Trevor Sharp - Publications

Affiliations: 
Pharmacology University of Oxford, Oxford, United Kingdom 
Area:
Depression, Schizophrenia, 5HT Signalling

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Collins HM, Gullino LS, Ozdemir D, Lazarenco C, Sudarikova Y, Daly E, Pilar Cuéllar F, Pinacho R, Bannerman DM, Sharp T. Rebound activation of 5-HT neurons following SSRI discontinuation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 38609530 DOI: 10.1038/s41386-024-01857-8  0.421
2024 Gullino LS, Fuller C, Dunn P, Collins HM, El Mestikawy S, Sharp T. Evidence for a Role of 5-HT-glutamate Co-releasing Neurons in Acute Stress Mechanisms. Acs Chemical Neuroscience. PMID 38377469 DOI: 10.1021/acschemneuro.3c00758  0.384
2024 Ocana-Santero G, Packer AM, Sharp T, Butt SJB. Two-Photon Microscopy Reveals Sensory-Evoked Serotonin (5-HT) Release in Adult Mammalian Neocortex. Acs Chemical Neuroscience. PMID 38251903 DOI: 10.1021/acschemneuro.3c00725  0.374
2022 Schweimer JV, Brouard JT, Li Y, Sánchez C, Sharp T. In vivo electrophysiological study of the targeting of 5-HT receptor-expressing cortical interneurons by the multimodal antidepressant, vortioxetine. The European Journal of Neuroscience. PMID 35146812 DOI: 10.1111/ejn.15623  0.793
2021 Barnes NM, Ahern GP, Becamel C, Bockaert J, Camilleri M, Chaumont-Dubel S, Claeysen S, Cunningham KA, Fone KC, Gershon M, Di Giovanni G, Goodfellow NM, Halberstadt AL, Hartley RM, Hassaine G, ... ... Sharp T, et al. International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function. Pharmacological Reviews. 73: 310-520. PMID 33370241 DOI: 10.1124/pr.118.015552  0.314
2020 Sharp T, Barnes NM. Central 5-HT receptors and their function; present and future. Neuropharmacology. 108155. PMID 32522572 DOI: 10.1016/J.Neuropharm.2020.108155  0.492
2020 Joshi A, Wang DH, Watterson S, McClean PL, Behera CK, Sharp T, Wong-Lin K. Opportunities for multiscale computational modelling of serotonergic drug effects in Alzheimer's disease. Neuropharmacology. 108118. PMID 32380022 DOI: 10.1016/J.Neuropharm.2020.108118  0.337
2018 Matrov D, Kaart T, Lanfumey L, Maldonado R, Sharp T, Tordera RM, Kelly PA, Deakin B, Harro J. Cerebral oxidative metabolism mapping in four genetic mouse models of anxiety and mood disorders. Behavioural Brain Research. PMID 29885846 DOI: 10.1016/J.Bbr.2018.05.031  0.309
2018 Antoniadou I, Kouskou M, Arsiwala T, Singh N, Vasudevan SR, Fowler T, Cadirci E, Churchill GC, Sharp T. Ebselen has lithium-like effects on central 5-HTreceptor function. British Journal of Pharmacology. PMID 29488218 DOI: 10.1111/Bph.14179  0.31
2017 Heckman PRA, Schweimer JV, Sharp T, Prickaerts J, Blokland A. Phosphodiesterase 4 inhibition affects both the direct and indirect pathway: an electrophysiological study examining the tri-phasic response in the substantia nigra pars reticulata. Brain Structure & Function. 223: 739-748. PMID 28924693 DOI: 10.1007/S00429-017-1518-8  0.749
2017 Adams WK, Barkus C, Ferland JN, Sharp T, Winstanley CA. Pharmacological evidence that 5-HT2C receptor blockade selectively improves decision making when rewards are paired with audiovisual cues in a rat gambling task. Psychopharmacology. PMID 28733811 DOI: 10.1007/S00213-017-4696-4  0.321
2017 Sengupta A, Bocchio M, Bannerman DM, Sharp T, Capogna M. Control of amygdala circuits by 5-HT neurons via 5-HT and glutamate co-transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28087766 DOI: 10.1523/Jneurosci.2238-16.2016  0.521
2016 Hartung H, Tan SK, Temel Y, Sharp T. High frequency stimulation of the subthalamic nucleus modulates neuronal activity in the lateral habenula nucleus. The European Journal of Neuroscience. PMID 27623306 DOI: 10.1111/Ejn.13397  0.386
2016 Barkus C, Korn C, Stumpenhorst K, Laatikainen LM, Ballard D, Lee S, Sharp T, Harrison PJ, Bannerman DM, Weinberger DR, Chen J, Tunbridge EM. Genotype-Dependent Effects of COMT Inhibition on Cognitive Function in a Highly-Specific, Novel Mouse Model of Altered COMT Activity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27388330 DOI: 10.1038/Npp.2016.119  0.451
2016 Bocchio M, McHugh SB, Bannerman DM, Sharp T, Capogna M. Serotonin, Amygdala and Fear: Assembling the Puzzle. Frontiers in Neural Circuits. 10: 24. PMID 27092057 DOI: 10.3389/Fncir.2016.00024  0.487
2016 Pritchett D, Taylor AM, Barkus C, Engle SJ, Brandon NJ, Sharp T, Foster RG, Harrison PJ, Peirson SN, Bannerman DM. Searching for cognitive enhancement in the Morris watermaze: Better and worse performance in D-amino acid oxidase knockout (Dao(-/-) ) mice. The European Journal of Neuroscience. PMID 26833794 DOI: 10.1111/Ejn.13192  0.434
2015 Hescham S, Jahanshahi A, Schweimer JV, Mitchell SN, Carter G, Blokland A, Sharp T, Temel Y. Fornix deep brain stimulation enhances acetylcholine levels in the hippocampus. Brain Structure & Function. PMID 26597361 DOI: 10.1007/S00429-015-1144-2  0.744
2015 Spain A, Howarth C, Khrapitchev AA, Sharp T, Sibson NR, Martin C. Neurovascular and neuroimaging effects of the hallucinogenic serotonin receptor agonist psilocin in the rat brain. Neuropharmacology. 99: 210-220. PMID 26192543 DOI: 10.1016/J.Neuropharm.2015.07.018  0.383
