al. A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials. Science Translational Medicine. 11. PMID 31462510 DOI: 10.1126/Scitranslmed.Aaw4236  0.355
2018 Aid M, Dupuy FP, Moysi E, Moir S, Haddad EK, Estes JD, Sekaly RP, Petrovas C, Ribeiro SP. Follicular CD4 T Helper Cells As a Major HIV Reservoir Compartment: A Molecular Perspective. Frontiers in Immunology. 9: 895. PMID 29967602 DOI: 10.3389/Fimmu.2018.00895  0.495
2018 Vaccari M, Fourati S, Gordon SN, Brown DR, Bissa M, Schifanella L, Silva de Castro I, Doster MN, Galli V, Omsland M, Fujikawa D, Gorini G, Liyanage NPM, Trinh HV, McKinnon KM, ... ... Sekaly RP, et al. HIV vaccine candidate activation of hypoxia and the inflammasome in CD14 monocytes is associated with a decreased risk of SIV acquisition. Nature Medicine. PMID 29785023 DOI: 10.1038/S41591-018-0025-7  0.448
2018 Kityo C, Makamdop KN, Rothenberger M, Chipman JG, Hoskuldsson T, Beilman GJ, Grzywacz B, Mugyenyi P, Ssali F, Akondy RS, Anderson J, Schmidt TE, Reimann T, Callisto SP, Schoephoerster J, ... ... Sekaly RP, et al. Lymphoid tissue fibrosis is associated with impaired vaccine responses. The Journal of Clinical Investigation. PMID 29781814 DOI: 10.1172/Jci97377  0.428
2018 Kulpa D, Talla A, Ribeiro S, Barnard R, Hazuda D, Chomont N, Sekaly R. A-108 The Contribution of memory CD4+ T cell subset phenotype to latency reversal efficiency Jaids Journal of Acquired Immune Deficiency Syndromes. 77: 35. DOI: 10.1097/01.Qai.0000532489.63793.5B  0.451
2017 Gavegnano C, Brehm JH, Dupuy FP, Talla A, Ribeiro SP, Kulpa DA, Cameron C, Santos S, Hurwitz SJ, Marconi VC, Routy JP, Sabbagh L, Schinazi RF, Sékaly RP. Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors. Plos Pathogens. 13: e1006740. PMID 29267399 DOI: 10.1371/Journal.Ppat.1006740  0.7
2017 Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, Aid M, Tsui C, Maldonado P, Nair U, Ghneim K, Fallon PG, Sekaly RP, Barouch DH, Shalek AK, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. PMID 29249358 DOI: 10.1016/J.Cell.2017.11.036  0.314
2017 Wu G, Swanson M, Talla A, Graham D, Strizki J, Gorman D, Barnard RJ, Blair W, Søgaard OS, Tolstrup M, Østergaard L, Rasmussen TA, Sekaly RP, Archin NM, Margolis DM, et al. HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal. Jci Insight. 2. PMID 28814661 DOI: 10.1172/Jci.Insight.92901  0.378
2017 Abdelsamed HA, Moustaki A, Fan Y, Dogra P, Ghoneim HE, Zebley CC, Triplett BM, Sekaly RP, Youngblood B. Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis. The Journal of Experimental Medicine. PMID 28490440 DOI: 10.1084/Jem.20161760  0.367
2017 Peterson CW, Benne C, Polacino P, Kaur J, McAllister CE, Filali-Mouhim A, Obenza W, Pecor TA, Huang ML, Baldessari A, Murnane RD, Woolfrey AE, Jerome KR, Hu SL, Klatt NR, et al. Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantation. Jci Insight. 2: e91230. PMID 28239658 DOI: 10.1172/Jci.Insight.91230  0.502
2016 Tomalka J, Ghneim K, Bhattacharyya S, Aid M, Barouch DH, Sekaly RP, Ribeiro SP. The sooner the better: innate immunity as a path toward the HIV cure. Current Opinion in Virology. 19: 85-91. PMID 27497036 DOI: 10.1016/J.Coviro.2016.07.003  0.378
2016 Fromentin R, Bakeman W, Lawani MB, Khoury G, Hartogensis W, DaFonseca S, Killian M, Epling L, Hoh R, Sinclair E, Hecht FM, Bacchetti P, Deeks SG, Lewin SR, Sékaly RP, et al. CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART. Plos Pathogens. 12: e1005761. PMID 27415008 DOI: 10.1371/Journal.Ppat.1005761  0.507
2016 Zhang Y, El-Far M, Dupuy FP, Abdel-Hakeem MS, He Z, Procopio FA, Shi Y, Haddad EK, Ancuta P, Sekaly RP, Said EA. HCV RNA Activates APCs via TLR7/TLR8 While Virus Selectively Stimulates Macrophages Without Inducing Antiviral Responses. Scientific Reports. 6: 29447. PMID 27385120 DOI: 10.1038/Srep29447  0.743
2016 Pandiyan P, Younes SA, Ribeiro SP, Talla A, McDonald D, Bhaskaran N, Levine AD, Weinberg A, Sekaly RP. Mucosal Regulatory T Cells and T Helper 17 Cells in HIV-Associated Immune Activation. Frontiers in Immunology. 7: 228. PMID 27379092 DOI: 10.3389/Fimmu.2016.00228  0.507
2016 Reese TA, Bi K, Kambal A, Filali-Mouhim A, Beura LK, Bürger MC, Pulendran B, Sekaly RP, Jameson SC, Masopust D, Haining WN, Virgin HW. Sequential Infection with Common Pathogens Promotes Human-like Immune Gene Expression and Altered Vaccine Response. Cell Host & Microbe. PMID 27107939 DOI: 10.1016/J.Chom.2016.04.003  0.321
2016 Beura LK, Hamilton SE, Bi K, Schenkel JM, Odumade OA, Casey KA, Thompson EA, Fraser KA, Rosato PC, Filali-Mouhim A, Sekaly RP, Jenkins MK, Vezys V, Haining WN, Jameson SC, et al. Normalizing the environment recapitulates adult human immune traits in laboratory mice. Nature. PMID 27096360 DOI: 10.1038/Nature17655  0.321
