Thomas J. Kelly - Publications

Affiliations: 
Molecular Biology Memorial Sloan Kettering Cancer Center, Rockville Centre, NY, United States 
Area:
DNA replication
Website:
http://www.mskcc.org/mskcc/html/12507.cfm

80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Xiao Y, Zhang H, Ramsey A, Karki U, Akana L, Xie JY, Xu J, Kelly T, Ono S, Zhou G. Dynamic Phosphorylation and Dephosphorylation of CAP1 (Cyclase‐Associated Protein 1) by Antagonistic Signaling through CDK5 and cAMP are Critical for the Protein Functions in Actin Filament Disassembly and Cell Adhesion The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02818  0.313
2019 Zhang H, Ramsey A, Xiao Y, Karki U, Xie JY, Xu J, Kelly T, Ono S, Zhou GL. Dynamic phosphorylation and dephosphorylation of CAP1 (Cyclase-Associated Protein 1) by antagonistic signaling through CDK5 and cAMP are critical for the protein functions in actin filament disassembly and cell adhesion. Molecular and Cellular Biology. PMID 31791978 DOI: 10.1128/Mcb.00282-19  0.35
2019 Wu H, Hasan R, Zhang H, Gray J, Williams D, Miller M, Allen F, Lee V, Kelly T, Zhou GL. Phosphorylation Regulates CAP1 (Cyclase-Associated Protein 1) Functions in the Motility and Invasion of Pancreatic Cancer Cells. Scientific Reports. 9: 4925. PMID 30894654 DOI: 10.1038/S41598-019-41346-3  0.338
2019 Kelly T, Callegari AJ. Dynamics of DNA replication in a eukaryotic cell. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718387 DOI: 10.1073/pnas.1818680116  0.586
2019 Hu MD, Patterson AM, Kelly TJ, Watson A, Edelblum KL. 88 – A Novel Role for ΓH Intraepithelial Lymphocytes in the Regulation of Pathological Epithelial Cell Shedding Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)36822-2  0.301
2017 Kelly T. Historical Perspective of Eukaryotic DNA Replication. Advances in Experimental Medicine and Biology. 1042: 1-41. PMID 29357051 DOI: 10.1007/978-981-10-6955-0_1  0.306
2015 Callegari AJ, Kelly TJ. Coordination of DNA damage tolerance mechanisms with cell cycle progression in fission yeast. Cell Cycle (Georgetown, Tex.). 0. PMID 26652183 DOI: 10.1080/15384101.2015.1121353  0.629
2014 Wu M, Lu W, Santos RE, Frattini MG, Kelly TJ. Geminin inhibits a late step in the formation of human pre-replicative complexes. The Journal of Biological Chemistry. 289: 30810-21. PMID 25231993 DOI: 10.1074/Jbc.M114.552935  0.615
2012 Kelly T, Huang Y, Simms AE, Mazur A. Fibroblast activation protein-α: a key modulator of the microenvironment in multiple pathologies. International Review of Cell and Molecular Biology. 297: 83-116. PMID 22608558 DOI: 10.1016/B978-0-12-394308-8.00003-0  0.321
2011 Huang Y, Simms AE, Mazur A, Wang S, León NR, Jones B, Aziz N, Kelly T. Fibroblast activation protein-α promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions. Clinical & Experimental Metastasis. 28: 567-79. PMID 21604185 DOI: 10.1007/S10585-011-9392-X  0.312
2010 Monzavi-Karbassi B, Hine RJ, Stanley JS, Ramani VP, Carcel-Trullols J, Whitehead TL, Kelly T, Siegel ER, Artaud C, Shaaf S, Saha R, Jousheghany F, Henry-Tillman R, Kieber-Emmons T. Fructose as a carbon source induces an aggressive phenotype in MDA-MB-468 breast tumor cells. International Journal of Oncology. 37: 615-22. PMID 20664930 DOI: 10.3892/Ijo_00000710  0.311