2015 Couch Y, Xie Q, Lundberg L, Sharp T, Anthony DC. A Model of Post-Infection Fatigue Is Associated with Increased TNF and 5-HT2A Receptor Expression in Mice. Plos One. 10: e0130643. PMID 26147001 DOI: 10.1371/Journal.Pone.0130643  0.774
2015 Bocchio M, Fucsina G, Oikonomidis L, McHugh SB, Bannerman DM, Sharp T, Capogna M. Increased Serotonin Transporter Expression Reduces Fear and Recruitment of Parvalbumin Interneurons of the Amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26052039 DOI: 10.1038/Npp.2015.157  0.457
2015 Brouard JT, Schweimer JV, Houlton R, Burnham KE, Quérée P, Sharp T. Pharmacological Evidence for 5-HT6 Receptor Modulation of 5-HT Neuron Firing in Vivo. Acs Chemical Neuroscience. 6: 1241-7. PMID 25837696 DOI: 10.1021/Acschemneuro.5B00061  0.809
2015 Lim LW, Prickaerts J, Huguet G, Kadar E, Hartung H, Sharp T, Temel Y. Electrical stimulation alleviates depressive-like behaviors of rats: investigation of brain targets and potential mechanisms. Translational Psychiatry. 5: e535. PMID 25826110 DOI: 10.1038/Tp.2015.24  0.346
2015 Pritchett D, Hasan S, Tam SK, Engle SJ, Brandon NJ, Sharp T, Foster RG, Harrison PJ, Bannerman DM, Peirson SN. d-amino acid oxidase knockout (Dao(-/-) ) mice show enhanced short-term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption. The European Journal of Neuroscience. 41: 1167-79. PMID 25816902 DOI: 10.1111/Ejn.12880  0.431
2014 Couch Y, Martin CJ, Howarth C, Raley J, Khrapitchev AA, Stratford M, Sharp T, Sibson NR, Anthony DC. Corrigendum to "Systemic inflammation alters central 5-HT function as determined by pharmacological MRI" [Neuroimage 75 (2013) 177-186]. Neuroimage. 94: 413. PMID 28843644 DOI: 10.1016/J.Neuroimage.2014.03.021  0.755
2014 Line SJ, Barkus C, Rawlings N, Jennings K, McHugh S, Sharp T, Bannerman DM. Reduced sensitivity to both positive and negative reinforcement in mice over-expressing the 5-hydroxytryptamine transporter. The European Journal of Neuroscience. 40: 3735-45. PMID 25283165 DOI: 10.1111/Ejn.12744  0.327
2014 Schweimer JV, Coullon GS, Betts JF, Burnet PW, Engle SJ, Brandon NJ, Harrison PJ, Sharp T. Increased burst-firing of ventral tegmental area dopaminergic neurons in D-amino acid oxidase knockout mice in vivo. The European Journal of Neuroscience. 40: 2999-3009. PMID 25040393 DOI: 10.1111/Ejn.12667  0.773
2014 Betts JF, Schweimer JV, Burnham KE, Burnet PW, Sharp T, Harrison PJ. D-amino acid oxidase is expressed in the ventral tegmental area and modulates cortical dopamine. Frontiers in Synaptic Neuroscience. 6: 11. PMID 24822045 DOI: 10.3389/Fnsyn.2014.00011  0.768
2014 Barkus C, Line SJ, Huber A, Capitao L, Lima J, Jennings K, Lowry J, Sharp T, Bannerman DM, McHugh SB. Variation in serotonin transporter expression modulates fear-evoked hemodynamic responses and theta-frequency neuronal oscillations in the amygdala. Biological Psychiatry. 75: 901-8. PMID 24120093 DOI: 10.1016/J.Biopsych.2013.09.003  0.334
2014 Couch Y, Martin CJ, Howarth C, Raley J, Khrapitchev AA, Stratford M, Sharp T, Sibson NR, Anthony DC. Corrigendum to "Systemic inflammation alters central 5-HT function as determined by pharmacological MRI" [Neuroimage 75 (2013) 177-186] Neuroimage. 94: 413. DOI: 10.1016/j.neuroimage.2014.03.021  0.742
2013 Le Masurier M, Zetterström T, Cowen P, Sharp T. Tyrosine-free amino acid mixtures reduce physiologically-evoked release of dopamine in a selective and activity-dependent manner. Journal of Psychopharmacology (Oxford, England). 28: 561-569. PMID 24108408 DOI: 10.1177/0269881113507642  0.326
2013 Lane TA, Boerner T, Bannerman DM, Kew JN, Tunbridge EM, Sharp T, Harrison PJ. Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice. Bmc Neuroscience. 14: 102. PMID 24053122 DOI: 10.1186/1471-2202-14-102  0.502
2013 Laatikainen LM, Sharp T, Harrison PJ, Tunbridge EM. Sexually dimorphic effects of catechol-O-methyltransferase (COMT) inhibition on dopamine metabolism in multiple brain regions. Plos One. 8: e61839. PMID 23613951 DOI: 10.1371/Journal.Pone.0061839  0.461
2013 Couch Y, Martin CJ, Howarth C, Raley J, Khrapitchev AA, Stratford M, Sharp T, Sibson NR, Anthony DC. Systemic inflammation alters central 5-HT function as determined by pharmacological MRI. Neuroimage. 75: 177-86. PMID 23473937 DOI: 10.1016/J.Neuroimage.2013.02.046  0.781
2013 Antoniadou I, Fowler T, Cardici E, Arsiwala T, Sharp T. P.2.c.013 Effect of the putative lithium-mimetic ebselen on 5-HT neurochemistry in the mouse brain European Neuropsychopharmacology. 23: S362. DOI: 10.1016/S0924-977X(13)70571-6  0.302
2012 Serres F, Rodriguez M, Rivet JM, Galizzi JP, Lockhart B, Sharp T, Millan MJ. Blockade of α2-adrenoceptors induces Arc gene expression in rat brain in a glutamate receptor-dependent manner: a combined qPCR, in situ hybridisation and immunocytochemistry study. Neuropharmacology. 63: 992-1001. PMID 22828637 DOI: 10.1016/J.Neuropharm.2012.06.068  0.394
2012 Laatikainen LM, Sharp T, Bannerman DM, Harrison PJ, Tunbridge EM. Modulation of hippocampal dopamine metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition. Journal of Psychopharmacology (Oxford, England). 26: 1561-8. PMID 22815336 DOI: 10.1177/0269881112454228  0.474