2016 Liu J, Haddad EK, Marceau J, Morabito KM, Rao SS, Filali-Mouhim A, Sekaly RP, Graham BS. A Numerically Subdominant CD8 T Cell Response to Matrix Protein of Respiratory Syncytial Virus Controls Infection with Limited Immunopathology. Plos Pathogens. 12: e1005486. PMID 26943673 DOI: 10.1371/Journal.Ppat.1005486  0.524
2015 Cleret-Buhot A, Zhang Y, Planas D, Goulet JP, Monteiro P, Gosselin A, Wacleche VS, Tremblay CL, Jenabian MA, Routy JP, El-Far M, Chomont N, Haddad EK, Sekaly RP, Ancuta P. Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach. Retrovirology. 12: 102. PMID 26654242 DOI: 10.1186/S12977-015-0226-9  0.335
2015 El-Far M, Ancuta P, Routy JP, Zhang Y, Bakeman W, Bordi R, DaFonseca S, Said EA, Gosselin A, Tep TS, Eichbaum Q, van Grevenynghe J, Schwartz O, Freeman GJ, Haddad EK, et al. Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation. The Journal of General Virology. 96: 1463-77. PMID 25626682 DOI: 10.1099/Vir.0.000065  0.544
2015 Roychoudhuri R, Lefebvre F, Honda M, Pan L, Ji Y, Klebanoff CA, Nichols CN, Fourati S, Hegazy AN, Goulet JP, Gattinoni L, Nabel GJ, Gilliet M, Cameron M, Restifo NP, et al. Transcriptional profiles reveal a stepwise developmental program of memory CD8(+) T cell differentiation. Vaccine. 33: 914-23. PMID 25446821 DOI: 10.1016/J.Vaccine.2014.10.007  0.476
2015 Nakanjako D, Ssinabulya I, Nabatanzi R, Bayigga L, Kiragga A, Joloba M, Kaleebu P, Kambugu AD, Kamya MR, Sekaly R, Elliott A, Mayanja-Kizza H. Atorvastatin reduces T-cell activation and exhaustion among HIV-infected cART-treated suboptimal immune responders in Uganda: a randomised crossover placebo-controlled trial. Tropical Medicine & International Health : Tm & Ih. 20: 380-90. PMID 25441397 DOI: 10.1111/tmi.12442  0.367
2015 Nakanjako D, Ssinabulya I, Nabatanzi R, Bayigga L, Kiragga A, Joloba M, Kaleebu P, Kambugu AD, Kamya MR, Sekaly R, Elliott A, Mayanja-Kizza H. Atorvastatin reduces T-cell activation and exhaustion among HIV-infected cART-treated suboptimal immune responders in Uganda: a randomised crossover placebo-controlled trial. Tropical Medicine & International Health : Tm & Ih. 20: 380-90. PMID 25441397 DOI: 10.1111/tmi.12442  0.367
2014 Cockerham LR, Jain V, Sinclair E, Glidden DV, Hartogenesis W, Hatano H, Hunt PW, Martin JN, Pilcher CD, Sekaly R, McCune JM, Hecht FM, Deeks SG. Programmed death-1 expression on CD4⁺ and CD8⁺ T cells in treated and untreated HIV disease. Aids (London, England). 28: 1749-58. PMID 24871455 DOI: 10.1097/Qad.0000000000000314  0.433
2014 Thiébaut R, Drylewicz J, Prague M, Lacabaratz C, Beq S, Jarne A, Croughs T, Sekaly RP, Lederman MM, Sereti I, Commenges D, Lévy Y. Quantifying and predicting the effect of exogenous interleukin-7 on CD4+ T cells in HIV-1 infection. Plos Computational Biology. 10: e1003630. PMID 24853554 DOI: 10.1371/Journal.Pcbi.1003630  0.51
2014 Jacobson JM, Wang H, Bordi R, Zheng L, Gross BH, Landay AL, Spritzler J, Routy JP, Benson C, Aberg J, Tebas P, Haas DW, Tiu J, Coughlin K, Purdue L, ... Sekaly RP, et al. A randomized controlled trial of palifermin (recombinant human keratinocyte growth factor) for the treatment of inadequate CD4+ T-lymphocyte recovery in patients with HIV-1 infection on antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes (1999). 66: 399-406. PMID 24815851 DOI: 10.1097/Qai.0000000000000195  0.416
2013 Phetsouphanh C, Xu Y, Amin J, Seddiki N, Procopio F, Sekaly RP, Zaunders JJ, Kelleher AD. Characterization of transcription factor phenotypes within antigen-specific CD4+ T cells using qualitative multiplex single-cell RT-PCR. Plos One. 8: e74946. PMID 24124462 DOI: 10.1371/Journal.Pone.0074946  0.466
2013 Breton G, Chomont N, Takata H, Fromentin R, Ahlers J, Filali-Mouhim A, Riou C, Boulassel MR, Routy JP, Yassine-Diab B, Sékaly RP. Programmed death-1 is a marker for abnormal distribution of naive/memory T cell subsets in HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 191: 2194-204. PMID 23918986 DOI: 10.4049/Jimmunol.1200646  0.498
2013 Lederman MM, Funderburg NT, Sekaly RP, Klatt NR, Hunt PW. Residual immune dysregulation syndrome in treated HIV infection. Advances in Immunology. 119: 51-83. PMID 23886064 DOI: 10.1016/B978-0-12-407707-2.00002-3  0.459
2013 Goulet ML, Olagnier D, Xu Z, Paz S, Belgnaoui SM, Lafferty EI, Janelle V, Arguello M, Paquet M, Ghneim K, Richards S, Smith A, Wilkinson P, Cameron M, Kalinke U, ... ... Sekaly RP, et al. Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity. Plos Pathogens. 9: e1003298. PMID 23633948 DOI: 10.1371/Journal.Ppat.1003298  0.337
2013 Vandergeeten C, Fromentin R, DaFonseca S, Lawani MB, Sereti I, Lederman MM, Ramgopal M, Routy JP, Sékaly RP, Chomont N. Interleukin-7 promotes HIV persistence during antiretroviral therapy. Blood. 121: 4321-9. PMID 23589672 DOI: 10.1182/Blood-2012-11-465625  0.508