2010 Callegari AJ, Clark E, Pneuman A, Kelly TJ. Postreplication gaps at UV lesions are signals for checkpoint activation. Proceedings of the National Academy of Sciences of the United States of America. 107: 8219-24. PMID 20404181 DOI: 10.1073/pnas.1003449107  0.628
2009 Xu YJ, Kelly TJ. Autoinhibition and autoactivation of the DNA replication checkpoint kinase Cds1. The Journal of Biological Chemistry. 284: 16016-27. PMID 19357077 DOI: 10.1074/Jbc.M900785200  0.548
2008 Naito A, Cook CC, Mizumachi T, Wang M, Xie CH, Evans TT, Kelly T, Higuchi M. Progressive tumor features accompany epithelial-mesenchymal transition induced in mitochondrial DNA-depleted cells. Cancer Science. 99: 1584-8. PMID 18754870 DOI: 10.1111/J.1349-7006.2008.00879.X  0.332
2008 Houchens CR, Lu W, Chuang RY, Frattini MG, Fuller A, Simancek P, Kelly TJ. Multiple mechanisms contribute to Schizosaccharomyces pombe origin recognition complex-DNA interactions. The Journal of Biological Chemistry. 283: 30216-24. PMID 18723846 DOI: 10.1074/Jbc.M802649200  0.523
2008 Houchens CR, Perreault A, Bachand F, Kelly TJ. Schizosaccharomyces pombe Noc3 is essential for ribosome biogenesis and cell division but not DNA replication. Eukaryotic Cell. 7: 1433-40. PMID 18606828 DOI: 10.1128/Ec.00119-08  0.381
2007 Callegari AJ, Kelly TJ. Shedding light on the DNA damage checkpoint. Cell Cycle (Georgetown, Tex.). 6: 660-6. PMID 17387276  0.607
2006 Callegari AJ, Kelly TJ. UV irradiation induces a postreplication DNA damage checkpoint. Proceedings of the National Academy of Sciences of the United States of America. 103: 15877-82. PMID 17043220 DOI: 10.1073/pnas.0607343103  0.624
2006 Xu YJ, Davenport M, Kelly TJ. Two-stage mechanism for activation of the DNA replication checkpoint kinase Cds1 in fission yeast. Genes & Development. 20: 990-1003. PMID 16618806 DOI: 10.1101/Gad.1406706  0.523
2005 Sanderson RD, Yang Y, Kelly T, MacLeod V, Dai Y, Theus A. Enzymatic remodeling of heparan sulfate proteoglycans within the tumor microenvironment: growth regulation and the prospect of new cancer therapies. Journal of Cellular Biochemistry. 96: 897-905. PMID 16149080 DOI: 10.1002/Jcb.20602  0.301
2005 Kelly T, Suva LJ, Huang Y, Macleod V, Miao HQ, Walker RC, Sanderson RD. Expression of heparanase by primary breast tumors promotes bone resorption in the absence of detectable bone metastases. Cancer Research. 65: 5778-84. PMID 15994953 DOI: 10.1158/0008-5472.Can-05-0749  0.303
2005 Monzavi-Karbassi B, Whitehead TL, Jousheghany F, Artaud C, Hennings L, Shaaf S, Slaughter A, Korourian S, Kelly T, Blaszczyk-Thurin M, Kieber-Emmons T. Deficiency in surface expression of E-selectin ligand promotes lung colonization in a mouse model of breast cancer. International Journal of Cancer. Journal International Du Cancer. 117: 398-408. PMID 15906360 DOI: 10.1002/Ijc.21192  0.313
2005 Dai J, Chuang RY, Kelly TJ. DNA replication origins in the Schizosaccharomyces pombe genome. Proceedings of the National Academy of Sciences of the United States of America. 102: 337-42. PMID 15623550 DOI: 10.1073/Pnas.0408811102  0.639
2003 Goodman JD, Rozypal TL, Kelly T. Seprase, a membrane-bound protease, alleviates the serum growth requirement of human breast cancer cells. Clinical & Experimental Metastasis. 20: 459-470. PMID 14524536 DOI: 10.1023/A:1025493605850  0.307