2012 Dekeyne A, Brocco M, Loiseau F, Gobert A, Rivet JM, Di Cara B, Cremers TI, Flik G, Fone KC, Watson DJ, Papp M, Sharp T, Serres F, Cespuglio R, Olivier B, et al. S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: II. A behavioral, neurochemical, and electrophysiological characterization. The Journal of Pharmacology and Experimental Therapeutics. 340: 765-80. PMID 22178753 DOI: 10.1124/Jpet.111.187534  0.438
2012 Hafizi S, Serres F, Pei Q, Totterdell S, Sharp T. Evidence for the differential co-localization of neurokinin-1 receptors with 5-HT receptor subtypes in rat forebrain. Journal of Psychopharmacology (Oxford, England). 26: 505-15. PMID 22057017 DOI: 10.1177/0269881111425969  0.465
2012 Tan SK, Hartung H, Visser-Vandewalle V, Steinbusch HW, Temel Y, Sharp T. A combined in vivo neurochemical and electrophysiological analysis of the effect of high-frequency stimulation of the subthalamic nucleus on 5-HT transmission. Experimental Neurology. 233: 145-53. PMID 21925498 DOI: 10.1016/J.Expneurol.2011.08.027  0.521
2012 Harrison PJ, Pritchett D, Stumpenhorst K, Betts JF, Nissen W, Schweimer J, Lane T, Burnet PW, Lamsa KP, Sharp T, Bannerman DM, Tunbridge EM. Genetic mouse models relevant to schizophrenia: taking stock and looking forward. Neuropharmacology. 62: 1164-7. PMID 21864547 DOI: 10.1016/J.Neuropharm.2011.08.009  0.737
2012 Jennings KA, Licht CL, Bruce A, Lesch KP, Knudsen GM, Sharp T. Genetic variation in 5-hydroxytryptamine transporter expression causes adaptive changes in 5-HTâ‚„ receptor levels. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1099-107. PMID 21846421 DOI: 10.1017/S1461145711001258  0.487
2012 Serres F, Millan MJ, Sharp T. Molecular adaptation to chronic antidepressant treatment: evidence for a more rapid response to the novel α₂-adrenoceptor antagonist/5-HT-noradrenaline reuptake inhibitor (SNRI), S35966, compared to the SNRI, venlafaxine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 617-29. PMID 21733241 DOI: 10.1017/S1461145711000733  0.383
2011 Schweimer JV, Mallet N, Sharp T, Ungless MA. Spike-timing relationship of neurochemically-identified dorsal raphe neurons during cortical slow oscillations. Neuroscience. 196: 115-23. PMID 21925244 DOI: 10.1016/J.Neuroscience.2011.08.072  0.766
2011 Tan SK, Janssen ML, Jahanshahi A, Chouliaras L, Visser-Vandewalle V, Lim LW, Steinbusch HW, Sharp T, Temel Y. High frequency stimulation of the subthalamic nucleus increases c-fos immunoreactivity in the dorsal raphe nucleus and afferent brain regions. Journal of Psychiatric Research. 45: 1307-15. PMID 21641003 DOI: 10.1016/J.Jpsychires.2011.04.011  0.435
2011 Hartung H, Tan SK, Steinbusch HM, Temel Y, Sharp T. High-frequency stimulation of the subthalamic nucleus inhibits the firing of juxtacellular labelled 5-HT-containing neurones. Neuroscience. 186: 135-45. PMID 21515342 DOI: 10.1016/J.Neuroscience.2011.04.004  0.469
2011 Sharp T, Cowen PJ. 5-HT and depression: is the glass half-full? Current Opinion in Pharmacology. 11: 45-51. PMID 21377932 DOI: 10.1016/J.Coph.2011.02.003  0.412
2011 Tan SK, Hartung H, Sharp T, Temel Y. Serotonin-dependent depression in Parkinson's disease: a role for the subthalamic nucleus? Neuropharmacology. 61: 387-99. PMID 21251918 DOI: 10.1016/J.Neuropharm.2011.01.006  0.421
2011 Line SJ, Barkus C, Coyle C, Jennings KA, Deacon RM, Lesch KP, Sharp T, Bannerman DM. Opposing alterations in anxiety and species-typical behaviours in serotonin transporter overexpressor and knockout mice. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 21: 108-16. PMID 20863670 DOI: 10.1016/J.Euroneuro.2010.08.005  0.305
2011 Laatikainen L, Sharp T, Harrison P, Tunbridge E. P.4.002 Catechol-o-methyltransferase (COMT) influences dopamine metabolism outside of the prefrontal cortex European Neuropsychopharmacology. 21: S79-S80. DOI: 10.1016/S0924-977X(11)70091-8  0.405
2010 Jennings KA, Lesch KP, Sharp T, Cragg SJ. Non-linear relationship between 5-HT transporter gene expression and frequency sensitivity of 5-HT signals. Journal of Neurochemistry. 115: 965-73. PMID 20854367 DOI: 10.1111/j.1471-4159.2010.07001.x  0.351
2010 Licht CL, Knudsen GM, Sharp T. Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels. Neuroscience Letters. 476: 58-61. PMID 20381585 DOI: 10.1016/j.neulet.2010.04.002  0.392
2010 Burnham KE, Baxter MG, Bainton JR, Southam E, Dawson LA, Bannerman DM, Sharp T. Activation of 5-HT(6) receptors facilitates attentional set shifting. Psychopharmacology. 208: 13-21. PMID 19902184 DOI: 10.1007/s00213-009-1701-6  0.376
2010 Couch Y, Xie Q, Martin C, Raley J, Davies A, Sibson N, Sharp T, Anthony D. Infection-associated changes in 5-HT function Brain, Behavior, and Immunity. 24: S17. DOI: 10.1016/J.Bbi.2010.07.054  0.744
2009 Quérée P, Peters S, Sharp T. Further pharmacological characterization of 5-HT(2C) receptor agonist-induced inhibition of 5-HT neuronal activity in the dorsal raphe nucleus in vivo. British Journal of Pharmacology. 158: 1477-85. PMID 19845681 DOI: 10.1111/J.1476-5381.2009.00406.X  0.522