2013 Katlama C, Deeks SG, Autran B, Martinez-Picado J, van Lunzen J, Rouzioux C, Miller M, Vella S, Schmitz JE, Ahlers J, Richman DD, Sekaly RP. Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs. Lancet. 381: 2109-17. PMID 23541541 DOI: 10.1016/S0140-6736(13)60104-X  0.446
2013 Tzelepis F, Joseph J, Haddad EK, Maclean S, Dudani R, Agenes F, Peng SL, Sekaly RP, Sad S. Intrinsic role of FoxO3a in the development of CD8+ T cell memory. Journal of Immunology (Baltimore, Md. : 1950). 190: 1066-75. PMID 23277488 DOI: 10.4049/Jimmunol.1200639  0.408
2012 Doroudchi M, Yegorov O, Baumgartner T, Kernaleguen AE, Breton G, Ndongala ML, Boulassel MR, Routy JP, Bernard NF, Sékaly RP, Yassine-Diab B. Autologous HIV-1 clade-B Nef peptides elicit increased frequency, breadth and function of CD8+ T-cells compared to consensus peptides. Plos One. 7: e49562. PMID 23185362 DOI: 10.1371/Journal.Pone.0049562  0.46
2012 Fukazawa Y, Park H, Cameron MJ, Lefebvre F, Lum R, Coombes N, Mahyari E, Hagen SI, Bae JY, Reyes MD, Swanson T, Legasse AW, Sylwester A, Hansen SG, Smith AT, et al. Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines. Nature Medicine. 18: 1673-81. PMID 22961108 DOI: 10.1038/Nm.2934  0.444
2012 van Grevenynghe J, Cubas RA, DaFonseca S, Metcalf T, Tremblay CL, Trautmann L, Sekaly RP, Schatzle J, Haddad EK. Foxo3a: an integrator of immune dysfunction during HIV infection. Cytokine & Growth Factor Reviews. 23: 215-21. PMID 22748238 DOI: 10.1016/J.Cytogfr.2012.05.008  0.363
2012 Johnson MJ, Petrovas C, Yamamoto T, Lindsay RW, Loré K, Gall JG, Gostick E, Lefebvre F, Cameron MJ, Price DA, Haddad E, Sekaly RP, Seder RA, Koup RA. Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity. Journal of Immunology (Baltimore, Md. : 1950). 188: 6109-18. PMID 22586038 DOI: 10.4049/Jimmunol.1103717  0.438
2012 Lévy Y, Sereti I, Tambussi G, Routy JP, Lelièvre JD, Delfraissy JF, Molina JM, Fischl M, Goujard C, Rodriguez B, Rouzioux C, Avettand-Fenoël V, Croughs T, Beq S, Morre M, ... ... Sekaly RP, et al. Effects of recombinant human interleukin 7 on T-cell recovery and thymic output in HIV-infected patients receiving antiretroviral therapy: results of a phase I/IIa randomized, placebo-controlled, multicenter study. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 55: 291-300. PMID 22550117 DOI: 10.1093/Cid/Cis383  0.681
2012 Ananworanich J, Schuetz A, Vandergeeten C, Sereti I, de Souza M, Rerknimitr R, Dewar R, Marovich M, van Griensven F, Sekaly R, Pinyakorn S, Phanuphak N, Trichavaroj R, Rutvisuttinunt W, Chomchey N, et al. Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection. Plos One. 7: e33948. PMID 22479485 DOI: 10.1371/Journal.Pone.0033948  0.4
2012 Songok EM, Luo M, Liang B, Mclaren P, Kaefer N, Apidi W, Boucher G, Kimani J, Wachihi C, Sekaly R, Fowke K, Ball BT, Plummer FA. Microarray analysis of HIV resistant female sex workers reveal a gene expression signature pattern reminiscent of a lowered immune activation state. Plos One. 7: e30048. PMID 22291902 DOI: 10.1371/Journal.Pone.0030048  0.356
2012 Routy JP, Tremblay CL, Angel JB, Trottier B, Rouleau D, Baril JG, Harris M, Trottier S, Singer J, Chomont N, Sékaly RP, Boulassel MR. Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: results from a multicentre randomized clinical study. Hiv Medicine. 13: 291-6. PMID 22276680 DOI: 10.1111/j.1468-1293.2011.00975.x  0.325
2012 Janbazian L, Price DA, Canderan G, Filali-Mouhim A, Asher TE, Ambrozak DR, Scheinberg P, Boulassel MR, Routy JP, Koup RA, Douek DC, Sekaly RP, Trautmann L. Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation. Journal of Immunology (Baltimore, Md. : 1950). 188: 1156-67. PMID 22210916 DOI: 10.4049/Jimmunol.1102610  0.51
2012 Boulassel MR, Chomont N, Pai NP, Gilmore N, Sékaly RP, Routy JP. CD4 T cell nadir independently predicts the magnitude of the HIV reservoir after prolonged suppressive antiretroviral therapy. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 53: 29-32. PMID 22019250 DOI: 10.1016/J.Jcv.2011.09.018  0.476
2012 Mbitikon-Kobo FM, Bonneville M, Sekaly RP, Trautmann L. Ex vivo measurement of the cytotoxic capacity of human primary antigen-specific CD8 T cells. Journal of Immunological Methods. 375: 252-7. PMID 21996428 DOI: 10.1016/j.jim.2011.09.008  0.387
2012 van Grevenynghe J, Cubas RA, Noto A, DaFonseca S, He Z, Peretz Y, Filali-Mouhim A, Dupuy FP, Procopio FA, Chomont N, Balderas RS, Said EA, Boulassel M, Tremblay CL, Routy J, et al. Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis Journal of Clinical Investigation. 122: 2704-2704. DOI: 10.1172/Jci64981  0.413