2003 Vashee S, Cvetic C, Lu W, Simancek P, Kelly TJ, Walter JC. Sequence-independent DNA binding and replication initiation by the human origin recognition complex. Genes & Development. 17: 1894-908. PMID 12897055 DOI: 10.1101/Gad.1084203  0.525
2003 Chen WT, Kelly T. Seprase complexes in cellular invasiveness. Cancer Metastasis Reviews. 22: 259-69. PMID 12785000 DOI: 10.1023/A:1023055600919  0.323
2003 Chen WT, Kelly T, Ghersi G. DPPIV, seprase, and related serine peptidases in multiple cellular functions. Current Topics in Developmental Biology. 54: 207-32. PMID 12696751 DOI: 10.1016/S0070-2153(03)54010-8  0.302
2002 Chuang RY, Chretien L, Dai J, Kelly TJ. Purification and characterization of the Schizosaccharomyces pombe origin recognition complex: interaction with origin DNA and Cdc18 protein. The Journal of Biological Chemistry. 277: 16920-7. PMID 11850415 DOI: 10.1074/jbc.M107710200  0.624
2001 Gopalakrishnan V, Simancek P, Houchens C, Snaith HA, Frattini MG, Sazer S, Kelly TJ. Redundant control of rereplication in fission yeast. Proceedings of the National Academy of Sciences of the United States of America. 98: 13114-9. PMID 11606752 DOI: 10.1073/Pnas.221467598  0.35
2000 Brush GS, Kelly TJ. Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response. Nucleic Acids Research. 28: 3725-32. PMID 11000264 DOI: 10.1093/Nar/28.19.3725  0.384
2000 Kelly TJ, Brown GW. Regulation of chromosome replication. Annual Review of Biochemistry. 69: 829-80. PMID 10966477 DOI: 10.1146/Annurev.Biochem.69.1.829  0.581
1999 Brown GW, Kelly TJ. Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 96: 8443-8. PMID 10411894 DOI: 10.1073/Pnas.96.15.8443  0.615
1999 Chuang RY, Kelly TJ. The fission yeast homologue of Orc4p binds to replication origin DNA via multiple AT-hooks. Proceedings of the National Academy of Sciences of the United States of America. 96: 2656-61. PMID 10077566 DOI: 10.1073/Pnas.96.6.2656  0.428
1998 Brown GW, Kelly TJ. Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast. The Journal of Biological Chemistry. 273: 22083-90. PMID 9705352 DOI: 10.1074/Jbc.273.34.22083  0.548
1998 Jallepalli PV, Tien D, Kelly TJ. sud1(+) targets cyclin-dependent kinase-phosphorylated Cdc18 and Rum1 proteins for degradation and stops unwanted diploidization in fission yeast. Proceedings of the National Academy of Sciences of the United States of America. 95: 8159-64. PMID 9653157 DOI: 10.1073/Pnas.95.14.8159  0.404
1997 Jallepalli PV, Brown GW, Muzi-Falconi M, Tien D, Kelly TJ. Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation. Genes & Development. 11: 2767-79. PMID 9353247 DOI: 10.1101/Gad.11.21.2767  0.604
1997 Brown GW, Jallepalli PV, Huneycutt BJ, Kelly TJ. Interaction of the S phase regulator cdc18 with cyclin-dependent kinase in fission yeast. Proceedings of the National Academy of Sciences of the United States of America. 94: 6142-7. PMID 9177184 DOI: 10.1073/Pnas.94.12.6142  0.576
1997 Parker AE, Clyne RK, Carr AM, Kelly TJ. The Schizosaccharomyces pombe rad11+ gene encodes the large subunit of replication protein A. Molecular and Cellular Biology. 17: 2381-90. PMID 9111307  0.371