2009 Preece MA, Taylor MJ, Raley J, Blamire A, Sharp T, Sibson NR. Evidence that increased 5-HT release evokes region-specific effects on blood-oxygenation level-dependent functional magnetic resonance imaging responses in the rat brain. Neuroscience. 159: 751-9. PMID 19174180 DOI: 10.1016/J.Neuroscience.2008.12.032  0.39
2009 Sharp T, Hartung H, Tan S, Magill P, Blokland A, Visse-Vandevalle V, Steinbusch H, Temel Y. S.02.02 Mood effects of DBS of the subthalamic nucleus: a role for 5-HT European Neuropsychopharmacology. 19: S177. DOI: 10.1016/S0924-977X(09)70196-8  0.457
2008 Kaya AH, Vlamings R, Tan S, Lim LW, Magill PJ, Steinbusch HW, Visser-Vandewalle V, Sharp T, Temel Y. Increased electrical and metabolic activity in the dorsal raphe nucleus of Parkinsonian rats. Brain Research. 1221: 93-7. PMID 18565496 DOI: 10.1016/j.brainres.2008.05.019  0.372
2008 Dekeyne A, Mannoury la Cour C, Gobert A, Brocco M, Lejeune F, Serres F, Sharp T, Daszuta A, Soumier A, Papp M, Rivet JM, Flik G, Cremers TI, Muller O, Lavielle G, et al. S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models. Psychopharmacology. 199: 549-68. PMID 18523738 DOI: 10.1007/s00213-008-1177-9  0.394
2008 Jennings KA, Sheward WJ, Harmar AJ, Sharp T. Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function. Neuropharmacology. 54: 776-83. PMID 18241894 DOI: 10.1016/j.neuropharm.2007.12.001  0.399
2007 Sharp T, Boothman L, Raley J, Quérée P. Important messages in the 'post': recent discoveries in 5-HT neurone feedback control. Trends in Pharmacological Sciences. 28: 629-36. PMID 17996955 DOI: 10.1016/j.tips.2007.10.009  0.406
2007 Temel Y, Boothman LJ, Blokland A, Magill PJ, Steinbusch HW, Visser-Vandewalle V, Sharp T. Inhibition of 5-HT neuron activity and induction of depressive-like behavior by high-frequency stimulation of the subthalamic nucleus. Proceedings of the National Academy of Sciences of the United States of America. 104: 17087-92. PMID 17942692 DOI: 10.1073/pnas.0704144104  0.351
2007 Hughes ZA, Starr KR, Scott CM, Newson MJ, Sharp T, Watson JM, Hagan JJ, Dawson LA. Simultaneous blockade of 5-HT1A/B receptors and 5-HT transporters results in acute increases in extracellular 5-HT in both rats and guinea pigs: in vivo characterization of the novel 5-HT1A/B receptor antagonist/5-HT transport inhibitor SB-649915-B. Psychopharmacology. 192: 121-33. PMID 17265079 DOI: 10.1007/S00213-006-0691-X  0.494
2007 Stark AD, Jordan S, Allers KA, Bertekap RL, Chen R, Mistry Kannan T, Molski TF, Yocca FD, Sharp T, Kikuchi T, Burris KD. Interaction of the novel antipsychotic aripiprazole with 5-HT1A and 5-HT 2A receptors: functional receptor-binding and in vivo electrophysiological studies. Psychopharmacology. 190: 373-82. PMID 17242925 DOI: 10.1007/S00213-006-0621-Y  0.488
2007 Hajós M, Allers KA, Jennings K, Sharp T, Charette G, Sík A, Kocsis B. Neurochemical identification of stereotypic burst-firing neurons in the rat dorsal raphe nucleus using juxtacellular labelling methods. The European Journal of Neuroscience. 25: 119-26. PMID 17241273 DOI: 10.1111/J.1460-9568.2006.05276.X  0.484
2006 Boothman L, Raley J, Denk F, Hirani E, Sharp T. In vivo evidence that 5-HT(2C) receptors inhibit 5-HT neuronal activity via a GABAergic mechanism. British Journal of Pharmacology. 149: 861-9. PMID 17043669 DOI: 10.1038/Sj.Bjp.0706935  0.515
2006 Jennings KA, Loder MK, Sheward WJ, Pei Q, Deacon RM, Benson MA, Olverman HJ, Hastie ND, Harmar AJ, Shen S, Sharp T. Increased expression of the 5-HT transporter confers a low-anxiety phenotype linked to decreased 5-HT transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8955-64. PMID 16943551 DOI: 10.1523/Jneurosci.5356-05.2006  0.447
2006 Boothman LJ, Mitchell SN, Sharp T. Investigation of the SSRI augmentation properties of 5-HT(2) receptor antagonists using in vivo microdialysis. Neuropharmacology. 50: 726-32. PMID 16434063 DOI: 10.1016/J.Neuropharm.2005.11.020  0.494
2006 Sharp T. Neuroscience. A new molecule to brighten the mood. Science (New York, N.Y.). 311: 45-6. PMID 16400139 DOI: 10.1126/Science.1122819  0.365
2006 Serres F, Sartori SB, Halton A, Pei Q, Rochat C, Singewald N, Sharp T, Millan MJ, Millan M. Stereoselective and region-specific induction of immediate early gene expression in rat parietal cortex by blockade of neurokinin 1 receptors. Journal of Psychopharmacology (Oxford, England). 20: 570-6. PMID 16204322 DOI: 10.1177/0269881105059327  0.346
2006 Le Masurier M, Oldenzeil W, Lehman C, Cowen P, Sharp T. Effect of acute tyrosine depletion in using a branched chain amino-acid mixture on dopamine neurotransmission in the rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 310-7. PMID 16034439 DOI: 10.1038/Sj.Npp.1300835  0.309
2005 Tordera RM, Pei Q, Sharp T. Evidence for increased expression of the vesicular glutamate transporter, VGLUT1, by a course of antidepressant treatment. Journal of Neurochemistry. 94: 875-83. PMID 15992385 DOI: 10.1111/J.1471-4159.2005.03192.X  0.307
2005 Boothman LJ, Sharp T. A role for midbrain raphe gamma aminobutyric acid neurons in 5-hydroxytryptamine feedback control. Neuroreport. 16: 891-6. PMID 15931057 DOI: 10.1097/00001756-200506210-00004  0.507