2011 Peretz Y, Marra O, Thomas R, Legault D, Côté P, Boulassel MR, Rouleau D, Routy JP, Sékaly RP, Tsoukas CM, Tremblay C, Bernard NF. Relative contribution of HIV-specific functional lymphocyte subsets restricted by protective and non-protective HLA alleles. Viral Immunology. 24: 189-98. PMID 21668360 DOI: 10.1089/Vim.2010.0117  0.369
2011 Malaspina A, Rinaldo CR, Sekaly RP, Flores J, D'Souza PM. "In vitro systems to characterize the immune response to HIV-1 and HIV-1 vaccine candidates", NIAID Workshop Report, Bethesda, August 4, 2010. Vaccine. 29: 4647-53. PMID 21571022 DOI: 10.1016/J.Vaccine.2011.04.035  0.35
2010 Abdel-Hakeem MS, Bédard N, Badr G, Ostrowski M, Sékaly RP, Bruneau J, Willems B, Heathcote EJ, Shoukry NH. Comparison of immune restoration in early versus late alpha interferon therapy against hepatitis C virus. Journal of Virology. 84: 10429-35. PMID 20668076 DOI: 10.1128/Jvi.01094-10  0.78
2010 Ndongala ML, Kamya P, Boulet S, Peretz Y, Rouleau D, Tremblay C, Leblanc R, Côté P, Baril JG, Thomas R, Vézina S, Boulassel MR, Routy JP, Sékaly RP, Bernard NF. Changes in function of HIV-specific T-cell responses with increasing time from infection. Viral Immunology. 23: 159-68. PMID 20373996 DOI: 10.1089/Vim.2009.0084  0.473
2010 Said EA, Dupuy FP, Trautmann L, Zhang Y, Shi Y, El-Far M, Hill BJ, Noto A, Ancuta P, Peretz Y, Fonseca SG, Van Grevenynghe J, Boulassel MR, Bruneau J, Shoukry NH, ... ... Sekaly RP, et al. Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection. Nature Medicine. 16: 452-9. PMID 20208540 DOI: 10.1038/Nm.2106  0.402
2010 Gosselin A, Monteiro P, Chomont N, Diaz-Griffero F, Said EA, Fonseca S, Wacleche V, El-Far M, Boulassel MR, Routy JP, Sekaly RP, Ancuta P. Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 184: 1604-16. PMID 20042588 DOI: 10.4049/Jimmunol.0903058  0.501
2010 Routy JP, Boulassel MR, Yassine-Diab B, Nicolette C, Healey D, Jain R, Landry C, Yegorov O, Tcherepanova I, Monesmith T, Finke L, Sékaly RP. Immunologic activity and safety of autologous HIV RNA-electroporated dendritic cells in HIV-1 infected patients receiving antiretroviral therapy. Clinical Immunology (Orlando, Fla.). 134: 140-7. PMID 19889582 DOI: 10.1016/J.Clim.2009.09.009  0.47
2010 Saïdi H, Carbonneil C, Magri G, Eslahpazir J, Sekaly RP, Bélec L. Differential modulation of CCR5-tropic human immunodeficiency virus-1 transfer from macrophages towards T cells under interleukin-4/interleukin-13 microenvironment. Human Immunology. 71: 1-13. PMID 19706316 DOI: 10.1016/J.Humimm.2009.08.011  0.335
2009 Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, Yassine-Diab B, Boucher G, Boulassel MR, Ghattas G, Brenchley JM, Schacker TW, Hill BJ, Douek DC, Routy JP, Haddad EK, et al. HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nature Medicine. 15: 893-900. PMID 19543283 DOI: 10.1038/Nm.1972  0.542
2009 Oyugi JO, Vouriot FC, Alimonti J, Wayne S, Luo M, Land AM, Ao Z, Yao X, Sekaly RP, Elliott LJ, Simonsen JN, Ball TB, Jaoko W, Kimani J, Plummer FA, et al. A common CD4 gene variant is associated with an increased risk of HIV-1 infection in Kenyan female commercial sex workers. The Journal of Infectious Diseases. 199: 1327-34. PMID 19301975 DOI: 10.1086/597616  0.421
2009 Dekaban GA, Snir J, Shrum B, de Chickera S, Willert C, Merrill M, Said EA, Sekaly RP, Foster PJ, O'Connell PJ. Semiquantitation of mouse dendritic cell migration in vivo using cellular MRI. Journal of Immunotherapy (Hagerstown, Md. : 1997). 32: 240-51. PMID 19242376 DOI: 10.1097/Cji.0B013E318197B2A0  0.31
2009 Ndongala ML, Peretz Y, Boulet S, Doroudchi M, Yassine-Diab B, Boulassel MR, Rouleau D, Tremblay C, LeBlanc R, Routy JP, Sékaly RP, Bernard NF. HIV Gag p24 specific responses secreting IFN-gamma and/or IL-2 in treatment-naïve individuals in acute infection early disease (AIED) are associated with low viral load. Clinical Immunology (Orlando, Fla.). 131: 277-87. PMID 19135418 DOI: 10.1016/J.Clim.2008.11.006  0.426
2008 Gaucher D, Therrien R, Kettaf N, Angermann BR, Boucher G, Filali-Mouhim A, Moser JM, Mehta RS, Drake DR, Castro E, Akondy R, Rinfret A, Yassine-Diab B, Said EA, Chouikh Y, et al. Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses. The Journal of Experimental Medicine. 205: 3119-31. PMID 19047440 DOI: 10.1084/Jem.20082292  0.335
2008 van Grevenynghe J, Halwani R, Chomont N, Ancuta P, Peretz Y, Tanel A, Procopio FA, shi Y, Said EA, Haddad EK, Sekaly RP. Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection. Seminars in Immunology. 20: 196-203. PMID 18757210 DOI: 10.1016/J.Smim.2008.07.008  0.326
2008 Badr G, Bédard N, Abdel-Hakeem MS, Trautmann L, Willems B, Villeneuve JP, Haddad EK, Sékaly RP, Bruneau J, Shoukry NH. Early interferon therapy for hepatitis C virus infection rescues polyfunctional, long-lived CD8+ memory T cells. Journal of Virology. 82: 10017-31. PMID 18667516 DOI: 10.1128/Jvi.01083-08  0.791