1996 Brush GS, Morrow DM, Hieter P, Kelly TJ. The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast. Proceedings of the National Academy of Sciences of the United States of America. 93: 15075-80. PMID 8986766 DOI: 10.1073/Pnas.93.26.15075  0.347
1996 Ohtani K, DeGregori J, Leone G, Herendeen DR, Kelly TJ, Nevins JR. Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor. Molecular and Cellular Biology. 16: 6977-84. PMID 8943353 DOI: 10.1128/Mcb.16.12.6977  0.32
1996 Muzi-Falconi M, Brown GW, Kelly TJ. Controlling initiation during the cell cycle. DNA replication. Current Biology : Cb. 6: 229-33. PMID 8805233 DOI: 10.1016/S0960-9822(02)00464-5  0.573
1996 Muzi Falconi M, Brown GW, Kelly TJ. cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe. Proceedings of the National Academy of Sciences of the United States of America. 93: 1566-70. PMID 8643672 DOI: 10.1073/Pnas.93.4.1566  0.63
1996 Jallepalli PV, Kelly TJ. Rum1 and Cdc18 link inhibition of cyclin-dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe. Genes & Development. 10: 541-52. PMID 8598285 DOI: 10.1101/gad.10.5.541  0.339
1995 Muzi-Falconi M, Kelly TJ. Orp1, a member of the Cdc18/Cdc6 family of S-phase regulators, is homologous to a component of the origin recognition complex. Proceedings of the National Academy of Sciences of the United States of America. 92: 12475-9. PMID 8618924 DOI: 10.1073/Pnas.92.26.12475  0.379
1995 Brush GS, Kelly TJ, Stillman B. Identification of eukaryotic DNA replication proteins using simian virus 40 in vitro replication system. Methods in Enzymology. 262: 522-48. PMID 8594377 DOI: 10.1016/0076-6879(95)62043-5  0.357
1994 Brush GS, Anderson CW, Kelly TJ. The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication. Proceedings of the National Academy of Sciences of the United States of America. 91: 12520-4. PMID 7809070 DOI: 10.1073/Pnas.91.26.12520  0.374
1993 Collins KL, Russo AA, Tseng BY, Kelly TJ. The role of the 70 kDa subunit of human DNA polymerase alpha in DNA replication. The Embo Journal. 12: 4555-66. PMID 8223465  0.31
1993 Kelly TJ, Nurse P, Forsburg SL. Coupling DNA replication to the cell cycle. Cold Spring Harbor Symposia On Quantitative Biology. 58: 637-44. PMID 7956080  0.309
1992 Cheng LZ, Workman JL, Kingston RE, Kelly TJ. Regulation of DNA replication in vitro by the transcriptional activation domain of GAL4-VP16. Proceedings of the National Academy of Sciences of the United States of America. 89: 589-93. PMID 1309949 DOI: 10.1073/Pnas.89.2.589  0.425
1991 Erdile LF, Heyer WD, Kolodner R, Kelly TJ. Characterization of a cDNA encoding the 70-kDa single-stranded DNA-binding subunit of human replication protein A and the role of the protein in DNA replication. The Journal of Biological Chemistry. 266: 12090-8. PMID 2050703  0.305
1991 Moore SP, Erdile L, Kelly T, Fishel R. The human homologous pairing protein HPP-1 is specifically stimulated by the cognate single-stranded binding protein hRP-A Proceedings of the National Academy of Sciences of the United States of America. 88: 9067-9071. PMID 1924369 DOI: 10.1073/Pnas.88.20.9067  0.372
1991 Temperley SM, Burrow CR, Kelly TJ, Hay RT. Identification of two distinct regions within the adenovirus minimal origin of replication that are required for adenovirus type 4 DNA replication in vitro. Journal of Virology. 65: 5037-44. PMID 1870210  0.325