2005 Austin VC, Blamire AM, Allers KA, Sharp T, Styles P, Matthews PM, Sibson NR. Confounding effects of anesthesia on functional activation in rodent brain: a study of halothane and alpha-chloralose anesthesia. Neuroimage. 24: 92-100. PMID 15588600 DOI: 10.1016/J.Neuroimage.2004.08.011  0.302
2004 Pei Q, Sprakes M, Millan MJ, Rochat C, Sharp T. The novel monoamine reuptake inhibitor and potential antidepressant, S33005, induces Arc gene expression in cerebral cortex. European Journal of Pharmacology. 495: 227-33. PMID 15838995 DOI: 10.1016/J.Ejphar.2004.05.002  0.326
2004 Tunbridge EM, Bannerman DM, Sharp T, Harrison PJ. Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5331-5. PMID 15190105 DOI: 10.1523/Jneurosci.1124-04.2004  0.429
2004 Pei Q, Tordera R, Sprakes M, Sharp T. Glutamate receptor activation is involved in 5-HT2 agonist-induced Arc gene expression in the rat cortex. Neuropharmacology. 46: 331-9. PMID 14975688 DOI: 10.1016/j.neuropharm.2003.09.017  0.326
2003 Hirani E, Sharp T, Sprakes M, Grasby P, Hume S. Fenfluramine evokes 5-HT2A receptor-mediated responses but does not displace [11C]MDL 100907: small animal PET and gene expression studies. Synapse (New York, N.Y.). 50: 251-60. PMID 14515343 DOI: 10.1002/syn.10268  0.377
2003 Harris LW, Sharp T, Gartlon J, Jones DN, Harrison PJ. Long-term behavioural, molecular and morphological effects of neonatal NMDA receptor antagonism. The European Journal of Neuroscience. 18: 1706-10. PMID 14511349 DOI: 10.1046/J.1460-9568.2003.02902.X  0.402
2003 Boothman LJ, Allers KA, Rasmussen K, Sharp T. Evidence that central 5-HT2A and 5-HT2B/C receptors regulate 5-HT cell firing in the dorsal raphe nucleus of the anaesthetised rat. British Journal of Pharmacology. 139: 998-1004. PMID 12839874 DOI: 10.1038/sj.bjp.0705328  0.423
2003 Hajós M, Gartside SE, Varga V, Sharp T. In vivo inhibition of neuronal activity in the rat ventromedial prefrontal cortex by midbrain-raphe nuclei: role of 5-HT1A receptors. Neuropharmacology. 45: 72-81. PMID 12814660 DOI: 10.1016/S0028-3908(03)00139-4  0.385
2003 Castro E, Tordera RM, Hughes ZA, Pei Q, Sharp T. Use of Arc expression as a molecular marker of increased postsynaptic 5-HT function after SSRI/5-HT1A receptor antagonist co-administration. Journal of Neurochemistry. 85: 1480-7. PMID 12787067 DOI: 10.1046/j.1471-4159.2003.01782.x  0.389
2003 Tordera R, Pei Q, Newson M, Gray K, Sprakes M, Sharp T. Effect of different 5-HT1A receptor antagonists in combination with paroxetine on expression of the immediate-early gene Arc in rat brain. Neuropharmacology. 44: 893-902. PMID 12726821 DOI: 10.1016/S0028-3908(03)00096-0  0.369
2003 Varga V, Kocsis B, Sharp T. Electrophysiological evidence for convergence of inputs from the medial prefrontal cortex and lateral habenula on single neurons in the dorsal raphe nucleus. The European Journal of Neuroscience. 17: 280-6. PMID 12542664 DOI: 10.1046/j.1460-9568.2003.02465.x  0.392
2003 Grasby P, Hirani E, Hume S, Cowen P, Rabiner E, Sharp T. S.06.04 Can we measure 5-HT release with PET? European Neuropsychopharmacology. 13: S110. DOI: 10.1016/S0924-977X(03)91623-3  0.411
2003 Harris L, Sharp T, Harrison P. A neurodevelopmental, glutamatergic model relevant to schizophrenia? MK801-induced apoptosis in the neonatal rat produces molecular changes in the adult brain Schizophrenia Research. 60: 57-58. DOI: 10.1016/S0920-9964(03)80557-1  0.338
2002 Meller R, Harrison PJ, Sharp T. Studies on the role of calcium in the 5-HT-stimulated release of glutamate from C6 glioma cells. European Journal of Pharmacology. 445: 13-9. PMID 12065189 DOI: 10.1016/S0014-2999(02)01718-1  0.473
2002 Hajós-Korcsok E, Sharp T. Electrical stimulation of the dorsal and median raphe nuclei increases extracellular noradrenaline in rat hippocampus: Evidence for a 5-HT-independent mechanism. Pharmacology, Biochemistry, and Behavior. 71: 807-13. PMID 11888571 DOI: 10.1016/S0091-3057(01)00718-3  0.404
2002 Meller R, Harrison PJ, Elliott JM, Sharp T. In vitro evidence that 5-hydroxytryptamine increases efflux of glial glutamate via 5-HT(2A) receptor activation. Journal of Neuroscience Research. 67: 399-405. PMID 11813245 DOI: 10.1002/Jnr.10126  0.53
2001 Varga V, Székely AD, Csillag A, Sharp T, Hajós M. Evidence for a role of GABA interneurones in the cortical modulation of midbrain 5-hydroxytryptamine neurones. Neuroscience. 106: 783-92. PMID 11682163 DOI: 10.1016/S0306-4522(01)00294-9  0.364
2001 Hajós M, Hoffmann WE, Tetko IV, Hyland B, Sharp T, Villa AE. Different tonic regulation of neuronal activity in the rat dorsal raphe and medial prefrontal cortex via 5-HT(1A) receptors. Neuroscience Letters. 304: 129-32. PMID 11343819 DOI: 10.1016/S0304-3940(01)01751-7  0.51
2001 Burnet PW, Miller R, Lewis LJ, Pei Q, Sharp T, Harrison PJ. Electroconvulsive shock increases tachykinin NK(1) receptors, but not the encoding mRNA, in rat cortex. European Journal of Pharmacology. 413: 213-9. PMID 11226395 DOI: 10.1016/S0014-2999(01)00777-4  0.463