2008 Mercier F, Boulassel MR, Yassine-Diab B, Tremblay C, Bernard NF, Sekaly RP, Routy JP. Persistent human immunodeficiency virus-1 antigenaemia affects the expression of interleukin-7Rα on central and effector memory CD4 + and CD8+ T cell subsets Clinical and Experimental Immunology. 152: 72-80. PMID 18279439 DOI: 10.1111/j.1365-2249.2008.03610.x  0.367
2008 Abdel-Hakeem MS, Bédard N, Badr G, Ostrowski M, Bruneau J, Sékaly RP, Willems B, Heathcote JE, Shoukry NH. 265 Early but not late interferon alpha therapy against hepatitis C rescues polyfunctional CD4+ and CD8+ memory T cells Cytokine. 43: 306-307. DOI: 10.1016/J.Cyto.2008.07.347  0.768
2007 Wang C, Wen T, Routy JP, Bernard NF, Sekaly RP, Watts TH. 4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 8252-63. PMID 18056369 DOI: 10.4049/Jimmunol.179.12.8252  0.528
2007 Peretz Y, Ndongala ML, Boulet S, Boulassel MR, Rouleau D, Côté P, Longpré D, Routy JP, Falutz J, Tremblay C, Tsoukas CM, Sékaly RP, Bernard NF. Functional T cell subsets contribute differentially to HIV peptide-specific responses within infected individuals: correlation of these functional T cell subsets with markers of disease progression. Clinical Immunology (Orlando, Fla.). 124: 57-68. PMID 17521962 DOI: 10.1016/J.Clim.2007.04.004  0.443
2007 Boulet S, Ndongala ML, Peretz Y, Boisvert MP, Boulassel MR, Tremblay C, Routy JP, Sekaly RP, Bernard NF. A dual color ELISPOT method for the simultaneous detection of IL-2 and IFN-gamma HIV-specific immune responses. Journal of Immunological Methods. 320: 18-29. PMID 17222422 DOI: 10.1016/J.Jim.2006.11.010  0.362
2007 Younes SA, Trautmann L, Yassine-Diab B, Kalfayan LH, Kernaleguen AE, Cameron TO, Boulassel R, Stern LJ, Routy JP, Grossman Z, Dumont AR, Sekaly RP. The duration of exposure to HIV modulates the breadth and the magnitude of HIV-specific memory CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 788-97. PMID 17202340 DOI: 10.4049/Jimmunol.178.2.788  0.634
2007 Dion ML, Bordi R, Zeidan J, Asaad R, Boulassel MR, Routy JP, Lederman MM, Sekaly RP, Cheynier R. Slow disease progression and robust therapy-mediated CD4+ T-cell recovery are associated with efficient thymopoiesis during HIV-1 infection. Blood. 109: 2912-20. PMID 17164338 DOI: 10.1182/Blood-2006-09-047308  0.427
2007 Trautmann L, Said EA, Halwani R, Janbazian L, Chomont N, El-Far M, Breton G, Haddad EK, Sekaly RP. Programmed death 1: A critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections Current Opinion in Hiv and Aids. 2: 219-227. DOI: 10.1097/COH.0b013e3280ebb5c9  0.359
2006 Riou C, Dumont AR, Yassine-Diab B, Haddad EK, Sekaly RP. IL-4 influences the differentiation and the susceptibility to activation-induced cell death of human naive CD8+ T cells. International Immunology. 18: 827-35. PMID 16611649 DOI: 10.1093/Intimm/Dxl019  0.551
2005 Bukczynski J, Wen T, Wang C, Christie N, Routy JP, Boulassel MR, Kovacs CM, Macdonald KS, Ostrowski M, Sekaly RP, Bernard NF, Watts TH. Enhancement of HIV-specific CD8 T cell responses by dual costimulation with CD80 and CD137L. Journal of Immunology (Baltimore, Md. : 1950). 175: 6378-89. PMID 16272290 DOI: 10.4049/Jimmunol.175.10.6378  0.559
2005 Serghides L, Bukczynski J, Wen T, Wang C, Routy JP, Boulassel MR, Sekaly RP, Ostrowski M, Bernard NF, Watts TH. Evaluation of OX40 ligand as a costimulator of human antiviral memory CD8 T cell responses: comparison with B7.1 and 4-1BBL. Journal of Immunology (Baltimore, Md. : 1950). 175: 6368-77. PMID 16272289 DOI: 10.4049/Jimmunol.175.10.6368  0.515
2005 Maecker HT, Rinfret A, D'Souza P, Darden J, Roig E, Landry C, Hayes P, Birungi J, Anzala O, Garcia M, Harari A, Frank I, Baydo R, Baker M, Holbrook J, ... ... Sekaly RP, et al. Standardization of cytokine flow cytometry assays Bmc Immunology. 6. PMID 15978127 DOI: 10.1186/1471-2172-6-13  0.368
2005 Rose JJ, Janvier K, Chandrasekhar S, Sekaly RP, Bonifacino JS, Venkatesan S. CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms. The Journal of Biological Chemistry. 280: 7413-26. PMID 15611114 DOI: 10.1074/Jbc.M409420200  0.361
2004 Routy JP, Machouf N, Edwardes MD, Brenner BG, Thomas R, Trottier B, Rouleau D, Tremblay CL, Côté P, Baril JG, Remis RS, Sékaly RP, Wainberg MA. Factors associated with a decrease in the prevalence of drug resistance in newly HIV-1 infected individuals in Montreal. Aids (London, England). 18: 2305-12. PMID 15577543 DOI: 10.1097/00002030-200411190-00011  0.33
2004 Aouad SM, Cohen LY, Sharif-Askari E, Haddad EK, Alam A, Sekaly RP. Caspase-3 is a component of Fas death-inducing signaling complex in lipid rafts and its activity is required for complete caspase-8 activation during Fas-mediated cell death. Journal of Immunology (Baltimore, Md. : 1950). 172: 2316-23. PMID 14764700 DOI: 10.4049/Jimmunol.172.4.2316  0.701