1990 Heyer WD, Rao MR, Erdile LF, Kelly TJ, Kolodner RD. An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A. The Embo Journal. 9: 2321-9. PMID 2192864 DOI: 10.1002/J.1460-2075.1990.Tb07404.X  0.353
1990 Weinberg DH, Collins KL, Simancek P, Russo A, Wold MS, Virshup DM, Kelly TJ. Reconstitution of simian virus 40 DNA replication with purified proteins. Proceedings of the National Academy of Sciences of the United States of America. 87: 8692-6. PMID 2174160 DOI: 10.1073/Pnas.87.22.8692  0.335
1989 Weinberg DH, Kelly TJ. Requirement for two DNA polymerases in the replication of simian virus 40 DNA in vitro. Proceedings of the National Academy of Sciences of the United States of America. 86: 9742-6. PMID 2574863 DOI: 10.1073/Pnas.86.24.9742  0.441
1989 Kelly TJ. DNA replication in mammalian cells: insights from the SV40 model system. Harvey Lectures. 85: 173-88. PMID 2562399  0.326
1989 Virshup DM, Kauffman MG, Kelly TJ. Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2A. The Embo Journal. 8: 3891-8. PMID 2555176 DOI: 10.1002/J.1460-2075.1989.Tb08568.X  0.342
1989 Virshup DM, Kelly TJ. Purification of replication protein C, a cellular protein involved in the initial stages of simian virus 40 DNA replication in vitro. Proceedings of the National Academy of Sciences of the United States of America. 86: 3584-8. PMID 2542940 DOI: 10.1073/Pnas.86.10.3584  0.432
1989 Wold MS, Weinberg DH, Virshup DM, Li JJ, Kelly TJ. Identification of cellular proteins required for simian virus 40 DNA replication. The Journal of Biological Chemistry. 264: 2801-9. PMID 2536723  0.344
1989 Mueller SC, Kelly T, Dai MZ, Dai HN, Chen WT. Dynamic cytoskeleton-integrin associations induced by cell binding to immobilized fibronectin. The Journal of Cell Biology. 109: 3455-64. PMID 2513332 DOI: 10.1083/Jcb.109.6.3455  0.328
1988 Wold MS, Kelly T. Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA. Proceedings of the National Academy of Sciences of the United States of America. 85: 2523-7. PMID 2833742 DOI: 10.1073/Pnas.85.8.2523  0.346
1988 O'Neill EA, Kelly TJ. Purification and characterization of nuclear factor III (origin recognition protein C), a sequence-specific DNA binding protein required for efficient initiation of adenovirus DNA replication Journal of Biological Chemistry. 263: 931-937. PMID 2826468  0.301
1987 Rosenfeld PJ, O'Neill EA, Wides RJ, Kelly TJ. Sequence-specific interactions between cellular DNA-binding proteins and the adenovirus origin of DNA replication Molecular and Cellular Biology. 7: 875-886. PMID 3821731 DOI: 10.1128/mcb.7.2.875-886.1987  0.333
1987 Wides RJ, Challberg MD, Rawlins DR, Kelly TJ. Adenovirus origin of DNA replication: Sequence requirements for replication in vitro Molecular and Cellular Biology. 7: 864-874. PMID 3821730 DOI: 10.1128/mcb.7.2.864-874.1987  0.345
1987 Burridge K, Molony L, Kelly T. Adhesion plaques: sites of transmembrane interaction between the extracellular matrix and the actin cytoskeleton. Journal of Cell Science. 8: 211-229. PMID 3332661 DOI: 10.1242/Jcs.1987.Supplement_8.12  0.305
1987 Wold MS, Li JJ, Kelly TJ. Initiation of simian virus 40 DNA replication in vitro: large-tumor-antigen- and origin-dependent unwinding of the template. Proceedings of the National Academy of Sciences of the United States of America. 84: 3643-7. PMID 3035543 DOI: 10.1073/Pnas.84.11.3643  0.324