2000 Rabiner EA, Gunn RN, Castro ME, Sargent PA, Cowen PJ, Koepp MJ, Meyer JH, Bench CJ, Harrison PJ, Pazos A, Sharp T, Grasby PM. beta-blocker binding to human 5-HT(1A) receptors in vivo and in vitro: implications for antidepressant therapy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 285-93. PMID 10942852 DOI: 10.1016/S0893-133X(00)00109-3  0.544
2000 Engberg G, Erhardt S, Sharp T, Hajós M. Nicotine inhibits firing activity of dorsal raphe 5-HT neurones in vivo. Naunyn-Schmiedeberg's Archives of Pharmacology. 362: 41-5. PMID 10935531 DOI: 10.1007/S002100000252  0.346
2000 Castro ME, Harrison PJ, Pazos A, Sharp T. Affinity of (+/-)-pindolol, (-)-penbutolol, and (-)-tertatolol for pre- and postsynaptic serotonin 5-HT(1A) receptors in human and rat brain. Journal of Neurochemistry. 75: 755-62. PMID 10899952 DOI: 10.1046/J.1471-4159.2000.0750755.X  0.56
1999 Burnet PW, Sharp T, LeCorre SM, Harrison PJ. Expression of 5-HT receptors and the 5-HT transporter in rat brain after electroconvulsive shock. Neuroscience Letters. 277: 79-82. PMID 10624814 DOI: 10.1016/S0304-3940(99)00857-5  0.536
1999 Hajós-Korcsok E, Sharp T. Effect of 5-HT(1A) receptor ligands on Fos-like immunoreactivity in rat brain: evidence for activation of noradrenergic transmission. Synapse (New York, N.Y.). 34: 145-53. PMID 10502313 DOI: 10.1002/(Sici)1098-2396(199911)34:2<145::Aid-Syn7>3.0.Co;2-D  0.412
1999 Barnes NM, Sharp T. A review of central 5-HT receptors and their function. Neuropharmacology. 38: 1083-152. PMID 10462127  0.353
1999 Hajós M, Hajós-Korcsok E, Sharp T. Role of the medial prefrontal cortex in 5-HT1A receptor-induced inhibition of 5-HT neuronal activity in the rat. British Journal of Pharmacology. 126: 1741-50. PMID 10372816 DOI: 10.1038/Sj.Bjp.0702510  0.416
1999 Gartside SE, Clifford EM, Cowen PJ, Sharp T. Effects of (-)-tertatolol, (-)-penbutolol and (+/-)-pindolol in combination with paroxetine on presynaptic 5-HT function: an in vivo microdialysis and electrophysiological study. British Journal of Pharmacology. 127: 145-52. PMID 10369467 DOI: 10.1038/sj.bjp.0702546  0.373
1998 Clifford EM, Gartside SE, Umbers V, Cowen PJ, Hajós M, Sharp T. Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5-HT1A autoreceptor in vivo. British Journal of Pharmacology. 124: 206-12. PMID 9630361 DOI: 10.1038/Sj.Bjp.0701796  0.414
1997 Gartside SE, McQuade R, Sharp T. Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on 5-HT cell firing and release: comparison between dorsal and median raphe 5-HT systems. Neuropharmacology. 36: 1697-703. PMID 9517441 DOI: 10.1016/S0028-3908(97)00171-8  0.506
1997 Le Corre SM, Burnet PW, Meller R, Sharp T, Harrison PJ. Critical issues in the antisense inhibition of brain gene expression in vivo: experiences targetting the 5-HT1A receptor. Neurochemistry International. 31: 349-62. PMID 9246678 DOI: 10.1016/S0197-0186(96)00106-4  0.398
1997 McQuade R, Sharp T. Functional mapping of dorsal and median raphe 5-hydroxytryptamine pathways in forebrain of the rat using microdialysis. Journal of Neurochemistry. 69: 791-6. PMID 9231740 DOI: 10.1046/j.1471-4159.1997.69020791.x  0.372
1997 Sharp T, Umbers V, Gartside SE. Effect of a selective 5-HT reuptake inhibitor in combination with 5-HT1A and 5-HT1B receptor antagonists on extracellular 5-HT in rat frontal cortex in vivo. British Journal of Pharmacology. 121: 941-6. PMID 9222551 DOI: 10.1038/sj.bjp.0701235  0.403
1997 Hajós M, Sharp T. 5-HT neurones--bursting with information? Trends in Neurosciences. 20: 244. PMID 9185304 DOI: 10.1016/S0166-2236(97)86999-8  0.349
1997 Le Corre S, Sharp T, Young AH, Harrison PJ. Increase of 5-HT7 (serotonin-7) and 5-HT1A (serotonin-1A) receptor mRNA expression in rat hippocampus after adrenalectomy. Psychopharmacology. 130: 368-74. PMID 9160853 DOI: 10.1007/S002130050252  0.59
1997 Gartside SE, Umbers V, Sharp T. Inhibition of 5-HT cell firing in the DRN by non-selective 5-HT reuptake inhibitors: studies on the role of 5-HT1A autoreceptors and noradrenergic mechanisms. Psychopharmacology. 130: 261-8. PMID 9151361 DOI: 10.1007/S002130050238  0.49
1997 Sharp T, Gartside SE, Umbers V. Effects of co-administration of a monoamine oxidase inhibitor and a 5-HT1A receptor antagonist on 5-hydroxytryptamine cell firing and release. European Journal of Pharmacology. 320: 15-9. PMID 9049597 DOI: 10.1016/S0014-2999(96)00968-5  0.507
1997 Hajós M, Sharp T. Burst-firing activity of presumed 5-HT neurones of the rat dorsal raphe nucleus: electrophysiological analysis by antidromic stimulation. Brain Research. 740: 162-8. PMID 8973810 DOI: 10.1016/S0006-8993(96)00869-4  0.404
1997 Hajós-Korcsok E, Sharp T. 8-OH-DPAT-induced release of hippocampal noradrenaline in vivo: evidence for a role of both 5-HT1A and dopamine D1 receptors. European Journal of Pharmacology. 314: 285-91. PMID 8957248 DOI: 10.1016/S0014-2999(96)00560-2  0.392
1997 Hajos M, Sharp T. A 5-hydroxytryptamine lesion markedly reduces the incidence of burst-firing dorsal raphe neurones in the rat. Neuroscience Letters. 204: 161-4. PMID 8938255 DOI: 10.1016/0304-3940(96)12333-8  0.478