2003 Altfeld M, Addo MM, Rosenberg ES, Hecht FM, Lee PK, Vogel M, Yu XG, Draenert R, Johnston MN, Strick D, Allen TM, Feeney ME, Kahn JO, Sekaly RP, Levy JA, et al. Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection. Aids (London, England). 17: 2581-91. PMID 14685052 DOI: 10.1097/00002030-200312050-00005  0.411
2003 Younes SA, Yassine-Diab B, Dumont AR, Boulassel MR, Grossman Z, Routy JP, Sekaly RP. HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity. The Journal of Experimental Medicine. 198: 1909-22. PMID 14676302 DOI: 10.1084/Jem.20031598  0.615
2003 Agadjanyan MG, Chattergoon MA, Holterman MJ, Monzavi-Karbassi B, Kim JJ, Dentchev T, Wilson D, Ayyavoo V, Montaner LJ, Kieber-Emmons T, Sekaly RP, Weiner DB. Costimulatory molecule immune enhancement in a plasmid vaccine model is regulated in part through the Ig constant-like domain of CD80/86. Journal of Immunology (Baltimore, Md. : 1950). 171: 4311-9. PMID 14530356 DOI: 10.4049/Jimmunol.171.8.4311  0.414
2003 D'Souza S, McGrath H, Sékaly RP. Early activation events differentiate the reactivity of two T-cell families to Staphylococcus enterotoxin A. Cellular Immunology. 223: 113-9. PMID 14527509 DOI: 10.1016/S0008-8749(03)00156-4  0.366
2003 Iyasere C, Tilton JC, Johnson AJ, Younes S, Yassine-Diab B, Sekaly RP, Kwok WW, Migueles SA, Laborico AC, Shupert WL, Hallahan CW, Davey RT, Dybul M, Vogel S, Metcalf J, et al. Diminished proliferation of human immunodeficiency virus-specific CD4+ T cells is associated with diminished interleukin-2 (IL-2) production and is recovered by exogenous IL-2. Journal of Virology. 77: 10900-9. PMID 14512540 DOI: 10.1128/Jvi.77.20.10900-10909.2003  0.531
2003 Boulassel MR, Spurll G, Rouleau D, Tremblay C, Edwardes M, Sekaly RP, Lalonde R, Routy JP. Changes in immunological and virological parameters in HIV-1 infected subjects following leukapheresis Journal of Clinical Apheresis. 18: 55-60. PMID 12874816 DOI: 10.1002/jca.10051  0.381
2003 Alter G, Hatzakis G, Tsoukas CM, Pelley K, Rouleau D, LeBlanc R, Baril JG, Dion H, Lefebvre E, Thomas R, Côté P, Lapointe N, Routy JP, Sékaly RP, Conway B, et al. Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection. Journal of Immunology (Baltimore, Md. : 1950). 171: 477-88. PMID 12817033 DOI: 10.4049/Jimmunol.171.1.477  0.357
2003 Geenen V, Poulin JF, Dion ML, Martens H, Castermans E, I Hansenne, Moutschen M, Sékaly RP, Cheynier R. Quantification of T cell receptor rearrangement excision circles to estimate thymic function: an important new tool for endocrine-immune physiology. The Journal of Endocrinology. 176: 305-11. PMID 12630915 DOI: 10.1677/joe.0.1760305  0.567
2003 Bernardin F, Doukhan L, Longone-Miller A, Champagne P, Sekaly R, Delwart E. Estimate of the total number of CD8+ clonal expansions in healthy adults using a new DNA heteroduplex-tracking assay for CDR3 repertoire analysis. Journal of Immunological Methods. 274: 159-75. PMID 12609542 DOI: 10.1016/S0022-1759(02)00514-8  0.452
2003 Boyer JD, Kutzler MA, Chattergoon MA, Calarota SA, Pavlakis G, Sekaly RP, MacGregor RR, Weiner DB. Engineering DNA vaccination as an approach to HIV immune therapy Clinical and Applied Immunology Reviews. 3: 183-197. DOI: 10.1016/S1529-1049(02)00158-7  0.415
2002 Boyer JD, Chattergoon M, Muthumani K, Kudchodkar S, Kim J, Bagarazzi M, Pavlakis G, Sekaly R, Weiner DB. Next generation DNA vaccines for HIV-1. Journal of Liposome Research. 12: 137-42. PMID 12604047 DOI: 10.1081/Lpr-120004786  0.357
2002 Nie Z, Phenix BN, Lum JJ, Alam A, Lynch DH, Beckett B, Krammer PH, Sekaly RP, Badley AD. HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation Cell Death and Differentiation. 9: 1172-1184. PMID 12404116 DOI: 10.1038/Sj.Cdd.4401094  0.315
2001 Champagne P, Dumont AR, Sékaly RP. Learning to remember: generation and maintenance of T-cell memory. Dna and Cell Biology. 20: 745-60. PMID 11879568 DOI: 10.1089/104454901753438561  0.494
2001 Sharif-Askari E, Alam A, Rhéaume E, Beresford PJ, Scotto C, Sharma K, Lee D, DeWolf WE, Nuttall ME, Lieberman J, Sékaly RP. Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation. The Embo Journal. 20: 3101-13. PMID 11406587 DOI: 10.1093/Emboj/20.12.3101  0.709
2001 Goulder PJ, Altfeld MA, Rosenberg ES, Nguyen T, Tang Y, Eldridge RL, Addo MM, He S, Mukherjee JS, Phillips MN, Bunce M, Kalams SA, Sekaly RP, Walker BD, Brander C. Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection. The Journal of Experimental Medicine. 193: 181-94. PMID 11148222 DOI: 10.1084/Jem.193.2.181  0.437