1987 Yang L, Wold MS, Li JJ, Kelly TJ, Liu LF. Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro. Proceedings of the National Academy of Sciences of the United States of America. 84: 950-4. PMID 3029765 DOI: 10.1073/Pnas.84.4.950  0.43
1987 Jones KA, Kadonaga JT, Rosenfeld PJ, Kelly TJ, Tjian R. A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication. Cell. 48: 79-89. PMID 3024847 DOI: 10.1016/0092-8674(87)90358-8  0.308
1987 Kelly TJ, Rosenfeld PJ, Wides RJ, O'Neill EA, Li JJ, Wold MS. Replication of adenovirus and SV40 chromosomes in vitro. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 317: 429-38. PMID 2894680 DOI: 10.1098/Rstb.1987.0070  0.348
1986 Kreidberg JA, Kelly TJ. Genetic analysis of the human thymidine kinase gene promoter. Molecular and Cellular Biology. 6: 2903-9. PMID 3785218 DOI: 10.1128/mcb.6.8.2903-2909.1986  0.608
1986 Li JJ, Peden KWC, Dixon RAF, Kelly T. Functional organization of the Simian virus 40 origin of DNA replication Molecular and Cellular Biology. 6: 1117-1128. PMID 3023870 DOI: 10.1128/mcb.6.4.1117-1128.1986  0.42
1985 Li JJ, Kelly TJ. Simian virus 40 DNA replication in vitro. Proceedings of the National Academy of Sciences of the United States of America. 81: 6973-7. PMID 6095264 DOI: 10.1073/PNAS.81.22.6973  0.319
1985 Li JJ, Kelly TJ. Simian virus 40 DNA replication in vitro: Specificity of initiation and evidence for bidirectional replication Molecular and Cellular Biology. 5: 1238-1246. PMID 2993858 DOI: 10.1128/Mcb.5.6.1238  0.444
1984 Rawlins DR, Rosenfeld PJ, Wides RJ, Challberg MD, Kelly TJ. Structure and function of the adenovirus origin of replication Cell. 37: 309-319. PMID 6722875 DOI: 10.1016/0092-8674(84)90327-1  0.316
1983 Ostrove JM, Rosenfeld P, Williams J, Kelly TJ. In vitro complementation as an assay for purification of adenovirus DNA replication proteins. Proceedings of the National Academy of Sciences of the United States of America. 80: 935-9. PMID 6573663 DOI: 10.1073/pnas.80.4.935  0.343
1982 Challberg MD, Ostrove JM, Kelly TJ. Initiation of adenovirus DNA replication: detection of covalent complexes between nucleotide and the 80-kilodalton terminal protein. Journal of Virology. 41: 265-70. PMID 6896346 DOI: 10.1128/JVI.41.1.265-270.1982  0.319
1980 Challberg MD, Desiderio SV, Kelly TJ. Adenovirus DNA replication in vitro: characterization of a protein covalently linked to nascent DNA strands. Proceedings of the National Academy of Sciences of the United States of America. 77: 5105-9. PMID 6933548 DOI: 10.1073/Pnas.77.9.5105  0.313
1976 Ketner G, Kelly TJ. Integrated simian virus 40 sequences in transformed cell DNA: analysis using restriction endonucleases Proceedings of the National Academy of Sciences of the United States of America. 73: 1102-1106. PMID 177975 DOI: 10.1073/Pnas.73.4.1102  0.407
1974 Smith HO, Kelly TJ, Roy PH. Enzymatic methods for sequence analysis applied to DNA restriction and methylation sites. Methods in Enzymology. 29: 282-94. PMID 4368687 DOI: 10.1016/0076-6879(74)29028-1  0.536
1970 Kelly TJ, Smith HO. A restriction enzyme from Hemophilus influenzae. II. Journal of Molecular Biology. 51: 393-409. PMID 5312501 DOI: 10.1016/0022-2836(70)90150-6  0.408
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