1997 Hajós M, Sharp T, Newberry NR. Intracellular recordings from burst-firing presumed serotonergic neurones in the rat dorsal raphe nucleus in vivo. Brain Research. 737: 308-12. PMID 8930381 DOI: 10.1016/0006-8993(96)00936-5  0.406
1996 Sharp T, Umbers V, Hjorth S. The role of 5-HT1A autoreceptors and alpha 1-adrenoceptors in the inhibition of 5-HT release--II NAN-190 and SDZ 216-525. Neuropharmacology. 35: 735-41. PMID 8887982 DOI: 10.1016/0028-3908(96)84645-4  0.43
1996 Gartside SE, McQuade R, Sharp T. Effects of repeated administration of 3,4-methylenedioxymethamphetamine on 5-hydroxytryptamine neuronal activity and release in the rat brain in vivo. The Journal of Pharmacology and Experimental Therapeutics. 279: 277-83. PMID 8859004 DOI: 10.1163/2211730X96X00153  0.529
1996 Hajós M, Gartside SE, Villa AE, Sharp T. Evidence for a repetitive (burst) firing pattern in a sub-population of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the rat. Neuroscience. 69: 189-97. PMID 8637617 DOI: 10.1016/0306-4522(95)00227-A  0.33
1995 Series HG, Masurier Ml, Gartside SE, Franklin M, Sharp T. Behavioural and neuroendocrine responses to D-fenfluramine in rats treated with neurotoxic amphetamines. Journal of Psychopharmacology. 9: 214-222. PMID 22297760 DOI: 10.1177/026988119500900303  0.42
1995 Smith S, Lindefors N, Hurd Y, Sharp T. Electroconvulsive shock increases dopamine D1 and D2 receptor mRNA in the nucleus accumbens of the rat. Psychopharmacology. 120: 333-40. PMID 8524981 DOI: 10.1007/Bf02311181  0.32
1995 Hajós M, Gartside SE, Sharp T. Inhibition of median and dorsal raphe neurones following administration of the selective serotonin reuptake inhibitor paroxetine. Naunyn-Schmiedeberg's Archives of Pharmacology. 351: 624-9. PMID 7675121 DOI: 10.1007/Bf00170162  0.466
1995 Burnet PW, Mead A, Eastwood SL, Lacey K, Harrison PJ, Sharp T. Repeated ECS differentially affects rat brain 5-HT1A and 5-HT2A receptor expression. Neuroreport. 6: 901-4. PMID 7612879 DOI: 10.1097/00001756-199504190-00019  0.488
1995 Gartside SE, Umbers V, Hajós M, Sharp T. Interaction between a selective 5-HT1A receptor antagonist and an SSRI in vivo: effects on 5-HT cell firing and extracellular 5-HT. British Journal of Pharmacology. 115: 1064-70. PMID 7582504 DOI: 10.1111/J.1476-5381.1995.Tb15919.X  0.515
1995 Hjorth S, Bengtsson HJ, Milano S, Lundberg JF, Sharp T. Studies on the role of 5-HT1A autoreceptors and alpha 1-adrenoceptors in the inhibition of 5-HT release--I. BMY7378 and prazosin. Neuropharmacology. 34: 615-20. PMID 7566497 DOI: 10.1016/0028-3908(95)00038-8  0.462
1995 Series HG, Cowen PJ, Sharp T. p-Chloroamphetamine (PCA), 3,4-methylenedioxy-methamphetamine (MDMA) and d-fenfluramine pretreatment attenuates d-fenfluramine-evoked release of 5-HT in vivo. Psychopharmacology. 116: 508-14. PMID 7535469 DOI: 10.1007/Bf02247485  0.416
1995 Gartside SE, Cowen PJ, Sharp T. Evidence that the large neutral amino acid L-valine decreases electrically-evoked release of 5-HT in rat hippocampus in vivo. Psychopharmacology. 109: 251-3. PMID 1365668 DOI: 10.1007/Bf02245511  0.461
1994 Done CJ, Sharp T. Biochemical evidence for the regulation of central noradrenergic activity by 5-HT1A and 5-HT2 receptors: microdialysis studies in the awake and anaesthetized rat. Neuropharmacology. 33: 411-21. PMID 7984279 DOI: 10.1016/0028-3908(94)90071-X  0.407
1993 Silverstone PH, Done C, Sharp T. In vivo monoamine release during naloxone-precipitated morphine withdrawal. Neuroreport. 4: 1043-5. PMID 8241461 DOI: 10.1097/00001756-199308000-00012  0.381
1993 Sharp T, McQuade R, Fozard JR, Hoyer D. The novel 5‐HT1A receptor antagonist, SDZ 216–525, decreases 5‐HT release in rat hippocampus in vivo British Journal of Pharmacology. 109: 699-702. PMID 8102935 DOI: 10.1111/J.1476-5381.1993.Tb13630.X  0.36
1993 Sharp T, McQuade R, Bramwell S, Hjorth S. Effect of acute and repeated administration of 5-HT1A receptor agonists on 5-HT release in rat brain in vivo. Naunyn-Schmiedeberg's Archives of Pharmacology. 348: 339-46. PMID 7904048 DOI: 10.1007/Bf00171331  0.462
1993 Gartside SE, Ellis PM, Sharp T, Cowen PJ. Selective 5-HT1A and 5-HT2 receptor-mediated adrenocorticotropin release in the rat: effect of repeated antidepressant treatments. European Journal of Pharmacology. 221: 27-33. PMID 1333974 DOI: 10.1016/0014-2999(92)90768-Y  0.479
1992 Sharp T, Bramwell SR, Grahame-Smith DG. Effect of acute administration of L-tryptophan on the release of 5-HT in rat hippocampus in relation to serotoninergic neuronal activity: an in vivo microdialysis study. Life Sciences. 50: 1215-23. PMID 1569829 DOI: 10.1016/0024-3205(92)90321-F  0.488
1992 Gartside SE, Cowen PJ, Sharp T. Effect of 5-hydroxy-L-tryptophan on the release of 5-HT in rat hypothalamus in vivo as measured by microdialysis. Neuropharmacology. 31: 9-14. PMID 1531865 DOI: 10.1016/0028-3908(92)90154-H  0.518
1992 Done CJ, Sharp T. Evidence that 5-HT2 receptor activation decreases noradrenaline release in rat hippocampus in vivo. British Journal of Pharmacology. 107: 240-5. PMID 1422575 DOI: 10.1111/j.1476-5381.1992.tb14493.x  0.401