2001 Cameron TO, Cochran JR, Yassine-Diab B, Sékaly RP, Stern LJ. Cutting edge: detection of antigen-specific CD4+ T cells by HLA-DR1 oligomers is dependent on the T cell activation state. Journal of Immunology (Baltimore, Md. : 1950). 166: 741-5. PMID 11145645 DOI: 10.4049/Jimmunol.166.2.741  0.352
2000 Altfeld MA, Trocha A, Eldridge RL, Rosenberg ES, Phillips MN, Addo MM, Sekaly RP, Kalams SA, Burchett SA, McIntosh K, Walker BD, Goulder PJ. Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay. Journal of Virology. 74: 8541-9. PMID 10954555 DOI: 10.1128/Jvi.74.18.8541-8549.2000  0.374
2000 Gratton S, Haughn L, Sekaly RP, Julius M. The extracellular domain of CD4 regulates the initiation of T cell activation Molecular Immunology. 37: 213-219. PMID 10930628 DOI: 10.1016/S0161-5890(00)00046-8  0.317
2000 Soudeyns H, Champagne P, Holloway CL, Silvestri GU, Ringuette N, Samson J, Lapointe N, Sékaly RP. Transient T cell receptor β-chain variable region-specific expansions of CD4+ and CD8+ T cells during the early phase of pediatric human immunodeficiency virus infection: Characterization of expanded cell populations by T cell receptor phenotyping Journal of Infectious Diseases. 181: 107-120. PMID 10608757 DOI: 10.1086/315181  0.437
1999 Poulin JF, Viswanathan MN, Harris JM, Komanduri KV, Wieder E, Ringuette N, Jenkins M, McCune JM, Sékaly RP. Direct evidence for thymic function in adult humans. The Journal of Experimental Medicine. 190: 479-86. PMID 10449519 DOI: 10.1084/Jem.190.4.479  0.636
1999 Poulin JF, Sékaly RP. Function of the thymus in HIV-infected adults. Jama. 282: 219. PMID 10422975 DOI: 10.1001/Jama.282.3.219  0.663
1998 Gratton S, Julius M, Sekaly RP. lck-independent inhibition of T cell antigen response by the HIV gp120 Journal of Immunology. 161: 3551-3556. PMID 9759876  0.367
1998 Pantaleo G, Soudeyns H, Demarest JF, Vaccarezza M, Graziosi C, Paolucci S, Daucher MB, Cohen OJ, Denis F, Biddison WE, Sekaly RP, Fauci AS. Accumulation of human immunodeficiency virus-specific cytotoxic T lymphocytes away from the predominant site of virus replication during primary infection. European Journal of Immunology. 27: 3166-73. PMID 9464802 DOI: 10.1002/eji.1830271213  0.353
1997 Pantaleo G, Soudeyns H, Demarest JF, Vaccarezza M, Graziosi C, Paolucci S, Daucher M, Cohen OJ, Denis F, Biddison WE, Sekaly RP, Fauci AS. Evidence for rapid disappearance of initially expanded HIV-specific CD8+ T cell clones during primary HIV infection. Proceedings of the National Academy of Sciences of the United States of America. 94: 9848-53. PMID 9275214 DOI: 10.1073/Pnas.94.18.9848  0.508
1997 Pantaleo G, Demarest JF, Schacker T, Vaccarezza M, Cohen OJ, Daucher M, Graziosi C, Schnittman SS, Quinn TC, Shaw GM, Perrin L, Tambussi G, Lazzarin A, Sekaly RP, Soudeyns H, et al. The qualitative nature of the primary immune response to HIV infection is a prognosticator of disease progression independent of the initial level of plasma viremia. Proceedings of the National Academy of Sciences of the United States of America. 94: 254-8. PMID 8990195 DOI: 10.1073/Pnas.94.1.254  0.387
1996 Sutkowski N, Palkama T, Ciurli C, Sekaly RP, Thorley-Lawson DA, Huber BT. An Epstein-Barr virus-associated superantigen Journal of Experimental Medicine. 184: 971-980. PMID 9064357 DOI: 10.1084/Jem.184.3.971  0.386
1996 Silvestri G, Soudeyns H, Samson J, Denis F, Lapointe N, Sekaly RP. T-cell receptor Vβ-specific expansions in children from HIV-infected mothers [4] Aids. 10: 549-551. PMID 8724051 DOI: 10.1097/00002030-199605000-00018  0.304
1996 Duplay P, Alcover A, Fargeas C, Sékaly RP, Branton PE. An activated epidermal growth factor receptor/Lck chimera restores early T cell receptor-mediated calcium response in a CD45-deficient T cell line Journal of Biological Chemistry. 271: 17896-17902. PMID 8663450 DOI: 10.1074/Jbc.271.30.17896  0.312
1994 Zerbib AC, Reske-Kunz AB, Lock P, Sékaly RP. CD4-mediated enhancement or inhibition of T cell activation does not require the CD4:p56lck association. The Journal of Experimental Medicine. 179: 1973-83. PMID 8195720 DOI: 10.1084/jem.179.6.1973  0.356
1994 Graziosi C, Pantaleo G, Gantt KR, Fortin JP, Demarest JF, Cohen OJ, Sékaly RP, Fauci AS. Lack of evidence for the dichotomy of TH1 and TH2 predominance in HIV-infected individuals. Science (New York, N.Y.). 265: 248-52. PMID 8023143 DOI: 10.1126/Science.8023143  0.333
1994 Rebai N, Pantaleo G, Demarest JF, Ciurli C, Soudeyns H, Adelsberger JW, Vaccarezza M, Walker RE, Sekaly RP, Fauci AS. Analysis of the T-cell receptor β-chain variable-region (Vβ) repertoire in monozygotic twins discordant for human immunodeficiency virus: Evidence for perturbations of specific Vβ segments in CD4+ T cells of the virus-positive twins Proceedings of the National Academy of Sciences of the United States of America. 91: 1529-1533. PMID 7906416 DOI: 10.1073/Pnas.91.4.1529  0.462