1992 Grasby PM, Sharp T, Allen T, Grahame-Smith DG. The putative 5-HT1A antagonist BMY 7378 blocks 8-OH-DPAT-induced changes in local cerebral glucose utilization in the conscious rat. Neuropharmacology. 31: 547-51. PMID 1407394 DOI: 10.1016/0028-3908(92)90186-S  0.352
1992 Grasby PM, Sharp T, Allen T, Kelly PA, Grahame-Smith DG. Effects of the 5-HT1A partial agonists gepirone, ipsapirone and buspirone on local cerebral glucose utilization in the conscious rat. Psychopharmacology. 106: 97-101. PMID 1346724 DOI: 10.1007/Bf02253595  0.342
1991 Sharp T, Bramwell SR, Lambert P, Grahame-Smith DG. Effect of short- and long-term administration of lithium on the release of endogenous 5-HT in the hippocampus of the rat in vivo and in vitro. Neuropharmacology. 30: 977-84. PMID 1922695 DOI: 10.1016/0028-3908(91)90111-N  0.446
1991 Sharp T, Foster GA. Release of 5-hydroxytryptamine (5-HT) from medullary and mesencephalic raphé neurones after grafting to the rat hippocampus: Evidence for regulation by 5-HT1A autoreceptors Neuroscience Letters. 132: 179-182. PMID 1838408 DOI: 10.1016/0304-3940(91)90296-6  0.509
1991 Hjorth S, Sharp T. Effect of the 5-HT1A receptor agonist 8-OH-DPAT on the release of 5-HT in dorsal and median raphe-innervated rat brain regions as measured by in vivo microdialysis. Life Sciences. 48: 1779-86. PMID 1826937 DOI: 10.1016/0024-3205(91)90216-X  0.518
1991 Silverstone P, Done C, Sharp T. Naloxone-precipitated release of noradrenaline, but not serotonin or dopamine, is increased in brain during withdrawal in morphine dependent rats: an in vivo microdialysis study European Neuropsychopharmacology. 1: 414-415. DOI: 10.1016/0924-977X(91)90609-X  0.335
1990 Hjorth S, Sharp T. Mixed agonist/antagonist properties of NAN-190 at 5-HT1A receptors: behavioural and in vivo brain microdialysis studies. Life Sciences. 46: 955-63. PMID 2329921 DOI: 10.1016/0024-3205(90)90097-B  0.427
1990 Sharp T, Hjorth S. Application of brain microdialysis to study the pharmacology of the 5-HT1A autoreceptor. Journal of Neuroscience Methods. 34: 83-90. PMID 2259248 DOI: 10.1016/0165-0270(90)90045-H  0.522
1990 Backus LI, Sharp T, Grahame-Smith DG. Behavioural evidence for a functional interaction between central 5-HT2 and 5-HT1A receptors. British Journal of Pharmacology. 100: 793-9. PMID 2145051 DOI: 10.1111/J.1476-5381.1990.Tb14094.X  0.487
1990 Sharp T, Bramwell SR, Grahame-Smith DG. Release of endogenous 5-hydroxytryptamine in rat ventral hippocampus evoked by electrical stimulation of the dorsal raphe nucleus as detected by microdialysis: sensitivity to tetrodotoxin, calcium and calcium antagonists. Neuroscience. 39: 629-37. PMID 2097517 DOI: 10.1016/0306-4522(90)90247-2  0.324
1990 Sharp T, Backus LI, Hjorth S, Bramwell SR, Grahame-Smith DG. Further investigation of the in vivo pharmacological properties of the putative 5-HT1A antagonist, BMY 7378. European Journal of Pharmacology. 176: 331-40. PMID 1970304 DOI: 10.1016/0014-2999(90)90027-4  0.454
1990 Hjorth S, Sharp T, Liu Y. cis-(+)-8-OH-1-CH3-DPAT, (+)ALK-3, a novel stereoselective pharmacological probe for characterizing 5-HT release-controlling 5-HT1A autoreceptors. An in vivo brain microdialysis study. Naunyn-Schmiedeberg's Archives of Pharmacology. 341: 149-57. PMID 1692973 DOI: 10.1007/Bf00169724  0.498
1990 Sharp T, Bramwell S, Grahame-Smith DG. Effect of calcium channel antagonists on electrically-evoked release of 5-HT in rat hippocampus in vivo as studied by microdialysis European Journal of Pharmacology. 183: 1923. DOI: 10.1016/0014-2999(90)92268-N  0.414
1989 Sharp T, Bramwell SR, Hjorth S, Grahame-Smith DG. Pharmacological characterization of 8-OH-DPAT-induced inhibition of rat hippocampal 5-HT release in vivo as measured by microdialysis. British Journal of Pharmacology. 98: 989-97. PMID 2574066 DOI: 10.1111/J.1476-5381.1989.Tb14630.X  0.484
1989 Hjorth S, Sharp T, Hacksell U. Partial postsynaptic 5-HT1A agonist properties of the novel stereoselective 8-OH-DPAT analogue (+)cis-8-hydroxy-1-methyl-2-(di-n-propylamino)tetralin, (+)ALK-3. European Journal of Pharmacology. 170: 269-74. PMID 2533557 DOI: 10.1016/0014-2999(89)90549-9  0.433
1989 Sharp T, Bramwell SR, Clark D, Grahame-Smith DG. In vivo measurement of extracellular 5-hydroxytryptamine in hippocampus of the anaesthetized rat using microdialysis: changes in relation to 5-hydroxytryptaminergic neuronal activity. Journal of Neurochemistry. 53: 234-40. PMID 2470860 DOI: 10.1111/J.1471-4159.1989.Tb07319.X  0.514
1989 Sharp T, Bramwell SR, Grahame-Smith DG. 5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis. British Journal of Pharmacology. 96: 283-90. PMID 2466516 DOI: 10.1111/J.1476-5381.1989.Tb11815.X  0.501
1987 Sharp T, Zetterström T, Series HG, Carlsson A, Grahame-Smith DG, Ungerstedt U. HPLC-EC analysis of catechols and indoles in rat brain dialysates. Life Sciences. 41: 869-72. PMID 3613847 DOI: 10.1016/0024-3205(87)90183-4  0.338
1986 Sharp T, Zetterström T, Christmanson L, Ungerstedt U. p-Chloroamphetamine releases both serotonin and dopamine into rat brain dialysates in vivo. Neuroscience Letters. 72: 320-4. PMID 3822235 DOI: 10.1016/0304-3940(86)90534-3  0.368
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