1994 Tremblay M, Meloche S, Gratton S, Wainberg M, Sékaly R. Association of p56lck with the cytoplasmic domain of CD4 modulates HIV-1 expression. The Embo Journal. 13: 774-783. DOI: 10.1002/J.1460-2075.1994.Tb06320.X  0.382
1993 Labrecque N, McGrath H, Subramanyam M, Huber BT, Sekaly RP. Human T cells respond to mouse mammary tumor virus-encoded superantigen: Vβ restriction and conserved evolutionary features Journal of Experimental Medicine. 177: 1735-1743. PMID 8388432 DOI: 10.1084/Jem.177.6.1735  0.318
1993 Hivroz C, Mazerolles F, Soula M, Fagard R, Graton S, Meloche S, Sekaly RP, Fischer A. Human immunodeficiency virus gp120 and derived peptides activate protein tyrosine kinase p56lck in human CD4 T lymphocytes European Journal of Immunology. 23: 600-607. PMID 7680610  0.316
1992 Paquette Y, Doyon L, Laperrière A, Hanna Z, Ball J, Sekaly RP, Jolicoeur P. A viral long terminal repeat expressed in CD4+CD8+ precursors is downregulated in mature peripheral CD4-CD8+ or CD4+CD8- T cells. Molecular and Cellular Biology. 12: 3522-30. PMID 1321339 DOI: 10.1128/mcb.12.8.3522-3530.1992  0.309
1991 Sekaly RP, Croteau G, Bowman M, Scholl P, Burakoff S, Geha RS. The CD4 molecule is not always required for the T cell response to bacterial enterotoxins Journal of Experimental Medicine. 173: 367-371. PMID 1988539 DOI: 10.1084/Jem.173.2.367  0.367
1991 Carrel S, Salvi S, Rafti F, Favrot M, Rapin C, Sekaly RP. Direct involvement of CD7 (gp40) in activation of TcR γ/δ+ T cells European Journal of Immunology. 21: 1195-1200. PMID 1709867 DOI: 10.1002/Eji.1830210515  0.446
1991 Biassoni R, Ferrini S, Prigione I, Pelak VS, Sekaly RP, Long EO. Activated CD3- CD16+ natural killer cells express a subset of the lymphokine genes induced in activated αβ+ and γδ+ T cells Scandinavian Journal of Immunology. 33: 247-252. PMID 1707180 DOI: 10.1111/j.1365-3083.1991.tb01769.x  0.347
1991 Carrel S, Salvi S, Gallay P, Rapin C, Sekaly RP. Positive signal transduction via surface CD4 molecules does not need coexpression of the CD3/TcR complex Research in Immunology. 142: 97-108. PMID 1678202 DOI: 10.1016/0923-2494(91)90017-D  0.304
1990 Tremblay M, Meloche S, Sekaly RP, Wainberg MA. Complement receptor 2 mediates enhancement of human immunodeficiency virus 1 infection in epstein-barr virus-carrying B cells Journal of Experimental Medicine. 171: 1791-1796. PMID 2159052 DOI: 10.1084/Jem.171.5.1791  0.35
1990 Kanagawa O, Nakauchi H, Sekaly RP, Maeda K, Takagaki Y. Expression and function of the tranfected CD8α chain in murine T cell hybridomas International Immunology. 2: 957-964. PMID 2127694 DOI: 10.1093/Intimm/2.10.957  0.364
1989 Jacobson S, Sekaly RP, Jacobson CL, McFarland HF, Long EO. HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells Journal of Virology. 63: 1756-1762. PMID 2784508 DOI: 10.1128/Jvi.63.4.1756-1762.1989  0.339
1989 Biassoni R, Ferrini S, Sekaly RP, Long EO. Transcription of unrearranged T cell receptor δ genes in CD3- major histocompatibility complex-unrestricted cytotoxic cells European Journal of Immunology. 19: 1973-1976. PMID 2479569 DOI: 10.1002/Eji.1830191034  0.398
1989 Carrel S, Lamarre D, Isler P, Rapin C, Fleury S, Salvi S, Sekaly RP, Cerottini JC. A positive signal is transduced via surface CD4 molecules Research in Immunology. 140: 545-561. PMID 2476842 DOI: 10.1016/0923-2494(89)90119-3  0.314
1988 Sekaly RP, Jacobson S, Richert JR, Tonnelle C, McFarland HF, Long EO. Antigen presentation to HLA class II-restricted measles virus-specific T-cell clones can occur in the absence of the invariant chain Proceedings of the National Academy of Sciences of the United States of America. 85: 1209-1212. PMID 3257576 DOI: 10.1073/Pnas.85.4.1209  0.367
1988 Rothbard JB, Lechler RI, Howland K, Bal V, Eckels DD, Sekaly R, Long EO, Taylor WR, Lamb JR. Structural model of HLA-DR1 restricted T cell antigen recognition. Cell. 52: 515-523. PMID 2963699 DOI: 10.1016/0092-8674(88)90464-3  0.335
1988 Eckels DD, Sell TW, Long EO, Sekaly RP. Presentation of influenza hemagglutinin peptide in the presence of limited allostimulation by HLA-DR1 transfected human fibroblasts Human Immunology. 21: 173-181. PMID 2453491 DOI: 10.1016/0198-8859(88)90069-9  0.315
1987 Gay D, Maddon P, Sekaly R, Talle MA, Godfrey M, Long E, Goldstein G, Chess L, Axel R, Kappler J. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature. 328: 626-9. PMID 3112582 DOI: 10.1038/328626A0  0.448
1987 Ferrini S, Bottino C, Biassoni R, Poggi A, Sekaly RP, Moretta L, Moretta A. Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor γ gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery Journal of Experimental Medicine. 166: 277-282. PMID 3110350 DOI: 10.1084/Jem.166.1.277  0.445
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